DOCSLIB.ORG

4-Year-Old Collie Mix Female Dog with Bilateral, Non-Symmetric Alopecia, Scarring and Hypopigmentation on the Dorsum of the Nose

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
4-Year-Old Collie Mix Female Dog with Bilateral, Non-Symmetric Alopecia, Scarring and Hypopigmentation on the Dorsum of the Nose 4-year-old collie mix female dog with bilateral, non-symmetric alopecia, scarring and hypopigmentation on the dorsum of the nose. Which of the following is the most likely disease? 1. Systemic lupus erythematosus 2. Thermal burn 3. Pemphigus foliaceus 4. Erythema multiforme 5. Ischemic dermatopathy CORRECT Signalment and history: A 4-year-old collie mix female dog was examined for 2.5-year duration of a bilateral, non-symmetric alopecic lesion with scarring and hypopigmentation on the dorsal skin of the nose (Figure 1). The lesion involves the nasal planum where it is associated with multifocal erosions; exfoliative and erosive lesions are also present on the footpad and cicatritial and alopecic lesions are present on the tip of the ears. The dogs is also affected by an eosinophilic colitis and it is under a hypoallergenic diet. Histopathologic description: The histopathological examination of the biopsy from the dorsum of the nose revealed the presence of a severe and diffuse follicular atrophy with a lesser involvement of the sebaceous glands. Dermal collagen appears to be rarefied and pale eosinophilic and homogeneous (Figure 2 and 3). Multifocal degeneration of basal keratinocytes is also observed, sometimes responsible for artefactual detachment at epidermal dermoepidermal junction. In the basal cell layer are multifocal apoptotic cells and the dermo-epidermal interface is obscured by a cell-poor infiltrate consisting of lymphocytes, histiocytes and rare mast cells, plasma cells and neutrophils. Small caliber vessels in the superficial dermis sometimes have hypereosynophilic walls without endothelial cell lining (Figure 4). In the superficial dermis pigment incontinence is observed in association with a lymphocytic and histiocytic mural folliculitis. In some areas there is a periadnexal lymphocytic infiltrate with multifocal deep extension and involvement of muscle fibers causing myositis (Figure 5). Morphologic diagnosis: "Cell-poor" lymphocytic interface dermatitis and folliculitis with follicular atrophy, vasculopathy (cell poor vasculitis) and myositis. Name the condition: Ischemic dermatopathy – Dermatomyositis (d.d. Dermatomyositis-like disease). Comment: The histopathological lesions in the biopsy examined are suggestive of an ischemic dermatopathy which, for the breed reported (collie mixed) and for the early age onset, are compatible with a canine familial dermatomyositis (dd ischemic dermatopathy with early onset and no breed predisposition, dermatomyositis-like disease). Canine familial dermatomyositis is an uncommon hereditary disease of collies, Shetland sheepdogs, Beauceron shepherds, Belgian Tervurens and Portuguese water dogs. A similar disease, called dermatomyositis-like disease, has been described in the Pembroke Welsh corgi, Lakeland terrier, chow chow, Jack Russell terrier, German shepherd dog, Kuvasz, Rottweiler and in mongrels and has been recognized in other purebred dogs. The disease is characterized by skin lesions and generalized myositis, with early onset between 7 weeks and 6 months of age. The skin lesions are located on the face, ears, lips, tail tip, and bony prominences of the distal legs. In the early phase, there is erythema, scaling, crusting, and ulceration. Chronically affected dogs develop alopecia and scarring, with hyper- or hypopigmentation. Myositis usually affects the masticatory muscles and muscles of the extremities below the elbow and stifle. Although muscle lesions are rare, when present, they can be the most severe clinical presentation of dermatomyositis. Severely affected dogs may have generalized myositis and develop megaesophagus. The cause of the disease is poorly understood. Elevated serum complement levels and class G immunoglobulins have been demonstrated, therefore a genetically determined immune-mediated pathogenesis is suspected. Inheritance studies of dermatomyositis in the collie suggest that it may be an autosomal dominant trait with incomplete penetrance. In Shetland Sheepdog, the locus affecting the dermatomyositis phenotype seems to be located near marker FH3570 in chromosome 35. A gene expression profile study investigating affected and normal skin of dogs with dermatomyositis