Jefferies 2019 Global Healthcare Conference

You are invited to attend the Jefferies 2019 Global Healthcare Conference taking place June 4-7 at the Grand Hyatt in New York City.

Following the sugccess of our 2018 conference, with over 400 participating companies and 2,700 attendees, we will again feature an extensive range of public & private healthcare companies across AGENDA the Biopharmaceuticals, Life Sciences, Healthcare Services, Healthcare IT and Medical Technology JUNE 4-7, 2019 sectors. This global gathering of leading executives, institutional investors, private equity investors and VCs will address near- and long-term investment opportunities and discuss the mechanisms driving Grand Hyatt healthcare in the U.S. and internationally. New York, NY The four-day conference will be comprised of company presentations, Q&A breakout sessions, keynotes & thematic panels. Company management teams and investors will also have the opportunity to participate in 1x1 and small group meetings.

To add this conference to your Microsoft Outlook calendar, click here.

REGISTRATION: Please contact your Jefferies representative

PARTICIPATING COMPANIES: www.jefferies.com/060419

HOTEL INFORMATION: Jefferies has reserved a block of rooms at the Grand Hyatt New York (109 E. 42nd Street at Grand Central Terminal) at a negotiated rate of $445 per night (plus tax). Rooms are based on availability and reservations must be made by Monday, May 13 in order to guarantee the conference rate. Please note that rooms must be cancelled by 3pm EST at least 72 hours prior to arrival. To make a reservation, please click here. For any questions, you can call the hotel directly at 1-800-233-1234.

QUESTIONS: [email protected]

AGENDA TUESDAY, JUNE 4, 2019 Jefferies 2019 Global Healthcare Conference

BALLROOM 1 BALLROOM 2 BALLROOM 3 BALLROOM 4 BALLROOM 5 MOROSCO IMPERIAL BREAKOUT: URIS BREAKOUT: JUILLIARD BREAKOUT: BROADWAY BREAKOUT: CARNEGIE HALL BREAKOUT: ALVIN BREAKOUT: PLYMOUTH BREAKOUT: BOOTH 7:30 AM Breakfast & Registration

8:00 AM Albireo Pharma, Inc. (ALBO) Ultragenyx Pharmaceutical Sartorius AG (SARTF) Twist Bioscience Corporation Menlo Therapeutics Inc. NantCell, Inc. (Private) Biotechnology Inc. (RARE) MedTech (TWST) (MNLO) Biotechnology Ron Cooper, President & CEO Biotechnology Rainer Lehmann, CFO; Life Sciences Biotechnology Patrick Soon-Shiong, CEO & Shalini Sharp, CFO Ben Orzelek, Head of IR Emily Leproust, CEO Steve Basta, CEO Chairman

8:30 AM Heska Corporation (HSKA) Swedish Orphan Biovitrum QIAGEN N.V. (QGEN) Medpace Holdings, Inc. Quotient Limited (QTNT) NantKwest, Inc. (NK) Pandion Therapeutics, Inc. Animal Health AB (SOBI SS) Life Sciences (MEDP) MedTech Biotechnology (Private) Kevin Wilson, CEO & President Biotechnology Peer Schatz, CEO Healthcare Services Chris Lindop, CFO Patrick Soon-Shiong, Chairman Biotechnology Guido Oelkers, CEO August Troendle, President & & CEO Anthony Coyle, President & CEO; Jesse Geiger, CFO & CEO COO, Laboratory Operations

9:00 AM Surgery Partners, Inc. (SGRY) NovoCure Limited (NVCR) Lonza Group Ltd (LONN VX) Urogen Pharma Ltd. (URGN) miRagen Therapeutics, Inc. Lyra Therapeutics (Private) Arcutis, Inc. (Private) Healthcare Services MedTech Biotechnology Biotechnology (MGEN) Biotechnology Pharmaceuticals Tom Cowhey, CFO Bill Doyle, Executive Chairman Rodolfo Savitzky, CFO Liz Barrett, CEO Biotechnology Maria Palasis, President & CEO Frank Watanabe, President & William Marshall, President & CEO CEO

9:30 AM Knight Therapeutics Inc. Allogene Therapeutics, Inc. Cerner Corporation (CERN) Mithra Women's Health Eagle Pharmaceuticals, Inc. Scholar Rock, Inc. (SRRK) Intuity Medical, Inc. (Private) (04K GR) (ALLO) HCIT (MITRA BB) (EGRX) Pharmaceuticals MedTech Pharmaceuticals Biotechnology Marc Naughton, EVP & CFO Pharmaceuticals Pharmaceuticals Nagesh Mahanthappa, Emory Anderson, President & Samira Sakhia, President Eric Schmidt, CFO Alexandra Deschner, IR Officer Scott Tarriff, CEO; President & CEO CEO Pete Meyers, CFO

10:00 AM Addus HomeCare PRA Health Sciences, Inc. Bio-Rad Laboratories (BIO) Pacira BioSciences, Inc. Translate Bio, Inc. (TBIO) Nordic Nanovector ASA Cadent Therapeutics Corporation (ADUS) (PRAH) Life Sciences (PCRX) Biotechnology (NANO NO) (Private) Healthcare Services Healthcare Services Norman Schwartz, President; Pharmaceuticals Ronald Renaud, CEO Biotechnology Pharmaceuticals Dirk Allison, President & CEO; Colin Shannon, CEO; Ilan Daskal, CFO Dave Stack, CEO Eduardo Bravo, CEO O Jodie Morrison, CEO Brian Poff, EVP & CFO Mike Bonello, CFO

