Project Details

SEAC, Gujarat Page 1 of 29

Project details

 Synthetic Organic Chemicals 5(f)

 For Terms of Reference [ToR]

 New Project

1. Basic Information of the Project: i Name & Address of the Project site M/s. Androst Biotech (Complete details with plot no. /Survey no., Landmark etc. ) Plot No.: 23 to 26, G.I.D.C Estate, At. Sojitra Tal: Sojitra, Dist: Anand ii Name of the Applicant Mr. Pradip Darji

iii Address for correspondence M/s. Androst Biotech Plot No.: 23 to 26, G.I.D.C Estate,

At. Sojitra Tal: Sojitra, Dist: Anand iv Contact no. and e-mail ID of the Applicant Mo. no. :9924658753,9265026574 e-Mail: [email protected] v Aerial distance of nearest Habitat (KM) ~1 KM Name of village vi Longitude & Latitude of the Project Site: (4 22°31’46.27”N and 72°42’56.00”E corners of the site) 22°31’45.38”N and 72°42’59.06”E

22°31’43.83”N and 72°42’58.66”E

22°31’44.61”N and 72°42’55.56”E vii Category as per the Schedule to the EIA 5 (f) Synthetic Organic Chemicals Notification 2006 i.e. 1(d), 2(b), 5(f) etc. Sub-Category: B1 viii Applicability of General Conditions of No EIA Notification 2006: i.e. Ensure that (1) Protected areas notified under the Wildlife (Protection) Act, 1972; (2) CEPI areas (3) Eco-sensitive areas and (4) Inter-state boundaries and international boundaries; are not located within 5 km or 10 km (as the case may be) area from the boundary of the proposed site. Note: If located in Vapi-Sarigam region, kindly give exact aerial distance from the interstate boundary i.e. Boundary with Maharashtra state & U.T. of Daman, Diu and Dadra Nagar Haveli.

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viii In case of unit located outside the Notified No area: Complying the three conditions as per the amendment to EIA Notification, 2006 vide SO 1599 (E) dated 25/06/2014.

[i.e. water consumption less than 25 M3/day; Fuel consumption less than 25 TPD; and not covered in the category of MAH units as per the Management, Storage, Import of Hazardous Chemical Rules (MSIHC Rules), 1989] (Storage details of all the hazardous chemicals shall be submitted in tabular form for justification.)

2. Online application & PH reg. : a) Online application proposal no. : SIA/GJ/IND2/39661/2019 b) Date of online acceptance for ToR by SEAC: -- c) Date of presentation for ToR: --

3. Product profile: Quantity CAS Sr. No. Name of Product (Kg Per End User Number Month) 1 Hydroxyprogesterone caproate(HPC) 630-56-8 2 Nandrolone Decanoate 360-70-3 3 Nandrolone Phenylpropionate 62-90-8 1 500 4 Norethistrone 68-22-4 5 Norethistrone Acetate 51-98-9 6 Norethistrone Enanthate 3836-23-5 1 Estrone 53-16-7 Ethinyl Estradiol Final Products 2 57-63-6 Being Bulk 3 Dydrogesterone 152-62-5 Drugs(API) will be Utilized By 4 Estradiol Valerate 979-32-8 Pharmaceutical 2 5 Estradiol 50-28-2 150 Units For Formulation 6 Levonorgestrel 17489-40-6 7 Lynestrenol 52-76-6 8 Desogestrel 54024-22-5 9 Allylestrenol 432-60-0 1 Testosterone 58-22-0 3 2 Testosterone Decanoate 5721-91-5 200 3 Testosterone Propionate 57-85-2

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4 Testosterone Phenylpropionate 1255-49-8 5 Testosterone Enanthate 315-37-7 6 Testosterone Undecanoate 5949-44-0 1 Progesterone 57-83-0 4 2 Medroxyprogesterone Acetate 71-58-9 1000 3 Medroxy Progesterone 520-85-4 1 Mifepristone 84371-65-3 2 Dehydroepiandrosterone 53-43-0 3 Boldenone Undecylenate 13103-34-9 5 200 4 Tibolone 5630-53-5 5 Oxandrolone 53-39-4 6 Danazole 17230-88-5 1 Pregnelonone 145-13-1 2 Dydrogesterone 152-62-5 3 Fluticasone Propionate 80474-14-2 4 Fluticasone Furoate 397864-44-7 5 Ciclesonide 141845-82-1 6 Finasteride 98319-26-7 7 Drospirenone 67392-87-4 6 300 8 Spironolactone 52-01-7 9 Hyrocortisone 50-23-7 10 16-DPA (16-Dehydro Pregnenolone Acetate) 979-02-2 11 16-alpha hydroxy Prednisolone 13951-70-7 12 Ethisterone 434-03-7 13 Stanozolol 10418-03-8 14 Exmestene 107868-30-4 1 Rabeprazole 117976-89-3 2 Rizatriptan Benzoate 145202-66-0 3 Rivoroxaben 366789-02-8

4 Apixaben 503612-47-3 Final Products 5 Dabigatran 211915-06-9 Being Bulk Drugs(API) will 177036-94- 7 Ambrisentan and Darusentan and its 500 be Utilized By 6 1& intermediate Pharmaceutical 171714-84-4 Units For 7 Vilazodone 163521-12-8 Formulation 8 Aripiparazole 129722-12-9 9 Lemotrigine 84057-84-1 10 Irbesartan 138402-11-6

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11 Pregabalin 148553-50-8 ‎ 191732- 12 Lenalidomide 72-6 13 Pazopanib 444731-52-6 14 Sorafenib tosylate 284461-73-0 15 Sunitinib Maleate 341031-54-7 16 Abiraterone Acetate 154229-18-2 Ethyl chloro [(4-methoxyphenyl) hydrazono] 1 27143-07-3 acetate 3-Chloro-5,6-dihydro-1-(4-nitrophenyl)-2(1H)- 2 503615-03-0 pyridinone 3 3-Morpholin-4-yl-5,6-dihydro-1Hpyridin-2-one 545445-40-7 3-(4-Morpholinyl)-1-(4-nitrophenyl)-5,6- 4 503615-03-0 dihydro-2(1H)-pyridinone 5 (3β,8ξ,9ξ,14ξ)-17-Iodoandrosta-5,16-dien-3-ol 32138-69-5 6 3-(Diethylboryl)pyridine 89878-14-8 N,N-Dimethyl-3-(2-methylphenoxy)-3-phenyl 7 107688-86-8 propan-1-amine Oxalate 8 4-(methylamino)-3-nitrobenzoic acid 41263-74-5 9 Ethyl 3-(2-pyridylamino) propanoate 103041-38-9 3-[(3-amino-4-methylaminobenzoyl)-pyridin-2- 10 212322-56-0 yl-amino]-propionic acid ethyl ester 11 N-(4-Cyanophenyl)-glycine 42288-26-6 2-(2-Hydroxyphenyl)-4H-Benzo [e][1,3] 12 1218-69-5 oxazin-4-one Final Products Being Bulk (2-Butyl-5-nitrobenzofuran-3-yl)(4-hydroxy Drugs (API) will 8 13 141645-16-1 1500 phenyl) methanone be Utilized By (R)-5-Bromo-3-[(1-methyl-2- Pharmaceutical 14 143322-57-0 pyrrolidinyl)methyl]1H-indole Units. 5-Bromo-1H-indol-3-yl)[(2R)-1-methyl 15 143322-57-0 pyrrolidin-2-yl] methanone (1R)-2-{[2-(4-Nitrophenyl)ethyl]amino}-1- 16 521284-21-9 phenyl ethanol Hydrochloride (R)-2-[2-(4-Aminophenyl)-ethylamino]-1- 17 521284-22-0 phenyl ethanol Hydrochloride (1R)-2-{[2-(4-Nitrophenyl)ethyl]amino}-1- 18 223673-34-5 phenyl ethanol 5,6,7,7a-Tetrahydrothieno[3,2-c] pyridine- 19 115473-15-9 2(4H)-one Hydrochloride 2-Bromo-2-(2-fluorophenyl)-1- 20 204205-33-4 cyclopropylethanone 21 Cyclopropyl-2-fluorobenzyl ketone 150322-73-9 22 3-Isobutyl-pentanedioic acid dimethyl ester 145328-03-6 2-(1-Cyano-3-Methyl-Butyl)-,1,3-Diethyl ester 23 36082-57-2 Propanedioic acid 24 (+/-)-3-(Aminomethyl)-5-methylhexanoic acid 128013-69-4 25 5-Methylisoxazole-4-carboxylic acid 42831-50-5

