393LN v 393P 344SQ v 393P Entrez fold fold probe set Gene Gene Symbol Gene cluster Gene Title p-value change p-value change

chemokine (C-C motif) ligand 21b /// chemokine (C-C motif) ligand 21a /// chemokine (C-C motif) ligand 21c 1419426_s_at 18829 /// Ccl21b /// Ccl2 1 - up 393 LN only (leucine) 0.0047 9.199837 0.45212 6.847887 nuclear factor of activated T-cells, cytoplasmic, calcineurin- 1447085_s_at 18018 Nfatc1 1 - up 393 LN only dependent 1 0.009048 12.065 0.13718 4.81 RIKEN cDNA 1453647_at 78668 9530059J11Rik1 - up 393 LN only 9530059J11 gene 0.002208 5.482897 0.27642 3.45171

transient receptor potential cation channel, subfamily 1457164_at 277328 Trpa1 1 - up 393 LN only A, member 1 0.000111 9.180344 0.01771 3.048114

regulating synaptic membrane 1422809_at 116838 Rims2 1 - up 393 LN only exocytosis 2 0.001891 8.560424 0.13159 2.980501

glial cell line derived neurotrophic factor family receptor alpha 1433716_x_at 14586 Gfra2 1 - up 393 LN only 2 0.006868 30.88736 0.01066 2.811211 1446936_at ------1 - up 393 LN only --- 0.007695 6.373955 0.11733 2.480287 zinc finger protein 1438742_at 320683 Zfp629 1 - up 393 LN only 629 0.002644 5.231855 0.38124 2.377016

phospholipase A2, 1426019_at 18786 Plaa 1 - up 393 LN only activating protein 0.008657 6.2364 0.12336 2.262117 1445314_at 14009 Etv1 1 - up 393 LN only ets variant gene 1 0.007224 3.643646 0.36434 2.01989

ciliary rootlet coiled- 1427338_at 230872 Crocc 1 - up 393 LN only coil, rootletin 0.002482 7.783242 0.49977 1.794171

expressed sequence 1436585_at 99463 BB182297 1 - up 393 LN only BB182297 0.001123 2.999853 0.0773 1.753034 RIKEN cDNA 1423853_at 76161 6330527O06R 1 - up 393 LN only 6330527O06 gene 0.005902 4.013889 0.6354 1.744792

zinc finger and BTB domain containing 10 /// similar to zinc finger and BTB domain containing 1436067_at 229055 // Zbtb10 /// LOC 1 - up 393 LN only 10 2.21E-05 2.610234 0.10709 1.688034

zinc finger, DHHC 1455368_at 69035 Zdhhc3 1 - up 393 LN only domain containing 3 8.69E-05 2.506496 0.06777 1.639498 1452857_at ------1 - up 393 LN only --- 0.00062 2.921152 0.00275 1.591588 RIKEN cDNA 1453375_at 76871 4930422N03Ri1 - up 393 LN only 4930422N03 gene 8.25E-05 2.422089 0.03009 1.564106 RWD domain 1430167_a_at 73170 Rwdd3 1 - up 393 LN only containing 3 0.000497 2.158135 0.19453 1.522726 zinc finger, X-linked, duplicated A /// similar to Zinc finger X-linked protein 1444595_at 668171 // Zxda /// LOC661 - up 393 LN only ZXDA 0.005966 2.409508 0.09151 1.511482 1457577_at ------1 - up 393 LN only --- 0.008635 3.270127 0.9824 1.503474 ELOVL family member 7, elongation of long chain fatty acids 1440312_at 74559 Elovl7 1 - up 393 LN only (yeast) 0.000744 2.137495 0.03381 1.47027 RIKEN cDNA 1460107_at 330577 1700129I04Rik1 - up 393 LN only 1700129I04 gene 0.009676 2.112971 0.2904 1.462082 RIKEN cDNA 1460178_at 66887 1300002A08Ri 1 - up 393 LN only 1300002A08 gene 0.000398 2.367794 0.07672 1.459048 RIKEN cDNA 1434232_a_at 67048 2610030H06Ri1 - up 393 LN only 2610030H06 gene 0.000117 2.367624 0.00136 1.446903 RAN binding protein 1445883_at 19386 Ranbp2 1 - up 393 LN only 2 0.005392 3.849845 0.63772 1.428019 nuclear transport 1449017_at 68051 Nutf2 1 - up 393 LN only factor 2 0.000155 2.046963 0.00739 1.418209 RIKEN cDNA 1434870_at 66523 2810004N23Ri1 - up 393 LN only 2810004N23 gene 0.001229 2.138042 0.07972 1.410107

1454625_at 70998 Phf6 1 - up 393 LN only PHD finger protein 6 0.000167 2.006085 0.00578 1.409993

heparan sulfate (glucosamine) 3-O- 1435622_at 15478 Hs3st3a1 1 - up 393 LN only sulfotransferase 3A1 0.003189 2.004507 0.09586 1.408886 1425172_at 212541 Rho 1 - up 393 LN only rhodopsin 0.004979 3.513026 0.98944 1.405812 tRNA methyltranferase 12 homolog (S. 1430537_at 68260 Trmt12 1 - up 393 LN only cerevisiae) 0.009989 6.230278 1 1.401023

non-catalytic region of tyrosine kinase 1447271_at 17973 Nck1 1 - up 393 LN only adaptor protein 1 0.002496 1.933052 0.96191 1.397223 RIKEN cDNA 1418384_at 68117 9430083G14R 1 - up 393 LN only 9430083G14 gene 0.001978 2.097288 0.05514 1.396671 cleavage and polyadenylation 1420936_s_at 51786 Cpsf2 1 - up 393 LN only specific factor 2 0.002928 2.176774 0.07287 1.392015 nucleosome binding 1418152_at 50887 Nsbp1 1 - up 393 LN only protein 1 0.005352 2.607296 0.04863 1.383277 TBC1 domain family, 1435292_at 210789 Tbc1d4 1 - up 393 LN only member 4 0.001834 1.942539 0.33479 1.373709 TNFRSF1A- associated via death 1429117_at 71609 Tradd 1 - up 393 LN only domain 0.002897 2.119899 0.11415 1.373465 RWD domain 1451809_s_at 73170 Rwdd3 1 - up 393 LN only containing 3 0.000983 1.843427 0.1859 1.371235 RIKEN cDNA 1418732_s_at 67836 1500041N16Ri1 - up 393 LN only 1500041N16 gene 0.003433 1.974302 0.09934 1.370555 programmed cell 1418127_a_at 26926 Pdcd8 1 - up 393 LN only death 8 0.000158 1.892441 0.03143 1.362078

growth factor receptor bound protein 2-associated 1426589_at 210710 Gab3 1 - up 393 LN only protein 3 0.009151 1.869349 0.18953 1.360899 1434952_at 18117 Cox4nb 1 - up 393 LN only COX4 neighbor 0.006898 1.768981 0.19208 1.355266 proliferation- 1420142_s_at 18813 Pa2g4 1 - up 393 LN only associated 2G4 0.00115 1.944031 0.02386 1.354887

TATA box binding protein (Tbp)- associated factor, 1423483_s_at 21341 Taf1c 1 - up 393 LN only RNA polymerase I, C 0.000817 2.130636 0.0457 1.35166 G1 to S phase 1455173_at 14852 Gspt1 1 - up 393 LN only transition 1 0.004005 1.83883 0.06863 1.351626 programmed cell death 6 interacting 1415937_s_at 18571 Pdcd6ip 1 - up 393 LN only protein 0.001589 1.845318 0.08878 1.346551

DnaJ (Hsp40) homolog, subfamily 1417182_at 56445 Dnaja2 1 - up 393 LN only A, member 2 0.000151 2.281091 0.1553 1.346201 mitogen-activated protein kinase kinase kinase kinase 1427084_a_at 399510 Map4k5 1 - up 393 LN only 5 0.00096 2.147488 0.04999 1.341439

membrane-bound transcription factor 1436883_at 270669 Mbtps2 1 - up 393 LN only peptidase, site 2 0.001076 1.80863 0.06545 1.338257 RIKEN cDNA 1434233_at 67048 2610030H06Ri1 - up 393 LN only 2610030H06 gene 0.000319 1.950389 0.00592 1.337195 1426463_at 268566 Gphn 1 - up 393 LN only gephyrin 0.009157 2.091449 0.23189 1.335958 RIKEN cDNA 1434699_at 217558 6030408C04Ri1 - up 393 LN only 6030408C04 gene 0.00187 1.921027 0.04138 1.333538

suppressor of hairy wing homolog 3 1427983_at 208968 Suhw3 1 - up 393 LN only (Drosophila) 0.000574 2.133975 0.02062 1.3317 RIKEN cDNA 1419687_at 107227 D930010J01Ri 1 - up 393 LN only D930010J01 gene 0.001651 2.038994 0.02113 1.331222 RIKEN cDNA 1439131_at 353170 4932441K18Ri 1 - up 393 LN only 4932441K18 gene 0.000432 2.497289 0.04961 1.322917 Casitas B-lineage 1437203_at 104836 Cbll1 1 - up 393 LN only lymphoma-like 1 0.002398 1.995673 0.13787 1.321443

glutaryl-Coenzyme A 1448717_at 270076 Gcdh 1 - up 393 LN only dehydrogenase 0.001656 1.812838 0.04061 1.320628 methyl CpG binding 1449266_at 17257 Mecp2 1 - up 393 LN only protein 2 0.003264 1.731564 0.20782 1.315433 TSR2, 20S rRNA accumulation, homolog (S. 1426939_at 69499 Tsr2 1 - up 393 LN only cerevisiae) 0.002791 1.912267 0.15258 1.309596 YLP motif containing 1443773_at 56531 Ylpm1 1 - up 393 LN only 1 0.0034 1.932832 0.27178 1.304508 ring finger protein 1428415_at 66381 Rnf113a2 1 - up 393 LN only 113A2 0.002152 2.146608 0.03041 1.302093

protein arginine N- 1451248_at 214572 Prmt7 1 - up 393 LN only methyltransferase 7 0.00066 2.151487 0.12218 1.301213 cDNA sequence 1451400_at 237221 BC023488 1 - up 393 LN only BC023488 0.007667 1.964082 0.07994 1.297829

splicing factor, 1416721_s_at 67996 Sfrs6 1 - up 393 LN only arginine/serine-rich 6 0.00016 1.757945 0.09721 1.296628 HCF-binding transcription factor 1452856_at 233490 Zf 1 - up 393 LN only Zhangfei 0.001244 2.003237 0.01742 1.293312

NIN1/RPN12 binding protein 1 homolog 1454957_at 67619 Nob1 1 - up 393 LN only (S. cerevisiae) 0.000643 1.981012 0.1341 1.290964 1430979_a_at 21672 Prdx2 1 - up 393 LN only peroxiredoxin 2 3.77E-05 1.861295 0.16116 1.288833 deoxyhypusine 1434003_a_at 330817 Dhps 1 - up 393 LN only synthase 0.000571 1.996662 0.21378 1.28727 B-cell receptor- associated protein 1417077_at 12033 Bcap29 1 - up 393 LN only 29 0.003306 2.141084 0.06873 1.281952 isocitrate dehydrogenase 3 1416789_at 15929 Idh3g 1 - up 393 LN only (NAD+), gamma 0.008423 1.676854 0.04985 1.281719

autophagy-related 4A (yeast) /// similar to Cysteine protease ATG4A (Autophagy- related protein 4 homolog A) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (AUT-like 2 cysteine endopeptidase) /// similar to Cysteine protease ATG4A (Autophagy-related protein 4 homolog A) (Autophagin-2) (Autophagy-related cysteine endopeptidase 2) (AUT-like 2 cysteine 1434662_at 103003 // Atg4a /// LOC6 1 - up 393 LN only endopeptidase) 0.001833 1.661673 0.01474 1.27908 lysyl-tRNA synthetase /// similar to lysyl-tRNA 1416068_at 631033 // Kars /// LOC63 1 - up 393 LN only synthetase 0.004005 1.727773 0.05616 1.279074 ATP-binding cassette, sub-family 1419572_a_at 19300 Abcd4 1 - up 393 LN only D (ALD), member 4 0.006188 1.881255 0.05932 1.278023 RIKEN cDNA 1429984_at 70567 5730455O13R 1 - up 393 LN only 5730455O13 gene 0.008739 2.044919 0.18566 1.275353

1437743_at 11569 Aebp2 1 - up 393 LN only AE binding protein 2 0.005685 1.843111 0.14235 1.269637 zinc finger and BTB domain containing 1434022_at 56805 Zbtb33 1 - up 393 LN only 33 0.001137 1.642324 0.02204 1.26761 zinc finger protein 1418397_at 27081 Zfp275 1 - up 393 LN only 275 2.03E-05 1.859679 0.02755 1.265593 RIKEN cDNA 1423358_at 66275 1810009K13Ri 1 - up 393 LN only 1810009K13 gene 0.00226 1.987081 0.02411 1.263178 preimplantation 1423168_at 19070 Prei3 1 - up 393 LN only protein 3 0.000841 1.70667 0.0266 1.261795

BRCA1/BRCA2- containing complex, 1456141_x_at 210766 Brcc3 1 - up 393 LN only subunit 3 0.005435 3.330441 0.20854 1.259452 cullin associated and neddylation 1455751_at 71902 Cand1 1 - up 393 LN only disassociated 1 0.007591 2.649497 0.33527 1.259213

N-acetyltransferase 1428410_at 72117 Nat13 1 - up 393 LN only 13 0.007396 1.685089 0.02767 1.25753 RAB6B, member RAS oncogene 1434914_at 270192 Rab6b 1 - up 393 LN only family 0.006065 3.355629 0.56484 1.256319 Serpine1 mRNA 1418565_at 66870 Serbp1 1 - up 393 LN only binding protein 1 0.000914 1.921633 0.01969 1.255466 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated 1440187_at 209361 Taf3 1 - up 393 LN only factor 0.001583 1.760387 0.134 1.2553

1435070_at 11569 Aebp2 1 - up 393 LN only AE binding protein 2 0.000158 1.714892 0.02927 1.254636 RIKEN cDNA 1429061_at 67892 1810063B05Ri 1 - up 393 LN only 1810063B05 gene 0.006297 1.715633 0.05741 1.254054 nucleolar and coiled- body phosphoprotein 1428870_at 70769 Nolc1 1 - up 393 LN only 1 0.001269 3.323831 0.23528 1.253402 TNFRSF1A- associated via death 1452622_a_at 71609 Tradd 1 - up 393 LN only domain 0.000154 1.968661 0.07793 1.253133 Prostaglandin I2 (prostacyclin) 1445044_at 19223 Ptgis 1 - up 393 LN only synthase 0.00061 1.553035 0.24688 1.25192 phosphoribosyl pyrophosphate 1416052_at 19139 Prps1 1 - up 393 LN only synthetase 1 0.004799 2.085695 0.04869 1.248936 polyglutamine 1417731_at 54633 Pqbp1 1 - up 393 LN only binding protein 1 0.00344 1.623939 0.0651 1.248335 guanine nucleotide binding protein-like 3 1439009_at 237107 Gnl3l 1 - up 393 LN only (nucleolar)-like 0.000812 1.707166 0.05885 1.244308 1418357_at 15228 Foxg1 1 - up 393 LN only forkhead box G1 5.32E-05 8.832828 0.25222 1.244051

THAP domain containing, apoptosis associated 1421177_at 66816 Thap2 1 - up 393 LN only protein 2 0.007783 1.605873 0.26962 1.244047

ubiquitin-conjugating 1417984_at 70620 Ube2v2 1 - up 393 LN only enzyme E2 variant 2 5.62E-05 2.060968 0.0474 1.243893 RIKEN cDNA 1428519_at 66497 2610528E23Ri 1 - up 393 LN only 2610528E23 gene 0.001367 2.01918 0.09347 1.237214 hairy and enhancer of split 6 1436050_x_at 55927 Hes6 1 - up 393 LN only (Drosophila) 0.00134 1.567468 0.04598 1.23703 ubiquitin specific 1444437_at 17847 Usp34 1 - up 393 LN only peptidase 34 0.002348 1.519375 0.14029 1.235918 phosphodiesterase 1419389_at 23984 Pde10a 1 - up 393 LN only 10A 0.00157 10.59487 0.60425 1.233259 tetratricopeptide 1438631_x_at 234875 Ttc13 1 - up 393 LN only repeat domain 13 0.005941 1.687838 0.01549 1.232704 zinc finger protein 1433953_at 246196 Zfp277 1 - up 393 LN only 277 0.00241 1.691253 0.08876 1.232506 similar to bromodomain 1436469_at 634327 LOC634327 1 - up 393 LN only containing 7 0.009578 1.662732 0.15365 1.227839 integrin alpha FG- GAP repeat 1419041_at 71927 Itfg1 1 - up 393 LN only containing 1 0.004336 1.583879 0.07611 1.226977 RIKEN cDNA 1428652_at 71675 0610010F05Ri 1 - up 393 LN only 0610010F05 gene 0.006534 1.574069 0.08365 1.226831 RIKEN cDNA 3100002L24 gene /// RIKEN cDNA 9230108I15 gene /// similar to gonadotropin inducible ovarian transcription factor 1 /// similar to zinc finger protein 709 /// similar to zinc finger protein 709 /// similar to zinc finger protein 709 /// similar to zinc finger protein 709 /// similar to gonadotropin inducible ovarian transcription factor 1 /// similar to zinc finger protein 97 /// similar to gonadotropin inducible ovarian 1447977_x_at 626832 // 3100002L24Ri 1 - up 393 LN only transcription factor 1 0.001063 1.75807 0.07116 1.225565 cleavage and polyadenylation 1431089_at 51786 Cpsf2 1 - up 393 LN only specific factor 2 4.38E-05 1.977768 0.08317 1.224928 1418285_at 13641 Efnb1 1 - up 393 LN only ephrin B1 0.002901 1.719549 0.30463 1.22394 TWIST neighbor /// similar to TWIST neighbor /// similar to 1428633_at 28071 /// Twistnb /// LOC1 - up 393 LN only TWIST neighbor 0.003113 2.202676 0.28388 1.221766

abhydrolase domain 1417566_at 67469 Abhd5 1 - up 393 LN only containing 5 0.006692 1.542068 0.24167 1.221508 1450938_at ------1 - up 393 LN only --- 0.00251 1.943363 0.21148 1.22136

influenza virus NS1A 1420961_a_at 117198 Ivns1abp 1 - up 393 LN only binding protein 0.006429 2.082511 0.48775 1.22031 RAB interacting 1419927_s_at 98710 Rabif 1 - up 393 LN only factor 0.006103 1.502535 0.09946 1.218885

UTP6, small subunit (SSU) processome component, homolog 1424501_at 216987 Utp6 1 - up 393 LN only (yeast) 0.005318 1.573067 0.12226 1.21617 FUN14 domain 1424215_at 72018 Fundc1 1 - up 393 LN only containing 1 0.00142 1.705533 0.0647 1.215179 hydroxyacyl- Coenzyme A dehydrogenase type 1438391_x_at 15108 Hadh2 1 - up 393 LN only II 0.003738 1.699219 0.09908 1.213872 RIKEN cDNA 1434671_at 98262 B230337E12R 1 - up 393 LN only B230337E12 gene 0.008119 1.565111 0.08282 1.213401

solute carrier family 16 (monocarboxylic acid transporters), 1436368_at 72472 Slc16a10 1 - up 393 LN only member 10 0.003371 1.751608 0.14668 1.211387

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1423711_at 69702 Ndufaf1 1 - up 393 LN only assembly factor 1 0.003565 1.688649 0.18958 1.209088

cofactor required for Sp1 transcriptional 1443597_at 26896 Crsp2 1 - up 393 LN only activation, subunit 2 0.004799 1.575319 0.16645 1.207797 1443607_at ------1 - up 393 LN only --- 0.009417 1.863415 0.50425 1.204351 tetratricopeptide 1437709_x_at 234875 Ttc13 1 - up 393 LN only repeat domain 13 0.000345 1.546043 0.02966 1.204194 dipeptidylpeptidase 1436479_a_at 83768 Dpp7 1 - up 393 LN only 7 0.000221 2.102077 0.6357 1.204112

RIKEN cDNA 2610528E23 gene /// FGF receptor 1430423_s_at 233575 // 2610528E23Ri 1 - up 393 LN only activating protein 1 0.002599 1.735209 0.25755 1.20237 Atpase, class VI, 1452496_at 320940 Atp11c 1 - up 393 LN only type 11C 0.003568 1.527953 0.23471 1.200351 RIKEN cDNA 1452607_at 67048 2610030H06Ri1 - up 393 LN only 2610030H06 gene 0.005102 1.536408 0.07873 1.199351 serine/threonine 1426160_a_at 20872 Stk16 1 - up 393 LN only kinase 16 0.002903 1.590577 0.13077 1.199266 1456625_at ------1 - up 393 LN only --- 0.008907 1.771458 0.01397 1.198978

anaphase promoting 1429376_s_at 68999 Anapc10 1 - up 393 LN only complex subunit 10 0.001733 1.705705 0.14566 1.19881 golgi apparatus 1460554_s_at 20340 Glg1 1 - up 393 LN only protein 1 0.006077 1.68076 0.18892 1.197611 solute carrier family 14 (urea transporter), member 1448640_at 108052 Slc14a1 1 - up 393 LN only 1 0.000835 11.2016 0.39538 1.197596

protein phosphatase 2, regulatory subunit B (B56), epsilon 1428462_at 26932 Ppp2r5e 1 - up 393 LN only isoform 0.003753 1.585906 0.11045 1.195655 T-cell lymphoma invasion and 1418057_at 21844 Tiam1 1 - up 393 LN only metastasis 1 0.000734 2.268376 0.37542 1.193996 nucleotide binding 1429278_at 76826 Nubpl 1 - up 393 LN only protein-like 0.003346 2.314197 0.11916 1.191134 UPF3 regulator of nonsense transcripts 1434842_s_at 68134 Upf3b 1 - up 393 LN only homolog B (yeast) 0.004564 1.695367 0.1101 1.190713 RIKEN cDNA 1458400_at 319927 9630050P21Ri 1 - up 393 LN only 9630050P21 gene 0.00998 2.072461 0.45396 1.189965 1457089_at ------1 - up 393 LN only --- 0.001298 1.597692 0.20204 1.188656

ribosomal protein L37a /// similar to 60S ribosomal protein L37a /// similar to 60S ribosomal protein L37a /// similar to 60S ribosomal protein L37a /// similar to 60S ribosomal protein 1416218_x_at 19981 /// Rpl37a /// LOC 1 - up 393 LN only L37a 0.002857 1.504902 0.22751 1.188483 kelch-like 15 1438247_at 236904 Klhl15 1 - up 393 LN only (Drosophila) 0.004877 1.610839 0.39319 1.18829 RIKEN cDNA 1438553_x_at 67609 4930453N24Ri1 - up 393 LN only 4930453N24 gene 0.001134 1.630927 0.08547 1.187439

translin-associated 1423395_at 53424 Tsnax 1 - up 393 LN only factor X 0.003917 1.643959 0.12415 1.186323 tetratricopeptide 1451351_at 234875 Ttc13 1 - up 393 LN only repeat domain 13 0.000571 1.639583 0.05892 1.185255 leucine-zipper-like transcriptional 1450927_at 66863 Lztr1 1 - up 393 LN only regulator, 1 0.005854 1.851386 0.18985 1.183797

Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1447068_at 18710 Pik3r3 1 - up 393 LN only 3 (p55) 0.002921 2.874305 0.65743 1.181841 cytochrome P450, family 4, subfamily f, 1418767_at 170716 Cyp4f13 1 - up 393 LN only polypeptide 13 0.006718 1.567971 0.09919 1.181107

ADP-ribosylarginine 1448333_at 11544 Adprh 1 - up 393 LN only hydrolase 0.003748 1.631695 0.12764 1.178658

neuron derived 1417879_at 66208 Nenf 1 - up 393 LN only neurotrophic factor 0.001942 1.531157 0.27524 1.174919 adaptor-related protein complex AP- 1451665_a_at 11782 Ap4s1 1 - up 393 LN only 4, sigma 1 0.001269 1.63713 0.02055 1.172988 TRM1 tRNA methyltransferase 1 homolog (S. 1451249_at 212528 Trmt1 1 - up 393 LN only cerevisiae) 0.000798 2.100871 0.07064 1.172154 zinc finger protein 1452611_at 78913 Zfp294 1 - up 393 LN only 294 0.000689 1.717054 0.07416 1.171873 Hus1 homolog (S. 1418308_at 15574 Hus1 1 - up 393 LN only pombe) 0.001286 1.569712 0.11142 1.17178 amyloid beta precursor protein 1423781_at 234664 Appbp1 1 - up 393 LN only binding protein 1 0.003856 1.532585 0.13672 1.170554 protein disulfide isomerase 1424650_at 72599 Pdia5 1 - up 393 LN only associated 5 0.004514 2.971316 0.35566 1.169898 RIKEN cDNA 1428201_at 68544 2310036O22R 1 - up 393 LN only 2310036O22 gene 0.000356 1.505411 0.04419 1.168918

protein phosphatase 1, regulatory 1456830_at 66849 Ppp1r2 1 - up 393 LN only (inhibitor) subunit 2 0.001591 1.640592 0.11709 1.166436 DNA segment, Chr 8, ERATO Doi 457, 1436020_at 101994 D8Ertd457e 1 - up 393 LN only expressed 0.003884 1.695569 0.4226 1.164742

anaphase promoting 1429375_at 68999 Anapc10 1 - up 393 LN only complex subunit 10 0.005616 1.732381 0.35151 1.164584 dipeptidylpeptidase 1435680_a_at 83768 Dpp7 1 - up 393 LN only 7 0.006956 2.506438 0.68464 1.161674 immunoglobulin (CD79A) binding 1420000_s_at 18518 Igbp1 1 - up 393 LN only protein 1 0.001503 1.645122 0.0267 1.161327 proteasome (prosome, macropain) 26S subunit, non- 1432820_at 17463 Psmd7 1 - up 393 LN only ATPase, 7 0.000867 1.71621 0.0797 1.159682 CREBBP/EP300 1448405_a_at 58521 Cri1 1 - up 393 LN only inhibitory protein 1 0.001715 1.595743 0.34269 1.158412 vaccinia related 1453343_s_at 69922 Vrk2 1 - up 393 LN only kinase 2 0.000228 1.726154 0.29026 1.157984 deoxyuridine 1419269_at 110074 Dut 1 - up 393 LN only triphosphatase 0.001074 2.222469 0.35178 1.154119

abhydrolase domain 1434526_at 384214 Abhd7 1 - up 393 LN only containing 7 0.002901 2.629567 0.712 1.153803 1434919_at ------1 - up 393 LN only Transcribed locus 4.4E-05 1.500143 0.05357 1.153176 ATP-binding cassette, sub-family E (OABP), member 1416015_s_at 24015 Abce1 1 - up 393 LN only 1 0.00167 1.565493 0.03774 1.152689

carbonic anhydrase 1447928_at 56078 Car5b 1 - up 393 LN only 5b, mitochondrial 0.000226 2.649508 0.20594 1.151428 splicing factor, arginine/serine-rich 3 1416151_at 20383 Sfrs3 1 - up 393 LN only (SRp20) 0.006304 1.565488 0.23799 1.151206 RIKEN cDNA 1439387_x_at 66965 2310061F22Ri 1 - up 393 LN only 2310061F22 gene 0.008002 1.68407 0.42285 1.148471

RIKEN cDNA 1455428_at 77938 A930008G19R 1 - up 393 LN only A930008G19 gene 0.005949 1.554331 0.86764 1.14761 zinc finger CCCH 1426999_at 75553 Zc3h14 1 - up 393 LN only type containing 14 0.004541 1.6786 0.13899 1.145861 dihydroorotate 1417582_s_at 56749 Dhodh 1 - up 393 LN only dehydrogenase 0.00245 1.831169 0.2925 1.145553 1418781_at 66176 Nat9 1 - up 393 LN only NAT9 0.002677 1.53015 0.17651 1.142717

par-3 (partitioning defective 3) homolog 1436764_at 93742 Pard3 1 - up 393 LN only (C. elegans) 0.000188 1.735348 0.57468 1.140186 RIKEN cDNA 1433738_at 214627 5730445M16R 1 - up 393 LN only 5730445M16 gene 0.0006 1.772431 0.12595 1.139009 dihydroorotate 1417581_at 56749 Dhodh 1 - up 393 LN only dehydrogenase 0.002928 1.675029 0.17181 1.137912

mediator of RNA polymerase II transcription, subunit 1425585_at 59024 Med12 1 - up 393 LN only 12 homolog (yeast) 0.000147 1.585687 0.15424 1.132437 Vac14 homolog (S. 1416231_at 234729 Vac14 1 - up 393 LN only cerevisiae) 0.005696 1.667915 0.2121 1.131718

similar to Nucleolar phosphoprotein p130 (Nucleolar 130 kDa protein) (140 kDa nucleolar phosphoprotein) (Nopp140) (Nucleolar and coiled-body 1445504_at 331392 LOC331392 1 - up 393 LN only phosphoprotein 1) 0.009098 1.550894 0.27507 1.130257 RIKEN cDNA 1453045_at 77048 4921537D05Ri1 - up 393 LN only 4921537D05 gene 0.008939 1.566268 0.05268 1.126446 RIKEN cDNA 1452682_at 78755 4632404H22Ri1 - up 393 LN only 4632404H22 gene 0.000757 1.727479 0.27467 1.125655 thymidine kinase 2, 1426100_a_at 57813 Tk2 1 - up 393 LN only mitochondrial 0.006482 1.523011 0.23931 1.122753 RAD51-like 3 (S. 1425944_a_at 19364 Rad51l3 1 - up 393 LN only cerevisiae) 0.003351 1.685264 0.45001 1.121464

apoptosis, caspase 1452996_a_at 74268 Aven 1 - up 393 LN only activation inhibitor 0.005424 1.548238 0.544 1.120344

glycine cleavage system protein H (aminomethyl carrier) /// similar to Glycine cleavage system H protein, mitochondrial 1432164_a_at 674321 // Gcsh /// LOC671 - up 393 LN only precursor 0.001047 1.543818 0.30643 1.120236 immunoglobulin (CD79A) binding 1460737_at 18518 Igbp1 1 - up 393 LN only protein 1 0.000712 2.096349 0.40142 1.117831

LanC (bacterial lantibiotic synthetase 1427011_a_at 14768 Lancl1 1 - up 393 LN only component C)-like 1 0.003034 1.529231 0.10954 1.116563 casein kinase 2, alpha prime 1429302_at 13000 Csnk2a2 1 - up 393 LN only polypeptide 0.007428 1.801718 0.39493 1.115843 1-acylglycerol-3- phosphate O- 1433817_at 28169 Agpat3 1 - up 393 LN only acyltransferase 3 0.003943 1.59844 0.29639 1.114463 breast cancer metastasis- 1452850_s_at 52592 Brms1l 1 - up 393 LN only suppressor 1-like 0.000246 1.605638 0.20708 1.110984 component of oligomeric golgi 1426821_at 97484 Cog8 1 - up 393 LN only complex 8 0.006842 1.710475 0.35669 1.107994 ATP-binding cassette, sub-family E (OABP), member 1416014_at 24015 Abce1 1 - up 393 LN only 1 0.002009 1.848707 0.52765 1.105762 NF-kappaB 1434398_at 77286 Nkrf 1 - up 393 LN only repressing factor 0.001989 1.700187 0.43618 1.105471 Ras-GTPase- activating protein SH3-domain binding 1455060_at 27041 RP23-336J1.4 1 - up 393 LN only protein 0.003606 1.598538 0.49576 1.100591

DnaJ (Hsp40) homolog, subfamily 1417183_at 56445 Dnaja2 1 - up 393 LN only A, member 2 0.006099 1.764523 0.65007 1.099495 WW domain containing E3 ubiquitin protein 1448145_at 66894 Wwp2 1 - up 393 LN only ligase 2 0.000301 2.003174 0.60694 1.09866 1443822_s_at ------1 - up 393 LN only --- 0.006394 1.538138 0.52148 1.098545

ubiquitin carboxyl- 1419453_at 56207 Uchl5 1 - up 393 LN only terminal esterase L5 0.001422 1.710344 0.59947 1.097649

peroxisomal trans-2- 1448910_at 111175 Pecr 1 - up 393 LN only enoyl-CoA reductase 0.004487 1.729373 0.45496 1.096427 SCY1-like 2 (S. 1436313_at 213326 Scyl2 1 - up 393 LN only cerevisiae) 0.005585 1.780408 0.36099 1.096242 cDNA sequence 1435379_at 382038 AK122209 1 - up 393 LN only AK122209 0.002401 1.690799 0.26602 1.095678

abhydrolase domain 1428276_at 68904 Abhd13 1 - up 393 LN only containing 13 0.004957 1.660223 0.66118 1.0942

DiGeorge syndrome 1452434_s_at 13353 Dgcr6 1 - up 393 LN only critical region gene 6 0.001592 1.644663 0.51732 1.0941 angel homolog 1 1424844_at 68737 Angel1 1 - up 393 LN only (Drosophila) 0.000627 1.793642 0.63146 1.093173

ASF1 anti-silencing function 1 homolog 1423714_at 66929 Asf1b 1 - up 393 LN only B (S. cerevisiae) 0.002327 1.693334 0.49241 1.092851 interleukin-1 receptor-associated kinase 1 binding 1431771_a_at 65099 Irak1bp1 1 - up 393 LN only protein 1 0.000498 1.613404 0.59799 1.092514 WD repeat domain 1434552_at 70465 Wdr77 1 - up 393 LN only 77 0.002186 1.57661 0.16823 1.087635 1453833_a_at 19819 Rnaseh1 1 - up 393 LN only ribonuclease H1 0.003043 1.792518 0.17282 1.085606 craniofacial development protein 1416742_at 23837 Cfdp1 1 - up 393 LN only 1 6.83E-07 1.595332 0.51814 1.08496

1426472_at 22710 Zfp52 1 - up 393 LN only zinc finger protein 52 0.009545 1.526785 0.49883 1.084055 protein tyrosine phosphatase-like (proline instead of catalytic arginine), 1437329_at 70757 Ptplb 1 - up 393 LN only member b 0.004968 1.514886 0.42361 1.083801 component of oligomeric golgi 1419809_s_at 102339 Cog4 1 - up 393 LN only complex 4 0.000348 1.520374 0.3035 1.081401

DiGeorge syndrome 1428753_a_at 13353 Dgcr6 1 - up 393 LN only critical region gene 6 0.002826 1.91041 0.70295 1.081056 RIKEN cDNA 1417478_a_at 59032 4930511A21Ri 1 - up 393 LN only 4930511A21 gene 0.005022 1.613338 0.21916 1.080093 prostaglandin E 1417591_at 96979 Ptges2 1 - up 393 LN only synthase 2 0.006733 1.562195 0.66455 1.074 1434243_s_at ------1 - up 393 LN only --- 0.00244 2.011697 0.7873 1.073429 phenylalanine-tRNA synthetase-like, 1424907_a_at 66590 Farsla 1 - up 393 LN only alpha subunit 0.005696 1.537343 0.53308 1.072618 RIKEN cDNA 1428122_s_at 72543 2610528K11Ri 1 - up 393 LN only 2610528K11 gene 0.007477 1.598223 0.56488 1.067982 1457259_at ------1 - up 393 LN only --- 0.006086 1.506469 0.41838 1.067276 1453117_at 20931 Surf2 1 - up 393 LN only surfeit gene 2 0.00055 10.75806 0.79759 1.064516 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to solute carrier family 25, member 1438922_x_at 11740 /// Slc25a5 /// LOC1 - up 393 LN only A6 0.003951 1.726697 0.64628 1.064494 breast cancer metastasis- 1460443_at 52592 Brms1l 1 - up 393 LN only suppressor 1-like 0.003588 1.636102 0.54862 1.060513 polymerase (DNA directed), delta 2, 1448277_at 18972 Pold2 1 - up 393 LN only regulatory subunit 0.007306 1.81227 0.59447 1.060452 transcription factor 1418167_at 83383 Tcfap4 1 - up 393 LN only AP4 0.005147 1.604373 0.52212 1.059521 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to solute carrier family 25, member 1438360_x_at 11740 /// Slc25a5 /// LOC1 - up 393 LN only A6 0.004137 1.713378 0.60532 1.05692

ubiquitin-conjugating enzyme E2A, RAD6 homolog (S. 1417609_at 22209 Ube2a 1 - up 393 LN only cerevisiae) 0.004745 1.82443 0.50136 1.05429

expressed sequence 1458355_x_at 103784 AI553587 1 - up 393 LN only AI553587 0.00733 1.697494 0.70805 1.050062 SUB1 homolog (S. 1422692_at 20024 Sub1 1 - up 393 LN only cerevisia 0.008829 1.841738 0.64912 1.048455 TRM1 tRNA methyltransferase 1 homolog (S. 1436494_x_at 212528 Trmt1 1 - up 393 LN only cerevisiae) 0.004768 1.721766 0.45781 1.048174 exosome component 1435544_at 72544 Exosc6 1 - up 393 LN only 6 0.001701 1.565959 0.61962 1.047304 excision repair cross- complementing rodent repair deficiency, complementation 1448984_at 50505 Ercc4 1 - up 393 LN only group 4 0.005022 1.623418 0.66465 1.046612 1422554_at 66647 Ndnl2 1 - up 393 LN only necdin-like 2 0.000287 1.541378 0.50471 1.045895 TRM5 tRNA methyltransferase 5 homolog (S. 1452086_at 76357 Trmt5 1 - up 393 LN only cerevisiae) 0.004561 1.581031 0.69932 1.044634 RIKEN cDNA 1441970_at 399572 E430010N07R 1 - up 393 LN only E430010N07 gene 0.005433 1.572429 0.93327 1.042133

peptidylprolyl isomerase D (cyclophilin D) /// lysosomal- associated membrane protein 3 /// similar to peptidylprolyl 1417057_a_at 239739 // Ppid /// Lamp3 1 - up 393 LN only isomerase D 0.000279 1.693269 0.8232 1.041915 Ftsj homolog 1 (E. 1417099_at 54632 Ftsj1 1 - up 393 LN only coli) 0.00447 1.54456 0.72161 1.039288 signal-induced proliferation- 1434222_at 217692 Sipa1l1 1 - up 393 LN only associated 1 like 1 0.002742 2.446053 0.93155 1.037708 1455320_at ------1 - up 393 LN only --- 0.004537 1.840625 0.82851 1.037563 RIKEN cDNA 1456711_at 320214 4932425I24Rik1 - up 393 LN only 4932425I24 gene 0.000539 1.635342 0.69778 1.035915 RIKEN cDNA 1420329_at 76916 4930455C21Ri1 - up 393 LN only 4930455C21 gene 0.009053 1.527506 0.8616 1.034951

protein phosphatase 1A, magnesium dependent, alpha 1453171_s_at 19042 Ppm1a 1 - up 393 LN only isoform 0.007877 1.611279 0.80244 1.034844 1427278_at 78785 Rsnl2 1 - up 393 LN only restin-like 2 0.00704 4.297134 0.6959 1.03475 mitochondrial ribosomal protein 1450880_at 94063 Mrpl16 1 - up 393 LN only L16 0.003329 1.576979 0.86229 1.033268 cDNA sequence 1424587_at 237221 BC023488 1 - up 393 LN only BC023488 0.006151 1.60287 0.6415 1.030138 bromodomain containing 7 /// similar to bromodomain 1448521_at 26992 /// Brd7 /// LOC631 - up 393 LN only containing 7 0.007503 1.588157 0.70495 1.02958 fetal Alzheimer 1439102_at 207165 Falz 1 - up 393 LN only antigen 0.009701 1.666242 1 1.024633 cytochrome b5 type 1448844_at 66427 Cyb5b 1 - up 393 LN only B 0.002636 1.572783 0.7738 1.024269

solute carrier family 19 (sodium/hydrogen exchanger), member 1420138_at 20509 Slc19a1 1 - up 393 LN only 1 0.001562 2.031005 0.87999 1.022786 RAD52 homolog (S. 1416602_a_at 19365 Rad52 1 - up 393 LN only cerevisiae) 0.005827 1.552247 0.82808 1.019322

NADH dehydrogenase (ubiquinone) 1 beta 1458404_at 67264 Ndufb8 1 - up 393 LN only subcomplex 8 0.009239 1.667243 0.76242 1.017797

solute carrier family 19 (sodium/hydrogen exchanger), member 1448132_at 20509 Slc19a1 1 - up 393 LN only 1 0.006368 2.039751 0.955 1.015965 ribonuclease H2, 1452725_a_at 69724 Rnaseh2a 1 - up 393 LN only large subunit 0.000131 2.095551 0.91689 1.014603 mitochondrial ribosomal protein 1425189_a_at 27395 Mrpl15 1 - up 393 LN only L15 0.002705 1.654728 0.90953 1.013621 1452896_at 14894 Gtl3 1 - up 393 LN only gene trap locus 3 0.009828 1.603698 0.89622 1.010437 cyclin-dependent kinase (CDC2-like) 1433975_at 234854 Cdk10 1 - up 393 LN only 10 0.002514 1.523641 0.88461 1.009977 retinol 1418808_at 19682 Rdh5 1 - up 393 LN only dehydrogenase 5 0.001798 1.536942 0.84127 1.008872 RIKEN cDNA 1433962_at 328162 6720458F09Ri 1 - up 393 LN only 6720458F09 gene 0.000583 2.779474 0.68 1.007064 glycosyltransferase 28 domain 1418681_at 67574 Glt28d1 1 - up 393 LN only containing 1 0.001686 2.052385 0.94376 1.004169 1419462_s_at 14894 Gtl3 1 - up 393 LN only gene trap locus 3 0.000935 1.600528 1 1.002147 RNA binding motif 1436595_at 52202 Rbm34 1 - up 393 LN only protein 34 0.000998 1.728257 0.90905 1.00078 RIKEN cDNA 1452881_at 272551 4833427B12Ri 1 - up 393 LN only 4833427B12 gene 0.00781 1.621258 0.79454 0.998367

regulating synaptic membrane 1450761_s_at 116838 Rims2 1 - up 393 LN only exocytosis 2 0.004823 1.622854 0.93224 0.998261 leucine rich repeat 1437471_at 217366 Lrrc45 1 - up 393 LN only containing 45 0.006382 1.520997 0.96281 0.997338 protein kinase, cAMP dependent regulatory, type II 1456475_s_at 19088 Prkar2b 1 - up 393 LN only beta 0.000821 3.232492 0.93183 0.997118 1452852_at 28071 Twistnb 1 - up 393 LN only TWIST neighbor 0.00384 1.669491 0.92962 0.995061

protein phosphatase 1A, magnesium dependent, alpha 1429501_s_at 19042 Ppm1a 1 - up 393 LN only isoform 0.003611 1.877313 0.96961 0.992421 elaC homolog 2 (E. 1428477_at 68626 Elac2 1 - up 393 LN only coli) 0.009521 1.506867 0.98568 0.990634 RIKEN cDNA 1433672_at 215201 4732479N06Ri1 - up 393 LN only 4732479N06 gene 0.003572 1.596924 0.95458 0.988172 1424915_s_at ------1 - up 393 LN only --- 0.004684 1.618511 0.97158 0.987465 mutL homolog 3 (E 1426052_at 217716 Mlh3 1 - up 393 LN only coli) 0.004369 1.515907 0.91439 0.98743 TNF receptor- 1416170_at 68015 Trap1 1 - up 393 LN only associated protein 1 0.00163 1.69693 0.80643 0.987283 tripartite motif 1434554_at 68729 Trim37 1 - up 393 LN only protein 37 0.007328 1.630271 0.67362 0.985076

spermine synthase /// similar to Spermine synthase (Spermidine aminopropyltransfera 1421052_a_at 20603 /// Sms /// LOC67 1 - up 393 LN only se) (SPMSY) 0.00435 1.719062 0.90711 0.982459

solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to solute carrier 1430542_a_at 11740 /// Slc25a5 /// LOC1 - up 393 LN only family 25, member 5 0.005575 1.679567 0.75747 0.977342 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to solute carrier family 25, member 5 /// similar to ADP/ATP translocase 2 (Adenine nucleotide translocator 2) (ANT 2) (ADP,ATP carrier protein 2) (Solute carrier family 25 member 5) /// similar to solute carrier family 25, member 5 /// similar to ADP/ATP translocase 2 (Adenine nucleotide 1438545_at 11740 /// Slc25a5 /// LOC1 - up 393 LN only translocator 2) (ANT 0.00508 1.789213 0.75571 0.976559

general transcription factor IIF, 1426626_at 68705 Gtf2f2 1 - up 393 LN only polypeptide 2 0.002049 1.502407 0.72152 0.974906 Ngg1 interacting factor 3-like 1 (S. 1438728_at 65102 Nif3l1 1 - up 393 LN only pombe) 0.00542 1.654768 0.79425 0.968015 kelch domain 1424887_at 234825 Klhdc4 1 - up 393 LN only containing 4 0.002336 1.730693 0.67635 0.967401

pescadillo homolog 1, containing BRCT 1416172_at 64934 Pes1 1 - up 393 LN only domain (zebrafish) 0.002641 1.503685 0.66501 0.967171 brix domain 1421945_a_at 67239 Bxdc1 1 - up 393 LN only containing 1 0.002473 1.729397 0.65194 0.963596 methionine aminopeptidase-like 1452464_a_at 66559 Metapl1 1 - up 393 LN only 1 0.001307 1.77342 0.51102 0.961897

forty-two-three 1451325_at 69823 Fyttd1 1 - up 393 LN only domain containing 1 8.76E-05 1.882993 0.67522 0.959202 phosphoribosyl pyrophosphate 1454843_at 110639 Prps2 1 - up 393 LN only synthetase 2 0.000848 2.033808 0.72856 0.951658 positive cofactor 2, multiprotein complex, glutamine/Q-rich- 1444688_at 94112 Pcqap 1 - up 393 LN only associated protein 0.001238 1.678277 0.69056 0.951523 proteosome (prosome, macropain) 26S subunit, non- 1436559_a_at 53380 Psmd10 1 - up 393 LN only ATPase, 10 0.005129 1.586112 0.72725 0.947546 dihydrouridine synthase 4-like (S. 1453252_at 71916 Dus4l 1 - up 393 LN only cerevisiae) 0.003366 2.449501 0.66013 0.947481

polymerase (DNA- directed), delta 1422732_at 67811 Poldip2 1 - up 393 LN only interacting protein 2 0.007688 1.587747 0.51055 0.946512 RIKEN cDNA 1434981_at 102124 E130303B06R 1 - up 393 LN only E130303B06 gene 0.000141 1.649144 0.42819 0.946414

clusterin associated 1424388_at 76779 Cluap1 1 - up 393 LN only protein 1 0.002437 1.795055 0.37083 0.943438 RIKEN cDNA 1453433_at 72338 2600001A11Ri 1 - up 393 LN only 2600001A11 gene 0.000746 1.832528 0.47138 0.940293 placental specific 1417553_at 56096 Plac1 1 - up 393 LN only protein 1 0.000186 2.643129 0.50814 0.937638 tripartite motif- 1436829_at 330863 Trim67 1 - up 393 LN only containing 67 0.009802 2.375871 0.9904 0.937302 DNA segment, Chr 10, Wayne State University 52, 1423880_at 28088 D10Wsu52e 1 - up 393 LN only expressed 0.003342 1.534628 0.37213 0.937268 RIKEN cDNA 1300013D18 gene /// similar to cytochrome P450, family 2, subfamily d, 1430814_at 271300 // 1300013D18Ri1 - up 393 LN only polypeptide 13 0.008444 4.620787 0.90901 0.934457 RIKEN cDNA 1453324_at 76155 6330509M23R 1 - up 393 LN only 6330509M23 gene 0.007512 1.569963 0.65967 0.932425

N-acetyltransferase ARD1 homolog (S. 1417118_a_at 56292 Ard1 1 - up 393 LN only cerevisiae) 0.005363 1.636885 0.51364 0.930569 plasmacytoma variant translocation 1450541_at 19296 Pvt1 1 - up 393 LN only 1 0.002897 3.585973 0.44796 0.930044

methyltransferase 5 1428900_s_at 76894 Mett5d1 1 - up 393 LN only domain containing 1 0.00329 1.553995 0.20867 0.929084

mitochondrial 1418034_at 69527 Mrps9 1 - up 393 LN only ribosomal protein S9 0.00439 1.51271 0.60146 0.929062 XRCC6 binding 1453380_a_at 68876 Xrcc6bp1 1 - up 393 LN only protein 1 0.002161 1.846274 0.47923 0.928541 Down syndrome critical region 1448307_at 56088 Dscr2 1 - up 393 LN only homolog 2 (human) 0.002427 1.795112 0.34792 0.926865 dynein light chain 1420614_at 67117 Dynlt3 1 - up 393 LN only Tctex-type 3 0.00742 1.691863 0.43426 0.926154 methyltransferase 1451141_at 228019 Mettl8 1 - up 393 LN only like 8 0.006313 1.72638 0.38189 0.925924 coenzyme Q9 1428134_at 67914 Coq9 1 - up 393 LN only homolog (yeast) 0.00062 1.654442 0.22874 0.922136

Mki67 (FHA domain) interacting nucleolar 1424001_at 67949 Mki67ip 1 - up 393 LN only phosphoprotein 0.0013 1.595622 0.34723 0.921648

translocase of inner mitochondrial membrane 8 1416345_at 30058 Timm8a1 1 - up 393 LN only homolog a1 (yeast) 0.000614 2.225898 0.59625 0.918995 RRS1 ribosome biogenesis regulator homolog (S. 1456865_x_at 59014 Rrs1 1 - up 393 LN only cerevisiae) 0.001691 1.546668 0.20247 0.917604

methylmalonic aciduria (cobalamin 1417857_at 109136 Mmaa 1 - up 393 LN only deficiency) type A 0.008038 1.636836 0.42572 0.917521

histone deacetylase 6 /// similar to Histone deacetylase 6 (HD6) (Histone deacetylase 1448928_at 15185 /// Hdac6 /// LOC61 - up 393 LN only mHDA2) 0.001313 1.551922 0.45154 0.91497

TNF receptor- 1437379_x_at 68015 Trap1 1 - up 393 LN only associated protein 1 0.001246 1.725639 0.41272 0.913414 1417454_at 72584 Cul4b 1 - up 393 LN only cullin 4B 0.001263 1.541213 0.35325 0.909663 LSM6 homolog, U6 small nuclear RNA associated (S. 1437108_at 78651 Lsm6 1 - up 393 LN only cerevisiae) 0.009288 1.746028 0.51605 0.906755 RIKEN cDNA 1454878_at 224170 2310047C04Ri1 - up 393 LN only 2310047C04 gene 0.000513 1.702482 0.40914 0.903504

cirrhosis, autosomal recessive 1A 1423884_at 21771 Cirh1a 1 - up 393 LN only (human) 0.002125 1.6076 0.40024 0.899783

spastic paraplegia 1428260_at 73991 Spg3a 1 - up 393 LN only 3A homolog (human) 0.00325 1.609324 0.49218 0.899618

L-2-hydroxyglutarate 1424858_at 217666 L2hgdh 1 - up 393 LN only dehydrogenase 0.003343 1.799908 0.17288 0.89673 carbonic anhydrase 1419705_at 56078 Car5b 1 - up 393 LN only 5b, mitochondrial 0.001078 1.574119 0.12453 0.89154

protein phosphatase 1, regulatory (inhibitor) subunit 1430286_s_at 76142 Ppp1r14c 1 - up 393 LN only 14c 0.009692 1.739527 0.35769 0.890957 RIKEN cDNA 1417779_at 66566 2310079N02Ri1 - up 393 LN only 2310079N02 gene 0.00132 1.843214 0.39166 0.889562 1448677_at 18117 Cox4nb 1 - up 393 LN only COX4 neighbor 0.000329 1.546151 0.20434 0.88927 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1, related 1455727_at 22184 U2af1-rs2 1 - up 393 LN only sequence 2 0.000238 1.857177 0.10549 0.889084 mitochondrial ribosomal protein 1433878_at 99045 Mrps26 1 - up 393 LN only S26 0.00335 1.577877 0.22513 0.887814 protein kinase, cAMP dependent regulatory, type II 1438664_at 19088 Prkar2b 1 - up 393 LN only beta 0.000325 3.381426 0.56439 0.885742 RIKEN cDNA 1430614_at 74347 4632415K11Ri 1 - up 393 LN only 4632415K11 gene 0.003579 1.937589 0.51405 0.884065 staufen (RNA binding protein) homolog 2 1450916_at 29819 Stau2 1 - up 393 LN only (Drosophila) 0.000634 2.397311 0.40476 0.882394 polymerase (RNA) II (DNA directed) 1416341_at 20021 Polr2c 1 - up 393 LN only polypeptide C 0.000624 1.602967 0.35559 0.881242 RIKEN cDNA 1428798_s_at 66083 0610039J04Rik1 - up 393 LN only 0610039J04 gene 0.009532 1.962793 0.32753 0.8767 RIKEN cDNA 1428775_at 66132 1110008L16Ri 1 - up 393 LN only 1110008L16 gene 0.008356 2.262485 0.48258 0.874375

growth arrest and DNA-damage- inducible, gamma 1417619_at 102060 Gadd45gip1 1 - up 393 LN only interacting protein 1 0.000626 2.107421 0.2429 0.866457 RIKEN cDNA 1428797_at 66083 0610039J04Rik1 - up 393 LN only 0610039J04 gene 0.009828 1.841172 0.31172 0.864532

guanine nucleotide binding protein (G protein), beta 1419316_s_at 13972 Gnb1l 1 - up 393 LN only polypeptide 1-like 0.001901 1.887631 0.29982 0.860537 RIKEN cDNA 1440204_at 67293 3110039M20R 1 - up 393 LN only 3110039M20 gene 1.66E-06 19.76783 0.23363 0.855998

ankyrin repeat and SOCS box- 1449459_s_at 142688 Asb13 1 - up 393 LN only containing protein 13 0.007342 2.021913 0.25386 0.854799 RRS1 ribosome biogenesis regulator homolog (S. 1416998_at 59014 Rrs1 1 - up 393 LN only cerevisiae) 0.004448 1.707921 0.15835 0.846994 RIKEN cDNA 1426669_at 223978 C530044N13R 1 - up 393 LN only C530044N13 gene 0.006511 1.68547 0.21855 0.835603 solute carrier family 14 (urea transporter), member 1428114_at 108052 Slc14a1 1 - up 393 LN only 1 0.000586 15.70186 0.98611 0.832058

Acyl-CoA synthetase long-chain family 1437031_at 216739 Acsl6 1 - up 393 LN only member 6 3.96E-05 5.863303 0.38762 0.824044 carbonic anhydrase 1448752_at 12349 Car2 1 - up 393 LN only 2 0.005035 3.082913 0.47831 0.817351 1447854_s_at 319190 Hist2h2be 1 - up 393 LN only histone 2, H2be 0.006761 2.547553 0.13709 0.772252 1424890_at 12173 Bnc1 1 - up 393 LN only basonuclin 1 0.007509 3.743738 0.57688 0.729806 RIKEN cDNA 1428550_at 69101 1810015A11Ri 1 - up 393 LN only 1810015A11 gene 0.006259 3.029227 0.10142 0.70781 hydroxypyruvate isomerase homolog 1425201_a_at 68180 Hyi 2 - down 393 LN only (E. coli) 2.77E-05 0.484959 0.02408 1.269279 1426074_at 434536 LOC434536 2 - down 393 LN only LOC434536 0.001627 0.492143 0.48805 1.266088 FMS-like tyrosine 1419300_at 14254 Flt1 2 - down 393 LN only kinase 1 0.009102 0.500249 0.25259 1.257721 epoxide hydrolase 2, 1448499_a_at 13850 Ephx2 2 - down 393 LN only cytoplasmic 0.000498 0.377215 0.93242 1.251467

activating 1425927_a_at 107503 Atf5 2 - down 393 LN only transcription factor 5 0.008753 0.644791 0.57593 1.244768 RIKEN cDNA 4930406H16 gene /// NACHT, leucine rich repeat and PYD 1457179_at 446099 // 4930406H16Ri2 - down 393 LN only containing 4E 0.005362 0.22573 0.46297 1.237828 1416203_at 11826 Aqp1 2 - down 393 LN only aquaporin 1 0.002401 0.306271 0.47334 1.229574 DNA segment, Chr 2, ERATO Doi 173, 1444330_at 51864 D2Ertd173e 2 - down 393 LN only expressed 0.008146 0.60054 0.27558 1.205155 RIKEN cDNA 1431486_at 75030 4930503E24Ri 2 - down 393 LN only 4930503E24 gene 0.003924 0.426969 0.11696 1.19342 RIKEN cDNA 1438074_at 70080 2210010C17Ri2 - down 393 LN only 2210010C17 gene 5.13E-05 0.61462 0.01374 1.189708 RIKEN cDNA 1430122_at 77265 9430002A10Ri 2 - down 393 LN only 9430002A10 gene 0.009511 0.576192 0.36109 1.181315 RIKEN cDNA 1445654_at 71640 4930422I07Rik2 - down 393 LN only 4930422I07 gene 0.007138 0.649725 0.47226 1.177946 RNA binding motif protein, X 1416354_at 19655 Rbmx 2 - down 393 LN only chromosome 0.006611 0.581837 0.25337 1.150543

ST8 alpha-N-acetyl- neuraminide alpha- 2,8-sialyltransferase 1442929_at 225742 St8sia5 2 - down 393 LN only 5 0.003364 0.380549 0.80751 1.129271 v-myc myelocytomatosis viral related oncogene, neuroblastoma 1417155_at 18109 Mycn 2 - down 393 LN only derived (avian) 0.000204 0.227176 0.74912 1.115583

RIKEN cDNA C030014M07 gene /// similar to RIKEN 1435123_at 320843 // C030014M07R2 - down 393 LN only cDNA C920006C10 0.008417 0.427472 0.58244 1.114796

ATP-binding cassette, sub-family 1416679_at 19299 Abcd3 2 - down 393 LN only D (ALD), member 3 0.00013 0.617217 0.11306 1.107437

ATPase, aminophospholipid transporter (APLT), class I, type 8A, 1454728_s_at 11980 Atp8a1 2 - down 393 LN only member 1 0.000209 0.467329 0.51708 1.099418

polypyrimidine tract 1423470_at 56195 Ptbp2 2 - down 393 LN only binding protein 2 0.002903 0.59639 0.38597 1.093755

ATPase, aminophospholipid transporter (APLT), class I, type 8A, 1433827_at 11980 Atp8a1 2 - down 393 LN only member 1 0.000591 0.502869 0.76922 1.093377 ankyrin repeat 1436538_at 654824 Ankrd37 2 - down 393 LN only domain 37 0.000565 0.631002 0.81666 1.089098 zinc finger and BTB domain containing 1436365_at 207259 Zbtb7c 2 - down 393 LN only 7C 0.002826 0.654149 0.2302 1.078021

RAS-like, estrogen- regulated, growth- 1451236_at 232441 Rerg 2 - down 393 LN only inhibitor 0.008932 0.545277 0.86014 1.076624 RIKEN cDNA 1442916_at 234353 4931420C21Ri2 - down 393 LN only 4931420C21 gene 0.000501 0.618597 0.62405 1.071608

neurotrophin receptor associated 1429127_at 67169 Nradd 2 - down 393 LN only death domain 0.008646 0.477443 0.54884 1.068354 open reading frame 1451810_at 224419 ORF63 2 - down 393 LN only 63 0.002621 0.639522 0.79147 1.066353 rhophilin, Rho GTPase binding 1434628_a_at 52428 Rhpn2 2 - down 393 LN only protein 2 0.002779 0.49875 0.89839 1.062375 RIKEN cDNA 1428663_at 71305 5133401H06Ri2 - down 393 LN only 5133401H06 gene 0.008237 0.472194 0.86764 1.04935

solute carrier family 1429154_at 72022 Slc35f2 2 - down 393 LN only 35, member F2 0.002445 0.493869 0.84104 1.038134 IQ motif containing GTPase activating 1433885_at 544963 Iqgap2 2 - down 393 LN only protein 2 0.001937 0.453094 0.89287 1.031786 acyl-CoA 1429267_at 329910 Acot11 2 - down 393 LN only thioesterase 11 0.006553 0.65245 0.77796 1.024001 UDP-glucose 1447411_at 22235 Ugdh 2 - down 393 LN only dehydrogenase 0.003371 0.646475 0.78711 1.021377

abhydrolase domain 1419104_at 66082 Abhd6 2 - down 393 LN only containing 6 0.006757 0.613316 0.93613 1.018498

1433532_a_at 17196 Mbp 2 - down 393 LN only myelin basic protein 7.99E-06 0.407292 0.94302 1.015491

guanine nucleotide binding protein, 1434440_at 14677 Gnai1 2 - down 393 LN only alpha inhibiting 1 0.00173 0.664068 1 1.014203 OCIA domain 1453187_at 433904 Ociad2 2 - down 393 LN only containing 2 0.000541 0.649398 0.9785 1.000429

