B-Nitrox Systems the Safe and Secure Solution for Producing and Compressing Nitrox
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Is Colonic Propionate Delivery a Novel Solution to Improve Metabolism and Inflammation in Overweight Or Obese Subjects?
Commentary in IgG levels in IPE-treated subjects versus Is colonic propionate delivery a novel those receiving cellulose supplementa- tion. This interesting discovery is the Gut: first published as 10.1136/gutjnl-2019-318776 on 26 April 2019. Downloaded from solution to improve metabolism and first evidence in humans that promoting the delivery of propionate in the colon inflammation in overweight or may affect adaptive immunity. It is worth noting that previous preclinical and clin- obese subjects? ical data have shown that supplementation with inulin-type fructans was associated 1,2 with a lower inflammatory tone and a Patrice D Cani reinforcement of the gut barrier.7 8 Never- theless, it remains unknown if these effects Increased intake of dietary fibre has been was the lack of evidence that the observed are directly linked with the production of linked to beneficial impacts on health for effects were due to the presence of inulin propionate, changes in the proportion of decades. Strikingly, the exact mechanisms itself on IPE or the delivery of propionate the overall levels of SCFAs, or the pres- of action are not yet fully understood. into the colon. ence of any other bacterial metabolites. Among the different families of fibres, In GUT, Chambers and colleagues Alongside the changes in the levels prebiotics have gained attention mainly addressed this gap of knowledge and of SCFAs, plasma metabolome analysis because of their capacity to selectively expanded on their previous findings.6 For revealed that each of the supplementa- modulate the gut microbiota composition 42 days, they investigated the impact of tion periods was correlated with different 1 and promote health benefits. -
Development of the Crew Dragon ECLSS
ICES-2020-333 Development of the Crew Dragon ECLSS Jason Silverman1, Andrew Irby2, and Theodore Agerton3 Space Exploration Technologies, Hawthorne, California, 90250 SpaceX designed the Crew Dragon spacecraft to be the safest ever flown and to restore the ability of the United States to launch astronauts. One of the key systems required for human flight is the Environmental Control and Life Support System (ECLSS), which was designed to work in concert with the spacesuit and spacecraft. The tight coupling of many subsystems combined with an emphasis on simplicity and fault tolerance created unique challenges and opportunities for the design team. During the development of the crew ECLSS, the Dragon 1 cargo spacecraft flew with a simple ECLSS for animals, providing an opportunity for technology development and the early characterization of system-level behavior. As the ECLSS design matured a series of tests were conducted, including with humans in a prototype capsule in November 2016, the Demo-1 test flight to the ISS in March 2019, and human-in-the-loop ground testing in the Demo-2 capsule in January 2020 before the same vehicle performs a crewed test flight. This paper describes the design and operations of the ECLSS, the development process, and the lessons learned. Nomenclature AC = air conditioning AQM = air quality monitor AVV = active vent valve CCiCap = Commercial Crew Integrated Capability CCtCap = Commercial Crew Transportation Capability CFD = computational fluid dynamics conops = concept of operations COPV = composite overwrapped -
The Lower Critical Solution Temperature (LCST) Transition
Copyright by David Samuel Simmons 2009 The Dissertation Committee for David Samuel Simmons certifies that this is the approved version of the following dissertation: Phase and Conformational Behavior of LCST-Driven Stimuli Responsive Polymers Committee: ______________________________ Isaac Sanchez, Supervisor ______________________________ Nicholas Peppas ______________________________ Krishnendu Roy ______________________________ Venkat Ganesan ______________________________ Thomas Truskett Phase and Conformational Behavior of LCST-Driven Stimuli Responsive Polymers by David Samuel Simmons, B.S. Dissertation Presented to the Faculty of the Graduate School of The University of Texas at Austin in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy The University of Texas at Austin December, 2009 To my grandfather, who made me an engineer before I knew the word and to my wife, Carey, for being my partner on my good days and bad. Acknowledgements I am extraordinarily fortunate in the support I have received on the path to this accomplishment. My adviser, Dr. Isaac Sanchez, has made this publication possible with his advice, support, and willingness to field my ideas at random times in the afternoon; he has my deep appreciation for his outstanding guidance. My thanks also go to the members of my Ph.D. committee for their valuable feedback in improving my research and exploring new directions. I am likewise grateful to the other members of Dr. Sanchez’ research group – Xiaoyan Wang, Yingying Jiang, Xiaochu Wang, and Frank Willmore – who have shared their ideas and provided valuable sounding boards for my mine. I would particularly like to express appreciation for Frank’s donation of his own post-graduation time in assisting my research. -