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26 3-(4-Chlorobutyl)-1H-indole-5-carbonitrile 143612-79-7 Ethyl-5-amino-1-benzofuran-2-carboxylate 27 183288-42-8 Hydrochloride 28 5-(Piperazin-1-yl) benzofuran-2-carboxamide 183288-46-2 5-(1-Piperazinyl)-2-Benzofuran carboxylic acid 29 765935-67-9 ethyl ester Hydrochloride 4,5,6,7-Tetrahydrothieno [3,2-c] pyridine 30 28783-41-7 hydrochloride 1 Trimethyl ortho propionate (TMOP) 24823-81-2 9 2 Trimethyl ortho Valerate (TMOV) 13820-09-2 1500 3 Trimethyl ortho butyrate (TMOB) 43083-12-1

TOTAL 5850 -

The project falls under Category B of project activity 5(f) as per the schedule of EIA Notification 2006.

4. Product wise Raw materials consumption: Quantity Sr. Produc Product Name Raw Material Name in No. t Group Kg/Month 17-Alphahydroxy Progesterone 500.00 Toluene 4000.00 Para toluene sulfonic acid 20.00 HYDROXYPROGESTERONE N-Caproic anhydride 500.00 1 CAPROATE (HPC) Methanol 4100.00 Hydrochloric Acid 375.00 Dichloromethane 4000.00 DIPE 1500.00 Deconyl chloride 550.00 Pyridine 50.00 MDC 2500.00 2 Nandrolone Decanoate HCl 250.00 Nandrolone 400.00 Group Activated carbon 20.00 No: -1 Methanol 1000.00 Nandrolone 500.00 Phenylpropanoyl Chloride 650.00 Pyridine 50.00 NANDROLONE 3 Dichloromethane 2500.00 PHENYLPROPANOATE HCl 250.00 Methanol 1000.00 Activated Carbon 20.00 19-norandrostenedione 450.00 Acetyline gas 100.00 4 NORETHISTERONE Potassium Hydroxide 100.00 THF 2500.00 Methanol 1000.00

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Norethisterone 500.00 Acetyl Chloride 600.00 TEA 50.00 5 NORETHISTERONE ACETATE Dichloromethane 2500.00 HCL 250.00 Methanol 1000.00 Activated carbon 20.00 Norethisterone 500.00 Enanthyl Chloride 500.00 TEA 50.00 NORETHISTERONE 6 Dichloromethane 2500.00 ENANTHATE HCL 250.00 Methanol 1000.00 Activated carbon 20.00 ADD (Androstadienedione) 149.88 PTSA Catalyst 4.50 MDC 749.40 Triethylamine/Triethyl Orthoformate 83.93 Ethylene Glycol 74.94 THF 749.40 1 ESTRONE Biphenyl Methane 83.93 Sodium metal 53.96 Methanol 407.67 Hydrochloric Acid 194.84 Activated carbon 8.99 Acetone 1049.16 Estrone 150.00 Acetyline Gas 30.00 2 ETHINYL ESTADIOL Potassium Hydroxide 15.00 THF 450.00 Acetone 300.00 Progesterone 150.03 Group Ethylene Glycol 75.02 No: -2 MDC 750.15 PTSA 0.03 Activated carbon 9.00 3 DYDROGESTERONE DBH 66.25 Cyclohexene 2325.47 Na2CO3 30.01 Collidine 126.03 Ethyl acetate 1050.21 Estrone 150.00 Valeric anhydride 151.50 Pyridine 15.00 4 ESTRADIOL VALERATE Dichloromethane 750.00 HCl 75.00 Activated Carbon 6.00 Methanol 300.00 Estrone 150.06 5 ESTRADIOL NaBH4 15.01 NaOH 27.01

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Methanol 150.06 Acetic acid 52.61 Acetone 1200.48 Methoxy dienone 150.00 Tetra hydrofuran 600.00 Acetyline gas 33.00 Potassium tert-butoxide 22.80 6 LEVONORGESTREL Sulfuric acid 21.00 Methanol 750.00 Hydrochloric acid 17.10 Sodium carbonate 18.60 Nandrolone 150.00 Ethane-1,2-dithiol 300.00 Boron trifluoride etherate 75.00 Na metal 18.00 7 Lynestrenol Liq. Ammonia 60.00 Jones reagent 14.70 Potassium tert-butylate 14.85 Acetylene 82.50 Acetone 300.00 11α-hydroxy-18-methylnordione 149.70 p-Toluene sulfonic acid 14.97 1,2-ethanedithiol 59.88 Methanol 1871.21 Acetone 748.48 Dichloromethane 1122.73 Ethylene glycol 269.45 Triethyl orthoformate 209.58 Pyridine 13.47 Pyridinium dichromate 149.70 DMF 598.79 Magnesium 25.45 Iodine 67.36 Chloromethyl trimethylsilane 127.24 8 DESOGESTREL Dibromo ethane 29.94 THF 845.79 Toluene 748.48 Ammonium chloride 149.70 36% Aqueous HCI 14.97 Aqueous NaHC03 solution 22.45 KOtBu 149.70 Acetylene 149.70 tBuOH 22.45 Acetic acid 134.73 Sodium 14.97 Copper nitrate 2.99 Ammonia 299.39 Acetonitrile 37.42 Estrane-4-ene-17-one 150.00 9 ALLYLESTRENOL Allyl Chloride 180.00 Mg Turnings 15.00

