Modern Fungicides and Antifungal Compounds VI
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Full Screen View
Photodegradation of 2-Substituted Benzimidazole Fungicides by Ultraviolet Radiation by Dong Chen A Thesis Submitted to the Faculty of The College of Science in Partial Fulfillment of the Requirements for the Degree of Master of Science Florida Atlantic University Boca Raton, Florida August 1994 PHOTODEGRADATION OF 2-SUBSTITUTED BENZIMIDAZOLE FUNGICIDES BY ULTRAVIOLET RADIATION BY DONG CHEN This thesis was prepared under the direction of the candidate's thesis advisor, Dr.Cyril Parkanyi, Department of Chemistry, and has been approved by the members of the supervisory committee. It was submitted to the faculty of the College of Science and was accepted in partial fulfillment of the requirements for the degree of Master of Science in Chemistry. SUPERVISORY COMMITTEE Thesis Advisor Chairman, Department of Chemistry D an, College of Sc1ence I I Date II Acknowledgments I wish to express my sincere thanks to my thesis advisor, Dr. Cyril Parkanyi, Professor and Chairman of the Department of Chemistry, for his guidance, suggestions and enthusiastic support. His patience and keen interest throughout this study are greatly appreciated. I would also like to acknowledge the valuable suggestions of my committe members Dr. Russell G. Kerr, Assistant Professor, and Dr. Earl W Baker, Professor, Department of Chemistry. Special thanks are due to my dear friend and colleague, Ms. Guoping Deng, for her constant support and help with NMR data. I am most grateful to Dr. J William Louda for the mass spectra, without his help this work would not have been completed. My deepest and sincerest thanks go to my parents, Mrs. & Mr. Chen, for their love, encouragement and support. -
FRAC Code List ©*2020: Fungal Control Agents Sorted by Cross Resistance Pattern and Mode of Action (Including FRAC Code Numbering)
FRAC Code List ©*2020: Fungal control agents sorted by cross resistance pattern and mode of action (including FRAC Code numbering) Disclaimer The technical information contained in the global guidelines/the website/the publication/the minutes is provided to CropLife International/RAC members, non-members, the scientific community and a broader public audience. While CropLife International and the RACs make every effort to present accurate and reliable information in the guidelines, CropLife International and the RACs do not guarantee the accuracy, completeness, efficacy, timeliness, or correct sequencing of such information. CropLife International and the RACs assume no responsibility for consequences resulting from the use of their information, or in any respect for the content of such information, including but not limited to errors or omissions, the accuracy or reasonableness of factual or scientific assumptions, studies or conclusions. Inclusion of active ingredients and products on the RAC Code Lists is based on scientific evaluation of their modes of action; it does not provide any kind of testimonial for the use of a product or a judgment on efficacy. CropLife International and the RACs are not responsible for, and expressly disclaim all liability for, damages of any kind arising out of use, reference to, or reliance on information provided in the guidelines. Listing of chemical classes or modes of action in any of the CropLife International/RAC recommendations must not be interpreted as approval for use of a compound in a given country. Prior to implementation, each user must determine the current registration status in the country of use and strictly adhere to the uses and instructions approved in that country. -
Clinical Epidemiology and Treatment Outcome of Hexaconazole Poisoning – a Prospective Six Year Study