Exercise and Cellular Respiration Lab
California State University of Bakersfield, Department of Chemistry Exercise and Cellular Respiration Lab Standards: MS-LS1-7 Develop a model to describe how food is rearranged through chemical reactions forming new molecules that support growth and/or release energy as this matter moves through an organism. Introduction: I. Background Information. Cellular respiration (see chemical reaction below) is a chemical reaction that occurs in your cells to create energy; when you are exercising your muscle cells are creating ATP to contract. Cellular respiration requires oxygen (which is breathed in) and creates carbon dioxide (which is breathed out). This lab will address how exercise (increased muscle activity) affects the rate of cellular respiration. You will measure 3 different indicators of cellular respiration: breathing rate, heart rate, and carbon dioxide production. You will measure these indicators at rest (with no exercise) and after 1 and 2 minutes of exercise. Breathing rate is measured in breaths per minute, heart rate in beats per minute, and carbon dioxide in the time it takes bromothymol blue to change color. Carbon dioxide production can be measured by breathing through a straw into a solution of bromothymol blue (BTB). BTB is an acid indicator; when it reacts with acid it turns from blue to yellow. When carbon dioxide reacts with water, a weak acid (carbonic acid) is formed (see chemical reaction below). The more carbon dioxide you breathe into the BTB solution, the faster it will change color to yellow. The purpose of this lab activity is to analyze the effect of exercise on cellular respiration. Background: I. -
Code of Federal Regulations GPO Access
4±23±97 Wednesday Vol. 62 No. 78 April 23, 1997 Pages 19667±19896 Briefings on how to use the Federal Register For information on briefings in Washington, DC, see announcement on the inside cover of this issue. Now Available Online Code of Federal Regulations via GPO Access (Selected Volumes) Free, easy, online access to selected Code of Federal Regulations (CFR) volumes is now available via GPO Access, a service of the United States Government Printing Office (GPO). CFR titles will be added to GPO Access incrementally throughout calendar years 1996 and 1997 until a complete set is available. GPO is taking steps so that the online and printed versions of the CFR will be released concurrently. The CFR and Federal Register on GPO Access, are the official online editions authorized by the Administrative Committee of the Federal Register. New titles and/or volumes will be added to this online service as they become available. http://www.access.gpo.gov/nara/cfr For additional information on GPO Access products, services and access methods, see page II or contact the GPO Access User Support Team via: ★ Phone: toll-free: 1-888-293-6498 ★ Email: [email protected] federal register 1 II Federal Register / Vol. 62, No. 78 / Wednesday, April 23, 1997 SUBSCRIPTIONS AND COPIES PUBLIC Subscriptions: Paper or fiche 202±512±1800 Assistance with public subscriptions 512±1806 General online information 202±512±1530; 1±888±293±6498 FEDERAL REGISTER Published daily, Monday through Friday, Single copies/back copies: (not published on Saturdays, Sundays, or on official holidays), by the Office of the Federal Register, National Archives and Paper or fiche 512±1800 Records Administration, Washington, DC 20408, under the Federal Assistance with public single copies 512±1803 Register Act (49 Stat. -
Leonardo User Manual
Direction for use Computer Leonardo ENGLISH cressi.com 2 TABLE OF CONTENTS Main specifications page 4 TIME SET mode: General recommendations Date and time adjustment page 31 and safety measures page 5 SYSTEM mode: Introduction page 10 Setting of measurement unit and reset page 31 1 - COMPUTER CONTROL 3 - WHILE DIVING: COMPUTER Operation of the Leonardo computer page 13 FUNCTIONS 2 - BEFORE DIVING Diving within no decompression limits page 36 DIVE SET mode: DIVE AIR function: Setting of dive parameters page 16 Dive with Air page 37 Oxygen partial pressure (PO2) page 16 DIVE NITROX function: Nitrox - Percentage of the oxygen (FO2) page 18 Dive with Nitrox page 37 Dive Safety Factor (SF) page 22 Before a Nitrox dive page 37 Deep Stop page 22 Diving with Nitrox page 40 Altitude page 23 CNS toxicity display page 40 PLAN mode: PO2 alarm page 43 Dive planning page 27 Ascent rate page 45 GAGE mode: Safety Stop page 45 Depth gauge and timer page 27 Decompression forewarning page 46 Deep Stop page 46 3 Diving outside no decompression limits page 50 5 - CARE AND MAINTENANCE Omitted Decompression stage alarm page 51 Battery replacement page 71 GAGE MODE depth gauge and timer) page 52 6 - TECHNICAL SPECIFICATIONS Use of the computer with 7 - WARRANTY poor visibility page 56 4 - ON SURFACE AFTER DIVING Data display and management page 59 Surface interval page 59 PLAN function - Dive plan page 60 LOG BOOK function - Dive log page 61 HISTORY function - Dive history page 65 DIVE PROFILE function - Dive profile page 65 PCLINK function Pc compatible interface page 66 System Reset Reset of the instrument page 70 4 Congratulations on your purchase of your Leo - trox) dive. -