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THF 450.00 MDC+Methanol 300.00 Activated Charcoal 6.00 4-Androstenedione (4-AD) 200.00 Triethyl orthoformate 400.00 Pyridine PTSA catalyst 2.80 HCl 83.00 1 Testosterone Methanol 1100.00 Sodium Hydroxide 56.00 Sodium Borohydride 14.60 Dichloromethane 600.00 Testosterone 200.00 Deconyl Chloride 240.00 Pyridine 20.00 2 Testosterone Decanoate Dichloromethane 1000.00 HCl 10.00 Methanol 400.00 Activated carbon 8.00 Testosterone 200.00 Propanoyl Chloride 240.00 Pyridine 20.00 3 Testosterone Propionate Dichloromethane 1000.00 Group Methanol 400.00 No: -3 Activated carbon 8.00 Testosterone 200.00 Phenylpropanoyl Chloride 240.00 Pyridine 20.00 4 Testosterone Phenylpropionate Dichloromethane 1000.00 Methanol 400.00 Activated carbon 8.00 Testosterone 200.00 Enanthyl Chloride 240.00 TEA 20.00 5 Testosterone Enanthate Dichloromethane 1000.00 Methanol 400.00 Activated carbon 8.00 Testosterone 200.00 Undecenoyl Chloride 240.00 Pyridine 20.00 6 Testosterone unDecanoate Dichloromethane 1000.00 Methanol 400.00 Activated carbon 8.00 4-Androstenedione 1000.26 Sodium Methoxide 550.14 Dimethyl Sulfoxide 1500.38 Acetyline Gas 180.05 Group 1 PROGESTERONE THF 1500.38 No: -4 1,4-Dioxane 7601.94 Copper Sulphate Alumina 200.05 Acetic Acid 2500.64 Toluene 7593.44

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Isopropyl Alcohol 200.05 Triethyl Amine 240.06 Formic Acid 106.03 Palladium Carbon 50.01 Methanol 5551.42 Sulfuric Acid 200.05 Activated Carbon 30.01 Medroxyprogesterone 1000.00 Medroxy Acetic acid 3000.00 2 PROGESTERONEAcetate Acetic anhydride 1100.00 Activated carbon 30.00 17-α Hydroxy progesterone 997.01 Benzene 4985.04 Ethylene glycol 1794.62 p-Toluene sulfonic acid 39.88 Pyridine 149.55 Chloroform 4985.04 Anhydrous sodium carbonate 1260.22 Anhydrous sodium sulfate 1260.22 3 Medroxy Progesterone Anhydrous sodium acetate solution of 74.78 peracetic acid Magnesium shavings 1026.92 Tetrahydrofuran 4985.04 Iodine 3589.23 H2SO4 1495.51 Glacial acetic acid 179.46 Activated carbon 29.91 Acetone 1994.02 Dienedione 200.00 Ethylene glycol 80.00 TosOH 8.00 MDC 800.00 1-Propynylmagnesium bromide 240.00 1 Mifepristone Hydrogen peroxide 40.00 THF 1600.00 HCl 20.00 4-Dimethylaminophenylmagnesium 160.00 bromide 4-Androstenedione (4-AD) 200.00 Group Tertiary butanol 1500.00 No: -5 Potassium tertiary butoxide 196.00 Acetic acid 114.00 DEHYDROEPIANDROSTERON Methylene chloride 1000.00 2 E Sodium ascorbate 70.00 Methyltetrahydrofuran 200.00 Pottasium phosphate 100.00 Sodium bicarbonate 10.00 Ethyl acetate 500.00 Boldenone 200.00 3 Boldenone Undecylenate Undecenoyl Chloride 240.00 Pyridine 20.00

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MDC 1000.00 HCl 100.00 Methanol 400.00 Activated carbon 8.00 Nandrolone 200.00 Isopropyl acetate 700.01 p-Toluene sulfonic acid 8.00 Triethylamine 10.00 Isopropanol 1800.04 Isopropenyl acetate 100.00 N-Bromosuccinimide 90.00 Lithium carbonate 40.00 Lithium bromide 20.00 Acetic acid 140.00 DMF 600.01 Tetrahydrofuran 1420.03 Methyl-magnesium chloride 50.00 37% Hydrochloric acid 20.00 Heptane 590.01 tert-Butyl methyl ether 1299.99 Toluene 400.01 Copper(II) bromide 300.01 Aqueous sulphuric acid 100.00 Aqueous sodium chloride 48.00 4 Tibolone Aqueous potassium hydroxide 48.00 Methanol 1599.99 Ethylene diamine tetra acetic acid 48.00 Liq. Ammonia 360.01 2-Propanol 220.00 Calcium metal 60.00 Ammonium chloride 200.00 tert-Butanol 60.00 Sodium hydrogen carbonate 24.00 2,6-di-tert-Butyl-4-methylphenol 130.00 Benzaldehyde 70.00 Aluminium tri-tert-butoxide 24.00 Aqueous solution of Lactic acid 44.00 Sodium chloride 8.00 Ethynyl magnesium chloride 520.01 Sodium chloride solution 20.00 Pyridine 1.20 Activated Carbon 20.00 Ascorbic acid 2.00 Ethanol 600.01 Hydrochloric acid 100.00 Mestanolone 200.00 IBX 300.00 Toluene 400.00 5 Oxandrolone Ethyl acetate 400.00 THF 2000.00 Acetone 400.00

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N-methylmorpholine N-oxide 240.00 1% aqueous solution of OsO4 100.00 Sodium metabisulphite 20.00 Dichloromethane 1200.00 Sodium metaperiodate 300.00 DMF 400.00 Sodium borohydride 40.00 1 N NaOH 4.00 3N Hydrochloric acid solution 4.00 DCM 800.00 17α-ethinyl-17β-hydroxy-3-oxo-4- 200.00 androstene Ethyl formate 240.00 Sodium ethoxide 20.00 Pyridine 20.00 6 DANAZOLE Hydroxylamine 120.00 Na-OCOCH3 120.00 Acetic acid 40.00 Methanol 800.00 Activated carbon 8.00 16-DPA 380.71 Ethanol 18807.11 Ranet Nickel 548.22 1 Pregnelonone Hydrogen 609.14 Methanol 1461.93 Potassium Carbonate 73.10 Progesterone 513.52 Mono ethylene Glycol 308.11 Paratoluene Sulfonic acid 0.10 Methylene Dichloride 2567.61 Methanol 5648.75 2 Dydrogesterone Cyclohexane 8216.36 N N-dibromohydantoin 239.10 Sodium Carbonate 102.70 2,4,6-s-collidine 513.52 Group Ethyl acetate 3594.66 No: -6 Flumetasone 320.35 Sodium Periodate 98.57 THF 246.43 Propionyl chloride 98.57 Triethyl amine 763.92 Diethyl amine 123.21 Acetone 6357.81 3&4 Fluticasone Furoate N,N-dimethyl thiocarbomyl chloride 98.57 Methyl Ethyl Ketone 1971.41 Sodium oidide 8.87 Morpholine 98.57 Ethyl acetate 123.21 HCL 591.42 Bromo fluoro Methane 98.57 Potassium Carbonate 98.57

