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Multidisciplinary Chemistry Journals Best of Multidisciplinary Chemistry Journals FREE access to top articles Inspiring Chemistry A journal of www.angewandte.org FREE Sample Copy Chair of the Editor-in-Chief: Editorial Board: Peter Gölitz Alois Fürstner (Mülheim) Highlights: Editorial Board: • Free App available: bit.ly/CHEMAPPS Annette G. Beck-Sickinger Andreas Kreimeyer - “The Angew. Chem. App is fantastic. (Leipzig) (Ludwigshafen) Very intuitive and informative. It is a Matthias Beller (Rostock) Christof M. Niemeyer very nice way to quickly find content Hans-Joachim Böhm (Basel) (Dortmund) relevant to one’s work” Stefan Buchholz (Essen) Wolfgang Parak (Marburg) (Chad A. Mirkin) Thomas Carell (Munich) Ferdi Schüth (Mülheim) - “I use the Angewandte app all the Claus Feldmann (Karlsruhe) Petra Schwille (Dresden) time. I love it! It’s great to be able Roland Fischer (Bochum) Martin Suhm (Göttingen) to download entire issues for offline Thomas Geelhaar (Darmstadt) Brigitte Voit (Dresden) reading.” (Phil S. Baran) Stefan Grimme (Bonn) Herbert Waldmann (Dortmund) • Follow us on Twitter and Facebook Hansjörg Grützmacher (Zurich) Hanno Wild (Wuppertal) International Advisory Board: Comprising 44 world-renowned scientists, including Nobel Laureates Roald Hoffmann, Jean-Marie Lehn, Ryoji Noyori, and Ahmed Zewail. “Angewandte Chemie combines a unique portfolio of publication types in a highly attractive format. Reading the journal daily online ensures that I keep up to date with the progress in my own fields of research and all other areas of chemistry.” (François Diederich) 2 Mixed Transition Metal Oxides: Design, Synthesis, and Energy Related Applications Changzhou Yuan, Hao Bin Wu, Yi Xie*, Xiong Wen (David) Lou* Full of energy: Recent advances in the rational design and synthesis of mixed transition-metal oxides (MTMOs, designated as AxB3−xO4) with controllable compositions and structures and their applications in various electrochemical energy storage/ conversion technologies are summarized and discussed (see picture). Future trends and prospects for their further Angew. Chem. Int. Ed. DOI: 10.1002/anie.201303971 development are also discussed. Chemistry with Graphene and Graphene Oxide – Challenges for Synthetic Chemists Siegfried Eigler*, Andreas Hirsch* The well-controlled synthesis of new graphene and graphene oxide derivatives as well as determination of the atomic structure are key challenges for synthetic chemists. Structure–property relationships must be exploited to use the full potential of graphene derivatives in upcoming applications. This Review focuses on Angew. Chem. Int. Ed. concepts in the chemistry of graphene and graphene oxide with the DOI: 10.1002/anie.201402780 aim of encouraging chemists to enhance the field of research. Sulfur(VI) Fluoride Exchange (SuFEx): Another Good Reaction for Click Chemistry Jiajia Dong, Larissa Krasnova, M. G. Finn, K. Barry Sharpless* Old chemistry in new glory: Sulfonyl fluoride exchange (SuFEx) forges rugged inorganic links between carbon centers. Like most click reactions, it is an old process now improved to allow the underappreciated sulfate connection to be made for a variety of Angew. Chem. Int. Ed. purposes. The various exchange events uniquely enabled by the DOI: 10.1002/anie.201309399 use of fluoride are highlighted here in orange. Engineered Nanoparticles for Drug Delivery in Cancer Therapy Tianmeng Sun, Yu Shrike Zhang, Bo Pang, Dong Choon Hyun, Miaoxin Yang, Younan Xia* On the way to nanomedicine: Considerable advances in the development of nanoparticles for cancer therapy have been made in recent years. Nanoparticle-based drug-delivery systems offer advantages with regard to multidrug resistance, systemic delivery, and clearance, and enable for example specific tumor targeting Angew. Chem. Int. Ed. and controlled release of therapeutic agents.use of fluoride are DOI: 10.1002/anie.201403036 highlighted here in orange. 