Use of High Throughput Assays and Computational Tools; Endocrine Disruptor Screening Program; Notice of Availability and Opportunity for Comment’’
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A Monitoring of Allantoin, Uric Acid, and Malondialdehyde Levels In
A Monitoring of Allantoin, Uric Acid, and Malondialdehyde Levels in Plasma and Erythrocytes after a 10-Minute Running Activity ROMAN KANĎÁR, XENIE ŠTRAMOVÁ, PETRA DRÁBKOVÁ, JANA KŘENKOVÁ Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Pardubice, Czech Republic A running title: Allantoin and Uric Acid Levels after Running Activity Correspondence to: Roman Kanďár, Ph.D., Department of Biological and Biochemical Sciences, Faculty of Chemical Technology, University of Pardubice, Studentska 573, 532 10 Pardubice, Czech Republic Tel.: +420 466037714 Fax: +420 466037068 E-mail: [email protected] Keywords: allantoin, uric acid, oxidative stress, antioxidants, short-term intense exercise 1 Summary Uric acid is the final product of human purine metabolism. It was pointed out that this compound acts as an antioxidant and is able to react with reactive oxygen species forming allantoin. Therefore, the measurement of allantoin levels may be used for the determination of oxidative stress in humans. The aim of the study was to clarify the antioxidant effect of uric acid during intense exercise. Whole blood samples were obtained from a group of healthy subjects. Allantoin, uric acid, and malondialdehyde levels in plasma and erythrocytes were measured using a HPLC with UV/Vis detection. Statistical significant differences in allantoin and uric acid levels during short-term intense exercise were found. Immediately after intense exercise, the plasma allantoin levels increased on the average of two hundred per cent in comparison to baseline. Plasma uric acid levels increased slowly, at an average of twenty per cent. On the other hand, there were no significant changes in plasma malondialdehyde. -
Retention Indices for Frequently Reported Compounds of Plant Essential Oils
Retention Indices for Frequently Reported Compounds of Plant Essential Oils V. I. Babushok,a) P. J. Linstrom, and I. G. Zenkevichb) National Institute of Standards and Technology, Gaithersburg, Maryland 20899, USA (Received 1 August 2011; accepted 27 September 2011; published online 29 November 2011) Gas chromatographic retention indices were evaluated for 505 frequently reported plant essential oil components using a large retention index database. Retention data are presented for three types of commonly used stationary phases: dimethyl silicone (nonpolar), dimethyl sili- cone with 5% phenyl groups (slightly polar), and polyethylene glycol (polar) stationary phases. The evaluations are based on the treatment of multiple measurements with the number of data records ranging from about 5 to 800 per compound. Data analysis was limited to temperature programmed conditions. The data reported include the average and median values of retention index with standard deviations and confidence intervals. VC 2011 by the U.S. Secretary of Commerce on behalf of the United States. All rights reserved. [doi:10.1063/1.3653552] Key words: essential oils; gas chromatography; Kova´ts indices; linear indices; retention indices; identification; flavor; olfaction. CONTENTS 1. Introduction The practical applications of plant essential oils are very 1. Introduction................................ 1 diverse. They are used for the production of food, drugs, per- fumes, aromatherapy, and many other applications.1–4 The 2. Retention Indices ........................... 2 need for identification of essential oil components ranges 3. Retention Data Presentation and Discussion . 2 from product quality control to basic research. The identifi- 4. Summary.................................. 45 cation of unknown compounds remains a complex problem, in spite of great progress made in analytical techniques over 5. -
Allantoin-Hydrolyzed Animal Protein Product
