Adults with DIABETES Are Among Those Who Need Pneumococcal

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Adults with DIABETES Are Among Those Who Need Pneumococcal

Patients with diabetes are at an increased risk for complications from pneumococcal disease. Diabetes may be a unique risk factor for increased incidence of sepsis associated with pneumococcal infection. One of the reasons people with diabetes are at greater risk for pneumococcal disease is that they may have abnormalities in immune function that affect their reaction to infection. Pneumococcal disease causes serious illnesses like pneumonia, meningitis, and sepsis. Pneumococcal disease is serious and deadly. In the US, pneumococcal pneumonia, meningitis, and sepsis kill tens of thousands each year. Pneumococcal disease survivors may suffer hearing loss, seizures, blindness, or paralysis. Pneumococcal vaccination is recommended for all adults with diabetes. Adults with DIABETES Are Among Those Who Need Pneumococcal Vaccination There are two types of pneumococcal vaccine recommended for US adults: a pneumococcal conjugate vaccine (PCV13) and a pneumococcal polysaccharide vaccine (PPSV23). Adults 65 and older, and adults age 19 to 64 years with any of the following need to receive both vaccines: immunocompromising conditions or treatments (e.g., HIV/AIDS, leukemia, lymphoma, Hodgkin disease, radiation therapy); a damaged or missing spleen; cochlear implants; or cerebrospinal fluid leaks. Other adults for whom pneumococcal vaccination is recommended only need PPSV23, but may need more than one dose and will need PCV13 when they, too, reach age 65. Please refer to the Adult Pneumococcal Vaccination Guide or visit cdc.gov/vaccines/vpd-vac/pneumo/ for details on timing of vaccine doses. For more information and resources to educate patients about pneumococcal disease, visit adultvaccination.org/professional-resources/pneumo This initiative is supported by unrestricted educational grants from Merck & Co., Inc. and Pfizer Inc. NFID policies restrict funders from controlling program content. October 2014 .

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AMERICAN ACADEMY OF PEDIATRICS Committee on Infectious Diseases Policy Statement: Recommendations for the Prevention of Pneumococcal Infections, Including the Use of Pneumococcal Conjugate Vaccine (Prevnar), Pneumococcal Polysaccharide Vaccine, and Antibiotic Prophylaxis ABSTRACT. Heptavalent pneumococcal conjugate vac- lular pertussis; HbOC, Haemophilus influenzae type b conjugate cine (PCV7) is recommended for universal use in chil- vaccine; HIV, human immunodeficiency virus; AOM, acute otitis dren 23 months and younger, to be given concurrently media. with other recommended childhood vaccines at 2, 4, 6, and 12 to 15 months of age. For children 7 to 23 months he purpose of this report is to provide recom- old who have not received previous doses of PCV7, ad- ministration of a reduced number of doses is recom- mendations for use of the heptavalent pneumo- mended. Two doses of PCV7 are recommended for chil- Tcoccal conjugate vaccine (PCV7), Prevnar (Led- dren 24 to 59 months old at high risk of invasive erle Laboratories, Pearl River, NY; Wyeth-Ayerst pneumococcal infection—including children with func- Pharmaceuticals, Marietta, PA), and 23-valent pneumo- tional, anatomic, or congenital asplenia; infection with coccal polysaccharide (23PS) vaccines. In addition, rec- human immunodeficiency virus; and other predisposing ommendations for the continuing use of antibiotic pro- conditions—who have not been immunized previously phylaxis in children with sickle cell disease (SCD) and with PCV7. Recommendations have been made for use of asplenia will be given, and the use of antibiotics and 23-valent pneumococcal polysaccharide (23PS) vaccine in vaccines in children who attend out-of-home care will high-risk children to expand serotype coverage.
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Individuals using assistive technology may not be able to fully access the information contained in this file. For assistance, please send an e-mail to: [email protected] and include 508 Accommodation and the title of the document in the subject line of your e-mail. HIGHLIGHTS OF PRESCRIBING INFORMATION ---------------------------------- ADVERSE REACTIONS---------------------------------- These highlights do not include all the information needed to use PNEUMOVAX 23 safely and effectiv ely. See full prescribing The most common adverse reactions, reported in >10% of subj ects information for PNEUMOVAX 23. vaccinated with PNEUMOVAX 23 for the first time in a clinical trial, were: injection-site pain/soreness/tenderness (60.0%), injection-site PNEUMOVAX® 23 (pneumococcal v accine polyv alent) swelling/induration (20.3%), headache (17.6%), injection-site erythema Sterile, Liquid Vaccine for Intramuscular or Subcutaneous (16.4%), asthenia and fatigue (13.2%), and myalgia (11.9%). (6.1) Injection To report SUSPECTED ADVERSE REACTIONS, contact Merck Initial U.S. Approv al: 1983 Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., at 1-877- ------------------------------- INDICATIONS AND USAGE------------------------------- 888-4231 or VAERS at 1-800-822-7967 or www.vaers.hhs.gov. PNEUMOVAX 23 is a vaccine indicated for active immunization for the -----------------------------------DRUG INTERACTIONS ---------------------------------- prevention of pneumococcal disease caused by the 23 serotypes In a randomized clinical study, a reduced immune response to contained in the vaccine (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F). (1.1) ZOSTAVAX® as measured by gpELISA was observed in individuals who received concurrent administration of PNEUMOVAX 23 and PNEUMOVAX 23 is approved for use in persons 50 years of age or older ZOSTAVAX compared with individuals who received these vaccines 4 and persons aged ≥2 years who are at increased risk for pneumococcal weeks apart.
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