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Furfuroyl chloride 123.21 Chloro form 1577.13 16-Alpha hydroxyprednisolone 255.00 Cyclohexane Aldehyde 90.00 Methane Sulphuric acid 60.00 Sodium hydroxide 390.00 MDC 5250.00 5 Ciclesonide N-Bromosuccinimide 120.00 Triphenyl phosphine 60.00 Methanol 1500.00 Sodium isobutoxide 90.00 Dimethyl Sulphoxide 150.00 16-DPA 498.01 Palladium Carbon 49.80 Methano; 2490.04 Hyflo 52.79 Hydrogen 9.96 Acetone 996.02 Sufuric acid 9.96 6 Finasteride Isopropyl alchohol 2490.04 Hydrogen Peroxide 99.60 Ammonia Solution 249.00 Palladium Carbon 29.88 p-Toluenesulfonic acid 9.96 Toluene 4482.07 tert-Butylamine 71.71 DDQ 219.12 PTSA 60.00 TEA 60.00 THF 798.00 D11 300.00 7 Drospirenone Charcoal/Hyflow 30.00 Methanol 720.00 MDC 840.00 IPA 159.00 Methyl Sulphonyl Chloride 184.80 Carrenone 330.00 8 Spironolactone Ethanol 2115.00 Potassium Thioacetate 231.00 Charcoal 30.00 Hyrocortictone acetate 323.53 Acetic acid 294.12 Methanol 2058.82 9 Hyrocortictone MDC 1470.59 Naoh 117.65 Methanol 1176.47 MDC 782.35 Prednisolone 360.00 16-ALPHA Triethyl ortho acetate 180.00 10 HYDROXYPREDNISOLONE Catalyst 1.50 Toluene 3300.00

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DMF 2700.00 L-Glutamic acid 12.00 Methanol 5400.00 Acetic anhydride 102.00 Pyridine 300.00 Potassium Acetate 12.00 Potassium Permanganate 276.00 Sodium hydrogen sulphate 60.00 Acetone 7500.00 KOH 6.00 Diosgenin 882.35 Acetic anhydride 388.24 Toluene 3529.41 Acetonitrile 7058.82 16-DPA (16-Dehydro 11 Tetraethyl ammonium iodine 7.06 Pregnenolone Acetate) Kmno4 321.18 Glacial Acetic acid 5647.06 Petroleum Ether 705.88 Methanol 3529.41 Dioxane 3960.00 IPA 504.00 KOH 1904.00 12 Ethisterone 4AD 320.00 HCL 2080.00 Methanol 792.00 Pet Ether 440.00 Oxymetholone 329.34 Diatomite 16.47 13 Stanozolol MDC 4793.41 Hydrazine 73.95 Trifluro Methane Sulphonic Acid 8.85 Toluene 707.96 BSTFA 1587.61 6-methylene-antrest-4ene-3,17-dione 383.48 Chloranil 356.93 14 Exmestene Ethyl Acetate 8849.56 Naoh +Nacl 3407.08 Ethyl Acetate 1474.93 IPE + n-Hexane 1032.45 Acetonitrile 1297.94 Charcoal 29.50 2,3 Lutidine 228.86 Hydrogen Peroxide(50%) 164.18 Nitric Acid 149.25 Sulphuric Acid 537.31 Group Acetic acid 228.86 1 Rabeprazole No: -7 3-Methoxy-1-Propanol 199.00 Sodium Hyrdoxide 328.36 Toluene 6716.42 DMSO 995.02 Acetic Anhydride 746.27

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HCl 99.50 Thionyl Chloride 263.68 MDC 6716.42 Sodium Sulphate 49.75 2-Mercaptobenzimidazole 263.68 Sodium hypochlorite(8%) 1626.87 Acetone 746.27 Sodium hydro sulphate 59.70 MMA in Methanol 49.75 Isopropyl Alcohol 1492.54 Carbon 49.75 4-Nitro benzyl bromide 383.04 1H-1,2,4-triazole 122.44 Potassium carbonate 122.44 Dimethyl formamide 1025.99 Ethyl Acetate 4103.97 IPA 1367.99 Toluene 2735.98 Methanol 7181.94 HCl 67.03 Cyclohexane 1367.99 CBDMA 231.87 Ethanol 2051.98 2 Rizatriptan Benzoate MTBE 1025.99 Dichloromethane 2051.98 Sodium sulphate 88.92 40 % Formaldehyde sol. 207.25 Formic Acid 127.22 Sodium Hydroxide 55.40 Benzoic aCID 159.37 Acetone 2051.98 Sodium nitrite 114.23 Activated Carbon+Hyflow 143.64 H2 Gas 16.42 Palladium on carbon 44.46 4-(4-aminophenyl)morpholin-3-one(APM) 338.69 2-[(2S)-2-oxiranylmethyl]-1H- 460.27 isoindole-1,3(2H)-diaone(Oxiran) Isopropyl alcohol 7134.17 N,N'-carbonydiimidazole(CDI) 416.85 Dimethylaminopyridine(DMAP) 34.74 Toluene 9109.86 Methylamine 521.06 3 Rivoroxaben Methanol 3547.55 Conc. HCl 790.27 5-Chlorothiophene 325.66 -2-carboxylic acid(CTA) Thionyl chloride 360.40 Dichloromethane 4971.78 Potassium Carbonate 447.24 Formic Acid 5227.96

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MNDP 283.72 CMPHEA 288.70 TEA 517.67 Ethyl Acetate 4892.98 Isopropyl alcohol 1144.85 HCl 149.33 Iron Powder 283.72 Ammonium Chloride 149.33 Methanol 7834.74 4 APIXABAN MDC 3379.79 Cyclohexane 248.88 Hyflow 288.70 Ammonia Gas 796.42 5-CVC 408.16 NaOH 184.17 DMAc 607.27 Activated carbon 29.87 DMSO 2628.17 3-[(1-Methyl-2-{[4-(5-oxo-4,5-dihydro- [1,2,4]oxadiazol-3-yl)-phenylamino]- methyl0-1H benzoimidazole-5-carbonyl)- 485.00 pyridin-2-yl-amino]-propionic acid ethyol ester P-toluene sulphonic acid 125.00 5 Dabigatran Acetic Acid 100.00 Ethanol 12500.00 Hexa Chloroformate 140.00 Acetone 6000.00 Pottasium Hydroxide 48.00 HCl 2.00 (s)-2-hydroxy-3-methoxy-3,3- 527.58 diphenylpropanoic acid Thionyl Chloride 263.79 Methanol 8633.09 Pottasium Chloride 479.62 Ambrisentan and Darusentan and 4,6-Dimethyl-2-(methylsulfonyl)pyrimidine 371.70 6 its intermediate Dimethylformamide 2637.89 Sodium Hydroxide 191.85 HCl(35%) 167.87 IPA 4796.16 Cyclohexane 5275.78 Methylene Dichloride 2877.70 Ethyl 5-(-4(5-cyano-1H-indol-3- yl)butyl)piperazib-1-yl)benzofuran-2- 538.32 7 Vilazodone carboxylate Ammonia Gas 18.25 Methanol 2281.02 7-Hydroxy-3,4-dihydroquinolin-2(1H)- 345.14 one(7-HDQ) 8 Aripiparazole 1-Bromo,4-Chloro Butane 2142.54 n-Propanol 1725.68 Sodium hydroxide 112.06