Patentamt JEuropaischesEuropean Patent Office ® Publication number: 0 087 374 Office européen des brevets B1 (Î2) EUROPEAN PATENT SPECIFICATION (45) Dateof publication of patent spécification: 27.05.87 ® Int. Cl.4: A 23 J 3/00, A 61 K 7/48 (§) Application number: 83400376.6 (22) Date of filing: 23.02.83 (54) Allantoin-hydrolyzed animal protein product. (30) Priority: 24.02.82 US 351722 (73) Proprietor: CHARLES OF THE RITZ GROUP LTD. 01.06.82 US 383404 40 West 57th Street 13.12.82 US 449117 New York, NY 10019 (US) (§) Dateof publication of application: (72) Inventor: Puchalski, Eugène 31.08.83 Bulletin 83/35 129 McAdoo Avenue Jersey City New Jersey (US) Inventor: Deckner, George E. (§) Publication of the grant of the patent: 645 Horst Street 27.05.87 Bulletin 87/22 Westfield New Jersey (US) Inventor: Dixon, Richard P. 23 Avondale Lane (§) Designated Contracting States: Aberdeen New Jersey (US) AT BE CH DE FR GB IT Ll LU NL SE Inventor: Donahue, Frances A. 2 Kimberley Court Apt. 16 Middletown New Jersey (US) (58) Références cited: FR-A-2510 563 Y- US-A-3 941722 (74) Représentative: Maiffret, Bernard et al Cû Law Offices of William J. Rezac 49, avenue SOAP, PERFUMERY AND COSMETICS, vol. 49, Franklin D. Roosevelt no. 11, November 1976, pages 481-485. S. B. F-75008 Paris (FR) ^ MECCA: "Uric acid, allantoin and allantoin ^ derivatives" SE1FEN- OLE - FETTE - WACHSE, vol. 97, no. 15, N 1971, pages 533-534. S. B. MECCA: "Neue 00 Allantoin-Derivate fur die kosmetische und O dermatologische Anwendung" C9 Note: Within nine months from the publication of t\the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposopposition to the European patent granted. -
Transport of Dangerous Goods
ST/SG/AC.10/1/Rev.16 (Vol.I) Recommendations on the TRANSPORT OF DANGEROUS GOODS Model Regulations Volume I Sixteenth revised edition UNITED NATIONS New York and Geneva, 2009 NOTE The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the United Nations concerning the legal status of any country, territory, city or area, or of its authorities, or concerning the delimitation of its frontiers or boundaries. ST/SG/AC.10/1/Rev.16 (Vol.I) Copyright © United Nations, 2009 All rights reserved. No part of this publication may, for sales purposes, be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, electrostatic, magnetic tape, mechanical, photocopying or otherwise, without prior permission in writing from the United Nations. UNITED NATIONS Sales No. E.09.VIII.2 ISBN 978-92-1-139136-7 (complete set of two volumes) ISSN 1014-5753 Volumes I and II not to be sold separately FOREWORD The Recommendations on the Transport of Dangerous Goods are addressed to governments and to the international organizations concerned with safety in the transport of dangerous goods. The first version, prepared by the United Nations Economic and Social Council's Committee of Experts on the Transport of Dangerous Goods, was published in 1956 (ST/ECA/43-E/CN.2/170). In response to developments in technology and the changing needs of users, they have been regularly amended and updated at succeeding sessions of the Committee of Experts pursuant to Resolution 645 G (XXIII) of 26 April 1957 of the Economic and Social Council and subsequent resolutions. -
Safety Assessment of Benzyl Salicylate As Used in Cosmetics
Safety Assessment of Benzyl Salicylate As Used in Cosmetics Status: Draft Report for Panel Review Release Date: November 9, 2018 Panel Meeting Date: December 3-4, 2018 The 2018 Cosmetic Ingredient Review Expert Panel members are: Chair, Wilma F. Bergfeld, M.D., F.A.C.P.; Donald V. Belsito, M.D.; Ronald A. Hill, Ph.D.; Curtis D. Klaassen, Ph.D.; Daniel C. Liebler, Ph.D.; James G. Marks, Jr., M.D., Ronald C. Shank, Ph.D.; Thomas J. Slaga, Ph.D.; and Paul W. Snyder, D.V.M., Ph.D. The CIR Executive Director is Bart Heldreth, Ph.D. This safety assessment was prepared by Alice Akinsulie, Scientific Writer/Analyst. © Cosmetic Ingredient Review 1620 L Street, NW, Suite 1200 ♢ Washington, DC 20036-4702 ♢ ph 202.331.0651 ♢ fax 202.331.0088 ♢ [email protected] Commitment & Credibility since 1976 Memorandum To: CIR Expert Panel Members and Liaisons From: Alice Akinsulie, Scientific Analyst/Writer Date: November 9, 2018 Subject: Draft Safety Assessment of Benzyl Salicylate as Used in Cosmetics Enclosed is the Draft Report of the Safety Assessment of Benzyl Salicylate as Used in Cosmetics. (It is identified as bensal122018rep in the pdf document.) On October 9, 2018, CIR issued the Scientific Literature Review (SLR) for this ingredient. According to the Dictionary, Benzyl Salicylate is reported to function mainly as a fragrance ingredient and light stabilizer. The Personal Care Products Council (Council) provided concentration of use survey data for the light stabilizer function (only) of Benzyl Salicylate. The results indicate that the light stabilizer concentrations of use for Benzyl Salicylate falls in the IFRA Standards for use of Benzyl Salicylate as a fragrance ingredient (identified as bensal122018data). -