ATPase, aminophospholipid transporter (APLT), class I, type 8A, 1423597_at 11980 Atp8a1 2 - down 393 LN only member 1 0.00011 0.596643 0.90612 0.995024

sorbin and SH3 1437197_at 234214 Sorbs2 2 - down 393 LN only domain containing 2 0.003729 0.578369 0.90067 0.988084

12 days embryo spinal ganglion cDNA, RIKEN full- length enriched library, clone:D130076B20 product:unclassifiabl e, full insert 1446555_at ------2 - down 393 LN only sequence 0.009647 0.632112 0.92785 0.987685 cDNA sequence 1443827_x_at 80752 BC004044 2 - down 393 LN only BC004044 0.004136 0.364046 0.79557 0.98764 rhophilin, Rho GTPase binding 1431805_a_at 52428 Rhpn2 2 - down 393 LN only protein 2 0.005032 0.50058 0.80823 0.983568 Zinc finger, CCHC domain containing 1456668_at 230594 Zcchc11 2 - down 393 LN only 11 0.002857 0.591168 0.80122 0.982403 1442201_at ------2 - down 393 LN only Transcribed locus 0.006091 0.659582 0.82689 0.981411 1452679_at 73710 Tubb2b 2 - down 393 LN only tubulin, beta 2b 0.007867 0.563093 0.82205 0.978163 1444052_at ------2 - down 393 LN only Transcribed locus 0.003857 0.531137 0.752 0.976903 1430912_a_at 21684 Tectb 2 - down 393 LN only tectorin beta 0.003169 0.643843 0.75819 0.976254 RIKEN cDNA 1441545_at 320841 9230115F04Ri 2 - down 393 LN only 9230115F04 gene 0.00149 0.660152 0.56475 0.973927 1446867_at ------2 - down 393 LN only --- 0.007204 0.550279 0.72688 0.966719 nucleosome assembly protein 1- 1417411_at 58243 Nap1l5 2 - down 393 LN only like 5 0.001052 0.238187 0.63613 0.965143 zinc finger, CCHC domain containing 1437395_at 230594 Zcchc11 2 - down 393 LN only 11 0.000628 0.607026 0.62769 0.96467 Slit homolog 2 1447056_at 20563 Slit2 2 - down 393 LN only (Drosophila) 0.002686 0.660612 0.68594 0.96377 Adult male medulla oblongata cDNA, RIKEN full-length enriched library, clone:6330445K22 product:unclassifiabl e, full insert 1436139_at ------2 - down 393 LN only sequence 0.007925 0.560767 0.64224 0.960791 Zinc finger protein 1441324_at 380912 Zfp395 2 - down 393 LN only 395 0.005453 0.642732 0.74551 0.955687 Cysteine rich transmembrane BMP regulator 1 1459632_at 50766 Crim1 2 - down 393 LN only (chordin like) 0.000248 0.632165 0.58908 0.952605 similar to T-cell receptor alpha chain V region CTL-F3 1441286_at 328483 LOC328483 2 - down 393 LN only precursor 0.006783 0.539323 0.61915 0.951178 cDNA sequence 1417688_at 80752 BC004044 2 - down 393 LN only BC004044 0.000349 0.438992 0.48858 0.943351 cDNA sequence 1457648_x_at 80752 BC004044 2 - down 393 LN only BC004044 0.002259 0.358328 0.75 0.943336 Membrane- associated ring 1457154_at 223455 39513 2 - down 393 LN only finger (C3HC4) 6 0.00287 0.603043 0.60029 0.937641

glutamate receptor, 1459245_s_at 14804 Grid2 2 - down 393 LN only ionotropic, delta 2 0.007367 0.349308 0.76598 0.932018 calcium/calmodulin- dependent protein 1456609_at 66259 Camk2n1 2 - down 393 LN only kinase II inhibitor 1 0.008815 0.409087 0.18935 0.931367 1438939_x_at 17984 Ndn 2 - down 393 LN only necdin 0.009412 0.663361 0.58629 0.925702 oxidation resistance 1418501_a_at 170719 Oxr1 2 - down 393 LN only 1 0.001312 0.636731 0.19438 0.923732 RIKEN cDNA 1454153_at 75342 4930556J24Rik2 - down 393 LN only 4930556J24 gene 0.007777 0.619292 0.46017 0.920559

expressed sequence 1440455_at 100222 AI848599 2 - down 393 LN only AI848599 0.001212 0.58345 0.16037 0.919564

ATPase, Na+/K+ transporting, alpha 1 1435919_at 11928 Atp1a1 2 - down 393 LN only polypeptide 0.003783 0.413273 0.61808 0.909976

ATP-binding cassette, sub-family B (MDR/TAP), 1418872_at 18669 Abcb1b 2 - down 393 LN only member 1B 0.008971 0.489768 0.5059 0.907966 RAB36, member RAS oncogene 1431136_at 76877 Rab36 2 - down 393 LN only family 0.002082 0.493951 0.52249 0.907872 procollagen C- endopeptidase 1437165_a_at 18542 Pcolce 2 - down 393 LN only enhancer protein 0.002324 0.612688 0.51654 0.907648

N-myc downstream 1456174_x_at 17988 Ndrg1 2 - down 393 LN only regulated gene 1 0.006474 0.636112 0.5086 0.903222 WT1-interacting 1433651_at 101543 Wtip 2 - down 393 LN only protein 0.00077 0.269755 0.46501 0.902308 paraneoplastic 1435618_at 239157 Pnma2 2 - down 393 LN only antigen MA2 0.002092 0.581789 0.28501 0.886074 Arginine/serine-rich 1441267_at 66880 Rsrc1 2 - down 393 LN only coiled-coil 1 0.00639 0.375429 0.54885 0.885322

0 day neonate lung cDNA, RIKEN full- length enriched library, clone:E030034L15 product:unclassifiabl e, full insert 1443137_at ------2 - down 393 LN only sequence 0.001537 0.634599 0.24766 0.884915

fat tumor suppressor homolog (Drosophila) /// similar to fat tumor 1433857_at 14107 /// Fath /// LOC67 2 - down 393 LN only suppressor homolog 8.19E-05 0.516439 0.15492 0.882791

decay accelerating 1427632_x_at 13137 Daf2 2 - down 393 LN only factor 2 0.006897 0.441459 0.4732 0.881189 similar to zinc finger protein of the 1425666_at 624168 LOC624168 2 - down 393 LN only cerebellum 5 0.002752 0.623937 0.25154 0.879189 RIKEN cDNA 1444703_at 69964 2810403D21Ri2 - down 393 LN only 2810403D21 gene 0.007601 0.651821 0.45121 0.874903 epidermal growth factor receptor pathway substrate 1419251_at 13858 Eps15 2 - down 393 LN only 15 0.007837 0.614094 0.28406 0.874371 membrane- associated ring 1430994_at 69104 39512 2 - down 393 LN only finger (C3HC4) 5 0.008689 0.660228 0.20004 0.870804 centromere protein 1453659_at 52504 Cenpo 2 - down 393 LN only O 0.00338 0.612248 0.37089 0.867671 1449728_at ------2 - down 393 LN only Transcribed locus 0.005457 0.496456 0.39223 0.859264 phosphodiesterase 1458499_at 23984 Pde10a 2 - down 393 LN only 10A 0.008229 0.652158 0.17853 0.858522 RIKEN cDNA 1428922_at 66873 1200009O22R 2 - down 393 LN only 1200009O22 gene 6.37E-05 0.663378 0.22336 0.857459 1423551_at 12554 Cdh13 2 - down 393 LN only cadherin 13 5.27E-05 0.284469 0.38271 0.855223 IQ motif containing GTPase activating 1459894_at 544963 Iqgap2 2 - down 393 LN only protein 2 0.003718 0.460859 0.44737 0.851416 1434115_at ------2 - down 393 LN only --- 3.85E-06 0.258765 0.29481 0.850866 small proline-rich 1449133_at 20753 Sprr1a 2 - down 393 LN only protein 1A 0.000663 0.409912 0.14797 0.850767 oxidation resistance 1418502_a_at 170719 Oxr1 2 - down 393 LN only 1 0.000989 0.637268 0.06004 0.847062 1415854_at 17311 Kitl 2 - down 393 LN only kit ligand 0.001496 0.618684 0.02322 0.845691 RIKEN cDNA 1443328_at 78757 4921505C17Ri2 - down 393 LN only 4921505C17 gene 0.00298 0.565829 0.28504 0.844323 1446964_at ------2 - down 393 LN only --- 0.00497 0.595056 0.3012 0.843437 GTP cyclohydrolase 1420499_at 14528 Gch1 2 - down 393 LN only 1 0.000227 0.614098 0.25005 0.843364 TatD DNase domain 1458679_a_at 69694 Tatdn1 2 - down 393 LN only containing 1 0.002111 0.600417 0.04415 0.836937

expressed sequence 1448075_at 103079 AA408251 2 - down 393 LN only AA408251 0.00528 0.535983 0.18441 0.834691

Arginine-tRNA- 1446611_at 11907 Ate1 2 - down 393 LN only protein transferase 1 0.003164 0.557235 0.16239 0.830493 RIKEN cDNA 1447110_at 223989 4921513D23Ri2 - down 393 LN only 4921513D23 gene 0.006585 0.651169 0.2279 0.82881 metallophosphoester ase domain 1433701_at 223726 Mpped1 2 - down 393 LN only containing 1 0.001388 0.633723 0.09875 0.828341 RIKEN cDNA 1453775_at 78757 4921505C17Ri2 - down 393 LN only 4921505C17 gene 0.000244 0.530835 0.10801 0.823583 fragile histidine triad 1425893_a_at 14198 Fhit 2 - down 393 LN only gene 0.005873 0.543123 0.23096 0.81826 tryptophan 1419524_at 21990 Tph1 2 - down 393 LN only hydroxylase 1 0.001718 0.425488 0.24736 0.806249 Zinc finger, CCHC domain containing 1456553_at 230594 Zcchc11 2 - down 393 LN only 11 0.007276 0.610247 0.169 0.804263 dual specificity 1448830_at 19252 Dusp1 2 - down 393 LN only phosphatase 1 0.003488 0.49175 0.09076 0.799448 slit homolog 2 1458140_at 20563 Slit2 2 - down 393 LN only (Drosophila) 0.002938 0.556686 0.26446 0.796794 glia maturation 1448571_a_at 63985 Gmfb 2 - down 393 LN only factor, beta 0.001685 0.588023 0.16521 0.796127 zinc finger protein 1425010_at 104349 Zfp119 2 - down 393 LN only 119 0.001511 0.500383 0.14043 0.781921 RIKEN cDNA 1441359_at 320841 9230115F04Ri 2 - down 393 LN only 9230115F04 gene 0.001726 0.547159 0.06445 0.777332 similar to melanoma 1455038_at 632764 LOC632764 2 - down 393 LN only antigen 0.00376 0.326686 0.25232 0.765332 Slit homolog 2 1440650_at 20563 Slit2 2 - down 393 LN only (Drosophila) 0.008102 0.362147 0.33073 0.759874

1443464_at 20649 Sntb1 2 - down 393 LN only Syntrophin, basic 1 0.000958 0.381994 0.21368 0.734376 chemokine (C-C 1419413_at 20295 Ccl17 2 - down 393 LN only motif) ligand 17 0.00025 0.411045 0.13462 0.726199

solute carrier family 9 (sodium/hydrogen exchanger), member 1442915_at 110895 Slc9a4 2 - down 393 LN only 4 0.008332 0.394292 0.21643 0.717785 1449892_at 67328 Lyzl1 2 - down 393 LN only lysozyme-like 1 0.00262 0.145513 0.48856 0.713015 RIKEN cDNA 1453880_s_at 73332 1700041C02Ri2 - down 393 LN only 1700041C02 gene 0.008879 0.48144 0.10317 0.701935 cDNA sequence 1434202_a_at 268709 BC055107 2 - down 393 LN only BC055107 0.003684 0.412029 0.08819 0.696314 WD repeat domain 1436675_at 242253 Wdr63 2 - down 393 LN only 63 0.006162 0.245698 0.1993 0.635713 1455593_at 238055 Apob 3 - up 344 SQ only apolipoprotein B 0.642089 2.764437 1.3E-06 134.9865

V-set and immunoglobulin 1430553_at 78789 Vsig1 3 - up 344 SQ only domain containing 1 0.751252 4.008449 5.2E-07 57.18844 1418213_at 94179 Krt23 3 - up 344 SQ only keratin 23 0.027816 9.746013 9.2E-06 52.67882

surfactant 1437028_at 20388 Sftpb 3 - up 344 SQ only associated protein B 0.462624 0.940961 3.1E-05 46.28937

gap junction membrane channel 1439793_at 14611 Gja3 3 - up 344 SQ only protein alpha 3 0.645575 1.344725 0.00233 37.13026 S100 calcium 1448964_at 12309 S100g 3 - up 344 SQ only binding protein G 0.845564 0.804878 0.00306 35.43042 1422833_at 15376 Foxa2 3 - up 344 SQ only forkhead box A2 0.130633 2.893783 5E-08 34.6525

small nuclear 1435716_x_at 20646 Snrpn 3 - up 344 SQ only ribonucleoprotein N 0.375747 1.696837 0.00015 26.27504 PR domain 1440870_at 70673 Prdm16 3 - up 344 SQ only containing 16 0.028509 4.028507 3.7E-07 24.45001

chloride intracellular 1454866_s_at 209195 Clic6 3 - up 344 SQ only channel 6 0.320811 3.970048 0.0006 22.52019 1458492_x_at 235106 Hnt 3 - up 344 SQ only neurotrimin 0.821957 0.810643 0.00058 22.17828 gene model 131, (NCBI) /// similar to 1457271_at 229697 // Gm131 /// LOC3 - up 344 SQ only prochymosin 0.820619 1.063259 0.00488 21.93433 cytochrome P450, family 4, subfamily f, 1419559_at 64385 Cyp4f14 3 - up 344 SQ only polypeptide 14 0.778149 1.038801 0.00239 19.98118 1419148_at 11567 Avil 3 - up 344 SQ only advillin 0.313822 0.917768 5.6E-05 17.32179 1449244_at 12558 Cdh2 3 - up 344 SQ only cadherin 2 0.166515 1.32407 0.00028 16.44649

autism susceptibility 1457139_at 319974 Auts2 3 - up 344 SQ only candidate 2 0.520548 1.089041 4.1E-08 16.2564 1430443_at 26359 Anxa10 3 - up 344 SQ only annexin A10 0.290864 0.773003 5.1E-05 16.10307 1454604_s_at 269831 Tspan12 3 - up 344 SQ only tetraspanin 12 0.124828 2.293834 1.2E-06 14.80531 1418815_at 12558 Cdh2 3 - up 344 SQ only cadherin 2 0.925671 0.991715 0.00072 14.55796

neural cell adhesion 1426864_a_at 17967 Ncam1 3 - up 344 SQ only molecule 1 0.236919 2.479616 0.00024 14.44978

10 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:B930049N01 product:unclassifiabl e, full insert 1442873_at ------3 - up 344 SQ only sequence 0.635368 0.844863 0.00126 14.36979

chloride intracellular 1456873_at 224796 Clic5 3 - up 344 SQ only channel 5 0.051118 1.417554 0.00155 14.24106 1428393_at 68404 Nrn1 3 - up 344 SQ only neuritin 1 0.207243 2.44319 2.4E-05 13.57047 1447096_at ------3 - up 344 SQ only Transcribed locus 0.137548 0.783803 7.8E-06 12.73283

autism susceptibility 1427293_a_at 319974 Auts2 3 - up 344 SQ only candidate 2 0.095581 0.792726 3E-06 12.47832 zinc finger protein 1417849_at 170753 Zfp704 3 - up 344 SQ only 704 0.574825 1.69049 0.00017 12.41657 1439231_at ------3 - up 344 SQ only --- 0.914779 0.973859 0.00014 11.68807 1426282_at 235106 Hnt 3 - up 344 SQ only neurotrimin 0.011115 1.511807 0.00103 11.42386 monoamine oxidase 1434354_at 109731 Maob 3 - up 344 SQ only B 0.08783 1.271385 0.00016 11.23269 similar to Tetraspanin-15 (Tspan-15) (Transmembrane 4 superfamily member 15) (Tetraspan NET- 1424653_at 669875 LOC669875 3 - up 344 SQ only 7) 0.684562 1.229211 0.00045 10.94604 zinc finger 1437556_at 80892 Zfhx4 3 - up 344 SQ only homeodomain 4 0.076701 2.904118 9.6E-07 10.90063 transmembrane 1457701_at 235300 Tmem136 3 - up 344 SQ only protein 136 0.314763 1.44 0.00016 10.6952 gene model 98, 1439506_at 225908 Gm98 3 - up 344 SQ only (NCBI) 0.785663 1.712496 4.3E-05 10.53606

deleted in malignant 1418287_a_at 12945 Dmbt1 3 - up 344 SQ only brain tumors 1 0.479218 0.484287 0.00553 10.22182 fucosyltransferase 1454924_at 171167 Fut10 3 - up 344 SQ only 10 0.413366 1.527873 0.00534 10.07247 RIKEN cDNA 1433167_at 74874 4930444E06Ri 3 - up 344 SQ only 4930444E06 gene 0.9205 1.001611 0.00069 9.918367 Kruppel-like factor 1455521_at 16597 Klf12 3 - up 344 SQ only 12 0.479582 1.803079 0.00029 9.884962

insulin promoter factor 1, homeodomain 1422174_at 18609 Ipf1 3 - up 344 SQ only transcription factor 0.295559 1.967308 0.00041 9.495908 calcium/calmodulin- dependent protein 1460630_at 108058 Camk2d 3 - up 344 SQ only kinase II, delta 0.067475 2.341672 0.0002 9.483667 ankyrin repeat and sterile alpha motif domain containing 1B /// similar to AIDA- 1452938_at 544718 // Anks1b /// LOC3 - up 344 SQ only 1b 0.582518 1.542884 0.00052 9.425992 LIM-domain containing, protein 1456234_at 16885 Limk1 3 - up 344 SQ only kinase 0.200185 2.860789 0.0002 9.320186

phospholipase A2, 1437015_x_at 18778 Pla2g1b 3 - up 344 SQ only group IB, pancreas 0.424686 1.184053 0.00106 9.251815 zinc finger 1421433_at 80892 Zfhx4 3 - up 344 SQ only homeodomain 4 0.080567 2.575711 6.2E-05 8.940418 1426283_at 235106 Hnt 3 - up 344 SQ only neurotrimin 0.459677 0.837153 0.0004 8.922304 RIKEN cDNA 1438989_s_at 320860 B130021B11R 3 - up 344 SQ only B130021B11 gene 0.514695 1.951651 0.00146 8.395827 ADP-ribosylation 1430234_at 71619 Arl14 3 - up 344 SQ only factor-like 14 0.304681 0.823859 5.8E-06 8.329092

gap junction membrane channel 1449204_at 14622 Gjb5 3 - up 344 SQ only protein beta 5 0.156852 1.497616 0.00202 8.258085 1417497_at 12870 Cp 3 - up 344 SQ only ceruloplasmin 0.188407 1.292094 0.0001 8.027283 carbonic anhydrase 1427013_at 230099 Car9 3 - up 344 SQ only 9 0.475217 1.21313 1.7E-05 8.004467 neural cell adhesion 1439556_at 17967 Ncam1 3 - up 344 SQ only molecule 1 0.345455 1.58493 0.00016 7.992105 activin A receptor, 1422098_at 11479 Acvr1b 3 - up 344 SQ only type 1B 0.175621 1.640143 7.8E-05 7.811578

1428751_at 69310 Pacrg 3 - up 344 SQ only Park2 co-regulated 0.35141 1.749711 0.00104 7.795039

autism susceptibility 1438680_at 319974 Auts2 3 - up 344 SQ only candidate 2 0.219746 0.819009 2.1E-06 7.713315 golgi phosphoprotein 1428875_at 73124 Golph4 3 - up 344 SQ only 4 0.029966 1.694414 1.7E-05 7.642692 retinol binding 1426225_at 19662 Rbp4 3 - up 344 SQ only protein 4, plasma 0.984687 1.792982 4.3E-05 7.490261 cubilin (intrinsic factor-cobalamin 1452270_s_at 65969 Cubn 3 - up 344 SQ only receptor) 0.371534 0.891411 1.6E-06 7.482898 PR domain 1440745_at 70673 Prdm16 3 - up 344 SQ only containing 16 0.255495 1.752599 0.00017 7.430591 bruno-like 4, RNA binding protein 1426929_at 108013 Brunol4 3 - up 344 SQ only (Drosophila) 0.053406 2.277518 5.4E-06 7.414003 1419127_at 109648 Npy 3 - up 344 SQ only neuropeptide Y 0.552003 0.941591 0.008 7.377533 1455412_at ------3 - up 344 SQ only --- 0.727404 1.050526 1.9E-06 7.366074 GRAM domain 1435229_at 235283 Gramd1b 3 - up 344 SQ only containing 1B 0.601037 1.316882 0.00191 7.117832 RIKEN cDNA 1437558_at 320860 B130021B11R 3 - up 344 SQ only B130021B11 gene 0.750507 1.583558 0.00011 6.884775 1418220_at 14238 Foxf2 3 - up 344 SQ only forkhead box F2 0.963346 1.205612 0.00011 6.715037 RasGEF domain 1454742_at 320292 Rasgef1b 3 - up 344 SQ only family, member 1B 0.076537 1.557655 3.3E-05 6.714827

phosphodiesterase 4D interacting 1417626_at 83679 Pde4dip 3 - up 344 SQ only protein (myomegalin) 0.072386 1.630157 4.6E-06 6.587467 selenium binding 1450699_at 20341 Selenbp1 3 - up 344 SQ only protein 1 0.260815 0.805163 6.2E-06 6.529682 1434958_at 50720 Sacs 3 - up 344 SQ only sacsin 0.042399 2.205986 7.8E-05 6.464385 myotubularin related 1447831_s_at 54384 Mtmr7 3 - up 344 SQ only protein 7 0.515292 1.130249 3.6E-05 6.447077

Hypothetical protein 1440654_at 574403 MGC99845 3 - up 344 SQ only LOC574403 0.09913 1.668158 4.4E-05 6.435378

Autism susceptibility 1443770_x_at 319974 Auts2 3 - up 344 SQ only candidate 2 0.452046 0.810908 0.0009 6.405737 transmembrane 1424652_at 232146 Tmem166 3 - up 344 SQ only protein 166 0.906377 0.985175 0.00012 6.403411 1448735_at 12870 Cp 3 - up 344 SQ only ceruloplasmin 0.186378 0.670004 0.00048 6.362513 RIKEN cDNA 1460468_s_at 72778 2810451A06Ri 3 - up 344 SQ only 2810451A06 gene 0.238129 0.700867 1.4E-05 6.35402 R3H domain 1 (binds single- stranded nucleic 1457336_at 226412 R3hdm1 3 - up 344 SQ only acids) 0.355918 0.867679 0.00994 6.05423 hydroxy-delta-5- steroid dehydrogenase, 3 beta- and steroid 1425127_at 15493 Hsd3b2 3 - up 344 SQ only delta-isomerase 2 0.389128 1.377493 0.00113 5.959737 ankyrin repeat and sterile alpha motif domain containing 1B /// similar to AIDA- 1460449_at 544718 // Anks1b /// LOC3 - up 344 SQ only 1b 0.948606 1.119092 0.00082 5.944872 Protein tyrosine phosphatase, 1436367_at 19263 Ptprb 3 - up 344 SQ only receptor type, B 0.142107 1.6515 3.5E-06 5.888869 1447845_s_at 22361 Vnn1 3 - up 344 SQ only vanin 1 0.051578 2.478571 0.00142 5.864209 spondin 2, extracellular matrix 1417860_a_at 100689 Spon2 3 - up 344 SQ only protein 0.851457 1.049596 0.0006 5.863968 GATA binding 1450126_at 14464 Gata5 3 - up 344 SQ only protein 5 0.365154 0.73207 0.00175 5.699964 cytokine receptor- 1418476_at 12931 Crlf1 3 - up 344 SQ only like factor 1 0.526481 0.811 0.00142 5.627399

3'- phosphoadenosine 5'-phosphosulfate 1421989_s_at 23972 Papss2 3 - up 344 SQ only synthase 2 0.516065 1.111889 0.00084 5.620487

similar to Beta-1,4- galactosyltransferas e 6 (Beta-1,4- GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (UDP- galactose:beta-N- acetylglucosamine beta-1,4- galactosyltransferas e 6) (UDP-Gal:beta- GlcNAc beta-1,4- galactosyltransferas 1435758_at 675709 LOC675709 3 - up 344 SQ only e 6) 0.055288 1.60633 3.9E-06 5.566081

mutated in colorectal 1438081_at 328949 Mcc 3 - up 344 SQ only cancers 0.829171 1.342717 0.00162 5.539896 RAS, guanyl 1438030_at 240168 Rasgrp3 3 - up 344 SQ only releasing protein 3 0.114573 1.477831 0.00217 5.488888 1444111_at ------3 - up 344 SQ only --- 0.749456 1.004125 0.00205 5.456591 imprinted and 1415911_at 16210 Impact 3 - up 344 SQ only ancient 0.462086 1.112794 4.8E-05 5.385496

1456770_at 243906 Zfp14 3 - up 344 SQ only zinc finger protein 14 0.608314 1.91586 0.0073 5.222487

serine (or cysteine) peptidase inhibitor, 1416318_at 66222 Serpinb1a 3 - up 344 SQ only clade B, member 1a 0.170611 1.666796 0.00509 5.153235 transmembrane 1428077_at 72160 Tmem163 3 - up 344 SQ only protein 163 0.03406 2.164637 0.00025 5.038867 similar to Beta-1,4- galactosyltransferas e 6 (Beta-1,4- GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (UDP- galactose:beta-N- acetylglucosamine beta-1,4- galactosyltransferas e 6) (UDP-Gal:beta- GlcNAc beta-1,4- galactosyltransferas 1460329_at 675709 LOC675709 3 - up 344 SQ only e 6) 0.045904 1.749208 4.4E-06 4.948932 Zinc finger protein 1456789_at 242466 Zfp462 3 - up 344 SQ only 462 0.486911 2.136975 0.00049 4.925588 S100 calcium 1424542_at 20198 S100a4 3 - up 344 SQ only binding protein A4 0.153154 1.356954 0.0062 4.906666

bone morphogenetic 1422912_at 12159 Bmp4 3 - up 344 SQ only protein 4 0.337634 0.776225 0.00513 4.883886 G protein-coupled 1439489_at 107221 Gpr120 3 - up 344 SQ only receptor 120 0.273927 0.704627 0.00232 4.866235 1425789_s_at 11752 Anxa8 3 - up 344 SQ only annexin A8 0.024823 2.150343 0.00091 4.84833

solute carrier family 1428805_at 215436 Slc35e3 3 - up 344 SQ only 35, member E3 0.005562 1.317763 2E-06 4.847545 transmembrane 4 superfamily member 1424962_at 229302 Tm4sf4 3 - up 344 SQ only 4 0.316513 1.758465 0.0015 4.785653 RIKEN cDNA 1416200_at 77125 9230117N10Ri3 - up 344 SQ only 9230117N10 gene 0.21136 1.296211 0.00012 4.778013 protein tyrosine phosphatase, 1453908_at 19263 Ptprb 3 - up 344 SQ only receptor type, B 0.721228 1.316208 0.00041 4.768585

neural cell adhesion 1426865_a_at 17967 Ncam1 3 - up 344 SQ only molecule 1 0.824709 1.075421 0.00225 4.629046

serine (or cysteine) peptidase inhibitor, 1448301_s_at 66222 Serpinb1a 3 - up 344 SQ only clade B, member 1a 0.115147 1.816127 0.00255 4.621883

solute carrier family 9 (sodium/hydrogen exchanger), isoform 1439368_a_at 65962 Slc9a3r2 3 - up 344 SQ only 3 regulator 2 0.419364 0.817699 0.00025 4.591054 protein tyrosine phosphatase, 1427486_at 19263 Ptprb 3 - up 344 SQ only receptor type, B 0.281145 1.477006 5.5E-05 4.577528 1436546_at 280411 Lix1l 3 - up 344 SQ only Lix1-like 0.110525 1.83553 4.8E-06 4.521201 amyloid beta (A4) precursor protein- binding, family B, 1423893_x_at 11785 Apbb1 3 - up 344 SQ only member 1 0.220012 1.533936 0.0004 4.508551 RIKEN cDNA 1454701_at 269033 4930503L19Ri 3 - up 344 SQ only 4930503L19 gene 0.088349 1.771543 0.004 4.484298

serine (or cysteine) peptidase inhibitor, 1419082_at 18788 Serpinb2 3 - up 344 SQ only clade B, member 2 0.511909 1.627049 0.00609 4.472605

growth differentiation 1418949_at 23886 Gdf15 3 - up 344 SQ only factor 15 0.405995 0.84729 0.0004 4.472227 1455913_x_at 22139 Ttr 3 - up 344 SQ only transthyretin 0.862434 4.641874 0.00319 4.438064 1455037_at 18845 Plxna2 3 - up 344 SQ only plexin A2 0.757774 0.862353 0.00092 4.422304 zinc finger protein 1417848_at 170753 Zfp704 3 - up 344 SQ only 704 0.20888 1.586962 6.7E-05 4.403703 1418486_at 22361 Vnn1 3 - up 344 SQ only vanin 1 0.081133 1.94235 0.00182 4.393527

expressed sequence 1437661_at 239691 AU021092 3 - up 344 SQ only AU021092 0.199474 1.439996 0.00247 4.33305

UDP- Gal:betaGlcNAc beta 1,4- galactosyltransferas e, polypeptide 6 /// similar to Beta-1,4- galactosyltransferas e 6 (Beta-1,4- GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (UDP- galactose:beta-N- acetylglucosamine beta-1,4- galactosyltransferas e 6) (UDP-Gal:beta- GlcNAc beta-1,4- galactosyltransferas 1423228_at 56386 /// B4galt6 /// LOC3 - up 344 SQ only e 6) 0.323143 1.425969 0.00078 4.304628 RIKEN cDNA 1421675_at 76658 1700123K08Ri 3 - up 344 SQ only 1700123K08 gene 0.464125 1.605211 0.00203 4.303343

suppressor of 1438470_at 216233 Socs2 3 - up 344 SQ only cytokine signaling 2 0.002296 1.977123 2.4E-05 4.288918 1457317_at ------3 - up 344 SQ only --- 0.434219 1.248806 0.00313 4.256521 Kruppel-like factor 1439847_s_at 16597 Klf12 3 - up 344 SQ only 12 0.043354 1.570003 0.00055 4.253373 selenium binding 1417580_s_at 20341 Selenbp1 3 - up 344 SQ only protein 1 0.054378 0.723899 2E-06 4.249989 1435409_at ------3 - up 344 SQ only Transcribed locus 0.960265 0.953561 0.00356 4.248719

solute carrier family 9 (sodium/hydrogen exchanger), isoform 1439369_x_at 65962 Slc9a3r2 3 - up 344 SQ only 3 regulator 2 0.514462 0.889008 8E-05 4.24492 Dehydrogenase/redu ctase (SDR family) 1447678_at 66065 Dhrs10 3 - up 344 SQ only member 10 0.689479 1.11152 0.00205 4.170777 1420287_at ------3 - up 344 SQ only Transcribed locus 0.626808 1.947757 3.4E-05 4.146702 dehydrogenase/redu ctase (SDR family) 1429802_at 66065 Dhrs10 3 - up 344 SQ only member 10 0.77965 0.97737 0.00172 4.143528 1433812_at 280411 Lix1l 3 - up 344 SQ only Lix1-like 0.154199 1.767652 4.2E-06 4.132556

0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230062K19 product:unclassifiabl e, full insert 1460044_at ------3 - up 344 SQ only sequence 0.063072 1.569024 0.00012 4.10538

3'- phosphoadenosine 5'-phosphosulfate 1434510_at 23972 Papss2 3 - up 344 SQ only synthase 2 0.163133 0.825522 0.00029 4.074757 1458453_at 380928 Lmo7 3 - up 344 SQ only LIM domain only 7 0.772964 0.844064 0.00303 4.01344 cubilin (intrinsic factor-cobalamin 1426990_at 65969 Cubn 3 - up 344 SQ only receptor) 0.43302 1.198936 0.00025 3.999173

cell death-inducing DNA fragmentation factor, alpha subunit- 1418976_s_at 12684 Cideb 3 - up 344 SQ only like effector B 0.502829 0.91226 1.3E-06 3.993472

1449965_at 17231 Mcpt8 3 - up 344 SQ only mast cell protease 8 0.148409 0.627564 0.00222 3.966711 bruno-like 4, RNA binding protein 1426930_at 108013 Brunol4 3 - up 344 SQ only (Drosophila) 0.292631 1.465031 0.00131 3.95957 hematopoietically expressed 1423319_at 15242 Hhex 3 - up 344 SQ only homeobox 0.038964 1.670958 0.00054 3.940403

2 days neonate sympathetic ganglion cDNA, RIKEN full-length enriched library, clone:7120457A19 product:unclassifiabl e, full insert 1440371_at ------3 - up 344 SQ only sequence 0.627601 1.538923 0.00528 3.93997 1447920_at 54138 Atxn10 3 - up 344 SQ only Ataxin 10 0.689683 1.059102 0.00202 3.929078 1437112_at 18805 Pld1 3 - up 344 SQ only phospholipase D1 0.212369 1.457655 0.00192 3.927471 dynein, axonemal, light intermediate 1436126_at 75563 Dnali1 3 - up 344 SQ only polypeptide 1 0.94737 1.193165 0.00483 3.904903 protein tyrosine phosphatase, 1422541_at 19274 Ptprm 3 - up 344 SQ only receptor type, M 0.173887 1.318158 0.00047 3.861361 pregnancy-specific 1418416_x_at 56868 Psg23 3 - up 344 SQ only glycoprotein 23 0.907757 1.0304 7.8E-05 3.85221

Zic finger protein of 1421301_at 22772 Zic2 3 - up 344 SQ only the cerebellum 2 0.201334 0.614192 0.00136 3.842575

phospholipase A2, 1416626_at 18778 Pla2g1b 3 - up 344 SQ only group IB, pancreas 0.882482 0.997176 0.00287 3.838713 aldo-keto reductase family 1, member 1418672_at 27384 Akr1c13 3 - up 344 SQ only C13 0.091362 2.204798 9E-05 3.835925

Mus musculus, clone IMAGE:3983419, 1427195_at ------3 - up 344 SQ only mRNA 0.015674 0.6517 0.00024 3.833397

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 1449202_at 26456 Sema4g 3 - up 344 SQ only (semaphorin) 4G 0.664135 1.177034 0.00069 3.817088 1454608_x_at 22139 Ttr 3 - up 344 SQ only transthyretin 0.542048 3.874111 0.0012 3.801239

DnaJ (Hsp40) homolog, subfamily 1434196_at 58233 Dnaja4 3 - up 344 SQ only A, member 4 0.03905 1.514401 0.00011 3.782853

solute carrier family 15 (H+/peptide transporter), member 1417600_at 57738 Slc15a2 3 - up 344 SQ only 2 0.044469 0.717264 0.00016 3.73056

ATP-binding cassette, sub-family C (CFTR/MRP), 1435685_x_at 27416 Abcc5 3 - up 344 SQ only member 5 0.054032 1.669575 0.00453 3.730159

solute carrier family 9 (sodium/hydrogen exchanger), isoform 1428955_x_at 65962 Slc9a3r2 3 - up 344 SQ only 3 regulator 2 0.710868 0.968986 2.9E-05 3.663727 paired related 1432331_a_at 20204 Prrx2 3 - up 344 SQ only homeobox 2 0.102428 1.55568 0.00247 3.66064 macrophage stimulating 1 receptor (c-met- related tyrosine 1420461_at 19882 Mst1r 3 - up 344 SQ only kinase) 0.48833 1.41239 0.00027 3.654326 cDNA sequence 1440218_at 268663 BC040758 3 - up 344 SQ only BC040758 0.541974 0.946307 0.00052 3.651707 ankyrin repeat 1421651_at 52024 Ankrd22 3 - up 344 SQ only domain 22 0.488241 1.439122 0.00887 3.640719 fatty acid desaturase 1423680_at 76267 Fads1 3 - up 344 SQ only 1 0.427191 1.394991 0.00024 3.627689 GATA binding 1425464_at 14465 Gata6 3 - up 344 SQ only protein 6 0.21178 1.368636 0.00071 3.624521 RIKEN cDNA 1428795_at 76306 1110021L09Ri 3 - up 344 SQ only 1110021L09 gene 0.379401 1.293265 0.00031 3.615905 phospholipase C, 1452398_at 74055 Plce1 3 - up 344 SQ only epsilon 1 0.396886 1.592859 0.00022 3.615047

FAD-dependent oxidoreductase 1434414_at 239554 Foxred2 3 - up 344 SQ only domain containing 2 0.769247 1.440923 2.4E-05 3.612337 G protein-coupled 1423824_at 68151 Gpr177 3 - up 344 SQ only receptor 177 0.431355 1.502661 0.00169 3.605551 1420018_s_at 216350 Tspan8 3 - up 344 SQ only tetraspanin 8 0.336331 1.399752 0.00015 3.59827 zinc finger protein interacting with K 1433946_at 22775 Zik1 3 - up 344 SQ only protein 1 0.128876 1.749929 9.7E-05 3.592026 hepatic nuclear 1427000_at 15378 Hnf4a 3 - up 344 SQ only factor 4, alpha 0.477946 0.981931 1.1E-05 3.580863 bruno-like 4, RNA binding protein 1452240_at 108013 Brunol4 3 - up 344 SQ only (Drosophila) 0.106857 1.434659 7.6E-06 3.575689 serum deprivation 1443832_s_at 20324 Sdpr 3 - up 344 SQ only response 0.504173 1.425967 0.00561 3.558978

cytochrome P450, family 39, subfamily 1418780_at 56050 Cyp39a1 3 - up 344 SQ only a, polypeptide 1 0.044392 1.773961 4.4E-05 3.552377 RIKEN cDNA 1436025_at 108686 A430106J12Ri 3 - up 344 SQ only A430106J12 gene 0.041998 1.806717 1.2E-05 3.523551 RIKEN cDNA 1428866_at 72711 2810037O22R 3 - up 344 SQ only 2810037O22 gene 0.188561 1.787983 0.00223 3.518163 Solute carrier family 26 (sulfate transporter), member 1443882_at 13521 Slc26a2 3 - up 344 SQ only 2 0.032181 0.635346 0.00056 3.514091 tripartite motif 1417027_at 80890 Trim2 3 - up 344 SQ only protein 2 0.038164 1.797467 0.00299 3.497575 tudor and KH domain containing 1453366_at 72634 Tdrkh 3 - up 344 SQ only protein 0.983754 0.987144 0.00775 3.496241 1443847_x_at ------3 - up 344 SQ only Transcribed locus 0.742354 1.152684 0.00339 3.491759 mitogen-activated 1435367_at 225724 Mapk4 3 - up 344 SQ only protein kinase 4 0.52806 1.085713 0.00965 3.490178 RIKEN cDNA 1433266_at 70241 2810416A17Ri 3 - up 344 SQ only 2810416A17 gene 0.862115 1.163808 0.00097 3.471506 fructose 1449088_at 14120 Fbp2 3 - up 344 SQ only bisphosphatase 2 0.391012 0.886143 1.8E-05 3.46984 1438452_at 74103 Nebl 3 - up 344 SQ only nebulette 0.513538 1.272682 0.00209 3.460295 1429001_at 69656 Pir 3 - up 344 SQ only pirin 0.1034 1.509291 0.00138 3.459362 RIKEN cDNA 1453846_at 69959 2810013C04Ri3 - up 344 SQ only 2810013C04 gene 0.314727 1.443422 0.00619 3.43652 UbiE-YGHL1 fusion 1456510_x_at 393082 Ubie 3 - up 344 SQ only protein 0.933902 0.976102 0.00082 3.430726 RIKEN cDNA 1444623_at 320301 E530011L22Ri 3 - up 344 SQ only E530011L22 gene 0.58105 1.049724 0.00226 3.417378 serum deprivation 1416779_at 20324 Sdpr 3 - up 344 SQ only response 0.680827 1.288297 0.00295 3.403235 1449896_at ------3 - up 344 SQ only --- 0.802491 1.015596 0.00101 3.395024 monocyte to macrophage differentiation- 1423489_at 67468 Mmd 3 - up 344 SQ only associated 0.010103 1.641192 0.00208 3.385883 1424568_at 70747 Tspan2 3 - up 344 SQ only tetraspanin 2 0.13428 1.368203 3.5E-06 3.385008 A kinase (PRKA) 1444357_at 238161 Akap6 3 - up 344 SQ only anchor protein 6 0.122973 1.671786 0.00075 3.384307 1455056_at 380928 Lmo7 3 - up 344 SQ only LIM domain only 7 0.337349 0.690299 0.00518 3.359964 G protein-coupled 1437434_a_at 68151 Gpr177 3 - up 344 SQ only receptor 177 0.73505 1.330811 0.00425 3.352401 1417732_at 11752 Anxa8 3 - up 344 SQ only annexin A8 0.029842 1.70853 5.8E-05 3.345208 cDNA sequence 1435397_at 270135 BC038156 3 - up 344 SQ only BC038156 0.039206 1.534944 1.5E-05 3.32797 carboxypeptidase B2 1432834_at 56373 Cpb2 3 - up 344 SQ only (plasma) 0.112758 1.726249 0.00094 3.309801 methyltransferase 1454858_x_at 70152 Mettl7a 3 - up 344 SQ only like 7A 0.674569 1.096389 6.1E-05 3.304056

G kinase anchoring 1417594_at 56278 Gkap1 3 - up 344 SQ only protein 1 0.226325 1.394403 0.008 3.291718 monocyte to macrophage differentiation- 1423488_at 67468 Mmd 3 - up 344 SQ only associated 0.003387 1.776308 0.00203 3.276848 paroxysmal nonkinesiogenic 1418746_at 56695 Pnkd 3 - up 344 SQ only dyskinesia 0.588073 1.168193 0.00331 3.253897

zinc finger protein, 1451046_at 22761 Zfpm1 3 - up 344 SQ only multitype 1 0.032043 1.452813 0.00193 3.251152 1419833_s_at 106952 Centd3 3 - up 344 SQ only centaurin, delta 3 0.375554 1.334793 0.00537 3.248405 RIKEN cDNA 1440409_at 70075 2210401J11Rik3 - up 344 SQ only 2210401J11 gene 0.252357 0.750388 0.00048 3.240026

small nuclear ribonucleoprotein N /// SNRPN upstream 1421063_s_at 20646 /// Snrpn /// Snurf 3 - up 344 SQ only reading frame 0.390108 1.217317 0.00213 3.233956 RIKEN cDNA 1442257_at 320860 B130021B11R 3 - up 344 SQ only B130021B11 gene 0.555583 1.142815 1.4E-05 3.221536

zinc finger, DHHC 1452655_at 70546 Zdhhc2 3 - up 344 SQ only domain containing 2 0.072322 1.797729 0.00033 3.221033 1419006_s_at 93834 Peli2 3 - up 344 SQ only pellino 2 0.400294 0.748582 0.00217 3.186881

myeloid ecotropic viral integration site- 1440091_at 17536 Mrg1 3 - up 344 SQ only related gene 1 0.404079 2.095469 0.0005 3.181737

ATP-binding cassette, sub-family C (CFTR/MRP), 1427565_a_at 27416 Abcc5 3 - up 344 SQ only member 5 0.413282 1.235501 0.0012 3.177848

ATP-binding cassette, sub-family C (CFTR/MRP), 1435684_at 27416 Abcc5 3 - up 344 SQ only member 5 0.438208 1.092796 0.00111 3.166827 transient receptor potential cation channel, subfamily 1421096_at 22063 Trpc1 3 - up 344 SQ only C, member 1 0.486918 1.116642 0.00011 3.133543 transmembrane 1433615_at 320709 Tmem117 3 - up 344 SQ only protein 117 0.450627 1.230895 0.00042 3.115554 aldo-keto reductase family 1, member 1450455_s_at 622402 Akr1c12 3 - up 344 SQ only C12 0.196134 2.029092 0.00052 3.103018 methyltransferase like 7A /// UbiE- YGHL1 fusion 1434150_a_at 393082 // Mettl7a /// Ubie3 - up 344 SQ only protein 0.48587 0.873136 0.00106 3.083562

suppressor of 1449109_at 216233 Socs2 3 - up 344 SQ only cytokine signaling 2 0.186552 1.417747 0.00585 3.080964 RIKEN cDNA 1440974_at 320854 9030203C11Ri3 - up 344 SQ only 9030203C11 gene 0.350101 1.249106 0.0027 3.07605

solute carrier family 9 (sodium/hydrogen exchanger), isoform 1428954_at 65962 Slc9a3r2 3 - up 344 SQ only 3 regulator 2 0.731218 0.989255 0.00014 3.072228 carbohydrate (chondroitin) 1434316_at 269941 Chsy1 3 - up 344 SQ only synthase 1 0.070807 1.204752 3E-05 3.069428 1437113_s_at 18805 Pld1 3 - up 344 SQ only phospholipase D1 0.137635 1.29327 0.00046 3.045533 spire homolog 1 1455409_at 68166 Spire1 3 - up 344 SQ only (Drosophila) 0.00634 1.434705 1.3E-05 3.042551 1420017_at 216350 Tspan8 3 - up 344 SQ only tetraspanin 8 0.43561 1.233782 0.00032 3.013658

tumor necrosis factor receptor superfamily, 1448147_at 29820 Tnfrsf19 3 - up 344 SQ only member 19 0.521699 0.835975 0.00755 2.999493 RIKEN cDNA 1452707_at 70788 4631423F02Ri 3 - up 344 SQ only 4631423F02 gene 0.7547 0.977789 0.0003 2.97957 UDP- Gal:betaGlcNAc beta 1,4- galactosyltransferas e, polypeptide 6 /// similar to Beta-1,4- galactosyltransferas e 6 (Beta-1,4- GalTase 6) (Beta4Gal-T6) (b4Gal-T6) (UDP- galactose:beta-N- acetylglucosamine beta-1,4- galactosyltransferas e 6) (UDP-Gal:beta- GlcNAc beta-1,4- galactosyltransferas 1450913_at 56386 /// B4galt6 /// LOC3 - up 344 SQ only e 6) 0.520142 1.474923 0.00022 2.973806 retinol binding 1422846_at 19660 Rbp2 3 - up 344 SQ only protein 2, cellular 0.800054 0.939672 0.00443 2.969576 zinc finger protein 1423835_at 218820 Zfp503 3 - up 344 SQ only 503 0.776306 0.956642 0.00101 2.956426 RIKEN cDNA 1455538_at 109169 6330403M23R 3 - up 344 SQ only 6330403M23 gene 0.143757 1.180757 0.00025 2.937929 RIKEN cDNA 1433836_a_at 213393 8430408G22R 3 - up 344 SQ only 8430408G22 gene 0.839342 0.971262 0.00373 2.894841

glutamate receptor, 1421569_at 14803 Grid1 3 - up 344 SQ only ionotropic, delta 1 0.362979 1.403306 0.00948 2.893554 1450268_at 60344 Fign 3 - up 344 SQ only fidgetin 0.942188 1.016886 0.00022 2.886924 1449982_at 16156 Il11 3 - up 344 SQ only interleukin 11 0.672977 0.932769 0.00214 2.866334 microtubule- associated protein, RP/EB family, 1451989_a_at 212307 Mapre2 3 - up 344 SQ only member 2 0.89368 1.17636 0.00051 2.825664 hepatic nuclear 1421983_s_at 15378 Hnf4a 3 - up 344 SQ only factor 4, alpha 0.764023 1.031281 0.00081 2.809692 glial cells missing homolog 2 1420456_at 107889 Gcm2 3 - up 344 SQ only (Drosophila) 0.737272 0.904543 0.00471 2.798447 1438428_at 57339 Jph1 3 - up 344 SQ only Junctophilin 1 0.95551 1.027851 0.00907 2.797559 ankyrin repeat 1433742_at 107351 Ankrd15 3 - up 344 SQ only domain 15 0.067038 1.633272 0.00026 2.79444 potassium voltage- gated channel, shaker-related subfamily, beta 1448468_a_at 16497 Kcnab1 3 - up 344 SQ only member 1 0.202617 1.376665 0.00929 2.788302

suppressor of 1418507_s_at 216233 Socs2 3 - up 344 SQ only cytokine signaling 2 0.193889 1.20289 0.00094 2.780881 creatine kinase, 1455106_a_at 12709 Ckb 3 - up 344 SQ only brain 0.111558 0.837678 0.00734 2.776971 stearoyl-Coenzyme 1415965_at 20249 Scd1 3 - up 344 SQ only A desaturase 1 0.468947 1.099715 1.4E-05 2.774456

1456483_at 22750 Zfp9 3 - up 344 SQ only zinc finger protein 9 0.086596 1.799968 5.4E-05 2.773402 jumonji, AT rich interactive domain 1427142_s_at 75605 Jarid1b 3 - up 344 SQ only 1B (Rbp2 like) 0.183206 1.219608 3E-05 2.772573 1437181_at 93834 Peli2 3 - up 344 SQ only pellino 2 0.367247 0.856258 6.4E-05 2.755242 RIKEN cDNA 1428796_at 74503 5530401J07Rik3 - up 344 SQ only 5530401J07 gene 0.292534 1.733107 1.1E-05 2.747069

1455687_at 56542 Ick 3 - up 344 SQ only intestinal cell kinase 0.002075 1.336736 6E-06 2.743748 BAI1-associated 1451539_at 66898 Baiap2l1 3 - up 344 SQ only protein 2-like 1 0.210306 0.839688 0.0002 2.743699 serum deprivation 1416778_at 20324 Sdpr 3 - up 344 SQ only response 0.954574 1.065075 0.00032 2.737792 mitogen activated protein kinase 1426850_a_at 26399 Map2k6 3 - up 344 SQ only kinase 6 0.05118 1.516561 0.00542 2.727311

RIKEN cDNA 1428909_at 319269 A130040M12R3 - up 344 SQ only A130040M12 gene 0.187367 0.822693 0.00067 2.711714 dihydropyrimidinase- 1454613_at 22240 Dpysl3 3 - up 344 SQ only like 3 0.223226 1.44091 0.00094 2.68657 nicotinate phosphoribosyltransf erase domain 1454748_at 223646 Naprt1 3 - up 344 SQ only containing 1 0.529697 0.883171 0.00063 2.681144

Peroxisome proliferative activated receptor, gamma, coactivator 1434099_at 19017 Ppargc1a 3 - up 344 SQ only 1 alpha 0.350651 0.824698 0.00018 2.67891

calcium channel, voltage-dependent, 1452476_at 12296 Cacnb2 3 - up 344 SQ only beta 2 subunit 0.19439 1.401369 0.00623 2.678156

low density lipoprotein receptor class A domain 1438666_at 241576 Ldlrad3 3 - up 344 SQ only containing 3 0.805694 1.092183 0.00157 2.638349 1443660_at 18183 Nrg3 3 - up 344 SQ only Neuregulin 3 0.192372 1.512216 0.00459 2.634817 zinc finger protein 1451518_at 236193 Zfp709 3 - up 344 SQ only 709 0.797759 1.625806 0.00021 2.633071 1441299_at ------3 - up 344 SQ only Transcribed locus 0.730831 1.125 0.0041 2.629167 glycosyltransferase 25 domain 1433495_at 234407 Glt25d1 3 - up 344 SQ only containing 1 0.869533 0.976881 6.8E-05 2.628096 1447892_at ------3 - up 344 SQ only --- 0.088528 1.456985 0.00787 2.622002

expressed sequence 1433897_at 103266 AI597468 3 - up 344 SQ only AI597468 0.54694 1.15048 2.9E-05 2.607317 insulin receptor 1443969_at 384783 Irs2 3 - up 344 SQ only substrate 2 0.694528 0.956379 0.00319 2.602529 Expressed sequence 1440084_at 103819 AI663975 3 - up 344 SQ only AI663975 0.014732 1.500509 0.00105 2.593196 procollagen, type 1453191_at 373864 Col27a1 3 - up 344 SQ only XXVII, alpha 1 0.311814 1.540999 0.00842 2.591616 1424567_at 70747 Tspan2 3 - up 344 SQ only tetraspanin 2 0.303554 1.330042 0.00013 2.590353 1455948_x_at 17182 Matn3 3 - up 344 SQ only matrilin 3 0.624126 0.964118 0.00241 2.573411 tripartite motif 1426784_at 217333 Trim47 3 - up 344 SQ only protein 47 0.845689 1.014485 0.00592 2.57071

expressed sequence 1460342_s_at 26936 AA536749 3 - up 344 SQ only AA536749 0.16723 1.18515 7.1E-06 2.56717 RIKEN cDNA 1429468_at 68594 1110018F16Ri 3 - up 344 SQ only 1110018F16 gene 0.068578 1.497686 0.00079 2.566249 1420019_at 216350 Tspan8 3 - up 344 SQ only Tetraspanin 8 0.539448 0.895128 0.00257 2.563331 early growth 1436329_at 13655 Egr3 3 - up 344 SQ only response 3 0.87487 1.042044 0.00035 2.56254 RIKEN cDNA 1438321_x_at 75007 4930504E06Ri 3 - up 344 SQ only 4930504E06 gene 0.756781 0.967355 0.00025 2.556815

DnaJ (Hsp40) homolog, subfamily 1431734_a_at 67035 Dnajb4 3 - up 344 SQ only B, member 4 0.590018 1.104499 0.00965 2.55514 1438610_a_at 12972 Cryz 3 - up 344 SQ only Crystallin, zeta 0.038545 1.574 5.6E-05 2.553674 1436869_at 20423 Shh 3 - up 344 SQ only sonic hedgehog 0.839897 0.968704 0.00084 2.553003 squamous cell carcinoma antigen recognized by T 1455795_at 212898 Sart2 3 - up 344 SQ only cells 2 0.349076 1.63191 0.00012 2.550485 RIKEN cDNA 1439014_at 239796 1600021P15Ri 3 - up 344 SQ only 1600021P15 gene 0.911205 0.989641 0.00044 2.54666 1455978_a_at 17181 Matn2 3 - up 344 SQ only matrilin 2 0.547416 1.351302 0.00125 2.525099 tripartite motif 1459860_x_at 80890 Trim2 3 - up 344 SQ only protein 2 0.292319 1.338565 0.00775 2.524287

RUN and SH3 1426792_s_at 100213 Rusc2 3 - up 344 SQ only domain containing 2 0.675255 1.079901 0.00064 2.523368 1451339_at 211389 Suox 3 - up 344 SQ only sulfite oxidase 0.823943 1.034745 0.0002 2.515825 1443401_at 56079 Astn2 3 - up 344 SQ only Astrotactin 2 0.113221 1.526359 0.00074 2.50848 1445223_at ------3 - up 344 SQ only --- 0.538033 1.16491 0.00071 2.491469 spermatogenesis 1442456_at 57815 Spata5 3 - up 344 SQ only associated 5 0.978536 1.042888 0.00754 2.488716 zinc finger 1418926_at 21417 Zfhx1a 3 - up 344 SQ only homeobox 1a 0.102695 1.260082 1.7E-05 2.482845 1419442_at 17181 Matn2 3 - up 344 SQ only matrilin 2 0.080492 1.674863 9.8E-07 2.479396

2 days pregnant adult female oviduct cDNA, RIKEN full- length enriched library, clone:E230030F22 product:unclassifiabl e, full insert 1455724_at ------3 - up 344 SQ only sequence 0.848838 1.218425 0.00542 2.476769 1441678_at ------3 - up 344 SQ only --- 0.123723 1.55371 0.00078 2.474053 G protein-coupled 1423825_at 68151 Gpr177 3 - up 344 SQ only receptor 177 0.508258 1.399504 0.00413 2.472928 cDNA sequence 1437872_at 242864 AB112350 3 - up 344 SQ only AB112350 0.671889 1.083381 0.00346 2.44211 glutamate-cysteine ligase, catalytic 1424296_at 14629 Gclc 3 - up 344 SQ only subunit 0.18196 1.375984 0.00131 2.434028

solute carrier family 7 (cationic amino acid transporter, y+ 1417392_a_at 20540 Slc7a7 3 - up 344 SQ only system), member 7 0.131911 1.275544 0.00119 2.430634 RIKEN cDNA 1437403_at 320825 E130306M17R3 - up 344 SQ only E130306M17 gene 0.495429 1.080608 0.00091 2.424542 RIKEN cDNA 1426655_a_at 75007 4930504E06Ri 3 - up 344 SQ only 4930504E06 gene 0.940223 0.982828 0.00147 2.420866 fibroblast growth 1423136_at 14164 Fgf1 3 - up 344 SQ only factor 1 0.48773 0.911248 0.00161 2.420044 RIKEN cDNA 1452703_at 74340 4631427C17Ri3 - up 344 SQ only 4631427C17 gene 0.975813 1.002967 0.00097 2.401473 prokineticin receptor 1456543_at 58182 Prokr1 3 - up 344 SQ only 1 0.825294 1.078797 0.00159 2.40039

Mus musculus, clone IMAGE:4527696, 1452287_at ------3 - up 344 SQ only mRNA 0.347004 1.158456 0.00724 2.398427

1451335_at 231507 Plac8 3 - up 344 SQ only placenta-specific 8 0.291993 0.850594 3.5E-06 2.393168

expressed sequence 1456763_at 26936 AA536749 3 - up 344 SQ only AA536749 0.226977 1.117008 1.1E-05 2.388923 1456292_a_at 22352 Vim 3 - up 344 SQ only vimentin 0.131642 1.389013 0.00027 2.388674

growth arrest and DNA-damage- 1453851_a_at 23882 Gadd45g 3 - up 344 SQ only inducible 45 gamma 0.97189 0.990788 0.00775 2.387392

1449527_at 93878 Pcdhb7 3 - up 344 SQ only protocadherin beta 7 0.661248 1.046936 0.00091 2.382298

pleckstrin homology- like domain, family 1424468_s_at 102693 Phldb1 3 - up 344 SQ only B, member 1 0.939623 1.025558 0.00018 2.373828

DnaJ (Hsp40) homolog, subfamily 1451177_at 67035 Dnajb4 3 - up 344 SQ only B, member 4 0.284938 1.200074 0.00039 2.370992

microtubule associated monoxygenase, calponin and LIM 1456439_x_at 171580 Mical1 3 - up 344 SQ only domain containing 1 0.631916 1.05944 0.00122 2.366902 chemokine (C motif) 1419412_at 16963 Xcl1 3 - up 344 SQ only ligand 1 0.61068 1.260541 0.00099 2.365331 RIKEN cDNA 1435829_at 215693 B930008K04R 3 - up 344 SQ only B930008K04 gene 0.291205 1.554819 3.8E-05 2.36341 calcium channel, voltage-dependent, 1456401_at 12296 Cacnb2 3 - up 344 SQ only beta 2 subunit 0.430528 1.19707 0.00084 2.356654 RIKEN cDNA 1429106_at 70857 4921509J17Rik3 - up 344 SQ only 4921509J17 gene 0.148512 1.606724 3.7E-05 2.352084 transmembrane 1454709_at 100201 Tmem64 3 - up 344 SQ only protein 64 0.245792 0.829239 0.00061 2.339529 1417389_at 14733 Gpc1 3 - up 344 SQ only glypican 1 0.304075 1.302941 0.00526 2.333224

scavenger receptor 1454704_at 12492 Scarb2 3 - up 344 SQ only class B, member 2 0.013309 1.309785 4.4E-05 2.333049 1449388_at 21828 Thbs4 3 - up 344 SQ only thrombospondin 4 0.89761 1.02752 0.008 2.326543 leucine rich repeat containing 8 family, 1455398_at 100604 Lrrc8c 3 - up 344 SQ only member C 0.384774 1.19134 0.00299 2.32602 cytochrome P450, family 7, subfamily b, 1421074_at 13123 Cyp7b1 3 - up 344 SQ only polypeptide 1 0.543525 1.191709 0.00628 2.321342 cAMP responsive element binding 1419295_at 26427 Creb3l1 3 - up 344 SQ only protein 3-like 1 0.466644 1.314503 0.00522 2.316806 zinc finger and BTB domain containing 1432459_a_at 58206 Zbtb32 3 - up 344 SQ only 32 0.109928 1.405676 6.7E-05 2.311199

glucosaminyl (N- acetyl) transferase 3, 1430963_at 72077 Gcnt3 3 - up 344 SQ only mucin type 0.200658 0.726424 0.00864 2.307298 YTH domain 1437357_at 240255 Ythdc2 3 - up 344 SQ only containing 2 0.793218 1.072974 9.9E-06 2.306843 zinc finger and BTB domain containing 1437598_at 56490 Zbtb20 3 - up 344 SQ only 20 0.452428 1.130652 0.00115 2.304247 1416795_at 68631 Cryl1 3 - up 344 SQ only crystallin, lamda 1 0.120418 1.514453 2.3E-05 2.298397 1441658_at ------3 - up 344 SQ only Transcribed locus 0.484195 0.907847 0.00041 2.283339 adrenergic receptor, 1439762_x_at 11553 Adra2c 3 - up 344 SQ only alpha 2c 0.545767 1.108888 0.00763 2.281965 1455020_at 102141 Snx25 3 - up 344 SQ only sorting nexin 25 0.352615 1.20655 0.00191 2.281566 1450641_at 22352 Vim 3 - up 344 SQ only vimentin 0.184114 1.416679 0.00446 2.280303

