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10-11-1990 Washington University Record, October 11, 1990

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This Article is brought to you for free and open access by the Washington University Publications at Digital Commons@Becker. It has been accepted for inclusion in Washington University Record by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. gNJCMiington WASHINGTON ■ UNIVERSITY- IN ■ ST' LOUIS *W8e»j —s l&CORD Vol. 15 No.7/Oct. 11, 1990 Key role University is named one of four centers to map human genome The School of Medicine has been tists will lead this national effort." designated one of the Public Health Among the biggest scientific Service's first four centers of investiga- undertakings in history, the Human tion for the federally funded human Genome Project will decipher the genome initiative — a project with the genetic messages locked away in each goal of deciphering the complete of the body's cells. The complete set genetic message of human beings at of messages, or genome, is inscribed the molecular level. The designation in the 100,000 or so genes on 23 pairs brings with it a five-year grant with a of chromosomes. One of the project's first-year award of $2.3 million from five-year goals is the development of the National Institutes of Health to maps showing the location of the establish a new Human Genome genes on each of the chromosomes. A Center at Washington University. later goal is the exact sequencing of "This is wonderful recognition of the molecular "base pairs" that the strengths this institution has constitute the chromosomes and amassed in the area of genetics provide a code for protein production. research," says Chancellor William H. The Washington University Danforth. "The diligence and creativity project has three parts, each based on of our fine faculty have once again the power of Yeast Artificial Chromo- secured for us a key role in an some (YAC) technology. YACs were important national research initiative." developed in the Washington Univer- The results of the highly competi- sity laboratory of Maynard V. Olson, tive national selection process will be Ph.D., professor of genetics, and have formally announced in Washington, increased the capabilities of the D.C., through the National Center for molecular geneticist's lab by a full Human Genome Research, a compo- order of magnitude over conventional nent of NIH established to oversee its techniques. Through YAC technology, part of the Human Genome Project. large portions of the human genome "It's a huge task, but it's more of are introduced into yeast chromo- an investment than an expense," says somes that are adopted and then David Schlessinger, Ph.D., professor of cloned by the plant. Because of their Student-athlete Chris Warlick at work in a genetics laboratory at the School of Medicine. genetics, who will direct the new size, the clones can hold even large genome center at Washington Univer- genes intact and can be overlapped to Has to pass on football game sity. Schlessinger adds that when the reconstruct maps of large parts of the genome is adequately mapped, human genome. Student-athlete will present "scientists can efficiently work out all The St. Louis center aims to of human biology at the molecular continue the development of technol- level. This is the best route to under- ogy for genome analysis while gene discovery at conference standing most, if not all, of the 4,000 reaching its three goals. The first is to When you refer to Chris Warlick as a the country in an attempt to further inherited diseases." locate a number of genes of special student-athlete, you'd better put map the human gene structure. "This is a great opportunity; medical or research interest in YACs. "student" in boldface — maybe an Warlick's main focus was an area understanding the human genome will "For example," Schlessinger says, "we exclamation mark or two. of a chromosome near the disease yield enormous benefits to mankind," know that genes in a particular region On Oct. 20, Warlick, the Bears' familial hypertrophic cardiomyo- says William A. Peck, M.D., vice of about 4 million base pairs are top-notch wide receiver, won't be on pathy — a genetic heart ailment that chancellor for medical affairs and responsible for the rejection of the field when his fellow teammates often affects young people. It's a dean of the School of Medicine. transplanted tissues. Using YAC take on Colorado College. Instead, he disease with no outward symptoms, a "Washington University School of technology we have been locating and will be in Cincinnati, Ohio, attending disease that can strike quickly and Medicine is proud to be among the cloning these genes," in work led by the national convention of the Ameri- fatally. In the process, he discovered institutions whose outstanding scien- Continued on p. 4 can Society of Human Geneticists. two markers that will make the whole More than 100 presentations will be region much more useful toward made at this annual conference, which further research, says Donis-Keller. Czech composer Martinu is focus of attracts more than 5,000 top medical Warlick's discoveries will soon specialists. Only one of those presen- become a permanent fixture on the international conference and festival tations will be made by an under- updated human genetic map, and will In honor of the 100th anniversary of "Martinu and 20th-century Music," graduate student — Chris Warlick. bear his initials — CW1 and CW2. Czech composer Bohuslav Martinu's which is joindy sponsored by the Last spring, Warlick, a senior "They actually had names like birth, the University will host an International Research and Exchanges biology major, uncovered two markers G8I1 and G8B4," says Warlick, who is international conference and