demonstrated a differential regulation of 285 genes and an absence of disease-specific autoantibodies in dermatomyositis affected dogs. A very recent study, through whole genome resequencing, identified primary candidate polymorphisms in conserved regions of PAN2 and MAP3K7CL on chromosomes 10 and 31, respectively, in Collies and Shetland Sheepdogs. These two loci, in association with MHC haplotypes, were associated with an increased risk of disease development. Histological examination demonstrates a cell-poor lymphocytic or lympho-histiocytic interface dermatitis and folliculitis with hydropic degeneration and apoptosis of basal keratinocytes. The dermis is homogenous and pale and hair follicles are atrophic. Blood vessel show features of cell-poor vasculopathy. All these changes were grouped together by Gross TL et all. under the term ‘ischaemic dermatopathy’. This histological pattern is common to several different clinical pictures: 1. canine familial dermatomyositis; 2. juvenile-onset ischemic dermatopathy with no breed predilection (dermatomyositis-like disease); 3. postrabies vaccination panniculitis; 4. generalized vaccine-induced ischaemic dermatopathy; and 5. adult-onset (nonvaccine-induced) generalized ischaemic dermatopathy (“generalized idiopathic ischemic dermatopathy”). The present case and the concurrent presence of histologic evidence of myositis, in association with the breed (collie mix), is suggestive of a canine familial dermatomyositis. However, as information on the hereditability and familiarity of skin lesions in this animal are unknown, a dermatomyositis-like disease has to be considered as a differential diagnosis. References: Bresciani F, Zagnoli L, Fracassi F, Bianchi E, Cantile C, Abramo F, Pietra M. Dermatomyositis-like disease in a Rottweiler. Vet Dermatol. 2014 Jun;25(3):229-32, e61-2. Clark LA, Credille KM, Murphy KE, Rees CA. Linkage of dermatomyositis in the Shetland Sheepdog to chromosome 35. Vet Dermatol. 2005 Dec;16(6):392-4. Evans JM, Noorai RE, Tsai KL, Starr-Moss AN, Hill CM, Anderson KJ, Famula TR, Clark LA. Beyond the MHC: A canine model of dermatomyositis shows a complex pattern of genetic risk involving novel loci. PLoS Genet. 2017 Feb 3;13(2):e1006604. Ferguson EA, Cerundolo R, Lloyd DH, Rest J, Cappello R. Dermatomyositis in five Shetland sheepdogs in the United Kingdom. Vet Rec. 2000 Feb 19;146(8):214-7. Gross TL, Ihrke PJ, Walder EJ, Affolter VK. Interface diseases of the dermal-epidermal junction. In: Skin Diseases of the Dog and Cat, Clinical and Histopathological Diagnosis. 2nd Ed, Ames, IA: Blackwell, 2005: 49- 52. Miller WH, Griffin CE, Campbell KL. In: Muller & Kirk’s Small Animal Dermatology, 7th Ed, Elsevier, 2013: 585-587. Morris DO. Ischemic dermatopathies. Vet Clin North Am Small Anim Pract. 2013 Jan;43(1):99-111. Nuttall TJ. What is your diagnosis? Dermatomyositis. J Small Anim Pract. 1998 Jul;39(7):317, 356. Wahl JM, Clark LA, Skalli O, Ambrus A, Rees CA, Mansell JL, Murphy KE. Analysis of gene transcript profiling and immunobiology in Shetland sheepdogs with dermatomyositis. Vet Dermatol. 2008 Apr;19(2):52-8. Yoon JS, Minami T, Takizawa Y, Sekiguchi M, Yabuzoe A, Ide K, Nishifuji K, Iwasaki T. Two dogs with juvenile- onset skin diseases with involvement of extremities. J Vet Med Sci. 2010 Nov;72(11):1513-6. Contributors: Clinical case: Dr. Luca Luciani, Dermatologist, Cattolica (RN), Italy; Histopathology: Chiara Brachelente, Department of Veterinary Medicine, University of Perugia (PG), Italy. Figure legend: Figure 1: 4-year-old collie mix female dog. Bilateral, non-symmetric alopecia with scarring and hypopigmentation on the dorsal skin of the nose with involvement and multifocal erosions of the nasal planum. Figure 2. 4-year-old collie mix female dog. Diffuse and moderate to severe follicular atrophy with homogeneization and pallor of dermal collagen. Figure 3. 4-year-old collie mix female dog. Sever follicular atrophy with increased prominence of perifollicular connective tissue and multifocal periadnexal lymphocytic infiltration. Figure 4. 4-year-old collie mix female dog. Obscuration of the dermal-epidermal junction by a cell-poor lymphocytic infiltration, with basal cell degeneration and apoptosis. There is loss of endothelial cells and mummification of vessel walls in superficial dermal vessels (insert). Figure 5. 4-year-old collie mix female dog. In the deep portion of the biopsy there are perimysial lymphocytic and histiocytic infiltrations associated with myocyte fiber degeneration and phagocytosis. .