Effect of Alkali Carbonate/Bicarbonate on Citral Hydrogenation Over Pd/Carbon Molecular Sieves Catalysts in Aqueous Media
Modern Research in Catalysis, 2016, 5, 1-10 Published Online January 2016 in SciRes. http://www.scirp.org/journal/mrc http://dx.doi.org/10.4236/mrc.2016.51001 Effect of Alkali Carbonate/Bicarbonate on Citral Hydrogenation over Pd/Carbon Molecular Sieves Catalysts in Aqueous Media Racharla Krishna, Chowdam Ramakrishna, Keshav Soni, Thakkallapalli Gopi, Gujarathi Swetha, Bijendra Saini, S. Chandra Shekar* Defense R & D Establishment, Gwalior, India Received 18 November 2015; accepted 5 January 2016; published 8 January 2016 Copyright © 2016 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract The efficient citral hydrogenation was achieved in aqueous media using Pd/CMS and alkali addi- tives like K2CO3. The alkali concentrations, reaction temperature and the Pd metal content were optimized to enhance the citral hydrogenation under aqueous media. In the absence of alkali, ci- tral hydrogenation was low and addition of alkali promoted to ~92% hydrogenation without re- duction in the selectivity to citronellal. The alkali addition appears to be altered the palladium sites. The pore size distribution reveals that the pore size of these catalysts is in the range of 0.96 to 0.7 nm. The palladium active sites are also quite uniform based on the TPR data. The catalytic parameters are correlated well with the activity data. *Corresponding author. How to cite this paper: Krishna, R., Ramakrishna, C., Soni, K., Gopi, T., Swetha, G., Saini, B. and Shekar, S.C. (2016) Effect of Alkali Carbonate/Bicarbonate on Citral Hydrogenation over Pd/Carbon Molecular Sieves Catalysts in Aqueous Media. -
International Journal of Advanced Scientific and Technical Research
International journal of advanced scientific and technical research Issue 5 volume 1, January-February 2015 Available online on http://www.rspublication.com/ijst/index.html ISSN 2249-9954 Degradation Studies on Bronopol in Oral Hygiene Formulations Jampala Balaji1*, N.K.Sarthchandra Prakash2, 3 Krishan Manaral R&D Department, The Himalaya Drug Company, Makali, Bangalore, India-562162. ABSTRACT This study investigated the decomposition of Bronopol and its degradation products how they produce Nitrosamines in oral hygiene products. Based on this study Bronopol was degradable in oral hygiene products which are containing aqueous medium, higher pH values (4 to10) and which are presented in higher temperatures and then gives formaldehyde, and nitro compounds. These nitro compounds are acting as a nitrosating agent and react with secondary amines then give Nitrosamines in the products. The degradation study was done by using determination of mass by LCMS and determination of formaldehyde content by Head-Space GC. These studies strongly demonstrate the Bronopol was degradable in aqueous medium and give formaldehyde and nitro compounds. Bronopol was not acting itself as a nitrosating agent and its degradation products act as a nitrosating agent. The products which are containing the secondary amines and the nitrosating agent then the Nitrosamines are formed in that product. Keywords: Bronopol, Degradation, Nitrosamines, Formaldehyde, Oral hygiene products. INTRODUCTION Bronopol is an organic compound also called as a 2-bromo-2-nitropropane-1, 3- diol (Molecular formula: C(Br)(NO2)(CH2OH)2). In cosmetics Bronopol is used as an antibacterial preservative to prevent spoilage due to microbial contamination [1]. Bronopol structure was shown in fig1. -
RAFT Memorabilia : Living Radical Polymerization in Homogeneous and Heterogeneous Media / by Hans De Brouwer