Thyroid hormone receptor associated 1446840_at 327987 Thrap1 3 - up 344 SQ only protein 1 0.078146 1.454924 0.00309 2.25828

1428547_at 23959 Nt5e 3 - up 344 SQ only 5' nucleotidase, ecto 0.695251 0.970341 0.00063 2.257042 1458885_at ------3 - up 344 SQ only --- 0.960086 1.199172 0.00481 2.255692

acyl-CoA synthetase long-chain family 1428386_at 74205 Acsl3 3 - up 344 SQ only member 3 0.11621 1.552877 4E-05 2.252809 zinc finger and BTB domain containing 1422064_a_at 56490 Zbtb20 3 - up 344 SQ only 20 0.108364 1.226543 0.0063 2.2502

teashirt zinc finger 1427233_at 110796 Tshz1 3 - up 344 SQ only family member 1 0.131131 1.361366 0.00355 2.246385 RIKEN cDNA 1437885_at 99324 D030029J20Ri 3 - up 344 SQ only D030029J20 gene 0.156464 1.473815 0.00141 2.240382 RIKEN cDNA 1437216_at 108686 A430106J12Ri 3 - up 344 SQ only A430106J12 gene 0.131453 1.495302 0.0034 2.233975 kinesin family 1455746_at 16553 Kif13a 3 - up 344 SQ only member 13A 0.611271 0.91181 0.00081 2.231701 DNA segment, Chr 16, ERATO Doi 472, 1436125_at 67102 D16Ertd472e 3 - up 344 SQ only expressed 0.481194 1.128624 7.7E-05 2.229767 zinc finger protein 1423836_at 218820 Zfp503 3 - up 344 SQ only 503 0.696081 1.149368 0.00039 2.224679 DNA segment, Chr 16, ERATO Doi 472, 1429897_a_at 67102 D16Ertd472e 3 - up 344 SQ only expressed 0.35307 1.205917 0.00395 2.224077 kinesin family 1422945_a_at 16574 Kif5c 3 - up 344 SQ only member 5C 0.540467 1.15666 0.00303 2.217922 1439852_at ------3 - up 344 SQ only --- 0.480726 1.141287 0.00799 2.215071

membrane associated guanylate kinase, WW and PDZ 1454855_at 50791 Magi2 3 - up 344 SQ only domain containing 2 0.008448 1.400596 0.00014 2.213191 protein tyrosine 1419024_at 19243 Ptp4a1 3 - up 344 SQ only phosphatase 4a1 0.549183 1.075412 0.00121 2.207173 ankyrin repeat 1460559_at 235041 Ankrd25 3 - up 344 SQ only domain 25 0.382296 0.786277 0.00702 2.204571 tumor necrosis factor alpha induced 1418424_at 21930 Tnfaip6 3 - up 344 SQ only protein 6 0.597415 1.133185 0.0005 2.202561

Tial1 cytotoxic granule-associated RNA binding protein- 1426352_s_at 21843 Tial1 3 - up 344 SQ only like 1 0.729786 1.382381 0.00368 2.192965 1459991_at 270163 Myo9a 3 - up 344 SQ only myosin IXa 0.095354 1.184251 0.00171 2.19275 1451753_at 18845 Plxna2 3 - up 344 SQ only plexin A2 0.240871 0.750714 0.00368 2.189484 cAMP responsive element binding 1452381_at 208647 Creb3l2 3 - up 344 SQ only protein 3-like 2 0.233719 1.121414 5.5E-05 2.186288

Human immunodeficiency virus type I enhancer 1457932_at 15273 Hivep2 3 - up 344 SQ only binding protein 2 0.113783 1.407702 0.00819 2.182294

insulin-like growth factor binding protein 7 /// similar to O- acyltransferase (membrane bound) 1423585_at 29817 /// Igfbp7 /// LOC63 - up 344 SQ only domain containing 2 0.003119 0.806241 2.3E-05 2.176912

bobby sox homolog 1458602_at 70508 Bbx 3 - up 344 SQ only (Drosophila) 0.767655 1.587468 0.00972 2.172236 1443627_at ------3 - up 344 SQ only --- 0.329641 1.255937 0.00428 2.172154 ribonuclease, RNase 1422603_at 58809 Rnase4 3 - up 344 SQ only A family 4 0.092413 1.317809 6.9E-05 2.16941

scavenger receptor 1427020_at 219151 Scara3 3 - up 344 SQ only class A, member 3 0.449785 0.890646 0.00068 2.166432 Hydrocephalus 1441269_at 244653 Hydin 3 - up 344 SQ only inducing 0.655465 1.21497 0.00264 2.154572

Hypothetical protein 1444980_at 328974 C730009D12 3 - up 344 SQ only C730009D12 0.553044 1.090025 0.00507 2.152892

twist gene homolog 1418733_at 22160 Twist1 3 - up 344 SQ only 1 (Drosophila) 0.47355 1.200263 0.00749 2.14837 SEC23A (S. 1423347_at 20334 Sec23a 3 - up 344 SQ only cerevisiae) 0.082123 1.2866 0.00021 2.147937 UDP-N- acteylglucosamine pyrophosphorylase 1- 1436890_at 227620 Uap1l1 3 - up 344 SQ only like 1 0.112844 1.383968 0.00198 2.146866 dihydropyrimidinase- 1433770_at 12934 Dpysl2 3 - up 344 SQ only like 2 0.980355 1.003832 0.00021 2.126325 1425586_a_at 171531 Mlph 3 - up 344 SQ only melanophilin 0.474486 1.120723 0.00695 2.125105

MARVEL (membrane- associating) domain 1439381_x_at 277010 Marveld1 3 - up 344 SQ only containing 1 0.906192 0.961008 0.00454 2.121812

killer cell lectin-like receptor subfamily A, 1452645_x_at 93969 Klra22 3 - up 344 SQ only member 22 0.595046 1.784614 0.00893 2.119329 FK506 binding 1416125_at 14229 Fkbp5 3 - up 344 SQ only protein 5 0.053572 1.411574 0.00242 2.117606

expressed sequence 1435417_at 329828 AI464131 3 - up 344 SQ only AI464131 0.750336 0.96123 0.00267 2.117601

cysteine and glycine- 1420731_a_at 13008 Csrp2 3 - up 344 SQ only rich protein 2 0.137176 1.368275 0.00028 2.115525 golgi autoantigen, golgin subfamily b, 1433135_at 224139 Golgb1 3 - up 344 SQ only macrogolgin 1 0.961257 1.047385 0.00026 2.114548 Double cortin and calcium/calmodulin- dependent protein 1436659_at 13175 Dcamkl1 3 - up 344 SQ only kinase-like 1 0.088583 1.511835 0.00013 2.110446

expressed sequence 1438442_at 99634 AI450236 3 - up 344 SQ only AI450236 0.028682 1.435461 0.00074 2.109201 procollagen, type VI, 1426947_x_at 12834 Col6a2 3 - up 344 SQ only alpha 2 0.64906 0.913153 0.00198 2.108573 frizzled homolog 2 1418533_s_at 57265 Fzd2 3 - up 344 SQ only (Drosophila) 0.463994 1.346167 0.00257 2.098469

1419435_at 11761 Aox1 3 - up 344 SQ only aldehyde oxidase 1 0.983227 1.013564 0.00226 2.098338 FXYD domain- containing ion 1419378_a_at 11936 Fxyd2 3 - up 344 SQ only transport regulator 2 0.680199 1.142991 0.00562 2.096265 RIKEN cDNA 1436844_at 109169 6330403M23R 3 - up 344 SQ only 6330403M23 gene 0.768756 0.955851 0.00514 2.095379 transmembrane 1424039_at 67887 Tmem66 3 - up 344 SQ only protein 66 0.142466 1.102974 6.4E-05 2.092789 kinesin family 1431718_at 209737 Kif15 3 - up 344 SQ only member 15 0.140543 1.222082 0.00293 2.091665 immunoglobulin superfamily, member 1455048_at 78908 Igsf3 3 - up 344 SQ only 3 0.451052 1.113948 0.00095 2.0899 1418876_at 15229 Foxd1 3 - up 344 SQ only forkhead box D1 0.833622 1.035774 0.00272 2.089131

SEC24 related gene family, member D (S. 1426972_at 69608 Sec24d 3 - up 344 SQ only cerevisiae) 0.991083 1.025269 7.4E-05 2.084542 1455961_at ------3 - up 344 SQ only --- 0.819184 1.067994 0.00918 2.083787 procollagen, type VI, 1452250_a_at 12834 Col6a2 3 - up 344 SQ only alpha 2 0.603586 0.904083 0.0016 2.082335

neural cell adhesion 1450437_a_at 17967 Ncam1 3 - up 344 SQ only molecule 1 0.312716 1.173519 0.00446 2.078963 corticotropin releasing hormone 1436127_at 12919 Crhbp 3 - up 344 SQ only binding protein 0.449651 0.843736 0.00469 2.078935

acyl-Coenzyme A 1416408_at 11430 Acox1 3 - up 344 SQ only oxidase 1, palmitoyl 0.004066 1.398011 9.4E-06 2.076826

nucleolar protein 3 (apoptosis repressor 1451503_at 78688 Nol3 3 - up 344 SQ only with CARD domain) 0.731496 1.13782 0.00403 2.075008 RIKEN cDNA 1455160_at 70455 2610203C20Ri3 - up 344 SQ only 2610203C20 gene 0.693239 0.928725 0.00308 2.073972 1424649_a_at 216350 Tspan8 3 - up 344 SQ only tetraspanin 8 0.857434 1.068637 0.00034 2.073399

0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230070N19 product:myristoylate d alanine rich protein kinase C substrate, 1415973_at ------3 - up 344 SQ only full insert sequence 0.283372 1.306488 0.00289 2.069135

scratch homolog 2, zinc finger protein 1440930_a_at 545474 Scrt2 3 - up 344 SQ only (Drosophila) 0.935478 1.006032 0.00245 2.067767

neural cell adhesion 1425126_at 17967 Ncam1 3 - up 344 SQ only molecule 1 0.809199 1.039034 0.00134 2.067252 hydroxysteroid (17- beta) 1460606_at 243168 Hsd17b13 3 - up 344 SQ only dehydrogenase 13 0.495115 1.806492 0.00534 2.066167

MyoD family inhibitor 1427040_at 16543 Mdfic 3 - up 344 SQ only domain containing 0.258005 1.250228 0.00601 2.066103 RIKEN cDNA 1437291_at 108899 2700081O15R 3 - up 344 SQ only 2700081O15 gene 0.307317 1.490437 0.00865 2.065846 calcium/calmodulin- dependent protein 1422659_at 108058 Camk2d 3 - up 344 SQ only kinase II, delta 0.669642 0.91672 0.00746 2.064223

RIKEN cDNA 1458234_at 319303 A730052K04R 3 - up 344 SQ only A730052K04 gene 0.694718 0.974604 0.00061 2.063204

hypothetical protein 1442226_at 330043 6430702L12 3 - up 344 SQ only 6430702L12 0.734557 0.95199 0.00087 2.060967 1416101_a_at 50708 Hist1h1c 3 - up 344 SQ only histone 1, H1c 0.705385 1.061876 0.00794 2.057157 glutamine repeat 1421732_at 14659 Glrp1 3 - up 344 SQ only protein 1 0.076485 0.862443 1.1E-05 2.056934 tripartite motif 1448551_a_at 80890 Trim2 3 - up 344 SQ only protein 2 0.225773 1.34776 0.00776 2.056432 1419431_at 13874 Ereg 3 - up 344 SQ only epiregulin 0.800978 1.337452 0.00055 2.055725

ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A- inhibited) /// similar to ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A- 1454982_at 670796 // Arfgef2 /// LOC3 - up 344 SQ only inhibited) 0.641279 1.059347 0.00204 2.044227 1453286_at 18845 Plxna2 3 - up 344 SQ only plexin A2 0.215847 0.886052 0.00011 2.04228 RIKEN cDNA 1434084_at 77519 5730601F06Ri 3 - up 344 SQ only 5730601F06 gene 0.223962 1.307555 0.0046 2.041359 1447112_s_at 68631 Cryl1 3 - up 344 SQ only crystallin, lamda 1 0.167402 1.39012 0.00034 2.040915 RAB27b, member RAS oncogene 1439610_at 80718 Rab27b 3 - up 344 SQ only family 0.213214 0.817472 6.8E-06 2.040915

pleckstrin homology- like domain, family 1454862_at 208177 Phldb2 3 - up 344 SQ only B, member 2 0.88336 0.987567 0.00095 2.039311 snail homolog 2 1418673_at 20583 Snai2 3 - up 344 SQ only (Drosophila) 0.20161 1.273349 0.00368 2.039284 1429772_at 18845 Plxna2 3 - up 344 SQ only plexin A2 0.305865 0.885231 0.00021 2.038487

lysosomal trafficking 1434674_at 17101 Lyst 3 - up 344 SQ only regulator 0.35816 1.122799 0.00278 2.037986 KDEL (Lys-Asp-Glu- Leu) endoplasmic reticulum protein 1418538_at 105785 Kdelr3 3 - up 344 SQ only retention receptor 3 0.947994 1.011553 7.5E-05 2.036032 paired related 1439774_at 18933 Prrx1 3 - up 344 SQ only homeobox 1 0.13585 1.401419 0.0032 2.034926

hypothetical protein 1440005_at 328974 C730009D12 3 - up 344 SQ only C730009D12 0.513874 1.111627 0.00444 2.032496 RIKEN cDNA 1441279_at 78706 C430002E04R 3 - up 344 SQ only C430002E04 gene 0.4573 1.232031 0.00285 2.02838

sema domain, transmembrane domain (TM), and cytoplasmic domain, 1453055_at 214968 Sema6d 3 - up 344 SQ only (semaphorin) 6D 0.264108 1.276338 0.00473 2.028368 frequently rearranged in advanced T-cell 1455220_at 212398 Frat2 3 - up 344 SQ only lymphomas 2 0.068736 1.306152 0.00022 2.02651

ring finger and KH 1437152_at 108797 Rkhd3 3 - up 344 SQ only domain containing 3 0.17359 1.341395 0.003 2.0227 eukaryotic translation initiation factor 1A /// similar to Eukaryotic translation initiation factor 1A (eIF-1A) (eIF-4C) /// similar to GLE1 RNA export mediator-like (yeast /// similar to Eukaryotic translation initiation factor 1A (eIF-1A) (eIF-4C) /// similar to Eukaryotic translation initiation factor 1A (eIF-1A) (eIF-4C) /// similar to X-linked eukaryotic translation initiation factor 1A /// similar to X-linked eukaryotic translation initiation factor 1A /// similar to X-linked eukaryotic translation initiation factor 1A /// similar to X-linked eukaryotic translation initiation factor 1A /// similar to X-linked eukaryotic translation initiation factor 1A /// similar to X-linked eukaryotic 1427479_at 13664 /// Eif1a /// MGC1 3 - up 344 SQ only translation initiation 0.587436 2.107674 0.00546 2.021593

1448310_at 56542 Ick 3 - up 344 SQ only intestinal cell kinase 0.614416 1.053177 0.00113 2.020514 tripartite motif 1417028_a_at 80890 Trim2 3 - up 344 SQ only protein 2 0.086685 1.34117 0.00535 2.01558 Kazal-type serine peptidase inhibitor 1436528_at 107250 Kazald1 3 - up 344 SQ only domain 1 0.097868 1.321976 0.00842 2.015417 aspartate-beta- 1426015_s_at 65973 Asph 3 - up 344 SQ only hydroxylase 0.445962 1.195086 0.00507 2.014672

16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630014E16 product:unclassifiabl e, full insert 1446286_at ------3 - up 344 SQ only sequence 0.185996 0.83818 7.8E-05 2.014212 fibroblast growth 1418497_at 14168 Fgf13 3 - up 344 SQ only factor 13 0.86635 0.988609 0.00569 2.012368 RIKEN cDNA 1427878_at 66060 0610010O12R 3 - up 344 SQ only 0610010O12 gene 0.283514 0.840175 0.00292 2.011649 gamma-aminobutyric acid (GABA-A) receptor, subunit 1421190_at 14402 Gabrb3 3 - up 344 SQ only beta 3 0.916552 0.948937 0.00818 2.009937

adaptor-related protein complex AP- 1459832_s_at 11767 Ap1m1 3 - up 344 SQ only 1, mu subunit 1 0.030332 1.178016 0.00011 2.008772

membrane protein, palmitoylated 7 (MAGUK p55 1455179_at 75739 Mpp7 3 - up 344 SQ only subfamily member 7) 0.061088 1.12448 9.8E-06 2.008747 RIKEN cDNA 1425268_a_at 73182 3110045G13R 3 - up 344 SQ only 3110045G13 gene 0.74097 0.995367 0.0008 2.00753 mannoside acetylglucosaminyltr 1428644_at 107895 Mgat5 3 - up 344 SQ only ansferase 5 0.786788 0.983515 0.0024 2.00407 dihydropyrimidinase- 1415877_at 22240 Dpysl3 3 - up 344 SQ only like 3 0.413081 1.188846 0.00366 2.00237

microtubule associated monoxygenase, calponin and LIM 1416759_at 171580 Mical1 3 - up 344 SQ only domain containing 1 0.321466 1.298311 0.00612 2.002336 RIKEN cDNA 1428284_at 329540 8430427H17Ri3 - up 344 SQ only 8430427H17 gene 0.484841 0.904189 0.00106 2.002321 zinc finger, DHHC domain containing 1434236_at 75965 Zdhhc20 3 - up 344 SQ only 20 0.10226 1.282148 0.00138 2.001798 RIKEN cDNA 1440849_at 108780 6330417G04R 3 - up 344 SQ only 6330417G04 gene 0.326901 0.835669 0.00536 1.999763 RIKEN cDNA 1429773_at 72778 2810451A06Ri 3 - up 344 SQ only 2810451A06 gene 0.754642 0.956094 0.00033 1.997099 1433985_at 329165 Abi2 3 - up 344 SQ only abl-interactor 2 0.029363 1.305014 0.00018 1.996004 polycystic kidney 1417753_at 18764 Pkd2 3 - up 344 SQ only disease 2 0.312681 1.130402 0.00563 1.99313 RIKEN cDNA 1419652_s_at 67149 2610200G18R 3 - up 344 SQ only 2610200G18 gene 0.626395 1.070385 0.00136 1.992762 RIKEN cDNA 1426656_at 75007 4930504E06Ri 3 - up 344 SQ only 4930504E06 gene 0.673193 0.93592 0.00075 1.989299 histone deacetylase 1415743_at 15184 Hdac5 3 - up 344 SQ only 5 0.104591 1.261238 0.00018 1.98748 zinc finger protein 422, related 1434896_at 77652 Zfp422-rs1 3 - up 344 SQ only sequence 1 0.121004 1.315003 0.00037 1.984385 RIKEN cDNA 1424318_at 216551 1110067D22Ri3 - up 344 SQ only 1110067D22 gene 0.000602 1.309904 6.4E-05 1.981233 homocysteine- inducible, endoplasmic reticulum stress- inducible, ubiquitin- like domain member 1435626_a_at 64209 Herpud1 3 - up 344 SQ only 1 0.80412 1.02848 0.00208 1.976762 N-myc downstream 1448154_at 29811 Ndrg2 3 - up 344 SQ only regulated gene 2 0.534338 0.949838 0.00096 1.972224 procollagen, type VI, 1448590_at 12833 Col6a1 3 - up 344 SQ only alpha 1 0.54377 0.871764 0.00398 1.970302 frizzled homolog 2 1418532_at 57265 Fzd2 3 - up 344 SQ only (Drosophila) 0.549126 1.344094 0.00593 1.969949 RNA binding protein gene with multiple 1455936_a_at 19663 Rbpms 3 - up 344 SQ only splicing 0.033391 1.339412 0.00064 1.965546 testis-specific protein, Y-encoded- 1415908_at 22110 Tspyl1 3 - up 344 SQ only like 1 0.024889 1.412202 0.00014 1.962865

xenotropic and polytropic retrovirus 1426992_at 19775 Xpr1 3 - up 344 SQ only receptor 1 0.237422 1.215059 0.00943 1.958533 prostaglandin E receptor 3 (subtype 1450344_a_at 19218 Ptger3 3 - up 344 SQ only EP3) 0.679778 1.242577 0.00881 1.953303 RIKEN cDNA 1437046_x_at 75007 4930504E06Ri 3 - up 344 SQ only 4930504E06 gene 0.5187 0.956978 5.8E-07 1.950829 nudix (nucleoside diphosphate linked moiety X)-type motif 1431302_a_at 67528 Nudt7 3 - up 344 SQ only 7 0.902461 1.084274 0.00293 1.947702

1455009_at 12874 Cpd 3 - up 344 SQ only carboxypeptidase D 0.198027 1.124748 7.9E-05 1.947533

autophagy related 16 1429396_at 73683 Atg16l2 3 - up 344 SQ only like 2 (S. cerevisiae) 0.73059 1.076907 0.00871 1.945007 1455242_at 108655 Foxp1 3 - up 344 SQ only forkhead box P1 0.03821 1.413267 0.00016 1.943884

suppressor of 1435492_at 54607 Socs6 3 - up 344 SQ only cytokine signaling 6 0.790946 0.956082 0.0074 1.941099 RIKEN cDNA 1460624_at 109045 6330564D18Ri3 - up 344 SQ only 6330564D18 gene 0.286378 1.406409 0.00041 1.939165

0 day neonate cerebellum cDNA, RIKEN full-length enriched library, clone:C230070N19 product:myristoylate d alanine rich protein kinase C substrate, 1456700_x_at ------3 - up 344 SQ only full insert sequence 0.360517 1.216517 0.0016 1.938149 homocysteine- inducible, endoplasmic reticulum stress- inducible, ubiquitin- like domain member 1448185_at 64209 Herpud1 3 - up 344 SQ only 1 0.712566 1.053954 0.00253 1.93626 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily 1418467_at 66993 Smarcd3 3 - up 344 SQ only d, member 3 0.856098 1.130661 1.7E-05 1.932663

acyl-CoA synthetase long-chain family 1452771_s_at 74205 Acsl3 3 - up 344 SQ only member 3 0.310375 1.459057 0.00026 1.925759 snail homolog 2 1447643_x_at 20583 Snai2 3 - up 344 SQ only (Drosophila) 0.536774 1.078453 0.00721 1.922888

1448548_at 68842 Tulp4 3 - up 344 SQ only tubby like protein 4 0.012161 1.204334 2.5E-05 1.919187 transducin-like enhancer of split 1, homolog of 1422751_at 21885 Tle1 3 - up 344 SQ only Drosophila E(spl) 0.149299 1.121791 0.00489 1.919011 aldehyde dehydrogenase family 3, subfamily 1418752_at 11670 Aldh3a1 3 - up 344 SQ only A1 0.516208 0.918217 0.00164 1.918567 RIKEN cDNA 1447100_s_at 70617 5730508B09Ri 3 - up 344 SQ only 5730508B09 gene 0.472368 1.144016 0.00278 1.918049 aldo-keto reductase family 1, member 1422000_at 622402 Akr1c12 3 - up 344 SQ only C12 0.604128 1.400549 0.00269 1.915821 arrestin domain 1444508_s_at 215705 Arrdc1 3 - up 344 SQ only containing 1 0.441808 1.106205 0.00114 1.913395

histone 2, H3c1 /// histone 2, H2aa1 /// histone 1, H2ad /// histone 1, H2an /// histone 2, H2ab /// histone 2, H2ac /// 1418366_at 15077 /// Hist2h3c1 /// H 3 - up 344 SQ only histone 2, H2aa2 0.645805 1.037136 0.00031 1.910334 RIKEN cDNA 1429703_at 73005 2900072G11R 3 - up 344 SQ only 2900072G11 gene 0.906891 1.005377 0.0071 1.908943 1419962_at ------3 - up 344 SQ only Transcribed locus 0.872247 1.050222 0.00774 1.905237 CUG triplet repeat, RNA binding protein 1441072_at 14007 Cugbp2 3 - up 344 SQ only 2 0.485629 1.077943 0.00017 1.902453 microtubule- associated protein, RP/EB family, 1451990_at 212307 Mapre2 3 - up 344 SQ only member 2 0.470685 1.105087 3.2E-05 1.90244 protein tyrosine 1455002_at 19243 Ptp4a1 3 - up 344 SQ only phosphatase 4a1 0.899232 0.990127 0.00081 1.902067 cytoplasmic polyadenylation element binding 1437765_at 208922 Cpeb3 3 - up 344 SQ only protein 3 0.58132 1.11534 0.0037 1.898837

1456115_at 213109 Phf3 3 - up 344 SQ only PHD finger protein 3 0.285415 1.302546 0.00542 1.898374 expressed sequence 1436560_at 104598 AW124694 3 - up 344 SQ only AW124694 0.082573 1.322408 0.00818 1.896183 1423885_at 226519 Lamc1 3 - up 344 SQ only laminin, gamma 1 0.233847 1.088995 0.0001 1.894906 cDNA sequence 1451562_at 223267 BC006662 3 - up 344 SQ only BC006662 0.928047 0.9922 0.00036 1.893921

Adult male spinal cord cDNA, RIKEN full-length enriched library, clone:A330033L11 product:unclassifiabl e, full insert 1436248_at ------3 - up 344 SQ only sequence 0.442276 1.160509 0.00519 1.893563 N-acylsphingosine amidohydrolase 3- 1451355_at 230379 Asah3l 3 - up 344 SQ only like 0.99256 1.136784 0.00387 1.889791 1438118_x_at 22352 Vim 3 - up 344 SQ only vimentin 0.123164 1.250265 0.00013 1.888627 tripartite motif 1443989_at 94090 Trim9 3 - up 344 SQ only protein 9 0.120682 1.365295 0.00686 1.887533

longevity assurance homolog 6 (S. 1434418_at 241447 Lass6 3 - up 344 SQ only cerevisiae) 0.160589 1.38607 0.00283 1.883334 zinc fingers and homeoboxes protein 1448875_at 22770 Zhx1 3 - up 344 SQ only 1 0.313395 1.317531 0.00959 1.882728

PREDICTED: Mus musculus similar to Hemoglobin alpha subunit (Hemoglobin alpha chain) (Alpha- globin) (LOC383229), 1455261_at ------3 - up 344 SQ only mRNA 0.034058 1.290633 0.00055 1.879643 membrane bound C2 domain containing 1451099_at 23943 Mbc2 3 - up 344 SQ only protein 0.083189 1.351927 0.00432 1.876617

expressed sequence 1435280_at 105178 AI452195 3 - up 344 SQ only AI452195 0.664095 0.944265 0.00085 1.876062

gap junction membrane channel 1422179_at 14621 Gjb4 3 - up 344 SQ only protein beta 4 0.48378 1.111104 0.00225 1.875424 RIKEN cDNA 1437212_at 233058 B230312I18Rik3 - up 344 SQ only B230312I18 gene 0.823835 1.113828 0.00156 1.874133

eukaryotic translation initiation 1453289_at 76850 Eif2c4 3 - up 344 SQ only factor 2C, 4 0.843934 1.025779 0.00271 1.874077 UDP-glucose ceramide glucosyltransferase- 1431602_a_at 66435 Ugcgl2 3 - up 344 SQ only like 2 0.365874 1.161635 0.00417 1.871717 amyloid beta (A4) precursor protein- binding, family B, 1423892_at 11785 Apbb1 3 - up 344 SQ only member 1 0.824614 1.048965 0.00221 1.867884 1434089_at 104027 Synpo 3 - up 344 SQ only synaptopodin 0.777939 0.957566 0.00782 1.864679 RIKEN cDNA 1449553_at 67149 2610200G18R 3 - up 344 SQ only 2610200G18 gene 0.316554 1.142385 0.00287 1.861286 immunoglobulin superfamily, member 1455049_at 78908 Igsf3 3 - up 344 SQ only 3 0.40644 1.125031 0.00012 1.860565 1455440_at 26372 Clcn6 3 - up 344 SQ only chloride channel 6 0.315017 0.904364 0.00176 1.853873

Rho-associated coiled-coil containing 1423445_at 19877 Rock1 3 - up 344 SQ only protein kinase 1 0.43821 1.098906 0.00103 1.853734

purine rich element 1420628_at 19290 Pura 3 - up 344 SQ only binding protein A 0.283153 1.097715 0.0034 1.851471 DNA segment, Chr 16, ERATO Doi 472, 1424724_a_at 67102 D16Ertd472e 3 - up 344 SQ only expressed 0.387319 1.085843 0.00459 1.84959

0 day neonate thymus cDNA, RIKEN full-length enriched library, clone:A430010E21 product:unclassifiabl e, full insert 1437375_at ------3 - up 344 SQ only sequence 0.351032 1.192971 0.00594 1.8434 fibroblast growth 1438405_at 14178 Fgf7 3 - up 344 SQ only factor 7 0.055896 1.359273 0.00104 1.843059

myeloid ecotropic viral integration site- 1417129_a_at 17536 Mrg1 3 - up 344 SQ only related gene 1 0.307832 1.304565 0.00032 1.842547

1443178_at 24017 Rnf13 3 - up 344 SQ only ring finger protein 13 0.383959 0.893853 0.00146 1.840536 C1q domain 1417393_a_at 67389 C1qdc2 3 - up 344 SQ only containing 2 0.572193 1.079649 0.00822 1.839932

purine rich element 1449934_at 19290 Pura 3 - up 344 SQ only binding protein A 0.324409 1.145931 0.00904 1.837768

glutaminase 2 (liver, 1435245_at 216456 Gls2 3 - up 344 SQ only mitochondrial) 0.096574 1.271016 0.00304 1.836525

Adult male corpora quadrigemina cDNA, RIKEN full-length enriched library, clone:B230341P20 product:inferred: forkhead box P1, full 1435221_at ------3 - up 344 SQ only insert sequence 0.124639 1.21587 0.00165 1.834142 1445303_at ------3 - up 344 SQ only --- 0.978851 1.086399 0.00679 1.833164

solute carrier family 6 (neurotransmitter transporter, 1417116_at 102857 Slc6a8 3 - up 344 SQ only creatine), member 8 0.057719 1.265536 0.00015 1.831314

Tial1 cytotoxic granule-associated RNA binding protein- 1452821_at 21843 Tial1 3 - up 344 SQ only like 1 0.021791 1.334576 0.00417 1.829709 RIKEN cDNA 1455134_at 319762 A630051L19Ri 3 - up 344 SQ only A630051L19 gene 0.429454 1.189677 0.00256 1.827867 1443814_x_at 13036 Ctsh 3 - up 344 SQ only cathepsin H 0.854171 1.027155 0.00979 1.827203

ATPase family, AAA 1433870_at 217138 Atad4 3 - up 344 SQ only domain containing 4 0.660224 0.958661 0.00041 1.823299 transcription elongation factor A 1418171_at 66684 Tceal8 3 - up 344 SQ only (SII)-like 8 0.276093 1.242833 0.00947 1.822675 MAP3K12 binding 1424405_at 217588 Mbip 3 - up 344 SQ only inhibitory protein 1 0.200282 1.255601 0.00073 1.821687 caveolin, caveolae 1449145_a_at 12389 Cav1 3 - up 344 SQ only protein 1 0.628113 1.077991 0.00196 1.821682 transmembrane 1424726_at 232086 Tmem150 3 - up 344 SQ only protein 150 0.434736 1.141281 0.00634 1.818683 glutathione 1421817_at 14782 Gsr 3 - up 344 SQ only reductase 1 0.627625 0.919739 0.00284 1.818582 tetratricopeptide 1419584_at 209683 Ttc28 3 - up 344 SQ only repeat domain 28 0.366689 1.206815 0.00242 1.818269

nitric oxide synthase 1441075_at 329416 Nostrin 3 - up 344 SQ only trafficker 0.619366 0.945212 0.00249 1.8179 nudix (nucleoside diphosphate linked moiety X)-type motif 1460358_s_at 68323 Nudt22 3 - up 344 SQ only 22 0.196542 1.297424 0.00065 1.814704

solute carrier family 1417446_at 20498 Slc12a4 3 - up 344 SQ only 12, member 4 0.266518 1.279962 0.00662 1.812804 ADP-ribosylation 1442905_at 11843 Arf4 3 - up 344 SQ only factor 4 0.152537 1.184129 0.00147 1.812413 RIKEN cDNA 1424239_at 75687 2310066E14Ri 3 - up 344 SQ only 2310066E14 gene 0.019043 1.34443 2.4E-05 1.808233 pleckstrin homology domain containing, family H (with MyTH4 domain) 1460062_at 213556 Plekhh2 3 - up 344 SQ only member 2 0.380852 0.910988 0.00048 1.80815 receptor-interacting serine-threonine 1418488_s_at 72388 Ripk4 3 - up 344 SQ only kinase 4 0.254844 1.178558 0.00446 1.805985 1426246_at 19128 Pros1 3 - up 344 SQ only protein S (alpha) 0.734665 1.046725 0.00618 1.805415 1434025_at ------3 - up 344 SQ only --- 0.313455 0.887294 0.00069 1.805309 Ubiquitin-like, containing PHD and RING finger domains 1457070_at 109113 Uhrf2 3 - up 344 SQ only 2 0.043738 1.237951 0.00024 1.804245

ST3 beta- galactoside alpha- 2,3-sialyltransferase 1449198_a_at 20454 St3gal5 3 - up 344 SQ only 5 0.449976 0.872358 0.00237 1.800421

pleckstrin homology, Sec7 and coiled-coil 1418758_a_at 19159 Pscd3 3 - up 344 SQ only domains 3 0.626686 0.940454 0.00917 1.797592 trophoblast 1423312_at 21983 Tpbg 3 - up 344 SQ only glycoprotein 0.494064 1.080204 0.00062 1.79704 arsenic (+3 oxidation state) 1431980_a_at 57344 As3mt 3 - up 344 SQ only methyltransferase 0.324246 0.842578 0.00471 1.795655

GTP cyclohydrolase 1435750_at 320415 Gchfr 3 - up 344 SQ only I feedback regulator 0.360809 1.173177 0.00147 1.795483 receptor-interacting serine-threonine 1418487_at 72388 Ripk4 3 - up 344 SQ only kinase 4 0.362479 1.175611 0.00959 1.794755

expressed sequence 1433823_at 218232 AW456874 3 - up 344 SQ only AW456874 0.215122 1.281268 0.00392 1.79125 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 1419717_at 20349 Sema3e 3 - up 344 SQ only (semaphorin) 3E 0.263448 0.829477 0.00402 1.790405 RIKEN cDNA 1455786_at 628054 2610036F08Ri 3 - up 344 SQ only 2610036F08 gene 0.957778 1.011558 0.00271 1.786824 RIKEN cDNA 1453166_at 215999 D130073L02Ri3 - up 344 SQ only D130073L02 gene 0.786529 0.972602 0.00022 1.785117 Wiskott-Aldrich syndrome protein 1436953_at 215280 Waspip 3 - up 344 SQ only interacting protein 0.277794 1.23317 0.00086 1.783318 RIKEN cDNA 1436132_at 320706 9830001H06Ri3 - up 344 SQ only 9830001H06 gene 0.632437 0.915056 0.00563 1.782433

solute carrier family 9 (sodium/hydrogen exchanger), member 1417397_at 20544 Slc9a1 3 - up 344 SQ only 1 0.774277 1.024759 0.00322 1.780623

DnaJ (Hsp40) homolog, subfamily 1425076_at 76594 Dnajc18 3 - up 344 SQ only C, member 18 0.234199 1.2193 0.00176 1.778165 transmembrane 1436499_at 208449 Tmem23 3 - up 344 SQ only protein 23 0.093058 1.184819 0.0008 1.777884 MON1 homolog A 1428898_at 72825 Mon1a 3 - up 344 SQ only (yeast) 0.079029 1.197488 0.00083 1.776527 RIKEN cDNA 1456587_x_at 72046 2010005J08Rik3 - up 344 SQ only 2010005J08 gene 0.01582 1.252204 0.00111 1.77617 RIKEN cDNA 1428535_at 240185 9430020K01Ri 3 - up 344 SQ only 9430020K01 gene 0.20649 1.325694 0.00912 1.776106 1427203_at 217328 Myo15b 3 - up 344 SQ only myosin XVB 0.977583 1.009681 0.00681 1.77474 RIKEN cDNA 1424058_at 73137 1190002C06Ri3 - up 344 SQ only 1190002C06 gene 0.971988 1.001868 0.00241 1.773103 Jumonji domain 1440368_at 193796 Jmjd2b 3 - up 344 SQ only containing 2B 0.0994 1.300878 0.00622 1.77285 RIKEN cDNA 1429652_at 73137 1190002C06Ri3 - up 344 SQ only 1190002C06 gene 0.033776 1.230238 0.00051 1.771659 1426802_at 20362 39699 3 - up 344 SQ only septin 8 0.175637 1.224342 0.00082 1.769801

thioredoxin domain 1453120_at 52837 Txndc13 3 - up 344 SQ only containing 13 0.003124 1.290003 0.00262 1.767729 neighbor of Punc 1416474_at 56741 Nope 3 - up 344 SQ only E11 0.131682 1.249354 0.0025 1.766811 FUS interacting protein (serine- 1418526_at 14105 Fusip1 3 - up 344 SQ only arginine rich) 1 0.362281 1.127347 0.0038 1.766707 ubiquitin specific 1448013_at 329908 Usp24 3 - up 344 SQ only peptidase 24 0.477687 1.099731 0.0001 1.755899 fatty acid desaturase 1435910_at 60527 Fads3 3 - up 344 SQ only 3 0.60992 0.904798 0.00885 1.755161 hypothetical gene 1425775_at 75424 MGC29393 3 - up 344 SQ only MGC29393 0.984965 1.044498 0.00026 1.753124

peroxisome proliferator activated 1420715_a_at 19016 Pparg 3 - up 344 SQ only receptor gamma 0.297636 0.878656 0.0003 1.751226 1457670_s_at 16905 Lmna 3 - up 344 SQ only lamin A 0.167543 1.131775 0.00026 1.749682 Rab6 interacting 1424015_at 19347 Rab6ip1 3 - up 344 SQ only protein 1 0.280173 1.146551 8.9E-05 1.743856 1426022_a_at 22351 Vill 3 - up 344 SQ only villin-like 0.092531 1.270842 0.00623 1.741611

adaptor-related protein complex AP- 1416307_at 11767 Ap1m1 3 - up 344 SQ only 1, mu subunit 1 0.311021 1.118577 0.00126 1.741005

0 day neonate kidney cDNA, RIKEN full-length enriched library, clone:D630029P09 product:unclassifiabl e, full insert 1455468_at ------3 - up 344 SQ only sequence 0.577544 1.075454 0.00454 1.737665 RIKEN cDNA 1431103_at 75890 1700003P14Ri 3 - up 344 SQ only 1700003P14 gene 0.046562 1.292936 0.00712 1.736787 RIKEN cDNA 1434675_at 73451 1700065O13R 3 - up 344 SQ only 1700065O13 gene 0.218065 1.175962 0.00337 1.734893 1423091_a_at 14758 Gpm6b 3 - up 344 SQ only glycoprotein m6b 0.224978 1.211391 0.00554 1.733933 Bcl6 interacting 1429438_at 71458 Bcor 3 - up 344 SQ only corepressor 0.056615 1.319366 0.00146 1.730728 1455090_at 26360 Angptl2 3 - up 344 SQ only angiopoietin-like 2 0.43024 1.153443 0.00616 1.729725 Lysosomal acid 1423141_at 16889 Lip1 3 - up 344 SQ only lipase 1 0.234397 1.144086 0.006 1.729047 1433754_at 105559 Mbnl2 3 - up 344 SQ only muscleblind-like 2 0.334755 0.872751 0.00081 1.729009 signal peptidase complex subunit 3 homolog (S. 1451175_at 76687 Spcs3 3 - up 344 SQ only cerevisiae) 0.24878 1.242681 0.00128 1.727815 transmembrane 1433802_at 381199 Tmem151 3 - up 344 SQ only protein 151 0.378399 1.097597 0.00523 1.727047 large tumor 1439441_x_at 50523 Lats2 3 - up 344 SQ only suppressor 2 0.848734 1.022408 0.00714 1.726717 sprouty homolog 4 1445669_at 24066 Spry4 3 - up 344 SQ only (Drosophila) 0.518252 0.922756 0.00255 1.726145

ring finger and KH 1454612_at 240396 Rkhd2 3 - up 344 SQ only domain containing 2 0.741695 1.038323 0.00272 1.717174 golgi phosphoprotein 1415698_at 105348 Golph2 3 - up 344 SQ only 2 0.060387 0.864229 2.9E-05 1.715133

solute carrier family 1422788_at 58207 Slc43a3 3 - up 344 SQ only 43, member 3 0.488335 1.145797 0.00685 1.713698

schwannomin 1423025_a_at 30953 Schip1 3 - up 344 SQ only interacting protein 1 0.635605 1.057251 0.006 1.711768 1435222_at 108655 Foxp1 3 - up 344 SQ only forkhead box P1 0.282947 1.200972 0.00211 1.710806 cAMP responsive element binding 1437396_at 208647 Creb3l2 3 - up 344 SQ only protein 3-like 2 0.775635 0.942648 0.00628 1.710162

trinucleotide repeat 1436982_at 213988 Tnrc6b 3 - up 344 SQ only containing 6b 0.216692 1.163441 0.00298 1.709671 RIKEN cDNA 1427879_at 69171 1810031K17Ri 3 - up 344 SQ only 1810031K17 gene 0.004803 1.269904 0.00254 1.709277 zinc finger protein 1430558_at 57908 Zfp318 3 - up 344 SQ only 318 0.084369 1.251612 0.0012 1.708013 1453228_at 74732 Stx11 3 - up 344 SQ only syntaxin 11 0.775874 0.983664 0.00163 1.706113

mindbomb homolog 1454740_at 225164 Mib1 3 - up 344 SQ only 1 (Drosophila) 0.124742 1.178881 0.00032 1.705117 similar to PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains 1427475_a_at 669660 LOC669660 3 - up 344 SQ only protein) 0.440817 0.896138 0.00143 1.704411 hydroxysteroid 11- beta dehydrogenase 1449038_at 15483 Hsd11b1 3 - up 344 SQ only 1 0.504427 0.914357 0.00558 1.703175 PRA1 domain family 1416782_s_at 54637 Praf2 3 - up 344 SQ only 2 0.884624 0.986203 0.00275 1.702974 1454795_at 319876 Cobll1 3 - up 344 SQ only Cobl-like 1 0.9672 1.001993 0.00631 1.701642 GATA zinc finger domain containing 1455505_at 234366 Gatad2a 3 - up 344 SQ only 2A 0.022122 1.296638 0.00073 1.70113

scavenger receptor 1460235_at 12492 Scarb2 3 - up 344 SQ only class B, member 2 0.108385 1.185063 0.00049 1.70051 brain glycogen 1433504_at 110078 Pygb 3 - up 344 SQ only phosphorylase 0.627922 1.086027 0.00983 1.699486 RIKEN cDNA 1436734_at 272031 E130309F12Ri3 - up 344 SQ only E130309F12 gene 0.925199 1.084767 0.00594 1.699194 zinc finger and BTB domain containing 1439128_at 56490 Zbtb20 3 - up 344 SQ only 20 0.735228 1.035643 0.0088 1.698758 RIKEN cDNA 1457260_at 100224 7530403E16Ri 3 - up 344 SQ only 7530403E16 gene 0.220512 1.307528 0.00099 1.697783 Autophagy-related 7 1446418_at 74244 Atg7 3 - up 344 SQ only (yeast) 0.965403 1.023582 0.00024 1.696347 chimerin (chimaerin) 1428574_a_at 69993 Chn2 3 - up 344 SQ only 2 0.74323 1.040394 0.00844 1.693514 cDNA sequence 1455793_at 212326 BC035537 3 - up 344 SQ only BC035537 0.818793 1.186365 0.00098 1.69259 chimerin (chimaerin) 1428573_at 69993 Chn2 3 - up 344 SQ only 2 0.474912 0.90268 0.00607 1.689456 1455591_at ------3 - up 344 SQ only --- 0.137621 0.851634 9.5E-05 1.685311 RIKEN cDNA 1428824_at 76425 2310003C23Ri3 - up 344 SQ only 2310003C23 gene 0.158648 0.829875 0.00307 1.685002 cDNA sequence 1437475_at 407833 BC028454 3 - up 344 SQ only BC028454 0.002894 1.246886 2.9E-05 1.683257 SH3-domain binding protein 5 (BTK- 1421923_at 24056 Sh3bp5 3 - up 344 SQ only associated) 0.165496 1.217103 0.00543 1.682293 nuclear factor of activated T-cells, cytoplasmic, calcineurin- 1428479_at 18018 Nfatc1 3 - up 344 SQ only dependent 1 0.041095 1.223876 0.00172 1.680896 zinc finger protein 1437237_x_at 65020 Zfp110 3 - up 344 SQ only 110 0.105213 1.172333 0.00025 1.678653 1435374_at ------3 - up 344 SQ only Transcribed locus 0.56363 1.140922 0.00056 1.676431

ankyrin repeat and SOCS box- 1434961_at 65247 Asb1 3 - up 344 SQ only containing protein 1 0.90541 0.988014 0.00132 1.675541 v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived 1434777_at 16918 Mycl1 3 - up 344 SQ only (avian) 0.970686 1.046229 0.00593 1.675204 1428749_at 235380 Dmxl2 3 - up 344 SQ only Dmx-like 2 0.712092 0.950689 0.00976 1.673006 arrestin domain 1454617_at 105171 Arrdc3 3 - up 344 SQ only containing 3 0.55391 1.1231 0.00757 1.672904

transforming, acidic coiled-coil containing 1425745_a_at 57752 Tacc2 3 - up 344 SQ only protein 2 0.251524 1.080748 0.00014 1.671971 Rab38, member of RAS oncogene 1441774_at 72433 Rab38 3 - up 344 SQ only family 0.091743 1.264472 0.00303 1.671255

chloride intracellular channel 4 1438606_a_at 29876 Clic4 3 - up 344 SQ only (mitochondrial) 0.618576 0.936791 0.00162 1.668386 PRA1 domain family 1416781_at 54637 Praf2 3 - up 344 SQ only 2 0.940526 1.05809 0.00158 1.665286 selenophosphate 1449040_a_at 20768 Sephs2 3 - up 344 SQ only synthetase 2 0.147874 1.282616 0.00792 1.664842 ATPase, Ca++ transporting, plasma 1445679_at 320707 Atp2b3 3 - up 344 SQ only membrane 3 0.560631 1.257139 0.00031 1.663939 cDNA sequence 1439423_x_at 228801 U46068 3 - up 344 SQ only U46068 0.662736 0.918496 0.00808 1.663884

Rho-associated coiled-coil containing 1450994_at 19877 Rock1 3 - up 344 SQ only protein kinase 1 0.97214 1.007771 0.00256 1.663113

solute carrier family 7 (cationic amino acid transporter, y+ 1447181_s_at 20540 Slc7a7 3 - up 344 SQ only system), member 7 0.255529 1.089663 0.00081 1.662262 l(3)mbt-like 3 1454882_at 237339 L3mbtl3 3 - up 344 SQ only (Drosophila) 0.568869 1.09506 0.00952 1.661621 coiled-coil domain 1439109_at 381175 Ccdc68 3 - up 344 SQ only containing 68 0.862201 0.996246 0.00436 1.658673 RIKEN cDNA 1438382_x_at 72046 2010005J08Rik3 - up 344 SQ only 2010005J08 gene 0.333188 1.210949 0.00092 1.657584 1435450_at 70568 Cpne3 3 - up 344 SQ only copine III 0.045584 1.213895 0.00012 1.656857 procollagen, type V, 1419703_at 53867 Col5a3 3 - up 344 SQ only alpha 3 0.84749 1.009372 0.00268 1.655517

DnaJ (Hsp40) homolog, subfamily 1433887_at 19107 Dnajc3 3 - up 344 SQ only C, member 3 0.786892 0.978559 0.00709 1.653743

S- adenosylhomocystei 1426830_a_at 229709 Ahcyl1 3 - up 344 SQ only ne hydrolase-like 1 0.061224 1.241503 0.00267 1.649248 spermatogenesis 1437865_at 219140 Spata13 3 - up 344 SQ only associated 13 0.25381 1.185229 0.00594 1.647396

F-box and leucine- 1454635_at 50789 Fbxl3 3 - up 344 SQ only rich repeat protein 3 0.438919 1.085904 0.0027 1.644718

kelch-like 2, Mayven 1426978_at 77113 Klhl2 3 - up 344 SQ only (Drosophila) 0.471869 0.913911 0.00481 1.643746 diacylglycerol 1418578_at 13139 Dgka 3 - up 344 SQ only kinase, alpha 0.570863 0.969436 0.00016 1.643645 1455418_at ------3 - up 344 SQ only Transcribed locus 0.864751 1.090888 0.00609 1.64322 RIKEN cDNA 1428195_at 74340 4631427C17Ri3 - up 344 SQ only 4631427C17 gene 0.844962 1.02624 0.00193 1.642592

DnaJ (Hsp40) homolog, subfamily 1418591_at 58233 Dnaja4 3 - up 344 SQ only A, member 4 0.575943 0.953443 0.0005 1.642264 fibroblast growth 1450869_at 14164 Fgf1 3 - up 344 SQ only factor 1 0.181507 0.954015 0.00049 1.641706

testicular cell 1435410_at 75870 Tcam1 3 - up 344 SQ only adhesion molecule 1 0.143089 1.246058 0.00734 1.641079 zinc finger protein 1450998_at 65020 Zfp110 3 - up 344 SQ only 110 0.963028 1.017356 0.00412 1.641023 procollagen, type 1429549_at 373864 Col27a1 3 - up 344 SQ only XXVII, alpha 1 0.5659 1.115827 0.0067 1.640573

golgi associated, gamma adaptin ear containing, ARF 1428141_at 74105 Gga2 3 - up 344 SQ only binding protein 2 0.114895 1.233719 0.00619 1.637776

S100 calcium 1418704_at 20196 S100a13 3 - up 344 SQ only binding protein A13 0.331202 1.089472 0.00214 1.634954 chitobiase, di-N- 1429943_at 74245 Ctbs 3 - up 344 SQ only acetyl- 0.173541 1.262538 0.00872 1.63295 zinc finger protein 1437236_a_at 65020 Zfp110 3 - up 344 SQ only 110 0.432008 1.142385 0.00072 1.631825 1436984_at 329165 Abi2 3 - up 344 SQ only abl-interactor 2 0.300736 1.18496 0.002 1.629737

teashirt zinc finger 1435385_at 228911 Tshz2 3 - up 344 SQ only family member 2 0.908683 1.049155 0.00131 1.628679 praja 2, RING-H2 1434383_at 224938 Pja2 3 - up 344 SQ only motif containing 0.167128 1.274032 0.00611 1.628532

phosphatidic acid 1429514_at 67916 Ppap2b 3 - up 344 SQ only phosphatase type 2B 0.37848 0.884236 0.00927 1.62756

ring finger (C3HC4 type) and KH domain 1437627_at 237400 Rkhd1 3 - up 344 SQ only containing 1 0.213298 1.298198 0.00647 1.627546 1415737_at 54391 Rfk 3 - up 344 SQ only riboflavin kinase 0.974268 1.017044 0.00262 1.627118 fibronectin type III domain containing 1433833_at 72007 Fndc3b 3 - up 344 SQ only 3B 0.443242 1.140679 0.00425 1.624082

SEC24 related gene family, member A (S. 1433934_at 77371 Sec24a 3 - up 344 SQ only cerevisiae) 0.478304 1.080179 0.00449 1.623375 solute carrier family 19 (thiamine transporter), member 1417902_at 116914 Slc19a2 3 - up 344 SQ only 2 0.055732 1.254378 0.00504 1.617555 1417850_at 19645 Rb1 3 - up 344 SQ only retinoblastoma 1 0.56228 1.09451 3E-05 1.617113 unc-5 homolog B (C. 1435110_at 107449 Unc5b 3 - up 344 SQ only elegans) 0.156708 1.142056 0.00264 1.614934

myristoylated alanine rich protein kinase C 1415971_at 17118 Marcks 3 - up 344 SQ only substrate 0.527688 0.917706 0.00577 1.614826 dihydrolipoamide branched chain 1449118_at 13171 Dbt 3 - up 344 SQ only transacylase E2 0.467179 1.087144 0.00339 1.613323 bone morphogenic protein receptor, type II (serine/threonine 1434310_at 12168 Bmpr2 3 - up 344 SQ only kinase) 0.150541 1.15834 4.5E-05 1.613236 1436994_a_at 50708 Hist1h1c 3 - up 344 SQ only histone 1, H1c 0.725569 0.967841 0.00098 1.611069 thioesterase superfamily member 1427055_at 75778 Them4 3 - up 344 SQ only 4 0.043812 1.235889 0.0041 1.609605 expressed sequence 1460406_at 102502 AI427122 3 - up 344 SQ only AI427122 0.907501 1.049089 0.00928 1.609 ubiquitin specific 1448014_s_at 329908 Usp24 3 - up 344 SQ only peptidase 24 0.972161 0.999403 0.00137 1.605618 dihydropyrimidinase- 1438789_s_at 22240 Dpysl3 3 - up 344 SQ only like 3 0.947676 1.017865 0.00052 1.605077 AF4/FMR2 family, 1450031_at 93736 Aff4 3 - up 344 SQ only member 4 0.309314 1.08211 0.00013 1.60254 calcitonin receptor- 1425814_a_at 54598 Calcrl 3 - up 344 SQ only like 0.897523 1.039007 0.00683 1.600422 Adult retina cDNA, RIKEN full-length enriched library, clone:A930031I16 product:unclassifiabl e, full insert 1442205_at ------3 - up 344 SQ only sequence 0.254188 1.180224 0.00426 1.600147 RIKEN cDNA 1450496_a_at 66468 2810433K01Ri 3 - up 344 SQ only 2810433K01 gene 0.673277 0.958136 0.0064 1.59924 jumonji, AT rich interactive domain 1452562_at 20592 Jarid1d 3 - up 344 SQ only 1D (Rbp2 like) 0.508642 1.157244 0.00866 1.597061 selenoprotein P, 1452141_a_at 20363 Sepp1 3 - up 344 SQ only plasma, 1 0.698638 0.959602 0.00098 1.596302

topoisomerase I binding, 1417755_at 106021 Topors 3 - up 344 SQ only arginine/serine-rich 0.820757 1.022721 0.00527 1.596092

acetyl-Coenzyme A 1424183_at 110446 Acat1 3 - up 344 SQ only acetyltransferase 1 0.022928 1.248865 0.00443 1.591894 RNA binding motif 1456058_at 225432 Rbm27 3 - up 344 SQ only protein 27 0.674547 1.028266 0.00763 1.589767 glutamate 1448253_at 14661 Glud1 3 - up 344 SQ only dehydrogenase 1 0.478309 1.090482 0.00696 1.589515 RNA binding protein gene with multiple 1429359_s_at 19663 Rbpms 3 - up 344 SQ only splicing 0.726966 0.97664 8.6E-05 1.586992 methyltransferase 1434151_at 70152 Mettl7a 3 - up 344 SQ only like 7A 0.295978 0.890728 0.00209 1.58648 cDNA sequence 1455437_at 70661 BC033915 3 - up 344 SQ only BC033915 0.592159 1.093345 0.00047 1.586378 transmembrane BAX inhibitor motif 1417162_at 69660 Tmbim1 3 - up 344 SQ only containing 1 0.439278 1.166918 0.00212 1.58278

Nedd4 family 1424821_at 65113 Ndfip1 3 - up 344 SQ only interacting protein 1 0.337864 1.112671 0.00073 1.58221

histone 2, H3c1 /// histone 2, H2aa1 /// histone 1, H2ad /// histone 1, H2an /// histone 2, H2ab /// histone 2, H2ac /// 1418367_x_at 15077 /// Hist2h3c1 /// H 3 - up 344 SQ only histone 2, H2aa2 0.57334 1.031286 0.00049 1.582091 1441927_at 54525 Syt7 3 - up 344 SQ only Synaptotagmin VII 0.046384 1.19009 0.00086 1.578453 1437685_x_at 14264 Fmod 3 - up 344 SQ only fibromodulin 0.462283 1.168702 0.00783 1.576988

ATP-binding cassette, sub-family C (CFTR/MRP), 1438056_x_at 27416 Abcc5 3 - up 344 SQ only member 5 0.444288 1.06224 0.00107 1.576955

solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), 1455069_x_at 11739 Slc25a4 3 - up 344 SQ only member 4 0.058704 1.203947 0.00082 1.575419 1452752_at 56401 Lepre1 3 - up 344 SQ only leprecan 1 0.248755 1.141421 0.00343 1.575355 RIKEN cDNA 1420809_a_at 56398 1500003O03R 3 - up 344 SQ only 1500003O03 gene 0.309736 1.138165 0.00684 1.574721

1438067_at 18015 Nf1 3 - up 344 SQ only neurofibromatosis 1 0.070652 1.241531 0.00314 1.574384

low density lipoprotein receptor- related protein 1452148_at 16976 Lrpap1 3 - up 344 SQ only associated protein 1 0.094375 1.139505 0.00822 1.570976 alkaline phosphatase, 1431077_at 76768 Alpi 3 - up 344 SQ only intestinal 0.564284 0.950471 0.00908 1.569652 cytoplasmic polyadenylation element binding 1455372_at 208922 Cpeb3 3 - up 344 SQ only protein 3 0.626108 0.931264 0.00936 1.569091 RIKEN cDNA 1439292_at 73652 2210408F21Ri 3 - up 344 SQ only 2210408F21 gene 0.095295 1.178965 0.00431 1.566145 kinesin family 1418428_at 16573 Kif5b 3 - up 344 SQ only member 5B 0.561683 0.947319 0.00372 1.564174 1423736_a_at 69190 Dym 3 - up 344 SQ only dymeclin 0.450154 1.130891 0.00544 1.563486

solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), 1424562_a_at 11739 Slc25a4 3 - up 344 SQ only member 4 0.0638 1.205083 0.00129 1.562422 RIKEN cDNA 1430516_at 73854 4930428B01Ri 3 - up 344 SQ only 4930428B01 gene 0.745118 1.05628 0.00463 1.561441 nuclear factor, erythroid derived 2, 1416543_at 18024 Nfe2l2 3 - up 344 SQ only like 2 0.65914 1.044641 7.5E-06 1.55858 carnitine palmitoyltransferase 1434866_x_at 12894 Cpt1a 3 - up 344 SQ only 1a, liver 0.295914 1.208436 5.2E-05 1.557788 acyl-CoA 1439478_at 171210 Acot2 3 - up 344 SQ only thioesterase 2 0.08044 1.138693 0.00211 1.555841 RAB34, member of RAS oncogene 1416591_at 19376 Rab34 3 - up 344 SQ only family 0.310379 1.229196 0.0025 1.555387 abhydrolase domain 1418661_at 54608 Abhd2 3 - up 344 SQ only containing 2 0.262134 0.886464 0.00138 1.552739 RIKEN cDNA 1448648_at 68303 9130005N14Ri3 - up 344 SQ only 9130005N14 gene 0.930419 1.001855 0.00518 1.551613

protein phosphatase 1, regulatory (inhibitor) subunit 1437735_at 17931 Ppp1r12a 3 - up 344 SQ only 12A 0.049797 1.203212 0.00574 1.550849 SET binding protein 1458575_at 240427 Setbp1 3 - up 344 SQ only 1 0.365131 1.105167 0.00026 1.55076 RIKEN cDNA 1427985_at 270624 9630042H07Ri3 - up 344 SQ only 9630042H07 gene 0.85302 1.048849 0.00082 1.550256 chondroitin sulfate 1424431_at 78752 Galnact2 3 - up 344 SQ only GalNAcT-2 0.974242 1.042604 0.00065 1.549788 transcription factor 1437174_at 211586 Tfdp2 3 - up 344 SQ only Dp 2 0.065255 0.876112 0.00054 1.549647 1421002_at 26360 Angptl2 3 - up 344 SQ only angiopoietin-like 2 0.598544 1.101147 0.00862 1.545581 progestin and adipoQ receptor 1444468_at 74229 Paqr8 3 - up 344 SQ only family member VIII 0.506936 1.101869 0.00686 1.54516 RIKEN cDNA 1454898_s_at 67732 4833421E05Ri 3 - up 344 SQ only 4833421E05 gene 0.416047 1.133118 0.00119 1.544076 phosphatidylinositol membrane- 1438974_x_at 18739 Pitpnm1 3 - up 344 SQ only associated 1 0.273441 1.156845 0.00864 1.54046 RIKEN cDNA 1417272_at 68303 9130005N14Ri3 - up 344 SQ only 9130005N14 gene 0.77283 0.987578 8E-05 1.538829 HERPUD family 1439424_x_at 80517 Herpud2 3 - up 344 SQ only member 2 0.502195 1.23974 0.00683 1.538134