10:30 AM Surmodics, Inc. (SRDX) Retrophin, Inc. (RTRX) Teladoc Health (TDOC) Viking Therapeutics, Inc. CytomX Therapeutics, Inc. Indivior PLC (INDV LN) MedTech Biotechnology Healthcare Services (VKTX) (CTMX) Pharmaceuticals Gary Maharaj, President & Eric Dube, CEO Jason Gorevic, CEO; Biotechnology Biotechnology Shaun Thaxter, CEO CEO; Tim Arens, VP of Finance Valerie Haertel, IR Brian Lian, President & CEO Sean McCarthy, President, CEO & CFO & Chairman

11:00 AM Vanda Pharmaceuticals Inc. LivaNova PLC (LIVN) Humana Inc. (HUM) Acadia Healthcare Company, OptiNose, Inc. (OPTN) Dova Pharmaceuticals, Inc. KSQ Therapeutics, Inc. (VNDA) MedTech Healthcare Services Inc. (ACHC) Pharmaceuticals (DOVA) (Private) Biotechnology Damien McDonald, CEO Brian Kane, CFO Healthcare Services Peter Miller, CEO Pharmaceuticals Biotechnology Mihales Polymeropoulos, M.D., Debbie Osteen, CEO; David Zaccardelli, CEO David P. Meeker Meeker, CEO President & CEO; Jim Kelly, David Duckworth, CFO EVP, CFO & Treasurer

11:30 AM HMS Holdings Corp. (HMSY) H. Lundbeck A/S (LUN DC) Roche Holding AG (ROG VX) bluebird bio, Inc. (BLUE) CRISPR Therapeutics AG Establishment Labs Holdings Urovant Sciences Ltd. (UROV) Healthcare Services Pharmaceuticals Pharmaceuticals Biotechnology (CRSP) Inc. (ESTA) Pharmaceuticals Jeff Sherman, EVP & CFO Peter Anastasiou, EVP, Alan Hippe, CFO Roche Chip Baird, CFO Biotechnology MedTech Keith Katkin, President & CEO; Lundbeck North America Sam Kulkarni, CEO Nick Lewin, Chairman; Juan Cornelia Haag-Molkenteller, Jose Chacon Quiros, CEO; CMO; Michael McFadden, Renee Gaeta, CFO Chief Commercial Officer

AGENDA TUESDAY, JUNE 4, 2019 Jefferies 2019 Global Healthcare Conference

12:15 PM KEYNOTE: “Drug Pricing: The Politics and Outlook” Ted Kennedy, Jr., Partner, Epstein Becker Green & Lynn Shapiro Snyder, Senior Member, Epstein Becker Green (12:15PM-1:00PM)

1:30 PM Fluidigm Corporation United Therapeutics Centene Corporation (CNC) Amedisys, Inc. (AMED) Xeris Pharmaceuticals, Inc. IGM Biosciences, Inc. (FLDM) Corporation (UTHR) Healthcare Services Healthcare Services (XERS) (Private) Life Sciences Biotechnology Ed Kroll, SVP, Finance & IR Paul Kusserow, CEO Pharmaceuticalsv Biotechnology Vikram Jog, CFO James Edgemond, CFO & Paul Edick, CEO Fred M. Schwarzer, CEO Treasurer

2:00 PM BioScrip, Inc. (BIOS) NextGen Healthcare, Inc. The Cooper Companies, Inc. Veloxis Pharmaceuticals A/S Bellicum Pharmaceuticals, Veru Inc. (VERU) Aura Biosciences, Inc. Healthcare Services (NXGN) (COO) (VELO DC) Inc. (BLCM) Pharmaceuticals (Private) Dan Greenleaf, President & HCIT MedTech Pharmaceuticals Biotechnology Mitchell Steiner, Chairman, Biotechnology CEO; Steve Deitsch, SVP, CFO Rusty Frantz, President & CEO Brian Andrews, SVP, CFO & Craig Collard, CEO Atabak Mokari, CFO President CEO Elisabet de los Pinos, CEO & Treasurer Treasurer

2:30 PM Ra Pharmaceuticals, Inc. MEDNAX, Inc. (MD) Mettler-Toledo International Aerie Pharmaceuticals, Inc. Corbus Pharmaceuticals Collegium Pharmaceutical, Catalyst Biosciences, Inc. (RARX) Healthcare Services Inc. (MTD) (AERI) Holdings, Inc. (CRBP) Inc. (COLL) (CBIO) Biotechnology Charles Lynch, VP, Strategy Life Sciences Pharmaceuticals Pharmaceuticals Pharmaceuticals Biotechnology Doug Treco, President & CEO Shawn Vadala, CFO Vince Anido, Chairman & CEO Yuval Cohen, CEO Joe Ciaffoni, CEO; Nassim Usman, President & Paul Brannelly, EVP & CFO CEO; Fletcher Payne, CFO; Howard Levy, CMO

3:00 PM BioArctic AB (BIOAB LN) West Pharmaceutical Hologic Inc. (HOLX) Vocera Communications, Inc. Akebia Therapeutics, Inc. Verrica Pharmaceuticals Inc. Minerva Neurosciences, Inc. Biotechnology Services, Inc. (WST) MedTech (VCRA) (AKBA) (VRCA) (NERV) Gunilla Osswald, CEO; MedTech Karleen Oberton, CFO; HCIT Biotechnology Pharmaceuticals Biotechnology Johanna Fälting, VP, Eric Green, CEO & President Michael Watts, VP, IR & Brent Lang, CEO; Sue Dooley, John Butler, CEO Ted White, President & CEO Remy Luthringer, Executive Translational Science & Corp Communications Head of IR Chairman & CEO Pharmacology

