View metadata, citation and similar papers at core.ac.uk brought to you by CORE provided by GEO-LEOe-docs BMC Biology BioMed Central Research article Open Access A rapidly evolving secretome builds and patterns a sea shell Daniel J Jackson1,2, Carmel McDougall1,4, Kathryn Green1, Fiona Simpson3, Gert Wörheide2 and Bernard M Degnan*1 Address: 1School of Integrative Biology, University of Queensland, Brisbane Qld 4072, Australia, 2Department of Geobiology, Geoscience Centre, University of Göttingen, Goldschmidtstr.3, 37077 Göttingen, Germany, 3Institute of Molecular Biosciences, University of Queensland, Brisbane Qld 4072, Australia and 4Department of Zoology, University of Oxford, Tinbergen Bldg., South Parks Road, Oxford OX1 3PS, UK Email: Daniel J Jackson -
[email protected]; Carmel McDougall -
[email protected]; Kathryn Green -
[email protected]; Fiona Simpson -
[email protected]; Gert Wörheide -
[email protected] goettingen.de; Bernard M Degnan* -
[email protected] * Corresponding author Published: 22 November 2006 Received: 27 July 2006 Accepted: 22 November 2006 BMC Biology 2006, 4:40 doi:10.1186/1741-7007-4-40 This article is available from: http://www.biomedcentral.com/1741-7007/4/40 © 2006 Jackson et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Instructions to fabricate mineralized structures with distinct nanoscale architectures, such as seashells and coral and vertebrate skeletons, are encoded in the genomes of a wide variety of animals.