3 ChemPubSoc Europe’s A journal of flagship journal www.chemeurj.org FREE Sample Copy Chair of the Editor-in-Chief: Editorial Board: Neville Compton Jan-Erling Bäckvall Stockholms Universitet Highlights: Editorial Board: • Celebrating 20 years of publication. Comprising 59 world-renowned scientists. Discover for free at Honorary Members: http://bit.ly/CEJ20: Vincenzo Balzani (Università degli Studi di Bologna), Italy • Top 20 all time most cited papers Gerhard Ertl (Fritz-Haber-Institut, Berlin), Germany • Top 20 most cited Reviews and Jean-Marie Lehn (Université de Strasbourg/Collège de Minireviews France, Paris), France • Top 20 most cited Concepts Armin de Meijere (Georg-August-Universitt Göttingen), Germany • Top 20 most cited Communications Kyriacos C. Nicolaou (Rice University, Houston), USA • Top 20 most cited Full Papers David Reinhoudt (University of Twente), The Netherlands • Top 20 most prolific authors J. Fraser Stoddart (Northwestern University, Evanston), USA • Free App available: bit.ly/CHEMAPPS Barry Trost (Stanford University, Stanford, CA), USA • Supported by ACES • Follow us on Twitter and Facebook • Cover Profiles: Find out more about the chemistry and the research groups “Chemistry – A European Journal has always been the gold highlighted on the front cover standard of chemistry for me.” (Martin Pumera, Editorial Board Member) 4 Masked Rhodamine Dyes of Five Principal Colors Revealed by Photolysis of a 2 Diazo 1 Indanone Caging Group: Synthesis, Photophysics, and Light Microscopy Applications Vladimir N. Belov*, Gyuzel Yu. Mitronova, Mariano L. Bossi*, Vadim P. Boyarskiy, Elke Hebisch, Claudia Geisler, Kirill Kolmakov, Christian A. Wurm, Katrin I. Willig, Stefan W. Hell* Masked fluorophores: New photoactivatable rhodamine dyes (see scheme) have been designed, decorated with a reactive group, conjugated with proteins, and used as labels in immunofluorescence and optical microscopy. These “hidden” markers can be readily and irreversibly “uncaged” with λ=375–420 nm or intense red light.conversion technologies are summarized and discussed (see picture). Future trends and prospects for their further Chem. Eur. J. DOI: 10.1002/chem.201403316 development are also discussed. Palladium Catalysed Direct Cross Coupling of Organolithium Reagents with Aryl and Vinyl Triflates Carlos Vila, Valentín Hornillos, Massimo Giannerini, Martín Fañanás-Mastral, Ben L. Feringa* Cut out the middle man! A palladium-catalysed direct cross- coupling of organolithium reagents with aryl and vinyl triflates is presented. The reaction proceeds at 50 or 70 °C with short reaction Chem. Eur. J. times, and the corresponding products are obtained with moderate DOI:10.1002/chem.201404398 to high yields (see scheme). Metal Nanoparticles and Supramolecular Macrocycles: A Tale of Synergy Verónica Montes-García, Jorge Pérez-Juste*, Isabel Pastoriza-Santos, Luis M. Liz-Marzán* Nanoparticles and macrocycles: Recent literature regarding the combination of supramolecular macrocycles and metal nanoparticles is reviewed, with particular emphasis on the synthesis, surface modification and assembly, as well as Chem. Eur. J. the potential applications of the obtained nanocomposites DOI: 10.1002/chem.201403107 (SERS = surface-enhanced Raman spectroscopy). Transition-Metal-Free Catalytic Reduction of Carbon Dioxide Prof. Frédéric-Georges Fontaine, Marc-André Courtemanche and Marc-André Légaré Less is more: Metal-free systems, including frustrated Lewis pairs (FLPs), have been shown to bind CO2. By reducing the Lewis acidity and basicity of the ambiphilic system, it is possible to generate active catalysts for the deoxygenative hydroboration of carbon dioxide to Chem. Eur. J. methanol derivatives with conversion rates comparable to those of DOI: 10.1002/chem.201304376 transition-metal-based catalysts (see scheme). 