3:30 PM Banca Farmafactoring S.p.a. Corcept Therapeutics Exact Sciences Corporation Apellis Pharmaceuticals, Inc. PDL BioPharma, Inc. (PDLI) EUSA Pharma Ltd (Private) . Galapagos NV (GLPG NA) (BFF IM) Incorporated (CORT) (EXAS) (APLS) Pharmaceuticals Pharmaceuticals Biotechnology Healthcare Services Pharmaceuticals Life Sciences Biotechnology Dominique Monnet, President Lee Morley, CEO Onno van de Stolpe, CEO Massimiliano Belingheri, CEO; Joseph Belanoff, CEO Kevin Conroy, President & Cedric Francois, CEO & CEO; Peter Garcia, CFO Emanuele Bona, CFO; Enrico CEO Tadiotto, Head of IR, Strategy, M&A; Nazareno Ciccarello, Multinationals Development Manager

4:00 PM Arcus Biosciences, Inc. Luminex Corporation Aurora Cannabis Inc. Dicerna Pharmaceuticals, BioDelivery Sciences Kiadis Pharma N.V. (KDS NA) Metacrine, Inc. (Private) (RCUS) (LMNX) (ACB) Inc. (DRNA) International, Inc. (BDSI) Biotechnology Biotechnology Biotechnology Life Sciences Cannabis Biotechnology Pharmaceuticals Arthur Lahr, CEO Ken Song, CEO Terry Rosen, CEO; Katherine Homi Shamir, President & CEO Cam Battley, Chief Corporate Doug Fambrough, CEO Herm Cukier, CEO Bock, VP, IR & Corp Strategy Officer

4:30 PM Orasure Technologies, Inc. HEXO Corp. (HEXO B3) Abiomed Inc (ABMD) R1 RCM Inc. (RCM) Camurus (CAMX SS) Compugen Ltd. (CGEN) (OSUR) Cannabis MedTech Healthcare Services Pharmaceuticals Biotechnology Life Sciences Sebastien St-Louis, CEO & Michael Minogue, CEO; Todd Joe Flanagan, President & CEO; Fredrik Tiberg, President & Anat Cohen-Dayag, President Stephen Tang, President & Co-Founder Trapp, CFO Chris Ricaurte, CFO & CEO & CEO CEO; Roberto Cuca, CFO Treasurer

AGENDA WEDNESDAY, JUNE 5, 2019 Jefferies 2019 Global Healthcare Conference

8:00 AM Acorda Therapeutics, Inc. MorphoSys AG (MOR GR) Alcon, Inc. (ACL) Intra-Cellular Therapies, Inc. Castlight Health, Inc. (CSLT) Sierra Oncology, Inc. (SRRA Aileron Therapeutics, Inc. (ACOR) Biotechnology Healthcare Services (ITCI) HCIT Biotechnology (ALRN) Biotechnology Jens Holstein, CFO David Endicott, CEO; Biotechnology Siobhan Nolan Mangini, CFO Dr. Nick Glover, President & Biotechnology Ron Cohen, M.D., President & Tim Stonesifer, CFO; Christina Sharon Mates, CEO CEO Manuel Aivado, President & CEO Cheng, Global Head, IR CEO; Donald Dougherty, SVP & CFO

8:30 AM Atara Biotherapeutics, Inc. Charles River Laboratories Esperion (ESPR) Amphastar Pharmaceuticals, Aeglea BioTherapeutics, Inc. Verona Pharma plc (VRNA) (ATRA) International, Inc. (CRL) Pharmaceuticals Inc. (AMPH) (AGLE) Biotechnology Biotechnology Healthcare Services Jason Shandell, President; Pharmaceuticals Biotechnology Jan-Anders Karlsson, CEO; Dietmar Berger, M.D., Ph.D., David Smith, EVP & CFO Bill Peters, CFO Jason Shandell, President; Anthony Quinn, CEO Piers Morgan, CFO Global Head of Research & Bill Peters, CFO Development

9:00 AM TG Therapeutics, Inc. (TGTX) Brooks Automation, Inc. Array BioPharma Inc. (ARRY) CareDx, Inc (CDNA) Synthorx, Inc. (THOR) Assembly Biosciences, Inc. Enzyvant (Private) Biotechnology (BRKS) Biotechnology Biotechnology Biotechnology (ASMB) Pharmaceuticals Michael Weiss, CEO Life Sciences Ron Squarer, CEO Peter Maag, CEO Marcos Milla, Chief Scientific Biotechnology Rachelle Jacques, CEO Steve Schwartz, President & Officer Richard Colonno, EVP & CSO CEO; Lindon Robertson, EVP & Virology Operations CFO

9:30 AM Cara Therapeutics, Inc. ICON Plc (ICLR) Bio-Techne Corporation U.S. Physical Therapy, Inc. Kezar Life Sciences, Inc. Oncorus, Inc. (Private) Beam Therapeutics Inc. (CARA) Healthcare Services (TECH) (USPH) (KZR) Biotechnology (Private) Biotechnology Steve Cutler, CEO Life Sciences Healthcare Services Biotechnology Ted Ashburn, CEO Biotechnology Derek Chalmers, CEO Chuck Kummeth, CEO Christopher Reading, CEO John Fowler, CEO John Evans, CEO