Hexaconazole - Clinical epidemiology and treatment outcome A. Anand & P. Abinash ORIGINAL ARTICLE ORIGINAL ARTICLE Clinical epidemiology and treatment outcome of Hexaconazole poisoning – A prospective six year study ACHARYA ANAND1 and PANDA ABINASH2 1Department of Pharmacology, Konaseema Institute of Medical Sciences & Research Foundation, Amalapuram, Andhra Pradesh, India 2Department of Pharmacology, M.K.C.G. Medical College, Berhampur, Odisha, India. Abstract Background: Hexaconazole is a category 3/4 of poison as per the W.H.O Expert Group on Pesticide Residues. Hexaconazole is used to control infection by fungi in paddy and other crops. Apart from destroying the target species, it can also cause damage to humans. There have been discrete reports of instances of human poisoning due to hexaconazole. Methodology: A patient record-based cross-sectional study was carried out in Konaseema Institute of Medical Science & Research Foundation, Amalapuram, Andhra Pradesh, India during a period from March 2014 to April 2020 on 26 confirmed cases of hexaconazole poisoning. The clinic-demographic data, hematological, and biochemical parameters at the time of admission and at 72 hrs as well as the outcome were recorded and analyzed using descriptive statistics and paired t test. Result: The prevalence of hexaconazole poisoning was 4.79% of all poisoning cases. The major clinical presentation was gastrointestinal symptoms with vomiting being commonest. There was no significant change in the biochemical and hematological parameters. The mean duration of hospitalization was 4.93+1.39 days. The recovery rate was 100% without any major sequel. Conclusion: Poisoning due to hexaconazole is uncommon in comparison to poisoning by other pesticides in the agricultural community. -
Pesticide Composition Potentiated in Efficacy and Method for Potentiating the Efficacy of Pesticidal Active Ingredients
(19) & (11) EP 2 183 968 A1 (12) EUROPEAN PATENT APPLICATION published in accordance with Art. 153(4) EPC (43) Date of publication: (51) Int Cl.: 12.05.2010 Bulletin 2010/19 A01N 25/00 (2006.01) A01N 25/30 (2006.01) A01N 25/32 (2006.01) A01N 31/14 (2006.01) (2006.01) (2006.01) (21) Application number: 08828276.9 A01N 35/10 A01N 47/34 A01N 47/40 (2006.01) A01P 7/04 (2006.01) (22) Date of filing: 25.08.2008 (86) International application number: PCT/JP2008/065101 (87) International publication number: WO 2009/028454 (05.03.2009 Gazette 2009/10) (84) Designated Contracting States: (72) Inventors: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR • DAIRIKI, Hiroshi HR HU IE IS IT LI LT LU LV MC MT NL NO PL PT Makinohara-shi RO SE SI SK TR Shizuoka 421-0412 (JP) Designated Extension States: • NAKAMURA, Rieko AL BA MK RS Makinohara-shi Shizuoka 421-0412 (JP) (30) Priority: 31.08.2007 JP 2007226839 (74) Representative: Cabinet Plasseraud (71) Applicant: Nippon Soda Co., Ltd. 52, rue de la Victoire Tokyo 100-8165 (JP) 75440 Paris Cedex 09 (FR) (54) PESTICIDE COMPOSITION POTENTIATED IN EFFICACY AND METHOD FOR POTENTIATING THE EFFICACY OF PESTICIDAL ACTIVE INGREDIENTS (57) The present invention provides a pesticide composition comprising a pesticidal active ingredient and a compound represented by chemical formula (I) or chemical formula (II) R-O-(EO)w-(PO)x-(EO)y-(PO)z-H (I) R-O-(PO)w-(EO)x-(PO)y-(EO)z-H (II) (wherein, EO represents an ethyleneoxy group, PO represents a propyleneoxy group, R represents an alkyl or alkenyl group having 8 to 20 carbons, w represents on average an integer in the range of 1 to 25, x represents on average an integer in the range of 1 to 25, y represents on average an integer in the range of 1 to 25, and z represents on average an integer in the range of 1 to 25). -
Frac List of Fungicide Common Names - 2016