Special Operations Rebreathers
Special Operations Underwater Life Support Systems INTRODUCTION TO JFD JFD is the world leading underwater capability provider facilitating the commercial and defence diving industries by offering innovative diving, submarine rescue and subsea technical solutions. JFD has a well-established history in the development of advanced and innovative diving and submarine rescue systems spanning over 30 years. Our systems continue to set the president in terms of capability and performance and JFD is relied upon by divers worldwide across both the defence and commercial sectors. Our products and services have been delivered to a large number of countries across all continents. With in-service support established in many of these locations and tailored Integrated Logistics Support (ILS) packages, JFD is able to provide high customer equipment availability, rapid technical support and tailored training packages. 2 | Introduction JFD offers two highly capable underwater life support systems to meet the full mission profile of today’s Special Operations diver. A modular approach enables customisation of the life support system in response to demands across the full operational spectrum. SHADOW ENFORCER The solution for extended duration and deeper diving The lightweight solution for short duration mission mission profiles. profiles. 3 | Offering A common life support platform facilitates a multi-mission capability offering numerous operational and logistic benefits that include: ENHANCED MISSION EFFECTIVENESS • Front and back mount options • Oxygen -
Brownie's THIRD LUNG
BrMARINEownie GROUP’s Owner’s Manual Variable Speed Hand Carry Hookah Diving System ADVENTURE IS ALWAYS ON THE LINE! VSHCDC Systems This manual is also available online 3001 NW 25th Avenue, Pompano Beach, FL 33069 USA Ph +1.954.462.5570 Fx +1.954.462.6115 www.BrowniesMarineGroup.com CONGRATULATIONS ON YOUR PURCHASE OF A BROWNIE’S SYSTEM You now have in your possession the finest, most reliable, surface supplied breathing air system available. The operation is designed with your safety and convenience in mind, and by carefully reading this brief manual you can be assured of many hours of trouble-free enjoyment. READ ALL SAFETY RULES AND OPERATING INSTRUCTIONS CONTAINED IN THIS MANUAL AND FOLLOW THEM WITH EACH USE OF THIS PRODUCT. MANUAL SAFETY NOTICES Important instructions concerning the endangerment of personnel, technical safety or operator safety will be specially emphasized in this manual by placing the information in the following types of safety notices. DANGER DANGER INDICATES AN IMMINENTLY HAZARDOUS SITUATION WHICH, IF NOT AVOIDED, WILL RESULT IN DEATH OR SERIOUS INJURY. THIS IS LIMITED TO THE MOST EXTREME SITUATIONS. WARNING WARNING INDICATES A POTENTIALLY HAZARDOUS SITUATION WHICH, IF NOT AVOIDED, COULD RESULT IN DEATH OR INJURY. CAUTION CAUTION INDICATES A POTENTIALLY HAZARDOUS SITUATION WHICH, IF NOT AVOIDED, MAY RESULT IN MINOR OR MODERATE INJURY. IT MAY ALSO BE USED TO ALERT AGAINST UNSAFE PRACTICES. NOTE NOTE ADVISE OF TECHNICAL REQUIREMENTS THAT REQUIRE PARTICULAR ATTENTION BY THE OPERATOR OR THE MAINTENANCE TECHNICIAN FOR PROPER MAINTENANCE AND UTILIZATION OF THE EQUIPMENT. REGISTER YOUR PRODUCT ONLINE Go to www.BrowniesMarineGroup.com to register your product. -
Nitrox Recreational Mode - Perdix
Nitrox Recreational Mode - Perdix User Manual Shearwater Perdix Nitrox Recreational Mode 8. System Setup+ ...........................................................18 Table of Contents 8�1� Dive Setup ��������������������������������������������������������������������������������������������������������� 18 Mode �������������������������������������������������������������������������������������������������������� 18 Table of Contents �����������������������������������������������������������������������������������������������������2 Salinity ����������������������������������������������������������������������������������������������������� 18 Conventions Used in this Manual �����������������������������������������������������������������������3 8�2� Deco Setup ������������������������������������������������������������������������������������������������������� 19 1. Introduction .................................................................. 4 Conservatism ������������������������������������������������������������������������������������������� 19 1�1� Features ���������������������������������������������������������������������������������������������������������������4 Safety Stop ���������������������������������������������������������������������������������������������� 19 8�3� Bottom Row ����������������������������������������������������������������������������������������������������� 19 2. Modes Covered by this Manual ................................. 5 8�4� Nitrox Gases ���������������������������������������������������������������������������������������������������� -