10:00 AM Rubius Therapeutics, Inc. OSI Systems, Inc. (OSIS) PANEL: Trends in Healthcare Coherus Biosciences, Inc. Kiniksa Pharmaceuticals, Ltd. Affimed N.V. (AFMD) Equillium, Inc. (EQ) (RUBY) MedTech Private Equity (CHRS) (KNSA) Biotechnology Biotechnology Biotechnology Alan Edrick, EVP & CFO Biotechnology Biotechnology Adi Hoess, CEO Daniel Bradbury, Chairman & Pablo Cagnoni, CEO Denny Lanfear, President & Sanj K. Patel, CEO & Chairman CEO CEO of the Board; John Paolini, CMO

10:30 AM BioCryst Pharmaceuticals, Syneos Health, Inc. (SYNH) Cosmo Pharmaceuticals N.V. TCR2 Therapeutics Inc. Concert Pharmaceuticals, Inc. Poxel SA (POXEL FP) Inc. (BCRX) Healthcare Services (COPN SW) (TCRR) (CNCE) Biotechnology Biotechnology Alistair Macdonald, CEO Pharmaceuticals Biotechnology Biotechnology Thomas Kuhn, CEO Jon Stonehouse, CEO Alessandro Della Cha, CEO Ian Somaiya, CFO Roger Tung, President & CEO

11:00 AM Corvus Pharmaceuticals, Inc. Chemed Corporation (CHE) Medtronic plc (MDT) Immunomedics, Inc. (IMMU) Xenon Pharmaceuticals Inc. Constellation BlueRock Therapeutics (CRVS) Healthcare Services MedTech Biotechnology (XENE) Pharmaceuticals, Inc. (CNST) (Private) Biotechnology Kevin McNamara, President & Mike Coyle, EVP & President, Behzad Aghazadeh, Executive Biotechnology Biotechnology Biotechnology Richard Miller, President & CEO Cardiac & Vascular Group Chairman Simon Pimstone, CEO Jigar Raythatha, CEO Emile Nuwaysir, CEO O CEO

11:30 AM PureTech Health plc (PRTC Iovance Biotherapeutics, Inc. Gilead Sciences, Inc. (GILD) Kadmon Holdings, Inc. Replimune Group, Inc. Orexo AB (ORX SS) Intec Pharma Ltd. (NTEC) LN) (IOVA) Biotechnology (KDMN) (REPL) Pharmaceuticals Biotechnology Biotechnology Biotechnology Dan O'Day, Chairman & CEO Biotechnology Biotechnology Joseph DeFeo, EVP & CFO; Jeffrey Meckler, Vice Chairman Daphne Zohar, Founder & Maria Fardis, President & CEO; Harlan Waksal, President & Philip Astley-Sparkle, Executive Robert DeLuca, President & CEO CEO Timothy Morris, CFO CEO Chairman & Director Orexo US Inc

AGENDA WEDNESDAY, JUNE 5, 2019 Jefferies 2019 Global Healthcare Conference

12:15 PM Craig B.Thompson, MD, President and CEO of Memorial Sloan Kettering Cancer Center ~ Moderated by Brian Friedman, President, Jefferies Financial Group

1:00 PM Michael R. Bloomberg, Founder, Bloomberg LP and Bloomberg Philanthropies & 108th Mayor of the City of New York ~ Moderated by Brian Friedman, President, Jefferies Financial Group 2:00 PM WAVE Life Sciences Ltd. Reata Pharmaceuticals, Inc. Genomic Health, Inc. (GHDX) Supernus Pharmaceuticals, Odonate Therapeutics, Inc. GlycoMimetics, Inc. (GLYC) Passage BIO, Inc. (Private) (WVE) (RETA) Life Sciences Inc. (SUPN) (ODT) Biotechnology Life Sciences Biotechnology Biotechnology Kim Popovits, CEO; Brad Cole, Pharmaceuticals Pharmaceuticals Rachel King, CEO Stephen Squinto, Interim CEO Paul Bolno, President & CEO TBD CFO; Emily Faucette, VP, IR Jack Khattar, CEO Kevin Tang, CEO

2:30 PM Abeona Therapeutics Inc. UDG Healthcare plc (UDG Align Technology Inc. Autolus Therapeutics plc Rigel Pharmaceuticals, Inc. Seres Therapeutics, Inc. Yumanity Therapeutics Inc. (ABEO) LN) (ALGN) (AUTL) (RIGL) (MCRB) (Private) Biotechnology Healthcare Services MedTech Biotechnology Biotechnology Biotechnology Biotechnology João Siffert, CEO, CMO & Liam Logue, Head of Corp John Morici, CFO Christian Itin, CEO Dean Schorno, CFO Eric Shaff, President & CEO Tony Coles, CEO Head of R&D Development

3:00 PM Stealth BioTherapeutics Epizyme, Inc. (EPZM) Heron Therapeutics, Inc. AxoGen, Inc. (AXGN) AMAG Pharmaceuticals, Inc. Karyopharm Therapeutics Arbutus Biopharma Incorporated (MITO) Biotechnology (HRTX) MedTech (AMAG) Inc. (KPTI) Corporation (ABUS) Pharmaceuticals Robert Bazemore, President & Biotechnology Karen Zaderej, Chairman, Pharmaceuticals Biotechnology Biotechnology Reenie McCarthy, CEO CEO Barry Quart, President & CEO President & CEO Bill Heiden, CEO; Ted Myles, Michael Kauffman, CEO Mark Murray, President & CEO CFO