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Cyclohexane 3451.37 1-(2,3-Dichlorophenyl)piperazine 488.57 hydrochloride Ethanol 9412.82 Tetra butyl ammonium bromide 40.34 Triethyl amine 363.07 Activated Charcoal+hyflow 40.34 AGB 550.83 2,3 Dicholro benzyl cyanide 550.83 Conc. H2SO4 1652.48 NaOH Flakes 155.23 NaOH Sol.(40%) 385.58 9 Lemotrigine Methanol 2128.19 Acetic Acid 2233.35 Activated carbon 25.04 Liq. Ammonia 1622.43 Iso Propanol 1136.71 2-butyl-1,3-diazaspiro[4,4]non-1-ene-4- 412.12 one hydrochloride 5-[4'-(bromomethyl)biphenyl-2-yl]-1-trityl- 995.97 1H-tetrazole Methanolic Hydrochloride 122.51 Ethyl acetate 1778.94 Methanol 2371.92 10 Irbesartan Methylene Chloride 2016.13 Iso Propanol 2134.72 Toluene 1778.94 Acetone 1778.94 Sodium hyrdoxide lye 463.71 Sulphuric Acid 88.95 Activated Carbon 11.86 3-Carbamoyl methyl-5-methylhexaneoic 620.16 acid R-Methylbenzylamine 624.03 Toluene 9302.33 11 Pregabalin Sodium Hydroxide 620.16 Methanol 1550.39 Hydrochloric Acid 2480.62 Chloroform 775.19 Activated Carbon 23.26 Methyl 2-(bromomethyl)3-nitrobenzene 2169.15 3-aminopiperidine-2,6-dione hydrochloride 1630.29 DImethyl Formamide 91864.55 12 Lenalidomide Triethyl amine 1602.89 10 % Pd/C 130.15 Ethyl acetate 13014.89 Methanol 12690.66 2,3-dimethyl 2H-indazol-6-amine 891.30 4-Dichloropyrimidine 1108.70 13 Pazopanib Methanol 7407.61 Sodium Bicarbonate 1250.00 Ethyl Acetate 6760.87

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N-(2-chloropyrimidine-4-yl)-2,3-dimethyl- 777.17 2H-indazol-6-amine Cesium carbonate 1842.39 Iodomethane 440.22 DMF 2206.52 N-(2-chloropyrimidine-4-yl)-N2,3-trimethyl- 701.09 2H-indazol-6-amine 5-amino-2-methylbenzene sulfonamide 500.00 IPA 7744.57 HCl in IPA 10.87 (4-(4-Aminophenoxy)-N-methylpyridine-2- 196.58 carboxamide) 1-Chloro-4-Isocyanato-2-(trifluoromethyl) 183.76 benzene 14 Sorafenib tosylate Ethanol 4299.15 Activated Charcoal 34.19 Hyflow 68.38 Methylene Chloride 1085.47 p-Toluenesulfonic acid monohydrate 175.21 Ethyl-5-formyl-2,4-dimethyl-1H-pyrrole-3- 508.26 carboxylate Potassium Hydroxide 347.31 Methanol 54883.52 Hydrochloric Acid 537.91 Dichloro methane 5573.91 N,N-diethylethane-1,2-diamine 410.84 1-(3-diemthyl aminopropyl-3- 703.09 ethylcarbodimide HCl 1-hydroxybenzotriazole 495.55 Triethylamine 681.91 15 Sunitinib Maleate Dimethylformamide 2037.27 Toluene 660.74 n-Hexane 1016.52 Diethyl ether 338.84 Ethyl acetate 271.07 Sodium Chloride 135.54 Sodium bicarbonate 80.47 Sodium hydroxide 33.88 Pyrrolidine 4.24 Ethanol 5311.31 L-Malic Acid 118.59 Acetonitrile 15531.55 Dehydroeplandroosterone-3-acetate 624.39 (KSM) Trifluoromethane sulphonic anhydride 295.93 2,6-di-t-butyl-4-methylpyridine 253.66 Dichloromethane 21352.85 16 Abiraterone Acetate Hexane 30312.20 Magnesium Sulphate 68.29 Tetra hydro furan 1700.81 Diethyl(3-pyridyl)borane 87.80 Bis(triphenylphosphine)palladium(ii)chlorid 3.25

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e Sodium Carbonate 292.68 Diethyl ether 4744.72 Acetonitrile 1977.24 4-Methoxyaniline 1706.59 Sodium Nitrite 1167.66 Ethyl-2-chloroacetoacetate 2514.97 Sulfuryl chloride 2335.33 Hydrochloric Acid 2964.07 Ethyl chloro [(4-methoxyphenyl) 1 Sulfamic acid 628.74 hydrazono] acetate Sodium Acetate 2245.51 Ethyl Acetate 15269.46 Isopropyl Alcohol 6287.43 Sodium Chloride 538.92 Sodium Bicarbonate 7634.73 1-(4-nitrophenyl)pyridinone 2155.69 Methylene Dichloride 62874.25 Phosphorous Pentachloride 6017.96 3-Chloro-5,6-dihydro-1-(4- Isopropyl Alcohol 6287.43 2 nitrophenyl)-2(1H)-pyridinone Lithium Chloride 89.82 Lithium carbonate 359.28 Dimethylformamide 3592.81 Acetone 6287.43 Piperidin-2-one 1885.10 3-Morpholin-4-yl-5,6-dihydro- Morpholine 4937.16 3 1Hpyridin-2-one Phosphorous Oentachloride 3949.73 Methylene Dichloride 18850.99 Group 3-chloro-5,6-dihydro-1-(4-nitrophenyl)-2- No: -8 1500.00 3-(4-Morpholinyl)-1-(4- (1H)-pyridinone 4 nitrophenyl)-5,6-dihydro-2(1H)- Morpholine 1257.49 pyridinone Dimethylformamide 3592.81 Dehydroepiandrosterone 2686.57 Hydrazine Hydrate 11194.03 Methanol 44776.12 Methyl tert-Butyl ether 34029.85 Iodine 2686.57 (3β,8ξ,9ξ,14ξ)-17-Iodoandrosta- Hydrogen 111.94 5 5,16-dien-3-ol N-Methyl Morpholine 1119.40 Hydrochloric acid 671.64 Sodium Hydroxide 447.76 Sodium Thiosulfate 447.76 Ispopropyl Alcohol 11194.03 Cyclohexane 17910.45 3-Bromopyridine 2747.75 Ethyl Bromide 1936.94 Magnessium 855.86 Diethylmethoxyborane in Tetrahydrofuran 5405.41 6 3-(Diethylboryl)pyridine Ethyl Acetate 33333.33 Methanol 11261.26 Hydrochloric acid(35 %) 7657.66 Tetrahydrofuran 13513.51