festival, Board (IREX) and Washington on the map of the human gene from Williamsville, N.Y. "But my titled "Martinu and 20th-century University's Department of Music, was structure. These markers will help doctor said those names were too Music." The festival will be held Oct. organized by Michael Beckerman, scientists isolate the cause of a heart messy. She said, 'Let's just call them 21-28 and the scholarly conference Ph.D., associate professor of music, ailment that often afflicts young CW1 and CW2. I thought that was will run Oct. 24-27. and will feature 30 scholars and people. kind of nice." Washington University's event musicians from Czechoslovakia, "Chris Warlick? Oh, you mean our Warlick, who just began playing culminates a year-long series of Russia, England, Germany, Switzer- next Nobel laureate?!" quips Helen college football last fall, is very celebrations that included Martinu land and Cuba. Donis-Keller, Ph.D., perhaps only half- disappointed that he will miss the festivals in Prague, London, Barcelona, Because there has been a ten- jokingly. "I'd say it's absolutely Colorado College contest. Paris and Konstanz, Switzerland. dency to view Martinu as a Czech unheard of for an undergraduate to "It's a concern because I've only Martinu (1890-1959) was a phenomenon, the Washington Univer- give a presentation at the national been playing two years — just 19 contemporary of Bartok and sity symposium will explore the meeting. I don't know of a single games," he says. "It's l/19th of my Stravinsky, and, like them, spent part composer's relationship within the instance when it's happened. Most career that I'm missing. But this is an of his life as an exile in the United larger 20th-century artistic climate and, postdoctorates consider it quite an option that I really can't pass up." States, as well as in France, Switzer- more specifically, with other compos- honor to give a talk at the meeting," His father played the game land and Italy. His many travels, ers of his time, including Schoenberg, adds Donis-Keller, a professor of professionally. A tight end, Ernie however, did not stop him from Sibelius and Prokofiev, as well as genetics at the School of Medicine Warlick was a member of the Buffalo composing. Martinu was one of the Bartok and Stravinsky. who oversaw Warlick's research. Bills from 1962-65. According to Chris, most prolific composers of the 20th "Martinu has a very curious The tide of his work is "Isolation his father never goaded him into century, writing more than 400 relationship with the 20th century," of a Yeast Artificial Chromosome playing. compositions, including 12 ballets, 13 says Beckerman. "Although an exile Clone From D14S26 Near a Gene for "Quite the opposite in fact," he operas, six symphonies, 25 concertos for much of his life, his music harkens Familial Hypertrophic Cardiomyopathy recalls. "My dad is anything but the and more than 75 chamber works. His back very strongly to his Czech roots. and Identification of Two New stereotypical football father. When I musical style is considered eclectic — There are striking juxtapositions of Restriction Fragment Length Polymor- was eight and told him that I wanted incorporating elements of jazz, beautiful harmonious strains and phism Probes at this Locus." to play football, he said 'Are you sure impressionism and Czech folk music powerful dissonances in Martinu's Warlick began working in a you want calcium deposits in your — yet distinctive and powerful. music that aren't always appreciated genetics lab at the Washington ankles? Are you sure about this?' He In homage to Martinu's own for their complexity and impact. University Medical Center in the wasn't really discouraging me, but he eclecticism, the festival will include a "It's as if the batde between the summer of 1989- This past spring, his was letting me know what I was marionette play, an evening of Czech dissonance of human life and the lab work was part of an ongoing getting myself into." folk music, a solo piano recital and a search for peace and repose is con- project involving several labs around Continued on p. 2 percussion ensemble. Continued on p. 3 Fourth show added due to sellout Hemingway's only play to be staged "The Fifth Column," Ernest Heming- more Elizabeth Kodner as Dorothy way's only play, will be staged before Bridges; senior Foster Solomon as sold-out audiences at 8 p.m. Friday Max; and junior Declan Fitzpatrick as and Saturday, Oct. 19 and 20, and at 2 Preston. David Kuhns, Ph.D., visiting p.m. Sunday, Oct. 21, in the Drama assistant professor in the Performing Studio, Room 208, Mallinckrodt Arts Department, is directing the play. Center. Because of the sellout, a Other production members are fourth show has been added. It will Daniel File, set designer, Ann Ciecko, be held at 7 p.m. Oct. 21. lighting designer, Nora Yockey, Tickets are $7 for the general costume designer, Joe Clapper, public and $5 for senior citizens, technical director, and Rise Sanders, students and Washington University sound designer. faculty and staff. To purchase tickets, call 889-6543. Authors explore the The play is part of the Performing Arts Department conference titled 'man and the myth' "Ernest Hemingway: The Man and the In conjunction with the Heming- Myth" being held Oct. 18-20 in Edison way conference, two lectures that are Theatre. free and open to the public will be The conference also will include given. panel discussions and paper presenta- Hemingway scholar Michael tions from major Hemingway scholars. Reynolds will speak on "Hemingway Admission to the conference is free to for Our Time" at 11 a.m. on Oct. 17 in University students, faculty and staff. Edison Theatre. For the general public, the cost of the Reynolds, who is a professor of three-day event is $35; single day English at North Carolina