Notch gene homolog 1455556_at 18129 Notch2 3 - up 344 SQ only 2 (Drosophila) 0.447926 1.057712 0.00563 1.537214 centrosomal protein 1437154_at 545389 Cep170 3 - up 344 SQ only 170 0.402264 1.122156 0.00279 1.536294 SEC22 vesicle trafficking protein homolog B (S. 1415766_at 20333 Sec22b 3 - up 344 SQ only cerevisiae) 0.158487 1.184644 0.00824 1.532226 nuclear receptor coactivator 4 /// similar to nuclear receptor coactivator 1420808_at 27057 /// Ncoa4 /// LOC63 - up 344 SQ only 4 0.5344 0.928817 0.00493 1.528549 elongation factor 1460643_at 13716 Ell 3 - up 344 SQ only RNA polymerase II 0.617396 1.058397 0.00605 1.52825

DnaJ (Hsp40) homolog, subfamily 1442182_at 67713 Dnajc19 3 - up 344 SQ only C, member 19 0.943478 1.033331 0.00062 1.528122 protein inhibitor of 1428725_at 17344 Pias2 3 - up 344 SQ only activated STAT 2 0.466605 1.066629 0.00881 1.527988 RIKEN cDNA 1424072_at 69894 2010107G23R 3 - up 344 SQ only 2010107G23 gene 0.182139 1.146879 0.00351 1.527762 solute carrier family 17 (anion/sugar transporter), member 1429116_at 235504 Slc17a5 3 - up 344 SQ only 5 0.051733 1.222818 0.00178 1.526519 coiled-coil domain 1442982_at 320234 Ccdc66 3 - up 344 SQ only containing 66 0.650644 1.051717 0.00756 1.5261 RIKEN cDNA 1451483_s_at 73420 1700054N08Ri3 - up 344 SQ only 1700054N08 gene 0.482358 1.077066 0.00635 1.526014 1431566_at ------3 - up 344 SQ only --- 0.869224 0.989224 0.00497 1.525808 RIKEN cDNA 1429065_at 67454 1200009F10Ri 3 - up 344 SQ only 1200009F10 gene 0.116083 1.205731 0.00098 1.524866

1424706_at 22709 Zfp51 3 - up 344 SQ only zinc finger protein 51 0.854873 1.056847 0.00262 1.52478

target of EGR1, 1432207_a_at 68276 Toe1 3 - up 344 SQ only member 1 (nuclear) 0.505673 1.047189 0.00323 1.522976 SET domain, 1451833_a_at 84505 Setdb1 3 - up 344 SQ only bifurcated 1 0.833935 0.977025 0.00813 1.522225

Adult male medulla oblongata cDNA, RIKEN full-length enriched library, clone:6330531L09 product:unclassifiabl e, full insert 1440325_at ------3 - up 344 SQ only sequence 0.816964 1.026145 0.00014 1.52081

acyl-Coenzyme A 1416409_at 11430 Acox1 3 - up 344 SQ only oxidase 1, palmitoyl 0.254638 1.212683 0.00489 1.519864 ELK4, member of ETS oncogene 1427162_a_at 13714 Elk4 3 - up 344 SQ only family 0.271449 1.165717 0.00132 1.518135 leucine rich repeat and fibronectin type III domain containing 1456767_at 233067 Lrfn3 3 - up 344 SQ only 3 0.898082 1.010377 0.0047 1.517527 WW domain containing transcription 1417818_at 97064 Wwtr1 3 - up 344 SQ only regulator 1 0.456354 1.065738 0.00317 1.517066

potassium channel tetramerisation domain containing 1423694_at 330171 Kctd10 3 - up 344 SQ only 10 0.739216 1.023641 0.00949 1.516449

Myristoylated alanine rich protein kinase C 1456028_x_at 17118 Marcks 3 - up 344 SQ only substrate 0.599571 0.935208 0.00711 1.515793 transmembrane 1448396_at 56030 Tmem131 3 - up 344 SQ only protein 131 0.032723 1.191396 0.00237 1.515083 protein tyrosine phosphatase, 1418540_a_at 19267 Ptpre 3 - up 344 SQ only receptor type, E 0.860147 0.998953 0.00028 1.509206 progestin and adipoQ receptor 1428958_at 74229 Paqr8 3 - up 344 SQ only family member VIII 0.234973 1.121058 0.00624 1.508075 platelet-activating factor acetylhydrolase, isoform 1b, alpha2 1422793_at 18475 Pafah1b2 3 - up 344 SQ only subunit 0.608225 1.091974 0.00608 1.506815 ADP-ribosylation 1431429_a_at 11861 Arl4a 3 - up 344 SQ only factor-like 4A 0.155656 1.13132 0.00573 1.502627 1455333_at 319939 Tns3 3 - up 344 SQ only tensin 3 0.190151 1.152046 0.00385 1.501843 polyhomeotic-like 3 1455312_at 241915 Phc3 3 - up 344 SQ only (Drosophila) 0.317386 1.059493 0.00281 1.500691 carnitine palmitoyltransferase 1438156_x_at 12894 Cpt1a 3 - up 344 SQ only 1a, liver 0.273587 1.202736 5.3E-06 1.500398 1425601_a_at 20166 Rtkn 4 - down 344 SQ only rhotekin 0.757861 1.034239 0.00703 0.666849

dihydrolipoamide S- acetyltransferase (E2 component of pyruvate dehydrogenase 1426265_x_at 235339 Dlat 4 - down 344 SQ only complex) 0.377687 1.165586 0.00192 0.66645 RIKEN cDNA 1427897_s_at 71954 2400003N08Ri4 - down 344 SQ only 2400003N08 gene 0.40938 0.935818 0.00215 0.666238 Parkinson disease (autosomal recessive, early 1456194_a_at 57320 Park7 4 - down 344 SQ only onset) 7 0.511118 0.937313 0.00418 0.665928 mitochondrial ribosomal protein 1453728_a_at 66258 Mrps17 4 - down 344 SQ only S17 0.333533 0.91997 0.00198 0.665862

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 1450818_a_at 66416 Ndufa7 4 - down 344 SQ only (B14.5a) 0.110693 0.846056 0.00352 0.665726

mannose-6- phosphate receptor, 1416385_a_at 17113 M6pr 4 - down 344 SQ only cation dependent 0.016441 0.90009 0.00037 0.665714 E2F transcription 1417878_at 13555 E2f1 4 - down 344 SQ only factor 1 0.843005 0.97818 0.00783 0.665554 phosphodiesterase 1458218_s_at 18583 Pde7a 4 - down 344 SQ only 7A 0.856977 0.989431 0.00234 0.66547 triggering receptor expressed on 1421792_s_at 83433 Trem2 4 - down 344 SQ only myeloid cells 2 0.688672 0.953846 0.00509 0.665336

dihydrolipoamide S- acetyltransferase (E2 component of pyruvate dehydrogenase 1426264_at 235339 Dlat 4 - down 344 SQ only complex) 0.352167 1.169679 0.00304 0.665255

silica-induced gene 111 /// HCLS1 1438180_x_at 20461 /// Silg111 /// Hax 4 - down 344 SQ only associated X-1 0.137289 0.923407 0.00052 0.665233 RIKEN cDNA 1424211_at 70556 5730438N18Ri4 - down 344 SQ only 5730438N18 gene 0.563784 1.06291 0.00123 0.665192 minichromosome maintenance deficient 2 mitotin (S. 1434079_s_at 17216 Mcm2 4 - down 344 SQ only cerevisiae) 0.337948 0.923193 5.5E-05 0.664707 topoisomerase 1442454_at 21973 Top2a 4 - down 344 SQ only (DNA) II alpha 0.918458 1.005691 0.00987 0.664499 adaptor protein complex AP-1, 1419113_at 11766 Ap1g2 4 - down 344 SQ only gamma 2 subunit 0.366719 1.125681 0.00431 0.664499

endoplasmic 1453634_a_at 67397 Erp29 4 - down 344 SQ only reticulum protein 29 0.923917 1.003938 0.00121 0.664094 cDNA sequence 1436543_at 207704 BC034507 4 - down 344 SQ only BC034507 0.407263 0.899561 0.00233 0.663764 postmeiotic segregation increased 2 (S. 1423539_at 18861 Pms2 4 - down 344 SQ only cerevisiae) 0.057876 0.836524 0.00452 0.663706 1430520_at 66871 Cpne8 4 - down 344 SQ only copine VIII 0.965683 1.000635 0.00015 0.662585 coenzyme Q2 homolog, prenyltransferase 1452791_at 71883 Coq2 4 - down 344 SQ only (yeast) 0.744485 0.971421 0.00093 0.662262

minichromosome maintenance deficient 4 homolog 1416214_at 17217 Mcm4 4 - down 344 SQ only (S. cerevisiae) 0.606285 1.064783 0.00376 0.661568

1455843_at 14345 Fut4 4 - down 344 SQ only fucosyltransferase 4 0.880437 1.085906 0.00073 0.661421 cleavage and polyadenylation 1417665_a_at 94230 Cpsf1 4 - down 344 SQ only specific factor 1 0.078612 0.824668 0.0027 0.66026 G protein-coupled 1460276_a_at 24100 Gpr175 4 - down 344 SQ only receptor 175 0.495674 0.938085 0.00849 0.660193 male enhanced 1437943_s_at 17256 Mea1 4 - down 344 SQ only antigen 1 0.060291 0.818161 0.0006 0.659893 uridine-cytidine 1424646_at 68556 Uckl1 4 - down 344 SQ only kinase 1-like 1 0.144616 0.8968 0.0012 0.659734

erythrocyte protein 1425199_a_at 226352 Epb4.1l5 4 - down 344 SQ only band 4.1-like 5 0.334298 1.154054 0.00021 0.65953 polymerase (RNA) III (DNA directed) 1424227_at 78929 Polr3h 4 - down 344 SQ only polypeptide H 0.289371 0.931287 0.00147 0.659289 procollagen, type 1447819_x_at 12837 Col8a1 4 - down 344 SQ only VIII, alpha 1 0.561074 0.925062 0.00983 0.658735

small nuclear 1452680_at 107686 Snrpd2 4 - down 344 SQ only ribonucleoprotein D2 0.148834 0.892313 0.00658 0.65861 steroid 5 alpha- 1439241_x_at 57357 Srd5a2l 4 - down 344 SQ only reductase 2-like 0.962452 0.99563 0.00385 0.658605 inner membrane protein, 1433470_a_at 76614 Immt 4 - down 344 SQ only mitochondrial 0.073682 0.859691 4.4E-05 0.657974 RIKEN cDNA 1450972_at 67290 3110040N11Ri4 - down 344 SQ only 3110040N11 gene 0.712747 1.039202 0.00307 0.657413 1427707_a_at ------4 - down 344 SQ only --- 0.24979 0.859197 0.00568 0.657283

similar to gonadotropin inducible ovarian 1440202_at 622175 LOC622175 4 - down 344 SQ only transcription factor 2 0.467743 0.905698 0.00686 0.656323

prolyl endopeptidase- 1452034_at 213760 Prepl 4 - down 344 SQ only like 0.47978 1.084016 0.0039 0.656281

minichromosome maintenance deficient 3 (S. cerevisiae) /// similar to DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme- associated protein 1449705_x_at 17215 /// Mcm3 /// LOC64 - down 344 SQ only P1) (P1-MCM3) 1 1.000451 0.0069 0.655937 FGFR1 oncogene 1431020_a_at 67529 Fgfr1op2 4 - down 344 SQ only partner 2 0.057012 0.894946 0.00051 0.655595 dynamin binding 1427033_at 71972 Dnmbp 4 - down 344 SQ only protein 0.284144 1.146971 0.00494 0.655297 XPA binding protein 1417390_at 74254 Xab1 4 - down 344 SQ only 1 0.437691 0.93022 0.00216 0.655074 1454896_at ------4 - down 344 SQ only --- 0.686273 1.018677 0.00024 0.655046 G protein-coupled 1451672_at 26385 Gprk6 4 - down 344 SQ only receptor kinase 6 0.636561 0.944293 0.00626 0.655041 DEAD (Asp-Glu-Ala- Asp) box polypeptide 1416751_a_at 53975 Ddx20 4 - down 344 SQ only 20 0.708728 0.980383 0.00074 0.6544 1435155_at 70737 Cgn 4 - down 344 SQ only cingulin 0.933225 1.028372 0.00233 0.654196

solute carrier family 7 (cationic amino acid transporter, y+ 1426068_at 224022 Slc7a4 4 - down 344 SQ only system), member 4 0.984099 1.004289 0.00043 0.65386

1416585_at 56505 Ruvbl1 4 - down 344 SQ only RuvB-like protein 1 0.155086 1.142151 0.00053 0.653205 NADH dehydrogenase (ubiquinone) Fe-S 1433603_at 407785 Ndufs6 4 - down 344 SQ only protein 6 0.243642 0.882703 0.00722 0.652919

cytochrome c 1448112_at 12867 Cox7c 4 - down 344 SQ only oxidase, subunit VIIc 0.217613 0.864047 0.00924 0.651699 RIKEN cDNA 1451471_at 67417 3230401I01Rik4 - down 344 SQ only 3230401I01 gene 0.843193 1.026312 0.0006 0.651638 1450722_at 18141 Nup50 4 - down 344 SQ only nucleoporin 50 0.022081 0.81984 0.0024 0.650599 RAB19, member RAS oncogene 1430148_at 19331 Rab19 4 - down 344 SQ only family 0.263287 0.885384 0.00076 0.650474 DNA segment, Chr 13, Wayne State University 177, 1424620_at 28126 D13Wsu177e 4 - down 344 SQ only expressed 0.480796 1.058828 0.00357 0.650368

UDP-N-acetyl-alpha- D- galactosamine:polyp eptide N- acetylgalactosaminyl transferase 3 /// hypothetical protein 1417589_at 14425 /// Galnt3 /// LOC64 - down 344 SQ only LOC620893 0.909922 1.032271 0.00131 0.649927 coiled-coil domain 1419812_s_at 52469 Ccdc56 4 - down 344 SQ only containing 56 0.206688 0.895208 0.00275 0.649734 steroid 5 alpha- 1456691_s_at 57357 Srd5a2l 4 - down 344 SQ only reductase 2-like 0.929921 0.98605 0.00314 0.649665

BMS1-like, ribosome assembly protein 1433636_at 213895 Bms1l 4 - down 344 SQ only (yeast) 0.718423 1.06627 0.00971 0.649465 growth factor receptor bound 1448227_at 14786 Grb7 4 - down 344 SQ only protein 7 0.434975 0.89119 0.00522 0.649025 coiled-coil domain 1423840_at 52469 Ccdc56 4 - down 344 SQ only containing 56 0.986893 0.990258 0.00972 0.649014

RIKEN cDNA 1451668_at 215015 C530043G21R4 - down 344 SQ only C530043G21 gene 0.487184 0.930727 0.00011 0.648998 RIKEN cDNA 1420642_a_at 67067 2010100O12R 4 - down 344 SQ only 2010100O12 gene 0.01955 0.813582 0.00377 0.648858 RIKEN cDNA 1433342_at 70550 5730416F02Ri 4 - down 344 SQ only 5730416F02 gene 0.968012 1.024088 0.00551 0.648034 RIKEN cDNA 2610005L07 gene /// RIKEN cDNA A430108E01 gene /// similar to p47 1437717_x_at 381598 // 2610005L07Ri 4 - down 344 SQ only protein isoform a 0.550688 1.138411 0.00434 0.647861

Heterogeneous nuclear 1446083_at 11991 Hnrpd 4 - down 344 SQ only ribonucleoprotein D 0.175875 0.865225 0.00212 0.647807

thyroid hormone receptor associated 1448917_at 69790 Thrap6 4 - down 344 SQ only protein 6 0.00902 0.866903 0.00112 0.647228

cyclic nucleotide 1437341_x_at 12799 Cnp1 4 - down 344 SQ only phosphodiesterase 1 0.108673 1.172078 0.00529 0.646896 1422489_at 57377 Gcs1 4 - down 344 SQ only glucosidase 1 0.446758 1.102458 0.00387 0.646367 shugoshin-like 1 (S. 1418919_at 72415 Sgol1 4 - down 344 SQ only pombe) 0.318031 0.90938 0.00108 0.645897 TBC1 domain family, 1456792_at 381605 Tbc1d2 4 - down 344 SQ only member 2 0.393743 0.874035 0.00793 0.645242 phosphatidylinositol glycan anchor 1428556_at 66459 Pigy 4 - down 344 SQ only biosynthesis, class Y 0.413126 0.884669 0.00968 0.644609 neutrophil cytosolic 1418465_at 17972 Ncf4 4 - down 344 SQ only factor 4 0.137248 0.828201 0.0077 0.644443

DNA topoisomerase 1460370_at 72960 Top1mt 4 - down 344 SQ only 1, mitochondrial 0.12085 0.865419 0.0021 0.644147 RIKEN cDNA 1455384_x_at 225995 D030056L22Ri4 - down 344 SQ only D030056L22 gene 0.468549 1.08481 0.00037 0.644059 1419639_at 13642 Efnb2 4 - down 344 SQ only ephrin B2 0.39647 0.891431 0.00173 0.642222

Zwilch, kinetochore associated, homolog 1416757_at 68014 Zwilch 4 - down 344 SQ only (Drosophila) 0.574397 0.930722 0.00458 0.64082 1419298_at 269823 Pon3 4 - down 344 SQ only paraoxonase 3 0.143775 0.83817 0.00538 0.640534

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 1428360_x_at 66416 Ndufa7 4 - down 344 SQ only (B14.5a) 0.091819 0.830282 0.00382 0.640286 Bcl2-associated 1423948_at 213539 Bag2 4 - down 344 SQ only athanogene 2 0.980994 1.035583 0.00153 0.640235

small nucleolar RNA, 1435655_at 104367 Snora65 4 - down 344 SQ only H/ACA box 65 0.599515 0.951421 0.00176 0.639913 ribonucleotide 1415878_at 20133 Rrm1 4 - down 344 SQ only reductase M1 0.133688 0.833289 0.00173 0.638999 RIKEN cDNA 1432358_at 73732 1110008I14Rik4 - down 344 SQ only 1110008I14 gene 0.476203 1.049587 0.00648 0.638968 mitochondrial ribosomal protein 1452111_at 232536 Mrps35 4 - down 344 SQ only S35 0.389734 1.087763 3.9E-05 0.638948 Kruppel-like factor 1416029_at 21847 Klf10 4 - down 344 SQ only 10 0.317 0.862963 0.0036 0.638583 G protein-coupled 1437436_s_at 26385 Gprk6 4 - down 344 SQ only receptor kinase 6 0.267784 0.933006 0.00066 0.63826 nephronophthisis 1 (juvenile) homolog 1448523_at 53885 Nphp1 4 - down 344 SQ only (human) 0.4297 1.090965 0.00759 0.637901 testis expressed 1434317_s_at 269536 Tex10 4 - down 344 SQ only gene 10 0.049948 0.835467 0.0028 0.637511 ATPase, H+ transporting, lysosomal V1 1419545_a_at 66335 Atp6v1c1 4 - down 344 SQ only subunit C1 0.269083 0.88298 2.7E-06 0.636812

ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A- 1456917_at 211673 Arfgef1 4 - down 344 SQ only inhibited) 0.269929 0.869674 0.00265 0.636623

expressed sequence 1426996_at 105732 AA409316 4 - down 344 SQ only AA409316 0.484083 0.920194 0.00133 0.636366 RIKEN cDNA 1447578_at 73486 1700084J12Rik4 - down 344 SQ only 1700084J12 gene 0.312656 1.158204 0.00967 0.636028 RIKEN cDNA 1451283_at 67726 1810073G14R 4 - down 344 SQ only 1810073G14 gene 0.947872 0.991311 0.00599 0.635712 polymerase (RNA) II (DNA directed) 1415754_at 69833 Polr2f 4 - down 344 SQ only polypeptide F 0.071795 0.805696 0.00167 0.635623

PRP31 pre-mRNA processing factor 31 1448633_at 68988 Prpf31 4 - down 344 SQ only homolog (yeast) 0.212779 1.093978 0.0027 0.635437

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 1436567_a_at 66416 Ndufa7 4 - down 344 SQ only (B14.5a) 0.084137 0.828761 0.0027 0.634774

minichromosome maintenance deficient 3 (S. cerevisiae) /// similar to DNA replication licensing factor MCM3 (DNA polymerase alpha holoenzyme- associated protein 1420028_s_at 17215 /// Mcm3 /// LOC64 - down 344 SQ only P1) (P1-MCM3) 0.775789 1.040488 0.0062 0.634188 eukaryotic translation initiation factor 4E binding 1417562_at 13685 Eif4ebp1 4 - down 344 SQ only protein 1 0.66996 1.046954 0.0089 0.634077 capping protein (actin filament), 1450355_a_at 12332 Capg 4 - down 344 SQ only gelsolin-like 0.830636 0.990203 0.00393 0.633682

H2A histone family, member J /// similar to H2A histone family, member J 1424771_at 232440 // H2afj /// LOC634 - down 344 SQ only isoform 2 0.248969 1.186777 0.00696 0.633246

DnaJ (Hsp40) homolog, subfamily 1448794_s_at 22791 Dnajc2 4 - down 344 SQ only C, member 2 0.874456 0.994879 0.00383 0.632892

nuclear RNA export factor 1 homolog (S. 1439092_at 53319 Nxf1 4 - down 344 SQ only cerevisiae) 0.441885 0.898863 0.00996 0.632414 nudix (nucleoside diphosphate linked moiety X)-type motif 1418737_at 66401 Nudt2 4 - down 344 SQ only 2 0.948128 1.013012 0.00406 0.632213 small nuclear ribonucleoprotein polypeptide G /// similar to small nuclear ribonucleoprotein polypeptide G /// similar to small nuclear ribonucleoprotein 1448357_at 666609 // Snrpg /// LOC64 - down 344 SQ only polypeptide G 0.23016 0.843311 0.00753 0.631855 peptidylprolyl isomerase F 1416940_at 105675 Ppif 4 - down 344 SQ only (cyclophilin F) 0.439425 0.924786 0.00124 0.630625 RIKEN cDNA 1456520_at 268469 9530033F24Ri 4 - down 344 SQ only 9530033F24 gene 0.428692 0.930931 0.00154 0.630542 coiled-coil domain 1449083_at 67015 Ccdc91 4 - down 344 SQ only containing 91 0.653958 1.043775 0.00229 0.630141

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 1422976_x_at 66416 Ndufa7 4 - down 344 SQ only (B14.5a) 0.143253 0.827082 0.00637 0.629749 sterile alpha motif domain containing 1435756_at 229011 Samd10 4 - down 344 SQ only 10 0.464046 0.940415 0.00173 0.629641

src family associated 1418895_at 54353 Scap2 4 - down 344 SQ only phosphoprotein 2 0.600714 1.030083 9.9E-05 0.629111 hemopoietic cell 1449455_at 15162 Hck 4 - down 344 SQ only kinase 0.613845 0.941093 0.00578 0.628972 RIKEN cDNA 1424496_at 75731 5133401N09Ri4 - down 344 SQ only 5133401N09 gene 0.230588 1.140725 0.0036 0.628515 ATPase, H+ transporting, lysosomal V1 1419546_at 66335 Atp6v1c1 4 - down 344 SQ only subunit C1 0.313115 0.896704 5.7E-06 0.628361 mutS homolog 6 (E. 1416915_at 17688 Msh6 4 - down 344 SQ only coli) 0.399761 1.130658 0.00367 0.628357 RIKEN cDNA 1417840_at 66994 1500031L02Ri 4 - down 344 SQ only 1500031L02 gene 0.773951 0.973034 0.0041 0.626949 1448026_at ------4 - down 344 SQ only --- 0.078236 0.81203 0.00118 0.626922

RAD51 associated 1417938_at 19362 Rad51ap1 4 - down 344 SQ only protein 1 0.201797 0.886621 0.00148 0.625337 mitochondrial ribosomal protein 1449004_at 67308 Mrpl46 4 - down 344 SQ only L46 0.556284 0.944372 0.00181 0.624426 THUMP domain 1417684_at 14911 Thumpd3 4 - down 344 SQ only containing 3 0.51443 1.067859 0.00017 0.624406

8-oxoguanine DNA- 1448815_at 18294 Ogg1 4 - down 344 SQ only glycosylase 1 0.247539 0.848126 0.00374 0.624354 B-cell leukemia/lymphoma 1437122_at 12043 Bcl2 4 - down 344 SQ only 2 0.548281 1.089778 0.00992 0.623651 solute carrier family 1435483_x_at 69906 Slc25a32 4 - down 344 SQ only 25, member 32 0.623047 0.948546 0.0025 0.623418

ubiquitin-conjugating enzyme E2F 1451272_a_at 67921 Ube2f 4 - down 344 SQ only (putative) 0.399929 0.885423 0.00485 0.622313

Rho guanine nucleotide exchange 1421164_a_at 16801 Arhgef1 4 - down 344 SQ only factor (GEF) 1 0.036395 0.802976 0.00014 0.622179 adenylosuccinate 1418372_at 11564 Adsl 4 - down 344 SQ only lyase 0.887323 0.991303 0.00857 0.622109 mitochondrial ribosomal protein 1418716_at 64658 Mrps25 4 - down 344 SQ only S25 0.191718 1.170965 0.00135 0.622081 mitochondrial ribosomal protein 1460354_a_at 68537 Mrpl13 4 - down 344 SQ only L13 0.134213 0.840333 0.00219 0.621425

BCL2-like 11 1456005_a_at 12125 Bcl2l11 4 - down 344 SQ only (apoptosis facilitator) 0.75929 0.953851 0.00939 0.620942 RIKEN cDNA 1436317_at 241062 D230012E17R 4 - down 344 SQ only D230012E17 gene 0.928503 1.202419 0.0055 0.620681 germ cell-less homolog 1 1417113_at 23885 Gmcl1 4 - down 344 SQ only (Drosophila) 0.846179 0.988199 0.00063 0.620473 left right determination factor 1417638_at 13590 Lefty1 4 - down 344 SQ only 1 0.75786 0.978613 0.00047 0.619788 IBR domain 1439153_at 218215 Ibrdc2 4 - down 344 SQ only containing 2 0.597072 0.956352 0.00198 0.61893 homer homolog 1 1437363_at 26556 Homer1 4 - down 344 SQ only (Drosophila) 0.376477 0.913974 0.00162 0.618076 polyamine oxidase 1428859_at 212503 Paox 4 - down 344 SQ only (exo-N4-amino) 0.150059 1.132039 0.00523 0.618034 RIKEN cDNA 1448685_at 67267 2900010M23R 4 - down 344 SQ only 2900010M23 gene 0.087849 0.820801 0.00178 0.617889

Tnf receptor- 1424320_a_at 224619 Traf7 4 - down 344 SQ only associated factor 7 0.264762 0.845158 0.00816 0.617302 RIKEN cDNA 1425146_at 223648 2410075B13Ri 4 - down 344 SQ only 2410075B13 gene 0.01125 0.784634 0.00422 0.61701

Rho GTPase 1426952_at 73910 Arhgap18 4 - down 344 SQ only activating protein 18 0.285833 0.82983 0.00326 0.616016 RIKEN cDNA 1419357_at 57905 5830446M03R 4 - down 344 SQ only 5830446M03 gene 0.25026 1.13276 0.00134 0.615978 glutaredoxin 2 1437680_x_at 69367 Glrx2 4 - down 344 SQ only (thioltransferase) 0.688933 1.020894 0.00016 0.615855 GINS complex subunit 4 (Sld5 1417913_at 109145 Gins4 4 - down 344 SQ only homolog) 0.505171 1.106491 0.00124 0.615821

vesicle-associated 1437708_x_at 22319 Vamp3 4 - down 344 SQ only membrane protein 3 0.168843 0.814465 0.00188 0.614607 pyrroline-5- carboxylate reductase family, 1448315_a_at 69051 Pycr2 4 - down 344 SQ only member 2 0.048957 1.187594 0.00249 0.614193 protein tyrosine phosphatase, non- 1455450_at 545622 Ptpn3 4 - down 344 SQ only receptor type 3 0.297332 0.877365 9E-05 0.61317 RIKEN cDNA 1453173_at 67861 2310005E10Ri 4 - down 344 SQ only 2310005E10 gene 0.045931 0.833455 0.00146 0.613112 mitochondrial ribosomal protein 1421914_s_at 56284 Mrpl19 4 - down 344 SQ only L19 0.171232 1.192127 0.00032 0.612582 BUD31 homolog 1433611_s_at 231889 Bud31 4 - down 344 SQ only (yeast) 0.022157 0.850351 0.00162 0.612572

solute carrier family 1453149_at 69906 Slc25a32 4 - down 344 SQ only 25, member 32 0.072459 0.860818 0.00283 0.612178

cytoplasmic tyrosine kinase, Dscr28C 1460204_at 21682 Tec 4 - down 344 SQ only related (Drosophila) 0.535889 0.926615 0.00147 0.611198

trans-acting 1448994_at 20683 Sp1 4 - down 344 SQ only transcription factor 1 0.175228 0.831716 0.00794 0.611065 zinc finger CCHC- type and RNA 1428489_at 67197 Zcrb1 4 - down 344 SQ only binding motif 1 0.268989 0.811948 0.00658 0.611032 coiled-coil and C2 domain containing 1433861_at 319965 Cc2d1b 4 - down 344 SQ only 1B 0.156659 0.853253 0.00046 0.610597 RIKEN cDNA 1416438_at 67959 2410104I19Rik4 - down 344 SQ only 2410104I19 gene 0.05022 0.817135 0.00028 0.610462 SHQ1 homolog (S. 1444485_at 72171 Shq1 4 - down 344 SQ only cerevisiae) 0.62919 0.945953 0.00486 0.610237 ligand dependent nuclear receptor 1455260_at 209707 Lcorl 4 - down 344 SQ only corepressor-like 0.464941 0.903911 0.00202 0.609862 makorin, ring finger 1455504_a_at 54484 Mkrn1 4 - down 344 SQ only protein, 1 0.401775 1.117255 0.003 0.609539

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 1455749_x_at 66416 Ndufa7 4 - down 344 SQ only (B14.5a) 0.09034 0.824884 0.00299 0.609514 neural precursor cell expressed, developmentally down-regulated gene 1423269_a_at 83814 Nedd4l 4 - down 344 SQ only 4-like 0.12275 0.850086 0.0057 0.609241 PAX interacting (with transcription- activation domain) 1423302_a_at 55982 Paxip1 4 - down 344 SQ only protein 1 0.700405 1.044365 0.00077 0.608729

acyl-CoA synthetase long-chain family 1451828_a_at 50790 Acsl4 4 - down 344 SQ only member 4 0.875058 1.093886 0.00392 0.60776 enabled homolog 1431162_a_at 13800 Enah 4 - down 344 SQ only (Drosophila) 0.543225 0.917973 0.00349 0.607429 nucleolar complex associated 4 homolog (S. 1443794_x_at 100608 Noc4l 4 - down 344 SQ only cerevisiae) 0.56786 1.11041 0.00989 0.606185

splicing factor, 1438674_a_at 231769 Sfrs8 4 - down 344 SQ only arginine/serine-rich 8 0.698428 0.966072 0.00163 0.605733 RIKEN cDNA 1415714_a_at 66618 2610209M04R 4 - down 344 SQ only 2610209M04 gene 0.208561 0.848169 0.00435 0.605528 glutaredoxin 2 1422998_a_at 69367 Glrx2 4 - down 344 SQ only (thioltransferase) 0.441893 0.948345 0.00015 0.605343 thyroid hormone receptor interactor 1429295_s_at 69716 Trip13 4 - down 344 SQ only 13 0.188802 0.872043 0.00604 0.605319 1438394_x_at 16682 Krt4 4 - down 344 SQ only keratin 4 0.461656 0.913499 0.00044 0.605208 Tumor necrosis factor (ligand) superfamily, member 1445227_at 69583 Tnfsf13 4 - down 344 SQ only 13 0.765996 0.9903 0.00133 0.604677 cytotoxic granule- associated RNA 1431708_a_at 21841 Tia1 4 - down 344 SQ only binding protein 1 0.295252 0.866795 0.00591 0.604302 similar to dual specificity 1427416_x_at 674944 LOC674944 4 - down 344 SQ only phosphatase 7 0.49496 1.20748 0.00933 0.603607

expressed sequence 1435326_at 98667 AW112037 4 - down 344 SQ only AW112037 0.716068 1.06138 0.00064 0.603008 steroid 5 alpha- 1438699_at 78925 Srd5a1 4 - down 344 SQ only reductase 1 0.14032 0.818403 0.00336 0.602871 mitochondrial ribosomal protein 1427173_a_at 14548 Mrps33 4 - down 344 SQ only S33 0.569204 0.941651 0.00269 0.602183

sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, 1459903_at 20361 Sema7a 4 - down 344 SQ only (semaphorin) 7A 0.418761 1.131148 0.0024 0.601581 BUD31 homolog 1439466_s_at 231889 Bud31 4 - down 344 SQ only (yeast) 0.308493 0.882457 0.00271 0.601466 sex comb on midleg 1426241_a_at 29871 Scmh1 4 - down 344 SQ only homolog 1 0.229742 1.188106 9E-05 0.600236

single-stranded DNA 1427965_at 381760 Ssbp1 4 - down 344 SQ only binding protein 1 0.425572 0.916078 0.00126 0.599833 SFT2 domain 1425027_s_at 108735 Sft2d2 4 - down 344 SQ only containing 2 0.106132 0.837946 0.00121 0.599438

1423560_at 54003 Nell2 4 - down 344 SQ only NEL-like 2 (chicken) 0.285282 0.823998 0.00543 0.599171

zinc finger, HIT 1425531_at 70103 Znhit1 4 - down 344 SQ only domain containing 1 0.065343 0.839197 0.00221 0.599023

endothelial precursor 1417596_at 27078 Eppb9 4 - down 344 SQ only protein B9 0.823186 1.017106 0.00846 0.597644 TCDD-inducible poly(ADP-ribose) 1426721_s_at 99929 Tiparp 4 - down 344 SQ only polymerase 0.774883 0.978698 0.00612 0.59722

ubiquinol- cytochrome c reductase, complex 1430326_s_at 22272 Uqcrq 4 - down 344 SQ only III subunit VII 0.373442 0.877071 0.00494 0.59647

Fc receptor, IgE, high affinity I, 1418340_at 14127 Fcer1g 4 - down 344 SQ only gamma polypeptide 0.244938 0.826437 0.00529 0.596351 RIKEN cDNA 1426797_at 72649 2700094F01Ri 4 - down 344 SQ only 2700094F01 gene 0.186675 0.875071 1.4E-05 0.5963 transmembrane 1452219_at 224807 Tmem63b 4 - down 344 SQ only protein 63b 0.508039 0.929253 0.0007 0.595995 LPS-responsive 1449099_at 80877 Lrba 4 - down 344 SQ only beige-like anchor 0.572351 0.941514 0.00079 0.593677 RIKEN cDNA 1432701_at 69960 2810403G07R 4 - down 344 SQ only 2810403G07 gene 0.342641 0.903485 0.00773 0.593574 jumonji domain 1426810_at 104263 Jmjd1a 4 - down 344 SQ only containing 1A 0.139711 0.85681 0.00096 0.593091 RIKEN cDNA 1432570_at 77881 6030458E02Ri 4 - down 344 SQ only 6030458E02 gene 0.180679 0.796879 0.00841 0.592217 glutaredoxin 2 1437679_a_at 69367 Glrx2 4 - down 344 SQ only (thioltransferase) 0.826862 0.985556 0.00034 0.592066 RIKEN cDNA 1417807_at 70240 2700038N03Ri4 - down 344 SQ only 2700038N03 gene 0.518107 0.936988 0.00045 0.591553 glycoprotein A33 1419330_a_at 59290 Gpa33 4 - down 344 SQ only (transmembrane) 0.720347 0.963369 0.00188 0.590744

methyltransferase 10 1453983_a_at 67493 Mett10d 4 - down 344 SQ only domain containing 0.533675 1.107147 0.00384 0.59073 1441971_at ------4 - down 344 SQ only Transcribed locus 0.475115 1.176537 0.00345 0.590611 G protein-coupled receptor 31, 1452408_at 436440 Gpr31c 4 - down 344 SQ only D17Leh66c region 0.806354 0.98502 0.00033 0.588975

RIKEN cDNA 1434322_at 231830 A930021H16R 4 - down 344 SQ only A930021H16 gene 0.363668 1.1237 0.00087 0.588607 EMG1 nucleolar protein homolog (S. 1416393_at 14791 Emg1 4 - down 344 SQ only cerevisiae) 0.327239 0.947744 0.0002 0.587881

RIKEN cDNA 1419824_a_at 231326 A230062G08R 4 - down 344 SQ only A230062G08 gene 0.754074 1.052069 0.00728 0.587162

erythrocyte protein 1434575_at 13821 Epb4.1l1 4 - down 344 SQ only band 4.1-like 1 0.613355 0.917218 0.00821 0.586182 ATX1 (antioxidant protein 1) homolog 1 1460639_a_at 11927 Atox1 4 - down 344 SQ only (yeast) 0.198971 0.851142 0.00397 0.585669 MAP kinase- activated protein 1417016_at 17165 Mapkapk5 4 - down 344 SQ only kinase 5 0.328539 0.89304 0.00025 0.585348 GrpE-like 1, 1417320_at 17713 Grpel1 4 - down 344 SQ only mitochondrial 0.094804 0.883018 0.00133 0.585098 phosphatidylinositol- 4-phosphate 5- 1426009_a_at 18720 Pip5k1b 4 - down 344 SQ only kinase, type 1 beta 0.574137 0.911715 0.00919 0.584945 midasin homolog 1417675_a_at 100019 Mdn1 4 - down 344 SQ only (yeast) 0.911623 0.98607 0.00484 0.584877

proline-rich Gla (G- carboxyglutamic 1424329_a_at 65116 Prrg2 4 - down 344 SQ only acid) polypeptide 2 0.033657 0.773545 0.00078 0.584511

1449418_s_at 66153 Fbxo36 4 - down 344 SQ only F-box only protein 36 0.449091 0.915035 4.1E-05 0.583309 RIKEN cDNA 1428684_at 68971 1500001M20R 4 - down 344 SQ only 1500001M20 gene 0.46569 0.933479 0.00097 0.582974 1430359_a_at 78914 Nadsyn1 4 - down 344 SQ only NAD synthetase 1 0.674699 0.947855 0.0051 0.582107 helicase, lymphoid 1417541_at 15201 Hells 4 - down 344 SQ only specific 0.841694 0.985343 0.00304 0.581578 cyclin-dependent kinase inhibitor 1A 1424638_at 12575 Cdkn1a 4 - down 344 SQ only (P21) 0.072496 0.793507 0.00312 0.581465

RAN GTPase 1423749_s_at 19387 Rangap1 4 - down 344 SQ only activating protein 1 0.259226 0.890115 0.00026 0.58128

1417775_at 20019 Rpo1-4 4 - down 344 SQ only RNA polymerase 1-4 0.433261 0.921649 0.00058 0.58127 1433781_a_at 64945 Cldn12 4 - down 344 SQ only claudin 12 0.042974 0.767495 0.00555 0.581223

1448747_at 67731 Fbxo32 4 - down 344 SQ only F-box only protein 32 0.251993 0.843389 0.00391 0.58108 mitochondrial ribosomal protein 1451307_at 68463 Mrpl14 4 - down 344 SQ only L14 0.201434 0.901305 0.00036 0.580447 cDNA sequence 1434365_a_at 381306 BC055324 4 - down 344 SQ only BC055324 0.032674 0.807345 0.00963 0.580383 myeloid/lymphoid or mixed lineage- leukemia translocation to 4 homolog 1436303_at 17356 Mllt4 4 - down 344 SQ only (Drosophila) 0.39401 0.91174 0.0005 0.580321 polymerase (DNA- directed), epsilon 4 1423372_at 66979 Pole4 4 - down 344 SQ only (p12 subunit) 0.115152 0.870001 2.7E-05 0.580131 1419638_at 13642 Efnb2 4 - down 344 SQ only ephrin B2 0.137473 0.847115 0.00033 0.579886 1423924_s_at 52588 Tspan14 4 - down 344 SQ only tetraspanin 14 0.011747 0.774268 0.0001 0.579567

1452661_at 22042 Tfrc 4 - down 344 SQ only transferrin receptor 0.76446 1.245862 0.00282 0.579359

pleckstrin homology domain containing, 1455343_at 233765 Plekha7 4 - down 344 SQ only family A member 7 0.46947 1.055364 0.00073 0.57809 RIKEN cDNA 1449056_at 243780 E330009J07Ri 4 - down 344 SQ only E330009J07 gene 0.0597 0.816246 0.00526 0.577898 replication factor C 1452917_at 72151 Rfc5 4 - down 344 SQ only (activator 1) 5 0.049394 0.846553 0.00092 0.577022 serine hydroxymethyl transferase 1 1425179_at 20425 Shmt1 4 - down 344 SQ only (soluble) 0.510786 1.21408 0.00969 0.576895 sarcoglycan, beta (dystrophin- associated 1419668_at 24051 Sgcb 4 - down 344 SQ only glycoprotein) 0.556755 0.952707 0.0051 0.576257 steroid 5 alpha- 1454649_at 78925 Srd5a1 4 - down 344 SQ only reductase 1 0.178493 0.843141 0.00023 0.575013 heme binding protein 1418917_at 56016 Hebp2 4 - down 344 SQ only 2 0.834175 1.0357 0.00167 0.574604

lymphocyte antigen 1453304_s_at 17069 Ly6e 4 - down 344 SQ only 6 complex, locus E 0.262767 0.856338 0.00153 0.573251

zinc finger, HIT 1451745_a_at 70103 Znhit1 4 - down 344 SQ only domain containing 1 0.122321 0.837301 0.00278 0.573162 3-oxoacid CoA 1449059_a_at 67041 Oxct1 4 - down 344 SQ only transferase 1 0.807693 1.023999 0.00396 0.57249

recombining binding protein suppressor of hairless 1418114_at 19664 Rbpsuh 4 - down 344 SQ only (Drosophila) 0.02579 0.818357 9.4E-08 0.572444

retinitis pigmentosa GTPase regulator 1421144_at 77945 Rpgrip1 4 - down 344 SQ only interacting protein 1 0.020025 0.76512 0.00063 0.571972 mitogen activated protein kinase kinase kinase kinase 1428297_at 26412 Map4k2 4 - down 344 SQ only 2 0.924521 1.023163 0.00076 0.571752

mitochondrial 1450948_a_at 94061 Mrpl1 4 - down 344 SQ only ribosomal protein L1 0.163853 0.903873 0.00414 0.571149

par-6 (partitioning defective 6) homolog 1423174_a_at 58220 Pard6b 4 - down 344 SQ only beta (C. elegans) 0.145821 0.785289 0.00158 0.57081 mitochondrial ribosomal protein 1424204_at 68537 Mrpl13 4 - down 344 SQ only L13 0.014298 0.853944 4.2E-06 0.570283 RAS p21 protein 1426477_at 218397 Rasa1 4 - down 344 SQ only activator 1 0.434507 0.868164 0.00819 0.56985

ubiquitin-conjugating 1452954_at 68612 Ube2c 4 - down 344 SQ only enzyme E2C 0.062772 0.775988 0.00485 0.569531 regulator of G- 1417601_at 50778 Rgs1 4 - down 344 SQ only protein signaling 1 0.450172 1.16711 0.00175 0.569202 microtubule associated serine/threonine kinase family 1437404_at 328329 Mast4 4 - down 344 SQ only member 4 0.49964 1.110746 0.00729 0.568638 14, 17 days embryo head cDNA, RIKEN full-length enriched library, clone:3222402J19 product:unclassifiabl e, full insert 1455145_at ------4 - down 344 SQ only sequence 0.319597 0.923118 0.00025 0.568219 pterin 4 alpha carbinolamine dehydratase/dimeriz ation cofactor of hepatocyte nuclear factor 1 alpha 1452621_at 72562 Pcbd2 4 - down 344 SQ only (TCF1) 2 0.289192 0.827692 0.00697 0.567937

protein kinase, AMP- activated, gamma 2 1451140_s_at 108099 Prkag2 4 - down 344 SQ only non-catalytic subunit 0.137461 0.887181 0.00022 0.566899

1451323_at 223669 Zfp7 4 - down 344 SQ only zinc finger protein 7 0.332542 0.848167 0.00329 0.566131 RIKEN cDNA 1428495_at 75593 2410003K15Ri 4 - down 344 SQ only 2410003K15 gene 0.050176 0.789745 0.00026 0.565576 RAS p21 protein 1417333_at 54153 Rasa4 4 - down 344 SQ only activator 4 0.516792 0.901485 0.00607 0.565267 1456387_at 319211 Nol4 4 - down 344 SQ only nucleolar protein 4 0.196136 0.819827 0.00081 0.56526 nudix (nucleoside diphosphate linked moiety X)-type motif 1449349_at 17766 Nudt1 4 - down 344 SQ only 1 0.944347 1.005942 2.7E-05 0.56522 gene model 1313, 1426619_at 383619 Gm1313 4 - down 344 SQ only (NCBI) 0.918528 1.003783 1E-06 0.564557 1444479_at ------4 - down 344 SQ only --- 0.936572 1.046728 0.00796 0.563135 ribonuclease III, 1428656_at 14000 Rnasen 4 - down 344 SQ only nuclear 0.296306 0.882729 0.00311 0.562498 RIKEN cDNA 1423767_at 66310 2810410M20R 4 - down 344 SQ only 2810410M20 gene 0.208252 0.855976 0.00224 0.561898 1421997_s_at 16400 Itga3 4 - down 344 SQ only integrin alpha 3 0.95106 1.016494 0.00067 0.561862 zinc finger protein 1437483_at 101023 Zfp513 4 - down 344 SQ only 513 0.02392 0.790754 0.00114 0.561672 1459640_at ------4 - down 344 SQ only --- 0.600264 0.905142 0.00691 0.561484

RIKEN cDNA 1454766_at 232566 C730024G19R4 - down 344 SQ only C730024G19 gene 0.085961 0.815829 0.00079 0.561466 RIKEN cDNA 1447828_x_at 67484 2310005P05Ri 4 - down 344 SQ only 2310005P05 gene 0.684471 0.965289 0.00504 0.560676 replication factor C 1457669_x_at 19718 Rfc2 4 - down 344 SQ only (activator 1) 2 0.240876 0.8717 0.00229 0.560564 sarcoglycan, beta (dystrophin- associated 1419667_at 24051 Sgcb 4 - down 344 SQ only glycoprotein) 0.021225 0.758138 0.00206 0.560396 RIKEN cDNA 1451975_at 67238 2810453I06Rik4 - down 344 SQ only 2810453I06 gene 0.986847 0.999659 0.00076 0.559529 RIKEN cDNA 1455794_at 276829 D130058I21Rik4 - down 344 SQ only D130058I21 gene 0.477043 0.909458 0.00025 0.558803 RIKEN cDNA 1432969_at 71157 4933423K11Ri 4 - down 344 SQ only 4933423K11 gene 0.083444 0.77434 0.00558 0.558098 tripartite motif 1448101_s_at 19720 Trim27 4 - down 344 SQ only protein 27 0.420213 1.243834 0.00018 0.555877 RIKEN cDNA 1452904_at 69987 1700026L06Ri 4 - down 344 SQ only 1700026L06 gene 0.254919 0.81559 0.00471 0.555432 hypoxia inducible factor 3, alpha 1446708_at 53417 Hif3a 4 - down 344 SQ only subunit 0.611196 1.007046 0.00178 0.554953 RIKEN cDNA 1428771_at 76788 2410127E18Ri 4 - down 344 SQ only 2410127E18 gene 0.172654 0.802265 0.00332 0.553293

phosphatidylinositol glycan anchor 1425134_a_at 72084 Pigx 4 - down 344 SQ only biosynthesis, class X 0.252675 1.094861 0.00016 0.553145

actin related protein 2/3 complex, subunit 1452044_at 74192 Arpc5l 4 - down 344 SQ only 5-like 0.738286 1.036902 0.00164 0.55215 nudix (nucleoside diphosphate linked moiety X)-type motif 1449107_at 71207 Nudt4 4 - down 344 SQ only 4 0.50749 0.917425 0.00681 0.552015 poliovirus receptor- 1424456_at 19294 Pvrl2 4 - down 344 SQ only related 2 0.084609 0.786642 0.00088 0.551343 ATPase, H+ transporting, lysosomal V1 1423993_at 66144 Atp6v1f 4 - down 344 SQ only subunit F 0.359657 0.913596 0.00055 0.55134 FK506 binding 1416362_a_at 14228 Fkbp4 4 - down 344 SQ only protein 4 0.73108 1.067988 0.00013 0.551121 Fc receptor, IgG, 1436625_at 14129 Fcgr1 4 - down 344 SQ only high affinity I 0.227979 0.874874 0.00161 0.551025 makorin, ring finger 1451425_a_at 54484 Mkrn1 4 - down 344 SQ only protein, 1 0.703264 1.113025 0.00061 0.550496 protein phosphatase 1453127_at 71887 Ppm1j 4 - down 344 SQ only 1J 0.76626 0.980793 0.00045 0.550137 RIKEN cDNA 1424861_at 100662 D930016D06R 4 - down 344 SQ only D930016D06 gene 0.189862 0.777632 0.00508 0.54929 cytoskeleton associated protein 2- 1453769_at 70466 Ckap2l 4 - down 344 SQ only like 0.169495 0.787572 0.00667 0.549021 Capping protein (actin filament), 1447803_x_at 12332 Capg 4 - down 344 SQ only gelsolin-like 0.619943 0.978371 0.00314 0.548983 histone deacetylase 1451229_at 232232 Hdac11 4 - down 344 SQ only 11 0.915173 1.07644 0.00253 0.548787

solute carrier family 23 (nucleobase transporters), 1460042_at 22626 Slc23a3 4 - down 344 SQ only member 3 0.55209 0.925367 0.00684 0.548644

major facilitator superfamily domain 1428223_at 76574 Mfsd2 4 - down 344 SQ only containing 2 0.888458 1.051592 0.00464 0.548601 aldo-keto reductase 1423556_at 11997 Akr1b7 4 - down 344 SQ only family 1, member B7 0.875588 1.038601 0.00038 0.548256 cadherin EGF LAG seven-pass G-type 1422073_a_at 53883 Celsr2 4 - down 344 SQ only receptor 2 0.617735 0.950468 0.00024 0.548256 ubiquitin specific 1424866_at 216835 Usp43 4 - down 344 SQ only peptidase 43 0.569831 0.921392 0.00426 0.547844 melanoma antigen, 1422498_at 75625 Mageh1 4 - down 344 SQ only family H, 1 0.572424 0.925686 0.00196 0.547186 zinc finger protein 1455975_x_at 81018 Zfp313 4 - down 344 SQ only 313 0.305751 0.889604 0.00398 0.546976 interleukin 17 1426566_s_at 57890 Il17re 4 - down 344 SQ only receptor E 0.004773 0.828044 0.00012 0.546752

FGF receptor 1424615_at 233575 Frag1 4 - down 344 SQ only activating protein 1 0.034382 0.842132 0.00053 0.545957 TCF3 (E2A) fusion 1438963_s_at 69714 Tfpt 4 - down 344 SQ only partner 0.564163 1.067093 0.00358 0.545122 Collagen and calcium binding EGF 1440053_at 320924 Ccbe1 4 - down 344 SQ only domains 1 0.328874 0.818161 0.00594 0.544744 PWWP domain 1438417_at 101631 Pwwp2 4 - down 344 SQ only containing 2 0.618675 0.957002 3.4E-05 0.544578

ATP synthase, H+ transporting, mitochondrial F1F0 1434053_x_at 11958 Atp5k 4 - down 344 SQ only complex, subunit e 0.074782 0.795713 0.00346 0.542789 furry homolog 1457131_at 320365 Fry 4 - down 344 SQ only (Drosophila) 0.230772 0.788269 0.00496 0.542371 serine/threonine 1455183_at 232533 Stk38l 4 - down 344 SQ only kinase 38 like 0.075507 0.756656 0.00026 0.541461 RIKEN cDNA 1449412_at 103742 1810046J19Rik4 - down 344 SQ only 1810046J19 gene 0.125216 0.764707 0.00211 0.539857 Ral GEF with PH domain and SH3 1417230_at 78255 Ralgps2 4 - down 344 SQ only binding motif 2 0.010334 0.749302 8.1E-05 0.539245 1438375_at 14115 Fbln2 4 - down 344 SQ only Fibulin 2 0.351729 0.832027 0.00939 0.538565 mitochondrial ribosomal protein 1435966_x_at 68537 Mrpl13 4 - down 344 SQ only L13 0.206427 0.849841 0.00014 0.538245

glycerophosphodiest er phosphodiesterase 1424150_at 233552 Gdpd5 4 - down 344 SQ only domain containing 5 0.33821 1.102614 0.00047 0.538003 phosphate cytidylyltransferase 1, choline, beta 1437648_at 236899 Pcyt1b 4 - down 344 SQ only isoform 0.743021 0.958551 0.00509 0.537933 ring finger protein 1425124_at 76072 Rnf183 4 - down 344 SQ only 183 0.344275 0.837037 0.00117 0.537633 vacuolar protein 1453564_a_at 66700 Vps24 4 - down 344 SQ only sorting 24 (yeast) 0.654633 0.951368 0.00015 0.537458 pleckstrin homology domain containing, family H (with MyTH4 domain) 1452517_at 211945 Plekhh1 4 - down 344 SQ only member 1 0.980506 1.062106 0.00398 0.537352 FYVE, RhoGEF and PH domain 1433398_at 30938 Fgd3 4 - down 344 SQ only containing 3 0.121001 0.747793 0.00431 0.537352

single-stranded DNA 1452616_s_at 381760 Ssbp1 4 - down 344 SQ only binding protein 1 0.536846 0.932074 0.00027 0.536221 phospholipase C, 1431892_a_at 72469 Plcd3 4 - down 344 SQ only delta 3 0.642812 0.94569 0.00199 0.535895

TRAF2 and NCK interacting kinase /// similar to [Segment 1 of 2] Traf2 and NCK-interacting kinase /// region containing TRAF2 and NCK interacting kinase; RIKEN cDNA C630040K21 1455256_at 665113 // Tnik /// LOC6654 - down 344 SQ only gene 0.069364 0.771011 0.00022 0.535403 muscle, skeletal, receptor tyrosine 1450511_at 18198 Musk 4 - down 344 SQ only kinase 0.832983 1.048558 0.00581 0.53533

Rho guanine nucleotide exchange 1427386_at 230972 Arhgef16 4 - down 344 SQ only factor (GEF) 16 0.058939 0.76294 0.0004 0.535234 dual specificity 1418714_at 18218 Dusp8 4 - down 344 SQ only phosphatase 8 0.029711 0.768001 0.00114 0.534925 interleukin 23, alpha 1419529_at 83430 Il23a 4 - down 344 SQ only subunit p19 0.173658 1.148328 0.00045 0.53426 related RAS viral (r- ras) oncogene 1417398_at 66922 Rras2 4 - down 344 SQ only homolog 2 0.002966 0.75462 5E-05 0.533991 exostoses (multiple) 1417730_at 14042 Ext1 4 - down 344 SQ only 1 0.438073 0.91114 0.00033 0.533614 RIKEN cDNA 1453207_at 554362 2900053A13Ri 4 - down 344 SQ only 2900053A13 gene 0.24913 0.783671 0.00935 0.533492 RIKEN cDNA 1442770_at 268469 9530033F24Ri 4 - down 344 SQ only 9530033F24 gene 0.459111 1.089989 0.00269 0.532772 TYRO protein tyrosine kinase 1450792_at 22177 Tyrobp 4 - down 344 SQ only binding protein 0.098344 0.804045 0.00139 0.532765 1428435_at 17831 Muc2 4 - down 344 SQ only mucin 2 0.324001 0.831907 0.00531 0.532645 EGF-like repeats and discoidin I-like 1433474_at 13612 Edil3 4 - down 344 SQ only domains 3 0.793446 1.140496 0.00174 0.532479 1439221_s_at 21939 Cd40 4 - down 344 SQ only CD40 antigen 0.799371 1.092723 0.00198 0.532189 pleckstrin homology domain containing, family H (with MyTH4 domain) 1447807_s_at 211945 Plekhh1 4 - down 344 SQ only member 1 0.480455 0.908113 0.00035 0.532079 fer-1-like 4 (C. 1453794_at 74562 Fer1l4 4 - down 344 SQ only elegans) 0.010318 0.759958 0.00021 0.531438 RIKEN cDNA 1460697_s_at 66618 2610209M04R 4 - down 344 SQ only 2610209M04 gene 0.193861 0.804962 0.00386 0.531294 ATX1 (antioxidant protein 1) homolog 1 1415760_s_at 11927 Atox1 4 - down 344 SQ only (yeast) 0.318091 0.876444 0.00203 0.530628 minichromosome maintenance deficient 2 mitotin (S. 1448777_at 17216 Mcm2 4 - down 344 SQ only cerevisiae) 0.922349 1.001555 0.00186 0.530568

expressed sequence 1458510_at 270156 AU019823 4 - down 344 SQ only AU019823 0.675985 0.958389 0.00023 0.529987

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, 1420824_at 20354 Sema4d 4 - down 344 SQ only (semaphorin) 4D 0.577626 0.952019 0.00102 0.528734 RIKEN cDNA 1425684_at 67861 2310005E10Ri 4 - down 344 SQ only 2310005E10 gene 0.229742 0.864569 0.00506 0.524712

1444439_at 76809 Bri3bp 4 - down 344 SQ only Bri3 binding protein 0.612707 0.948822 0.00369 0.524284 SHQ1 homolog (S. 1428927_at 72171 Shq1 4 - down 344 SQ only cerevisiae) 0.75628 1.037466 0.00037 0.523559 ras homolog gene 1434794_at 23912 Rhof 4 - down 344 SQ only family, member f 0.335385 0.843026 0.00243 0.523411 1422783_a_at 16687 Krt6a 4 - down 344 SQ only keratin 6A 0.576999 0.899558 0.00318 0.522446

SMAD specific E3 ubiquitin protein ligase 1 /// similar to Smad ubiquitination regulatory factor 1 (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) 1428396_at 640390 // Smurf1 /// LOC4 - down 344 SQ only (hSMURF1) 0.014211 0.762629 0.00018 0.520046 cDNA sequence 1444546_at 212937 BC027057 4 - down 344 SQ only BC027057 0.309225 0.838497 0.0022 0.519609 1426560_a_at 114249 Npnt 4 - down 344 SQ only nephronectin 0.295549 0.863152 0.00018 0.5191

WD repeat domain, phosphoinositide 1428882_at 74781 Wipi2 4 - down 344 SQ only interacting 2 0.181215 0.8515 0.00323 0.518263

X-linked myotubular 1434278_at 17772 Mtm1 4 - down 344 SQ only myopathy gene 1 0.463807 1.262584 0.0053 0.518131 Glucocorticoid receptor DNA 1440675_at 232906 Grlf1 4 - down 344 SQ only binding factor 1 0.086867 0.730871 0.00708 0.518098 TBC1 domain family, 1419446_at 57915 Tbc1d1 4 - down 344 SQ only member 1 0.090683 0.79609 0.00124 0.517664 crumbs homolog 3 1455115_a_at 224912 Crb3 4 - down 344 SQ only (Drosophila) 0.846368 0.956869 0.00339 0.517637 PTC7 protein phosphatase homolog (S. 1455958_s_at 320717 Pptc7 4 - down 344 SQ only cerevisiae) 0.28072 0.891019 7.2E-06 0.517563 1460218_at 23833 Cd52 4 - down 344 SQ only CD52 antigen 0.116603 0.764444 0.00652 0.516764 RIKEN cDNA 1446204_at 212114 8030451K01Ri 4 - down 344 SQ only 8030451K01 gene 0.072608 0.76519 0.00242 0.516511 arrestin domain 1424759_at 66412 Arrdc4 4 - down 344 SQ only containing 4 0.141659 1.222851 1.6E-05 0.515957 cDNA sequence 1427041_at 230787 BC013712 4 - down 344 SQ only BC013712 0.513337 0.907818 0.00405 0.515573 similar to RP58 1456846_at 382639 LOC382639 4 - down 344 SQ only protein 0.573246 0.922232 0.00166 0.515046 Sterile alpha motif domain containing 1440589_at 320679 Samd12 4 - down 344 SQ only 12 0.442309 0.879023 0.00027 0.514321 1417240_at 22793 Zyx 4 - down 344 SQ only zyxin 0.069353 0.80806 0.00029 0.51165 uracil DNA 1425753_a_at 22256 Ung 4 - down 344 SQ only glycosylase 0.133769 0.794838 0.00431 0.511525

guanine nucleotide binding protein (G protein), gamma transducing activity 1428733_at 14710 Gngt2 4 - down 344 SQ only polypeptide 2 0.508952 0.907407 0.00609 0.510984 RIKEN cDNA 1450943_at 66441 2010012C16Ri4 - down 344 SQ only 2010012C16 gene 0.463473 0.898541 0.00171 0.509565 mitochondrial ribosomal protein 1449194_at 64658 Mrps25 4 - down 344 SQ only S25 0.833269 0.979998 0.00042 0.509422 1437360_at 279653 Pcdh19 4 - down 344 SQ only protocadherin 19 0.298224 0.802762 0.00762 0.508779

processing of precursor 5, ribonuclease P/MRP 1417972_s_at 117109 Pop5 4 - down 344 SQ only family (S. cerevisiae) 0.409987 0.856282 0.00591 0.508289