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Sodium Carbonate 1666.67 Activated Carbon 135.14 Hyflo 360.36 Acetophenone 705.88 Dimethylamine Hydrochloride 529.41 Paraformaldehyde 235.29 Isopropy Alcohol 1764.71 Hydrochloric acid(35 %) 352.94 N,N-Dimethyl-3-(2- Sodium Hydroxide 235.29 7 methylphenoxy)-3-phenyl propan- 1-amine Oxalate Methanol 1882.35 Sodium Borohydride 176.47 Toluene 11176.47 Thionyl chloride 705.88 Acetone 5294.12 Sodium Borohydride 29.41 4-chloro-3-nitrobenzoic Acid 1620.00 4-(methylamino)-3-nitrobenzoic Aqueous Methylamine 3840.00 8 acid (Dabigatran Intermediate) Sulphuric acid 2370.00 Isopropanol 3000.00 2-aminopyridine 824.18 Ethyl 3-(2-pyridylamino) Ehtylacrylate 1310.44 9 propanoate (Dabigatran Intermediate) Acetic acid 206.04 Ehtylacetate 5769.23 4-Methylamino-3-Nitro-benzoic acid 1827.41 Thionyl Chloride 1827.41 Dithylformamide 152.28 Toluene 12182.74 Isopropyl Alcohol 3045.69 Triethylamine 2055.84 3-(Pyridin-2-ylamino Propionic acid ehtyl 3-[(3-amino-4- 1827.41 10 methylaminobenzoyl)-pyridin-2-yl- ester amino]-propionic acid ethyl ester Ethyl acetate 34263.96 Oxalic acid 913.71 Ammonia 913.71 Zinc 1979.70 Ammonium Chloride 2360.41 Carbon 76.14 Hyflo 532.99 4-Aminobenzonitrile 1706.59 11 N-(4-Cyanophenyl)-glycine Chloroacetic acid 4131.74 Sodium Bicarbonate 1347.31 Salicylic acid 1866.57 Salicylamide 1911.54 Thionyl Chloride 2248.88 2-(2-Hydroxyphenyl)-4H-Benzo 12 Toluene 13043.48 [e][1,3] oxazin-4-one Dimethylformamide 179.91 Methanol 9445.28 Sodium Bicarbonate 22.49 2-Butyl-5-Nitrobenzofuran 1576.58 (2-Butyl-5-nitrobenzofuran-3- 13 4-Methoxybenzoic acid 1576.58 yl)(4-hydroxy phenyl) methanone Thionyl Chloride 1261.26

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Methylene Dichloride 28378.38 Methanol 4954.95 Aluminium Chloride 3153.15 Toluene 8108.11 D-Proline 814.92 Benzyl chloroformate 1303.88 HCL 4156.10 Sodium Hydroxide 1635.28 Toluene 9708.44 Hexane 1064.83 Chlorobenzene 4357.12 DMF 97.79 (R)-5-Bromo-3-[(1-methyl-2- 14 Oxalylchloride 992.03 pyrrolidinyl)methyl]1H-indole. Mg Metal 412.89 Diethyl ether 2939.15 Ethyl bromide 1915.07 5-Bromo indole 1222.38 Sodium Bicarbonate 825.79 Vitride 4180.55 TFH 2716.41 Methanol 5541.47 2R -1- {(Benyloxy) carbonyl pyrrolidine - 2- 2286.37 carboxylic acid Methylene Dichloride 66512.70 Oxalyl Chloride 1212.47 5-Bromo-1H -indole 1836.03 Ethyl Magnesium Bromidein diethyl ether 3117.78 Hydrochloric acid(35 %) 5092.38 5-Bromo-1H-indol-3-yl)[(2R)-1- 15 Sodium Carbonate 2113.16 methyl pyrrolidin-2-yl] methanone Ethyl Acetate 45727.48 Methyl tert - Butyl ether 18360.28 Lithium Aluminium Hydride in 8071.59 Tetrahydrofuran Sodium Hydroxide 658.20 Toluene 42263.28 Hyflo 103.93 (R) -(-)Mandelic acid 1531.53 4-nitrophenethylamine Hydrochloride 2072.07 Hydroxybenzotriazole 1171.17 Triethylamine 1036.04 Dimethylformamide 8108.11 Ethyl Acetate 57207.21 (1R)-2-{[2-(4- N,N-Dicyclohexylcarbodimide 2252.25 16 Nitrophenyl)ethyl]amino}-1-phenyl Toluene 64864.86 ethanol Hydrochloride Sodium Sulfate 810.81 Hydrochloric acid 6441.44 Potassium Carbonate 4099.10 Tetrahydrofuran 20270.27 Sodium Borohydride 990.99 Boron Trifluoride Etherate 5990.99 Ammonia 7477.48

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Isopropyl Alcohol Hydrochloride 2612.61 Hydrochloric acid(35 %) 5585.59 1R -2- {(2-(4-Nitrophenyl)ethyl} amino -1- 2162.16 phynylethanol Hydrochloride (R)-2-[2-(4-Aminophenyl)- Hydrogen 45.05 17 ethylamino]-1-phenyl ethanol Palladium Carbon 2612.61 Hydrochloride Methanol 10810.81 Ethyl Acetate 11711.71 2R -2- Hydroxy -N-(4-Nitro Phenyl)ethyl) - 2 Phenyl ethanamide- {(Benyloxy) 2027.03 carbonyl pyrrolidine - 2-carboxylic acid Tetrahydrofuran 20270.27 (1R)-2-{[2-(4- Sodium Borohydride 990.99 18 Nitrophenyl)ethyl]amino}-1-phenyl Boron Trifluoride Etherate 5990.99 ethanol Hydrochloric acid(35 %) 5585.59 Ammonia 7477.48 Toluene 52702.70 Ethyl Acetate 22522.52 4,5,6,7,7a-Tetrahydrothieno[3,2-c] 2964.07 pyridine-2(4H) Hydrochloride Methylene Dichloride 14820.36 Triethylamine 3862.28 Methanol 27844.31 Triphenylmethyl chloride 5029.94 5,6,7,7a-Tetrahydrothieno[3,2-c] Sodium Sulphate 179.64 19 pyridine-2(4H)-one Hydrochloride Tributyl borate 10059.88 Hydrogen Peroxide 3772.46 Tetrahydrofuran 53892.22 Isopropyl Alcohol 15269.46 n-Butyllithium in Hexane 11856.29 Hydrogen Chloride 1077.84 Acetone 45808.38 2-(2-fluorophenyl) acetic acid 3693.69 Sodium Hydroxide 5135.14 Methylene Dichloride 27027.03 Hydrochloric acid(35 %) 7657.66 Cyclohexane 33333.33 Ethyl Cyclopropanecarboxylate 2252.25 2-Bromo-2-(2-fluorophenyl)-1- 20 Magnesium 1171.17 cyclopropylethanone Iodine 18.02 Tetrahydrofuran 40540.54 Isopropyl Bromide 5945.95 N-bromo Succinimide 1711.71 2,2-Azobisisobutyronitrile 90.09 Sodium Thiosulfate 2972.97 2-(2-fluorophenyl) acetic acid 3682.63 Sodium Hydroxide 5119.76 Methylene Dichloride 18862.28 Cyclopropyl-2-fluorobenzyl 21 Hydrochloric acid(35 %) 12395.21 ketone Cyclohexane 25149.70 Ethyl Cyclopropanecarboxylate 2245.51 Magnesium 1167.66