FRAC LIST OF FUNGICIDE COMMON NAMES - 2016 The Common Names, MOA Code, FRAC Code and Chemical Group names included in this list are those used in the FRAC Code List and the associated List of Plant Pathogenic Organisms Resistant to Disease Control Agents. Common Name MOA Code FRAC Chemical Group Code Acibenzolar-S- P1: benzo-thiadiazole BTH P benzo-thiadiazole BTH methyl Aldimorph G2: Amines (morpholines) 5 morpholine SBI Class II Ametoctradin C8: QxI 45 triazolo-pyrimidylamine Amisulbrom C4: QiI 21 sulfamoyl-triazole Anilazine Multi-site: triazine M8 triazine Azaconazole G1: DMI (SBI class 1) 3 triazole Azoxystrobin C3: QoI 11 methoxy-acrylates Bacillus F6: Microbial 44 microbial disrupters of pathogen cell amyloliquefaciens membranes strain D747 Bacillus F6: Microbial 44 microbial disrupters of pathogen cell amyloliquefaciens membranes strain MBI600 Bacillus subtilis F6: Microbial 44 microbial disrupters of pathogen cell strain QST713 membranes Bacillus subtilis F6: Microbial 44 microbial disrupters of pathogen cell strain FZB24 membranes Benalaxyl A1: Phenylamide 4 acylalanine Benalaxyl-M A1: Phenylamide 4 acylalanine (kiralaxyl) Benodanil C2: SDHI 7 phenyl-benzamide Benomyl B1: MBC 1 benzimidazole Benthiavalicarb H5: CAA fungicides 40 valinamide carbamates Benzovindiflupyr C2: SDHI 7 Pyrazole-carboxamide Binapacryl C5 29 dinitrophenyl crotonate Biphenyl F3: AH fungicides 14 aromatic hydrocarbons Bitertanol G1: DMI (SBI class 1) 3 triazole Bixafen C2: SDHI 7 Pyrazole-carboxamide Blasticidin-S D2: enopyranuronic acid 23 enopyranuronic -
Antifungal Drugs Are Those Drugs Which Inhibit Or Retard Fungal Growth
Prepared by- Dr Arpita Shrivastav DR ARPITA SHRIVASTAV ASSTT. PROFESSOR VETERINARY COLLEGE REWA Antifungal drugs are those drugs which inhibit or retard fungal growth. DR ARPITA SHRIVASTAV ASSTT. PROFESSOR VETERINARY COLLEGE REWA Sites of action of antifungal drugs Chitin + Glucan DR ARPITA SHRIVASTAV ASSTT. PROFESSOR VETERINARY COLLEGE REWA SITE OF ACTION DRUGS Cell membrane Ergosterol binding Amphotericin B, Natamycin and Nystatin Ergosterole synthesis inhibitors Allylamines (Amorolfine, (Squalene epoxidase inhibitor) Terbinafine etc.) Ergosterol synthesis inhibitors Azoles (Ketoconazole, Miconazole (lanosterol to ergosterol) etc.) Cell wall β glucan synthase inhibitor Echinocandins Intracelluler Pyrimidine analogue Flucytosine Mitotic inhibitors Gresiofulvin Other site Benzoic acid , salicylic acid, tolnaftate, castor oil etc. DR ARPITA SHRIVASTAV ASSTT. PROFESSOR VETERINARY COLLEGE REWA Source – Streptomyces nodosus Mechanism of action – Increases permeability of cell membrane by binding to ergosterol Antimicrobial spectrum – broad spectrum Resistance – when less ergosterol in membrane Pharmacokinetics – poorly absorbed from GIT, do not cross BBB Adverse effects - Nephrotoxicity Drug interaction – 1. with miconazole antagonistic effect 2. with flucytosine synergistic effect Dose – Dog -0.25 to 0.50 mg/kg, 3 times weekly Cat – 0.1 to 0.50 mg/kg, 3 times weekly DR ARPITA SHRIVASTAV ASSTT. PROFESSOR VETERINARY COLLEGE REWA DR ARPITA SHRIVASTAV ASSTT. PROFESSOR VETERINARY COLLEGE REWA Source – Streptomyces noursie Streptomyces aureus Mechanism of action – It binds to ergosteol and forms pores in cell membrane DR ARPITA SHRIVASTAV ASSTT. PROFESSOR VETERINARY COLLEGE REWA Source - Streptomyces natalensis Mechanism of action – Binds to ergosterol and cause leakiness of cell membrane DR ARPITA SHRIVASTAV ASSTT. PROFESSOR VETERINARY COLLEGE REWA Pentameric ring compounds containing at least one other non-carbon atom of either nitrogen, sulfur, or oxygen. -
Application of Multiresidue Procedures in Pesticides Residues Analysis