State Univer- admission is $10. sity, has written six books and numer- The Washington University ous articles on Hemingway, including production of "The Fifth Column" is the 1989 book Hemingway: The Paris the world premiere of the A.E. Years. Reynolds' 1986 biography, The Hotchner adaptation of Hemingway's Young Hemingway, received a Pulitzer script and had Hemingway's approval. Prize nomination. He is now working Hotchner, a 1940 graduate of the on a third volume about Hemingway, University, will attend the premiere. who died in 1961, and his literature. Paul Winter, founder of the Paul Winter Consort, will bring his nature music to Edison Theatre Saturday, Hemingway wrote "The Fifth An editorial board member of the Oct. 20, when the group presents two shows — a children's program at 2 p.m. and an evening Column," which is set in the Spanish performance at 8 p.m. Hemingway Review, Reynolds is Civil War, in 1937 while living in the serving a two-year term on the Hotel Florida in Madrid. executive committee of the The author later said of the Hemingway Society. He also was When Paul Winter plays, experience, "The play was written in program director for the Fourth the fall and early winter of 1937 while International Hemingway Conference, wolves, whales & eagles call we were expecting an offensive ... which took place this year. while we waited I wrote the play. The lecture is co-sponsored by the Blending jazz, classical and folk down the Colorado River three times. Each day we were shelled by the guns Assembly Series, Department of Eng- traditions with wolf, whale and eagle Each trip required a crew of 27 and ... and while I was writing the play the lish and Department of Performing Arts. calls, the Paul Winter Consort will more than five tons of supplies and Hotel Florida, where we lived and The second lecture will be given perform at 8 p.m. Saturday, Oct. 20, in equipment. The album, "Canyon," was worked, was struck by more than by MacDonald Harris, author of the Edison Theatre. The event is part of released in 1985 and spawned a one- thirty high explosive shells. So if it's 1990 book Hemingway's Suitcase, a the "OVATIONS!" series. hour Public Broadcasting Service not a good play perhaps that is the fictional account of a fact-based inci- The consort also will present a special on the making of the album. matter with it, if it is a good play, dent involving writer Hemingway. special one-hour children's program at In 1986 the consort performed in perhaps those thirty-some shells Harris' lecture, titled "The Making of a 2 p.m. Oct. 20 in Edison Theatre. This Japan and Russia, where Winter met helped write it." Novel: Fact, Fake, and Fiction," will be event is part of the "ovations! for the Dimitri Pokrovsky Singers in Hotchner, author of the 1966 given at 10 a.m. Saturday, Oct. 20, in young people" series. Moscow. The two groups collaborated Papa Hemingway, used Hemingway's the Drama Studio, Room 208, in Formed in 1967, the consort on "Earthbeat," the first album of original script of "The Fifth Column" Mallinckrodt Center. The event is co- released three albums in its first four original music created jointly by as the basis for his adaptation. sponsored by the Bookmark Society years. The consort's album "Icarus" Americans and Russians. The cast for "The Fifth Column" and the Performing Arts Department. went along on the Apollo 15 trip to In addition to touring extensively, features graduate student Brad Harris' book, Hemingway's Suit- the moon in 1971, and two lunar the consort members have been Schwartz as Philip Rawlings; sopho- case, focuses on an event that occur- craters were named after songs on the artists-in-residence in New York's red early in Hemingway's career. In album, "Icarus" and "Ghost Beads." Cathedral of St. John the Divine — the 1922, a suitcase containing 20 short The ensemble has been a leader world's largest Gothic cathedral — stories and part of a novel was stolen in the field of nature music since 1977, since 1980. from Hemingway's wife, Hadley, and when "Common Ground," its first Tickets are $18 for the general RECORD was never recovered. In Hemingway's album to mix actual nature sounds public; $14 for senior citizens and Suitcase, the main character, second- with jazz compositions, was released. Washington University faculty and rate novelist Nils Frederick Glas, claims In one of its most ambitious staff; and $9 for students. Tickets for Editor: Susan Killenberg, 889-5254, to have discovered the lost manuscripts projects, the consort used the Grand Campus Box 1070; P72245SS at WUVMC the children's performance are $7. For Assistant editor: Carolyn Sanford, 889-5293, and attempts to publish them. Canyon as a recording studio, rafting box office hours, call 889-6543. Campus Box 1070; P72245CS at WUVMC Harris is the author of 15 vol- Editor, Medical Record: Joni Westerhouse, umes of fiction and a co-founder of 362-8257, Medical School Campus Box 8065; the Writing Program at the University C72245JW at WUVMD of California, Irvine. He will examine continued from p. 1 Contributing writers: Debby Aronson, Debra Student-athlete Bernardo, Joyce Bono, Kleila Carlson, Gerry the elements needed to create a novel Everding, Tony Fitzpatrick, Fran Hooker and in Hemingway's mode. Accepted into both Dartmouth While he could return to the Steve Kohler and Johns Hopkins, he instead chose gridiron next fall as a graduate Photographers: Joe Angeles, Tom Heine, Washington University after receiving student, medical school — perhaps at David Kilper and Herb Weitman Library exhibit the full-tuition John B. Ervin Scholar- Record (USPS 600-430; ISSN 1043-0520), Washington University — is his top Volume 15, Number 7/Oct. 11, 1990. Published The Washington University ship, awarded to talented college- priority. weekly during the school