MARVEL (membrane- associating) domain 1426914_at 218518 Marveld2 4 - down 344 SQ only containing 2 0.206204 0.788912 0.00089 0.506679 heterogeneous nuclear ribonucleoprotein D- 1428225_s_at 50926 Hnrpdl 4 - down 344 SQ only like 0.461751 0.909618 0.0002 0.505461

DCN1, defective in cullin neddylation 1, domain containing 4 1455079_at 100737 Dcun1d4 4 - down 344 SQ only (S. cerevisiae) 0.388745 0.915227 0.00326 0.504438 replication factor C 1423700_at 69263 Rfc3 4 - down 344 SQ only (activator 1) 3 0.332008 0.895732 0.00131 0.503691 HIV-1 Rev binding 1425362_at 231801 Hrbl 4 - down 344 SQ only protein-like 0.120026 0.744882 0.00047 0.502862 RIKEN cDNA 1424087_at 66506 1810042K04Ri 4 - down 344 SQ only 1810042K04 gene 0.938079 0.971924 0.00619 0.501563

glucosaminyl (N- acetyl) transferase 1, 1460431_at 14537 Gcnt1 4 - down 344 SQ only core 2 0.6768 1.052583 0.00562 0.4999

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1450716_at 11504 Adamts1 4 - down 344 SQ only 1 motif, 1 0.081018 0.708914 0.00277 0.498286 chemokine (C-X-C 1418718_at 66102 Cxcl16 4 - down 344 SQ only motif) ligand 16 0.460471 1.169031 0.00242 0.498115 RIKEN cDNA 1429040_at 381598 2610005L07Ri 4 - down 344 SQ only 2610005L07 gene 0.754907 1.12441 0.00331 0.495836

phosphodiesterase 6A, cGMP-specific, 1450415_at 225600 Pde6a 4 - down 344 SQ only rod, alpha 0.00357 0.75658 0.00046 0.495034 replication protein 1448938_at 68240 Rpa3 4 - down 344 SQ only A3 0.068404 0.740482 0.00108 0.493532

catenin (cadherin associated protein), 1420930_s_at 54366 Ctnnal1 4 - down 344 SQ only alpha-like 1 0.210129 0.801611 0.00843 0.49346 cholinergic receptor, nicotinic, beta polypeptide 1 1420682_at 11443 Chrnb1 4 - down 344 SQ only (muscle) 0.328582 0.889299 0.00611 0.492228

transmembrane and 1434253_s_at 319880 Tmcc3 4 - down 344 SQ only coiled coil domains 3 0.27308 1.182826 0.00615 0.491786

Notch gene homolog 1421964_at 18131 Notch3 4 - down 344 SQ only 3 (Drosophila) 0.082433 0.729974 0.00427 0.491569

histone cell cycle regulation defective 1418229_s_at 56748 Hirip5 4 - down 344 SQ only interacting protein 5 0.249646 0.8785 7.7E-05 0.490737

Mammary gland RCB-0527 Jyg- MC(B) cDNA, RIKEN full-length enriched library, clone:G930041P03 product:unclassifiabl e, full insert 1439888_at ------4 - down 344 SQ only sequence 0.475036 0.915982 0.00221 0.489303 nuclear autoantigenic sperm protein (histone- 1416043_at 50927 Nasp 4 - down 344 SQ only binding) 0.605029 0.925732 0.00459 0.489043 RIKEN cDNA 1429189_at 71784 1110007C02Ri4 - down 344 SQ only 1110007C02 gene 0.116051 1.183543 0.00576 0.488555 mitochondrial ribosomal protein 1451178_at 68499 Mrpl53 4 - down 344 SQ only L53 0.217152 0.855127 0.00056 0.486648 UDP- Gal:betaGlcNAc beta 1,4- galactosyltransferas 1449435_at 57370 B4galt3 4 - down 344 SQ only e, polypeptide 3 0.917742 0.993187 0.00451 0.486102 frizzled homolog 6 1417301_at 14368 Fzd6 4 - down 344 SQ only (Drosophila) 0.558436 0.939518 0.00789 0.486033 1415818_at 11749 Anxa6 4 - down 344 SQ only annexin A6 0.783246 1.040747 0.00486 0.485941 RIKEN cDNA 1416628_at 66836 0610006I08Rik4 - down 344 SQ only 0610006I08 gene 0.691194 1.037988 0.00886 0.485715 ubiquitin specific 1451514_at 216835 Usp43 4 - down 344 SQ only peptidase 43 0.515983 0.848918 0.00861 0.48533 RIKEN cDNA 1429055_at 71653 4930506M07R 4 - down 344 SQ only 4930506M07 gene 0.469183 1.153777 2.8E-05 0.48517 serine peptidase inhibitor, Kazal type 1454710_at 69982 Spink2 4 - down 344 SQ only 2 0.241001 0.80248 0.00016 0.484059 RIKEN cDNA 1452215_at 75758 9130401M01R 4 - down 344 SQ only 9130401M01 gene 0.062645 0.866011 6.2E-06 0.483352 interleukin 13 1427164_at 16164 Il13ra1 4 - down 344 SQ only receptor, alpha 1 0.904902 0.987828 0.00302 0.483124 RIKEN cDNA 1430159_at 74744 5830408C22Ri4 - down 344 SQ only 5830408C22 gene 0.50763 0.867173 0.00926 0.482736 DNA segment, Chr 5, ERATO Doi 579, 1439691_at 320661 D5Ertd579e 4 - down 344 SQ only expressed 0.070879 0.710662 0.00661 0.482022 TAR (HIV) RNA 1438952_x_at 21357 Tarbp2 4 - down 344 SQ only binding protein 2 0.359949 0.825687 0.00662 0.481972 RIKEN cDNA 1436283_at 330428 D630042F21R 4 - down 344 SQ only D630042F21 gene 0.374897 0.827129 0.00898 0.481328 mutS homolog 2 (E. 1447888_x_at 17685 Msh2 4 - down 344 SQ only coli) 0.345609 0.786032 0.00787 0.480281

RIKEN cDNA 4631422O05 gene /// similar to downregulated in ovarian cancer 1 isoform 2 /// similar to downregulated in ovarian cancer 1 1428861_at 667770 // 4631422O05R 4 - down 344 SQ only isoform 2 0.06608 0.753492 0.00361 0.479758 1419128_at 16411 Itgax 4 - down 344 SQ only integrin alpha X 0.547042 0.928517 0.00704 0.479288 RIKEN cDNA 1435755_at 68554 1110001A16Ri 4 - down 344 SQ only 1110001A16 gene 0.64185 0.936976 0.00059 0.478313 1417790_at 13448 Dok1 4 - down 344 SQ only docking protein 1 0.899103 0.993869 6.7E-06 0.478023 Pentatricopeptide 1428090_at 69956 Ptcd3 4 - down 344 SQ only repeat domain 3 0.351102 0.894951 0.00028 0.476593 3-oxoacid CoA 1436750_a_at 67041 Oxct1 4 - down 344 SQ only transferase 1 0.752469 0.98823 0.00906 0.476568 Adult male cecum cDNA, RIKEN full- length enriched library, clone:9130204C03 product:unclassifiabl e, full insert 1435265_at ------4 - down 344 SQ only sequence 0.764829 0.984711 0.00015 0.475742 1420183_at 16939 Lor 4 - down 344 SQ only Loricrin 0.83558 1.180845 0.00085 0.474874 1428785_at 75723 Amotl1 4 - down 344 SQ only angiomotin-like 1 0.183796 0.771407 0.00252 0.474698

Gardner-Rasheed feline sarcoma viral (Fgr) oncogene 1419526_at 14191 Fgr 4 - down 344 SQ only homolog 0.38234 0.82898 0.00954 0.474634

expressed sequence 1452359_at 100532 AA536743 4 - down 344 SQ only AA536743 0.066201 0.73227 6.4E-05 0.473536

Ubiquinol- cytochrome c reductase, complex 1437134_at 22272 Uqcrq 4 - down 344 SQ only III subunit VII 0.454664 0.839116 0.00679 0.472709 Prkr interacting protein 1 (IL11 1417425_at 66801 Prkrip1 4 - down 344 SQ only inducible) 0.416135 0.856944 0.00225 0.472137 cell division cycle 45 homolog (S. 1416575_at 12544 Cdc45l 4 - down 344 SQ only cerevisiae)-like 0.922954 1.103511 0.00449 0.470181 peptidylprolyl isomerase F 1438955_x_at 105675 Ppif 4 - down 344 SQ only (cyclophilin F) 0.113039 0.844522 0.00344 0.46881 leucine-rich repeat LGI family, member 1434121_at 243914 Lgi4 4 - down 344 SQ only 4 0.826303 1.035237 0.00102 0.468748 cyclin-dependent 1460472_at 69681 Cdk3 4 - down 344 SQ only kinase 3 0.444398 0.903693 0.00013 0.467963 regulator of G- 1416286_at 19736 Rgs4 4 - down 344 SQ only protein signaling 4 0.431207 0.831261 0.00722 0.466928 SH3-domain binding 1448328_at 24055 Sh3bp2 4 - down 344 SQ only protein 2 0.256439 0.847373 0.00016 0.466208 YEATS domain 1459108_a_at 208146 Yeats2 4 - down 344 SQ only containing 2 0.112949 0.781232 1.6E-05 0.466204 3-oxoacid CoA 1428140_at 67041 Oxct1 4 - down 344 SQ only transferase 1 0.390843 1.071722 0.0011 0.466

cyclin-dependent kinase-like 2 (CDC2- 1449229_a_at 53886 Cdkl2 4 - down 344 SQ only related kinase) 0.348522 1.16438 0.00044 0.465741 brix domain 1444666_at 67239 Bxdc1 4 - down 344 SQ only containing 1 0.547752 1.105984 0.00869 0.465428 RIKEN cDNA 1423786_at 232210 8430410A17Ri 4 - down 344 SQ only 8430410A17 gene 0.415897 0.925076 0.00019 0.465129 LSM3 homolog, U6 small nuclear RNA associated (S. 1448536_at 67678 Lsm3 4 - down 344 SQ only cerevisiae) 0.040453 0.754589 0.00049 0.461848 histone cell cycle regulation defective 1418228_at 56748 Hirip5 4 - down 344 SQ only interacting protein 5 0.168227 0.893258 1E-05 0.45806

SMAD specific E3 ubiquitin protein ligase 1 /// similar to Smad ubiquitination regulatory factor 1 (Ubiquitin--protein ligase SMURF1) (Smad-specific E3 ubiquitin ligase 1) 1428395_at 640390 // Smurf1 /// LOC4 - down 344 SQ only (hSMURF1) 0.05836 0.759746 0.00067 0.457724 SLIT-ROBO Rho GTPase activating 1424588_at 259302 Srgap3 4 - down 344 SQ only protein 3 0.435421 0.878708 0.00058 0.457077

platelet derived 1418711_at 18590 Pdgfa 4 - down 344 SQ only growth factor, alpha 0.198988 0.848902 0.00066 0.456994 G protein-coupled 1440225_at 224792 Gpr116 4 - down 344 SQ only receptor 116 0.302389 0.824507 0.00242 0.456185

Rap guanine nucleotide exchange 1437946_x_at 223864 Rapgef3 4 - down 344 SQ only factor (GEF) 3 0.0733 0.701989 0.00103 0.454368 adaptor-related protein complex AP- 1455735_at 252903 Ap1s3 4 - down 344 SQ only 1, sigma 3 0.330542 1.23103 0.00153 0.454333

abhydrolase domain 1428428_at 68758 Abhd11 4 - down 344 SQ only containing 11 0.034894 0.845586 6.2E-05 0.453298

proline-serine- threonine phosphatase- 1421410_a_at 19201 Pstpip2 4 - down 344 SQ only interacting protein 2 0.304328 0.785384 0.00094 0.453089 Zinc finger, DHHC domain containing 1460048_at 243983 Zdhhc13 4 - down 344 SQ only 13 0.563343 0.912939 0.00151 0.452136

pleckstrin and Sec7 1455068_at 215632 Psd4 4 - down 344 SQ only domain containing 4 0.984936 0.988383 0.00632 0.452098

radical S-adenosyl methionine domain 1440875_a_at 237926 Rsad1 4 - down 344 SQ only containing 1 0.471869 0.915533 0.0018 0.45097

1427357_at 72269 Cda 4 - down 344 SQ only cytidine deaminase 0.000657 0.791144 3.2E-06 0.450597

protocadherin 9 /// similar to protocadherin 9 1458269_at 211712 // Pcdh9 /// LOC64 - down 344 SQ only isoform 1 precursor 0.000664 0.672026 0.00195 0.450003 transmembrane and tetratricopeptide 1429809_at 278279 Tmtc2 4 - down 344 SQ only repeat containing 2 0.419726 1.25349 0.00018 0.449042

peroxisome 1451393_at 74043 Pex26 4 - down 344 SQ only biogenesis factor 26 0.089505 0.857504 1.9E-06 0.448031

Rap guanine nucleotide exchange 1424471_at 223864 Rapgef3 4 - down 344 SQ only factor (GEF) 3 0.265059 0.807202 0.002 0.447733 LEM domain 1445642_at 213409 Lemd1 4 - down 344 SQ only containing 1 0.927374 1.037442 0.00063 0.447158

1418708_at 11425 Apoc4 4 - down 344 SQ only apolipoprotein C-IV 0.458669 0.842703 0.00608 0.447044

CCR4 carbon catabolite repression 1425837_a_at 12457 Ccrn4l 4 - down 344 SQ only 4-like (S. cerevisiae) 0.886352 0.96113 0.0012 0.446226 lysophosphatidylglyc erol acyltransferase 1424349_a_at 226856 Lpgat1 4 - down 344 SQ only 1 0.165328 0.776128 2E-05 0.445829 phospholipase C-like 1436335_at 269615 Plcl4 4 - down 344 SQ only 4 0.505904 1.070594 0.00988 0.444171 1431146_a_at 66871 Cpne8 4 - down 344 SQ only copine VIII 0.134053 0.724056 0.00021 0.443608

upstream binding transcription factor, 1455490_at 21429 Ubtf 4 - down 344 SQ only RNA polymerase I 0.713276 0.943305 0.00138 0.442665

UDP-N-acetyl-alpha- D-galactosamine: polypeptide N- acetylgalactosaminyl 1452232_at 108150 Galnt7 4 - down 344 SQ only transferase 7 0.366922 1.10735 0.00062 0.442411 Uridine-cytidine 1441858_at 80914 Uck2 4 - down 344 SQ only kinase 2 0.004775 0.736167 0.00178 0.442351

1455291_s_at 387524 Znrf2 4 - down 344 SQ only zinc and ring finger 2 0.422356 0.874798 0.00308 0.441338 RIKEN cDNA 1453434_at 76311 1110019D14Ri4 - down 344 SQ only 1110019D14 gene 0.728955 0.965516 0.00123 0.44077 1448612_at 55948 Sfn 4 - down 344 SQ only stratifin 0.839245 1.038705 0.00086 0.440437 RIKEN cDNA 1433645_at 70174 2210409B22Ri 4 - down 344 SQ only 2210409B22 gene 0.144858 0.800588 0.00021 0.440416 enabled homolog 1424801_at 13800 Enah 4 - down 344 SQ only (Drosophila) 0.256056 1.184451 0.00037 0.440226 alkB, alkylation repair homolog 2 (E. 1455673_at 231642 Alkbh2 4 - down 344 SQ only coli) 0.001506 0.84569 0.00019 0.439589 G protein-coupled 1418379_s_at 78560 Gpr124 4 - down 344 SQ only receptor 124 0.508221 0.91443 6.3E-05 0.439169

pleckstrin homology domain containing, 1418108_at 170799 Plekhk1 4 - down 344 SQ only family K member 1 0.870144 1.012547 0.00898 0.43911 1452251_at 26422 Nbea 4 - down 344 SQ only neurobeachin 0.294435 0.880144 0.00033 0.438866 1421359_at 19713 Ret 4 - down 344 SQ only ret proto-oncogene 0.955434 0.995167 0.00026 0.438862 1455618_x_at 232670 Tspan33 4 - down 344 SQ only tetraspanin 33 0.299621 0.851447 0.00122 0.436559

regulator of G- 1453129_a_at 71729 Rgs12 4 - down 344 SQ only protein signaling 12 0.198177 0.710683 0.00617 0.436117 1416333_at 13449 Dok2 4 - down 344 SQ only docking protein 2 0.630272 1.059648 0.00019 0.4361 hypothetical 1439295_x_at 434179 LOC434179 4 - down 344 SQ only LOC434179 0.183374 0.835545 0.0011 0.435976

killer cell lectin-like receptor, subfamily 1425888_at 170733 Klra17 4 - down 344 SQ only A, member 17 0.296114 0.767153 0.00262 0.434153 lunatic fringe gene homolog 1420643_at 16848 Lfng 4 - down 344 SQ only (Drosophila) 0.021865 0.765714 1.4E-07 0.432961 protein tyrosine phosphatase, non- 1460188_at 15170 Ptpn6 4 - down 344 SQ only receptor type 6 0.461849 0.871604 0.00994 0.43271

phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 1456482_at 18710 Pik3r3 4 - down 344 SQ only 3 (p55) 0.483381 1.073299 0.00049 0.432663

expressed sequence 1452599_s_at 106672 AI413582 4 - down 344 SQ only AI413582 0.367977 0.890448 0.0003 0.431244 RIKEN cDNA 1432464_a_at 69697 2310057J16Rik4 - down 344 SQ only 2310057J16 gene 0.7929 0.993387 0.00035 0.430883 adenosine 1417976_at 11486 Ada 4 - down 344 SQ only deaminase 0.83203 1.093945 0.00733 0.430447 transmembrane 1434726_at 106757 Tmem146 4 - down 344 SQ only protein 146 0.026742 0.799067 0.00134 0.429307 1427747_a_at 16819 Lcn2 4 - down 344 SQ only lipocalin 2 0.845148 1.099745 0.0049 0.427796 lysophosphatidylglyc erol acyltransferase 1424350_s_at 226856 Lpgat1 4 - down 344 SQ only 1 0.337102 0.805983 0.00096 0.426444

Rap guanine nucleotide exchange 1424470_a_at 223864 Rapgef3 4 - down 344 SQ only factor (GEF) 3 0.05753 0.772099 0.00095 0.425119 1424268_at 228608 Smox 4 - down 344 SQ only spermine oxidase 0.464776 0.863626 0.00325 0.424755 ovo-like 2 1449205_at 107586 Ovol2 4 - down 344 SQ only (Drosophila) 0.489677 0.931484 0.00027 0.423681

lymphocyte antigen 1417185_at 110454 Ly6a 4 - down 344 SQ only 6 complex, locus A 0.182999 0.829095 0.00378 0.422589 RIKEN cDNA 1453087_at 70744 6330403L08Ri 4 - down 344 SQ only 6330403L08 gene 0.205649 0.701467 0.00408 0.421844 RIKEN cDNA 1447822_x_at 70240 2700038N03Ri4 - down 344 SQ only 2700038N03 gene 0.153364 0.811664 0.00048 0.421796 1450309_at 56079 Astn2 4 - down 344 SQ only astrotactin 2 0.658979 1.084008 0.00114 0.421548 1455247_at 75723 Amotl1 4 - down 344 SQ only angiomotin-like 1 0.309457 0.802041 0.00328 0.420484 lactate 1434499_a_at 16832 Ldhb 4 - down 344 SQ only dehydrogenase B 0.790033 0.973665 0.00526 0.420457 1452107_s_at 114249 Npnt 4 - down 344 SQ only Nephronectin 0.141746 0.838113 0.00039 0.420065 nuclear receptor 1422737_at 17979 Ncoa3 4 - down 344 SQ only coactivator 3 0.180236 0.788817 0.0015 0.419174

pleckstrin homology, Sec7 and coiled/coil 1460437_at 72318 Pscd4 4 - down 344 SQ only domains 4 0.888152 0.961362 0.0088 0.419075 glia maturation 1419194_s_at 63986 Gmfg 4 - down 344 SQ only factor, gamma 0.203426 0.823355 0.00096 0.418119 leucine rich repeat 1453628_s_at 74249 Lrrc2 4 - down 344 SQ only containing 2 0.604433 1.177295 0.00172 0.418089 RIKEN cDNA 1446088_at 320242 9430081I23Rik4 - down 344 SQ only 9430081I23 gene 0.049337 0.671453 0.00084 0.414603 RIKEN cDNA 1456210_at 227545 5430407P10Ri 4 - down 344 SQ only 5430407P10 gene 0.111582 0.687183 0.00091 0.412079 tetratricopeptide repeat, ankyrin repeat and coiled- 1435078_at 77097 Tanc2 4 - down 344 SQ only coil containing 2 0.508776 0.942999 0.00342 0.41136 RIKEN cDNA 1435641_at 320137 9530018I07Rik4 - down 344 SQ only 9530018I07 gene 0.31866 1.426808 0.00027 0.411172 RIKEN cDNA 1457566_at 210503 A830058L05Ri 4 - down 344 SQ only A830058L05 gene 0.611259 1.065059 1.7E-05 0.41097

serine (or cysteine) peptidase inhibitor, clade A, member 4, 1444296_a_at 321018 Serpina4-ps1 4 - down 344 SQ only pseudogene 1 0.486141 0.899494 0.00524 0.410961 1436895_at 212285 Centd1 4 - down 344 SQ only centaurin, delta 1 0.306575 0.792521 0.00048 0.409852

CDK5 regulatory subunit associated 1448626_at 66971 Cdk5rap1 4 - down 344 SQ only protein 1 0.209042 1.2327 0.00039 0.409708

allograft 1418204_s_at 11629 Aif1 4 - down 344 SQ only inflammatory factor 1 0.259985 0.853046 0.00055 0.408912

general transcription factor IIIC, 1423998_at 70239 Gtf3c5 4 - down 344 SQ only polypeptide 5 0.291332 0.792576 0.00228 0.408367 FK506 binding 1458729_at 14228 Fkbp4 4 - down 344 SQ only protein 4 0.2943 0.798129 0.00119 0.408228

MARVEL (membrane- associating) domain 1451764_at 73608 Marveld3 4 - down 344 SQ only containing 3 0.084764 1.274692 2.2E-05 0.407644 1449399_a_at 16176 Il1b 4 - down 344 SQ only interleukin 1 beta 0.03695 0.639215 0.00517 0.407108

solute carrier family 40 (iron-regulated transporter), member 1417061_at 53945 Slc40a1 4 - down 344 SQ only 1 0.106751 0.743044 0.00012 0.406193

expressed sequence 1448067_at 105332 AW011956 4 - down 344 SQ only AW011956 0.621992 0.862861 0.00946 0.406129 expressed sequence 1452273_at 105732 AA409316 4 - down 344 SQ only AA409316 0.10539 0.810645 5.7E-05 0.405687 1422917_at 13835 Epha1 4 - down 344 SQ only Eph receptor A1 0.566101 0.944091 1.3E-05 0.405235 zinc finger, DHHC domain containing 1428307_at 243983 Zdhhc13 4 - down 344 SQ only 13 0.854567 1.008634 0.00051 0.404972 RAD18 homolog (S. 1435826_at 58186 Rad18 4 - down 344 SQ only cerevisiae) 0.001673 0.651502 6.5E-05 0.404727

1417522_at 67731 Fbxo32 4 - down 344 SQ only F-box only protein 32 0.526297 0.827807 0.00916 0.403087 crumbs homolog 3 1434851_s_at 224912 Crb3 4 - down 344 SQ only (Drosophila) 0.399408 0.87061 0.00011 0.402695 eosinophil- associated, ribonuclease A 1449846_at 13587 Ear2 4 - down 344 SQ only family, member 2 0.052441 0.658386 0.00011 0.402625

FGF receptor 1424616_s_at 233575 Frag1 4 - down 344 SQ only activating protein 1 0.417754 0.849485 0.00427 0.40251 1452106_at 114249 Npnt 4 - down 344 SQ only nephronectin 0.120907 0.879963 9.3E-05 0.401071 eyes absent 2 homolog 1424127_at 14049 Eya2 4 - down 344 SQ only (Drosophila) 0.169668 1.341732 0.00098 0.39975

sortilin-related receptor, LDLR class 1426258_at 20660 Sorl1 4 - down 344 SQ only A repeats-containing 0.243825 0.822007 0.00063 0.399523 1453313_at 75747 Sesn3 4 - down 344 SQ only sestrin 3 0.163998 0.684626 0.00616 0.399128 neuralized-like homolog 1456854_at 18011 Neurl 4 - down 344 SQ only (Drosophila) 0.103787 0.650031 0.0059 0.396457 RIKEN cDNA 1457705_at 78279 5330421C15Ri4 - down 344 SQ only 5330421C15 gene 0.686708 1.127948 0.00018 0.395872 dual specificity 1448985_at 105352 Dusp22 4 - down 344 SQ only phosphatase 22 0.179754 0.781772 0.00204 0.395802

SH3 domain binding glutamic acid-rich 1434109_at 212531 Sh3bgrl2 4 - down 344 SQ only protein like 2 0.677598 1.09055 0.00447 0.39561 grainyhead-like 2 1431878_at 252973 Grhl2 4 - down 344 SQ only (Drosophila) 0.18944 0.778867 0.00989 0.394812 argininosuccinate 1416239_at 11898 Ass1 4 - down 344 SQ only synthetase 1 0.275917 1.315465 0.00123 0.391362 RIKEN cDNA 1428860_at 223626 4930572J05Rik4 - down 344 SQ only 4930572J05 gene 0.800193 1.067982 0.00272 0.391094 glia maturation 1419193_a_at 63986 Gmfg 4 - down 344 SQ only factor, gamma 0.915186 0.946397 0.00424 0.390665 cDNA sequence 1436591_at 231668 BC023744 4 - down 344 SQ only BC023744 0.137446 0.846465 5.4E-06 0.390193 histocompatibility 2, blastocyst /// RIKEN cDNA 2410017I17 gene /// similar to MHC class I antigen precursor /// MHC class I like protein GS17 /// similar to histocompatibility 2, blastocyst /// similar to RT1 class Ia, locus A1 /// similar to RT1 class Ia, locus A1 /// hypothetical 1447260_at 14963 /// H2-Bl /// 241004 - down 344 SQ only protein LOC677505 0.250144 0.721498 0.00366 0.390137 somatostatin 1422281_at 20608 Sstr4 4 - down 344 SQ only receptor 4 0.486947 1.361044 0.00615 0.38835 chemokine (C-X-C 1449195_s_at 66102 Cxcl16 4 - down 344 SQ only motif) ligand 16 0.857388 1.078071 0.00063 0.388309 protein interacting 1419384_at 18693 Pick1 4 - down 344 SQ only with C kinase 1 0.26032 0.843636 2.7E-05 0.388179

expressed sequence 1427175_at 233066 AI428936 4 - down 344 SQ only AI428936 0.937745 1.02875 0.00627 0.387775 1418671_at 12337 Capn5 4 - down 344 SQ only calpain 5 0.091705 0.703407 0.00264 0.387525 CDC42 effector protein (Rho 1422642_at 260409 Cdc42ep3 4 - down 344 SQ only GTPase binding) 3 0.187963 0.768149 0.00205 0.386921

interferon activated 1457666_s_at 26388 Ifi202b 4 - down 344 SQ only gene 202B 0.581523 1.119362 0.00092 0.386712

connector enhancer of kinase suppressor of Ras 1 /// similar to connector enhancer of kinase suppressor 1455399_at 194231 // Cnksr1 /// LOC 4 - down 344 SQ only of Ras 1 0.975545 1.036881 0.00011 0.384832 CDNA sequence 1443624_at 245945 BC013481 4 - down 344 SQ only BC013481 0.121716 0.671106 0.00245 0.384751 1435714_x_at 239114 Il17d 4 - down 344 SQ only interleukin 17D 0.463683 0.871933 0.00123 0.384201

interferon activated 1421551_s_at 26388 Ifi202b 4 - down 344 SQ only gene 202B 0.21704 1.255123 0.00375 0.383853 RIKEN cDNA 1431227_at 69641 2310040A13Ri 4 - down 344 SQ only 2310040A13 gene 0.221157 0.732919 0.00959 0.383617 plexin domain 1418912_at 67448 Plxdc2 4 - down 344 SQ only containing 2 0.075722 0.695819 0.00261 0.381136 fatty acid binding protein 5, epidermal /// similar to Fatty acid-binding protein, epidermal (E-FABP) (Psoriasis- associated fatty acid- binding protein homolog) (PA-FABP) (Keratinocyte lipid- binding protein) /// similar to Fatty acid- binding protein, epidermal (E-FABP) (Psoriasis- associated fatty acid- binding protein homolog) (PA-FABP) (Keratinocyte lipid- binding protein) /// similar to Fatty acid- binding protein, epidermal (E-FABP) (Psoriasis- associated fatty acid- binding protein homolog) (PA-FABP) (Keratinocyte lipid- binding protein) /// similar to Fatty acid- binding protein, epidermal (E-FABP) (Psoriasis- associated fatty acid- binding protein homolog) (PA-FABP) (Keratinocyte lipid- 1416021_a_at 16592 /// Fabp5 /// LOC64 - down 344 SQ only binding protein) 0.201526 1.106936 0.00151 0.380805 1444735_at ------4 - down 344 SQ only --- 0.00526 0.684459 1.5E-05 0.379658 leucine zipper transcription 1450734_at 89867 Lztr2 4 - down 344 SQ only regulator 2 0.744644 0.899448 0.00996 0.379318 transmembrane 1417895_a_at 66260 Tmem54 4 - down 344 SQ only protein 54 0.98059 1.041316 0.00027 0.37862

UDP-N-acetyl-alpha- D-galactosamine: polypeptide N- acetylgalactosaminyl 1426908_at 108150 Galnt7 4 - down 344 SQ only transferase 7 0.198986 1.188532 0.0011 0.378105 RIKEN cDNA 1444183_at 77417 C030013C21R 4 - down 344 SQ only C030013C21 gene 0.255838 0.715305 0.00982 0.377183 DENN/MADD domain containing 1451363_a_at 72121 Dennd2d 4 - down 344 SQ only 2D 0.703201 0.9587 0.00045 0.376461 tubulin tyrosine ligase-like family, 1431309_at 330010 Ttll10 4 - down 344 SQ only member 10 0.092307 0.65994 0.00019 0.376382 RIKEN cDNA 1447870_x_at 67816 1110002E22Ri 4 - down 344 SQ only 1110002E22 gene 0.493634 1.257475 0.00983 0.376135 1452269_at 20743 Spnb3 4 - down 344 SQ only spectrin beta 3 0.785635 0.956763 0.00018 0.374797

expressed sequence 1425163_at 224833 AI661453 4 - down 344 SQ only AI661453 0.024866 0.687675 2.3E-05 0.374473

Solute carrier family 1446318_at 100434 Slc44a1 4 - down 344 SQ only 44, member 1 0.328135 0.775253 0.00202 0.37324 FYVE, RhoGEF and PH domain 1419515_at 26382 Fgd2 4 - down 344 SQ only containing 2 0.016099 0.704964 0.00629 0.370661

surfactant 1420378_at 20390 Sftpd 4 - down 344 SQ only associated protein D 0.234522 0.733461 0.00064 0.369844 1438552_x_at 22793 Zyx 4 - down 344 SQ only zyxin 0.080798 0.708167 0.0037 0.369773 p21 (CDKN1A)- 1455200_at 214230 Pak6 4 - down 344 SQ only activated kinase 6 0.129314 0.723101 0.00051 0.369635

nitric oxide synthase 2, inducible, 1420393_at 18126 Nos2 4 - down 344 SQ only macrophage 0.295634 0.71289 0.00672 0.369109 Dynamin binding 1459196_at 71972 Dnmbp 4 - down 344 SQ only protein 0.252166 0.823208 0.00476 0.36594

solute carrier family 25 (mitochondrial carrier, phosphate 1428929_s_at 67582 Slc25a26 4 - down 344 SQ only carrier), member 26 0.152401 0.717313 0.00323 0.365757 plasminogen 1415806_at 18791 Plat 4 - down 344 SQ only activator, tissue 0.081774 0.637644 0.00123 0.364052 poliovirus receptor- 1451690_a_at 71740 Pvrl4 4 - down 344 SQ only related 4 0.915976 0.958772 0.00778 0.363742 1426561_a_at 114249 Npnt 4 - down 344 SQ only nephronectin 0.756399 0.97795 1.1E-05 0.363134 chemokine (C-X-C 1457644_s_at 14825 Cxcl1 4 - down 344 SQ only motif) ligand 1 0.045735 0.603266 0.00722 0.362246

lymphocyte antigen 1421571_a_at 17067 Ly6c 4 - down 344 SQ only 6 complex, locus C 0.113025 0.705045 0.00011 0.360251 RIKEN cDNA 1447155_at 77996 D730039F16R 4 - down 344 SQ only D730039F16 gene 0.681484 0.90604 0.0054 0.359826

1420679_a_at 66253 Aig1 4 - down 344 SQ only androgen-induced 1 0.450557 1.179307 0.00163 0.359664 transmembrane 1441917_s_at 94346 Tmem40 4 - down 344 SQ only protein 40 0.435022 1.148189 6.1E-05 0.358902 gene model 967, 1435283_s_at 381217 Gm967 4 - down 344 SQ only (NCBI) 0.474436 0.854824 0.00395 0.358877 serine protease inhibitor, Kunitz type 1416627_at 20732 Spint1 4 - down 344 SQ only 1 0.520651 0.937666 0.00118 0.358818 interferon-stimulated 1419569_a_at 57444 Isg20 4 - down 344 SQ only protein 0.136133 0.794827 0.00105 0.357931 tight junction protein 1417896_at 27375 Tjp3 4 - down 344 SQ only 3 0.806873 1.065378 5.2E-07 0.357834 1428983_at 20289 Scx 4 - down 344 SQ only scleraxis 0.299701 0.835158 0.00038 0.357305 serologically defined colon cancer antigen 1456538_at 76816 Sdccag8 4 - down 344 SQ only 8 0.627921 1.181343 0.00327 0.357065 RIKEN cDNA 1430051_at 214639 4930486L24Ri 4 - down 344 SQ only 4930486L24 gene 0.653809 1.177538 1.3E-05 0.354007 UDP-N-acetyl-alpha- D- galactosamine:polyp eptide N- acetylgalactosaminyl 1417588_at 14425 Galnt3 4 - down 344 SQ only transferase 3 0.119109 0.828037 0.00011 0.353597 Sh3 domain YSC- 1449579_at 24057 Sh3yl1 4 - down 344 SQ only like 1 0.133461 1.363406 3.7E-05 0.352464 acyl-Coenzyme A oxidase 2, branched 1420673_a_at 93732 Acox2 4 - down 344 SQ only chain 0.52327 0.880485 0.0003 0.351603 enabled homolog 1424800_at 13800 Enah 4 - down 344 SQ only (Drosophila) 0.510228 0.946023 0.00042 0.350458 DNA segment, Chr 6, Miriam Meisler 5, 1449358_at 110958 D6Mm5e 4 - down 344 SQ only expressed 0.054853 0.589654 0.00202 0.349542 1434017_at ------4 - down 344 SQ only --- 0.084128 0.799586 0.00033 0.348459 muscleblind-like 3 1422836_at 171170 Mbnl3 4 - down 344 SQ only (Drosophila) 0.967571 1.009917 0.00113 0.348341 phosphoglucomutas 1451149_at 72157 Pgm2 4 - down 344 SQ only e 2 0.039409 0.703498 0.00165 0.348021 epithelial V-like 1448265_x_at 14012 Eva1 4 - down 344 SQ only antigen 1 0.340728 0.850813 1.1E-05 0.347664 1417375_at 22145 Tuba4 4 - down 344 SQ only tubulin, alpha 4 0.399264 0.732308 0.0069 0.346784 RIKEN cDNA 1442824_at 399593 8030497I03Rik4 - down 344 SQ only 8030497I03 gene 0.1045 0.631634 0.00499 0.345966

sortilin-related receptor, LDLR class 1453003_at 20660 Sorl1 4 - down 344 SQ only A repeats-containing 0.635364 0.947106 0.00804 0.345099 sphingomyelin phosphodiesterase, 1417300_at 100340 Smpdl3b 4 - down 344 SQ only acid-like 3B 0.218393 0.819625 2.2E-06 0.344781 intraflagellar transport 172 homolog 1423068_at 67661 Ift172 4 - down 344 SQ only (Chlamydomonas) 0.081523 0.744952 8.9E-05 0.344068 RIKEN cDNA 9130022K13 gene /// similar to apolipoprotein L, 3 1453080_at 672691 // 9130022K13Ri 4 - down 344 SQ only (predicted) 0.53123 1.372128 0.00131 0.342137 RIKEN cDNA 1452799_at 75578 2310009E04Ri 4 - down 344 SQ only 2310009E04 gene 0.679587 0.951864 0.00035 0.341249 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 1420508_at 20350 Sema3f 4 - down 344 SQ only (semaphorin) 3 F 0.99263 0.989406 0.00313 0.34115 1434436_at 75746 Morc4 4 - down 344 SQ only microrchidia 4 0.254363 1.2619 0.00696 0.341089 epithelial V-like 1416236_a_at 14012 Eva1 4 - down 344 SQ only antigen 1 0.407653 0.873136 3.3E-05 0.33991 polo-like kinase 2 1427005_at 20620 Plk2 4 - down 344 SQ only (Drosophila) 0.012455 0.635165 0.00106 0.335515 protease, serine, 16 1448355_at 54373 Prss16 4 - down 344 SQ only (thymus) 0.340089 1.37085 0.00018 0.335044 dapper homolog 2, antagonist of beta- 1437929_at 240025 Dact2 4 - down 344 SQ only catenin (xenopus) 0.553775 1.92744 0.00115 0.334522 TBC1 domain family, 1447016_at 57915 Tbc1d1 4 - down 344 SQ only member 1 0.473638 0.819935 0.00523 0.333948

Transcribed locus, strongly similar to NP_035188.1 platelet derived growth factor receptor, alpha polypeptide [Mus 1440527_at ------4 - down 344 SQ only musculus] 0.000119 0.587063 0.0039 0.332027 RIKEN cDNA 1455239_at 320802 6330512M04R 4 - down 344 SQ only 6330512M04 gene 0.751198 1.135346 7.6E-05 0.331978 phospholipase C, 1426926_at 234779 Plcg2 4 - down 344 SQ only gamma 2 0.296667 1.309784 0.00074 0.331673 1422782_s_at 142980 Tlr3 4 - down 344 SQ only toll-like receptor 3 0.005038 0.62674 0.0003 0.331351 ATPase, H+ transporting, lysosomal V0 1448211_at 76252 Atp6v0e2 4 - down 344 SQ only subunit E2 0.173871 0.681682 0.00212 0.331104 tyrosine kinase, non- 1422721_at 83813 Tnk1 4 - down 344 SQ only receptor, 1 0.525084 0.934534 1.8E-05 0.330224 potassium voltage- gated channel, Isk- related subfamily, 1441035_at 16509 Kcne1 4 - down 344 SQ only member 1 0.114035 1.496679 0.00772 0.328564 tripartite motif 1451916_s_at 69097 Trim15 4 - down 344 SQ only protein 15 0.182873 0.698961 0.00059 0.328303

caspase recruitment domain family, 1449491_at 105844 Card10 4 - down 344 SQ only member 10 0.152071 0.653484 0.00134 0.325661 tetratricopeptide 1455649_at 69480 Ttc9 4 - down 344 SQ only repeat domain 9 0.676581 1.114325 2.2E-05 0.325592 RIKEN cDNA 1435981_at 320937 E430014L09Ri 4 - down 344 SQ only E430014L09 gene 0.929187 1.136663 0.00075 0.325137 1416916_at 13710 Elf3 4 - down 344 SQ only E74-like factor 3 0.470645 0.756712 0.00705 0.323956 RAB11 family interacting protein 5 1427405_s_at 52055 Rab11fip5 4 - down 344 SQ only (class I) 0.949655 0.945269 0.00363 0.323292 transmembrane 1426436_at 233806 Tmem159 4 - down 344 SQ only protein 159 0.374151 0.902298 0.00015 0.323036 UDP- GlcNAc:betaGal beta-1,3-N- acetylglucosaminyltr 1436321_at 227327 B3gnt7 4 - down 344 SQ only ansferase 7 0.810953 1.045285 0.00341 0.322826

solute carrier family 1425109_at 213603 Slc44a3 4 - down 344 SQ only 44, member 3 0.335139 0.863147 0.00051 0.321915 cadherin EGF LAG seven-pass G-type 1418925_at 12614 Celsr1 4 - down 344 SQ only receptor 1 0.041943 0.597564 0.00991 0.321585 transmembrane 1426302_at 214523 Tmprss4 4 - down 344 SQ only protease, serine 4 0.339073 1.143612 7.9E-06 0.318361

potassium inwardly- rectifying channel, subfamily J, member 1419601_at 16513 Kcnj10 4 - down 344 SQ only 10 0.203385 0.803988 0.00016 0.314783 RIKEN cDNA 1430517_at 75173 4930544O15R 4 - down 344 SQ only 4930544O15 gene 0.815766 1.047658 0.00709 0.313207 RIKEN cDNA 1429953_at 70134 2210011C24Ri4 - down 344 SQ only 2210011C24 gene 0.432317 1.291342 0.00596 0.312123 protease, serine, 8 1418320_at 76560 Prss8 4 - down 344 SQ only (prostasin) 0.202498 1.305939 0.00082 0.311578 ligand of numb- 1450251_a_at 16924 Lnx1 4 - down 344 SQ only protein X 1 0.319131 0.802447 0.00084 0.310447 1424409_at 71908 Cldn23 4 - down 344 SQ only claudin 23 0.237656 0.730486 0.00069 0.310063 cAMP responsive element binding 1457222_at 231991 Creb5 4 - down 344 SQ only protein 5 0.019078 0.59065 0.00025 0.308177 wingless-related MMTV integration 1420892_at 22422 Wnt7b 4 - down 344 SQ only site 7B 0.014683 0.657485 0.00021 0.307213 tetratricopeptide repeat, ankyrin repeat and coiled- 1436513_at 77097 Tanc2 4 - down 344 SQ only coil containing 2 0.360443 0.798859 0.00473 0.306066 DNA segment, Chr 4, ERATO Doi 58, 1448089_at 52054 D4Ertd58e 4 - down 344 SQ only expressed 0.281292 0.734177 0.00779 0.305839 OVO homolog-like 1 1419051_at 18426 Ovol1 4 - down 344 SQ only (Drosophila) 0.479606 0.866529 0.00045 0.305545 microfibrillar- associated protein 3- 1441481_at 71306 Mfap3l 4 - down 344 SQ only like 0.097635 0.74076 4.5E-05 0.305417 mitogen-activated protein kinase- activated protein 1434815_a_at 102626 Mapkapk3 4 - down 344 SQ only kinase 3 0.1944 1.388857 0.00051 0.305168 1417047_at 192212 Prom2 4 - down 344 SQ only prominin 2 0.448618 1.10211 0.00257 0.303054 1446649_at 212285 Centd1 4 - down 344 SQ only Centaurin, delta 1 0.058665 0.613236 0.0003 0.30256

G-protein signalling modulator 3 (AGS3- 1418396_at 106512 Gpsm3 4 - down 344 SQ only like, C. elegans) 0.583601 0.904524 0.00093 0.298364 dystrophia myotonica-protein 1434944_at 13400 Dmpk 4 - down 344 SQ only kinase 0.510507 0.890821 0.00129 0.29793 cDNA sequence 1451498_at 227618 BC004853 4 - down 344 SQ only BC004853 0.028416 0.61698 0.00017 0.297782

transmembrane protein with EGF-like and two follistatin- 1426649_at 230157 Tmeff1 4 - down 344 SQ only like domains 1 0.551942 0.878677 0.00146 0.2959 1427398_at 140474 Muc4 4 - down 344 SQ only mucin 4 0.318428 0.822692 2.9E-06 0.294497 fatty acid binding 1416022_at 16592 Fabp5 4 - down 344 SQ only protein 5, epidermal 0.245932 1.185545 0.00066 0.293966

ribose 5-phosphate 1418337_at 19895 Rpia 4 - down 344 SQ only isomerase A 0.27556 0.908257 5.2E-06 0.293775 RIKEN cDNA 1430674_at 69428 1700016C15Ri4 - down 344 SQ only 1700016C15 gene 0.671315 1.006753 0.00533 0.29328 tumor-associated calcium signal 1423323_at 56753 Tacstd2 4 - down 344 SQ only transducer 2 0.522448 1.472926 3.8E-05 0.292665

transmembrane protein with EGF-like and two follistatin- 1441890_x_at 230157 Tmeff1 4 - down 344 SQ only like domains 1 0.417042 0.880028 8.2E-05 0.292465 Rho GTPase- 1438451_at 330914 Grit 4 - down 344 SQ only activating protein 0.146569 0.614454 0.00826 0.288233

myeloid ecotropic viral integration site- related gene 2 /// similar to Homeobox protein Meis3 (Meis1- 1423984_a_at 17537 /// Mrg2 /// LOC674 - down 344 SQ only related protein 2) 0.321423 1.118008 0.00048 0.285935

1425558_at 232943 Klc3 4 - down 344 SQ only kinesin light chain 3 0.000332 0.65992 2.4E-05 0.284744 radial spokehead- 1432579_at 66832 Rshl2a 4 - down 344 SQ only like 2A 0.0618 0.596473 0.0011 0.284561 cDNA sequence 1455872_at 219148 BC065085 4 - down 344 SQ only BC065085 0.071918 0.682625 0.00135 0.283245 1451786_at 224116 Muc20 4 - down 344 SQ only mucin 20 0.040006 0.654285 4.2E-05 0.278912 pleckstrin homology domain containing, family H (with MyTH4 domain) 1435053_s_at 211945 Plekhh1 4 - down 344 SQ only member 1 0.872152 1.029461 0.00026 0.278018 RIKEN cDNA 1428303_at 72014 1500005I02Rik4 - down 344 SQ only 1500005I02 gene 0.95831 1.055708 0.00077 0.276734 RIKEN cDNA 1434094_at 230678 6330530A05Ri 4 - down 344 SQ only 6330530A05 gene 0.341332 0.860294 0.00205 0.275696 BH3 interacting domain death 1417045_at 12122 Bid 4 - down 344 SQ only agonist 0.753473 0.93965 0.00017 0.275325 1417957_a_at 66805 Tspan1 4 - down 344 SQ only tetraspanin 1 0.816203 1.060341 3.8E-05 0.274934 chemokine (C-X-C 1418480_at 57349 Cxcl7 4 - down 344 SQ only motif) ligand 7 0.042251 0.548524 0.00984 0.270975

1425028_a_at 22004 Tpm2 4 - down 344 SQ only tropomyosin 2, beta 0.035043 0.565176 0.00031 0.270236

Rho guanine nucleotide exchange 1424250_a_at 71704 Arhgef3 4 - down 344 SQ only factor (GEF) 3 0.089134 0.782165 0.00018 0.269266 ATP-binding cassette, sub-family G (WHITE), member 1419393_at 27409 Abcg5 4 - down 344 SQ only 5 0.369286 1.355239 0.00347 0.268427 lymphocyte antigen 1439773_at 17069 Ly6e 4 - down 344 SQ only 6 complex, locus E 0.117895 0.611963 0.00021 0.26737 Enabled homolog 1442223_at 13800 Enah 4 - down 344 SQ only (Drosophila) 0.597775 0.768497 0.00586 0.26673 1450470_at ------4 - down 344 SQ only --- 0.031638 0.700137 0.00017 0.26533 tribbles homolog 2 1426640_s_at 217410 Trib2 4 - down 344 SQ only (Drosophila) 0.813245 0.9806 2.1E-05 0.263497 1450009_at 17002 Ltf 4 - down 344 SQ only lactotransferrin 0.668187 1.648744 0.00075 0.261783 cDNA sequence 1424477_at 231832 BC019731 4 - down 344 SQ only BC019731 0.036797 0.774116 0.00047 0.261295 CDC42 effector protein (Rho 1450700_at 260409 Cdc42ep3 4 - down 344 SQ only GTPase binding) 3 0.134653 0.542414 0.00417 0.258952

receptor accessory 1424386_at 225362 Reep2 4 - down 344 SQ only protein 2 0.175139 0.732873 0.00117 0.258642

lymphocyte antigen 1454071_at 76486 Ly6k 4 - down 344 SQ only 6 complex, locus K 0.382023 0.853276 0.00152 0.25557 Lemur tyrosine 1439871_at 231876 Lmtk2 4 - down 344 SQ only kinase 2 0.261286 0.692475 0.00507 0.255278

1449577_x_at 22004 Tpm2 4 - down 344 SQ only tropomyosin 2, beta 0.134194 0.597009 0.00109 0.254762 RIKEN cDNA 1443889_at 105892 9030619P08Ri 4 - down 344 SQ only 9030619P08 gene 0.099849 0.611047 0.00015 0.254475 adenylate kinase 3 1450387_s_at 11639 Ak3l1 4 - down 344 SQ only alpha-like 1 0.004032 0.566166 9.6E-05 0.252701 chemokine (C-X-C 1419209_at 14825 Cxcl1 4 - down 344 SQ only motif) ligand 1 0.055736 0.584504 0.00832 0.252556 1421746_a_at 50760 Fbxo17 4 - down 344 SQ only F-box protein 17 0.070758 1.396631 0.00033 0.25193 cytotoxic T lymphocyte- associated protein 2 1448471_a_at 13024 Ctla2a 4 - down 344 SQ only alpha 0.630374 1.034644 0.00321 0.251307 1425536_at 20908 Stx3 4 - down 344 SQ only syntaxin 3 0.335529 0.892999 3.7E-07 0.250748 prostaglandin- endoperoxide 1436448_a_at 19224 Ptgs1 4 - down 344 SQ only synthase 1 0.400977 0.749326 0.00441 0.24996 RIKEN cDNA 1453275_at 75577 2310002L13Ri 4 - down 344 SQ only 2310002L13 gene 0.142855 0.746641 0.00081 0.248759 RIKEN cDNA 1435571_at 319742 A530065I17Rik4 - down 344 SQ only A530065I17 gene 0.282118 0.82749 7.2E-05 0.246024

platelet derived 1449187_at 18590 Pdgfa 4 - down 344 SQ only growth factor, alpha 0.167447 0.623334 0.00119 0.245285

interferon regulatory 1418301_at 54139 Irf6 4 - down 344 SQ only factor 6 0.299336 1.269225 0.00044 0.244599

pleckstrin homology- like domain, family 1417837_at 22113 Phlda2 4 - down 344 SQ only A, member 2 0.742397 1.123155 0.00393 0.244028 1420712_a_at 15451 Hpn 4 - down 344 SQ only hepsin 0.644291 0.934337 0.00016 0.244021

cellular retinoic acid 1451191_at 12904 Crabp2 4 - down 344 SQ only binding protein II 0.223135 0.586774 0.00387 0.243698 Casitas B-lineage 1422666_at 80794 Cblc 4 - down 344 SQ only lymphoma c 0.855165 0.995617 2.6E-05 0.243618 grainyhead-like 2 1429086_at 252973 Grhl2 4 - down 344 SQ only (Drosophila) 0.168312 0.770498 2.9E-05 0.243197 1434873_a_at 216859 Centb1 4 - down 344 SQ only centaurin, beta 1 0.22591 0.78074 1.7E-05 0.241877 elongation factor RNA polymerase II- 1442514_a_at 269344 Ell3 4 - down 344 SQ only like 3 0.166221 0.736415 0.00022 0.241772 ankyrin repeat 1438408_at 78088 Ankrd56 4 - down 344 SQ only domain 56 0.054509 0.705647 2.1E-05 0.240642 1418831_at 56460 Pkp3 4 - down 344 SQ only plakophilin 3 0.591612 0.938707 0.00014 0.240515

G-protein coupled receptor 88 /// similar to G-protein coupled 1423171_at 64378 /// Gpr88 /// LOC64 - down 344 SQ only receptor 88 0.043428 0.543094 0.00253 0.238223 enabled homolog 1421624_a_at 13800 Enah 4 - down 344 SQ only (Drosophila) 0.008219 0.735934 0.00075 0.235406 RIKEN cDNA 1440176_x_at 75480 1700003F12Ri 4 - down 344 SQ only 1700003F12 gene 0.278987 0.745257 7E-05 0.234381 PR domain 1455925_at 77630 Prdm8 4 - down 344 SQ only containing 8 0.334723 0.779814 0.00901 0.229915 1439878_at 16447 Ivl 4 - down 344 SQ only involucrin 0.681607 1.058538 0.00065 0.229542

solute carrier family 7 (cationic amino acid transporter, y+ 1426069_s_at 224022 Slc7a4 4 - down 344 SQ only system), member 4 0.916313 1.001084 6.4E-06 0.229135 immunoglobulin superfamily, member 1420518_a_at 93842 Igsf9 4 - down 344 SQ only 9 0.21614 0.810226 0.00296 0.226666 1440401_at ------4 - down 344 SQ only --- 0.970611 0.989344 0.00116 0.219559

16 days embryo head cDNA, RIKEN full-length enriched library, clone:C130060L08 product:unclassifiabl e, full insert 1438894_at ------4 - down 344 SQ only sequence 0.045137 0.498966 0.00071 0.218063 1425530_a_at 20908 Stx3 4 - down 344 SQ only syntaxin 3 0.524741 0.904057 0.00056 0.217993 calcium/calmodulin- dependent protein 1426389_at 227541 Camk1d 4 - down 344 SQ only kinase ID 0.08023 0.573964 5.5E-05 0.216966 1452291_at 212285 Centd1 4 - down 344 SQ only centaurin, delta 1 0.089363 0.699286 1.9E-05 0.216525 1448745_s_at 16939 Lor 4 - down 344 SQ only loricrin 0.800769 1.626715 0.00838 0.215353 Trp53 inducible 1453041_at 71345 Trp53i5 4 - down 344 SQ only protein 5 0.888311 1.040756 9.1E-06 0.215141 RIKEN cDNA 1429844_at 69665 2310043J07Rik4 - down 344 SQ only 2310043J07 gene 0.016142 0.533807 1.5E-05 0.212896

DNA segment, Chr 10, Brigham & Women's Genetics 1435050_at 215821 D10Bwg1379e 4 - down 344 SQ only 1379 expressed 0.024692 0.488132 0.00391 0.21219 transmembrane channel-like gene 1427178_at 353499 Tmc4 4 - down 344 SQ only family 4 0.758105 1.022408 8.9E-06 0.210825 RIKEN cDNA 1436825_a_at 235973 A630095E13R 4 - down 344 SQ only A630095E13 gene 0.204271 0.716966 5E-05 0.210356

1420352_at 70835 Prss22 4 - down 344 SQ only protease, serine, 22 0.046181 0.646901 0.00134 0.209324 RIKEN cDNA 1417798_at 69073 1810019J16Rik4 - down 344 SQ only 1810019J16 gene 0.921105 1.014954 0.00017 0.208771 SERTA domain 1454877_at 214791 Sertad4 4 - down 344 SQ only containing 4 0.148245 0.733604 0.00015 0.207913 RIKEN cDNA 1450532_at 67859 2310002J15Rik4 - down 344 SQ only 2310002J15 gene 0.766706 0.962434 6.2E-06 0.206453 1431821_a_at 67425 Eps8l1 4 - down 344 SQ only EPS8-like 1 0.008999 0.627369 0.00031 0.205183

myelin and lymphocyte protein, T-cell differentiation 1432558_a_at 17153 Mal 4 - down 344 SQ only protein 0.133582 0.585374 0.00531 0.203342 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 1434606_at 13867 Erbb3 4 - down 344 SQ only (avian) 0.323625 0.895736 2.9E-06 0.203016

inositol (myo)-1(or 4)- 1430495_at 55980 Impa1 4 - down 344 SQ only monophosphatase 1 0.541885 1.404751 0.00929 0.199711

expressed sequence 1424930_s_at 213956 AW544981 4 - down 344 SQ only AW544981 0.207052 0.855732 3.6E-05 0.198147

histidine rich calcium binding protein /// transcription factor 1426048_s_at 15464 /// Hrc /// Tcfap2a 4 - down 344 SQ only AP-2, alpha 0.262996 1.503471 0.00529 0.195901 solute carrier family 4, sodium bicarbonate transporter-like, 1434867_at 269356 Slc4a11 4 - down 344 SQ only member 11 0.631825 0.914349 5E-05 0.19347 RIKEN cDNA 1428739_at 69638 2310040A07Ri 4 - down 344 SQ only 2310040A07 gene 0.036671 0.567006 0.00012 0.192422

MARVEL (membrane- associating) domain 1453264_at 73608 Marveld3 4 - down 344 SQ only containing 3 0.944151 1.035237 0.00017 0.191982 RIKEN cDNA 1443945_at 242574 C130073F10R 4 - down 344 SQ only C130073F10 gene 0.537573 0.915811 7E-05 0.187715

plasminogen 1422139_at 18792 Plau 4 - down 344 SQ only activator, urokinase 0.226519 0.75064 0.00035 0.187542 transmembrane 1436212_at 213068 Tmem71 4 - down 344 SQ only protein 71 0.020333 0.474967 8.1E-05 0.186881 RIKEN cDNA 1427521_a_at 226245 9930023K05Ri 4 - down 344 SQ only 9930023K05 gene 0.125166 0.608972 0.00019 0.186341 Expressed sequence 1446966_at 328258 AU042651 4 - down 344 SQ only AU042651 0.12233 0.56944 0.00099 0.186272 poliovirus receptor- 1428701_at 71740 Pvrl4 4 - down 344 SQ only related 4 0.961627 0.994679 6.9E-05 0.186016 cDNA sequence 1451601_a_at 216892 BC011467 4 - down 344 SQ only BC011467 0.789412 0.986577 6.8E-08 0.184776

solute carrier family 1416596_at 70129 Slc44a4 4 - down 344 SQ only 44, member 4 0.1832 0.756919 1.4E-05 0.18457 cytotoxic T lymphocyte- associated protein 2 1452352_at 13025 Ctla2b 4 - down 344 SQ only beta 0.4435 1.079046 0.00015 0.18318

solute carrier organic anion transporter 1418030_at 108116 Slco3a1 4 - down 344 SQ only family, member 3a1 0.034816 0.526408 4E-05 0.181922 1419700_a_at 19126 Prom1 4 - down 344 SQ only prominin 1 0.672211 1.534431 9.6E-07 0.181767

Transcribed locus, weakly similar to NP_570953.1 CAMP 1449625_at ------4 - down 344 SQ only [Mus musculus] 0.036542 0.590221 1.3E-05 0.176827 ectonucleoside triphosphate diphosphohydrolase 1434049_at 215446 Entpd3 4 - down 344 SQ only 3 0.823313 1.038095 4.5E-05 0.176394 1434559_at 20908 Stx3 4 - down 344 SQ only syntaxin 3 0.638045 0.898011 4E-05 0.175122

expressed sequence 1455172_at 105596 AU020094 4 - down 344 SQ only AU020094 0.241388 0.884932 6.2E-05 0.17489

microtubule- 1421835_at 17761 Mtap7 4 - down 344 SQ only associated protein 7 0.298024 1.288558 0.00023 0.174642

potassium channel, subfamily K, member 1455896_a_at 16525 Kcnk1 4 - down 344 SQ only 1 0.613365 1.131046 0.00024 0.17447 1421836_at ------4 - down 344 SQ only --- 0.33488 1.17544 6.1E-06 0.174223

T-cell receptor gamma chain /// T cell receptor gamma chain /// region containing T-cell receptor gamma chain; T-cell receptor 1422188_s_at 110067 // Tcrg /// LOC67 4 - down 344 SQ only gamma, variable 4 0.235934 0.525791 0.00417 0.172832

solute carrier family 7 (cationic amino acid transporter, y+ 1436776_x_at 224022 Slc7a4 4 - down 344 SQ only system), member 4 0.931207 1.048818 0.00048 0.170745 C1q and tumor necrosis factor 1422606_at 81799 C1qtnf3 4 - down 344 SQ only related protein 3 0.592332 1.120494 0.00407 0.169217