Load more

Recommended publications
  • The Beauceron
    The Beauceron The Beauceron, also known as Berger de Beauce and Bas Rouge, is the largest of the French sheepdogs and was developed solely in France with no foreign crosses. The Beauceron is closely related to the longhaired Briard or Berger de Brie. The first mention of a dog which matches the Beauceron’s description is found in a manuscript dated 1587. In 1809 Abbé Rozier wrote an article on French herding dogs. It was he who first described the differences in type and used the terms Berger de la Brie for long coated dogs and Berger de la Beauce for short coated dogs. The name Beauceron was used for the first time by Pierre Megnin in his 1888 book on war dogs and the first Berger de Beauce was registered with the Societe Central Canine in September 1893. The French Club Les Amis du Beauceron (CAB), was founded in 1922 by Pierre Megnin and he together with Emmanuel Boulet developed the original breed standard for the Beauceron. The CAB has since guided the development of the breed in its native France, always keeping a watchful eye on the preservation of the breed’s herding and working ability. During the early part of the 19th century large flocks of sheep were common and the Beauceron was indispensable for the shepherds of France; two dogs were sufficient to tend to flocks of 200 to 300 head of sheep. Sheep production experienced a sharp decline during the later half of the 19th century and by the second half of the 20th century was only a phantom of its past.
    [Show full text]
  • Frequently Asked Questions
    APPLYING SHAMPOO & CONDITIONER For best results apply the shampoo & conditioner in the following order: 1. belly & Determine the appropriate shampoo & conditioner for your breed. chest 2. legs and feet 3. neck & face 4. back SHORT COATS need LEMON, MEDIUM COATS need BANANA and bottom. Let soak for 5 full minutes. These LONG COATS need GREEN APPLE. are the sebaceous areas where most dirt and toxins enter the pet’s system. SHAMPOO: Dilute 1 part shampoo to 3 parts water in a clean container. Wet the coat & apply shampoo. Soak for 5 full minutes. Rinse. CONDITIONER: Dilute 1 part conditioner to 3 parts water in a clean container. Apply conditioner to coat. Soak for 5 full minutes. Rinse. Don’t see your breed? Please visit Please visit our info site http://isbusa.com/ instructions/akc-breeds-by-coat-type/ Frequently Asked Questions: SHORT COATS MEDIUM COATS LONG COATS Why are there different products for different American Foxhound Bernese Mountain Dog Afghan Hound breeds? All pet coats need oils, minerals and Staffordshire Terrier Brussels Griffon Bearded Collie collagen to thrive. However short coats need Basenji Cairn Terrier Bedlington Terrier more oils, medium coats need more minerals Basset Hound Cavalier King Charles Bichon Frise and long coats need more collagen. These Beagle Chesapeake Bay Retriever Bolonese products are created to provide the right Beauceron Chow Chow Chinese Crested balance of each for all coat types. Bloodhound Cocker Spaniel Coton De Tulear Why do I have to bathe per your instructions? Boston Terrier German Shepherd Havanese Since pets absorb dirt & toxins from the ground Boxer Golden Retriever Japanese Chin up into their sebaceous areas (tummy, feet, Great Dane Irish Wolfhound Lhasa Apso legs and other areas with less hair) it is Bull Terrier Keeshond Longhaired Dachshund important that the products are applied there Chihuahua Labrador Retriever Maltese first & allowed to soak for 5 min.