year, except school Libraries, in conjunction with the bound black high school students. "I think it's time to move on," he holidays, monthly during June, July and August, Performing Arts Department, also is Warlick was the team's third- says. "I've loved the blend of academ- by the Office of Public Affairs, Washington University, Box 1070, One Brookings Drive, sponsoring a Hemingway exhibit titled leading receiver in 1989, nabbing ics and athletics here at Washington St. Louis Mo. 63130. Second-class postage paid "Hemingway and Popular Culture." eight passes for 109 yards. His season University. I don't have much to at St. Louis, Mo. The exhibit, on display from Oct. 15 highlight came against Colorado compare it to, but I get the feeling that Address changes and corrections: through Jan. 15, 1991, in Special College — the opponent he will be this is pretty close to optimal. Coach Postmaster and non-employees: Send Collections, Level 5, Olin Library, missing this year — when he caught Kindbom has a great attitude. He address changes to: Record, Washington documents the public's perception of his first career touchdown. University, Box 1070, One Brookings Drive, realizes that studies come first, and he St. Louis, Mo. 63130. Hemingway — the man and the writer This fall, Warlick is a key reason tells us that from the beginning and Hilltop Campus employees: Send to: Person- — as depicted in the stage and screen the Bears are off to their best start in reiterates it throughout the year. That nel Office, Washington University, Box 1184, adaptations of his work. recent years with a 4-2 record. He attitude is the way it should be. One Brookings Drive, St. Louis, Mo. 63130. Medical Campus employees: Send to: Payroll For more information or to ranks second on the team with 13 Athletics are important — but they Office, Washington University, Box 8017, receptions and 255 yards through six should never come at the expense of 660 S. Euclid, St. Louis, Mo. 63110. register for the Hemingway confer- games. Warlick is also second in team your academics." DavidMoessner ence, call 889-5858. scoring, with three touchdowns and a two point conversion to his credit. NOTABLES

Mary-Jean Cowell, Ph.D., associate conferences are presented by graduate professor of dance, was invited to students. Victor T. Le Vine, Ph.D., Alumni, Brookings awards teach a series of master classes at professor of political science, and Southern Illinois University at Eugene B. Shultz, Ph.D., professor of Edwardsville. engineering and policy, both interna- to be given at Founders Day tional affairs faculty members, also Washington University will honor six ment Co. Ltd., has interests in such Clark D. Cunningham, J.D., associ- participated in the conference. Le Vine alumni and three members of the areas as high technology, construction, ate professor of law, presented a was a respondent to the presentation University community at this year's financial services and venture capital. paper tided, "A New Way of Practicing of the keynote speaker, Tebego Founders Day Banquet on Saturday, He is also a professor of neurosurgery Law: The Lawyer as Translator," to the Mafole, chief representative of the Oct. 13, at the Adam's Mark Hotel, at Taipei Medical College in Taiwan. faculty of the Law & Society program African National Congress to the Fourth and Chestnut Streets. The • Bertram W. Tremaynejr. has at Macalester College in St. Paul, Minn. United Nations. He also was a mem- banquet, commemorating the been a practicing attorney since his He presented the same paper at the ber of the Plenary Panel on the University's founding in 1853, will graduation from the School of Law in University of Wisconsin Law School in Development of Human Rights in the begin with cocktails at 6:30 p.m. 1938. He also received a bachelor's Madison under the sponsorship of the Middle East. Shultz served as program Pulitzer Prize-winning columnist degree from the University in 1935. Institute for Legal Studies. He also chair for the conference and delivered William Safire will be the guest He is a member of the Law Alumni presented the paper at the annual a paper tided "Third World Learning speaker at the event, which is spon- Association Executive Committee, meeting of the Law & Society Associa- Experiences for American Students: sored by the Washington University chair of the Law Annual Fund, chair of tion in Berkeley, Calif. The Trans-Disciplinary Promise" as Alumni Association. the Annual Fund for the Alumni Board part of a panel on "Educating Ameri- To make reservations or for of Governors, and a Scholar in Law Derek Hirst, Ph.D., professor of can Students About the Third World." ticket information, call 889-5122. sponsor. He and his wife, Clara, a history, delivered a paper titled The Distinguished Alumni Award 1935 graduate of the University, are "Understanding Britain: the Experi- Richard J. Walter, Ph.D., professor is given in recognition of outstanding Fellows of the Eliot Society. ence of Unification Under the Repub- and acting chair of the Department of professional achievement, contribu- • Olh/W. Wilson Jr., professor lic, 1649-60" at a conference on History, presented a paper on "Nation- tions in areas of public service, of music and past assistant chancellor Multiple Kingdoms held at the Univer- alism and Internationalism in the exceptional service to the University, for international affairs and associate sity of Illinois. Development of Socialist and Labor or any combination of the three. The dean of the graduate division at the Movements in Latin America" at a con- following alumni will be honored. University of California at Berkeley, James M. McKelvey, Ph.D., dean of ference on comparative labor history • Harold Guller, who was has composed works for the nation's the School of Engineering and