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Iodine 17.96 Tetrahydrofuran 40419.16 Isopropyl Bromide 5928.14 Isovalaradehyde 600.00 Diethyl Malonate 1125.00 3-Isobutyl-pentanedioic acid 22 n-Propylamine 60.00 dimethyl ester Acetic acid 75.00 Hexane 1800.00 Isovalaraldehyde 666.47 Diethyl Malonate 1257.49 n-Propylamine 73.65 2-(1-Cyano-3-Methyl-Butyl)-,1,3- 23 Acetic acid 628.74 Diethyl ester Propanedioic acid Hexane 1868.26 Sodium Cyanide 359.28 Ethanol 826.35 Isovalaraldehyde 1257.00 Diethyl Malonate 2370.00 n-Propylamine 138.00 Acetic acid 2685.00 Hexane 3540.00 (+/-)-3-(Aminomethyl)-5- 24 Sodium Cyanide 678.00 methylhexanoic acid Ethanol 1560.00 Potassium Hydroxide 1245.00 Raney Nickel 567.00 Hydrogen 60.00 Methanol 9690.00 Ethyl Acetoacetate 3772.46 Trithyl Orthoformate 4491.02 Acetic Anhydride 4491.02 Hydroxylamine Hydrochloride 1796.41 Methanol 12574.85 5-Methylisoxazole-4-carboxylic 25 Sodium Bicoarbonate 2065.87 acid Ethyl acetate 33233.53 Sulfuric Acid 3143.71 Hydrochloric acid(35 %) 1257.49 Sodium Hydroxide 359.28 Toluene 3592.81 1H-indole-5-carbonitrile 2702.70 4-chlorobutyl chloride 4009.01 Aluminium Chloride 5045.05 Methelene Dichloride 29729.73 Nitromethane 5405.41 Hydrochloric acid(35 %) 6756.76 3-(4-Chlorobutyl)-1H-indole-5- 26 Methanol 10810.81 carbonitrile Sodium Borohydride 1351.35 Tetrahydrofuran 10810.81 Ethyl acetate 32432.43 trifluroacetic acid 6486.49 Sodium Hydroxide 675.68 Isopropyl Alcohol 6756.76 27 Ethyl-5-amino-1-benzofuran-2- Ethyl-5-amino-1-benzofuran-2-carboxylate 1616.77

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carboxylate Hydrochloride Palladium Carbon 89.82 Ethyl Acetate Hydrochloride 2245.51 Hydrogen 89.82 Ethyl acetate 6287.43 Ethyl-5-amino-1-benzofuran-2-carboxylate 3333.33 Palladium Carbon 180.18 Ethyl Acetate Hydrochloride 4504.50 Hydrogen 180.18 Ethyl acetate 52252.25 Bis-2-chloroethyl amine Hydrochloride 2522.52 5-Methylisoxazole-4-carboxylic 28 O-xylene 31531.53 acid Acetone 14414.41 Methanol 39639.64 2-(2-Ethoxyethoxy)ethanol 3153.15 Sodium Carbonate 2927.93 Ammonia 270.27 tetrahydrofuran 6756.76 Ethyl-5-nitrobenzofuran-2-carboxylate 2804.15 Palladium Carbon 133.53 Ethyl Acetate Hydrochloride 3783.38 Hydrogen 133.53 Ethyl acetate 19139.47 5-(1-Piperazinyl)-2-Benzofuran Bis-2-chloroethyl amine Hydrochloride 2136.50 29 carboxylic acid ethyl ester Hydrochloride O-xylene 26706.23 Acetone 11572.70 Carbitol 2670.62 Potassium Carbonate 3115.73 Ehtyl Acetate Hydrochloride 17091.99 Methanol 13353.12 2-Thophene Ethylamne 1250.00 Formaldehyde 500.00 Sodium Sulphate 125.00 4,5,6,7-Tetrahydrothieno [3,2-c] DMF 5000.00 30 pyridine hydrochloride Hydrochloric acid 1300.00 Toluene 12500.00 Acetone 3000.00 PA 8000.00 Propionitrile 809.32 1 Trimethyl Ortho Propionate Methanol 939.44 Hydrochloric Acid 535.10 Valeronitrile 633.20 Group 2 Trimethyl Ortho Valerate Methanol 854.51 No: -9 Hydrochloric Acid 418.03 Butyrate 695.99 3 Trimethyl Ortho Butyrate Methanol 981.04 Hydrochloric Acid 368.87

5. Salient features of the project including Water, Air and Hazardous waste management:

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Sr. Particulars Details no. A A Total cost of Proposed Project 4.00 Crores (Rs. in Crores): B Total Plot area (sq. meter) 4211.76 .Sq. m. Green belt area (sq. meter) @ 1450 Sq. m. C Employment generation 10 D Water i Source of Water Supply GIDC Water Supply (GIDC Bore well, Surface water, Tanker supply etc...) Status of permission from the concern authority. We have already applied. ii Water consumption (KLD)

Category Quantity in KLD Remarks

(A) Domestic 1.00 (B) Gardening 4.0 (C) Industrial 12.6 KLD Fresh water Process 7.0 from GIDC Water Supply and remaining Washing 1.0 water will be reused Boiler 5.0 from Evaporator Condensate. Cooling 1.0 Utility(Make of HWG) 2.0 Industrial Total 16.0 Grand Total (A+B+C) 21.0 1) Total water requirement for the project:21 KLD 2) Quantity to be recycled: 8.4 KLD 3) Total fresh water requirement: 12.6 KLD iii Waste water generation (KLD) Category Quantity in KLD Remarks (A) Domestic Septic tank through 0.75 Soak Pit (B) Industrial

Process 8.00 Wastewater will be treated and then Washing 1.00 subjected to Boiler 0.50 Evaporator.

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Cooling 0.20 Utility(Make of HWG) 0.00 Total Industrial 9.70

Grand Total 10.45 iv Treatment facility within premises with capacity [In-house ETP (Primary, Secondary, Tertiary), MEE, Stripper, Spray Dryer, STP etc.  10 KL/Day primary ETP & in house evaporator. Treatment scheme including segregation at source.  -- Note: (In case of CETP discharge) : Management of waste water keeping in view direction under section 18 (1) (b) of the Water (Prevention and Control of Pollution) act, 1974 issued by CPCB regarding compliance of CETP.  N.A. Brief note on adequacy of ZLD (In case of Zero Liquid Discharge):  N.A. v Mode of Disposal & Final meeting point Domestic: Disposal to Septic Tank/Soak Pit Industrial: Wastewater will be treated and then subjected to Evaporator. vi In case of Common facility (CF) like CETP, Common Spray dryer, Common MEE etc. Name of CF  Not Applicable Membership of Common facility (CF) (For waste water treatment) Not Applicable vii Simplified water balance diagram with reuse / recycle of waste water

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viii Reuse/Recycle details (KLD) Total reuse…….KLD Source of waste Application Characteristics of Remarks water for reuse with area with waste water to be regarding quantity in KLD quantity in reused (COD, BOD, feasibility (From where it is KLD (Where it TDS etc.) to reuse i.e. coming) is used) 8.4 KLD from Process, --- -- Evaporator condensate washing, gardening E Air i Flue gas emission details No. of Boilers/TFH/Furnaces/DG sets etc. with capacities viz. TPH, Kcal/hr, MT/hr, KVA etc.