CUB domain 1427095_at 109332 Cdcp1 4 - down 344 SQ only containing protein 1 0.360459 0.836345 0.00018 0.168519

receptor (calcitonin) activity modifying 1417481_at 51801 Ramp1 4 - down 344 SQ only protein 1 0.006599 0.49659 4.5E-07 0.167809

serine (or cysteine) peptidase inhibitor, 1438856_x_at 20724 Serpinb5 4 - down 344 SQ only clade B, member 5 0.168348 1.938067 0.00036 0.165336 G protein-coupled 1420364_at 84111 Gpr87 4 - down 344 SQ only receptor 87 0.321953 0.78194 2.3E-05 0.164107 apolipoprotein B48 1420382_at 171504 Apob48r 4 - down 344 SQ only receptor 0.581965 1.137706 2.3E-06 0.162734 1422222_at 16447 Ivl 4 - down 344 SQ only involucrin 0.374331 1.245406 0.00858 0.16259 adenosine A2a 1427519_at 11540 Adora2a 4 - down 344 SQ only receptor 0.39954 0.786868 4.6E-05 0.16185 transmembrane 1433579_at 238257 Tmem30b 4 - down 344 SQ only protein 30B 0.008007 0.570462 2.9E-07 0.16112

myelin and lymphocyte protein, T-cell differentiation 1417275_at 17153 Mal 4 - down 344 SQ only protein 0.084304 0.645827 0.00092 0.160904

cytotoxic T lymphocyte- associated protein 2 alpha /// cytotoxic T lymphocyte- associated protein 2 1416811_s_at 13024 /// Ctla2a /// Ctla2 4 - down 344 SQ only beta 0.43324 1.101317 0.00173 0.16087 microfibrillar- associated protein 3- 1428804_at 71306 Mfap3l 4 - down 344 SQ only like 0.534704 0.907038 1.9E-06 0.158918 RIKEN cDNA 1436863_at 66931 1700010I14Rik4 - down 344 SQ only 1700010I14 gene 0.337811 0.580539 0.00514 0.157504 1426151_a_at 20908 Stx3 4 - down 344 SQ only syntaxin 3 0.601178 1.138573 0.00115 0.156608

Centrosome and spindle pole 1457971_at 211660 Cspp1 4 - down 344 SQ only associated protein 1 0.106483 0.506677 0.00496 0.156471

lymphocyte antigen 1450562_at 17071 Ly6f 4 - down 344 SQ only 6 complex, locus F 0.137462 0.709888 0.00148 0.155429

cytochrome P450, family 11, subfamily 1439947_at 13070 Cyp11a1 4 - down 344 SQ only a, polypeptide 1 0.365963 1.675356 0.00187 0.152601 glycoprotein A33 1454247_a_at 59290 Gpa33 4 - down 344 SQ only (transmembrane) 0.633037 1.105901 0.00867 0.150987 1426911_at 13506 Dsc2 4 - down 344 SQ only desmocollin 2 0.932959 0.987622 0.00081 0.149659 16 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:9630013F18 product:unclassifiabl e, full insert 1436359_at ------4 - down 344 SQ only sequence 0.446032 1.317975 0.00224 0.148698 similar to SP140 nuclear body protein 1425078_x_at 620078 LOC620078 4 - down 344 SQ only (predicted) 0.272368 0.776293 0.00445 0.148157 1426181_a_at 93672 Il24 4 - down 344 SQ only interleukin 24 0.630782 1.152167 0.0006 0.146722

FXYD domain- containing ion 1418374_at 17178 Fxyd3 4 - down 344 SQ only transport regulator 3 0.056353 0.664639 0.00016 0.145926 1440353_at 78405 Ntf5 4 - down 344 SQ only neurotrophin 5 0.02381 0.565429 3.5E-05 0.142947 lin-7 homolog B (C. 1449172_a_at 22342 Lin7b 4 - down 344 SQ only elegans) 0.186529 0.512315 0.00457 0.142215 1435165_at 21367 Cntn2 4 - down 344 SQ only contactin 2 0.143944 0.534617 0.00446 0.141082 amyloid beta (A4) precursor protein binding, family A, 1455369_at 319924 Apba1 4 - down 344 SQ only member 1 0.523586 0.8427 7.3E-05 0.139379 G protein-coupled 1440830_at 224792 Gpr116 4 - down 344 SQ only receptor 116 0.013625 0.487617 1.7E-05 0.139115 RIKEN cDNA 1423933_a_at 76509 1600029D21Ri4 - down 344 SQ only 1600029D21 gene 0.153372 0.511832 0.00142 0.138011 1447299_at ------4 - down 344 SQ only --- 0.002122 0.409488 3.8E-05 0.134543 cDNA sequence 1425108_a_at 207818 BC004728 4 - down 344 SQ only BC004728 0.205463 0.759761 5.3E-05 0.134262

membrane targeting (tandem) C2 domain 1425783_at 74413 Mtac2d1 4 - down 344 SQ only containing 1 0.047341 0.39913 0.00177 0.133001 copine family 1454653_at 211232 Cpne9 4 - down 344 SQ only member IX 0.530453 1.365457 0.00838 0.127727 transmembrane 1424966_at 94346 Tmem40 4 - down 344 SQ only protein 40 0.55866 1.175477 1.7E-05 0.127404 spermatogenesis 1454237_at 75571 Spata9 4 - down 344 SQ only associated 9 0.511225 0.859623 0.0032 0.127357 sialic acid binding Ig- 1421463_at 83382 Siglece 4 - down 344 SQ only like lectin E 0.35365 0.814695 0.00058 0.124073 1419518_at 53857 Tuba8 4 - down 344 SQ only tubulin, alpha 8 0.170016 0.602468 0.00024 0.124033 RIKEN cDNA 1439963_x_at 330577 1700129I04Rik4 - down 344 SQ only 1700129I04 gene 0.731333 0.762081 0.00936 0.12166 1448837_at 22349 Vil1 4 - down 344 SQ only villin 1 0.426372 0.923355 0.00051 0.120864 1434425_at 99681 Tchh 4 - down 344 SQ only trichohyalin 0.788118 0.976338 0.00924 0.120421

ribosomal protein S6 1429759_at 67071 Rps6ka6 4 - down 344 SQ only kinase polypeptide 6 0.387923 1.559264 6.1E-06 0.1188 RIKEN cDNA 1417797_a_at 69073 1810019J16Rik4 - down 344 SQ only 1810019J16 gene 0.675411 0.983255 1.5E-05 0.116378

membrane targeting (tandem) C2 domain 1443933_at 74413 Mtac2d1 4 - down 344 SQ only containing 1 0.043415 0.540353 1.3E-05 0.113506 1449586_at 18772 Pkp1 4 - down 344 SQ only plakophilin 1 0.607842 1.291433 3.3E-05 0.113021 V-set domain containing T cell 1458070_at 242122 Vtcn1 4 - down 344 SQ only activation inhibitor 1 0.475855 0.864526 0.00051 0.109033

receptor accessory 1430128_a_at 70335 Reep6 4 - down 344 SQ only protein 6 0.991797 1.028223 9.3E-05 0.107246

serine (or cysteine) peptidase inhibitor, 1424623_at 20724 Serpinb5 4 - down 344 SQ only clade B, member 5 0.066149 1.92683 3.3E-05 0.098853 nuclear factor, erythroid derived 2, 1417520_at 18025 Nfe2l3 4 - down 344 SQ only like 3 0.058159 0.570676 1.8E-06 0.09561 RIKEN cDNA 1450947_at 66451 2610528J11Rik4 - down 344 SQ only 2610528J11 gene 0.247877 0.842395 2.8E-07 0.09487 mal, T-cell differentiation protein 1427042_at 105853 Mal2 4 - down 344 SQ only 2 0.005637 0.571195 2.1E-06 0.094671 transmembrane 1451546_s_at 94346 Tmem40 4 - down 344 SQ only protein 40 0.358702 1.359956 9.4E-05 0.092926

potassium channel, subfamily K, member 1421852_at 16529 Kcnk5 4 - down 344 SQ only 5 0.009994 0.419366 1E-05 0.091466

ADP- 1423008_at 11871 Art2a 4 - down 344 SQ only ribosyltransferase 2a 0.429142 0.687847 0.00457 0.090798

expressed sequence 1434046_at 433470 AA467197 4 - down 344 SQ only AA467197 0.326084 0.770514 0.00112 0.089979 1422784_at 16687 Krt6a 4 - down 344 SQ only keratin 6A 0.609957 0.888859 0.00179 0.088238 mitogen activated 1448871_at 26415 Mapk13 4 - down 344 SQ only protein kinase 13 0.953891 0.960405 1.6E-05 0.086642 RIKEN cDNA 1418871_a_at 53906 1810007E14Ri 4 - down 344 SQ only 1810007E14 gene 0.385887 0.736346 0.0078 0.086187 NIPA-like domain 1424612_at 223473 Npal2 4 - down 344 SQ only containing 2 0.102216 0.627859 6.3E-06 0.085287 RIKEN cDNA 1440186_s_at 76943 2310020A21Ri 4 - down 344 SQ only 2310020A21 gene 0.038549 0.43077 4.2E-05 0.08147 hook homolog 1 1438018_at 77963 Hook1 4 - down 344 SQ only (Drosophila) 0.01808 0.596867 0.0005 0.080009

peptidoglycan 1449184_at 21946 Pglyrp1 4 - down 344 SQ only recognition protein 1 0.010045 0.444243 3.6E-06 0.079687 diacylglycerol kinase 1442865_at 331374 Dgkk 4 - down 344 SQ only kappa 0.06516 0.401842 6.3E-06 0.079063 tumor-associated calcium signal 1416579_a_at 17075 Tacstd1 4 - down 344 SQ only transducer 1 0.141439 0.885283 0.00017 0.078087 B-box and SPRY 1450131_a_at 192120 Bspry 4 - down 344 SQ only domain containing 0.777376 1.17283 3.6E-07 0.076805 1422008_a_at 11828 Aqp3 4 - down 344 SQ only aquaporin 3 0.095129 0.319732 0.00235 0.076404 1448393_at 53624 Cldn7 4 - down 344 SQ only claudin 7 0.428404 0.931915 3.7E-05 0.075346 hypothetical gene supported by 1439560_x_at 432995 LOC432995 4 - down 344 SQ only BC047216 0.808399 1.071559 3.6E-05 0.07504 1450240_a_at 269589 Sytl1 4 - down 344 SQ only synaptotagmin-like 1 0.178442 0.553927 1.6E-05 0.073997 secreted frizzled- related sequence 1423023_at 54612 Sfrp5 4 - down 344 SQ only protein 5 0.219136 0.570752 7.4E-05 0.073022 1426332_a_at 12739 Cldn3 4 - down 344 SQ only claudin 3 0.892824 0.939905 0.00041 0.071089 nuclear factor, erythroid derived 2, 1453614_a_at 18025 Nfe2l3 4 - down 344 SQ only like 3 0.194523 0.639574 3.5E-05 0.068773

serine (or cysteine) peptidase inhibitor, 1421752_a_at 20724 Serpinb5 4 - down 344 SQ only clade B, member 5 0.220048 1.423218 1.5E-05 0.068036 leucine rich repeat 1427388_at 74249 Lrrc2 4 - down 344 SQ only containing 2 0.892308 1.3357 4.4E-05 0.066414 ets homologous 1419474_a_at 13661 Ehf 4 - down 344 SQ only factor 0.202058 0.783751 2.1E-06 0.064061

serine (or cysteine) peptidase inhibitor, 1441941_x_at 20724 Serpinb5 4 - down 344 SQ only clade B, member 5 0.158128 2.153646 0.00011 0.063505

lymphocyte antigen 1416930_at 17068 Ly6d 4 - down 344 SQ only 6 complex, locus D 0.00594 0.377021 3.6E-05 0.063003 RIKEN cDNA 1452326_at 69047 1810010G06R 4 - down 344 SQ only 1810010G06 gene 0.860029 1.020143 1.7E-07 0.057499 1451701_x_at 12739 Cldn3 4 - down 344 SQ only claudin 3 0.968023 0.9606 0.00012 0.056901 1421799_at 24111 Uts2 4 - down 344 SQ only urotensin 2 0.226232 0.714886 8.9E-07 0.056901 histone deacetylase 1454803_a_at 232232 Hdac11 4 - down 344 SQ only 11 0.688167 1.047199 0.00253 0.054776

potassium channel, subfamily K, member 1448690_at 16525 Kcnk1 4 - down 344 SQ only 1 0.946025 1.041051 0.00016 0.053107 ets homologous 1451375_at 13661 Ehf 4 - down 344 SQ only factor 0.677344 1.129357 2.8E-05 0.050724 grainyhead-like 2 1427046_at 252973 Grhl2 4 - down 344 SQ only (Drosophila) 0.348834 0.862775 1.8E-06 0.043995

membrane targeting (tandem) C2 domain 1451838_a_at 74413 Mtac2d1 4 - down 344 SQ only containing 1 0.01726 0.31586 0.00019 0.041663 suppression of tumorigenicity 14 1418076_at 19143 St14 4 - down 344 SQ only (colon carcinoma) 0.153403 0.784434 2.9E-07 0.040791 adaptor protein complex AP-1, mu 2 1460190_at 11768 Ap1m2 4 - down 344 SQ only subunit 0.521753 1.102229 1.9E-06 0.040369 RIKEN cDNA 1457044_at 238455 4732474O15R 4 - down 344 SQ only 4732474O15 gene 0.358483 1.211392 4.5E-07 0.035927 RIKEN cDNA 1444740_at 108975 4930550L11Ri 4 - down 344 SQ only 4930550L11 gene 0.02684 0.612968 5E-06 0.035583 1418283_at 12740 Cldn4 4 - down 344 SQ only claudin 4 0.472757 0.781982 3.5E-05 0.034887 1434651_a_at 12739 Cldn3 4 - down 344 SQ only claudin 3 0.839647 0.930803 0.00013 0.032568 immunoglobulin superfamily, member 1441420_at 93842 Igsf9 4 - down 344 SQ only 9 0.126477 0.424106 0.00021 0.031766 1460569_x_at 12739 Cldn3 4 - down 344 SQ only claudin 3 0.612891 0.903885 7.4E-05 0.030052 IBR domain 1443252_at 218215 Ibrdc2 4 - down 344 SQ only containing 2 0.720203 1.145437 1.5E-05 0.027925 RIKEN cDNA 4933405I11 gene /// 1438555_x_at 140474 // 4933405I11Rik4 - down 344 SQ only mucin 4 0.306306 0.791642 2.1E-07 0.025127

transmembrane 1458871_at 243084 Tmprss11e 4 - down 344 SQ only protease, serine 11e 0.327518 0.804022 2.2E-05 0.023893 1459299_at 329421 Myo3b 4 - down 344 SQ only myosin IIIB 0.056293 1.585593 4.4E-08 0.022991 1419722_at 259277 Klk8 4 - down 344 SQ only kallikrein 8 0.002394 0.237041 1.1E-05 0.022719

membrane targeting (tandem) C2 domain 1439045_x_at 74413 Mtac2d1 4 - down 344 SQ only containing 1 0.01948 0.276011 6.9E-05 0.022152 laminin, alpha 3 /// similar to Laminin alpha-3 chain precursor (Nicein 1427512_a_at 16774 /// Lama3 /// LOC 4 - down 344 SQ only alpha subunit) 0.99201 1.028483 4.1E-08 0.022037 1423506_a_at 18111 Nnat 4 - down 344 SQ only neuronatin 0.098635 0.406124 0.00013 0.021588

ribosomal protein S6 1429760_at 67071 Rps6ka6 4 - down 344 SQ only kinase polypeptide 6 0.291017 1.555585 7.5E-07 0.019685 RAB25, member RAS oncogene 1417738_at 53868 Rab25 4 - down 344 SQ only family 0.384703 1.149073 3.8E-06 0.015462 RIKEN cDNA 1426268_at 231293 C130090K23R 4 - down 344 SQ only C130090K23 gene 0.007285 0.508716 1.8E-08 0.011398

S100 calcium 1449166_at 66166 S100a14 4 - down 344 SQ only binding protein A14 0.521051 1.132334 4.9E-08 0.011057 RNA binding motif 1454681_at 207920 Rbm35a 4 - down 344 SQ only protein 35A 0.277536 0.809707 5.2E-07 0.002055 Iroquois related homeobox 3 1418517_at 16373 Irx3 5 - up both 393LN, 344 SQ (Drosophila) 0.008509 6.17882 1.7E-06 15.76832 insulinoma- 1455865_at 53626 Insm1 5 - up both 393LN, 344 SQ associated 1 0.000949 9.127033 0.00123 12.00968 RIKEN cDNA 1452609_at 68918 1190005I06Rik5 - up both 393LN, 344 SQ 1190005I06 gene 0.041056 3.749352 0.00253 8.724287 sodium channel, voltage-gated, type 1427495_at 20272 Scn7a 5 - up both 393LN, 344 SQ VII, alpha 0.099714 3.942857 0.00106 8.509244 Iroquois related homeobox 5 1421072_at 54352 Irx5 5 - up both 393LN, 344 SQ (Drosophila) 0.017281 3.344456 4.7E-07 8.267427 1442877_at ------5 - up both 393LN, 344 SQ --- 0.042273 5.025478 0.00032 8.242038

1427004_at 230904 Fbxo2 5 - up both 393LN, 344 SQ F-box only protein 2 0.009313 3.1391 0.08586 7.768211 1447129_at ------5 - up both 393LN, 344 SQ --- 0.003512 2.947289 0.01096 7.298193 transmembrane 4 superfamily member 1448069_at 17112 Tm4sf1 5 - up both 393LN, 344 SQ 1 0.002171 3.465157 0.00014 6.893273 RIKEN cDNA 1437595_at 226040 E030010A14R 5 - up both 393LN, 344 SQ E030010A14 gene 0.01437 3.25268 0.00151 6.815751 1457396_at ------5 - up both 393LN, 344 SQ --- 0.006423 5.188022 0.13046 6.55571 1420241_at ------5 - up both 393LN, 344 SQ --- 0.001566 4.527048 0.31543 6.227202

zinc finger, DHHC 1452656_at 70546 Zdhhc2 5 - up both 393LN, 344 SQ domain containing 2 0.02367 3.273195 0.00014 5.819044 Bcl6 interacting 1452910_at 71458 Bcor 5 - up both 393LN, 344 SQ corepressor 0.000224 3.535118 0.00088 5.490591

Myeloid ecotropic viral integration site- 1447861_x_at 17536 Mrg1 5 - up both 393LN, 344 SQ related gene 1 0.212033 3.221243 0.00294 5.127863 RIKEN cDNA 1440110_at 320983 B130019D13R 5 - up both 393LN, 344 SQ B130019D13 gene 0.075031 3.312457 0.0049 5.036882 lectin, galactose- 1417079_s_at 107753 Lgals2 5 - up both 393LN, 344 SQ binding, soluble 2 0.1643 8.60956 0.00421 4.99925 RIKEN cDNA 1432531_at 77705 9230104L09Ri 5 - up both 393LN, 344 SQ 9230104L09 gene 0.00073 7.530396 0.07494 4.897797 transmembrane 4 superfamily member 1439925_at 17112 Tm4sf1 5 - up both 393LN, 344 SQ 1 0.000377 2.280131 9.2E-06 4.827559 ELMO domain 1443496_at 270162 Elmod1 5 - up both 393LN, 344 SQ containing 1 0.042656 2.69697 0.00555 4.720539

phosphodiesterase 4D interacting 1456413_at 83679 Pde4dip 5 - up both 393LN, 344 SQ protein (myomegalin) 0.004163 2.554605 0.00101 4.66917 uridine 1460059_at 76654 Upp2 5 - up both 393LN, 344 SQ phosphorylase 2 0.027005 3.627753 0.0086 4.639868 cDNA sequence 1440718_at 223433 BC052328 5 - up both 393LN, 344 SQ BC052328 0.0087 2.55791 0.02291 4.391243 cDNA sequence 1437950_at 212326 BC035537 5 - up both 393LN, 344 SQ BC035537 0.0462 4.795617 3.7E-05 4.365106

phosphodiesterase 4D interacting 1433761_at 83679 Pde4dip 5 - up both 393LN, 344 SQ protein (myomegalin) 0.000627 2.145387 8.8E-08 4.304597 1438577_at ------5 - up both 393LN, 344 SQ Transcribed locus 0.039899 4.111938 0.00501 4.238439

matrix 1443412_s_at 17389 Mmp16 5 - up both 393LN, 344 SQ metallopeptidase 16 0.01335 2.219881 0.00282 4.150445 proline-rich 1428706_at 73139 Prr6 5 - up both 393LN, 344 SQ polypeptide 6 0.001017 4.107909 4.2E-05 4.12621 RIKEN cDNA 1428926_at 76291 1110003O08R 5 - up both 393LN, 344 SQ 1110003O08 gene 0.000225 2.90314 0.00011 4.035126 protocadherin beta 1448933_at 93888 Pcdhb17 5 - up both 393LN, 344 SQ 17 0.019295 2.158886 1.9E-05 4.028447

trans-acting 1422914_at 64406 Sp5 5 - up both 393LN, 344 SQ transcription factor 5 0.003506 5.572052 0.20106 3.676856 RIKEN cDNA 1429896_at 74756 5830408B19Ri 5 - up both 393LN, 344 SQ 5830408B19 gene 0.008044 1.999858 7.2E-05 3.592506 RAN binding protein 1435167_at 240614 Ranbp6 5 - up both 393LN, 344 SQ 6 0.01421 2.125245 2.5E-05 3.536488 Myeloid ecotropic viral integration site- 1443926_at 17536 Mrg1 5 - up both 393LN, 344 SQ related gene 1 0.087394 2.671636 0.0088 3.455882 RIKEN cDNA 1440796_at 207686 A330021E22R 5 - up both 393LN, 344 SQ A330021E22 gene 0.013296 3.397989 0.00064 3.432012 1418066_at 12632 Cfl2 5 - up both 393LN, 344 SQ cofilin 2, muscle 0.011725 2.036794 8E-06 3.361247

eukaryotic translation initiation 1449576_at 66235 Eif1ay 5 - up both 393LN, 344 SQ factor 1A, Y-linked 0.000616 3.911584 0.00062 3.196076 RIKEN cDNA 1454548_at 74266 1700039M15R 5 - up both 393LN, 344 SQ 1700039M15 gene 0.257657 3.006051 0.0031 3.189864

protein phosphatase 1, regulatory (inhibitor) subunit 1417990_at 72112 Ppp1r14d 5 - up both 393LN, 344 SQ 14D 0.022739 4.262283 0.00194 3.17341 1459552_at ------5 - up both 393LN, 344 SQ Transcribed locus 0.033953 2.03184 0.00829 3.160578 aldehyde dehydrogenase family 6, subfamily 1448104_at 104776 Aldh6a1 5 - up both 393LN, 344 SQ A1 0.004332 2.174575 0.00024 3.108738 RIKEN cDNA 1454873_at 243372 C130032F08R 5 - up both 393LN, 344 SQ C130032F08 gene 0.026286 2.619604 0.00057 3.051639 ribonuclease P 25 1448845_at 102614 Rpp25 5 - up both 393LN, 344 SQ subunit (human) 0.017855 2.340664 0.00038 3.037092 pantothenate kinase 1418715_at 75735 Pank1 5 - up both 393LN, 344 SQ 1 0.000604 3.401781 0.00038 3.027877 1442740_at ------5 - up both 393LN, 344 SQ --- 0.00017 3.607412 0.00053 3.013251 RIKEN cDNA 1439284_at 320932 E230025E14R 5 - up both 393LN, 344 SQ E230025E14 gene 0.027355 2.636092 0.00191 2.993981 pantothenate kinase 1431028_a_at 75735 Pank1 5 - up both 393LN, 344 SQ 1 0.000213 3.246928 0.00061 2.969353 tripartite motif- 1454650_at 66854 Trim35 5 - up both 393LN, 344 SQ containing 35 0.013284 2.033126 0.00157 2.950831 putative neuronal cell adhesion 1439498_at 19289 Punc 5 - up both 393LN, 344 SQ molecule 0.011748 1.788428 0.00077 2.94361 Signaling molecule 1457207_at 54122 Attp 5 - up both 393LN, 344 SQ ATTP 0.011215 2.795687 0.00854 2.938639 1436002_at ------5 - up both 393LN, 344 SQ Transcribed locus 0.104323 3.323711 0.00768 2.938144 1430236_s_at 76758 Gsdm2 5 - up both 393LN, 344 SQ gasdermin 2 0.001037 2.995413 0.00068 2.93578

purine rich element 1456898_at 19290 Pura 5 - up both 393LN, 344 SQ binding protein A 0.000351 1.964701 0.0006 2.913231 guanine nucleotide binding protein, beta 1419470_at 14696 Gnb4 5 - up both 393LN, 344 SQ 4 0.010439 1.937029 0.00088 2.87253

purine rich element 1453783_at 19290 Pura 5 - up both 393LN, 344 SQ binding protein A 0.01592 2.161153 0.00123 2.866949 RIKEN cDNA 1436051_at 102493 9630007J19Rik5 - up both 393LN, 344 SQ 9630007J19 gene 4.88E-05 2.719166 9.5E-05 2.866427 RIKEN cDNA 1432110_at 74854 4930402F06Ri 5 - up both 393LN, 344 SQ 4930402F06 gene 0.004592 6.045547 0.05673 2.827935 1433968_a_at ------5 - up both 393LN, 344 SQ --- 0.007957 1.903767 0.0012 2.824738 nuclear fragile X mental retardation protein interacting 1428583_at 68564 Nufip2 5 - up both 393LN, 344 SQ protein 2 0.003897 1.786441 0.00126 2.817846 Bcl6 interacting 1428773_s_at 71458 Bcor 5 - up both 393LN, 344 SQ corepressor 0.003561 1.749506 3.4E-05 2.810503

SH3-domain GRB2- 1418012_at 54673 Sh3glb1 5 - up both 393LN, 344 SQ like B1 (endophilin) 0.009956 1.83803 0.0002 2.782481 nuclear receptor 1434515_at 17977 Ncoa1 5 - up both 393LN, 344 SQ coactivator 1 0.000379 2.14204 2.3E-05 2.768369 1448233_at 19122 Prnp 5 - up both 393LN, 344 SQ prion protein 0.00171 2.066766 6.1E-05 2.734762 tripartite motif 1439352_at 94089 Trim7 5 - up both 393LN, 344 SQ protein 7 0.001761 5.285078 0.05767 2.731997

myeloid ecotropic viral integration site- 1457632_s_at 17536 Mrg1 5 - up both 393LN, 344 SQ related gene 1 0.088261 1.864284 0.00098 2.698567 ADP-ribosylation 1435092_at 11861 Arl4a 5 - up both 393LN, 344 SQ factor-like 4A 0.001544 2.000456 0.00223 2.696384 RIKEN cDNA 1458976_at 320842 C230035I16Rik5 - up both 393LN, 344 SQ C230035I16 gene 0.005433 1.745795 0.00026 2.675228

xenotropic and polytropic retrovirus 1437958_at 19775 Xpr1 5 - up both 393LN, 344 SQ receptor 1 0.008541 1.780022 1.5E-05 2.67427 pleckstrin homology domain containing, family G (with RhoGef domain) 1440991_at 213783 Plekhg1 5 - up both 393LN, 344 SQ member 1 0.04925 1.768622 0.00641 2.663955 RIKEN cDNA 1455628_at 319794 6430543G08R 5 - up both 393LN, 344 SQ 6430543G08 gene 0.020697 2.030274 0.00262 2.653185

expressed sequence 1436520_at 382643 AI450948 5 - up both 393LN, 344 SQ AI450948 0.001072 1.763566 0.00069 2.631791 glutathione S- 1448330_at 14862 Gstm1 5 - up both 393LN, 344 SQ transferase, mu 1 0.164548 1.984438 0.0011 2.628917 poly(rC) binding 1417526_at 59093 Pcbp3 5 - up both 393LN, 344 SQ protein 3 0.000924 1.860177 0.00056 2.620235 kinesin family 1455266_at 16574 Kif5c 5 - up both 393LN, 344 SQ member 5C 0.124068 1.911738 0.00012 2.601142 dpy-19-like 1 (C. 1433759_at 244745 Dpy19l1 5 - up both 393LN, 344 SQ elegans) 0.009933 1.970442 0.00012 2.594029 similar to Zinc finger X-linked protein 1455817_x_at 668166 LOC668166 5 - up both 393LN, 344 SQ ZXDB 0.001246 2.65997 0.00083 2.575143 RIKEN cDNA 1455859_at 207686 A330021E22R 5 - up both 393LN, 344 SQ A330021E22 gene 0.037788 2.598228 0.0007 2.554249 ribonucleotide 1416120_at 20135 Rrm2 5 - up both 393LN, 344 SQ reductase M2 0.005524 2.534684 0.01018 2.535085 TSC22 domain 1425281_a_at 14605 Tsc22d3 5 - up both 393LN, 344 SQ family 3 0.005254 2.564879 0.03792 2.534199 spire homolog 1 1454962_at 68166 Spire1 5 - up both 393LN, 344 SQ (Drosophila) 0.010076 1.73077 0.00014 2.501721 1418770_at 12481 Cd2 5 - up both 393LN, 344 SQ CD2 antigen 0.076367 1.890587 0.00835 2.484607 glutathione S- 1416416_x_at 14862 Gstm1 5 - up both 393LN, 344 SQ transferase, mu 1 0.160943 1.906095 0.00167 2.481232 1457978_at 347722 Centg2 5 - up both 393LN, 344 SQ Centaurin, gamma 2 0.004478 2.277802 0.02075 2.480893 tubulin tyrosine ligase-like family, 1455780_at 237930 Ttll6 5 - up both 393LN, 344 SQ member 6 0.001898 3.123879 0.00473 2.480033 PDZ domain 1439088_at 107368 Pdzd8 5 - up both 393LN, 344 SQ containing 8 0.009173 2.199539 0.00365 2.475895 RIKEN cDNA 1443648_at 77391 9530003O04R 5 - up both 393LN, 344 SQ 9530003O04 gene 0.038847 1.668458 0.00503 2.470315

1443407_at 24017 Rnf13 5 - up both 393LN, 344 SQ ring finger protein 13 0.093493 2.208344 0.00912 2.466498 transcription elongation factor A 1424634_at 237052 Tceal1 5 - up both 393LN, 344 SQ (SII)-like 1 0.14357 1.909176 0.00155 2.461878 1422837_at 64929 Scel 5 - up both 393LN, 344 SQ sciellin 0.026787 1.681883 0.00021 2.422175 1433592_at 12313 Calm1 5 - up both 393LN, 344 SQ calmodulin 1 0.065 1.637144 0.00335 2.404091 protein tyrosine phosphatase, non- 1425198_at 19255 Ptpn2 5 - up both 393LN, 344 SQ receptor type 2 0.000416 2.272741 0.00196 2.398072 ribonucleotide 1448226_at 20135 Rrm2 5 - up both 393LN, 344 SQ reductase M2 0.003009 2.174033 0.00062 2.394602 TSC22 domain 1420772_a_at 14605 Tsc22d3 5 - up both 393LN, 344 SQ family 3 0.001533 2.397646 0.00624 2.393083 protein inhibitor of 1455486_at 56469 Pias1 5 - up both 393LN, 344 SQ activated STAT 1 0.141411 1.605285 0.00661 2.381734 transmembrane 1422587_at 56277 Tmem45a 5 - up both 393LN, 344 SQ protein 45a 0.011021 1.559915 0.0002 2.370426 B lymphoma Mo- MLV insertion region 1448733_at 12151 Bmi1 5 - up both 393LN, 344 SQ 1 0.002911 2.104276 6.3E-05 2.357401

ariadne ubiquitin- conjugating enzyme E2 binding protein homolog 1 1441022_at 23806 Arih1 5 - up both 393LN, 344 SQ (Drosophila) 0.023962 1.591043 8E-05 2.350416 RIKEN cDNA 1428910_at 69551 2310022B05Ri 5 - up both 393LN, 344 SQ 2310022B05 gene 0.000768 2.015029 1.8E-06 2.338032 lysosomal acid 1450872_s_at 16889 Lip1 5 - up both 393LN, 344 SQ lipase 1 0.023397 1.564813 0.00287 2.329378 short coiled-coil 1430999_a_at 56367 Scoc 5 - up both 393LN, 344 SQ protein 0.000487 2.658199 0.00121 2.329094

Adult male hippocampus cDNA, RIKEN full-length enriched library, clone:C630020O05 product:unclassifiabl e, full insert 1441388_at ------5 - up both 393LN, 344 SQ sequence 0.006091 2.095438 0.00158 2.323903

male-specific lethal 2- 1429108_at 77853 Msl2l1 5 - up both 393LN, 344 SQ like 1 (Drosophila) 0.013399 2.071479 0.00139 2.308208 guanine nucleotide binding protein, beta 1419469_at 14696 Gnb4 5 - up both 393LN, 344 SQ 4 0.015008 1.610607 0.00239 2.30701 RIKEN cDNA 1435348_at 399585 D930009K15R 5 - up both 393LN, 344 SQ D930009K15 gene 0.002139 1.857401 0.00229 2.30141

10 days neonate cerebellum cDNA, RIKEN full-length enriched library, clone:B930082K12 product:unclassifiabl e, full insert 1440027_at ------5 - up both 393LN, 344 SQ sequence 0.001774 2.981827 0.00307 2.294247 ornithine 1416452_at 18242 Oat 5 - up both 393LN, 344 SQ aminotransferase 0.013871 1.723338 0.00053 2.274204 RIKEN cDNA 1452889_at 76429 2310007H09Ri5 - up both 393LN, 344 SQ 2310007H09 gene 0.001203 3.146067 0.0018 2.273258 FYVE, RhoGEF and PH domain 1455337_at 224014 Fgd4 5 - up both 393LN, 344 SQ containing 4 0.004044 2.039461 0.00017 2.252083

serine (or cysteine) peptidase inhibitor, 1422804_at 20708 Serpinb6b 5 - up both 393LN, 344 SQ clade B, member 6b 0.003112 1.760282 0.03038 2.242006

ATP-binding cassette, sub-family 1434474_at 217265 Abca5 5 - up both 393LN, 344 SQ A (ABC1), member 5 0.000925 1.620759 4.3E-05 2.23976 short coiled-coil 1416267_at 56367 Scoc 5 - up both 393LN, 344 SQ protein 2.53E-05 2.246544 3E-06 2.225134 RIKEN cDNA 1452762_at 71506 8430436O14R 5 - up both 393LN, 344 SQ 8430436O14 gene 0.099409 1.567032 0.00401 2.222797

SH3-domain GRB2- 1418011_a_at 54673 Sh3glb1 5 - up both 393LN, 344 SQ like B1 (endophilin) 0.027079 1.632887 0.00157 2.217046 RIKEN cDNA 1437041_at 66625 5730406M06R 5 - up both 393LN, 344 SQ 5730406M06 gene 0.008606 2.070402 0.01568 2.21393 cytochrome P450, family 1, subfamily b, 1416612_at 13078 Cyp1b1 5 - up both 393LN, 344 SQ polypeptide 1 0.034981 1.876048 0.0059 2.210112

phosphatidylinositol 3-kinase, catalytic, 1429435_x_at 18706 Pik3ca 5 - up both 393LN, 344 SQ alpha polypeptide 0.057376 1.628585 0.00143 2.209492 1420290_at ------5 - up both 393LN, 344 SQ Transcribed locus 0.006888 2.707757 0.12588 2.208058 TSC22 domain 1425557_x_at 14605 Tsc22d3 5 - up both 393LN, 344 SQ family 3 0.000227 2.130696 0.00226 2.20562 ribonucleotide 1434437_x_at 20135 Rrm2 5 - up both 393LN, 344 SQ reductase M2 0.002892 1.895135 0.00096 2.204196 WD repeat and FYVE domain 1428517_at 72145 Wdfy3 5 - up both 393LN, 344 SQ containing 3 0.009043 1.691046 0.00209 2.202161

hexose-6-phosphate dehydrogenase (glucose 1- 1452145_at 100198 H6pd 5 - up both 393LN, 344 SQ dehydrogenase) 0.0289 1.672784 0.00692 2.201726 translocation protein 1455698_at 69276 Tloc1 5 - up both 393LN, 344 SQ 1 0.003839 2.072414 0.01013 2.201513 pericentriolar 1436908_at 18536 Pcm1 5 - up both 393LN, 344 SQ material 1 0.000226 1.801784 0.00667 2.192059 FUN14 domain 1460434_at 67391 Fundc2 5 - up both 393LN, 344 SQ containing 2 0.004416 2.64941 0.01109 2.188083 1419754_at 17918 Myo5a 5 - up both 393LN, 344 SQ myosin Va 4.9E-06 1.943801 2.3E-05 2.155768

glutamic pyruvate transaminase (alanine 1455007_s_at 108682 Gpt2 5 - up both 393LN, 344 SQ aminotransferase) 2 0.000285 1.985586 0.00068 2.154117 similar to signal recognition particle 1445334_at 665155 LOC665155 5 - up both 393LN, 344 SQ 54 0.000307 2.529788 0.00069 2.144109 cDNA sequence 1434143_at 234776 BC060631 5 - up both 393LN, 344 SQ BC060631 0.002043 4.396869 0.00127 2.137449 cytochrome P450, family 1, subfamily b, 1416613_at 13078 Cyp1b1 5 - up both 393LN, 344 SQ polypeptide 1 0.072017 1.905169 0.00248 2.136974 RIKEN cDNA 1457779_at 68808 1110046J04Rik5 - up both 393LN, 344 SQ 1110046J04 gene 0.045302 2.066197 0.00186 2.122106 B lymphoma Mo- MLV insertion region 1417493_at 12151 Bmi1 5 - up both 393LN, 344 SQ 1 0.000569 1.825197 4E-06 2.115722 1436861_at 16196 Il7 5 - up both 393LN, 344 SQ interleukin 7 0.002559 1.945207 0.11763 2.108789

serine (or cysteine) peptidase inhibitor, 1439790_at 20723 Serpinb9 5 - up both 393LN, 344 SQ clade B, member 9 0.002257 2.440557 0.21971 2.108465 RIKEN cDNA 1435695_a_at 68252 A030007L17Ri 5 - up both 393LN, 344 SQ A030007L17 gene 0.024727 2.004068 0.00301 2.10599 G protein-coupled 1426782_at 70693 Gpr125 5 - up both 393LN, 344 SQ receptor 125 0.02969 1.503733 0.00118 2.105917

formin homology 2 1435557_at 234686 Fhod1 5 - up both 393LN, 344 SQ domain containing 1 0.000847 1.729091 0.00033 2.104969

N-acetylglucosamine- 1-phosphate transferase, alpha 1435335_a_at 432486 Gnptab 5 - up both 393LN, 344 SQ and beta subunits 0.011616 1.862385 0.00078 2.087435 poly(rC) binding 1433658_x_at 59092 Pcbp4 5 - up both 393LN, 344 SQ protein 4 0.010834 1.57024 0.00068 2.079722 DAZ interacting 1436354_at 72507 Dzip1l 5 - up both 393LN, 344 SQ protein 1-like 0.015238 1.788042 0.00107 2.077259 nuclear receptor 1435233_at 17978 Ncoa2 5 - up both 393LN, 344 SQ coactivator 2 0.000359 1.639131 2E-05 2.076572

phosphatidylinositol 3-kinase, catalytic, 1429434_at 18706 Pik3ca 5 - up both 393LN, 344 SQ alpha polypeptide 0.032816 1.683817 0.00073 2.071504 ATPase, H+ transporting, lysosomal V1 subunit G1 /// similar to vacuolar H+ ATPase G1 /// similar to vacuolar 1450926_at 623391 // Atp6v1g1 /// LO5 - up both 393LN, 344 SQ H+ ATPase G1 0.13973 2.046596 0.00493 2.065933

1449913_at 22678 Zfp2 5 - up both 393LN, 344 SQ zinc finger protein 2 0.057903 1.716701 0.00571 2.064223

DNA 1419750_at 13434 Dnmt2 5 - up both 393LN, 344 SQ methyltransferase 2 0.050871 1.556661 0.00327 2.058168

protein tyrosine phosphatase, receptor type, N /// similar to Receptor- type tyrosine-protein phosphatase-like N precursor (R-PTP-N) 1416588_at 19275 /// Ptprn /// LOC665 - up both 393LN, 344 SQ (PTP IA-2) 0.036465 1.564833 0.00448 2.058095 1418067_at 12632 Cfl2 5 - up both 393LN, 344 SQ cofilin 2, muscle 0.008088 1.484428 0.00011 2.057239 RIKEN cDNA 1434613_at 69053 1810013L24Ri 5 - up both 393LN, 344 SQ 1810013L24 gene 0.047712 1.473628 7.2E-05 2.055516 structural maintenance of 1422909_at 67241 Smc6 5 - up both 393LN, 344 SQ chromosomes 6 0.009201 2.097729 0.01351 2.051617

1455481_at 15931 Ids 5 - up both 393LN, 344 SQ iduronate 2-sulfatase 0.004234 1.644583 0.00022 2.050358 RIKEN cDNA 1428897_at 77032 2610029I01Rik5 - up both 393LN, 344 SQ 2610029I01 gene 0.009501 1.662031 0.00163 2.045314

protein phosphatase 2C, magnesium dependent, catalytic 1438201_at 381511 Ppm2c 5 - up both 393LN, 344 SQ subunit 0.014598 1.835487 0.00061 2.044995

T-cell lymphoma breakpoint 1429901_at 432450 Tcba1 5 - up both 393LN, 344 SQ associated target 1 0.004488 2.76231 0.0014 2.044985 DEAD (Asp-Glu-Ala- Asp) box polypeptide 1428702_at 71986 Ddx28 5 - up both 393LN, 344 SQ 28 0.000438 2.419 0.00807 2.039883 RIKEN cDNA 1437261_at 72852 2900024O10R 5 - up both 393LN, 344 SQ 2900024O10 gene 0.0071 1.9062 0.0096 2.035791 G protein-coupled 1436459_at 240888 Gpr161 5 - up both 393LN, 344 SQ receptor 161 0.071213 1.751078 0.00601 2.033497 RIKEN cDNA 1435274_at 76857 4921517N04Ri5 - up both 393LN, 344 SQ 4921517N04 gene 0.000845 2.242296 0.00045 2.032178 1426049_a_at ------5 - up both 393LN, 344 SQ --- 0.000539 2.049979 0.00093 2.021525

progesterone receptor membrane 1452882_at 70804 Pgrmc2 5 - up both 393LN, 344 SQ component 2 0.000431 1.951525 0.00053 2.009347 spermatogenesis 1454656_at 219140 Spata13 5 - up both 393LN, 344 SQ associated 13 0.039191 1.431984 0.00268 2.007545 1442348_at ------5 - up both 393LN, 344 SQ --- 0.001895 1.58402 0.00025 2.005483 ubiquitin specific peptidase 9, X 1428194_at 22284 Usp9x 5 - up both 393LN, 344 SQ chromosome 0.009265 2.105425 0.01092 2.002051 RIKEN cDNA 1451313_a_at 216551 1110067D22Ri5 - up both 393LN, 344 SQ 1110067D22 gene 0.005427 1.416671 0.00012 2.001074 islet cell autoantigen 1431644_a_at 15893 Ica1 5 - up both 393LN, 344 SQ 1 0.03479 2.185106 0.00772 1.996866 RIKEN cDNA 1428914_at 69633 2310014D11Ri5 - up both 393LN, 344 SQ 2310014D11 gene 0.006415 1.674378 0.00206 1.995415 phosphatase and 1455728_at 19211 Pten 5 - up both 393LN, 344 SQ tensin homolog 0.001963 1.4641 8.6E-05 1.990646 transmembrane 4 superfamily member 1450958_at 17112 Tm4sf1 5 - up both 393LN, 344 SQ 1 0.000982 1.554073 2.4E-05 1.990026 cartilage associated 1448592_at 56693 Crtap 5 - up both 393LN, 344 SQ protein 0.004041 1.524856 0.00054 1.989997 Zinc finger protein 1460085_at 226442 Zfp281 5 - up both 393LN, 344 SQ 281 0.001797 1.632599 0.00988 1.989266 ubiquitin specific peptidase 9, X 1428193_at 22284 Usp9x 5 - up both 393LN, 344 SQ chromosome 0.000438 1.975202 0.00032 1.982367

glutathione S- transferase, mu 1 /// similar to Glutathione S- transferase Mu 1 (GST class-mu 1) (Glutathione S- transferase GT8.7) (pmGT10) (GST 1-1) /// similar to Glutathione S- transferase Mu 1 (GST class-mu 1) (Glutathione S- transferase GT8.7) 1425627_x_at 14862 /// Gstm1 /// LOC45 - up both 393LN, 344 SQ (pmGT10) (GST 1-1) 0.190307 1.714632 0.00309 1.975488 lysosomal acid 1423140_at 16889 Lip1 5 - up both 393LN, 344 SQ lipase 1 0.068897 1.915556 0.00551 1.974868

ring finger and SPRY 1424135_at 67610 Rspry1 5 - up both 393LN, 344 SQ domain containing 1 0.00206 1.739403 0.00035 1.973553 inhibitor of kappaB 1454690_at 16151 Ikbkg 5 - up both 393LN, 344 SQ kinase gamma 0.006753 1.540048 0.00074 1.971919

eukaryotic translation initiation 1434593_at 208691 Eif5a2 5 - up both 393LN, 344 SQ factor 5A2 0.015814 1.539061 0.0013 1.959805 MTERF domain 1455700_at 74238 Mterfd3 5 - up both 393LN, 344 SQ containing 3 0.010191 1.706276 8.2E-05 1.952275 RIKEN cDNA 1454980_at 319518 4930402E16Ri 5 - up both 393LN, 344 SQ 4930402E16 gene 3.22E-05 1.546777 0.00405 1.951163 dedicator of 1436405_at 238130 Dock4 5 - up both 393LN, 344 SQ cytokinesis 4 0.005848 1.595109 0.00066 1.94988 DNA segment, Chr 14, ERATO Doi 171, 1434582_at 238988 D14Ertd171e 5 - up both 393LN, 344 SQ expressed 0.007852 2.283444 0.11936 1.947129 malignant fibrous histiocytoma amplified sequence 1429005_at 52065 Mfhas1 5 - up both 393LN, 344 SQ 1 0.005099 1.440391 0.00161 1.946551

ubiquitin-conjugating 1429131_at 70620 Ube2v2 5 - up both 393LN, 344 SQ enzyme E2 variant 2 0.000188 3.600914 0.00396 1.944248 ubiquitin specific 1436891_at 14479 Usp15 5 - up both 393LN, 344 SQ peptidase 15 0.005074 2.243639 0.02519 1.940045 RIKEN cDNA 1435315_s_at 72904 2900034E22Ri 5 - up both 393LN, 344 SQ 2900034E22 gene 0.001362 2.209634 0.0008 1.93998 Unc-51 like kinase 2 1417847_at 29869 Ulk2 5 - up both 393LN, 344 SQ (C. elegans) 0.002022 1.429632 5.7E-05 1.938066 cleavage and polyadenylation 1428231_at 432508 Cpsf6 5 - up both 393LN, 344 SQ specific factor 6 6.3E-05 2.226177 0.0001 1.936787 mitogen activated protein kinase 1450973_s_at 26390 Mapkbp1 5 - up both 393LN, 344 SQ binding protein 1 0.003923 1.557279 0.00206 1.935442

1417969_at 76454 Fbxo31 5 - up both 393LN, 344 SQ F-box only protein 31 0.007706 1.739417 0.00665 1.931037 fumarylacetoacetate 1417220_at 14085 Fah 5 - up both 393LN, 344 SQ hydrolase 0.002008 2.235343 0.00049 1.917057 1447693_s_at 18007 Neo1 5 - up both 393LN, 344 SQ neogenin 0.005357 2.346821 0.00098 1.914866

1436411_at 268878 Atp13a5 5 - up both 393LN, 344 SQ ATPase type 13A5 0.001717 3.063307 0.03493 1.914567

1457571_at 24135 Zfp68 5 - up both 393LN, 344 SQ zinc finger protein 68 0.003266 1.986264 0.00286 1.914151 armadillo repeat 1434949_at 74125 Armc8 5 - up both 393LN, 344 SQ containing 8 0.002763 1.97763 0.02336 1.911871 telomeric repeat binding factor 2, 1419381_at 57321 Terf2ip 5 - up both 393LN, 344 SQ interacting protein 0.002443 2.07885 0.00095 1.909587 U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1, related 1421128_at 22184 U2af1-rs2 5 - up both 393LN, 344 SQ sequence 2 0.012597 1.754296 0.00545 1.909199

acid phosphatase 6, 1448445_at 66659 Acp6 5 - up both 393LN, 344 SQ lysophosphatidic 0.022981 1.71076 0.00284 1.905936

1426339_at 229949 Ak5 5 - up both 393LN, 344 SQ adenylate kinase 5 0.254912 1.50165 0.00718 1.902353 zinc finger protein 1455638_at 79233 Zfp319 5 - up both 393LN, 344 SQ 319 0.005702 1.885564 0.00833 1.898306 RIKEN cDNA 1429371_at 67607 2810426N06Ri5 - up both 393LN, 344 SQ 2810426N06 gene 0.082832 1.445053 0.00848 1.897029 cDNA sequence 1438349_at 381067 BC043476 5 - up both 393LN, 344 SQ BC043476 0.064452 1.39174 0.00569 1.895662 1423626_at 13518 Dst 5 - up both 393LN, 344 SQ dystonin 0.002797 1.717892 0.00129 1.890658 sphingosine-1- phosphate 1420821_at 81535 Sgpp1 5 - up both 393LN, 344 SQ phosphatase 1 0.001652 2.316165 0.016 1.885231 RIKEN cDNA 1451570_a_at 68099 6720467C03Ri5 - up both 393LN, 344 SQ 6720467C03 gene 0.006057 1.650779 0.00077 1.884784 polymerase (RNA) III (DNA directed) 1451364_at 69870 Polr3gl 5 - up both 393LN, 344 SQ polypeptide G like 0.00384 1.564298 0.01064 1.883177 Solute carrier family 7, member 6 1440303_at 66432 Slc7a6os 5 - up both 393LN, 344 SQ opposite strand 0.000471 2.180338 5.4E-05 1.880723 RIKEN cDNA 1424259_at 76483 2400010G15R 5 - up both 393LN, 344 SQ 2400010G15 gene 0.186452 1.445607 0.00937 1.879858 retinoblastoma 1425115_at 19647 Rbbp6 5 - up both 393LN, 344 SQ binding protein 6 0.001163 2.568384 0.01201 1.879163 matrix-remodelling 1452330_a_at 74761 Mxra8 5 - up both 393LN, 344 SQ associated 8 0.008486 1.961636 0.01966 1.87889 kelch-like 7 1428091_at 52323 Klhl7 5 - up both 393LN, 344 SQ (Drosophila) 0.028468 1.725987 0.00306 1.876451 homeodomain interacting protein 1426819_at 15259 Hipk3 5 - up both 393LN, 344 SQ kinase 3 0.040034 1.428136 0.00207 1.876432 Gene model 879, 1455919_at 380702 Gm879 5 - up both 393LN, 344 SQ (NCBI) 0.133617 1.405957 0.00878 1.871486

EPM2A (laforin) 1434105_at 77781 Epm2aip1 5 - up both 393LN, 344 SQ interacting protein 1 0.003114 1.589772 0.00029 1.87064 Atpase, class VI, 1455083_at 320940 Atp11c 5 - up both 393LN, 344 SQ type 11C 0.000103 2.133184 0.00048 1.870336 kelch-like 23 1435743_at 277396 Klhl23 5 - up both 393LN, 344 SQ (Drosophila) 0.000188 2.659534 0.10497 1.865257

Adult male corpus striatum cDNA, RIKEN full-length enriched library, clone:C030020B06 product:unclassifiabl e, full insert 1435818_at ------5 - up both 393LN, 344 SQ sequence 0.001187 2.43199 0.00495 1.864104 RIKEN cDNA 1451276_at 75089 E030041M21R5 - up both 393LN, 344 SQ E030041M21 gene 0.007641 1.55297 0.00017 1.861871

4- nitrophenylphosphat ase domain and non- neuronal SNAP25- like protein homolog 1456748_a_at 18082 Nipsnap1 5 - up both 393LN, 344 SQ 1 (C. elegans) 0.069079 1.693756 0.00175 1.858296

Mammary gland RCB-0527 Jyg- MC(B) cDNA, RIKEN full-length enriched library, clone:G930010E14 product:unclassifiabl e, full insert 1447471_at ------5 - up both 393LN, 344 SQ sequence 0.008384 1.528919 0.00373 1.857078 FYVE and coiled-coil 1427177_at 17281 Fyco1 5 - up both 393LN, 344 SQ domain containing 1 0.001218 1.546161 0.0004 1.851285 transmembrane 1426672_at 102566 Tmem16k 5 - up both 393LN, 344 SQ protein 16K 0.004567 1.858238 0.00372 1.850307 RIKEN cDNA 1439516_at 70434 2610201A13Ri 5 - up both 393LN, 344 SQ 2610201A13 gene 0.000645 2.665758 0.04561 1.847981

Translocase of outer mitochondrial membrane 20 1435187_at 67952 Tomm20 5 - up both 393LN, 344 SQ homolog (yeast) 0.0001 3.074127 0.00377 1.847202

DnaJ (Hsp40) homolog, subfamily 1417441_at 30045 Dnajc12 5 - up both 393LN, 344 SQ C, member 12 0.059226 1.627423 0.00014 1.841072

1426269_at 20955 Sybl1 5 - up both 393LN, 344 SQ synaptobrevin like 1 1.86E-05 1.937117 0.00055 1.837992 nudix (nucleoside diphosphate linked moiety X)-type motif 1428339_at 68219 Nudt21 5 - up both 393LN, 344 SQ 21 2.63E-05 2.007566 6.6E-05 1.837299 tripartite motif 1417029_a_at 80890 Trim2 5 - up both 393LN, 344 SQ protein 2 0.05347 1.725841 0.00652 1.829401 Sec11-like 3 (S. 1460698_a_at 66286 Sec11l3 5 - up both 393LN, 344 SQ cerevisiae) 0.051963 1.414123 0.00628 1.825021

erythrocyte protein 1426010_a_at 13823 Epb4.1l3 5 - up both 393LN, 344 SQ band 4.1-like 3 0.067777 1.344748 0.00447 1.818326 casein kinase 1, 1429383_at 70425 Csnk1g3 5 - up both 393LN, 344 SQ gamma 3 0.0018 1.397504 0.00015 1.818249 oxidative-stress 1426933_at 108737 Oxsr1 5 - up both 393LN, 344 SQ responsive 1 0.014933 1.392205 0.00168 1.81714 1456840_at ------5 - up both 393LN, 344 SQ --- 0.009485 1.758566 0.02733 1.816057 testis expressed 1452213_at 21763 Tex2 5 - up both 393LN, 344 SQ gene 2 0.002099 1.632913 0.00012 1.809721 RIKEN cDNA 1456294_at 76892 0610013E23Ri 5 - up both 393LN, 344 SQ 0610013E23 gene 0.007833 1.830997 0.00485 1.806599 1451848_a_at 12972 Cryz 5 - up both 393LN, 344 SQ crystallin, zeta 0.028188 1.405432 2.3E-05 1.803975 aspartate-beta- 1450058_at 65973 Asph 5 - up both 393LN, 344 SQ hydroxylase 0.037527 1.336974 0.00402 1.803889 thyroid hormone 1443952_at 21833 Thra 5 - up both 393LN, 344 SQ receptor alpha 0.024471 1.434674 0.00078 1.802074

RIKEN cDNA 9630055N22 gene /// similar to Feline leukemia virus subgroup C receptor- related protein 1 (Feline leukemia virus subgroup C 1434424_at 226844 // 9630055N22Ri5 - up both 393LN, 344 SQ receptor) (hFLVCR) 0.000452 1.82883 5.6E-05 1.802044 zinc finger, DHHC domain containing 1434397_at 320150 Zdhhc17 5 - up both 393LN, 344 SQ 17 0.000311 1.674694 0.0003 1.800634 Unc-51 like kinase 2 1417846_at 29869 Ulk2 5 - up both 393LN, 344 SQ (C. elegans) 0.008434 1.546421 0.00033 1.795808 1435445_at 72949 Ccnt2 5 - up both 393LN, 344 SQ cyclin T2 0.000672 1.783378 0.00205 1.794037

teashirt zinc finger 1427232_at 110796 Tshz1 5 - up both 393LN, 344 SQ family member 1 0.01193 1.472051 0.00767 1.794002 RIKEN cDNA 1426521_at 234678 D230025D16R 5 - up both 393LN, 344 SQ D230025D16 gene 0.024873 1.573454 0.00507 1.79386

influenza virus NS1A 1425718_a_at 117198 Ivns1abp 5 - up both 393LN, 344 SQ binding protein 0.006672 1.880746 0.01205 1.792183 synaptic nuclear 1427982_s_at 319565 Syne2 5 - up both 393LN, 344 SQ envelope 2 0.020325 1.749248 0.00517 1.791218 ubiquitin specific 1427990_at 77593 Usp45 5 - up both 393LN, 344 SQ petidase 45 0.007365 1.629976 0.00145 1.790628 RIKEN cDNA 1454126_at 68402 0710001A04Ri 5 - up both 393LN, 344 SQ 0710001A04 gene 0.155696 1.423925 0.00093 1.790127

malic enzyme 2, NAD(+)-dependent, 1426573_at 107029 Me2 5 - up both 393LN, 344 SQ mitochondrial 0.104419 1.544863 0.00675 1.788096 transmembrane 9 superfamily member 1428412_at 107358 Tm9sf3 5 - up both 393LN, 344 SQ 3 1.19E-05 1.988726 0.00019 1.785777 1447223_at ------5 - up both 393LN, 344 SQ Transcribed locus 0.000442 1.581427 0.0406 1.782616 dual-specificity tyrosine-(Y)- phosphorylation 1428637_at 69181 Dyrk2 5 - up both 393LN, 344 SQ regulated kinase 2 0.028599 1.429204 0.00168 1.779553 branched chain aminotransferase 2, 1425764_a_at 12036 Bcat2 5 - up both 393LN, 344 SQ mitochondrial 0.027476 1.546265 0.00803 1.778375 FUS interacting protein (serine- 1449121_at 14105 Fusip1 5 - up both 393LN, 344 SQ arginine rich) 1 0.007635 1.395865 0.00333 1.777875 CREBBP/EP300 1454931_at 386655 Cri2 5 - up both 393LN, 344 SQ inhibitory protein 2 0.165888 1.397955 0.00651 1.775375 praja1, RING-H2 1426448_at 18744 Pja1 5 - up both 393LN, 344 SQ motif containing 0.002504 2.102764 0.06214 1.77071

region containing RIKEN cDNA 2310056B04 gene; pre B-cell leukemia 1428647_at 676870 LOC676870 5 - up both 393LN, 344 SQ transcription factor 1 0.08777 1.364336 0.00247 1.769987 kelch-like 7 1452660_s_at 52323 Klhl7 5 - up both 393LN, 344 SQ (Drosophila) 0.006967 1.605577 0.00445 1.767309

zinc finger CCCH 1444402_at 244871 Zc3h12c 5 - up both 393LN, 344 SQ type containing 12C 0.031939 1.529285 0.00486 1.766004

trans-acting 1437508_at 20688 Sp4 5 - up both 393LN, 344 SQ transcription factor 4 0.007985 1.787647 0.00754 1.761441 1449550_at 17913 Myo1c 5 - up both 393LN, 344 SQ myosin IC 0.017406 1.345544 0.00794 1.759697 NACHT, leucine rich repeat and PYD 1437299_at 97895 Nalp4f 5 - up both 393LN, 344 SQ containing 4F 0.002497 1.711393 0.00343 1.759289 oxysterol binding 1437069_at 237542 Osbpl8 5 - up both 393LN, 344 SQ protein-like 8 0.104305 1.55634 0.00246 1.755872

influenza virus NS1A 1450084_s_at 117198 Ivns1abp 5 - up both 393LN, 344 SQ binding protein 0.007189 1.844854 0.00049 1.755608 zinc finger matrin 1449353_at 22401 Zmat3 5 - up both 393LN, 344 SQ type 3 0.000793 1.992218 0.03743 1.753342 RIKEN cDNA 1421316_at 66195 1110058A15Ri 5 - up both 393LN, 344 SQ 1110058A15 gene 0.009768 1.625841 0.14311 1.748756 CDNA sequence 1443050_at 238024 BC032265 5 - up both 393LN, 344 SQ BC032265 0.008665 1.709285 0.01377 1.747564 1422306_at 16820 Lcn3 5 - up both 393LN, 344 SQ lipocalin 3 0.195894 1.393548 0.00503 1.743951 synaptojanin 2 1417834_at 24071 Synj2bp 5 - up both 393LN, 344 SQ binding protein 0.022241 1.463372 0.00172 1.742851

solute carrier family 25 (mitochondrial carrier, Aralar), 1428440_at 78830 Slc25a12 5 - up both 393LN, 344 SQ member 12 0.003806 1.694153 0.00819 1.741771 MON1 homolog b 1428712_at 270096 Mon1b 5 - up both 393LN, 344 SQ (yeast) 0.010986 2.201655 0.00134 1.741062

poly(A) polymerase 1427241_at 216578 Papolg 5 - up both 393LN, 344 SQ gamma 0.003373 1.470823 0.00012 1.738059 1455465_at 55988 Snx12 5 - up both 393LN, 344 SQ Sorting nexin 12 0.005715 2.05172 0.0072 1.736574 glutathione S- 1416842_at 14866 Gstm5 5 - up both 393LN, 344 SQ transferase, mu 5 0.016832 1.599399 0.00199 1.734462 glutamine and serine 1427151_at 99003 Qser1 5 - up both 393LN, 344 SQ rich 1 0.014784 1.568074 0.00077 1.733352 WD repeat domain 1435051_at 72404 Wdr44 5 - up both 393LN, 344 SQ 44 0.008844 1.64606 0.00236 1.729709 zinc finger protein 1435664_at 69256 Zfp397 5 - up both 393LN, 344 SQ 397 0.004447 1.5068 0.00124 1.728952 cardiotrophin-like 1437270_a_at 56708 Clcf1 5 - up both 393LN, 344 SQ cytokine factor 1 0.19416 1.465294 0.00441 1.726115

protein phosphatase 1A, magnesium dependent, alpha 1425537_at 19042 Ppm1a 5 - up both 393LN, 344 SQ isoform 0.001654 2.397297 0.0016 1.724017 FAST kinase 1427342_at 320720 Fastkd1 5 - up both 393LN, 344 SQ domains 1 0.04149 1.403197 5E-05 1.72205 ubiquitin specific 1428592_s_at 74841 Usp38 5 - up both 393LN, 344 SQ peptidase 38 0.001181 2.591564 0.00452 1.713446 arginine/serine-rich 1448584_at 66880 Rsrc1 5 - up both 393LN, 344 SQ coiled-coil 1 0.000778 1.775744 0.00018 1.707124 LysM, putative peptidoglycan- binding, domain 1428626_at 70082 Lysmd2 5 - up both 393LN, 344 SQ containing 2 0.024212 1.935092 0.00561 1.707089 dihydrouridine synthase 2-like (SMM1, S. 1452687_at 66369 Dus2l 5 - up both 393LN, 344 SQ cerevisiae) 0.001773 2.435997 0.01386 1.705956 zinc binding alcohol dehydrogenase, 1451277_at 225791 Zadh2 5 - up both 393LN, 344 SQ domain containing 2 0.004216 1.444981 0.00204 1.703245