Applied held at Alkmaar, the Netherlands. drafted into World War II before major symphony orchestras, as well as Science, received the 1990 Technology completing his degree in the School of chamber ensembles and electronic Award of the St. Louis Regional Com- Gerhild Scholz Williams, Ph.D., Engineering and Applied Science, media. His compositions and record- merce and Growth Association (RCGA) chair of the German department, founded Essex Industries Inc., a ings have received international at a dinner held at the Breckenridge delivered invited lectures on "Litera- military contractor and life-saving critical acclaim. He received a Frontenac Hotel. He was honored for ture and Magic" in early modern component manufacturer. Today, he is bachelor's degree in music from the his dedication to the advancement of French and German literature at the chairman emeritus and chief executive University in 1959. technology, for his leadership in Universities of St. Gallen and officer, guiding the company's con- The three recipients of the Robert bringing the Washington University Lausanne, Switzerland, and at the tinuing diversification with his brother, S. Brookings Award have been chosen engineering school to national promi- Universities of Augsburg and Sidney, and two sons. He and his by the Board of Trustees as individu- nence, and, according to the RCGA Saarbrucken, West Germany. wife, Mildred, were early sponsors of als who, by their commitment and science and engineering committee, the Engineers' Scholarship Program, generosity, exemplify the alliance for "his untiring generosity and Have you done something and he is a Life Member of the between Washington University and commitment to serve our community." noteworthy? William Greenleaf Eliot Society. He its community. The Brookings Award and Sidney established the Guller recipients follow. Marsha B. Shepley, Jean L. Shultz Have you: Presented a paper? Won an award? Scholars Program for students in the Been named to a committee or elected an • George W. Couch HI, chair- and L. Virginia Vehaskari, who are officer of a professional organization? joint B.S./M.B.A. program. man of the board and president of the pursuing master's degrees in the The Washington University Record will help • Sidney H. Guller, a 1947 Couch Distributing Co. in Watsonville, International Affairs Program, and spread the good news. Contributions regarding business school graduate, joined his Calif., established an endowed chair, Yukihiro Hoshino, who received a faculty and staff scholarly or professional activities are gladly accepted and encouraged. brother, Harold, at Essex Industries the Gregory B. Couch Professorship in master's degree from the program in Send a brief note with your full name, highest- Inc. after graduation. Now chairman Psychiatry, at the School of Medicine 1989, presented papers at the 16th earned degree, current title and department and chief financial officer/treasurer of in 1987 for research on schizophrenia. Annual Third World Conference held along with a description of your noteworthy activity to Notables, Campus Box 1070, or by the company, he is a leading volun- With his mother, Geraldine G. Couch, in St. Louis. Typically, only about one- electronic mail to p72245SS at WUVMC. Please teer for the John M. Olin School of and brother, Geoffrey A. Couch, he fifth of contributed papers at the include a phone number. Business. Guller is a member of the also contributed additional funds for school's Capital Gifts Committee and office and research facilities that will has served on its Eliot Society Mem- focus on new approaches for the bership Committee and Special Gifts treatment and cure of schizophrenic Martinu continued from p. 1 Committee. He and his wife, Bobette, disorders. He is a Life Patron of the tinually being re-enacted in Martinu's The ensemble includes a children's are Life Members of the Eliot Society, Eliot Society. works," Beckerman observes. "As an choir. and were founding sponsors of the • Clifford W. Murphy, who exile, he roamed a world teeming Other events in the festival will Scholars in Business Program. attended engineering classes at with conflict, yet his pastoral vision of include: • Herbert F. Hitzemanjr. Washington University following his home became ever stronger. • The St. Louis debut of Boris devoted 24 years of his career to World War II service, created the "Martinu was born in a church Krajny, considered one of the finest Washington University. As senior vice Clifford W. Murphy Professorship in tower, high above the countryside," Czech pianists, in a recital featuring chancellor for university relations, the Civil Engineering in 1988. Founder of adds Beckerman. "This summer, when Martinu in the context of Debussy and position from which he retired in Drilling Service Co., which pioneered I visited the tower with several music Ravel. June, he directed one of the most hard-rock drilling and tool and graduate students, we were all struck • The St. Louis-based Bob Kramer successful advancement programs at equipment efficiency, Murphy co- by the connection between the still Marionettes performing Act 2 of any American university. A 1953 founded the Earl Salveter Memorial landscape and the lyrical calm that Martinu's fairy tale ballet "Spalicek." A graduate of the School of Fine Arts, Scholarship Committee at the School pervades Martinu's work. Indeed, cobbler who has a series of adven- Hitzeman also strengthened alumni of Engineering and, with his wife, many scholars and musicians consider tures, including a game of chess with relations through a more active Armarie, established the school's this 'view from the tower' the source "Death," is the centerpiece of this folk Alumni Board of Governors and the Clifford W. and Armarie B. Murphy of the inner tranquility so