SAR1B Antibody Cat. No.: 55-163

SAR1B Antibody

Flow cytometric analysis of 293 cells (right histogram) Western blot analysis in MCF-7,MDA-MB453 cell line compared to a negative control cell (left histogram).FITC- lysates (35ug/lane). conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

Predicted species reactivity based on immunogen sequence: Bovine, Hamster, Mouse, Pig, HOMOLOGY: Rat

This SAR1B antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.

TESTED APPLICATIONS: Flow, IHC-P, WB

September 26, 2021 1 https://www.prosci-inc.com/sar1b-antibody-55-163.html For IHC-P starting dilution is: 1:50~100

APPLICATIONS: For WB starting dilution is: 1:1000

For FACS starting dilution is: 1:10~50

PREDICTED MOLECULAR 22 kDa WEIGHT:

Properties

This antibody is purified through a A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: SAR1B

ALTERNATE NAMES: GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB

ACCESSION NO.: Q9Y6B6

PROTEIN GI NO.: 14285769

GENE ID: 51128

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The protein encoded by this is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is BACKGROUND: part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.

September 26, 2021 2 https://www.prosci-inc.com/sar1b-antibody-55-163.html REFERENCES: 1) Cefalu, A.B., et al. Metab. Clin. Exp. 59(4):463-467(2010)

2) Silvain, M., et al. Clin. Genet. 74(6):546-552(2008)

3) Charcosset, M., et al. Mol. Genet. Metab. 93(1):74-84(2008)

4) Jardim, D.L., et al. J. Biochem. Mol. Biol. 38(3):328-333(2005)

ANTIBODIES FOR RESEARCH USE ONLY.

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September 26, 2021 3 https://www.prosci-inc.com/sar1b-antibody-55-163.html