3:30 PM Cassiopea S.p.A. (SKIN SW) Orion Corporation Canopy Growth Corporation Spectrum Pharmaceuticals, Aclaris Therapeutics, Inc. EyePoint Pharmaceuticals, BELLUS Health Inc. (BLU CN) Pharmaceuticals (ORNBV FH) (CGC) Inc. (SPPI) (ACRS) Inc. (EYPT) Biotechnology Diana Harbort, CEO Pharmaceuticals Cannabis Biotechnology Biotechnology Biotechnology Roberto Bellini, President & Jari Karlson, CFO Bruce Linton, Chairman & CEO Joe Turgeon, CEO & President Neal Walker, President & CEO; Nancy Lurker, President & CEO CEO Stuart Shanler, CSO; Mike Tung, SVP, IR

4:00 PM Tabula Rasa HealthCare, Inc. Zai Lab Limited (ZLAB) Blueprint Medicines Allscripts Healthcare Hanger, Inc. (HNGR) LHC Group, Inc. (LHCG) ALX Oncology (Private) (TRHC) Biotechnology ls Corporation (BPMC) Solutions, Inc. (MDRX) Healthcare Services Healthcare Services Biotechnology Healthcare Services Tao Fu, President & COO Biotechnology Healthcare Services Thomas Kiraly, CFO; Keith Myers, Chairman & CEO; Jaume Pons, CEO Brian Adams, CFO Kate Haviland, COO Dennis Olis, CFO Seth Frank, VP, Treasury & IR Josh Proffitt, CFO

4:30 PM Evolus, Inc. (EOLS) Healthcare Services Group, Integra LifeSciences Holdings Brookdale Senior Living Inc. Cytosorbents Corporation CTI BioPharma Corp. (CTIC) Cardiva Medical, Inc. Pharmaceuticals Inc. (HCSG) Corporation (IART) (BKD) (CTSO) Biotechnology (Private) David Moatazedi, President & Healthcare Services MedTech Healthcare Services MedTech Bruce Seeley, COO MedTech CEO; Lauren Silvernail, CFO & ed Wahl, President & CEO; Peter Arduini, President & CEO Cindy Baier, CEO; Steve Swain, Phillip Chan, CEO & President John Russell, CEO EVP, Corp Development Matt McKee, Chief EVP & CFO Communications Officer

AGENDA THURSDAY, JUNE 6, 2019 Jefferies 2019 Global Healthcare Conference

8:00 AM NuCana plc (NCNA) Lexicon Pharmaceuticals, Inc. Idorsia Pharmaceuticals Ltd ObsEva SA (OBSV) Sol-Gel Technologies Ltd. Allena Pharmaceuticals, Inc. Sonendo, Inc. (Private) Biotechnology (LXRX) (IDIA SW) Biotechnology (SLGL) (ALNA) MedTech Hugh Griffith, CEO Biotechnology Pharmaceuticals Ernest Loumaye, Co-Founder & Pharmaceuticals Biotechnology Bjarne Bergheim, President & Jeffrey Wade, EVP & CFO Andrew Weiss, Head of IR & CEO; Tim Adams, CFO Alon Seri-Levy, CEO Louis Brenner, President & CEO CEO Corp Communications 8:30 AM Zynerba Pharmaceuticals, Recipharm AB (RECIB SS) Repligen Corporation (RGEN) ViewRay, Inc. (VRAY) Mersana Therapeutics, Inc. Strongbridge Biopharma plc ORIC Pharmaceuticals, Inc. Inc. (ZYNE) Healthcare Services Life Sciences MedTech (MRSN) (SBBP) (Private) Pharmaceuticals Thomas Eldered, CEO Jon Snodgres, CFO Scott Drake, President & CEO Biotechnology Biotechnology Pharmaceuticals Armando Anido, CEO Anna Protopapas, President & Matthew Pauls, President & Jacob Chacko, CEO CEO CEO

9:00 AM Cross Country Healthcare, Intercept Pharmaceuticals, Medidata Solutions, Inc. Veracyte, Inc. (VCYT) ADMA Biologics, Inc. (ADMA) Ardelyx, Inc. (ARDX) Maravai Life Sciences Inc. Inc. (CCRN) Inc. (ICPT) (MDSO) Life Sciences Pharmaceuticals Biotechnology (Private) Healthcare Services Biotechnology HCIT Bonnie Anderson, Chairman & Adam Grossman, President & Michael Raab, President & CEO Life Sciences Kevin Clark, President & CEO Mark Pruzanski, President, CEO Rouven Bergmann, CFO CEO CEO; Brian Lenz, VP & CFO Kevin Herde, CFO & Director

9:30 AM Georgia Healthcare Group Arrowhead Pharmaceuticals, Amarin Corporation plc Milestone Pharmaceuticals Five Prime Therapeutics, Inc. Kyn Therapeutics Inc. Tmunity Therapeutics, Inc. PLC (GHG LN) Inc. (ARWR) (AMRN) Inc. (MIST) (FPRX) (Private) (Private) Healthcare Services Biotechnology Biotechnology Pharmaceuticals Biotechnology Biotechnology Biotechnology Michael Oliver, IR Chris Anzalone, President John Thero, President & CEO Joe Oliveto, CEO Aron Knickerbocker, CEO Mark Manfredi, CEO Usman "Oz" Azam, CEO