    [Show full text]
  • Dog Breeds of the World
    Dog Breeds of the World Get your own copy of this book Visit: www.plexidors.com Call: 800-283-8045 Written by: Maria Sadowski PlexiDor Performance Pet Doors 4523 30th St West #E502 Bradenton, FL 34207 http://www.plexidors.com Dog Breeds of the World is written by Maria Sadowski Copyright @2015 by PlexiDor Performance Pet Doors Published in the United States of America August 2015 All rights reserved. No portion of this book may be reproduced or transmitted in any form or by any electronic or mechanical means, including photocopying, recording, or by any information retrieval and storage system without permission from PlexiDor Performance Pet Doors. Stock images from canstockphoto.com, istockphoto.com, and dreamstime.com Dog Breeds of the World It isn’t possible to put an exact number on the Does breed matter? dog breeds of the world, because many varieties can be recognized by one breed registration The breed matters to a certain extent. Many group but not by another. The World Canine people believe that dog breeds mostly have an Organization is the largest internationally impact on the outside of the dog, but through the accepted registry of dog breeds, and they have ages breeds have been created based on wanted more than 340 breeds. behaviors such as hunting and herding. Dog breeds aren’t scientifical classifications; they’re It is important to pick a dog that fits the family’s groupings based on similar characteristics of lifestyle. If you want a dog with a special look but appearance and behavior. Some breeds have the breed characterics seem difficult to handle you existed for thousands of years, and others are fairly might want to look for a mixed breed dog.
    [Show full text]
  • The History of the BERGER PICARD
    The History of the BERGER PICARD By Betsy Richards hought to be the oldest upright ears, resembling in many ways a Beauce, or Beaceron). The mid-length of the French Sheep- Berger Picard of today. coat was ignored for some time, but final- dogs, the Berger Picard Of course it is not certain that the ly recognized as the Berger de Picardie was brought to northern Berger Picard originates strictly from the (or Picard). France and the Pas de Picardie region of France; it is possible, Although the Berger Picard made an Calais during the second even probable, that they were widespread appearance at the first French dog show TCeltic invasion of Gaul around 400 BC. as harsh-coated sheep and cattle dogs in 1863 and were judged in the same class Sheepdogs resembling Berger Picards were typical throughout northwestern as the Beaucerons and Briards, the breed's have been depicted for centuries in tapes- Europe. Some experts insist that this breed rustic appearance did not result in popu- tries, engravings and woodcuts. is related to the more well-known Briard larity as a show dog. In 1898 there was One renowned painting in the Bergerie and Beauceron, while others believe it proof that the Picard was a recognizable Nationale at Rambouillet (the National shares a common origin with Dutch and breed but it was tricolor, piebald with red Sheepfold of France) dating to the start Belgian Shepherds. brown markings. of the 19th century, shows the 1st Master Around the mid-19th century, dogs Picards would continue to be shown Shepherd, Clément Delorme, in the com- used for herding were initially classified and participate in herding trials but strug- pany of a medium-sized, strong-boned dog as one of two types: long hair (Berger de gled for recognition.