RAFT memorabilia ❉ living ❉ radical polymerization in homogeneous and heterogeneous media Hans de Brouwer CIP-DATA LIBRARY TECHNISCHE UNIVERSITEIT EINDHOVEN Brouwer, Hans de RAFT memorabilia : living radical polymerization in homogeneous and heterogeneous media / by Hans de Brouwer. - Eindhoven : Technische Universiteit Eindhoven, 2001. - Proefschrift. - ISBN 90-386-2802-1 NUGI 813 Trefwoorden: polymerisatie ; radikaalreacties / emulsiepolymerisatie / reactiekinetiek / ketenoverdracht ; RAFT Subject headings: polymerization ; radical reactions / emulsion polymerisation / reaction kinetics / chain transfer ; RAFT © 2001, Hans de Brouwer Druk: Universiteitsdrukkerij, Technische Universiteit Eindhoven Omslagontwerp: Hans de Brouwer RAFT memorabilia living radical polymerization in homogeneous and heterogeneous media PROEFSCHRIFT ter verkrijging van de graad van doctor aan de Technische Universiteit Eindhoven, op gezag van de Rector Magnificus, prof.dr. M. Rem, voor een commissie aangewezen door het College voor Promoties in het openbaar te verdedigen op woensdag 30 mei 2001 om 16.00 uur door Johannes A. M. de Brouwer geboren te Goirle Dit proefschrift is goedgekeurd door de promotoren: prof.dr.ir. A. L. German en prof.dr. J. F. Schork Copromotor: dr. M. J. Monteiro Het werk in dit proefschrift is financieel ondersteund door de Stichting Emulsiepolymerisatie (SEP) / The work in this thesis was financially supported by the Foundation Emulsion polymerization (SEP) look around, wonder why we can live a life that's never satisfied lonely hearts, troubled minds looking for a way that we can never find many roads are ahead of us with choices to be made but life's just one of the games we play there is no special way from Winter in July on the album Unknown Territory by Bomb the Bass © 1991, Rhythm King Records table of contents Table of Contents Chapter 1. -
INDEX to PESTICIDE TYPES and FAMILIES and PART 180 TOLERANCE INFORMATION of PESTICIDE CHEMICALS in FOOD and FEED COMMODITIES
US Environmental Protection Agency Office of Pesticide Programs INDEX to PESTICIDE TYPES and FAMILIES and PART 180 TOLERANCE INFORMATION of PESTICIDE CHEMICALS in FOOD and FEED COMMODITIES Note: Pesticide tolerance information is updated in the Code of Federal Regulations on a weekly basis. EPA plans to update these indexes biannually. These indexes are current as of the date indicated in the pdf file. For the latest information on pesticide tolerances, please check the electronic Code of Federal Regulations (eCFR) at http://www.access.gpo.gov/nara/cfr/waisidx_07/40cfrv23_07.html 1 40 CFR Type Family Common name CAS Number PC code 180.163 Acaricide bridged diphenyl Dicofol (1,1-Bis(chlorophenyl)-2,2,2-trichloroethanol) 115-32-2 10501 180.198 Acaricide phosphonate Trichlorfon 52-68-6 57901 180.259 Acaricide sulfite ester Propargite 2312-35-8 97601 180.446 Acaricide tetrazine Clofentezine 74115-24-5 125501 180.448 Acaricide thiazolidine Hexythiazox 78587-05-0 128849 180.517 Acaricide phenylpyrazole Fipronil 120068-37-3 129121 180.566 Acaricide pyrazole Fenpyroximate 134098-61-6 129131 180.572 Acaricide carbazate Bifenazate 149877-41-8 586 180.593 Acaricide unclassified Etoxazole 153233-91-1 107091 180.599 Acaricide unclassified Acequinocyl 57960-19-7 6329 180.341 Acaricide, fungicide dinitrophenol Dinocap (2, 4-Dinitro-6-octylphenyl crotonate and 2,6-dinitro-4- 39300-45-3 36001 octylphenyl crotonate} 180.111 Acaricide, insecticide organophosphorus Malathion 121-75-5 57701 180.182 Acaricide, insecticide cyclodiene Endosulfan 115-29-7 79401 -
Western Flower Thrips Management on Greenhouse-Grown Crops
Western Flower Thrips Management on Greenhouse-Grown Crops Greenhouse producers worldwide are familiar with the Eggs hatch in two to four days. Nymphs feed on both western flower thrips, Frankliniella occidentalis (Pergande), leaves and flowers. The first nymphal stage lasts one to one of the most destructive insect pests of greenhouse- two days; the second nymphal stage, two to four days. grown crops. Western flower thrips, the primary thrips Second instar nymphs are typically more active and tend species encountered by greenhouse producers, is extremely to feed more than first instar nymphs. The second instar polyphagous, feeding on a wide-variety of horticultural nymph eventually migrates to the plant base and enters crops grown in both commercial and research greenhouses. the growing medium to pupate. Western flower thrips also This insect pest has been included in greenhouse pest pupate in leaf debris, on the plant, and in the open flowers control brochures since 1949. It was not considered a of certain types of plants including chrysanthemum. There major insect pest of greenhouse-grown crops until the are actually two “pupal” stages: a prepupa (or propupa) and 1980s. This publication addresses biology and damage; pupa. Both stages commonly occur in growing