SRY-box containing 1450191_a_at 20668 Sox13 5 - up both 393LN, 344 SQ gene 13 0.007527 1.748222 0.00177 1.703068

1429000_at 213109 Phf3 5 - up both 393LN, 344 SQ PHD finger protein 3 0.021667 1.334961 0.00011 1.702698 1421861_at 65945 Clstn1 5 - up both 393LN, 344 SQ calsyntenin 1 0.031591 1.328968 0.00334 1.700721 1421141_a_at 108655 Foxp1 5 - up both 393LN, 344 SQ forkhead box P1 0.011201 1.482211 7.5E-05 1.699266

glycogen synthase 1434439_at 56637 Gsk3b 5 - up both 393LN, 344 SQ kinase 3 beta 0.002864 1.654564 0.01389 1.697792 RIKEN cDNA 1435926_at 98357 E030003F13Ri5 - up both 393LN, 344 SQ E030003F13 gene 0.003163 1.665647 0.0019 1.696934 zinc finger, X-linked, duplicated A /// similar to Zinc finger X-linked protein 1439077_at 668171 // Zxda /// LOC665 - up both 393LN, 344 SQ ZXDA 0.002882 1.996676 0.00216 1.695283 tripartite motif protein 33 /// RIKEN cDNA 8030451N04 1455189_at 320735 // Trim33 /// 80305 - up both 393LN, 344 SQ gene 0.001307 1.428376 8.5E-06 1.694082

chromatin modifying 1418817_at 67064 Chmp1b 5 - up both 393LN, 344 SQ protein 1B 0.022135 1.328981 4.5E-05 1.692743 1437903_at 16948 Lox 5 - up both 393LN, 344 SQ lysyl oxidase 0.061759 1.335934 0.0033 1.6917

solute carrier family 25 (mitochondrial carrier, Graves disease autoantigen), 1434996_at 73132 Slc25a16 5 - up both 393LN, 344 SQ member 16 0.003901 1.483367 0.00015 1.689578 1428618_at 67933 Hcfc2 5 - up both 393LN, 344 SQ host cell factor C2 0.069258 1.435457 0.00638 1.688983 protein inhibitor of 1455611_at 56469 Pias1 5 - up both 393LN, 344 SQ activated STAT 1 0.041514 1.4268 0.00542 1.688982

abhydrolase domain 1451326_at 76491 Abhd14b 5 - up both 393LN, 344 SQ containing 14b 0.031118 1.41644 0.00047 1.688538

hypothetical protein 1441139_at 328186 B330003H21 5 - up both 393LN, 344 SQ B330003H21 0.000516 1.532693 0.00033 1.687256 integrin alpha FG- GAP repeat 1435637_at 71927 Itfg1 5 - up both 393LN, 344 SQ containing 1 0.007487 2.089217 0.04068 1.682556 RIKEN cDNA 1428332_at 216505 1500004A08Ri 5 - up both 393LN, 344 SQ 1500004A08 gene 0.007538 1.718359 0.00314 1.682486 1434931_at 18007 Neo1 5 - up both 393LN, 344 SQ neogenin 0.000845 2.165943 0.00238 1.680863

expressed sequence 1455352_at 102683 AU023006 5 - up both 393LN, 344 SQ AU023006 0.019497 1.452308 0.00737 1.680429

1449414_at 24132 Zfp53 5 - up both 393LN, 344 SQ zinc finger protein 53 0.076845 1.434023 1E-05 1.680099 CDC14 cell division cycle 14 homolog B 1429418_at 218294 Cdc14b 5 - up both 393LN, 344 SQ (S. cerevisiae) 0.011046 1.676928 0.00154 1.678371

golgi associated PDZ and coiled-coil 1453221_at 94221 Gopc 5 - up both 393LN, 344 SQ motif containing 0.002757 1.568562 0.00108 1.677498 CCAAT/enhancer binding protein 1423233_at 12609 Cebpd 5 - up both 393LN, 344 SQ (C/EBP), delta 0.05025 1.339229 0.00796 1.677078 RIKEN cDNA 1430879_at 77315 C030008P14R 5 - up both 393LN, 344 SQ C030008P14 gene 0.008663 2.619748 0.04981 1.67513

Mus musculus, clone IMAGE:4219318, 1442003_at ------5 - up both 393LN, 344 SQ mRNA 0.007613 1.313331 0.00022 1.673637 plasma membrane 1448945_at 67801 Pllp 5 - up both 393LN, 344 SQ proteolipid 0.055058 1.426425 0.00405 1.673632 HECT, UBA and WWE domain 1424949_at 59026 Huwe1 5 - up both 393LN, 344 SQ containing 1 0.001287 1.571222 0.00054 1.673442 solute carrier family 19 (thiamine transporter), member 1441315_s_at 116914 Slc19a2 5 - up both 393LN, 344 SQ 2 0.043287 1.422541 0.00842 1.673373

solute carrier family 16 (monocarboxylic acid transporters), 1434592_at 72472 Slc16a10 5 - up both 393LN, 344 SQ member 10 0.000742 2.007744 0.00067 1.672255

PREDICTED: Mus musculus similar to Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing protein) (Single- strand binding protein) (hnRNP core protein A1) (HDP) (LOC628392), 1441765_at ------5 - up both 393LN, 344 SQ mRNA 0.012921 1.435999 0.00338 1.67037 serologically defined colon cancer antigen 1435020_at 66244 Sdccag1 5 - up both 393LN, 344 SQ 1 0.00237 1.838289 0.05858 1.669874 splicing factor 3b, 1418561_at 81898 Sf3b1 5 - up both 393LN, 344 SQ subunit 1 0.006666 2.172979 0.02592 1.668016

RalBP1 associated Eps domain 1440822_x_at 19707 Reps1 5 - up both 393LN, 344 SQ containing protein 0.01146 1.43651 0.00052 1.667629 zinc finger protein 1460620_at 233410 Zfp592 5 - up both 393LN, 344 SQ 592 0.028366 1.453459 0.00881 1.664326 1436550_at 71865 Fbxo30 5 - up both 393LN, 344 SQ F-box protein 30 0.009089 1.903832 0.01073 1.660895 Casitas B-lineage 1455082_at 208650 Cblb 5 - up both 393LN, 344 SQ lymphoma b 0.03077 1.638002 0.00748 1.660023 RIKEN cDNA 1458491_at 71640 4930422I07Rik5 - up both 393LN, 344 SQ 4930422I07 gene 0.003756 1.946492 0.01 1.654861 Ras homolog gene 1455902_x_at 23912 Rhof 5 - up both 393LN, 344 SQ family, member f 0.172931 1.382125 0.00658 1.654085 zinc finger protein 1459048_s_at 77264 Zfp142 5 - up both 393LN, 344 SQ 142 0.006755 1.515826 0.0015 1.65403 cell growth regulator with EF hand domain 1424528_at 68567 Cgref1 5 - up both 393LN, 344 SQ 1 0.015206 1.779378 0.00736 1.652449 acyl-Coenzyme A binding domain 1428236_at 74159 Acbd5 5 - up both 393LN, 344 SQ containing 5 0.211404 1.345467 0.00596 1.651989 guanine nucleotide binding protein, 1449144_at 14672 Gna11 5 - up both 393LN, 344 SQ alpha 11 0.021905 1.421472 0.0056 1.651208 methyl CpG binding 1438930_s_at 17257 Mecp2 5 - up both 393LN, 344 SQ protein 2 0.049296 1.35408 0.0014 1.649616 OTU domain 1434468_at 73945 Otud4 5 - up both 393LN, 344 SQ containing 4 0.006835 1.728288 8.3E-05 1.644711 RIKEN cDNA 1428978_at 72876 2900009J20Rik5 - up both 393LN, 344 SQ 2900009J20 gene 0.001808 1.613457 9.5E-05 1.643299 leucine zipper transcription factor- 1460200_s_at 93730 Lztfl1 5 - up both 393LN, 344 SQ like 1 0.115899 1.654295 0.0003 1.643146 RIKEN cDNA 1451434_s_at 237943 5430405G24R 5 - up both 393LN, 344 SQ 5430405G24 gene 0.042045 1.346078 0.00297 1.642493 PR domain 1432057_a_at 70779 Prdm5 5 - up both 393LN, 344 SQ containing 5 0.009217 2.092086 0.00957 1.642418

RAB9, member RAS 1448391_at 56382 Rab9 5 - up both 393LN, 344 SQ oncogene family 0.001291 1.49516 0.0039 1.63834

1426913_at 16987 Lss 5 - up both 393LN, 344 SQ lanosterol synthase 0.133987 1.358301 0.00471 1.636028

expressed sequence 1456267_at 102085 AI451606 5 - up both 393LN, 344 SQ AI451606 0.001449 1.697815 0.00062 1.635888 FERM, RhoGEF and pleckstrin domain 1435985_at 227377 Farp2 5 - up both 393LN, 344 SQ protein 2 0.040995 1.524806 0.001 1.632966

RIKEN cDNA 1440817_x_at 244216 G630024C07R5 - up both 393LN, 344 SQ G630024C07 gene 0.004252 1.88866 0.01263 1.631825 expressed sequence 1459496_at 96956 C77267 5 - up both 393LN, 344 SQ C77267 0.077698 1.308909 0.0078 1.630818

trinucleotide repeat 1434898_at 233833 Tnrc6a 5 - up both 393LN, 344 SQ containing 6a 0.005879 1.343198 0.00302 1.627915 RIKEN cDNA 1434817_s_at 75137 4930535B03Ri 5 - up both 393LN, 344 SQ 4930535B03 gene 0.008622 1.580677 0.11874 1.625004 1459522_s_at 27357 Gyg 5 - up both 393LN, 344 SQ glycogenin 5.22E-05 1.830433 0.00012 1.624112 synaptophysin-like 1422882_at 19027 Sypl 5 - up both 393LN, 344 SQ protein 0.003682 1.822526 0.04421 1.618073 1419922_s_at 226255 Atrnl1 5 - up both 393LN, 344 SQ attractin like 1 0.033062 1.398437 0.00236 1.615431

myocyte enhancer 1434487_at 17261 Mef2d 5 - up both 393LN, 344 SQ factor 2D 0.007914 1.31766 0.00019 1.614292 cDNA sequence 1455378_at 194237 BC057371 5 - up both 393LN, 344 SQ BC057371 0.003115 1.446144 6.8E-05 1.613891

DnaJ (Hsp40) homolog, subfamily 1417191_at 27362 Dnajb9 5 - up both 393LN, 344 SQ B, member 9 0.042039 1.389961 0.00228 1.611613 Tumor necrosis factor, alpha-induced 1457918_at 21928 Tnfaip2 5 - up both 393LN, 344 SQ protein 2 0.038317 1.346321 0.0044 1.610357 adiponectin receptor 1424312_at 72674 Adipor1 5 - up both 393LN, 344 SQ 1 0.003322 1.306655 0.00169 1.608935 cDNA sequence 1434075_at 233812 BC030336 5 - up both 393LN, 344 SQ BC030336 0.039447 1.532998 0.00427 1.608486 ADP-ribosylation 1433642_at 218639 Arl15 5 - up both 393LN, 344 SQ factor-like 15 0.00172 1.531638 0.00053 1.608369 cullin associated and neddylation 1435781_at 71902 Cand1 5 - up both 393LN, 344 SQ disassociated 1 0.002216 1.656222 0.00727 1.608275 myotubularin related 1434676_at 210376 Mtmr9 5 - up both 393LN, 344 SQ protein 9 0.072508 1.265879 0.00564 1.607468 UBX domain 1426484_at 67812 Ubxd2 5 - up both 393LN, 344 SQ containing 2 0.004835 1.879673 0.00616 1.607123 RAB4A, member RAS oncogene 1449048_s_at 19341 Rab4a 5 - up both 393LN, 344 SQ family 0.009396 1.754398 0.01073 1.606526 E1A binding protein 1447712_x_at 75560 Ep400 5 - up both 393LN, 344 SQ p400 0.00422 1.80498 0.05124 1.606204 Musashi homolog 2 1436818_a_at 76626 Msi2 5 - up both 393LN, 344 SQ (Drosophila) 0.028687 1.36858 0.00665 1.606106 coiled-coil domain 1455805_x_at 54638 Ccdc22 5 - up both 393LN, 344 SQ containing 22 0.001057 1.68593 0.00156 1.604513 pecanex homolog 1419047_at 54604 Pcnx 5 - up both 393LN, 344 SQ (Drosophila) 0.000936 1.872018 0.01529 1.600799 chemokine (C-X-C 1449925_at 12766 Cxcr3 5 - up both 393LN, 344 SQ motif) receptor 3 0.020894 1.263668 0.00514 1.600712

amidohydrolase 1434855_at 245847 Amdhd2 5 - up both 393LN, 344 SQ domain containing 2 0.008509 1.556525 0.01964 1.6007 X-ray repair complementing defective repair in Chinese hamster 1451968_at 22596 Xrcc5 5 - up both 393LN, 344 SQ cells 5 0.00694 1.841261 0.00796 1.599682 RIKEN cDNA 1440018_at 320261 A330043J11Ri 5 - up both 393LN, 344 SQ A330043J11 gene 0.414422 1.559361 0.00027 1.599641 1448429_at 27357 Gyg 5 - up both 393LN, 344 SQ glycogenin 0.000222 1.727378 0.00063 1.597018 transmembrane 1426628_at 234463 Tmem34 5 - up both 393LN, 344 SQ protein 34 0.006098 1.631501 0.04364 1.596763

expressed sequence 1440221_at 106846 AA408650 5 - up both 393LN, 344 SQ AA408650 0.002465 1.705352 0.00555 1.596282 1436400_at ------5 - up both 393LN, 344 SQ --- 0.006957 1.485712 0.00287 1.595191 structural maintenance of 1448829_at 67241 Smc6 5 - up both 393LN, 344 SQ chromosomes 6 4.68E-05 1.906997 0.00637 1.59418 similar to TGF beta- inducible nuclear protein 1 (L-name- related protein 42) 1423131_at 433230 LOC433230 5 - up both 393LN, 344 SQ (LNR42) 0.003575 1.518479 0.00824 1.591002 WD repeat and FYVE domain 1427456_at 72145 Wdfy3 5 - up both 393LN, 344 SQ containing 3 0.034103 1.581884 0.00268 1.587075 autocrine motility 1450102_a_at 23802 Amfr 5 - up both 393LN, 344 SQ factor receptor 0.006322 1.513139 0.00366 1.58703 RIKEN cDNA 1453078_at 74520 8430408J07Rik5 - up both 393LN, 344 SQ 8430408J07 gene 0.000252 2.278613 0.01189 1.582537 RIKEN cDNA 1435916_at 75684 2210410P13Ri 5 - up both 393LN, 344 SQ 2210410P13 gene 0.009276 1.404903 0.00829 1.582165

branched chain ketoacid dehydrogenase E1, 1427153_at 12040 Bckdhb 5 - up both 393LN, 344 SQ beta polypeptide 5.98E-05 2.351714 0.00297 1.581973

phosphatidylinositol 3-kinase, catalytic, 1460326_at 18706 Pik3ca 5 - up both 393LN, 344 SQ alpha polypeptide 0.018863 1.421721 0.00157 1.580746 1436389_at ------5 - up both 393LN, 344 SQ Transcribed locus 0.009746 1.419217 0.00453 1.580382

development and differentiation 1436181_at 211914 Ddef2 5 - up both 393LN, 344 SQ enhancing factor 2 0.02901 1.42326 0.00028 1.580262 RIKEN cDNA 1452874_at 72320 2510003E04Ri 5 - up both 393LN, 344 SQ 2510003E04 gene 0.00161 1.759954 3.4E-05 1.578587 DNA segment, Chr 9, ERATO Doi 402, 1455118_at 382117 D9Ertd402e 5 - up both 393LN, 344 SQ expressed 0.009593 1.924801 0.00786 1.577641 RIKEN cDNA 1428416_at 67306 3110050N22Ri5 - up both 393LN, 344 SQ 3110050N22 gene 0.00108 1.7354 0.03236 1.576973

expressed sequence 1434312_at 104877 AI788669 5 - up both 393LN, 344 SQ AI788669 0.003757 1.539236 0.03607 1.576839

acidic (leucine-rich) nuclear phosphoprotein 32 1451356_at 66471 Anp32e 5 - up both 393LN, 344 SQ family, member E 0.004 1.417227 0.00553 1.576523 1428917_at 67727 Stx17 5 - up both 393LN, 344 SQ syntaxin 17 0.001359 1.685193 0.0054 1.576072 dual-specificity tyrosine-(Y)- phosphorylation 1436918_at 69181 Dyrk2 5 - up both 393LN, 344 SQ regulated kinase 2 0.101196 1.351251 0.00964 1.5755

guanine nucleotide binding protein, 1455729_at 14682 Gnaq 5 - up both 393LN, 344 SQ alpha q polypeptide 0.002377 1.54595 0.00104 1.57533 1429430_at ------5 - up both 393LN, 344 SQ --- 0.006447 1.376764 0.00067 1.574492 WD repeat domain 1424786_s_at 54636 Wdr45 5 - up both 393LN, 344 SQ 45 0.019778 1.41521 0.00753 1.573716

expressed sequence 1442005_at 100467 AW987390 5 - up both 393LN, 344 SQ AW987390 0.059097 1.281578 0.00907 1.572904 acyl-Coenzyme A dehydrogenase 1454647_at 102632 Acad11 5 - up both 393LN, 344 SQ family, member 11 0.039398 1.428088 0.0029 1.571474 1428287_at 75717 Cul5 5 - up both 393LN, 344 SQ cullin 5 0.003873 1.412916 0.00181 1.570884 RAB11 family interacting protein 2 1455169_at 74998 Rab11fip2 5 - up both 393LN, 344 SQ (class I) 0.005645 1.560899 0.00846 1.570659 similar to Zinc finger X-linked protein 1460441_at 668166 LOC668166 5 - up both 393LN, 344 SQ ZXDB 0.000313 1.671157 3.3E-05 1.570075

N-acetylglucosamine- 1-phosphate transferase, alpha 1456620_at 432486 Gnptab 5 - up both 393LN, 344 SQ and beta subunits 0.003413 1.587114 0.00028 1.566589 melanoma antigen, 1450062_a_at 94275 Maged1 5 - up both 393LN, 344 SQ family D, 1 0.019663 1.664684 0.00633 1.566445

1420600_at 22018 Tpo 5 - up both 393LN, 344 SQ thyroid peroxidase 0.070808 1.252503 0.00772 1.565982 RIKEN cDNA 1435241_at 320487 D930036F22R 5 - up both 393LN, 344 SQ D930036F22 gene 0.018964 1.382971 0.00805 1.565907 hydroxysteroid dehydrogenase like 1454996_at 72552 Hsdl1 5 - up both 393LN, 344 SQ 1 3.47E-07 1.744675 6E-05 1.56483 1439050_at ------5 - up both 393LN, 344 SQ --- 0.002178 1.70952 0.00414 1.563016 tripartite motif- 1429494_at 66854 Trim35 5 - up both 393LN, 344 SQ containing 35 0.033958 1.457103 0.00194 1.561011

Tnf receptor 1416571_at 22032 Traf4 5 - up both 393LN, 344 SQ associated factor 4 0.00456 1.423467 0.00386 1.55806

retinoblastoma-like 2 /// similar to 1425981_a_at 19651 /// Rbl2 /// LOC63 5 - up both 393LN, 344 SQ retinoblastoma-like 2 0.040721 1.574904 0.00038 1.554779 nuclear factor of activated T-cells, cytoplasmic, calcineurin- 1419976_s_at 18021 Nfatc3 5 - up both 393LN, 344 SQ dependent 3 8.24E-05 1.559164 0.00032 1.553713 gene model 237, 1435923_at 211488 Gm237 5 - up both 393LN, 344 SQ (NCBI) 0.002174 1.549387 0.00257 1.553464 poly(rC) binding 1449055_x_at 59092 Pcbp4 5 - up both 393LN, 344 SQ protein 4 0.007884 1.569529 0.01914 1.553095 GTPase activating RANGAP domain- 1428594_at 56784 Garnl1 5 - up both 393LN, 344 SQ like 1 0.001474 1.506191 0.00268 1.552347

exportin, tRNA (nuclear export 1441682_s_at 73192 Xpot 5 - up both 393LN, 344 SQ receptor for tRNAs) 5.95E-05 1.466958 0.00015 1.552032 Vacuolar protein 1438223_at 245944 Vps54 5 - up both 393LN, 344 SQ sorting 54 (yeast) 0.019877 1.347089 0.00853 1.550912 TBC1 domain family, 1430133_at 245638 Tbc1d8b 5 - up both 393LN, 344 SQ member 8B 0.005604 1.57113 0.00068 1.549357 RIKEN cDNA 1452813_a_at 382030 5033428A16Ri 5 - up both 393LN, 344 SQ 5033428A16 gene 0.00696 1.507716 0.0036 1.54915 RalBP1 associated Eps domain 1416216_at 19707 Reps1 5 - up both 393LN, 344 SQ containing protein 0.002237 1.710954 0.00211 1.549104 TSR2, 20S rRNA accumulation, homolog (S. 1435170_at 69499 Tsr2 5 - up both 393LN, 344 SQ cerevisiae) 0.001094 1.762155 0.00164 1.548501 protein-O- mannosyltransferase 1433644_at 217734 Pomt2 5 - up both 393LN, 344 SQ 2 0.025337 1.543361 0.00497 1.547941 1434717_at 26554 Cul3 5 - up both 393LN, 344 SQ cullin 3 9.08E-05 1.728099 0.00096 1.547086 mannosidase 1, 1417111_at 17155 Man1a 5 - up both 393LN, 344 SQ alpha 0.095758 1.554698 0.00033 1.546321

mannosidase, alpha, 1434395_at 17156 Man1a2 5 - up both 393LN, 344 SQ class 1A, member 2 0.004781 1.553113 0.01872 1.545914 nudix (nucleoside diphosphate linked moiety X)-type motif 1437213_at 68219 Nudt21 5 - up both 393LN, 344 SQ 21 0.000179 1.841507 0.03683 1.545601 mitogen activated 1453104_at 26413 Mapk1 5 - up both 393LN, 344 SQ protein kinase 1 0.00456 1.462075 0.00055 1.544865 selenophosphate 1418325_at 20768 Sephs2 5 - up both 393LN, 344 SQ synthetase 2 0.077979 1.314558 0.00805 1.541913 nuclear receptor- binding SET-domain protein 1 /// adrenocortical 1420882_a_at 18193 /// Nsd1 /// Acd 5 - up both 393LN, 344 SQ dysplasia 0.003037 1.300032 0.00288 1.541026 GATA zinc finger domain containing 1437507_at 229542 Gatad2b 5 - up both 393LN, 344 SQ 2B 0.008373 1.347115 0.00053 1.540953 RIKEN cDNA 1450987_a_at 66358 2310004I24Rik5 - up both 393LN, 344 SQ 2310004I24 gene 0.000164 1.369572 0.00079 1.540469 methyl CpG binding 1460246_at 17257 Mecp2 5 - up both 393LN, 344 SQ protein 2 0.001045 1.368126 0.00042 1.538933

dolichyl-phosphate (UDP-N- acetylglucosamine) acetylglucosamineph osphotransferase 1 (GlcNAc-1-P 1448549_a_at 13478 Dpagt1 5 - up both 393LN, 344 SQ transferase) 0.074241 1.280951 0.0092 1.53773

dynein, cytoplasmic 1 light intermediate 1433925_at 234663 Dync1li2 5 - up both 393LN, 344 SQ chain 2 0.002902 1.444608 0.0004 1.537619 SEC63-like (S. 1424925_at 140740 Sec63 5 - up both 393LN, 344 SQ cerevisiae) 0.008466 1.495721 0.00436 1.534853 neural precursor cell expressed, developmentally down-regulted gene 1450431_a_at 17999 Nedd4 5 - up both 393LN, 344 SQ 4 0.061481 1.242509 0.00194 1.534513 1434888_a_at 17184 Matr3 5 - up both 393LN, 344 SQ matrin 3 0.005123 1.298546 0.00079 1.53409 1458273_at ------5 - up both 393LN, 344 SQ Transcribed locus 0.00292 1.91186 0.00813 1.531315 1437208_at 103080 39701 5 - up both 393LN, 344 SQ septin 10 0.084368 1.27131 0.00581 1.528924 1423724_at 52696 Zwint 5 - up both 393LN, 344 SQ ZW10 interactor 0.001766 1.541543 0.00544 1.527702

phosphatidylinositol 1420411_a_at 67073 Pi4k2b 5 - up both 393LN, 344 SQ 4-kinase type 2 beta 0.213469 1.327474 0.00903 1.52659 1417487_at 14283 Fosl1 5 - up both 393LN, 344 SQ fos-like antigen 1 0.00789 1.632611 0.05339 1.526178

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5 /// RIKEN cDNA 9230115A19 gene /// similar to SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1424205_at 545700 // Smarca5 /// 92 5 - up both 393LN, 344 SQ 5 0.000146 1.884299 0.00101 1.524386 GLI-Kruppel family 1455154_at 14634 Gli3 5 - up both 393LN, 344 SQ member GLI3 0.01217 1.568534 0.00992 1.524036 nuclear fragile X mental retardation protein interacting 1435632_at 68564 Nufip2 5 - up both 393LN, 344 SQ protein 2 0.000866 1.478576 0.00208 1.522755 1417861_at 51813 Ccnc 5 - up both 393LN, 344 SQ cyclin C 0.004648 1.467459 0.00136 1.522699 1421142_s_at 108655 Foxp1 5 - up both 393LN, 344 SQ forkhead box P1 0.044536 1.337158 0.00302 1.520182

0 day neonate head cDNA, RIKEN full- length enriched library, clone:4833431M13 product:unclassifiabl e, full insert 1455406_at ------5 - up both 393LN, 344 SQ sequence 0.000134 1.669192 0.00119 1.519439 nuclear receptor 1435234_at 17978 Ncoa2 5 - up both 393LN, 344 SQ coactivator 2 0.003259 1.493206 0.00312 1.518477 fibroblast growth 1435747_at 14169 Fgf14 5 - up both 393LN, 344 SQ factor 14 0.007842 2.088685 0.14192 1.51729

acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3- oxoacyl-Coenzyme 1428146_s_at 52538 Acaa2 5 - up both 393LN, 344 SQ A thiolase) 0.000257 1.517396 0.01369 1.516409 nuclear DNA binding 1448505_at 57316 C1d 5 - up both 393LN, 344 SQ protein 0.068915 1.236372 0.00907 1.516368 DCUN1D1 DCN1, defective in cullin neddylation 1, domain containing 1 1455053_a_at 114893 Dcun1d1 5 - up both 393LN, 344 SQ (S. cerevisiae) 0.07442 1.244947 0.00035 1.514376 exportin, tRNA (nuclear export 1428772_at 73192 Xpot 5 - up both 393LN, 344 SQ receptor for tRNAs) 2.44E-05 1.443894 9.3E-05 1.513849

expressed sequence 1436641_at 107166 AI415730 5 - up both 393LN, 344 SQ AI415730 0.2137 1.268434 0.00685 1.512539 RIKEN cDNA 1433852_at 77480 C330002I19Rik5 - up both 393LN, 344 SQ C330002I19 gene 0.017225 1.337726 7.6E-05 1.511851 leucine-rich repeat 1431394_a_at 66725 Lrrk2 5 - up both 393LN, 344 SQ kinase 2 0.131422 1.31559 0.00259 1.509092

eukaryotic translation initiation 1437071_at 66235 Eif1ay 5 - up both 393LN, 344 SQ factor 1A, Y-linked 0.002139 1.624725 0.01077 1.508341 zinc finger protein 1437009_a_at 67845 Zfp364 5 - up both 393LN, 344 SQ 364 0.022232 1.36714 0.00343 1.508174 thyroid hormone receptor interactor 1423899_at 14897 Trip12 5 - up both 393LN, 344 SQ 12 0.000372 1.60284 0.00697 1.507919 synaptophysin-like 1435081_at 19027 Sypl 5 - up both 393LN, 344 SQ protein 0.001833 1.864734 0.01129 1.506872

zinc finger CCCH 1437111_at 244871 Zc3h12c 5 - up both 393LN, 344 SQ type containing 12C 0.004197 1.352322 2.4E-05 1.505744 RIKEN cDNA 1435668_at 67544 4932442K08Ri 5 - up both 393LN, 344 SQ 4932442K08 gene 0.098054 1.258138 0.00095 1.505293

3-hydroxyisobutyryl- Coenzyme A 1451512_s_at 227095 Hibch 5 - up both 393LN, 344 SQ hydrolase 0.000445 2.101913 0.07788 1.504907

dynein, cytoplasmic 1 light intermediate 1433926_at 234663 Dync1li2 5 - up both 393LN, 344 SQ chain 2 0.018296 1.260723 0.00369 1.504904 membrane protein, 1450919_at 17524 Mpp1 5 - up both 393LN, 344 SQ palmitoylated 6.61E-05 1.974999 0.00097 1.504821 CREBBP/EP300 1448406_at 58521 Cri1 5 - up both 393LN, 344 SQ inhibitory protein 1 0.007283 1.990698 0.09413 1.502749 guanine nucleotide binding protein, 1434254_at 14672 Gna11 5 - up both 393LN, 344 SQ alpha 11 0.001911 1.253326 5.2E-05 1.500524

arginine-tRNA- 1435173_at 11907 Ate1 5 - up both 393LN, 344 SQ protein transferase 1 0.005231 1.545737 0.00014 1.50042 1421163_a_at 18027 Nfia 5 - up both 393LN, 344 SQ nuclear factor I/A 0.001091 1.520501 0.20117 1.499959 DEP domain 1424303_at 211896 Depdc7 5 - up both 393LN, 344 SQ containing 7 0.003608 1.676943 0.02038 1.499889 Alpha thalassemia/mental retardation syndrome X-linked 1438750_at 22589 Atrx 5 - up both 393LN, 344 SQ homolog (human) 0.003329 2.019448 0.03785 1.494966

fumarylacetoacetate hydrolase domain 1419547_at 68636 Fahd1 5 - up both 393LN, 344 SQ containing 1 0.007927 1.673699 0.02409 1.4848 RIKEN cDNA 1439671_at 74969 4930466K18Ri 5 - up both 393LN, 344 SQ 4930466K18 gene 0.007719 1.549307 0.02234 1.482263 structural maintenance of 1417736_at 67241 Smc6 5 - up both 393LN, 344 SQ chromosomes 6 0.00642 1.61065 0.04082 1.479609 monoamine oxidase 1442676_at 17161 Maoa 5 - up both 393LN, 344 SQ A 0.007263 1.695586 0.01242 1.479162 RIKEN cDNA 1443633_at 73516 1700086O06R 5 - up both 393LN, 344 SQ 1700086O06 gene 0.0035 1.737351 0.22508 1.47872 CDNA clone 1449655_a_at ------5 - up both 393LN, 344 SQ IMAGE:5690974 0.00049 1.623086 0.00318 1.478059

Rho GTPase 1450896_at 11855 Arhgap5 5 - up both 393LN, 344 SQ activating protein 5 0.009463 1.572981 0.0633 1.475548 methionine 1436531_at 56307 Metap2 5 - up both 393LN, 344 SQ aminopeptidase 2 0.001036 1.604405 0.0089 1.472454

SEC14 and spectrin 1455549_at 228071 Sestd1 5 - up both 393LN, 344 SQ domains 1 0.000104 1.834016 0.0002 1.458808 RIKEN cDNA 1460455_at 68795 1110059H15Ri5 - up both 393LN, 344 SQ 1110059H15 gene 0.007132 1.708213 0.00612 1.458713 vacuolar protein 1417510_at 116733 Vps4a 5 - up both 393LN, 344 SQ sorting 4a (yeast) 0.000523 1.679154 0.01371 1.45582

heterogeneous nuclear 1452774_at 229279 Hnrpa3 5 - up both 393LN, 344 SQ ribonucleoprotein A3 0.001255 2.116456 0.01592 1.452675 ADP-ribosylation 1417331_a_at 56297 Arl6 5 - up both 393LN, 344 SQ factor-like 6 0.001101 2.01148 0.00855 1.452037

expressed sequence 1436185_at 230249 AI314180 5 - up both 393LN, 344 SQ AI314180 0.00421 1.682188 0.08433 1.450831 sphingosine-1- phosphate 1420822_s_at 81535 Sgpp1 5 - up both 393LN, 344 SQ phosphatase 1 0.000731 1.843806 0.03855 1.450332

expressed sequence 1433903_at 328099 AU021838 5 - up both 393LN, 344 SQ AU021838 7.96E-05 1.867905 0.00024 1.44703

guanine nucleotide binding protein, 1428940_at 14682 Gnaq 5 - up both 393LN, 344 SQ alpha q polypeptide 7.46E-06 1.559672 0.00097 1.443061

fragile X mental retardation 1423369_at 14265 Fmr1 5 - up both 393LN, 344 SQ syndrome 1 homolog 6.11E-05 1.543154 0.00039 1.442603 hypothetical 1439641_at 553090 LOC553090 5 - up both 393LN, 344 SQ LOC553090 0.003988 1.586599 0.03964 1.441104 RIKEN cDNA 1433537_at 67403 4833408C14Ri5 - up both 393LN, 344 SQ 4833408C14 gene 0.001698 1.503505 0.00661 1.439802

dishevelled associated activator 1455244_at 208846 Daam1 5 - up both 393LN, 344 SQ of morphogenesis 1 0.004001 1.578399 0.04549 1.435222 1451541_at 66821 Bcs1l 5 - up both 393LN, 344 SQ BCS1-like (yeast) 0.008368 1.552969 0.0138 1.435107 transcription elongation factor B 1436226_at 67923 Tceb1 5 - up both 393LN, 344 SQ (SIII), polypeptide 1 0.002778 1.759971 0.03031 1.434529

RIKEN cDNA 0610008C08 gene /// hypothetical LOC621156 /// hypothetical protein 1452800_a_at 621156 // 0610008C08Ri5 - up both 393LN, 344 SQ LOC631337 2.61E-05 1.851791 0.00452 1.433516 RIKEN cDNA 1429910_at 70634 5730499H23Ri5 - up both 393LN, 344 SQ 5730499H23 gene 0.00072 1.607666 0.00619 1.433321

cytochrome P450, family 20, subfamily 1443782_x_at 77951 Cyp20a1 5 - up both 393LN, 344 SQ A, polypeptide 1 0.006015 1.654112 0.02742 1.427784

solute carrier family 9 (sodium/hydrogen exchanger), isoform 1435008_at 236794 Slc9a6 5 - up both 393LN, 344 SQ 6 0.000175 1.78494 0.00065 1.42679

1423390_at 20437 Siah1a 5 - up both 393LN, 344 SQ seven in absentia 1A 0.006247 1.59838 0.03613 1.424746

RIKEN cDNA 1444018_at 320462 B930098A02R 5 - up both 393LN, 344 SQ B930098A02 gene 0.005306 1.578767 0.00233 1.422996 RIKEN cDNA 1700047I17 gene /// similar to signal recognition particle 1460466_at 665155 // 1700047I17Rik5 - up both 393LN, 344 SQ 54 0.004979 1.779292 0.06342 1.422368

O-linked N- acetylglucosamine (GlcNAc) transferase (UDP-N- acetylglucosamine:p olypeptide-N- acetylglucosaminyl 1460631_at 108155 Ogt 5 - up both 393LN, 344 SQ transferase) 0.000794 1.843727 0.01179 1.422318 sphingomyelin phosphodiesterase 1416999_at 20598 Smpd2 5 - up both 393LN, 344 SQ 2, neutral 6.2E-05 1.933502 0.01971 1.41876 tripeptidyl peptidase 1421893_a_at 22019 Tpp2 5 - up both 393LN, 344 SQ II 0.001659 1.750506 0.02911 1.417327 kelch domain 1435086_s_at 69554 Klhdc2 5 - up both 393LN, 344 SQ containing 2 0.008186 1.672697 0.04693 1.415921

v-raf murine sarcoma 3611 viral 1426602_at 11836 Araf 5 - up both 393LN, 344 SQ oncogene homolog 0.003339 1.61857 0.01393 1.415477 1450690_at ------5 - up both 393LN, 344 SQ --- 0.002408 1.533356 0.00374 1.415433 RIKEN cDNA 1428498_at 72486 2610206B13Ri 5 - up both 393LN, 344 SQ 2610206B13 gene 0.004387 1.543111 0.00508 1.41514 zinc finger, AN1-type 1418408_at 66361 Zfand1 5 - up both 393LN, 344 SQ domain 1 0.00174 1.682122 0.05474 1.407693 coenzyme Q10 1438153_x_at 210582 Coq10a 5 - up both 393LN, 344 SQ homolog A (yeast) 0.006755 1.521333 0.00159 1.403337 ubiquitin specific 1455842_x_at 14479 Usp15 5 - up both 393LN, 344 SQ peptidase 15 0.008949 1.812281 0.21151 1.403126 RAB3A interacting 1436103_at 216363 Rab3ip 5 - up both 393LN, 344 SQ protein 0.002576 1.694871 0.02465 1.399386 WD repeat domain 1455278_at 207615 Wdr37 5 - up both 393LN, 344 SQ 37 0.003897 1.51402 0.04788 1.393211 cDNA sequence 1424290_at 209212 BC010311 5 - up both 393LN, 344 SQ BC010311 0.004767 1.518088 0.00706 1.391613 acyl-Coenzyme A binding domain 1452601_a_at 72482 Acbd6 5 - up both 393LN, 344 SQ containing 6 0.002793 1.770498 0.00666 1.38793 jumonji, AT rich interactive domain 1444157_a_at 20591 Jarid1c 5 - up both 393LN, 344 SQ 1C (Rbp2 like) 0.005171 1.513921 0.00231 1.386983 vacuolar protein sorting 26 homolog 1420495_a_at 30930 Vps26a 5 - up both 393LN, 344 SQ A (yeast) 0.000272 1.542572 0.0086 1.385479 1448223_at 26383 Fto 5 - up both 393LN, 344 SQ fatso 0.001393 1.6133 0.0001 1.380657 Dicer1, Dcr-1 homolog 1460571_at 192119 Dicer1 5 - up both 393LN, 344 SQ (Drosophila) 0.003771 1.644527 0.01386 1.378306 1436777_at ------5 - up both 393LN, 344 SQ --- 0.001637 1.879762 0.01701 1.375464 RIKEN cDNA 1456023_at 244721 2210010B09Ri 5 - up both 393LN, 344 SQ 2210010B09 gene 0.003341 1.627903 0.00685 1.374028 tryptophan rich basic 1460446_at 71446 Wrb 5 - up both 393LN, 344 SQ protein 0.001981 1.614843 0.00529 1.365021 Serpine1 mRNA 1418563_at 66870 Serbp1 5 - up both 393LN, 344 SQ binding protein 1 0.001114 1.799162 0.01219 1.364879 retinoblastoma 1425114_at 19647 Rbbp6 5 - up both 393LN, 344 SQ binding protein 6 0.003623 1.587595 0.00994 1.361452 high mobility group 1416155_at 15354 Hmgb3 5 - up both 393LN, 344 SQ box 3 0.003254 1.619939 0.01727 1.3614 isocitrate dehydrogenase 3 1416788_a_at 15929 Idh3g 5 - up both 393LN, 344 SQ (NAD+), gamma 0.007713 1.537694 0.02512 1.360932 cylindromatosis (turban tumor 1429201_at 74256 Cyld 5 - up both 393LN, 344 SQ syndrome) 0.001427 1.517891 0.00297 1.358704 ADP-ribosylation factor-like 2 binding 1417112_at 107566 Arl2bp 5 - up both 393LN, 344 SQ protein 0.000401 1.773418 0.00573 1.355812 RIKEN cDNA 1434550_at 218734 3830406C13Ri5 - up both 393LN, 344 SQ 3830406C13 gene 0.001501 1.750149 0.06756 1.353226

PRP39 pre-mRNA processing factor 39 1428172_at 328110 Prpf39 5 - up both 393LN, 344 SQ homolog (yeast) 0.005929 1.623017 0.09224 1.348411 phosphorylase 1434511_at 102093 Phkb 5 - up both 393LN, 344 SQ kinase beta 0.00157 1.751304 0.00035 1.345375 RAP2C, member of RAS oncogene 1460430_at 72065 Rap2c 5 - up both 393LN, 344 SQ family 0.001801 1.517048 0.0019 1.344712 RIKEN cDNA 1430407_at 73161 3110035C09Ri5 - up both 393LN, 344 SQ 3110035C09 gene 0.002371 1.739565 0.02094 1.341392 protein phosphatase 1F (PP2C domain 1454934_at 68606 Ppm1f 5 - up both 393LN, 344 SQ containing) 0.000755 1.691248 0.00498 1.341276

protein arginine N- 1425059_at 99890 Prmt6 5 - up both 393LN, 344 SQ methyltransferase 6 0.000941 1.696709 0.07527 1.325264

heterogeneous nuclear 1452712_at 229279 Hnrpa3 5 - up both 393LN, 344 SQ ribonucleoprotein A3 0.000641 1.515424 0.03547 1.325209

AT hook containing 1451459_at 226747 Ahctf1 5 - up both 393LN, 344 SQ transcription factor 1 0.000557 1.617917 0.00736 1.324703 CREBBP/EP300 1416614_at 58521 Cri1 5 - up both 393LN, 344 SQ inhibitory protein 1 0.003887 1.590982 0.07629 1.32075 RIKEN cDNA 1428982_at 320817 D530031C13R 5 - up both 393LN, 344 SQ D530031C13 gene 0.00995 1.520978 0.03693 1.320291

WD repeat domain, phosphoinositide 1456624_at 52639 Wipi1 5 - up both 393LN, 344 SQ interacting 1 0.002501 1.626203 0.00947 1.319528 NMDA receptor- 1435139_at 74838 Narg1 5 - up both 393LN, 344 SQ regulated gene 1 0.001985 1.656229 0.02789 1.316445 RIKEN cDNA 1428745_a_at 69487 2310003L22Ri 5 - up both 393LN, 344 SQ 2310003L22 gene 0.000679 1.669837 0.09446 1.315689 insulin degrading 1435140_at 15925 Ide 5 - up both 393LN, 344 SQ enzyme 0.001418 1.568229 0.01898 1.312268 ELMO domain 1433730_at 244548 Elmod2 5 - up both 393LN, 344 SQ containing 2 0.003019 1.732278 0.00225 1.310446 integrin-linked kinase-associated serine/threonine 1452506_a_at 67444 Ilkap 5 - up both 393LN, 344 SQ phosphatase 2C 0.004627 1.526941 0.02128 1.30847

ATP-binding cassette, sub-family B (MDR/TAP), 1435006_s_at 11306 Abcb7 5 - up both 393LN, 344 SQ member 7 0.000596 1.515 0.00964 1.306239 FIP1 like 1 (S. 1428280_at 66899 Fip1l1 5 - up both 393LN, 344 SQ cerevisiae) 0.00095 1.632505 0.01646 1.305321

ubiquitin-conjugating 1435384_at 93765 Ube2n 5 - up both 393LN, 344 SQ enzyme E2N 0.001986 1.515505 0.00915 1.297339 RIKEN cDNA 1419577_at 103199 A530089I17Rik5 - up both 393LN, 344 SQ A530089I17 gene 0.006516 1.533483 0.00375 1.292317

1417501_at 50762 Fbxo6b 5 - up both 393LN, 344 SQ F-box only protein 6b 0.003833 1.524376 0.12974 1.283185 ubiquitin specific peptidase 9, X 1420922_at 22284 Usp9x 5 - up both 393LN, 344 SQ chromosome 0.000638 1.554165 0.02497 1.279776 cDNA sequence 1435228_at 236848 BC023829 5 - up both 393LN, 344 SQ BC023829 0.00082 1.593537 0.02682 1.271656

UDP-glucose 1426461_at 216558 Ugp2 5 - up both 393LN, 344 SQ pyrophosphorylase 2 0.00432 1.513983 0.11052 1.267465 RIKEN cDNA 1436052_at 70373 1700020O03R 5 - up both 393LN, 344 SQ 1700020O03 gene 0.002513 1.586291 0.0034 1.258558 RIKEN cDNA 1428421_a_at 67201 2700085E05Ri 5 - up both 393LN, 344 SQ 2700085E05 gene 0.000407 1.506216 0.03362 1.257814 cleavage and polyadenylation factor subunit homolog (S. 1427160_at 74737 Pcf11 5 - up both 393LN, 344 SQ cerevisiae) 0.005746 1.531165 0.09163 1.254717 1436177_at ------5 - up both 393LN, 344 SQ Transcribed locus 0.008033 1.535882 0.00103 1.25376 RAD51-like 1 (S. 1439301_at 19363 Rad51l1 5 - up both 393LN, 344 SQ cerevisiae) 0.007565 1.549516 0.08296 1.244828 DNA segment, Chr 1, ERATO Doi 448, 1455723_at 52318 D1Ertd448e 5 - up both 393LN, 344 SQ expressed 0.003977 1.500987 0.05532 1.242112

patatin-like phospholipase 1417768_at 67452 Pnpla8 5 - up both 393LN, 344 SQ domain containing 8 0.00187 1.521158 0.00228 1.23495 tripartite motif- 1436806_at 67525 Trim62 6 - down both 393LN, 344 SQ containing 62 0.005394 0.419704 0.38363 0.851698

X-linked lymphocyte- 1430226_at 72891 Xlr4c 6 - down both 393LN, 344 SQ regulated 4C 0.008282 0.278078 0.35814 0.842355 sperm associated 1441708_at 66722 Spag16 6 - down both 393LN, 344 SQ antigen 16 0.005244 0.656609 0.29079 0.836209 RIKEN cDNA 1431615_at 218102 4930558J22Rik6 - down both 393LN, 344 SQ 4930558J22 gene 0.00108 0.645569 0.07075 0.802341

1457298_at ------6 - down both 393LN, 344 SQ --- 0.002746 0.641183 0.13411 0.799575

visual system homeobox 1 1450487_at 114889 Vsx1 6 - down both 393LN, 344 SQ homolog (zebrafish) 0.000781 0.639537 0.07267 0.794465

DnaJ (Hsp40) homolog, subfamily 1436180_at 13002 Dnajc5 6 - down both 393LN, 344 SQ C, member 5 0.002561 0.657777 0.01019 0.787146

vitamin K epoxide reductase complex, 1429092_at 69568 Vkorc1l1 6 - down both 393LN, 344 SQ subunit 1-like 1 0.001048 0.65612 0.02232 0.783817 Calmodulin binding transcription 1452229_at 216874 Camta2 6 - down both 393LN, 344 SQ activator 2 0.001461 0.556726 0.12163 0.76356 ankyrin repeat 1434630_at 105522 Ankrd28 6 - down both 393LN, 344 SQ domain 28 0.001515 0.617454 0.04843 0.762945 zinc finger with KRAB and SCAN 1429152_at 74570 Zkscan1 6 - down both 393LN, 344 SQ domains 1 0.000771 0.632582 0.02223 0.762818

membrane-spanning 4-domains, subfamily A, member 1443264_at 14126 Ms4a2 6 - down both 393LN, 344 SQ 2 0.00174 0.646367 0.09634 0.762613 RIKEN cDNA 1459327_at 66743 4931406I20Rik6 - down both 393LN, 344 SQ 4931406I20 gene 0.008555 0.563172 0.16251 0.762072 similar to gonadotropin inducible ovarian transcription factor 1 /// similar to zinc finger protein 709 /// similar to gonadotropin inducible ovarian transcription factor 1 /// similar to gonadotropin inducible ovarian 1436462_at 626832 // LOC626832 /// 6 - down both 393LN, 344 SQ transcription factor 1 0.001897 0.623474 0.08476 0.759871 wings apart-like homolog 1434835_at 218914 Wapal 6 - down both 393LN, 344 SQ (Drosophila) 0.001396 0.650503 0.00646 0.759605 expressed sequence 1447197_at 97664 C86544 6 - down both 393LN, 344 SQ C86544 0.005499 0.610828 0.12278 0.738609 leucine rich repeat 1433505_a_at 231549 Lrrc8d 6 - down both 393LN, 344 SQ containing 8D 0.009877 0.636085 0.00826 0.729971 RIKEN cDNA 1451477_at 70005 1700029I01Rik6 - down both 393LN, 344 SQ 1700029I01 gene 0.001217 0.559411 0.02386 0.729284 RIKEN cDNA 1453639_s_at 68394 0610037D15Ri6 - down both 393LN, 344 SQ 0610037D15 gene 0.005789 0.592057 0.04267 0.726511 growth factor receptor bound 1417673_at 50915 Grb14 6 - down both 393LN, 344 SQ protein 14 0.000957 0.666519 0.00078 0.71488

FBJ osteosarcoma 1423100_at 14281 Fos 6 - down both 393LN, 344 SQ oncogene 0.003097 0.465312 0.18519 0.713366 ataxia, cerebellar, Cayman type 1454972_at 16467 Atcay 6 - down both 393LN, 344 SQ homolog (human) 0.001826 0.330666 0.30607 0.71316

RIKEN cDNA 1441464_at 319627 A630035D09R 6 - down both 393LN, 344 SQ A630035D09 gene 0.002947 0.640547 0.02548 0.709725

RNA (guanine-9-) methyltransferase 1435035_at 108943 Rg9mtd2 6 - down both 393LN, 344 SQ domain containing 2 0.009095 0.650142 0.01828 0.709493

1415993_at 20775 Sqle 6 - down both 393LN, 344 SQ squalene epoxidase 0.000596 0.618887 0.00583 0.706433

transcription factor 7, 1433471_at 21414 Tcf7 6 - down both 393LN, 344 SQ T-cell specific 0.001589 0.575782 0.06223 0.705683

1422054_a_at 20482 Skil 6 - down both 393LN, 344 SQ SKI-like 1.06E-05 0.547949 0.00326 0.701253 patched homolog 2 /// similar to Protein patched homolog 2 1457256_x_at 19207 /// Ptch2 /// LOC6 6 - down both 393LN, 344 SQ (PTC2) 0.008522 0.666264 0.06529 0.701214 solute carrier family 16 (monocarboxylic acid transporters), 1449005_at 80879 Slc16a3 6 - down both 393LN, 344 SQ member 3 0.002185 0.583385 0.01199 0.696456

human papillomavirus 18 E5 central sequence 1422424_at 15456 Hpvc2 6 - down both 393LN, 344 SQ motif gene 2 0.003937 0.524083 0.08093 0.694712

1455435_s_at ------6 - down both 393LN, 344 SQ --- 0.001228 0.632785 0.00327 0.689612 metastasis 1443729_at 211401 Mtss1 6 - down both 393LN, 344 SQ suppressor 1 0.005186 0.538638 0.05171 0.688168

BCL2-like 11 1459794_at 12125 Bcl2l11 6 - down both 393LN, 344 SQ (apoptosis facilitator) 0.005648 0.484455 0.06639 0.685339 cDNA sequence 1429269_at 73072 BC068157 6 - down both 393LN, 344 SQ BC068157 0.003753 0.487113 0.02275 0.680178

RNA (guanine-9-) methyltransferase 1447781_s_at 108943 Rg9mtd2 6 - down both 393LN, 344 SQ domain containing 2 0.004351 0.627732 0.00969 0.679195 gene model 489, 1457707_at 244049 Gm489 6 - down both 393LN, 344 SQ (NCBI) 0.000772 0.600414 0.00495 0.675755

T-cell lymphoma breakpoint 1453329_s_at 432450 Tcba1 6 - down both 393LN, 344 SQ associated target 1 0.001212 0.483104 0.09464 0.673855 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 1420696_at 20348 Sema3c 6 - down both 393LN, 344 SQ (semaphorin) 3C 0.005393 0.489236 0.05856 0.672283

purine rich element 1419641_at 19291 Purb 6 - down both 393LN, 344 SQ binding protein B 0.000921 0.651703 0.00015 0.670603 RIKEN cDNA 1431046_at 76787 2410127E16Ri 6 - down both 393LN, 344 SQ 2410127E16 gene 0.001678 0.646119 0.01598 0.669041

protein kinase, AMP- activated, beta 1 non- 1424119_at 19079 Prkab1 6 - down both 393LN, 344 SQ catalytic subunit 0.020794 0.741493 0.00415 0.664342 RIKEN cDNA 1450274_at 75835 1700108E19Ri 6 - down both 393LN, 344 SQ 1700108E19 gene 0.039912 0.703106 0.00484 0.663873

solute carrier family 9 (sodium/hydrogen exchanger), member 1430932_at 77031 Slc9a8 6 - down both 393LN, 344 SQ 8 0.051379 0.717714 0.00991 0.663265 retinoic acid 1419415_a_at 19411 Rarg 6 - down both 393LN, 344 SQ receptor, gamma 0.021859 0.789076 0.0056 0.66248 threonyl-tRNA 1460323_at 110960 Tars 6 - down both 393LN, 344 SQ synthetase 0.009352 0.694434 0.00021 0.661127 transmembrane protease, serine 5 1418959_at 80893 Tmprss5 6 - down both 393LN, 344 SQ (spinesin) 0.005817 0.333146 0.20021 0.660845

1437087_at ------6 - down both 393LN, 344 SQ --- 0.081929 0.797854 0.00254 0.658552 A kinase (PRKA) 1436933_at 75547 Akap13 6 - down both 393LN, 344 SQ anchor protein 13 0.005839 0.594751 0.06926 0.655385

1429830_a_at 12509 Cd59a 6 - down both 393LN, 344 SQ CD59a antigen 0.03859 0.718942 0.00213 0.655078

Mammary gland RCB-0526 Jyg- MC(A) cDNA, RIKEN full-length enriched library, clone:G830022P11 product:unclassifiabl e, full insert sequence /// Notch gene homolog 4 1436901_at 18132 Notch4 6 - down both 393LN, 344 SQ (Drosophila) 0.000819 0.63114 0.00719 0.654497 RIKEN cDNA 1429029_at 74442 4933405A16Ri 6 - down both 393LN, 344 SQ 4933405A16 gene 0.003393 0.450687 0.01772 0.654197 neuromedin U 1425943_at 216749 Nmur2 6 - down both 393LN, 344 SQ receptor 2 0.006918 0.252721 0.32696 0.654165 PHD finger protein 1424170_at 68479 Phf5a 6 - down both 393LN, 344 SQ 5A 0.066725 0.805471 0.00234 0.653462 testis expressed 1439464_s_at 269536 Tex10 6 - down both 393LN, 344 SQ gene 10 0.123377 0.807681 0.00115 0.651769 Coronin, actin 1442972_at 23790 Coro1c 6 - down both 393LN, 344 SQ binding protein 1C 0.054947 0.680136 0.00291 0.651576

1422931_at 14284 Fosl2 6 - down both 393LN, 344 SQ fos-like antigen 2 0.006048 0.634079 0.01863 0.651366 ATPase, class II, 1415932_x_at 11981 Atp9a 6 - down both 393LN, 344 SQ type 9A 0.056148 0.748896 0.00357 0.650247 RIKEN cDNA 1424192_at 68948 1500011H22Ri6 - down both 393LN, 344 SQ 1500011H22 gene 0.016752 0.790011 0.00408 0.648514

6-phosphofructo-2- kinase/fructose-2,6- 1456888_at 270198 Pfkfb4 6 - down both 393LN, 344 SQ biphosphatase 4 0.014427 0.69351 0.00106 0.645714 open reading frame 1425122_at 52793 ORF9 6 - down both 393LN, 344 SQ 9 0.003721 0.700765 0.0003 0.645576

potassium channel tetramerisation domain containing 1436820_at 216858 Kctd11 6 - down both 393LN, 344 SQ 11 0.05593 0.799435 0.00518 0.644069 expressed sequence 1419969_at 245555 C77370 6 - down both 393LN, 344 SQ C77370 0.153364 0.792606 0.00997 0.64383

protein phosphatase 1, regulatory 1436590_at 244416 Ppp1r3b 6 - down both 393LN, 344 SQ (inhibitor) subunit 3B 5.22E-05 0.737448 0.00026 0.641201 transient receptor potential cation channel, subfamily 1435549_at 68667 Trpm4 6 - down both 393LN, 344 SQ M, member 4 0.005334 0.742326 0.00134 0.639862

non-SMC element 2 homolog (MMS21, 1424149_at 68501 Nsmce2 6 - down both 393LN, 344 SQ S. cerevisiae) 0.004716 0.641801 0.0182 0.639739

TatD DNase domain 1454769_at 381801 Tatdn2 6 - down both 393LN, 344 SQ containing 2 0.000117 0.647849 9.5E-05 0.638893 PHD finger protein 1418960_at 239510 Phf20l1 6 - down both 393LN, 344 SQ 20-like 1 0.137362 0.792173 0.00062 0.63812 RIKEN cDNA 1437451_at 68545 1110006O17R 6 - down both 393LN, 344 SQ 1110006O17 gene 0.003723 0.698711 0.00137 0.63622

1423028_at 15965 Ifna2 6 - down both 393LN, 344 SQ interferon alpha 2 0.091034 0.557643 0.00969 0.635009 RIKEN cDNA 1452584_at 69029 1500032L24Ri 6 - down both 393LN, 344 SQ 1500032L24 gene 0.014735 0.70516 0.00331 0.63499 RIKEN cDNA 1417139_at 66934 1700022L09Ri 6 - down both 393LN, 344 SQ 1700022L09 gene 0.007112 0.71899 0.00506 0.631608

coiled-coil-helix- coiled-coil-helix 1416938_at 66121 Chchd1 6 - down both 393LN, 344 SQ domain containing 1 0.002454 0.738496 0.00099 0.631152 autophagy-related 1439130_at 235040 Atg4d 6 - down both 393LN, 344 SQ 4D (yeast) 0.007255 0.593157 0.05737 0.630128

1448387_at 56438 Rbx1 6 - down both 393LN, 344 SQ ring-box 1 0.016044 0.683527 0.00162 0.630098

myb-like, SWIRM 1437202_at 320713 Mysm1 6 - down both 393LN, 344 SQ and MPN domains 1 0.064833 0.768753 0.00611 0.629342

ubiquitin-conjugating enzyme E2B, RAD6 homology (S. 1430177_at 22210 Ube2b 6 - down both 393LN, 344 SQ cerevisiae) 0.086461 0.791588 0.00138 0.628756 G protein-coupled 1450881_s_at 83924 Gpr137b 6 - down both 393LN, 344 SQ receptor 137B 0.154834 0.729223 0.00859 0.627447