5 Rooted in Asia, A journal of read all over the world www.chemasianj.org FREE Sample Copy Editor-in-Chief: Chair of the Editorial Board: Theresa Kueckmann Ryoji Noyori, Nagoya University, Japan, and RIKEN, Saitama, Japan Editorial Board: Ayyappanpillai Ajayaghosh (CSIR National Institute for Highlights: Interdisciplinary Science and Technology, Thiruvananthapuram) • Next day publication of accepted Jaephil Cho (Ulsan National Institute of Science and Technology) articles Insung S. Choi (Korea Advanced Institute of Science and Technology, Daejeon) • Celebrating 10 years of publication. Xinliang Feng (Technical University, Dresden) Discover at http://bit.ly/ChemAsia10: Makoto Fujita (University of Tokyo) 10 Most cited articles, Top authors, Top Itaru Hamachi (Kyoto University) referees, Special anniversary issues, Michael H. Huang (National Tsing Hua University, Hsinchu) Upcoming celebrations, The hottest Susumu Kitagawa (Kyoto University) topics covered Shū Kobayashi (University of Tokyo) • International readers and authors Aiwen Lei (Wuhan University) • Co-owned by the 13 chemical societies Xiaogang Liu (National University of Singapore) of ACES and supported by ChemPubSoc Jian Pei (Peking University, Beijing) Europe and FACS Thalappil Pradeep (Indian Institute of Technology Madras, Chennai) • Articles featured on Zhigang Shuai (Tsinghua University, Beijing) www.facebook.com/chemasianj Kazuyuki Tatsumi (Nagoya University) and twitter @chemasianj Yoshio Umezawa (Musashino University, Tokyo) Henry N. C. Wong (Chinese University of Hong Kong) • Free App available: bit.ly/CHEMAPPS Zhenzhong Yang (Institute of Chemistry, Chinese Academy of Sciences, Beijing) International Advisory Board: Comprising 72 world-renowned scientists, including Nobel Laureates Robert H. Grubbs, Jean-Marie Lehn, Richard R. Schrock, and
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  • Shelf-Stable Electrophilic Trifluoromethylating Reagents: a Brief Historical Perspective
    Shelf-stable electrophilic trifluoromethylating reagents: A brief historical perspective Norio Shibata*1, Andrej Matsnev1 and Dominique Cahard*2 Review Open Access Address: Beilstein J. Org. Chem. 2010, 6, No. 65. doi:10.3762/bjoc.6.65 1Department of Frontier Materials, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso, Showa-ku, Nagoya Received: 15 March 2010 466-8555, Japan and 2UMR 6014 CNRS – C.O.B.R.A. Université et Accepted: 21 May 2010 INSA de Rouen, 1 rue Tesnière, 76130 Mont Saint Aignan, France Published: 16 June 2010 Email: Guest Editor: D. O'Hagan Norio Shibata* - [email protected]; Dominique Cahard* - [email protected] © 2010 Shibata et al; licensee Beilstein-Institut. License and terms: see end of document. * Corresponding author Keywords: asymmetric synthesis; electrophilic; fluorine; reagent; trifluoromethylation Abstract Since the discovery by Yagupolskii and co-workers that S-trifluoromethyl diarylsulfonium salts are effective for the trifluoro- methylation of thiophenolates, the design and synthesis of electrophilic trifluoromethylating reagents have been extensively researched in both academia and industry, due to the significant unique features that trifluoromethylated compounds have in phar- maceuticals, agricultural chemicals, and functional materials. Several effective reagents have been developed by the groups of Yagupolskii, Umemoto, Shreeve, Adachi, Magnier, Togni and Shibata. Due to the high stability and reactivity of these reagents, a series of Umemoto reagents, Togni reagent and Shibata reagent are now commercially available. In this review, we wish to briefly provide a historical perspective of the development of so-called “shelf-stable electrophilic trifluoromethylating reagents”, although this field is in constant development. Review The chemistry of fluoro-organic compounds is one of the areas [3].
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  • Cu-Catalyzed Trifluoromethylation of Aryl Iodides with Trifluoromethylzinc Reagent Prepared in Situ from Trifluoromethyl Iodide
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  • Development of Copper-Catalyzed Electrophilic Trifluoromethylation And
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  • Fluoroform Synthesis and Uses Thereof in the Preparation of Trifluoromethylated Compounds
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