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Missouri Medicine Missouri Medicine The Journal of the Missouri State Medical Association www.msma.org May/June 2013 NE MEDICINE O Collaborative Research on Human & Animal ONE MEDICINE Missouri University’s College of Veterinary Medicine & School of Medicine 155th Annual Convention Wrap Residency Crisis Retainer-Based Medicine A Physician's Duty to Warn Doctors in Unions? Opioid Drug Therapy Into the Future with Adult Day Care Missouri Medicine The Journal of the Missouri State Medical Association - Since 1904 Volume 110 | Number 3 | May/June 2013 www.msma.org/MissouriMedicine EDITOR’S DESK SCIENCE OF MEDICINE Dues, Dollars, Days, Diligence: Why They Matter to E=MC2 One Medicine: Collaborative Research on Human & Animal Disease for by John C. Hagan, III, MD ........................................................ 164 the Betterment of Both by Craig L. Franklin, DVM, PhD ................195 EDITORIAL Bitter Pill Promoting One Health: The University of by Arthur H. Gale, MD .............................................................. 166 Missouri Research Center for Human/Animal Interaction by Rebecca A. Johnson, PhD, RN................197 PERSPECTIVES The Doctor’s Office as a Union Shop A Brief History of Animal Modeling by David J. Lefell, MD .......................................... 170 by Aaron C. Ericsson, DVM, PhD, Marcus J. Crim, DVM Physicians Seek a More Personalized Approach & Craig L. Franklin, DVM, PhD ................... 201 in Retainer-Based Practice by Jim Braibish, APR ............................................ 172 New York Times Article Misleads on the Value of Mouse Models by Catherine E. Hagan, DVM, PhD ................................................ 206 Where Shall We Put All of Our Students? by Charles Van Way, III, MD ...................................................... 176 The Mighty Mouse: The Impact of Rodents on Advances in Biomedical Research DEAN’S REPORT by Elizabeth C. Bryda, PhD ......................... 207 From Simulators to Tablet Technology: KCUMB Leaps into the Future Advancing Swine Models by Marc B. Hahn, DO ......................................... 180 for Human Health and Diseases by Eric M. Walters, PhD MEDICAL-LEGAL & Randall S. Prather, PhD .............................................................. 212 A Physician’s Duty to Warn Others by Greg Minana, JD & Justin Stephens, JD ..................................... 184 Not Lost in Translation: How Study of Diseases in Our Pets Can Benefit Them and Us AS I SEE IT by Carolyn J. Henry, DVM The FDA: Incompetent? Stupid? & Jeffrey N. Bryan, DVM, PhD ...................................................... 216 Doesn’t Give a Damn? Or All the Above? John C. Hagan, III, MD ...................................... 188 Animal Models in Today’s Translational Medicine World by Abhishek Choudhary, MD FROM YOUR ASSOCIATION & Jamal A. Ibdah, MD, PhD ........................................................... 220 1 Picture = 1,000 Words .............................................................. 168 Correspondence ............................................................................ 190 The Laboratory Animal Veterinarian: More than just a Mouse Doctor 155TH ANNUAL CONVENTION REPORTS & HIGHLIGHTS by Cynthia G. Alvarado, DVM Meet MSMA’s President ................................................................. 242 & Lonny M. Dixon, DVM ........................... 223 Meet the MSMA Alliance President ................................................ 243 State of MSMA - Presidential Address ............................................ 244 Adult Day Care: An Important Long Term Care Alternative Presidential Inaugural Address ....................................................... 247 & Potential Cost Saver 50-Year Physician Pin ..................................................................... 248 by Richard E. Oliver, PhD & Meichele Foster .................. 227 Resolutions & Actions .................................................................... 249 Pain Management Mini-Series Part II Service Award ............................................................................... 251 Chronic Opioid Drug Therapy: Implications Legislative Award ........................................................................... 252 for Perioperative Anesthesia and Pain Management Sponsors & Exhibit Sponsors ......................................................... 253 by Robert B. Fisher DO, Quinn L. Johnson, MD Credentials & Appointments .......................................................... 253 & Joseph L. Reeves-Viets MD ......................................... 231 Council Minutes Summary ............................................................ 254 Reports of the Delegate Handbook ................................................ 