Pure & App!. Chem., Vol. 58, No. 7, pp. 1035—1062, 1986. Printed in Great Britain. © 1986 IUPAC INTERNATIONALUNION OF PURE AND APPLIED CHEMISTRY APPLIED CHEMISTRY DIVISION COMMISSION ON PESTICIDE CHEMISTRY* IUPAC Reports on Pesticides (21) APPLICATION OF MULTIRESIDUE PROCEDURES IN PESTICIDES RESIDUES ANALYSIS Prepared for publication by A. AMBRUS1 and H-P. THIER2 'Mezogazdasagi és ElelmezesUgyi Miniszterium, Novenyvedelmi és Agrokemiai Kozpont, Budapest, Hungary 2lnstitut für Lebensmittelchemie der Universität Münster, FRG *Membership of the Commission during the preparation of this report (1983—85) was as follows: Chairman: J. A. R. Bates (UK); Secretary: R. Greenhalgh (Canada); Titular Members: N. Aharonson (Israel); A. Ambrus (Hungary); S. Gorbach (FRG); W. Klein (FRG); Associate Members: J. Desmoras (France); H. 0. Esser (Switzerland); L. A. Golovleva (USSR); R. J. Hemingway (UK); R. Hollingworth (USA); N. Kurihara (Japan); W. B. Neely (USA); S. Otto (FRG); T. R. Roberts (UK); J. Seiber (USA); D. B. Sharp (USA); J. W. Vonk (Netherlands); National Representatives: A. M. P. D'Angelo (Argentina); W. Lara (Brazil); Zhengming Li (Chinese Chemical Society); J. Kovacicova (Czechoslovakia); N. Drescher (FRG); F. Dutka (Hungary); S. K. Mukerjee (India); P. Bracha (Israel); J. Miyamoto (Japan); C. K. Heng (Malaysia); G. W. Mason (New Zealand); A. Kotarski (Poland); N. Bärbulescu (Romania); P. C. Kearney (USA). Correspondence on the report should be addressed to the Secretary (1985—89) of the Commis- sion: Dr. T. R. Roberts, Shell Research Ltd., Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AG, UK. Republication of this report is permitted without the need for formal IUPAC permission on condition that an acknowledgement, with full reference together with IUPAC copyright symbol (© 1986 IUPAC), is printed. -
Title Α-Chlorocarbonyl Compounds : Their Synthesis and Applications
α-Chlorocarbonyl Compounds : Their Synthesis and Title Applications (Commemoration Issue Dedicated to Professor Shigeo Tanimoto On the Occation of His Retirement) Author(s) Terao, Keiji Bulletin of the Institute for Chemical Research, Kyoto Citation University (1992), 70(3): 338-377 Issue Date 1992-10-30 URL http://hdl.handle.net/2433/77455 Right Type Departmental Bulletin Paper Textversion publisher Kyoto University Bull. Inst. Chem.Res., Kyoto Univ., Vol. 70,No. 3 , 1992 REVIEW a-Chlorocarbonyl Compounds Their Synthesis and Applications---------- Keiji TERAO* ReceivedJuly 16, 1992 KEY WORDS : a—Chlorocarbonyl compounds / Thiazoles / Pyrroles / Furans / Pyrimidines / Oxazoles / Pyrazoles 1. Introduction a—Chlorocarbonyl compounds are very useful starting materials for indutrial scale production of various agrochemicals, pharmaceuticals, dyestuffs and polymers because of their highly reactive multifunctional character through the symergism of carbonyl group and chlorine atom. Their chemical reactions can basically be classi- fied as shown in Scheme 1. Scheme 1 Nucleophilic addition 1 Ri - © - CR2 - ©—• Nucleophilic substitution II 1 O ©of the chlorine atom Electrophilic substitution R1, R2 = low alkyl, H, CO2R, etc. R = alkyl * .~~: Wacker Chemicals East Asia Ltd ., 14 —1 Nishi—waseda 2 —chome, Shinjuku—ku, Tokyo 169 (338) l a-Chlorocarbonyl Compoundsfor Industry (a) Electrophilic substitution of hydrogen The hydrogen atom is strongly activated by the inductive effect of the car- bonyl group as well as the chlorine atom and is very susceptible to an electro- philic substitution. (b) Nucleophilic substitution of the chlorine atom The chlorine atom can be replaced quite readily by nucleophilic agents be- cause of the strong inductive effect of the carbonyl group. (c) Nucleophilic addition to the carbonyl group Additional positive polarization of the C atom of the carbonyl group takes place with the aid of a-chlorine atom leading to a facile addition of nucleophilic agents (Scheme 2 ). -