Fuel Stack Type of Sr. Stack attached Fuel consumption APC Height in emissions i.e. No. to Type rate in measures (Meter) Air Pollutants MT/Day

3792 Adequate 1 Boiler (2 TPH) 13 PNG SCM/Day Stack Height

Hot Water 610 SPM Adequate 2 Generator 11 PNG SCM/Day SO2 Stack Height (2.0 KCal/Hr) NOx Thermic Fluid 1220 Adequate 3 Heater 12 PNG SCM/Day Stack Height (4 Lac Kcal/hr.)

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D.G. set Adequate 4 9 Diesel 0.6 MT/Day (65 KVA) Stack Height

ii Process gas emission details i.e. Type of pollutant gases (SO2, HCl, NH3, Cl2, NOx etc.)

Specific Source of Stack/Vent Air Pollution Sr. Emission(Name of the Type of Emission Height Control Measures No. Product & Process) (meter) (APCM)

Two Stage Alkali 1 Reactor - 2 No. SO2 , NH3, 9 Scrubber

iii Fugitive emission details with its mitigation measures: As below:  The fugitive emissions during handling of material within factory premises will be controlled by taking appropriate engineering control measures. F Hazardous wastes (As per the Hazardous and Other Wastes (Management and Transboundary Movement) Rules 2016. i Type/Name of Category Sr. Specific Source Quantity Hazardous Schedule per Management of HW No. of generation (MT/Annum) waste HW Rules.

Collection, storage, From Plant transportation and sold 1 Used oil 5.1 0.05 machinery out to the registered Recyclers.

Collection, storage, ETP/Evaporator From ETP and transportation and 2 35.3 43.00 Residue Sludge Evaporator Plant disposal to authorized TSDF/CHWI facility.

Collection, storage, From transportation and 3 Process sludge manufacturing 26.1 215 disposal to authorized process CHWI facility. Collection, storage and Discarded From Raw reused for disposal of 4 containers / 33.1 9.00 material waste to sold to liners/barrels recyclers. Collection, storage, transportation and Spent carbon disposal to authorized 5 From Process 28.3 12.00 or filter medium CHWI facility or disposal by sending it to co-processing.

Collection, storage, transportation and Distillation 6 From distillation 36.1 3.60 disposal to authorized Residue CHWI facility or sold to recyclers.

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Collection, storage, transportation and From 7 Spent solvent 28.3 15 KL disposal through sale distillation/stripper to authorized recyclers. Collection, storage, Off specification Process Batch transportation and 8 28.5 1.5 Products Failure disposal by sending it to co-processing. ii Membership details of TSDF, CHWIF etc. We will be obtained membership certificate of (For HW management) TSDF. iii Details of Non-Hazardous waste & its disposal -- (MSW and others) G Solvent management, VOC emissions etc. i Types of solvents, Details of Solvent recovery, % recovery, reuse of recovered Solvents etc. (Details in Table Format)  Details of solvent recovery will be covered in EIA report. ii VOC emission sources and its mitigation measures  Details of VOC emission will be covered in EIA report. H  Details regarding storage of Hazardous chemicals Storage details Name of major Hazardous Remarks chemicals Drum/Barrel storage Methanol, Toluene, MDC,IPA, Acetone, Ethyl acetate etc.

 Applicability of PESO : Not Required

6. Details of Environmental Consultant: Sr. No. Particulars Details i Name of the Consultant Ramans Enviro Services Pvt. Ltd. ii Contact no. and e-mail ID of the Mo. no. :9924444188 Consultant e-Mail: [email protected] iii Accreditation for the categories Accredited for 5(f) and December - 2019 and Validity iv Any other details --

Page 28 of 29 ToR-New [Updated MARCH 2019] SEAC, Gujarat Page 29 of 29

Name & designation of the Applicant: Pradip Darji

Stamp & Signature of Applicant:

Date: 20.07.2019

General Instructions:

 Format shall be in WORD Format (Font type- Arial, Font size- 11)  Do not change Format. Fill up your details / information in prescribed tables.  Provide authenticated (with stamp & Signature) hard copy during presentation.  Kindly send e-mail to : [email protected]  Above data shall be as per application Form-1 & PFR.  Incorporate relevant details in respective column in the Format. Do not attach Annexure except copy of Certificates etc.

Page 29 of 29 ToR-New [Updated MARCH 2019] Check list for Industrial Projects

For submission of application for Terms of Reference

[TOR cases]

 Provide authenticated (with stamp & Signature) hard copy of this check-list during submission of

hard copy of ToR application.

Tick Sr. Information/Details Page no. of whichever is no. Application applicable 1 All columns of Form 1 (As prescribed in EIA Yes -- Notification 2006) properly filled by Project proponent (PP). [All pages signed by PP] 2 Documents related to Land ownership No Annexure - K & L Included in Form-1 3 For 5 (f) category Yes --  Project site is located within GIDC  If No, Compliance of following conditions  Water consumption < 25 KLD No --  Fuel Consumption <25 MTPD No --  Non-MAH Unit No -- 3 Contact details provided Yes As part of SEAC Format and Form -I Mobile no. and e-Mail ID included in Form-1 4 Format prescribed by SEAC [Salient features of Uploaded the project] included with application. Yes 5 General Condition applicability. Project site is not -- located within the 5 Km or 10 km of the following No as the case may be: (1) Protected areas notified under the Wildlife (Protection) Act, 1972; (2) CEPI areas (3) Eco-sensitive areas and (4) Inter-state boundaries and international boundaries; are not located within 5 km or 10 km (as the case may be) area from the boundary of the proposed site. 6 In case of Expansion, Compliance status of No Our unit proposed existing unit is included in Format (as per Format) project 7 Violation of EIA Notification 2006 -- No Has any construction activity or project activity started? If yes, details submitted in this regard No --

8 Product profile with CAS no. / CI no. Yes Annexure -A

9 Raw Material details and manufacturing process Annexure -B &C of all products with CAS no. / CI no. Yes

Spent Acids (H2SO4, HCl etc.) generation. No -- 10 If Yes, it is considered as Haz. Waste & Submitted No -- its management. 11 Details regarding Source of water, Water balance Yes Annexure -D included in Form-1  Permission to obtain fresh water  Waste water management,  Membership certificate of common facility,  Permission letter for discharge of waste water etc. 12 Flue gas emission details Included in Form-1 Yes Annexure -F Process gas emission? Yes Annexure -F If yes, Management details Yes

13 Hazardous waste generation & Yes Annexure -E its management

Spent solvent generation? Yes Annexure -F 14 If, yes Management of spent solvent included in application? Yes 15 Fugitive emissions? -- Yes If yes, details of its management submitted. Yes 16 VOC details included in Application? -- Yes

If yes, details of its management submitted. Yes

Above details are true to the best of my knowledge and I am abided to respect the decision of the SEIAA/SEAC if above information stands wrong in the future and also agree to initiated the legal proceedings against my project.

Name & designation of the Applicant: Mr.Pradip Darji Stamp &Signature of Applicant:

Date: 20.07.2019