    [Show full text]
  • Ranked by Temperament
    Comparing Temperament and Breed temperament was determined using the American 114 DOG BREEDS Popularity in Dog Breeds in Temperament Test Society's (ATTS) cumulative test RANKED BY TEMPERAMENT the United States result data since 1977, and breed popularity was determined using the American Kennel Club's (AKC) 2018 ranking based on total breed registrations. Number Tested <201 201-400 401-600 601-800 801-1000 >1000 American Kennel Club 50% 60% 70% 80% 90% 1. Labrador 100% Popularity Passed 2. German Retriever Passed Shepherd 3. Mixed Breed 7. Beagle Dog 4. Golden Retriever More Popular 8. Poodle 11. Rottweiler 5. French Bulldog 6. Bulldog (Miniature)10. Poodle (Toy) 15. Dachshund (all varieties) 9. Poodle (Standard) 17. Siberian 16. Pembroke 13. Yorkshire 14. Boxer 18. Australian Terrier Husky Welsh Corgi Shepherd More Popular 12. German Shorthaired 21. Cavalier King Pointer Charles Spaniel 29. English 28. Brittany 20. Doberman Spaniel 22. Miniature Pinscher 19. Great Dane Springer Spaniel 24. Boston 27. Shetland Schnauzer Terrier Sheepdog NOTE: We excluded breeds that had fewer 25. Bernese 30. Pug Mountain Dog 33. English than 30 individual dogs tested. 23. Shih Tzu 38. Weimaraner 32. Cocker 35. Cane Corso Cocker Spaniel Spaniel 26. Pomeranian 31. Mastiff 36. Chihuahua 34. Vizsla 40. Basset Hound 37. Border Collie 41. Newfoundland 46. Bichon 39. Collie Frise 42. Rhodesian 44. Belgian 47. Akita Ridgeback Malinois 49. Bloodhound 48. Saint Bernard 45. Chesapeake 51. Bullmastiff Bay Retriever 43. West Highland White Terrier 50. Portuguese 54. Australian Water Dog Cattle Dog 56. Scottish 53. Papillon Terrier 52. Soft Coated 55. Dalmatian Wheaten Terrier 57.
    [Show full text]
  • Sixth Akc Rally® National Championship
    SIXTH AKC RALLY® NATIONAL CHAMPIONSHIP FRIDAY, MARCH 15, 2019 CENTRAL PARK HALL AT EXPO SQUARE 4145 EAST 21ST STREET – TULSA, OK 74114 TWENTY FIFTH AKC NATIONAL OBEDIENCE CHAMPIONSHIP SATURDAY & SUNDAY MARCH 16-17, 2019 AKC MISSION STATEMENT The American Kennel Club is dedicated to upholding the integrity of its Registry, promoting the sport of purebred dogs and breeding for type and function. Founded in 1884, the AKC® and its affiliated organizations advocate for the purebred dog as a family companion, advance canine health and well-being, work to protect the rights of all dog owners and promote responsible dog ownership. AKC OBJECTIVE Advance the study, breeding, exhibiting, running and maintenance of purebred dogs. AKC CORE VALUES We love purebred dogs. We are committed to advancing the sport of the purebred dog. We are dedicated to maintaining the integrity of our Registry. We protect the health and well-being of all dogs. We cherish dogs as companions. We are committed to the interests of dog owners. We uphold high standards for the administration and operation of the AKC. We recognize the critical importance of our clubs and volunteers. SIXTH AKC RALLY® NATIONAL CHAMPIONSHIP FRIDAY, MARCH 15, 2019 Sponsored in part by Eukanuba™ and J & J Dog Supplies TWENTY FIFTH AKC NATIONAL OBEDIENCE CHAMPIONSHIP SATURDAY & SUNDAY MARCH 16-17, 2019 Permission is granted by the American Kennel Club for the holding of this event under American Kennel Club rules and regulations. 1 Gina M. DiNardo, Secretary AKC BOARD OF DIRECTORS Ronald H. Menaker – Chairman Dr. Thomas M. Davies – Vice Chairman Class of 2019 Class of 2020 • Dr.