characteris- story. creation of a new international alumni Scholarship. The Murphys are Life tic of his compositions." • A concert by Martin Kaplan and chapter network. The Herbert F. Patrons of the Eliot Society. Beckerman, who hosted a similar Josef Fiala (Pepik), two folk musicians Hitzeman Jr. Residence Hall was • Melba Seay has been dedicated and highly successful conference here Beckerman met on the picturesque named in his honor last June. He and to the progress of Washington Univer- two years ago on Czech composer Charles Bridge in Prague — the city's his wife, Jane, also an alum, are sity for many years. In 1975, she and Leos Janacek, says, "Martinu's reputa- landmark overlooking the Moldau Annual Fellows of the Eliot Society. her husband, the late A. Forest Seay tion is not quite fixed yet. He's starting River where street musicians congre- • Shi Hui Huang is a highly Jr., established the Seay Professorship to get a lot of attention and it's an gate. regarded neurosurgeon and a promi- in Clinical Neuropharmacology at the exciting time to come to an honest "It was fascinating — after years nent international businessman. After School of Medicine to pursue new evaluation of his work." of hiding in pubs during the old neurosurgical training at the School of developments in treating neurological Jaroslav Pelikan, a renowned regime, all these wonderful musicians Medicine, Huang established a neuro- disorders. After her husband's death, historian of Christianity and an active began appearing on Charles Bridge," surgery center at Yodogawa Christian she established the Seay promoter of U.S.-Czechoslovak says Beckerman of the experience of Hospital in Osaka, Japan. He returned Neuropharmocology Research Fellow- scholarly relations, will give the meeting Kaplan and Fiala. "These two to Barnes Hospital's neurosurgery ships and the A. Forest Seay Jr. keynote address during the were the absolute best." department in 1975. In 1979, Huang Scholarship Fund for business school conference's opening ceremony, In their concert, "Martin and took over his family business in students. A Life Patron of the Eliot which is being held at 4 p.m. Thurs- Pepik," as they are known profession- Taiwan, the San Yang Industry Co. Society, she also created the only day, Oct. 24, in Graham Chapel. Also ally, will demonstrate many of the Ltd., a major manufacturer of Honda known business librarianship, the Asa at the opening ceremony, the haunting and unusual ballads of south automobiles and motorcycles. His F. Seay Librarianship in Business. Vysocina Choir, a local group, will Bohemia that, in an indirect way, holding company, Ching Fong Invest- sing Martinu's moving cantata titled relate to Martinu's music. "The Opening of the Wells," which Admission to the conference is celebrates a Moravian children's free and open to the public. For ticket custom of cleaning the woodland information on festival events, or for pools every spring, and serves as a more information about the confer- metaphor for postwar rejuvenation. ence, call 889-5574. CALENDAR Oct. 11-20

4 p.m. Dept of Chemistry Seminar, "Intaglio Prints From the Rug Series," 7 p.m. Women's Soccer, WU vs. University of "Intramolecular 4 + 3 cycloadditions: Progress featuring the work of printmaker and visiting Missouri-Rolla. Francis Field. LECTURES and Problems," Michael Harmata, prof., U. of WU artist-in-residence Lloyd Menard. Through Missouri, Columbia. Room 311 McMillen. For Oct. 28. Bixby Gallery, Bixby Hall. 10 a.m.-4 Friday, Oct. 19 Thursday, Oct. 11 more info., call 889-6530. p.m. weekdays; 1-5 p.m. weekends. 3 p.m. Volleyball National Invitational. Illinois Benedictine, UC-San Diego, UW- 1-2:30 p.m. Dept of History Lecture, Robert 4:30 p.m. Dept of Mathematics Colloquium, "Caliban's New Master: The Emergence of Whitewater, Nebraska Wesleyan, College of St. Ivanov, prof., Institute of General History, "Adapted Bases in Signal Processing and Medicine in Early Modern Europe (1450- Benedict, University of La Verne, Wheaton, 111., U.S.S.R. Academy of Sciences, will give an open Analysis," Mladen Victor Wickerhauser, Yale 1700)." Through Jan. 3, 1991. Rare Books and WU. Field House. (Also, Saturday, Oct. 20.) presentation during the course Black America to and University of Georgia. Room 199 Cupples I. Division, Seventh Floor, School of Medicine the Civil War. Room 100 Busch Hall. He also Library, 660 S. Euclid Ave. 3:30 p.m. Women's Tennis. WU vs. University will participate in an informal discussion on the Friday, Oct. 19 of Evansville. Tao Tennis Center. writing of history under Glasnost from 4-5:30 Noon. Cell Biology and Physiology Seminar 4 p.m. Men and Women's Swimming and p.m. Cohen Lounge, Busch 113. Series, "The Role of Acidic Compartments in Diving Time Trials. Millstone Pool. Sorting of Proteins in the Regulated Secretory 4 p.m. Central Institute for the Deaf FIIMS Pathway," David Parkinson, WU Dept. of Cell Saturday, Oct. 20 Seminar, "What Can Spike Discharges in a Biology and Physiology. Cell Biology and 11 a.m. Women's Soccer. WU vs. University of Frog's Auditory Nerve Tell Us About Mammalian Physiology Library, 4th Fl., McDonnell Medical Friday, Oct. 12 Chicago. Francis Field. Hearing?" Don A. Ronken, Sensory Biophysics 7 and 9:30 p.m. Filmboard Feature Series, "A Sciences Bldg. For more info., call 362-6950. 1 p.m. Men's Soccer. WU vs. University of Laboratory, WU Institute for Biomedical Boy Named Charlie Brown." (Also Sat., Oct. 13, 4 p.m. School of Medicine's 18th Annual Chicago. Francis Field. Computing. 