Group of Fungicides
DEPARTMENT OF PLANT PATHOLOGY UNDER GRADUATE EDUCATION PAT 201 PRINCIPLES OF CROP DISEASE MANAGEMENT (1+1) COURSE TEACHER Dr. V. PRAKASAM PROFOESSOR (PLANT PATHOLOGY) SYLLABUS THEORY Principles of Crop disease management –– Epidemiology of crop diseases – Disease surveillance, assessment of disease intensity - forecasting. Survival and mode of spread of plant pathogens – Types of resistance – Cross protection – mechanism of resistance,. Methods and management of plant diseases - Fungicides – Characteristics of an ideal fungicide - Classification – groups of fungicides – antibiotics. Formulations – compatibility. Phytotoxicity – precautions and safety measures in handling. Management of diseases – seed, soil foliar and post harvest diseases – seed health testing methods – Simple diagnostic techniques for identification of diseases. Biological control and their scope – biocontrol agents – Fungi, bacteria, vesicular arbuscular mycorrhizae – Plant products and antiviral principles. Biotechnological approaches in plant disease management. PRACTICAL Various groups of fungicides and antibiotics – Preparation of Bordeaux mixture and Bordeaux paste – Preparation of fungicidal spray solution – methods of application - seed treatment – Soil and foliar application –– demonstration of Phytotoxicity – Production of immunized seedlings in citrus – Biological control agents- Trichoderma, Pseudomonas and vesicular arbuscular mycorrhizae - Methods of mass production and application. Preparation of botanicals – leaf extracts, oil emulsions and anti viral -
(12) United States Patent (10) Patent No.: US 8,110,689 B2 Wada Et Al
US008110689B2 (12) United States Patent (10) Patent No.: US 8,110,689 B2 Wada et al. (45) Date of Patent: *Feb. 7, 2012 (54) BENZANILIDES WITH INSECTICIDAL M. Waksmundzka-Hajnos, “Chromatographic Separation of Nitro ACTIVITY Phenones and Their Reduced Derivatives on Thin Layers of Polar Adsorbents”, XP-008069069, pp. 159-171. Jun-Ichi Inoh et al., “Palladium-Catalyzed Coupling Reaction of (75) Inventors: Katsuaki Wada, Tochigi (JP); Tetsuya 4-Alkylnitrobenzenes with Aryl Bromides at Their Benzylic Posi Murata, Tochigi (JP); Katsuhiko tion”, XP-004130892, Tetrahedron Letters, 1998, pp. 4673-4676. Shibuya, Tochigi (JP); Eiichi Shimojo, M. Makosza et al., “Synthesis of (p-Nitroaryl)diarylmethanes via Vicarious Nucleophilic Substitution of Hydrogen', XP-002399354. Tochigi (JP) Synthesis, No. 9, 2000, pp. 1237-1240. S. Florio et al., “Vicarious Nucleophilic Substitution of (73) Assignee: Bayer Cropsciene AG, Monheim (DE) (Chloroalkyl)heterocycles with Nitroarenes', XP-002399353, Eur, J. Org. Chem., 2004, pp. 2118-2124. (*) Notice: Subject to any disclaimer, the term of this W. Waiers, “Some Substitution Reactions of patent is extended or adjusted under 35 4-Aminodiphenylmethane', XP-008069039, pp. 1060-1064. G. Esselen, Jr., “The Splitting of Benzhydrols by the Action of Bro U.S.C. 154(b) by 403 days. mine”, XP-002399352, pp. 308-324. This patent is Subject to a terminal dis M.Z.A. Badr et al., “Molecular Rearrangements. 14. Photolysis and claimer. Thermolysis of Phenylpropionanilides”, XP-0023993.51, J. Org. Chem., vol. 44, No. 18, 1979, pp. 3244-3247. Y. Watanabe et al., “Stilbene Derivative. Its Preparation, and (21) Appl. No.: 11/917,411 Electrophotographic Photoreceptor Using Same', XP-002399363, 2000, 2 pgs. -
The ARS Pesticide Properties Database
