THE JOURNAL

OF IMMUNOLOGY

Vol. XXIV MARCH, 1933 No. 3

PUBLISHED MONTHLY BY THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS

ADVISORY BOARD SIMON FLEXNER ROBERT MUIR THEOBALD SMITH New York. N. Y. Glasgow, Scotland Princeton, N. J. LUDVIG HEKTOEN G. H. F. ~UTTALL F. G. NovY Chicago, Ill. Cambridge, EngIand Ann Arbor. Mich. KARL LANDSTEINER WILLIAMH. PARK WILLIAM H. WELCH New York, N. Y. New York, N. Y. Baltimore, Md. A. E. WRIGHT London, England

CONTENTS H. M. POWELL, ~V. A. JAMIESON AND F. G. JONES. Merthiolate as a Preservative for Biological Products. III. Action of Merthiolate on Bacteriophage...... 185 JULIAN n. LEWIS. The Immunologic Specificity of Brain Tissue. 193 L. REINER. Comparison of the Combining, Antigenic, and Toxic Properties of Chemically Altered Diphtheria Toxoid and Toxin ...... 213 L. REINER. Adsorption of Diphtheria Toxoid by Cellulose De- rivatives and Iron Hydroxide Get ...... 221 ANNA DEAN DULANEY, WALTER T. WIKLE, R. L. STEWART, J. D. RAYFIELD, J. K. WALKER, JR., AND A. B. PREACHER. H and O Agglutination Following Typhoid Vaccination and in an Unselected Group of Individuals ...... 229 ANNA DEAN DULANEY AND WALTER T. WIKLE. H and O Agglu- tination in Typhoid Fever, Other Febrile Diseases, and in Vaccination ...... 235 JULES FREUND AND DEE E. FRANK. The Sedimentation Rate of Red Blood Cells of Tuberculous Rabbits Injected with Tuberculin ...... 247 L. DIENES. The Participation of Cutaneous Epithelium in Immu- nity Response ...... 253 MAalON B. SULZBERGER. Additional Note to the Article "Studies on Tobacco Hypersensitivity" ...... 265

THE WILLIAMS & WILKINS COMPANY BALTIMORE, U. S. A. Made in United States of Am,riea THE JOURNAL OF IMMUNOLOGY

EDITED BY ARTHUR F. CocA AND JOHN C. TORREY

BOARD OF EDITORS J. F. ANDERSON DENNIS EMBLETON W. H. MANWARING New Brunswick, N.J. London, England Leland Stanford Jr. Univ. JOHN AUER L.W. FAMULENER St. Louis J. MCINTOSH A. BREINL St. Luke's Hospital, N. Y. London, England Townsville, Queensland, J. G. FITZGERALD C. J. MARTIN Australia University of Toronto London, England J. BRONFENBRENNER St. Louis WILLIAM W. FORD M. J. ROSENAU Johns Hopkins University Harvard University C. H. BROWNING Glasgow, Scotland F. P. GAY J. HENDERSON SMITH WILLIAM BULLOCH Coll. of Phys. & Surg., N. Y. London, England London, England J. W. JOBLING R. P. STRONG RUFUS I. COLE Coll. of Phys. & Surg., N. Y. Rockefeller Institute Harvard University It. R. DEAN JOHN A. IHANS ZINSSER Cornell University London, England Harvard University

THE AMERICAN ASSOCIATION OF IMMUNOLOGISTS OFFICERS AND COUNCIL PAST PRESIDENTS Dr. A. B. Wadsworth, President New York State Department of Health, Dr. Gerald B. Webb Albany, New York Dr. James W. Jobling Dr. Arthur F. Coca, Sec'y-Treaa Dr. John A. Kolmer Pearl River Dr. William H. Park New York Dr. G. W. McCoy Dr. Rufus I. Cole Dr. A. B. Wadsworth Dr. Hans Zinsser Dr. A. R. Dochez Dr. Richard Weft Dr. Arthur F. Coca Dr. Frederick P. Gay Dr. Stanhope Bayne-Jones Dr. F. G. Novy Dr. Oswald T. Avery Dr. H. Gideon Wells Dr. Eugene L. Opie Dr. W.H. Manwaring Dr. Karl Landsteiner Dr. Ludvig Hektoen