2nd Fl. Aud. Clinics and Research at 2, 7 and 9:30 p.m. and Sun., Oct. 14, at 2 and Carl Vernon Moore Memorial Lecture, "G Bldg., 909 S. Taylor Ave. 7 p.m.) $3. Room 100 Brown Hall. Proteins and the Regulation of Adenylyl 4 p.m. Dept. of Chemistry Seminar, Cyclase," Alfred G. Gilman, prof, and chair, Midnight Filmboard Midnight Series, "Time "Mechanistic Studies on the Formation of Dept. of Pharmacology, U. of Texas Southwest- Bandits." (Also Sat., Oct. 13, same time, and Organic Ring Systems Using Transition Metal MISCELLANY ern Medical Center at Dallas. Moore Aud., 1st Sun., Oct. 14, at 9:30 p.m.) $3. Room 100 Brown Templates," R. Hughes, Dartmouth. 311 Fl., North Bldg., 4580 Scott Ave. Hall. On Fit and Sat., both the 9:30 p.m. and McMillen. midnight films can be seen for a double feature Saturday, Oct. 13 8 p.m. School of Fine Arts Lecture by Bruce 4:30 p.m. Dept of Mathematics Colloquium, price of $4; both Sun. films can be seen for $4. 9 a.m. Committee on Comparative Litera- Davidson, free-lance photographer and "Regularity Theory for Maps of Bounded ture "Symposium on Homer: Scholarly filmmaker. Steinberg Hall Aud. For more info., Distortion," Gaven Martin, prof., U. of Michigan. Monday, Oct. 15 Work In Progress." (Also Oct. 14, beginning at call 889-6500. Room 199 Cupples I. 7 and 9:30 p.m. Filmboard Classic Series, 9:30 a.m.) May Aud., Simon Hall. For more Saturday, Oct. 20 "His Girl Friday." (Also Tues., Oct. 16, same info., call 889-5170. Friday, Oct. 12 times.) $3. Room 100 Brown Hall. 10 a.m. Performing Arts Dept and Book- 10:30 a.m. Woman's Club of WU Campus Noon. Dept. of Cell Biology and Physiology mark Society Lecture, "The Making of a Walking Tour. Meet at Brookings Arch. Tour Seminar, "Lipoprotein Lipase: Evolution, Tuesday, Oct. 16 Novel: Fact, Fake and Fiction," MacDonald conducted and narrated by trained members of Regulation, and Structure/Function Relation- 7 p.m. Dept of Asian and Near Eastern Harris, author of Hemingway's Suitcase. Woman's Club with emphasis on historical and ships," Clay Semenkovich, WU Dept. of Languages and Literatures Japanese Film Mallinckrodt Center Drama Studio, Room 208. architectural aspects of buildings. For reserva- Medicine. Cell Biology and Physiology Library, Series, "Yojimbo," Akira Kurosawa, director For more info., call 889-5400. tions or more info., call Sondra Ellis at 725-6316. 4th Fl., McDonnell Medical Sciences Bldg. (subtitled). Room 210 Ridgley Hall. Free. For more info., call 726-4449. 6:30 p.m. 137th Anniversary Founders Day 4:15 p-m. Dept of Philosophy Colloquium, Banquet featuring guest speaker William Satire, "Mental Causation," Fred Dretske, Dept. of Wednesday, Oct. 17 Pulitzer Prize-winning columnist. Adam's Mark Philosophy, Stanford U. Women's Bldg. Lounge. PERFORMANCES 7 and 9:30 p.m. Filmboard Foreign Series, Hotel, 4th and Chestnut streets. For reservations Monday, Oct. 15 "Red Sorghum," Chinese (subtitled). (Also or ticket information, call 889-5122. 3 p.m. Dept of Mathematics Q.C. Mappings Friday, Oct. 12 Thurs., Oct. 18, same times.) $3. Room 100 Thursday, Oct. 18 Brown Hall. Seminar, "Royden's Theorem," Richard 8 p.m. Edison Theatre "Stage Left" Series 10 a.nt-10 p.m. Performing Arts Dept Hosts Laugesen, WU grad. student. 199 Cupples I. Presents performance artist Branislav Tomich Friday, Oct.19 Hemingway Conference, "Ernest Hemingway: 4 p.m. Dept of Biology Seminar, "The NK doing his latest one-person work, "Love Guts." 7 and 9:30 p.m. Filmboard Feature Series, The Man and the Myth," featuring noted Homeobox Genes of Drosophila," Marshall W. (Also Sat., Oct. 13, at 8 and 10:30 p.m. The 8 "Working Girl." (Also Sat., Oct. 20, same times, Hemingway scholars Nina Baym, Donald Nirenberg, National Institutes of Health p.m. performances are sold out, but tickets are and Sun., Oct. 21, 7 p.m.) $3. Room 100 Brown. Junkins, Frank Laurence, Michael Reynolds and still available for the 10:30 p.m. show on Oct. Laboratory of Biochemical Genetics, Bethesda, Midnight Filmboard Midnight Series, Linda Wagner-Martin. (Also Oct. 19, 10 a.m.-lO 13.) Mallinckrodt Center Drama Studio, Room Md. Room 322 Rebstock Hall. For more info., "M'A'S'H." (Also Sat., Oct. 20, same time, and p.m., and Oct. 20, 10 a.m.-noon.) Edison 208. Cost: $10 for general public; $8 for senior call 889-6287. Sun., Oct. 21, 9:30 p.m.) $3. Room 100 Brown Theatre. Free admission to WU faculty, staff and citizens and WU faculty and staff; and $6 for Hall. On Fri. and Sat., both films can be seen for students. Cost for three-day event is $35; single Tuesday, Oct. 16 students. For more info., call 889-6543. a double feature price of $4; both Sun. films can day admission is $10. To register or for more 4 p.m. Dept of English and Committee on info., call 889-5858. Religious Studies Colloquium, "Doing Things Friday, Oct. 19 be seen for $4. With Metaphor or 'Can Feminists Call God 8 p.m. Performing Arts Dept Presents Friday, Oct. 19 'father?'" Janet Martin Soskice, University of Hemingway's "The Fifth Column." (Also on 5:45 p.m. HiUel Services. 6:30 p.m. Shabbat Cambridge Divinity School, and author, Sa^ Oct. 20, same time, and Sun., Oct. 21, at 2 Dinner. 8:30 p.m. Program: "In Our New Home: Metaphor and Religious Language. Hurst p.m. These shows are sold out. A fourth show \PORTS Entering Freedom." 6300 Forsyth Blvd. For more Lounge, Duncker Hall. For info., call 889-5115. has been added on Oct. 21 at 7 p.m.) info., call 726-6177. 4 p.m. Dept of Chemistry Seminar, Mallinckrodt Center Drama Studio, Room 208. Saturday, Oct. 13 "Dynamic NMR Studies and Stereochemical Cost: $7 for general public; $5 for senior 11 a.m. Men and Women's Cross Country. Behavior of Octahedral Transition Metal citizens, WU faculty and staff, and all students. WU/Army ROTC Invitational. Bushyhead Track. For ticket info., call 889-6543. Complexes of Group XTV Metalloles," E. 5:30 p.m. Women's Soccer. WU Tournament. Calendar Deadline Colomer, prof., Institut de Chimie Fine DePauw University vs. Millsaps College. At 7:30 The deadline to submit items for the Oct. 18-27 Universite des Sciences et Techniques du p.m., WU vs. Trinity University. On Sun., Oct. calendar of the Washington University Record is Languedac, Montpelier, France. Room 311 14, consolation match at 11 a.m., championship Oct. 12. Items must be typed and state time, McMillen. For more info., call 889-6530. MUSIC match at 1 p.m. Francis Field. date, place, nature of event, sponsor and 4 p.m. Dept of Mathematics Analysis Saturday, Oct. 13 Monday, Oct. 15 admission cost. Incomplete items will not be Seminar, "Harmonic Analysis of Domains," Der printed. If available, include speaker's name and 7:30 p.m. Men's Junior Varsity Soccer. WU Chen Chang, prof., University of Maryland. 