Affinity of Small-Molecule Solutes to Hydrophobic, Hydrophilic, and Chemically Patterned Interfaces in Aqueous Solution
Affinity of small-molecule solutes to hydrophobic, hydrophilic, and chemically patterned interfaces in aqueous solution Jacob I. Monroea, Sally Jiaoa, R. Justin Davisb, Dennis Robinson Browna, Lynn E. Katzb, and M. Scott Shella,1 aDepartment of Chemical Engineering, University of California, Santa Barbara, CA 93106; and bDepartment of Civil, Architectural and Environmental Engineering, University of Texas at Austin, Austin, TX 78712 Edited by Peter J. Rossky, Rice University, Houston, TX, and approved November 17, 2020 (received for review September 30, 2020) Performance of membranes for water purification is highly influ- However, a molecular understanding that links membrane enced by the interactions of solvated species with membrane surface chemistry to solute affinity and hence membrane func- surfaces, including surface adsorption of solutes upon fouling. tional properties remains incomplete, due in part to the complex Current efforts toward fouling-resistant membranes often pursue interplay among specific interactions (e.g., hydrogen bonds, surface hydrophilization, frequently motivated by macroscopic electrostatics, dispersion) and molecular morphology (e.g., sur- measures of hydrophilicity, because hydrophobicity is thought to face and polymer configurations) that are difficult to disentangle increase solute–surface affinity. While this heuristic has driven di- (11–14). Chemically heterogeneous surfaces are even less un- verse membrane functionalization strategies, here we build on derstood but can affect fouling in complex ways. -
The Implications of SCUBA Diving with Air Vs. Enriched-Air Nitrox on Mental and Physical Fatigue
The Implications of SCUBA diving with Air vs. Enriched-Air Nitrox on Mental and Physical Fatigue. Introduction SCUBA (Self-Contained Underwater Breathing Apparatus) diving is commonly done using tanks filled with compressed ambient air containing 21% oxygen, 78% nitrogen, and 1% miscellaneous gases. When not SCUBA diving, nitrogen passes harmlessly through a person’s blood stream. When nitrogen is inhaled at depth, the higher pressure causes more nitrogen to diffuse into the blood stream and various body tissues. Then, after returning to lower pressure at the surface, nitrogen gas dissolved in tissues diffuses and forms bubbles in the bloodstream, which eventually off gas and escape the body through normal exhalation or, in extreme cases, can expand to block blood flow or burst the vessel (1). The blockages or bursts result in symptoms like joint or muscular pain, headaches, dizziness, fatigue, and many others. This serious medical issue is known as decompression sickness (DCS). The formation of nitrogen bubbles in the bloodstream, along with other factors, is thought to induce fatigue. By decreasing the amount of nitrogen absorbed, divers could possibly experience less fatigue and reduce the likelihood of DCS (2). The most common way to achieve this is enriched-air nitrox (EAN) diving where a diver uses a gas mixture that has an increased oxygen composition and decreased nitrogen composition. While many experienced SCUBA divers claim that EAN diving reduces post-dive fatigue, the few studies testing the impact of breathing EAN on post-dive fatigue either did not document an effort to hide the gas composition from the subjects, which would allow for a placebo effect, (3) or the study Emma Z SCUBAnauts International, Tampa Chapter 2019 conducted dry dives using a compression chamber which removes contributing factors like temperature and physical exertion felt on an actual dive (4). -
The Hydrophobic Effect Oil and Water Do Not Mix. This Fact Is So Well
The hydrophobic effect Oil and water do not mix. This fact is so well engrained in our ever-day experience that we never ask “why”. Well, today we are going to ask just this question: “why do oil and water not mix?” At the end of the class you will hopefully see that the reason oil and water do not mix is quite distinct from the reason many other substance do not mix. You will also see that the hydrophobic effect is part of a family of processes called “entropy driven ordering” and that the hydrophobic effect has nothing to do with bonds between hydrophobic molecules. This should sound a bit strange to you right now, but I am sure that at the end of the class it will all make sense to you. Why most liquids mix or do not mix (the generic case) What would our physico-chemical intuition tell us about the process of mixing two liquids? Lets think of a simple lattice model for the two solutions. If we call the substances A and B, the energy for mixing should then be the energy of interaction that are made between A and B, minus the energy of interactions that A made with A, and B made with B, plus the entropy of mixing. "Gmixing = "Hmixing # T"Smixing where "Hmixing = 2"Ha#b # "Ha#a # "Hb#b What predictions would this simple model for solutions make for the energetics of mixing? First, mixing should be favored by entropy and therefore the tendency to mix ! should increase with temperature.