10:00 AM Cryoport, Inc. (CYRX) Cambrex Corporation (CBM) Madrigal Pharmaceuticals, ZIOPHARM Oncology, Inc. Merus N.V. (MRUS) Acer Therapeutics Inc. (ACER) SQZ Biotechnologies Life Sciences Healthcare Services Inc. (MDGL) (ZIOP) Biotechnology Pharmaceuticals Company (Private) Robert Stefanovich, CFO Shawn Cavanagh, EVP & COO Biotechnology Biotechnology Ton Logtenberg, CEO Chris Schelling, CEO Biotechnology Becky Taub, CMO & EVP, R&D Laurence Cooper, MD, PhD, Armon Sharei, CEO CEO

10:30 AM Catalyst Pharmaceuticals, argenx SE (ARGX BB) Neurocrine Biosciences, Inc. Lantheus Holdings, Inc. Prothena Corporation plc Spring Bank Pharmaceuticals, Generation Bio Co. (Private) Inc. (CPRX) Biotechnology (NBIX) (LNTH) (PRTA) Inc. (SBPH) Biotechnology Pharmaceuticals Keith Woods, COO Biotechnology Life Sciences Biotechnology Biotechnology Geoff McDonough, CEO Patrick McEnany, Co-Founder, Kevin Gorman, CEO Mary Anne Heino, President & Gene Kinney, CEO; Martin Driscoll, CEO Chairman, CEO & President; CEO; Mark Kinarney, Director, Tran Nguyen, COO & CFO Steven Miller, COO & Chief IR Scientific Officer

11:00 AM Antares Pharma, Inc. (ATRS) Fagron NV (FAGR BB) Agilent Technologies Inc. (A) Fate Therapeutics, Inc. (FATE) Millendo Therapeutics, Inc. Osmotica Pharmaceuticals Schrodinger, LLC (Private) Pharmaceuticals Pharmaceuticals Life Sciences Biotechnology (MLND) plc (OSMT) Healthcare Services Bob Apple, President & CEO Rafael Padilla, CEO; Bob McMahon, CFO Scott Wolchko, CEO Biotechnology Pharmaceuticals Ramy Farid, President & CEO Constantijn van Rietschoten, Julia Owens, President & CEO Brian Markison, CEO; Andrew Chief Communications Officer Einhorn, CFO; James "JD" Schaub, COO

11:30 AM Progenics Pharmaceuticals, Laboratorios Farmaceuticos GlaxoSmithKline plc (GSK ArQule Inc. (ARQL) Liquidia Technologies, Inc. Erytech Pharma (ERYP/ERYP Pluristem Therapeutics, Inc. Inc. (PGNX) ROVI, S.A. (ROVI SM) LN) Biotechnology (LQDA) FP) (PSTI) Biotechnology Pharmaceuticals Pharmaceuticals Paolo Pucci, CEO; Biotechnology Biotechnology Biotechnology Mark Baker, CEO Juan López-Belmonte, CEO; Deborah Waterhouse, CEO of Peter Lawrence, President & Neal Fowler, CEO Gil Beyen, CEO O Yaky Yanay, Co-CEO & Javier López-Belmonte, CFO ViiV; David Redfern, Cheif COO President Strategy Officer

AGENDA THURSDAY, JUNE 6, 2019 Jefferies 2019 Global Healthcare Conference

12:15 PM Best of ASCO Panel Moderators: Biren Amin, Maury Raycroft & Mike Yee, Biotech Research Analysts, Jefferies Panelists: Charles Baum, President & CEO, Mirati Therapeutics, Inc. Robert Bazemore, President & CEO, Epizyme, Inc. Maria Fardis, President & CEO, Iovance Biotherapeutics, Inc.

1:30 PM Deciphera Pharmaceuticals, Sangamo Therapeutics, Inc. Recordati S.p.A. (REC IM) Orthofix Medical Inc. (OFIX) Arix Bioscience plc (ARIX LN) Selecta Biosciences, Inc. Foghorn Therapeutics Inc. Inc. (DCPH) (SGMO) Pharmaceuticals MedTech Biotechnology (SELB) (Private) Biotechnology Biotechnology Andrea Recordati, CEO; Brad Mason, President & CEO Joe Anderson, CEO Biotechnology Biotechnology Steve Hoerter, President & CEO Sandy Macrae, CEO Fritz Squindo, CFO Carsten Brunn, CEO Adrian Gottschalk, CEO

2:00 PM Alpine Immune Sciences, Inc. Mirati Therapeutics, Inc. Allergan plc (AGN) HLS Therapeutics Inc. Aptose Biosciences Inc. Phathom Pharmaceuticals Apexigen Inc. (Private) (ALPN) (MRTX) Pharmaceuticals (HLS CN) (APTO) (Private) Biotechnology Biotechnology Biotechnology William Meury, EVP & Chief Pharmaceuticals Biotechnology Pharmaceuticals Xiaodong Yang, CEO Mitch Gold, Chairman & CEO Charles Baum, President & Commercial Officer; Christine Greg Gubitz, CEO; Gilbert William Rice, Chairman, David Socks, CEO CEO Chiou, Director, IR; Manisha Godin, President & COO EO President & CEO; Greg Chow, Narasimhan, VP, IR & Strategic SVP & CFO Initiatives

2:30 PM Zealand Pharma A/S Codexis, Inc. (CDXS) Denali Therapeutics Inc. Prometic Life Sciences Inc LeMaitre Vascular, Inc. Kala Pharmaceuticals, Inc. Neos Therapeutics, Inc. (ZEAL DC) Life Sciences (DNLI) (PLI CN) (LMAT) (KALA) (NEOS) Biotechnology John Nicols, CEO Biotechnology Biotechnology MedTech Biotechnology Pharmaceuticals Emmanuel Dulac, CEO Ryan Watts, CEO Kenneth Galbraith, CEO JJ Pellegrino, CFO Mark Iwicki, Chairman & CEO Jerry McLaughlin, CEO