Notch gene homolog 1421965_s_at 18131 Notch3 6 - down both 393LN, 344 SQ 3 (Drosophila) 0.009554 0.734081 0.00342 0.625104

1440670_at ------6 - down both 393LN, 344 SQ Transcribed locus 0.489878 0.897812 0.00219 0.624948

1458550_at 338367 Myo1d 6 - down both 393LN, 344 SQ myosin ID 0.106494 0.763843 0.00663 0.624579 lines homolog 2 1453153_at 72635 Lins2 6 - down both 393LN, 344 SQ (Drosophila) 0.026097 0.73139 0.00349 0.622669

1423987_at 66440 Cdc26 6 - down both 393LN, 344 SQ cell division cycle 26 0.064694 0.777305 0.00619 0.622153 phosphoribosyl pyrophosphate 1428543_at 231327 Ppat 6 - down both 393LN, 344 SQ amidotransferase 0.013863 0.678771 0.00021 0.620844

Rho GTPase 1434809_at 268970 Arhgap28 6 - down both 393LN, 344 SQ activating protein 28 0.011496 0.633543 0.00824 0.620086 InaD-like 1442244_at 12695 Inadl 6 - down both 393LN, 344 SQ (Drosophila) 0.039782 0.742531 0.00262 0.61969 echinoderm microtubule associated protein 1460366_at 225898 Eml3 6 - down both 393LN, 344 SQ like 3 0.099308 0.773429 0.00377 0.618968 RIKEN cDNA 1422296_at 66641 5730470L24Ri 6 - down both 393LN, 344 SQ 5730470L24 gene 0.002781 0.483383 0.13336 0.617734

ST3 beta- galactoside alpha- 2,3-sialyltransferase 1449078_at 54613 St3gal6 6 - down both 393LN, 344 SQ 6 0.02666 0.473449 0.00603 0.616827 tumor necrosis factor, alpha-induced 1433699_at 21929 Tnfaip3 6 - down both 393LN, 344 SQ protein 3 0.021652 0.593403 0.0078 0.616523 dual specificity 1418401_a_at 70686 Dusp16 6 - down both 393LN, 344 SQ phosphatase 16 0.000457 0.633186 0.00065 0.614891 germ cell-less homolog 1 1438888_at 23885 Gmcl1 6 - down both 393LN, 344 SQ (Drosophila) 0.015508 0.698005 0.00098 0.613187 sorbitol 1426584_a_at 20322 Sord 6 - down both 393LN, 344 SQ dehydrogenase 0.418231 0.881062 0.00235 0.613097

Pleiomorphic 1442235_at 54711 Plagl2 6 - down both 393LN, 344 SQ adenoma gene-like 2 0.035154 0.737431 0.00599 0.61304 triggering receptor expressed on 1460282_at 58217 Trem1 6 - down both 393LN, 344 SQ myeloid cells 1 0.004952 0.630388 0.09775 0.613028 RIKEN cDNA 1432850_at 71385 5430434G16R 6 - down both 393LN, 344 SQ 5430434G16 gene 0.004878 0.585342 0.00607 0.609354 death associated 1426915_at 69635 Dapk1 6 - down both 393LN, 344 SQ protein kinase 1 0.007329 0.672162 0.002 0.608104

1459802_at ------6 - down both 393LN, 344 SQ --- 0.067214 0.726887 0.00645 0.607645 RIKEN cDNA 1447704_s_at 78581 D530033C11R 6 - down both 393LN, 344 SQ D530033C11 gene 0.097065 0.775107 0.00248 0.6057

1442214_at 18028 Nfib 6 - down both 393LN, 344 SQ Nuclear factor I/B 0.060177 0.751438 0.00826 0.605655 multiple EGF-like- 1437057_at 230971 Megf6 6 - down both 393LN, 344 SQ domains 6 0.104052 0.734976 1.9E-05 0.605587

oxidoreductase NAD- binding domain 1426375_s_at 218885 Oxnad1 6 - down both 393LN, 344 SQ containing 1 0.014027 0.711446 0.0053 0.603646 Sphingosine-1- phosphate 1458035_at 433323 Sgpp2 6 - down both 393LN, 344 SQ phosphotase 2 0.108004 0.72989 0.00162 0.603369

stearoyl-coenzyme A 1450956_at 30049 Scd3 6 - down both 393LN, 344 SQ desaturase 3 0.0017 0.57619 0.00685 0.60266 killer cell lectin-like receptor, subfamily A, member 1 /// killer cell lectin-like receptor subfamily A, member 12 /// killer cell lectin-like receptor subfamily A, member 13 /// killer cell lectin-like receptor, subfamily A, member 4 /// killer cell lectin-like receptor, subfamily A, member 7 /// killer cell lectin-like receptor, subfamily A, member 15 /// killer cell lectin-like receptor subfamily A, member 23 /// killer cell lectin-like receptor subfamily A, member 20 /// killer cell lectin-like receptor subfamily A, member 22 /// killer cell lectin-like receptor, subfamily A, member 18 /// similar to killer cell lectin-like receptor subfamily A, member 1451664_x_at 16627 /// Klra1 /// Klra12 6 - down both 393LN, 344 SQ 13 0.019832 0.638132 0.00244 0.602281 ATPase, Ca++ transporting, cardiac muscle, slow twitch 1437797_at 11938 Atp2a2 6 - down both 393LN, 344 SQ 2 0.009077 0.656566 0.01914 0.601797

1439608_at ------6 - down both 393LN, 344 SQ Transcribed locus 0.005797 0.565225 0.02315 0.601386 microtubule associated serine/threonine 1417324_at 17776 Mast2 6 - down both 393LN, 344 SQ kinase 2 0.015495 0.718021 4.2E-05 0.601318

1420373_at 60611 Foxj2 6 - down both 393LN, 344 SQ forkhead box J2 0.119333 0.724146 0.00934 0.601043 Exostoses (multiple) 1458054_at 14042 Ext1 6 - down both 393LN, 344 SQ 1 0.101419 0.759603 0.00671 0.600814 InaD-like 1418984_at 12695 Inadl 6 - down both 393LN, 344 SQ (Drosophila) 0.029596 0.720914 8.4E-06 0.598978 calcium/calmodulin- dependent protein kinase kinase 1, 1418954_at 55984 Camkk1 6 - down both 393LN, 344 SQ alpha 0.014094 0.705205 0.00013 0.598092 membrane associated guanylate kinase, WW and PDZ 1451893_s_at 14924 Magi1 6 - down both 393LN, 344 SQ domain containing 1 0.013579 0.658536 0.00153 0.597416

1452209_at 227937 Pkp4 6 - down both 393LN, 344 SQ plakophilin 4 0.050162 0.73627 0.00141 0.597325

Mdm2, transformed 3T3 cell double minute p53 binding 1448638_at 105837 Mtbp 6 - down both 393LN, 344 SQ protein 0.078251 0.707823 0.00433 0.596965

1418417_at 17681 Msc 6 - down both 393LN, 344 SQ musculin 0.003767 0.307762 0.22335 0.595406

zinc finger, CSL 1433921_s_at 105638 Zcsl2 6 - down both 393LN, 344 SQ domain containing 2 0.000329 0.737206 0.00274 0.59441

pleckstrin homology domain containing, family B (evectins) 1416178_a_at 27276 Plekhb1 6 - down both 393LN, 344 SQ member 1 0.010434 0.622983 0.00345 0.593093 serine/arginine-rich protein specific 1417134_at 20817 Srpk2 6 - down both 393LN, 344 SQ kinase 2 0.061409 0.681328 0.00812 0.593089 male enhanced 1416810_at 17256 Mea1 6 - down both 393LN, 344 SQ antigen 1 0.019186 0.701135 0.00201 0.592076

ATP-binding cassette, sub-family C (CFTR/MRP), 1443206_at 76408 Abcc3 6 - down both 393LN, 344 SQ member 3 0.041564 0.709397 0.0043 0.591901

phosphoenolpyruvat e carboxykinase 2 1452620_at 74551 Pck2 6 - down both 393LN, 344 SQ (mitochondrial) 0.009857 0.756095 0.00481 0.591726 RIKEN cDNA 1452626_a_at 69064 1810014F10Ri 6 - down both 393LN, 344 SQ 1810014F10 gene 0.001455 0.643894 0.00104 0.591355

ATPase family, AAA 1436174_at 70472 Atad2 6 - down both 393LN, 344 SQ domain containing 2 0.053199 0.67512 0.00957 0.591222

1442659_at 211712 Pcdh9 6 - down both 393LN, 344 SQ protocadherin 9 0.003477 0.543289 0.00685 0.591066 nuclear factor, interleukin 3, 1418932_at 18030 Nfil3 6 - down both 393LN, 344 SQ regulated 0.035528 0.655551 0.00461 0.589785

1455043_at 238799 Tnpo1 6 - down both 393LN, 344 SQ transportin 1 0.052427 0.740011 0.0004 0.588904

par-6 (partitioning defective 6) homolog 1423175_s_at 58220 Pard6b 6 - down both 393LN, 344 SQ beta (C. elegans) 0.02304 0.646274 0.00702 0.588886

1450800_at 55925 Syt8 6 - down both 393LN, 344 SQ synaptotagmin VIII 0.005482 0.763027 0.00072 0.58697

expressed sequence 1436614_at 106945 AI843639 6 - down both 393LN, 344 SQ AI843639 0.004612 0.673683 0.00832 0.581906 RIKEN cDNA 1449150_at 77827 A930040G15R 6 - down both 393LN, 344 SQ A930040G15 gene 0.025804 0.65094 0.00381 0.579227

CKLF-like MARVEL transmembrane 1427964_at 70031 Cmtm8 6 - down both 393LN, 344 SQ domain containing 8 0.137461 0.703694 0.00323 0.57909 RIKEN cDNA 1424763_at 75564 1700027N10Ri6 - down both 393LN, 344 SQ 1700027N10 gene 0.004154 0.628994 0.00398 0.575516 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 1429459_at 108151 Sema3d 6 - down both 393LN, 344 SQ (semaphorin) 3D 0.064657 0.61994 0.00137 0.574338

expressed sequence 1447184_at 106717 AU021760 6 - down both 393LN, 344 SQ AU021760 0.009077 0.391799 0.19928 0.573583

expressed sequence 1427243_at 100532 AA536743 6 - down both 393LN, 344 SQ AA536743 0.050308 0.717732 0.00094 0.573472 kinesin family 1420987_at 16569 Kif3b 6 - down both 393LN, 344 SQ member 3B 0.004499 0.639534 0.00094 0.57306 Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1457404_at 80859 Nfkbiz 6 - down both 393LN, 344 SQ inhibitor, zeta 0.062731 0.664234 0.00602 0.572547 mitogen activated protein kinase 1419988_at 26409 Map3k7 6 - down both 393LN, 344 SQ kinase kinase 7 0.061173 0.773564 2.8E-05 0.572514 RAD18 homolog (S. 1443954_at 58186 Rad18 6 - down both 393LN, 344 SQ cerevisiae) 0.021871 0.603376 0.00364 0.572145 platelet-derived growth factor, D 1426319_at 71785 Pdgfd 6 - down both 393LN, 344 SQ polypeptide 0.009234 0.431429 0.03531 0.572034

expressed sequence 1445647_at 99627 AI447881 6 - down both 393LN, 344 SQ AI447881 0.035051 0.738163 0.00214 0.570392

Rho guanine nucleotide exchange 1440403_at 16801 Arhgef1 6 - down both 393LN, 344 SQ factor (GEF) 1 0.037591 0.70174 0.00136 0.570073 RIKEN cDNA 1440916_at 70291 2510049J12Rik6 - down both 393LN, 344 SQ 2510049J12 gene 0.099414 0.757379 0.00412 0.56937 retinol binding 1448754_at 19659 Rbp1 6 - down both 393LN, 344 SQ protein 1, cellular 0.012244 0.484706 0.00472 0.569314 poly A binding protein, cytoplasmic 1453840_at 18458 Pabpc1 6 - down both 393LN, 344 SQ 1 0.029906 0.665414 0.00323 0.568461 protein tyrosine phosphatase, 1423277_at 19272 Ptprk 6 - down both 393LN, 344 SQ receptor type, K 0.003798 0.732419 5.7E-05 0.566521

RIKEN cDNA 1456402_at 320026 A330076H08R 6 - down both 393LN, 344 SQ A330076H08 gene 0.001697 0.43489 0.12318 0.564515 ADP-ribosylation 1453590_at 75869 Arl5b 6 - down both 393LN, 344 SQ factor-like 5B 0.001202 0.63039 0.00434 0.561148 jumonji, AT rich interactive domain 1437106_at 214899 Jarid1a 6 - down both 393LN, 344 SQ 1A (Rbp2 like) 0.194678 0.739616 0.00736 0.556557

1460164_at 20729 Spin 6 - down both 393LN, 344 SQ spindlin 0.009605 0.734992 0.00363 0.556437 cingulin-like 1 /// similar to cingulin- 1421159_at 677485 // Cgnl1 /// LOC6 6 - down both 393LN, 344 SQ like 1 isoform 1 0.000379 0.166241 0.10209 0.555414 Suppressor of fused homolog 1446489_at 24069 Sufu 6 - down both 393LN, 344 SQ (Drosophila) 0.0052 0.633329 0.00054 0.553181 G protein-coupled receptor 137B /// similar to transmembrane 7 superfamily member 1439255_s_at 664862 // Gpr137b /// LO 6 - down both 393LN, 344 SQ 1 0.045753 0.574755 0.00252 0.551187 E2F transcription 1427462_at 13557 E2f3 6 - down both 393LN, 344 SQ factor 3 0.031755 0.730931 0.00038 0.55107 G protein-coupled 1419721_at 80885 Gpr109a 6 - down both 393LN, 344 SQ receptor 109A 0.165369 0.761516 0.00594 0.551027 cysteine-rich secretory protein LCCL domain 1423352_at 83691 Crispld1 6 - down both 393LN, 344 SQ containing 1 0.147229 0.702533 0.00552 0.549897 RIKEN cDNA 1429936_at 72614 2700059L22Ri 6 - down both 393LN, 344 SQ 2700059L22 gene 0.017979 0.530475 0.00139 0.549663

deleted in colorectal 1422162_at 13176 Dcc 6 - down both 393LN, 344 SQ carcinoma 0.002292 0.639308 0.04513 0.545737

sterile alpha motif 1429449_at 74480 Samd4 6 - down both 393LN, 344 SQ domain containing 4 0.000739 0.520041 0.00114 0.544243

RNA guanylyltransferase 1448714_at 24018 Rngtt 6 - down both 393LN, 344 SQ and 5'-phosphatase 5.32E-05 0.16494 0.16155 0.54402 RIKEN cDNA 1451441_at 70163 2210415F13Ri 6 - down both 393LN, 344 SQ 2210415F13 gene 0.122397 0.730598 0.00666 0.5437

1447606_x_at 66333 Aqp11 6 - down both 393LN, 344 SQ aquaporin 11 0.026922 0.733107 3.3E-05 0.54263 phosphoserine 1415673_at 100678 Psph 6 - down both 393LN, 344 SQ phosphatase 0.003036 0.704831 0.00011 0.542228 G protein-coupled receptor 137B /// similar to transmembrane 7 superfamily member 1439256_x_at 664862 // Gpr137b /// LO 6 - down both 393LN, 344 SQ 1 0.039297 0.56787 0.00321 0.542193 SMAD specific E3 ubiquitin protein 1443393_at 75788 Smurf1 6 - down both 393LN, 344 SQ ligase 1 0.056089 0.652477 0.00603 0.541791 G protein-coupled receptor 137B /// similar to transmembrane 7 superfamily member 1 /// similar to transmembrane 7 superfamily member 1450882_s_at 664862 // Gpr137b /// LO 6 - down both 393LN, 344 SQ 1 0.104573 0.696687 0.00882 0.539596

1434032_at ------6 - down both 393LN, 344 SQ --- 0.004848 0.642913 0.02348 0.538869

mucosa associated lymphoid tissue lymphoma 1456126_at 240354 Malt1 6 - down both 393LN, 344 SQ translocation gene 1 0.019149 0.705729 0.00664 0.538773 microsomal glutathione S- 1415897_a_at 56615 Mgst1 6 - down both 393LN, 344 SQ transferase 1 0.019906 0.695096 0.00533 0.537968 DNA segment, Chr 10, University of California at Los 1424779_at 28193 D10Ucla1 6 - down both 393LN, 344 SQ Angeles 1 0.004091 0.613489 0.01192 0.536589 adenylate kinase 3 1421829_at 11639 Ak3l1 6 - down both 393LN, 344 SQ alpha-like 1 0.052215 0.718776 0.00397 0.535622

1448694_at 16476 Jun 6 - down both 393LN, 344 SQ Jun oncogene 0.003429 0.692658 0.00039 0.533753

1449265_at 12362 Casp1 6 - down both 393LN, 344 SQ caspase 1 0.008255 0.645595 0.00309 0.533438 RIKEN cDNA 1434983_at 241116 B230363K08R 6 - down both 393LN, 344 SQ B230363K08 gene 0.008388 0.449897 0.06347 0.532164

1456849_at ------6 - down both 393LN, 344 SQ --- 0.043486 0.640643 0.00566 0.531956 polyhomeotic-like 1 1423212_at 13619 Phc1 6 - down both 393LN, 344 SQ (Drosophila) 0.009473 0.729215 7.6E-06 0.530311 RIKEN cDNA 1436362_x_at 77014 2700079J08Rik6 - down both 393LN, 344 SQ 2700079J08 gene 0.001707 0.35406 0.00528 0.529574

1456815_at 15218 Foxn1 6 - down both 393LN, 344 SQ forkhead box N1 0.102409 0.648404 0.00322 0.527644 SID1 transmembrane 1426551_at 320007 Sidt1 6 - down both 393LN, 344 SQ family, member 1 0.002121 0.391507 0.0271 0.527147

1419289_a_at 20972 Syngr1 6 - down both 393LN, 344 SQ synaptogyrin 1 0.006461 0.70944 0.00401 0.526425 RIKEN cDNA 1432059_x_at 75977 5031425E22Ri 6 - down both 393LN, 344 SQ 5031425E22 gene 0.051327 0.56512 0.00611 0.52625

1428197_at 109246 Tspan9 6 - down both 393LN, 344 SQ tetraspanin 9 0.024428 0.678986 0.00557 0.520534

1425291_at 15223 Foxj1 6 - down both 393LN, 344 SQ forkhead box J1 0.145696 0.648617 0.00626 0.518806 RIKEN cDNA 1424683_at 66270 1810015C04Ri6 - down both 393LN, 344 SQ 1810015C04 gene 0.012153 0.654486 2.9E-05 0.518315 prostaglandin E receptor 4 (subtype 1424208_at 19219 Ptger4 6 - down both 393LN, 344 SQ EP4) 0.001482 0.535624 0.04188 0.516504 1445894_at ------6 - down both 393LN, 344 SQ --- 0.0206 0.66573 0.00026 0.515805

1427537_at 223650 Eppk1 6 - down both 393LN, 344 SQ epiplakin 1 0.014512 0.597479 0.00174 0.512825 serine/arginine-rich protein specific 1417135_at 20817 Srpk2 6 - down both 393LN, 344 SQ kinase 2 0.065234 0.605072 0.00394 0.510439 Myosin, heavy polypeptide 10, non- 1441057_at 77579 Myh10 6 - down both 393LN, 344 SQ muscle 0.008364 0.52531 0.00927 0.508717 MAX dimerization 1434830_at 17119 Mxd1 6 - down both 393LN, 344 SQ protein 1 0.067206 0.628187 0.00961 0.507917

hypothetical protein 1427749_at 620893 LOC620893 6 - down both 393LN, 344 SQ LOC620893 0.047325 0.705781 0.00082 0.506461 RIKEN cDNA 1438228_at 74430 4930452B06Ri 6 - down both 393LN, 344 SQ 4930452B06 gene 0.0032 0.487016 0.00031 0.505514 RIKEN cDNA 1436194_at 77619 C330008K14R 6 - down both 393LN, 344 SQ C330008K14 gene 0.012509 0.56706 9.1E-05 0.504339

erythrocyte protein 1421090_at 13821 Epb4.1l1 6 - down both 393LN, 344 SQ band 4.1-like 1 0.006608 0.638095 0.00088 0.503123

1427102_at 20558 Slfn4 6 - down both 393LN, 344 SQ schlafen 4 0.005026 0.465697 0.02529 0.502043 pleckstrin homology domain containing, family G (with RhoGef domain) 1425073_at 213522 Plekhg6 6 - down both 393LN, 344 SQ member 6 0.013334 0.705043 0.00254 0.501971

protein phosphatase 1, regulatory (inhibitor) subunit 1434786_at 329251 Ppp1r12b 6 - down both 393LN, 344 SQ 12B 0.032055 0.68296 1.7E-05 0.500793 ribonucleotide reductase M2 B 1437221_at 382985 Rrm2b 6 - down both 393LN, 344 SQ (TP53 inducible) 0.296422 0.770752 0.00279 0.498535 PHD finger protein 1457264_at 239510 Phf20l1 6 - down both 393LN, 344 SQ 20-like 1 0.029553 0.500096 0.0047 0.497477 RIKEN cDNA 1433229_at 77301 9430031J08Rik6 - down both 393LN, 344 SQ 9430031J08 gene 0.004942 0.298756 0.09438 0.496891

potassium voltage- gated channel, shaker-related, 1441049_at 16494 Kcna6 6 - down both 393LN, 344 SQ subfamily, member 6 0.057235 0.680908 0.00253 0.496737 ARP1 actin-related protein 1 homolog B 1447293_x_at 226977 Actr1b 6 - down both 393LN, 344 SQ (yeast) 0.235877 0.748574 0.00518 0.495627

tumor necrosis factor receptor superfamily, 1422303_a_at 21936 Tnfrsf18 6 - down both 393LN, 344 SQ member 18 0.007152 0.693345 0.00379 0.493632 RIKEN cDNA 1431525_at 74554 9130002K18Ri 6 - down both 393LN, 344 SQ 9130002K18 gene 0.144446 0.674392 0.00095 0.490296 Solute carrier family 40 (iron-regulated transporter), member 1447227_at 53945 Slc40a1 6 - down both 393LN, 344 SQ 1 0.01905 0.671976 0.00033 0.489407 NudC domain 1449652_at 67429 Nudcd1 6 - down both 393LN, 344 SQ containing 1 0.122879 0.525653 0.00045 0.488787

transcription factor 1448977_at 21420 Tcfap2c 6 - down both 393LN, 344 SQ AP-2, gamma 0.106426 0.472806 0.00546 0.487948 adenylate kinase 3 1421830_at 11639 Ak3l1 6 - down both 393LN, 344 SQ alpha-like 1 0.004538 0.679572 9.5E-05 0.485469 RIKEN cDNA 1434144_s_at 76773 2410187C16Ri6 - down both 393LN, 344 SQ 2410187C16 gene 0.057054 0.683764 0.00123 0.485296 sodium channel, nonvoltage-gated, 1425088_at 20276 Scnn1a 6 - down both 393LN, 344 SQ type I, alpha 0.001376 0.590577 0.00067 0.48523 apolipoprotein B 1451755_a_at 11810 Apobec1 6 - down both 393LN, 344 SQ editing complex 1 0.062043 0.671317 0.00378 0.485043

1436789_at 380694 Ccnjl 6 - down both 393LN, 344 SQ cyclin J-like 0.024051 0.661588 0.00249 0.484817 gene model 440, 1434456_at 242819 Gm440 6 - down both 393LN, 344 SQ (NCBI) 0.005252 0.502464 0.00822 0.484016 prostate stem cell 1451258_at 72373 Psca 6 - down both 393LN, 344 SQ antigen 0.000349 0.412472 0.00201 0.475305 cDNA sequence 1455241_at 242125 BC037703 6 - down both 393LN, 344 SQ BC037703 0.000394 0.464383 0.00022 0.475019

rod outer segment 1448996_at 19881 Rom1 6 - down both 393LN, 344 SQ membrane protein 1 0.016205 0.567706 0.00147 0.471527 ankyrin repeat 1438756_at 225187 Ankrd29 6 - down both 393LN, 344 SQ domain 29 0.018908 0.358157 0.00164 0.470393

transforming growth 1421943_at 21802 Tgfa 6 - down both 393LN, 344 SQ factor alpha 0.003123 0.66046 0.00037 0.469523 G protein-coupled 1453072_at 71862 Gpr160 6 - down both 393LN, 344 SQ receptor 160 0.011338 0.590068 0.00224 0.468158 myeloid leukemia 1418589_a_at 17349 Mlf1 6 - down both 393LN, 344 SQ factor 1 0.000868 0.300711 0.00683 0.46725 NF-kappaB 1445983_at 77286 Nkrf 6 - down both 393LN, 344 SQ repressing factor 0.004598 0.4092 0.02735 0.466882

RIKEN cDNA 1457270_at 320013 B230343A10R 6 - down both 393LN, 344 SQ B230343A10 gene 0.006669 0.496118 0.00458 0.463239

1446509_at 228608 Smox 6 - down both 393LN, 344 SQ spermine oxidase 0.135783 0.602964 0.00287 0.462721

1436291_a_at 64705 Dpys 6 - down both 393LN, 344 SQ dihydropyrimidinase 0.270123 0.771862 0.00018 0.462015 cDNA sequence 1451779_at 232491 BC027061 6 - down both 393LN, 344 SQ BC027061 0.020752 0.661027 0.0002 0.460424 RIKEN cDNA 1424365_at 67704 1810037I17Rik6 - down both 393LN, 344 SQ 1810037I17 gene 0.014024 0.637523 7.5E-05 0.458876 RIKEN cDNA 1453004_at 73102 3110004L20Ri 6 - down both 393LN, 344 SQ 3110004L20 gene 0.005232 0.629452 7.2E-06 0.45862

1419735_at 12994 Csn3 6 - down both 393LN, 344 SQ casein kappa 0.002507 0.395761 0.02109 0.458409

1418741_at 16421 Itgb7 6 - down both 393LN, 344 SQ integrin beta 7 0.002915 0.311624 0.0377 0.45799 RIKEN cDNA 1455162_at 230603 4922503N01Ri6 - down both 393LN, 344 SQ 4922503N01 gene 0.011503 0.578642 0.00012 0.457575 aryl hydrocarbon receptor nuclear 1429688_at 272322 Arntl2 6 - down both 393LN, 344 SQ translocator-like 2 0.487878 1.078716 0.00133 0.455213

procollagen-proline, 2-oxoglutarate 4- dioxygenase (proline 4-hydroxylase), 1417149_at 18452 P4ha2 6 - down both 393LN, 344 SQ alpha II polypeptide 0.070571 0.6803 0.00078 0.454724 wingless-related MMTV integration 1423367_at 22421 Wnt7a 6 - down both 393LN, 344 SQ site 7A 0.002618 0.440029 5.8E-06 0.453813

colony stimulating factor 2 (granulocyte- 1427429_at 12981 Csf2 6 - down both 393LN, 344 SQ macrophage) 0.059467 0.605836 0.00033 0.452345 serine/arginine-rich protein specific 1417136_s_at 20817 Srpk2 6 - down both 393LN, 344 SQ kinase 2 0.05041 0.561747 0.00683 0.446494

1439322_at 211712 Pcdh9 6 - down both 393LN, 344 SQ Protocadherin 9 0.004674 0.373236 0.01107 0.445462

CEA-related cell 1450494_x_at 26365 Ceacam1 6 - down both 393LN, 344 SQ adhesion molecule 1 0.002352 0.357184 0.00525 0.441264 RIKEN cDNA 1438982_s_at 76917 2810417J12Rik6 - down both 393LN, 344 SQ 2810417J12 gene 6.49E-05 0.532036 0.00065 0.438015

1441442_at ------6 - down both 393LN, 344 SQ --- 0.005696 0.599888 0.00443 0.43353

erythrocyte protein 1460592_at 13821 Epb4.1l1 6 - down both 393LN, 344 SQ band 4.1-like 1 0.012088 0.558241 0.00053 0.433044 kinesin family 1447236_at 16564 Kif21a 6 - down both 393LN, 344 SQ member 21A 0.002138 0.318719 0.02573 0.432782 mitochondrial ribosomal protein 1448190_at 66845 Mrpl33 6 - down both 393LN, 344 SQ L33 0.020098 0.633065 0.00076 0.427633 tumor suppressor 1453386_at 69136 Tusc1 6 - down both 393LN, 344 SQ candidate 1 0.001025 0.373992 0.00887 0.421668

T-cell receptor gamma chain /// region containing T- cell receptor gamma chain; T-cell receptor 1422189_x_at 110067 // Tcrg /// LOC67 6 - down both 393LN, 344 SQ gamma, variable 4 0.05685 0.583971 0.0037 0.416732

1431811_a_at 78938 Fbxo34 6 - down both 393LN, 344 SQ F-box only protein 34 0.002278 0.545726 0.03098 0.408685 Slit homolog 2 1437978_at 20563 Slit2 6 - down both 393LN, 344 SQ (Drosophila) 0.000869 0.182062 0.08631 0.404598 growth arrest 1417859_at 14457 Gas7 6 - down both 393LN, 344 SQ specific 7 0.000167 0.46453 0.00062 0.40218 peroxisome proliferator activated receptor binding 1450402_at 19014 Pparbp 6 - down both 393LN, 344 SQ protein 0.044504 0.613984 0.00177 0.400545 SLIT-ROBO Rho GTPase activating 1425741_at 259302 Srgap3 6 - down both 393LN, 344 SQ protein 3 0.085849 0.558706 0.00702 0.398858 transglutaminase 1, 1451416_a_at 21816 Tgm1 6 - down both 393LN, 344 SQ K polypeptide 0.023242 0.547974 0.00123 0.39823

ATPase, class I, 1455396_at 54670 Atp8b1 6 - down both 393LN, 344 SQ type 8B, member 1 0.127343 0.64546 0.00208 0.393453

eosinophil- associated, ribonuclease A family, member 1 /// eosinophil- associated, ribonuclease A family, member 2 /// eosinophil- associated, ribonuclease A family, member 3 /// eosinophil- associated, ribonuclease A 1422411_s_at 13586 /// Ear1 /// Ear2 ///6 - down both 393LN, 344 SQ family, member 12 0.050945 0.62049 2.2E-05 0.391258

myosin, heavy polypeptide 14 /// similar to nonmuscle 1428835_at 672865 // Myh14 /// LOC66 - down both 393LN, 344 SQ myosin heavy chain 0.000275 0.43809 5.9E-05 0.374158

1419738_a_at 22004 Tpm2 6 - down both 393LN, 344 SQ tropomyosin 2, beta 0.024704 0.589339 8.5E-05 0.372821 dual specificity 1440615_at 70686 Dusp16 6 - down both 393LN, 344 SQ phosphatase 16 0.002554 0.384377 0.02622 0.36864

stimulated by 1422723_at 20897 Stra6 6 - down both 393LN, 344 SQ retinoic acid gene 6 0.010611 0.296542 0.00203 0.365383

1440686_at 213171 Prss27 6 - down both 393LN, 344 SQ protease, serine 27 0.024126 0.554842 6.8E-05 0.36273 heat-responsive 1428326_s_at 15473 Hrsp12 6 - down both 393LN, 344 SQ protein 12 0.001452 0.482624 0.00012 0.360073 calcium/calmodulin- dependent protein 1452050_at 227541 Camk1d 6 - down both 393LN, 344 SQ kinase ID 0.002835 0.414686 0.00029 0.359892

1419880_x_at ------6 - down both 393LN, 344 SQ Transcribed locus 0.017741 0.387044 0.00996 0.358424 cytochrome c oxidase, subunit VIIa 1418709_at 12865 Cox7a1 6 - down both 393LN, 344 SQ 1 0.031653 0.456143 0.00794 0.357959

multiple C2 domains, 1430439_at 78771 Mctp1 6 - down both 393LN, 344 SQ transmembrane 1 0.06139 0.547001 0.00469 0.334372 protocadherin 9 /// similar to protocadherin 9 1429861_at 211712 // Pcdh9 /// LOC66 - down both 393LN, 344 SQ isoform 1 precursor 0.006615 0.26155 0.01894 0.332044 RIKEN cDNA 1427975_at 75668 2210403B10Ri 6 - down both 393LN, 344 SQ 2210403B10 gene 0.081996 0.515875 0.00674 0.330222 RIKEN cDNA 1428960_at 71233 4933434I06Rik6 - down both 393LN, 344 SQ 4933434I06 gene 0.026513 0.5864 0.00024 0.329838

1443295_at ------6 - down both 393LN, 344 SQ Transcribed locus 0.137881 0.587101 0.00517 0.327997

fibronectin type III 1449012_s_at 64339 Fndc4 6 - down both 393LN, 344 SQ domain containing 4 0.006825 0.451827 0.00555 0.326384

1417409_at 16476 Jun 6 - down both 393LN, 344 SQ Jun oncogene 0.001731 0.548814 0.00169 0.324861 phosphodiesterase 1449403_at 18585 Pde9a 6 - down both 393LN, 344 SQ 9A 0.002233 0.342944 0.01678 0.317893

Down syndrome cell 1441082_at 13508 Dscam 6 - down both 393LN, 344 SQ adhesion molecule 0.094592 0.5597 0.00145 0.315367 G protein-coupled 1439795_at 237175 Gpr64 6 - down both 393LN, 344 SQ receptor 64 0.004491 0.212147 0.00373 0.306357 CAMP responsive element binding 1442576_at 231991 Creb5 6 - down both 393LN, 344 SQ protein 5 0.023359 0.445534 0.00084 0.302999

Expressed sequence 1446139_at 224833 AI661453 6 - down both 393LN, 344 SQ AI661453 0.056084 0.49177 0.00391 0.302136

bone morphogenetic 1440706_at 12164 Bmp8b 6 - down both 393LN, 344 SQ protein 8b 0.003562 0.27162 0.00324 0.297448

T-cell receptor gamma chain /// region containing T- cell receptor gamma chain; T-cell receptor 1450521_a_at 110067 // Tcrg /// LOC67 6 - down both 393LN, 344 SQ gamma, variable 4 0.05798 0.49016 0.00373 0.296217 RIKEN cDNA 1424404_at 76261 0610040J01Rik6 - down both 393LN, 344 SQ 0610040J01 gene 0.000176 0.373246 3E-05 0.292862

v-crk sarcoma virus CT10 oncogene 1425604_at 12929 Crkl 6 - down both 393LN, 344 SQ homolog (avian)-like 0.000971 0.240182 1.9E-06 0.292545

solute carrier family 1423865_at 100434 Slc44a1 6 - down both 393LN, 344 SQ 44, member 1 2.5E-05 0.489345 3.1E-06 0.292154 RIKEN cDNA 1425233_at 78354 2210407C18Ri6 - down both 393LN, 344 SQ 2210407C18 gene 0.021994 0.424566 0.00297 0.291981

DnaJ (Hsp40) homolog, subfamily 1446686_at 230935 Dnajc11 6 - down both 393LN, 344 SQ C, member 11 0.123131 0.562352 0.00277 0.288204 eosinophil- associated, ribonuclease A 1422412_x_at 53876 Ear3 6 - down both 393LN, 344 SQ family, member 3 0.083355 0.559419 0.00104 0.276847 phosphoinositide-3- kinase adaptor 1429831_at 83490 Pik3ap1 6 - down both 393LN, 344 SQ protein 1 0.00228 0.511124 0.0003 0.276283

1434016_at 387524 Znrf2 6 - down both 393LN, 344 SQ zinc and ring finger 2 0.005448 0.484001 0.00014 0.276154

1441439_at 83428 Ucn3 6 - down both 393LN, 344 SQ urocortin 3 0.035308 0.380482 0.0042 0.262508 BCL2/adenovirus E1B 19kD interacting protein 1420683_at 171388 Bnipl 6 - down both 393LN, 344 SQ like 0.024491 0.293695 0.00022 0.261944

1417561_at 11812 Apoc1 6 - down both 393LN, 344 SQ apolipoprotein C-I 0.000205 0.300182 0.00512 0.261939 RIKEN cDNA 1424494_s_at 76917 2810417J12Rik6 - down both 393LN, 344 SQ 2810417J12 gene 0.000825 0.484185 0.00025 0.26178

pleiomorphic 1426208_x_at 22634 Plagl1 6 - down both 393LN, 344 SQ adenoma gene-like 1 0.00158 0.461461 0.00013 0.257871 zinc finger protein 1458267_at 72720 Zfp248 6 - down both 393LN, 344 SQ 248 0.001643 0.129739 0.03704 0.25687 expressed sequence 1457046_s_at 245555 C77370 6 - down both 393LN, 344 SQ C77370 0.121976 0.477414 0.00342 0.255728 sarcosine 1416662_at 192166 Sardh 6 - down both 393LN, 344 SQ dehydrogenase 0.186136 0.585311 0.00614 0.252801 RIKEN cDNA 1433396_at 66703 4921504P13Ri 6 - down both 393LN, 344 SQ 4921504P13 gene 0.004668 0.171646 0.0193 0.248608 RIKEN cDNA 1452766_at 72948 2900041A09Ri 6 - down both 393LN, 344 SQ 2900041A09 gene 0.00073 0.149875 0.01557 0.244712

1416006_at 17242 Mdk 6 - down both 393LN, 344 SQ midkine 0.006073 0.229806 0.00849 0.239849 proline rich protein 1450837_at 19131 Prh1 6 - down both 393LN, 344 SQ HaeIII subfamily 1 0.000319 0.133672 0.01154 0.235195

bone morphogenetic 1450342_at 12164 Bmp8b 6 - down both 393LN, 344 SQ protein 8b 8.52E-05 0.161756 4.5E-05 0.22409 protein kinase, cAMP dependent regulatory, type I 1434325_x_at 19085 Prkar1b 6 - down both 393LN, 344 SQ beta 0.025177 0.446285 0.00047 0.219735 myosin, light polypeptide 7, 1449071_at 17898 Myl7 6 - down both 393LN, 344 SQ regulatory 0.008989 0.261209 0.00349 0.219392

1420713_a_at 17240 Mdfi 6 - down both 393LN, 344 SQ MyoD family inhibitor 0.038751 0.425251 0.00551 0.218305

1417917_at 12797 Cnn1 6 - down both 393LN, 344 SQ calponin 1 0.006275 0.107576 0.0355 0.212273 RIKEN cDNA 1429457_at 76943 2310020A21Ri 6 - down both 393LN, 344 SQ 2310020A21 gene 0.02829 0.484401 8.4E-05 0.207756

solute carrier organic anion transporter 1448918_at 108116 Slco3a1 6 - down both 393LN, 344 SQ family, member 3a1 0.006552 0.415548 0.00024 0.205909 CDNA clone 1440910_at ------6 - down both 393LN, 344 SQ IMAGE:5252333 0.112687 0.539541 0.0024 0.193315 1458783_at ------6 - down both 393LN, 344 SQ --- 0.058664 0.34351 0.004 0.191033

solute carrier organic anion transporter 1434537_at 108116 Slco3a1 6 - down both 393LN, 344 SQ family, member 3a1 0.000588 0.284907 3.3E-05 0.189832 chemokine (C-X-C 1419728_at 20311 Cxcl5 6 - down both 393LN, 344 SQ motif) ligand 5 0.012057 0.318052 0.00273 0.170021

Pleckstrin homology, Sec7 and coiled-coil 1446268_at 19159 Pscd3 6 - down both 393LN, 344 SQ domains 3 0.214053 0.581402 0.00988 0.16563 Scm-like with four 1434353_at 353282 Sfmbt2 6 - down both 393LN, 344 SQ mbt domains 2 0.041521 0.281152 0.00823 0.147169

CEA-related cell 1425675_s_at 26365 Ceacam1 6 - down both 393LN, 344 SQ adhesion molecule 1 0.004938 0.275464 0.00052 0.143159

1450460_at 11828 Aqp3 6 - down both 393LN, 344 SQ aquaporin 3 0.026161 0.338024 0.00109 0.135515

similar to WD repeat and SOCS box containing protein 2 (WSB-2) (SOCS box- containing WD 1446195_at 632689 LOC632689 6 - down both 393LN, 344 SQ protein SWiP-2) 0.024525 0.262626 0.00083 0.124766

CEA-related cell 1427630_x_at 26365 Ceacam1 6 - down both 393LN, 344 SQ adhesion molecule 1 0.004484 0.218175 0.00295 0.123649 purinergic receptor P2Y, G-protein 1421456_at 18441 P2ry1 6 - down both 393LN, 344 SQ coupled 1 0.022996 0.34629 9.8E-05 0.112968

gamma-aminobutyric acid (GABA-A) 1451424_at 216643 Gabrp 6 - down both 393LN, 344 SQ receptor, pi 0.004151 0.293939 6.3E-05 0.112464

carbonic anhydrase 8 /// similar to Carbonic anhydrase- related protein 1427482_a_at 12319 /// Car8 /// LOC676 - down both 393LN, 344 SQ (CARP) (CA-VIII) 0.186379 0.698158 0.00029 0.112104

CEA-related cell 1425538_x_at 26365 Ceacam1 6 - down both 393LN, 344 SQ adhesion molecule 1 0.005561 0.199741 0.00077 0.096292 premature ovarian 1427492_at 69693 Pof1b 6 - down both 393LN, 344 SQ failure 1B 0.02439 0.33548 3.7E-06 0.085539

expressed sequence 1418734_at 497653 BE136769 6 - down both 393LN, 344 SQ BE136769 0.09024 0.422158 0.00043 0.080627 RIKEN cDNA 1452730_at 66184 1110033J19Rik6 - down both 393LN, 344 SQ 1110033J19 gene 0.00733 0.223586 5.7E-06 0.077947

chloride channel 1451823_at 229927 Clca4 6 - down both 393LN, 344 SQ calcium activated 4 0.004456 0.153737 0.00019 0.048247

1429891_at 75568 Capsl 6 - down both 393LN, 344 SQ calcyphosine-like 0.000268 0.097756 2.2E-05 0.048032 CEA-related cell adhesion molecule 1 /// CEA-related cell 1460682_s_at 26365 /// Ceacam1 /// Ce6 - down both 393LN, 344 SQ adhesion molecule 2 0.000541 0.12693 1.8E-06 0.024605

1454890_at 27494 Amot 6 - down both 393LN, 344 SQ angiomotin 0.000675 0.090276 2E-05 0.020472 RIKEN cDNA 1430858_at 77043 4632433K11Ri 7 - up 393LN, down 344SQ 4632433K11 gene 0.007958 1.814495 0.64226 1.022778 1455797_x_at 16865 Lgtn 7 - up 393LN, down 344SQ ligatin 0.007017 1.518168 0.14914 0.851971

origin recognition complex, subunit 6- 1417037_at 56452 Orc6l 7 - up 393LN, down 344SQ like (S. cerevisiae) 0.007943 1.71301 0.30547 0.835219 RIKEN cDNA 1448947_at 66523 2810004N23Ri7 - up 393LN, down 344SQ 2810004N23 gene 0.003186 1.51708 0.01524 0.800899 PDZ domain 1451269_at 72621 Pdzd11 7 - up 393LN, down 344SQ containing 11 0.000509 1.554856 0.00629 0.795772 cell division cycle 34 homolog (S. 1434879_at 216150 Cdc34 7 - up 393LN, down 344SQ cerevisiae) 0.004749 1.576383 0.0237 0.789399 polymerase (DNA 1419397_at 18968 Pola1 7 - up 393LN, down 344SQ directed), alpha 1 0.005805 1.654384 0.09932 0.775575 histidyl tRNA 1451040_at 66044 Hars2 7 - up 393LN, down 344SQ synthetase 2 0.001208 1.729557 0.02996 0.768125

translocase of inner mitochondrial membrane 8 1416346_at 30058 Timm8a1 7 - up 393LN, down 344SQ homolog a1 (yeast) 0.000237 1.897646 0.05313 0.765651 enolase 3, beta 1417951_at 13808 Eno3 7 - up 393LN, down 344SQ muscle 0.007109 1.870194 0.15643 0.76546

Rho GTPase 1426027_a_at 78514 Arhgap10 7 - up 393LN, down 344SQ activating protein 10 0.005952 1.83503 0.21097 0.737874

acyl-CoA synthetase long-chain family 1451257_at 216739 Acsl6 7 - up 393LN, down 344SQ member 6 0.000533 3.454816 0.24752 0.689737

cysteine conjugate- 1428151_x_at 70266 Ccbl1 7 - up 393LN, down 344SQ beta lyase 1 0.00787 1.724339 0.02408 0.679726 pseudouridine 1418869_a_at 56361 Pus1 7 - up 393LN, down 344SQ synthase 1 0.027468 1.237922 0.00039 0.665799

protein prenyltransferase alpha subunit repeat 1431073_at 72351 Ptar1 7 - up 393LN, down 344SQ containing 1 0.064664 1.590924 0.00348 0.665301 polycomb group ring 1424081_at 71041 Pcgf6 7 - up 393LN, down 344SQ finger 6 0.222586 1.189516 0.00098 0.650813

coiled-coil-helix- coiled-coil-helix 1417233_at 72170 Chchd4 7 - up 393LN, down 344SQ domain containing 4 0.015867 1.245644 4.4E-05 0.650656 aldo-keto reductase family 1, member B3 (aldose reductase) /// similar to Aldose reductase (AR) (Aldehyde reductase) /// similar to Aldose reductase (AR) (Aldehyde reductase) /// similar to Aldose reductase (AR) (Aldehyde reductase) /// similar to Aldose reductase (AR) (Aldehyde reductase) /// similar to Aldose reductase (AR) (Aldehyde 1448319_at 11677 /// Akr1b3 /// LOC 7 - up 393LN, down 344SQ reductase) 0.007923 1.367272 0.00138 0.64954

threonine synthase- 1452605_at 208967 Thnsl1 7 - up 393LN, down 344SQ like 1 (bacterial) 0.015962 1.388556 0.00019 0.649154 1431554_a_at 71790 Anxa9 7 - up 393LN, down 344SQ annexin A9 0.017155 1.274977 0.00559 0.647081

protein phosphatase 1, regulatory 1456072_at 243725 Ppp1r9a 7 - up 393LN, down 344SQ (inhibitor) subunit 9A 0.00026 2.531698 0.00891 0.642556 zinc finger protein 1451216_at 30932 Zfp330 7 - up 393LN, down 344SQ 330 4.03E-05 1.618293 0.02724 0.640447 nuclear receptor subfamily 2, group 1418605_at 22025 Nr2c1 7 - up 393LN, down 344SQ C, member 1 0.113853 1.210628 0.00545 0.637605

glucose-6-phosphate dehydrogenase X- 1448354_at 14381 G6pdx 7 - up 393LN, down 344SQ linked 0.005803 1.46923 0.00063 0.628435 polymerase (DNA 1434229_a_at 18970 Polb 7 - up 393LN, down 344SQ directed), beta 0.234882 1.264005 0.00177 0.623185 RIKEN cDNA 1423879_at 225995 D030056L22Ri7 - up 393LN, down 344SQ D030056L22 gene 0.232921 1.200558 0.0047 0.620887 RIKEN cDNA 1432518_at 78109 4930430J20Rik7 - up 393LN, down 344SQ 4930430J20 gene 0.195167 1.315432 0.00961 0.619367

methenyltetrahydrofo late synthetase 1439152_at 234814 Mthfsd 7 - up 393LN, down 344SQ domain containing 0.008808 1.378686 0.00125 0.61515 thyroid hormone receptor interactor 1418092_s_at 106628 Trip10 7 - up 393LN, down 344SQ 10 0.026169 1.553767 0.00808 0.607338 RIKEN cDNA 1457611_x_at 66488 2010309E21Ri 7 - up 393LN, down 344SQ 2010309E21 gene 0.1286 1.29591 0.00708 0.601257 bone marrow stromal 1449453_at 12182 Bst1 7 - up 393LN, down 344SQ cell antigen 1 0.001112 4.663637 0.01791 0.601108 myc induced nuclear 1451042_a_at 67014 Mina 7 - up 393LN, down 344SQ antigen 0.019865 1.600096 0.00533 0.599144 engulfment and cell motility 3, ced-12 homolog (C. 1434489_at 234683 Elmo3 7 - up 393LN, down 344SQ elegans) 0.023492 1.322288 0.00052 0.599108

aldo-keto reductase family 1, member B3 1437133_x_at 11677 Akr1b3 7 - up 393LN, down 344SQ (aldose reductase) 0.034598 1.349382 0.00325 0.598721 1459333_at ------7 - up 393LN, down 344SQ Transcribed locus 0.053606 1.539217 0.00557 0.594635 TROVE domain 1436533_at 20822 Trove2 7 - up 393LN, down 344SQ family, member 2 0.097315 1.26142 0.00021 0.592816 RIKEN cDNA 1424315_at 68001 1110004E09Ri 7 - up 393LN, down 344SQ 1110004E09 gene 0.062383 1.424091 0.00129 0.590003

1434877_at 18164 Nptx1 7 - up 393LN, down 344SQ neuronal pentraxin 1 0.002609 2.299966 0.18015 0.586352 tyrosine kinase, non- 1448298_at 51789 Tnk2 7 - up 393LN, down 344SQ receptor, 2 0.087038 1.702338 0.00795 0.577352

mitochondrial 1447585_s_at 121022 Mrps6 7 - up 393LN, down 344SQ ribosomal protein S6 0.137271 1.35236 0.00553 0.567706

polymerase (DNA directed), beta /// RIKEN cDNA 1434230_at 18970 /// Polb /// A430087 - up 393LN, down 344SQ A430088C08 gene 0.111493 1.284915 0.00051 0.563649

bone marrow stromal 1449454_at 12182 Bst1 7 - up 393LN, down 344SQ cell antigen 1 0.000755 5.520516 0.05615 0.559844

coiled-coil-helix- coiled-coil-helix 1438659_x_at 66098 Chchd6 7 - up 393LN, down 344SQ domain containing 6 0.09361 1.360933 0.00203 0.558674 methylthioadenosine 1424426_at 66902 Mtap 7 - up 393LN, down 344SQ phosphorylase 0.006403 1.650496 0.08707 0.546475 glycosyltransferase- 1434007_at 228366 Gyltl1b 7 - up 393LN, down 344SQ like 1B 0.115523 1.448705 0.00979 0.541163 calcium and integrin binding family 1422852_at 56506 Cib2 7 - up 393LN, down 344SQ member 2 0.150117 1.603671 0.0048 0.536038 HtrA serine 1460495_s_at 64704 Htra2 7 - up 393LN, down 344SQ peptidase 2 0.117917 1.300495 0.00071 0.534844 MAM domain 1453152_at 71738 Mamdc2 7 - up 393LN, down 344SQ containing 2 0.416176 1.498115 0.00269 0.516379 phosphomannomuta 1424167_a_at 29858 Pmm1 7 - up 393LN, down 344SQ se 1 0.069866 1.397829 0.00297 0.513291 uridine 1448562_at 22271 Upp1 7 - up 393LN, down 344SQ phosphorylase 1 0.114426 1.899689 0.00924 0.510634 HtrA serine 1436269_s_at 64704 Htra2 7 - up 393LN, down 344SQ peptidase 2 0.052889 1.30095 0.00061 0.488022 calcitonin-related 1422639_at 116903 Calcb 7 - up 393LN, down 344SQ polypeptide, beta 0.534975 5.744437 0.0054 0.475379 1422673_at 18760 Prkcm 7 - up 393LN, down 344SQ protein kinase C, mu 0.189956 1.78719 0.00792 0.410528 1418051_at 13848 Ephb6 7 - up 393LN, down 344SQ Eph receptor B6 0.191694 1.524703 0.0042 0.403959 tetratricopeptide 1436237_at 69480 Ttc9 7 - up 393LN, down 344SQ repeat domain 9 0.028064 1.914076 0.00301 0.398239

signal transducer and activator of transcription 1415774_at 58523 Statip1 7 - up 393LN, down 344SQ interacting protein 1 0.110253 1.56366 0.00025 0.354782 hook homolog 2 1419350_at 170833 Hook2 7 - up 393LN, down 344SQ (Drosophila) 0.012879 1.805982 1.4E-05 0.350681 RIKEN cDNA 1427082_at 74032 4632417N05Ri7 - up 393LN, down 344SQ 4632417N05 gene 0.03117 1.57423 3.3E-05 0.349261 1450276_a_at 20259 Scin 7 - up 393LN, down 344SQ scinderin 0.0361 2.271925 0.00032 0.346884 Hspb associated 1428566_at 66667 Hspbap1 7 - up 393LN, down 344SQ protein 1 0.007194 1.954176 0.05162 0.342854

RIKEN cDNA 1447623_s_at 399614 C130009A20R 7 - up 393LN, down 344SQ C130009A20 gene 0.120457 2.464121 0.0081 0.335239 RIKEN cDNA 1434301_at 399603 D330050I23Rik7 - up 393LN, down 344SQ D330050I23 gene 0.001017 3.166584 1.9E-06 0.261916 1449091_at 54420 Cldn8 7 - up 393LN, down 344SQ claudin 8 0.017799 3.99881 0.00549 0.195141 RIKEN cDNA 1440339_at 73762 4833416E15Ri 7 - up 393LN, down 344SQ 4833416E15 gene 2.13E-05 4.132381 0.00034 0.05867 1449426_a_at 26359 Anxa10 8 - down 393LN, up 344SQ annexin A10 0.005144 0.312753 0.00063 7.188614

1449989_at 17225 Mcpt2 8 - down 393LN, up 344SQ mast cell protease 2 0.005218 0.156147 0.00062 5.863274 1421134_at 11839 Areg 8 - down 393LN, up 344SQ amphiregulin 0.003868 0.498719 2.4E-05 5.819519 inactive X specific 1427262_at 213742 Xist 8 - down 393LN, up 344SQ transcripts 0.007927 0.034191 0.25449 3.975342 3-hydroxymethyl-3- methylglutaryl- Coenzyme A lyase- 1434913_at 208982 Hmgcll1 8 - down 393LN, up 344SQ like 1 0.000732 0.366408 7.8E-05 3.642442

RIKEN cDNA 1435640_x_at 319269 A130040M12R8 - down 393LN, up 344SQ A130040M12 gene 0.402785 0.917256 0.00493 3.626967

1422352_at 17224 Mcpt1 8 - down 393LN, up 344SQ mast cell protease 1 0.006926 0.195289 0.01488 3.521859 hepatic nuclear 1427001_s_at 15378 Hnf4a 8 - down 393LN, up 344SQ factor 4, alpha 0.306105 0.79802 2.1E-05 3.419295 RIKEN cDNA 1454051_at 72125 2600011E07Ri 8 - down 393LN, up 344SQ 2600011E07 gene 0.017799 0.303033 0.00295 3.231999 eosinophil- associated, ribonuclease A 1425295_at 93726 Ear11 8 - down 393LN, up 344SQ family, member 11 0.006088 0.483331 0.19004 2.721121 1428891_at ------8 - down 393LN, up 344SQ --- 0.159112 0.700209 0.0015 2.556297 RIKEN cDNA 1430462_at 71886 2310002L09Ri 8 - down 393LN, up 344SQ 2310002L09 gene 0.595672 0.96515 0.00832 2.371109 transmembrane 1433735_a_at 100201 Tmem64 8 - down 393LN, up 344SQ protein 64 0.147907 0.724597 0.00594 2.218597

deafness, autosomal dominant 5 homolog 1417903_at 54722 Dfna5h 8 - down 393LN, up 344SQ (human) 0.03645 0.691988 0.00229 2.067831 kin of IRRE like 3 1431402_at 67703 Kirrel3 8 - down 393LN, up 344SQ (Drosophila) 0.043227 0.703509 0.0016 2.050757 transmembrane 6 superfamily member 1425079_at 107770 Tm6sf2 8 - down 393LN, up 344SQ 2 0.052532 0.60414 0.00042 2.046901 fatty acid desaturase 1418773_at 60527 Fads3 8 - down 393LN, up 344SQ 3 0.06211 0.685645 0.00784 2.015319 RIKEN cDNA 1431371_at 71535 9030411M13R 8 - down 393LN, up 344SQ 9030411M13 gene 0.164422 0.605921 0.00784 1.934487 BAI1-associated 1424951_at 66898 Baiap2l1 8 - down 393LN, up 344SQ protein 2-like 1 0.031173 0.699391 0.00072 1.92909 RIKEN cDNA 1455377_at 70892 4921517B04Ri 8 - down 393LN, up 344SQ 4921517B04 gene 0.08235 0.673501 0.00718 1.894721 NOL1/NOP2/Sun domain family, 1429572_at 70918 Nsun7 8 - down 393LN, up 344SQ member 7 0.018629 0.469575 0.00263 1.862052 NIPA-like domain 1456321_at 70701 Npal1 8 - down 393LN, up 344SQ containing 1 0.012212 0.574639 0.0059 1.851541 platelet-derived growth factor, C 1449351_s_at 54635 Pdgfc 8 - down 393LN, up 344SQ polypeptide 0.158566 0.765385 0.00189 1.818118

progesterone receptor membrane 1423451_at 53328 Pgrmc1 8 - down 393LN, up 344SQ component 1 0.127532 0.676278 0.00472 1.81537 RIKEN cDNA 1445363_at 77994 2810055G20R 8 - down 393LN, up 344SQ 2810055G20 gene 0.008785 0.284423 0.11472 1.775495 1433595_at ------8 - down 393LN, up 344SQ --- 0.160222 0.775524 0.00032 1.762017 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, 1425906_a_at 20349 Sema3e 8 - down 393LN, up 344SQ (semaphorin) 3E 0.09981 0.777187 0.00484 1.717968 platelet-derived growth factor, C 1419123_a_at 54635 Pdgfc 8 - down 393LN, up 344SQ polypeptide 0.111867 0.757023 0.00048 1.717542 1417496_at 12870 Cp 8 - down 393LN, up 344SQ ceruloplasmin 0.006362 0.55635 0.09311 1.678248 NIPA-like domain 1453345_at 70701 Npal1 8 - down 393LN, up 344SQ containing 1 0.028597 0.683509 0.00027 1.670487 mannosidase, endo- 1455403_at 242362 Manea 8 - down 393LN, up 344SQ alpha 0.261963 0.826864 0.0006 1.6622

expressed sequence 1443442_at 101250 AU022084 8 - down 393LN, up 344SQ AU022084 0.450232 0.877386 0.00303 1.64476

1451021_a_at 12224 Klf5 8 - down 393LN, up 344SQ Kruppel-like factor 5 0.130946 0.806321 0.00021 1.63248 exocyst complex 1455385_at 107371 Exoc6 8 - down 393LN, up 344SQ component 6 0.002333 0.624239 0.01948 1.616426 homeodomain interacting protein 1428433_at 15258 Hipk2 8 - down 393LN, up 344SQ kinase 2 0.041563 0.647394 0.00551 1.615342 RIKEN cDNA 1444182_at 70080 2210010C17Ri8 - down 393LN, up 344SQ 2210010C17 gene 0.000584 0.68495 0.00077 1.60394 AHNAK nucleoprotein 1428058_at 66395 Ahnak 8 - down 393LN, up 344SQ (desmoyokin) 0.008821 0.543195 0.57812 1.591753 protocadherin beta 1418941_at 93893 Pcdhb22 8 - down 393LN, up 344SQ 22 0.099126 0.839087 0.00298 1.574541 exocyst complex 1435631_x_at 107371 Exoc6 8 - down 393LN, up 344SQ component 6 0.003485 0.6126 0.01681 1.569066 dedicator of cyto- 1452220_at 330662 Dock1 8 - down 393LN, up 344SQ kinesis 1 0.018623 0.809353 0.00077 1.559563 G protein-coupled 1434672_at 73010 Gpr22 8 - down 393LN, up 344SQ receptor 22 0.482367 0.934245 0.00048 1.532166 CDNA sequence 1440872_at 218236 BC010304 8 - down 393LN, up 344SQ BC010304 0.136367 0.711703 0.00142 1.530307 RAB27b, member RAS oncogene 1417214_at 80718 Rab27b 8 - down 393LN, up 344SQ family 0.005375 0.709665 0.00374 1.521296

vacuolar protein 1439187_at 230895 Vps13d 8 - down 393LN, up 344SQ sorting 13 D (yeast) 0.191916 0.850064 0.00561 1.502074

expressed sequence 1433610_at 212439 AA986860 8 - down 393LN, up 344SQ AA986860 0.005446 0.530264 0.25185 1.424416 1448734_at 12870 Cp 8 - down 393LN, up 344SQ ceruloplasmin 0.007349 0.582753 0.07186 1.380573 ribosomal protein 1460442_at 20085 Rps19 8 - down 393LN, up 344SQ S19 0.007573 0.62032 0.03659 1.357106

guanine nucleotide binding protein, 1454959_s_at 14677 Gnai1 8 - down 393LN, up 344SQ alpha inhibiting 1 0.006161 0.616838 0.18408 1.325785 1416808_at 18073 Nid1 8 - down 393LN, up 344SQ nidogen 1 0.000257 0.578087 0.06487 1.262961