259 Role of extracellular GAPDH in Streptococcus pyogenes Elections ........................................................................................ 267 Virulence Attendance .................................................................................... 268 by Kirsten Seidler & Norbert Seidler, PhD................ 236 MSMA member names in bold 113 Madison Street P.O. Box 1028 Jefferson City, MO 65102 800-869-6762 Fax: 573-636-8552 www.msma.org/MissouriMedicine Editor: John C. Hagan, III, MD [email protected] Managing Editor: Lizabeth R. S. Fleenor [email protected] Missouri Medicine |May/June 2013| 110:3 | 161 SCIENCE OF MEDICINE ONE MEDICINE Collaborative Research on Human & Animal Disease for the Betterment of Both by Craig L. Franklin, DVM, PhD MU is one of the few “Between animal and human medicine Mouse Regional Resource Center universities with a school there is no dividing line – nor should (MU-MMRRC http://www.mu-mmrrc. of medicine, college of there be. The object is different but the com), the Rat Resource and Research veterinary medicine, and experience obtained constitutes the basis of Center (RRRC http://www.rrrc.us), several strong departments all medicine.” and the National Swine Resource and ranging from biology Research Center (NSRRC http://www. to engineering, whose -Rudolf Virchow (1821-1902) nsrrc.missouri.edu). outstanding research is Moreover, MU maintains a devoted to the life sciences. The theme of this issue of Missouri number of other animal model- Medicine is animal modeling with an based resources including, but not emphasis on ongoing activities and limited to the National Cancer unique resources at the University of Institute’s Comparative Oncology Missouri (MU). Trials Consortium (COTC https:// MU is one of the few universities ccrod.cancer.gov/confluence/display/ with a school of medicine, college of CCRCOPWeb/Home), the Research veterinary medicine, and several strong Center for Human Animal Interaction departments ranging from biology (http://rechai.missouri.edu/), the to engineering, whose outstanding Christopher S. Bond Life Sciences research is devoted to the life sciences. Center (http://bondlsc.missouri.edu), As a result, MU is uniquely suited to the Laboratory for Infectious Disease advance ‘One Medicine,’ a concept Research (http://rbl.missouri.edu), and recognized by Virchow and Sir the Comparative Medicine Training William Osler, and now the lodestar of Program (http://cmp.missouri.edu). collaborative biomedical research. In a multi-department Through its Office of collaboration we present a collection Infrastructure Programs (within the of manuscripts that exemplify the Division of Program Coordination, broad range of comparative medicine Planning and Strategic Initiatives, initiatives at MU. Authors include Office of the Director), the National faculty and residents from MU’s Craig L. Franklin, DVM, PhD, dACLAM, Institutes of Health funds several School of Medicine, College of is Professor, Department of Veterinary animal resources (http://dpcpsi.nih. Veterinary Medicine, and School of Pathobiology, University of Missouri and gov/orip/cm/index.aspx). MU is home Nursing. For a history of animal coordinator of this One Medicine theme issue. Contact: [email protected] to three such resources: the Mutant models and a brief look into the Missouri Medicine | May/June 2013| 110:3 | 195 SCIENCE OF MEDICINE future, readers are referred to the manuscript by Ericsson nationwide studies of and therapeutic trials for cancer et al. Bryda builds on the discussion of rodent models in domestic animals. The definition of One Medicine is for disease and describes the MMRRC and RRRC, critical broadened by Johnson to studies of the human-animal centralized repositories for the preservation and distribution bond, which provides great benefit to both human and of rodent models that serve biomedical researchers across animal health. the globe. Walters and Prather change species and describe A common buzzword in today’s research is the growing use of swine in biomedical research with a translational medicine. To this end, Choudhary and Ibdah focus on how the NSRRC is using new genetic engineering discuss the translation of data from animal models to the tools to create swine models with distinct advantages over human condition, which drives progress of research along historical rodent models. Henry and Bryan introduce the the continuum from basic biomedical research findings concept of One Medicine which promotes the study of into clinical practice. Finally, Alvarado and Dixon describe naturally occurring diseases in companion animals for the the role of laboratory animal veterinarians as a bridge benefit of both animal and human patients. This is best between the humane use
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