3:00 PM Eiger BioPharmaceuticals, eHealth, Inc. (EHTH) Catalent, Inc. (CTLT) MacroGenics, Inc. (MGNX) Recro Pharma, Inc. (REPH) Cue Biopharma, Inc. (CEU) RAPT Therapeutics (Private) Inc. (EIGR) Healthcare Services Healthcare Services Biotechnology Pharmaceuticals Biotechnology Biotechnology Biotechnology Derek Yung, CFO; Wetteny Joseph, CFO Scott Koenig, President & CEO Gerri Henwood, President & Daniel Passeri, President & CEO Brian Wong, CEO David Cory, President & CEO Kate Sidorovich, VP Finance & CEO IR EO

3:30 PM Puma Biotechnology, Inc. Varex Imaging Corporation Evotec SE (EVT GR) Clinuvel Pharmaceuticals BioLife Solutions, Inc. (BLFS) LogicBio Therapeutics, Inc. Pieris Pharmaceuticals, Inc. (PBYI) (VREX) Healthcare Services Limited (CUV AU) Life Sciences (LOGC) (PIRS) Biotechnology MedTech Werner Lanthaler, CEO Biotechnology Mike Rice, CEO Biotechnology Biotechnology Alan Auerbach, CEO, President Sunny Sanyal, CEO; Philippe Wolgen, CEO Fred Chereau, President & CEO Stephen Yoder, CEO; & Chairman Clarence Verhoef, CFO Allan Reine, CFO

4:00 PM Adaptimmune Therapeutics PTC Therapeutics, Inc. Bruker Corporation (BRKR) KalVista Pharmaceuticals, Evelo Biosciences, Inc. Tocagen Inc. (TOCA) NexImmune, Inc. (Private) plc (ADAP) (PTCT) Life Sciences Inc. (KALV) (EVLO) Biotechnology Biotechnology Biotechnology Biotechnology Frank Laukien, CEO Biotechnology Biotechnology Marty Duvall, CEO Scott Carmer, CEO Adrian Rawcliffe, CFO; Stuart Peltz, CEO Andy Crockett, CEO; Simba Gill, CEO; Jonathan Rafael Amado, President, Ben Palleiko, CBO & CFO; Poole, CFO Research IR Development; Chris Yea, Chief Development Sébastien Desprez, VP, Comm Officer & IR

4:30 PM Unity Biotechnology, Inc. Rhythm Pharmaceuticals, Akcea Therapeutics, Inc. Bavarian Nordic A/S Nabriva Therapeutics plc Ocular Therapeutix, Inc. Prota Therapeutics Pty Ltd (UBX) Inc. (RYTM) (AKCA) (BAVA DC) (NBRV) (OCUL) (Private) Biotechnology Biotechnology Biotechnology Biotechnology Biotechnology Biotechnology Biotechnology Bob Goeltz, CFO Keith Gottesdiener, CEO Paula Soteropoulos, CEO Paul Chaplin, President & CEO Ted Schroeder, CEO Antony Mattessich, President & Wade King, M.D., CEO; CEO Mimi Tang, M.D., Founder, CSO & CMO

AGENDA FRIDAY, JUNE 7, 2019 Jefferies 2019 Global Healthcare Conference

8:00 AM AIT Therapeutics, Inc. (AITB) Alphatec Holdings, Inc. Amicus Therapeutics, Inc. Seelos Therapeutics, Inc. Goldfinch Biopharma Inc. Genevant Sciences Corp Pharmaceuticals (ATEC) (FOLD) (SEEL) (Private) (Private) Steve Lisi, CEO MedTech Biotechnology Pharmaceuticals Biotechnology Pharmaceuticals Pat Miles, CEO; Jeff Black, CFO Daphne Quimi, CFO Raj Mehra, CEO Tony Johnson, CEO Jens Bo Rode Hansen, CEO

8:30 AM Pear Therapeutics (Private) scPharmaceuticals Inc. Processa Pharmaceuticals, Caris Life Sciences, Inc. Compass Therapeutics LLC MedTech (SCPH) Inc. (PCSA) (Private) (Private) Corey McCann, President & Pharmaceuticals Pharmaceuticals Biotechnology Biotechnology CEO John Tucker, President & CEO David Young, CEO; Patrick Lin, Brian Brille, Vice Chairman Thomas Schuetz, Co-Founder Chief Business & Strategy & CEO Officer

9:00 AM EIP Pharma, LLC (Private) BeyondSpring Inc. (BYSI) PT Kalbe Farma Tbk (KLBF IJ) BioXcel Therapeutics, Inc. Torque Therapeutics, Inc. Incysus Therapeutics, Inc. Grace Therapeutics Inc. Biotechnology Biotechnology Pharmaceuticals (BTAI) (Private) (Private) (Private) John Alam, President & CEO Edward Liu, CFO TBD Biotechnology Biotechnology Biotechnology Biotechnology Vimal Mehta, CEO; Richard Bart Henderson, CEO William Ho, President & CEO Bruce Hochstadt, COO Steinhart, CFO; Frank Yocca, CSO; Vince O'Neil, SVP & CMO