7:30 p.m. Dept of Music Piano Recital identification and the title of the event; also vs. Principia. Francis Field. Room 199 Cupples I. featuring pianist John Cornelius has been include your name and telephone number. Send 7:30 p.m. WU Asian Art Society Presents canceled. Thursday, Oct. 18 items to calendar editor, Box 1070, or by Video/Lecture, "China's Fifth Generation of Sunday, Oct. 14 4 p.m. Men's Junior Varsity Soccer. WU vs. electronic mail to p72245SS at WUVMC. Filmmakers," Robert E. Hegel, WU prof, of 4 p.m. Depts. of Music and German Present Concordia. Francis Field. Chinese and chair of Dept. of Asian and Near a Liederabend featuring mezzo-soprano Mary Eastern Languages and Literatures. Room 100 Henderson, pianist Karen Laubengayer, and Busch Hall. For more info., call 889-5156. guitarist Rodney Stucky. Steinberg Hall Aud. For Wednesday, Oct. 17 more info., call 889-5574. 11 a.m. Assembly Series Lecture in Conjunc- 7:30 p.m. Dept of Music Presents University Genome center """ continued from p. 1 tion With Hemingway Conference, City Symphony Orchestra Concert, with David D. Chaplin, M.D., Ph.D., "Hemingway for Our Time," Michael Reynolds, William Schatzkamer, conductor. Graham adrenal gland, fragile X syndrome, author, Hemingway: The Paris Years. Edison Chapel. For more info., call 889-5574. assistant professor of genetics. and color blindness are located on the The other two projects have as X chromosome. Theatre. For more info., call 889-4620. Saturday, Oct. 20 4 p.m. Dept of Mathematics Analysis their goals detailed maps of two The University's Center for 2 p.m. Edison Theatre "ovations! for young Seminar, "Zeros of Polynomials and Non- human chromosomes, those known as Genetics in Medicine — already people" Series Presents Paul Winter Consort. negativity of coefficients," Roger Barnard, Texas Edison Theatre. Cost: $7. For ticket info., call seven and X. The maps will establish involved in organizing the world's first Tech. Room 199 Cupples I. 889-6543. "guideposts" in the expanse of DNA, complete collection of YACs, screen- 4:15 p.m. Dept of Biochemistry and 8 p.m. Edison Theatre "OVATIONS!" Series making it easier for researchers to find ing them and sharing them with Molecular Biophysics Seminar, "Recognition Presents Paul Winter Consort. Edison Theatre. their way to genes of interest. Leading investigators elsewhere — was of Transfer RNA Studied With Dissected RNA Cost: $18 for general public; $14 for senior and Protein Molecules," Paul R. Schimmel, Dept. the project with Schlessinger are co- instrumental in bringing one of the citizens and WU faculty and staff; and $9 for of Biology, MIT. Erlanger Aud., 1st FL, principal investigators Helen Donis- genome initiative's first centers of students. For ticket info., call 889-6543. McDonnell Medical Sciences Bldg. Keller, Ph.D., professor of genetics, investigation to Washington Univer- 8 p.m. Dept of Romance Languages and and Philip P. Green, Ph.D., assistant sity, Schlessinger says. "We have a Literatures Second Annual John L. Grigsby professor of genetics, both experts on fully organized genetics research Memorial Lecture, "Roland and the Rolands: EXHIBITIONS human genetics and gene-mapping, center here, with a sustained supply Texts and the Text," Joseph Duggan, prof., and Olson, the developer of YACs and of resources, space and facilities University of California, Berkeley. Women's associated technology. Bldg. Lounge. For more info., call 889-5180. "Bookness: Artists' Explorations of Form developed by the School of Medicine, and Content," including "artists' books" by Approximately 104 genes are the McDonnell Foundation, the Thursday, Oct. 18 John Cage, Andy Warhol and local artist Leila already known to reside on chromo- Howard Hughes Medical Institute, and 1:10 p.m. George Warren Brown School of Daw. Gallery of Art, Steinberg Hall, lower some 7, which is believed to contain a the Biomedical Agreement with Social Work Fall Lecture Series, presents a gallery. Through Dec. 2. 10 a.m.-5 p.m. weekdays; 1-5 p.m. weekends. total of about 5,000 genes. Several of Monsanto, in conjunction with federal panel discussion on "Women in the Corporate these, including the cystic fibrosis funding," he says. World: Career Management Paths," Carol "Modern Fine Printing: The Black Art" Caruthers, moderator, Price Waterhouse; Features books published over the last century gene and those that control the Other medical schools receiving Cynthia Heath, Emerson Electric Co.; Martha that show examples of fine printing. Through immune response, are involved in grants are at the University of Califor- Perine, Federal Reserve Bank of St. Louis; and Oct. 14. Special Collections, Olin Library, Level disease. The role of the X chromo- nia at San Francisco, the University of Julie Westerman, Fleishman-Hillard Inc. Brown 5. 8:30 a.m.-5 p.m. weekdays. some in human disease has also made Michigan and the Massachusetts Hall Lounge. For more info., call 889-6606. "Hemingway and Popular Culture." Oct. 15 it the target of ardent study. Genes for Institute of Technology. through Jan. 15, 1991. Special Collections, Olin hemophilia A and B, diseases of the Library, Level 5. 8:30 a.m. to 5 p.m. weekdays.