    [Show full text]
  • Fourth Annual BPCA National Specialty
    Fourth Annual BPCA National Specialty Licensed by the American Kennel Club Event Nos: 2016710903 and 2016710904 Sunday, October 9, 2016 11:00 AM Dog Training Club of Chester County 880 Springdale Drive, Suite 100 Whiteland Business Park, Exton, PA 19341 Judging will be Indoors-- Unbenched Leanne Chase, Show Secretary Certification ​ Permission is granted by the American Kennel Club for the holding of this event under American Kennel Club rules and regulations. James P. Crowley, Secretary 1 EMERGENCY, FIRE, POLICE, RESCUE: DIAL 911 Directions to The Dog Training Club of Chester County 880 Springdale Drive, Suite 100, Exton, PA 19341 From I-95: When nearing Philadelphia take exit 8 for US-202 N/Concord Pike toward W Chester. From I-76: Take exit 328A for US-202 S/US-422 W/ Swedesford Rd toward W Chester/Pottstown. The show site is in the Whiteland Business Park on Route 30 between Ship Road and the Route 202 / Route 30 Bypass Interchange. Turn into the business park at the traffic light onto Springdale Drive. It will be the first building on the left. The entrance faces Springdale Drive. Look for the black awning above the door. Parking is available in the lot across from the front entrance and along both sides of the building. SHOW VETERINARIAN Show Veterinarian (On Call & Emergency) Hope Veterinary Specialists 24 Hour Emergency Services Offered 40 Three Tun Road Malvern, PA 19355 610.296.2099 DIRECTIONS TO HOPE VETERINARY SPECIALISTS OFFICE: From the Dog Training Club of Chester County head northwest on Springdale Drive toward US-30 Bus E.
    [Show full text]
  • Stockdog Program Rules
    Stockdog Program Rules ASCA® is a registered trademark for the Australian Shepherd Club of America. Copyright© 2021 The Australian Shepherd Club of America. All rights reserved. 6091 E. State Hwy 21, Bryan, TX 77808 | (979) 778-1082 | www.asca.org 2 These rules were last updated: • August 27, 2021, to remove the Finals prize and rosette cost table from Section 24.5 Awards. This table can be found in the National Specialty Rules. • August 2021, to replace Stockdog Judge Directory. • May 2021, to prepare for June 2021 edition. Shaded areas indicate rule changes with effective date listed. The following contents are clickable links that will take you directly to that section. CONTENTS: Chapter 1 Purpose and Objectives .............................................................................................................................................. 6 Chapter 2 The Sanctioned Trial .................................................................................................................................................... 6 Section 2.1 The Sanctioned Trial ............................................................................................................................................. 6 Section 2.2 Herding Breeds Other Than Australian Shepherds ............................................................................................... 7 Section 2.3 Sanctioning of Trials.............................................................................................................................................
    [Show full text]
  • Texas Herding Association AKC Trial & Tests October 2,3,4 2020 Destiny
    Texas Herding Association AKC Trial & Tests October 2,3,4 2020 Destiny Farm, Bertram TX Friday 10/2/2020 - Trial 1 Course: D - Sheep Judge: Stacey Edwards Intermediate Place Armband Dog Breed Owner Handler Result Score Time 1 301 Ripple Australian Cattle Dog Sherry Clark Sherry Clark Q 79 20:53.00 Advanced Ties broken by best score on outrun, then time. Place Armband Dog Breed Owner Handler Result Score Time Tie breaker 1/H 103 Rey Border Collie Sherry Clark Sherry Clark Q 84 14:59.00 Carolynn Cobb 2/R 102 Trips Berger Picard Susan Frensley Pat Taylor Q 82 15:54.00 8.0 Michele McGuire 3 101 Cody Border Collie Michal Bagley Michal Bagley Q 82 16:29.00 7.0 4 104 Will Border Collie Mary Carter Mary Carter Q 81 12:20.00 Friday 10/2/2020 - Trial 2 Course: D - Sheep Judge: Kirsten Cole-MacMurray Intermediate Place Armband Dog Breed Owner Handler Result Score Time 1 601 Tuff Border Collie Diane Vercher Diane Vercher Q 81 12:36.00 2 602 Ripple Australian Cattle Dog Sherry Clark Sherry Clark Q 75 12:37.00 Advanced Place Armband Dog Breed Owner Handler Result Score Time 1/H 404 Cody Border Collie Michal Bagley Michal Bagley Q 86.5 13:43.00 Carolynn Cobb 2/R 403 Trips Berger Picard Susan Frensley Pat Taylor Q 83.5 13:24.00 Michele McGuire 3 401 Will Border Collie Mary Carter Mary Carter Q 79.5 13:30.00 402 Rey Border Collie Sherry Clark Sherry Clark NQ Texas Herding Association AKC Trial & Tests October 2,3,4 2020 Destiny Farm, Bertram TX Friday 10/2/2020 - Trial 3 Course: D - Sheep Judge: Stacey Edwards Intermediate Place Armband Dog Breed Owner
    [Show full text]
  • View the 2020 National Dog Show Program