9:30 AM Akorn, Inc. (AKRX) DBV Technologies S.A. AnaptysBio, Inc. (ANAB) Immunovia AB (IMMNOV) Marinus Pharmaceuticals, Corvidia Therapeutics, Inc. Pharmaceuticals (DBVT) Biotechnology Life Sciences Inc. (MRNS) (Private) Doug Boothe, President & Biotechnology Hamza Suria, President & CEO; Mats Grahn, CEO Biotechnology Biotechnology CEO; Duane Portwood, CFO; Kevin Trapp, Chief Dominic Piscitelli, CFO Ed Smith, CFO; Marc de Garidel, CEO; Ram Jennifer Bowles, SVP Corp Commercial Officer Lisa Caperelli, EVP & CFO Aiyar, EVP BD Strategy & IR

10:00 AM Calyxt, Inc. (CLXT) Luye Pharma Group Ltd. Elekta AB (EKTAB SS) Precision BioSciences, Inc. Synaptive Medical Inc. Oncoceutics, Inc. (Private) Biotechnology (2186 HK) MedTech (DTIL) (Private) Pharmaceuticals Jim Blome, CEO Pharmaceuticals Gustaf Salford, CFO Biotechnology MedTech Lee Schalop, COO Sammy Jiang, VP Matt Kane, CEO Cameron Piron, President & Chief Strategy Officer

10:30 AM Kodiak Sciences Inc. (KOD) CStone Pharmaceuticals Alnylam Pharmaceuticals, Pharming Group N.V. Aldeyra Therapeutics, Inc. Adicet Bio, Inc. (Private) CANbridge Pharmaceuticals Biotechnology (2616 HK) Inc. (ALNY) (PHARM BQ) (ALDX) Biotechnology INC (Private) Victor Perlroth, CEO Biotechnology Biotechnology Biotechnology Biotechnology Anil Singhal, Ph.D., President Pharmaceuticals Richard Yeh, CFO Barry Greene, President; James Cornicelli, VP, Global Todd Brady, President & CEO & CEO James Xue, Founder, Chairman Manmeet Soni, CFO Business Development & CEO

11:00 AM Alphamab Oncology Axovant Gene Therapies Ping An Healthcare and Ark Biosciences Inc. (Private) Marker Therapeutics, Inc. (Private) (AXGT) Technology Company Biotechnology (MRKR) Biotechnology Biotechnology Limited (1833 H1) James Wu, CEO Biotechnology Ting Xu, CEO & Founder; Pavan Cheruvu, CEO Healthcare Services Peter Hoang, President & CEO Terry Shuai, CFO; Mike Liu, Yin Fan, Managing Directorv SVP, Business Development 11:30 AM Rafael Pharmaceuticals, Inc. Oncopeptides AB (ONCO Cronos Group Inc. (7CI GR) Verastem, Inc. (VSTM) Forbius (Private) (Private) SS) Cannabis Biotechnology Biotechnology Pharmaceuticals Biotechnology Michael Gorenstein, President, Robert Forrester, President & Ilia Tikhomirov, CEO Sanjeev Luther, President & Jakob Lindberg, CEO CEO & Chairman CEO CEO

AGENDA FRIDAY, JUNE 7, 2019 Jefferies 2019 Global Healthcare Conference

BALLROOM 1 BALLROOM 2 BALLROOM 3 BALLROOM 4 BALLROOM 5 BREAKOUT: URIS BREAKOUT: JUILLIARD BREAKOUT: BROADWAY BREAKOUT: CARNEGIE HALL BREAKOUT: ALVIN 12:00 PM Break for Lunch / Presentation Room Setup

12:30 PM Neon Therapeutics, Inc. (NTGN) Aurinia Pharmaceuticals Inc. (AUPH) Genscript Biotech Corporation (1548 HK) Zymeworks Inc. (ZYME) Antengene Corporation (Private) Biotechnology Biotechnology Life Sciences Biotechnology Pharmaceuticals Hugh O'Dowd, CEO Peter Greenleaf, CEO TBD Ali Tehrani, Ph.D., CEO TBD

1:00 PM Enlivex Therapeutics Ltd. (ENLV) MEI Pharma, Inc. (MEIP) Cantel Medical Corp. (CMD) Newron Pharmaceuticals S.p.A. Inventiva S.A. (IVA FP) Biotechnology Biotechnology MedTech (NWRN SW) Biotechnology Shmulik Hess, CEO Dan Gold, Ph.D., CEO Peter Clifford, EVP & CFO Biotechnology Frederic Cren, CEO Stefan Weber, CEO

1:30 PM Welwaze Medical Inc. (Private) Nanobiotix SA (NANO FP) ALK-Abelló A/S (ALKB DC) MedTech Biotechnology Pharmaceuticals TBD Laurent Levy, CEO Søren Jelert, CFO & EVP

2:00 PM ClearDATA Networks, Inc. (Private) MediGene AG (MDG1 GR) Cellectis S.A. (CLLS) ImmusanT, Inc. (Private) TriNetX, Inc. (Private) MedTech Biotechnology Biotechnology Pharmaceuticals MedTech Darin Brannan, CEO Dolores Schendel, CEO & CSO Andre Choulika, Chairman & CEO; Leslie Williams, CEO Gadi Lachman, CEO & President Simon Harnest, VP Strategy & Finance

2:30 PM Immunocore Limited (Private) Tyme Technologies, Inc. (TYME) RadNet, Inc. (RDNT) TRACON Pharmaceuticals, Inc. (TCON) Biotechnology Biotechnology Healthcare Services Biotechnology Bahija Jallal, CEO; David Berman, Head of Ben Taylor, President & CFO Howard Berger, Chairman & CEO Charles Theuer, CEO Research & Development