Crop Systems & Global Change Products and Services Page 1 of 1 Beltsville Beltsville Agricultural Rsch. Ctr. Crop Systems & Global Change Printable Version E-mail this page You are here: Products & Services / Database Files / Pesticide Properties Database Enter Keywords This site only Advanced Search Pesticide Properties DataBase ARS Products & Services Links ARS Products & Services PPDB TEKTRAN The ARS Pesticide Properties Database Introduction Description Publications Coden List Full Text Publications Units (.pdf) Pesticide list Public Databases and Combined File Programs (lists all pesticides. Takes ARS Cotton Database several minutes BARC Weather Stations to display) Pesticide Properties Database Technical Contact: Dennis Timlin. CSGCL, 301-504- 6255 [email protected] Last Modified: 11/06/2009 ARS Home | USDA.gov | Site Map | Policies and Links FOIA | Accessibility Statement | Privacy Policy | Nondiscrimination Statement | Information Quality | USA.gov | White House http://www.ars.usda.gov/services/docs.htm?docid=14199 2/27/2013 Crop Systems & Global Change Products and Services Page 1 of 19 Beltsville Beltsville Agricultural Rsch. Ctr. Crop Systems & Global Change Printable Version E-mail this page You are here: Products & Services / Enter Keywords This site only Advanced Search Coden List ARS Products & Services Links ARS Products & Services 1800AJ TEKTRAN V.H.FREED, "CHEMISTRY OF HERBICIDES & PESTICIDES AND THEIR EFFECTS ON SOIL & WATER", SOIL SCIENCE Publications SOCIETY OF Full Text Publications (.pdf) Public Databases and Programs 5OLSEN OLSEN, L.D., ROMAN-MAS, A., WEISSKOPF, C.P., AND KLAINE, S.J. "TRANSPORT AND DEGRADATION OF ALDICARB IN THE SOIL PROFILE:---", PROC. 1994 AWRA NAT. SYMP. WATER QUALITY, 1994, 6ABERN ABERNATHY, J.R. "LINURON, CHLORBROMURON, NITROFEN & FLUBRODIFEN ADSORPTION AND MOVEMENT IN TWELVE SELECTED OF 6ACSAR AMERICAN CHEMICAL SOCIETY, WASH., D.C., "ARSENICAL PESTICIDE". -
Emerging Contaminants in Groundwater
Emerging contaminants in groundwater Groundwater Science Programme Open Report OR/11/013 O = H2–CH2–P–OH _ OH BRITISH GEOLOGICAL SURVEY GROUNDWATER SCIENCE PROGRAMME OPEN REPORT OR/11/013 Emerging contaminants in groundwater The National Grid and other Ordnance Survey data are used with the permission of the Controller of Her Majesty’s M E Stuart, K Manamsa, J C Talbot and E J Crane Stationery Office. Licence No:100017897/2011. Keywords Report; groundwater; organic micropollutants; pesticides, pesticide metabolites, pharmaceuticals; veterinary medecines; risk assessment. Front cover Structures of selected polar organic micropollutants: bisphenol A, clopyralid, carbamazepine, estradiol, glyphosate metabolite AMPA, metaldehyde, sulfamethoxazole, Bibliographical reference STUART ME, MANAMSA K, TALBOT J C AND CRANE E J. 2011. Emerging contaminants in groundwater. British Geological Survey Open Report, OR/11/013. 123pp. Copyright in materials derived from the British Geological Survey’s work is owned by the Natural Environment Research Council (NERC) and/or the authority that commissioned the work. You may not copy or adapt this publication without first obtaining permission. Contact the BGS Intellectual Property Rights Section, British Geological Survey, Keyworth, e-mail [email protected]. You may quote extracts of a reasonable length without prior permission, provided a full acknowledgement is given of the source of the extract. Maps and diagrams in this book use topography based on Ordnance Survey mapping. © NERC 2011. All rights reserved Keyworth, Nottingham British Geological Survey 2011 BRITISH GEOLOGICAL SURVEY The full range of our publications is available from BGS shops at British Geological Survey offices Nottingham, Edinburgh, London and Cardiff (Welsh publications only) see contact details below or shop online at www.geologyshop.com BGS Central Enquiries Desk 0115 936 3143 Fax 0115 936 3276 The London Information Office also maintains a reference email [email protected] collection of BGS publications including maps for consultation.