    The National Dog Show Hosted by A Thanksgiving Tradition NOVEMBER 14 & 15, 2020 Broadcast at Noon Thanksgiving Day November 26 WELCOME Welcome to the National Dog Show hosted by the Kennel Club of Philadelphia. On behalf of the members of the Kennel Club of Philadelphia, I thank you for joining us today as we once again celebrate showing purebred dogs in the Philadelphia area. The show was founded in 1879 and became an annual event in 1933. The Kennel Club of Philadelphia proudly supports a number of canine related organizations and has donated over $500,000 to these groups in the past 5 years. The National Dog Show, airing annually on Thanksgiving Day at noon on NBC, has been thrilling dog lovers ever since it began in 2002, and we estimate that since then, one quarter of a billion people have watched! Enjoy the dog show, and let us know about your experience at www.facebook.com/ kennelclubofphiladogshows/. Happy Thanksgiving! WATCH THE Wayne Ferguson, President Kennel Club of Philadelphia NATIONAL DOG SHOW THANKSGIVING DAY HOSTED BY AT NOON, NOVEMBER 26, ON NBC. 1 personnel will not have access to the premises of viewers over Thanksgiving weekend, delivering WHAT’S DIFFERENT THIS YEAR? the Greater Philadelphia Expo Center in Oaks, Pa. its third-best score in total viewers since the first Still, dog shows have been organized around the broadcast in 2002. The show is part of a five-hour country throughout the summer and many of the block of family programming on NBC, offering EXPECT ANOTHER GRAND CELEBRATION best dogs in America live with their owners and the country’s 65 million pet-owning households a OF THE CANINE, MAN’S BEST FRIEND handlers in the northeast and mid-Atlantic states.
    [Show full text]
  • Mcnab Genetic Study
    McNab Genetic Study Mars Veterinary, 2017 Acknowledgements: Mars Veterinary would like to thank all the McNab owners and breeders who have donated samples to make this study possible. Contents Introduction & Purpose ................................................................................................................................ 2 Materials and Methods ................................................................................................................................. 2 Similarity to Known Breeds ........................................................................................................................... 4 Mixed Breed Algorithm ............................................................................................................................. 4 Clustering .................................................................................................................................................. 5 Principle Component Analysis (PCA) ......................................................................................................... 9 Disease Mutation Prevalence ..................................................................................................................... 15 Trait Prevalence .......................................................................................................................................... 16 Genetic Diversity Assessment ....................................................................................................................
    [Show full text]
  • Best in Grooming Best in Show
    Best in Grooming Best in Show crownroyaleltd.net About Us Crown Royale was founded in 1983 when AKC Breeder & Handler Allen Levine asked his friend Nick Scodari, a formulating chemist, to create a line of products that would be breed specific and help the coat to best represent the breed standard. It all began with the Biovite shampoos and Magic Touch grooming sprays which quickly became a hit with show dog professionals. The full line of Crown Royale grooming products followed in Best in Grooming formulas to meet the needs of different coat types. Best in Show Current owner, Cindy Silva, started work in the office in 1996 and soon found herself involved in all aspects of the company. In May 2006, Cindy took full ownership of Crown Royale Ltd., which continues to be a family run business, located in scenic Phillipsburg, NJ. Crown Royale Ltd. continues to bring new, innovative products to professional handlers, groomers and pet owners worldwide. All products are proudly made in the USA with the mission that there is no substitute for quality. Table of Contents About Us . 2 How to use Crown Royale . 3 Grooming Aids . .3 Biovite Shampoos . .4 Shampoos . .5 Conditioners . .6 Finishing, Grooming & Brushing Sprays . .7 Dog Breed & Coat Type . 8-9 Powders . .10 Triple Play Packs . .11 Sporting Dog . .12 Dilution Formulas: Please note when mixing concentrate and storing them for use other than short-term, we recommend mixing with distilled water to keep the formulas as true as possible due to variation in water make-up throughout the USA and international.
    [Show full text]