medium or scouting; and cultural, physical, insecticidal, and biological soil underneath benches. management. The issues discussed should provide insight Growing medium or soil type and pH and pupation depth on the importance of dealing with western flower thrips may influence pupal survival. Pupation depth depends on holistically instead of solely relying on insecticides. growing medium or soil type. Pupae stages do not feed Biology and Feeding Damage and are tolerant or immune to most insecticides commonly Knowledge of biology and damage is important in applied to manage western flower thrips nymphs and understanding the challenges associated with developing adults. -
Redalyc.Degradation of Citronellol, Citronellal and Citronellyl Acetate By
Electronic Journal of Biotechnology E-ISSN: 0717-3458 [email protected] Pontificia Universidad Católica de Valparaíso Chile Tozoni, Daniela; Zacaria, Jucimar; Vanderlinde, Regina; Longaray Delamare, Ana Paula; Echeverrigaray, Sergio Degradation of citronellol, citronellal and citronellyl acetate by Pseudomonas mendocina IBPse 105 Electronic Journal of Biotechnology, vol. 13, núm. 2, marzo, 2010, pp. 1-7 Pontificia Universidad Católica de Valparaíso Valparaíso, Chile Available in: http://www.redalyc.org/articulo.oa?id=173313806002 How to cite Complete issue Scientific Information System More information about this article Network of Scientific Journals from Latin America, the Caribbean, Spain and Portugal Journal's homepage in redalyc.org Non-profit academic project, developed under the open access initiative Electronic Journal of Biotechnology ISSN: 0717-3458 Vol.13 No.2, Issue of March 15, 2010 © 2010 by Pontificia Universidad Católica de Valparaíso -- Chile Received April 24, 2009 / Accepted November 6, 2009 DOI: 10.2225/vol13-issue2-fulltext-8 RESEARCH ARTICLE Degradation of citronellol, citronellal and citronellyl acetate by Pseudomonas mendocina IBPse 105 Daniela Tozoni Instituto de Biotecnologia Universidade de Caxias do Sul R. Francisco G. Vargas 1130 Caxias do Sul, RS, Brazil Jucimar Zacaria Instituto de Biotecnologia Universidade de Caxias do Sul R. Francisco G. Vargas 1130 Caxias do Sul, RS, Brazil Regina Vanderlinde Instituto de Biotecnologia Universidade de Caxias do Sul R. Francisco G. Vargas 1130 Caxias do Sul, RS, Brazil Ana Paula Longaray Delamare Universidade de Caxias do Sul R. Francisco G. Vargas 1130 Caxias do Sul, RS, Brazil Sergio Echeverrigaray* Universidade de Caxias do Sul R. Francisco G. Vargas 1130 Caxias do Sul, RS, Brazil E-mail: [email protected] Financial support: COREDES/FAPERGS, and D. -
1,2-DICHLOROETHANE 1. Exposure Data
1,2-DICHLOROETHANE Data were last reviewed in IARC (1979) and the compound was classified in IARC Monographs Supplement 7 (1987a). 1. Exposure Data 1.1 Chemical and physical data 1.1.1 Nomenclature Chem. Abstr. Serv. Reg. No.: 107-06-2 Chem. Abstr. Name: 1,2-Dichloroethane IUPAC Systematic Name: 1,2-Dichloroethane Synonym: Ethylene dichloride 1.1.2 Structural and molecular formulae and relative molecular mass Cl CH2 CH2 Cl C2H4Cl2 Relative molecular mass: 98.96 1.1.3 Chemical and physical properties of the pure substance (a) Description: Colourless liquid with a pleasant odour (Budavari, 1996) (b) Boiling-point: 83.5°C (Lide, 1995) (c) Melting-point: –35.5°C (Lide, 1995) (d) Solubility: Slightly soluble in water; miscible with ethanol, chloroform and diethyl ether (Lide, 1995; Budavari, 1996) (e) Vapour pressure: 8 kPa at 20°C (Verschueren, 1996) (f) Flash-point: 18°C, open cup (Budavari, 1996) (g) Conversion factor: mg/m3 = 4.0 × ppm 1.2 Production and use World production capacities in 1988 for 1,2-dichloroethane have been reported as follows (thousand tonnes): North America, 9445; western Europe, 9830; Japan, 3068; and other, 8351 (Snedecor, 1993). Production in the United States has been reported as follows (thousand tonnes): 1983, 5200; 1990, 6300; 1991, 6200; 1992, 6900; 1993, 8100 (United States National Library of Medicine, 1997). The total annual production in Canada in 1990 was estimated to be 922 thousand tonnes; more than 1000 thousand tonnes were produced in the United Kingdom in 1991 (WHO, 1995). –501– 502 IARC MONOGRAPHS VOLUME 71 1,2-Dichloroethane is used primarily in the production of vinyl chloride; 99% of total demand in Canada, 90% in Japan and 88% of total production in the United States are used for this purpose.