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Oogenesis [PDF] Oogenesis Dr Navneet Kumar Professor (Anatomy) K.G.M.U Dr NavneetKumar Professor Anatomy KGMU Lko Oogenesis • Development of ovum (oogenesis) • Maturation of follicle • Fate of ovum and follicle Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Oogenesis • Site – ovary • Duration – 7th week of embryo –primordial germ cells • -3rd month of fetus –oogonium • - two million primary oocyte • -7th month of fetus primary oocyte +primary follicle • - at birth primary oocyte with prophase of • 1st meiotic division • - 40 thousand primary oocyte in adult ovary • - 500 primary oocyte attain maturity • - oogenesis completed after fertilization Dr Navneet Kumar Dr NavneetKumar Professor Professor (Anatomy) Anatomy KGMU Lko K.G.M.U Development of ovum Oogonium(44XX) -In fetal ovary Primary oocyte (44XX) arrest till puberty in prophase of 1st phase meiotic division Secondary oocyte(22X)+Polar body(22X) 1st phase meiotic division completed at ovulation &enter in 2nd phase Ovum(22X)+polarbody(22X) After fertilization Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Dr Navneet Kumar Dr ProfessorNavneetKumar (Anatomy) Professor K.G.M.UAnatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Maturation of follicle Dr NavneetKumar Professor Anatomy KGMU Lko Maturation of follicle Primordial follicle -Follicular cells Primary follicle -Zona pallucida -Granulosa cells Secondary follicle Antrum developed Ovarian /Graafian follicle - Theca interna &externa -Membrana granulosa -Antrial cavity -Discus proligerus -Cumulus oophoricus Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Ovulation Dr NavneetKumar Professor Anatomy KGMU Lko Structure of ovum • Secondary oocyte • Vitellus • Nucleus -phase of 2ed meiotic division • Vitelline membrane • Previtelline space 1st polor body • Zona pellucida • Corona radiata Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Fate of ovarian follicle Formation of Corpus luteum • After ovulation ovarian follicle Ruptured and folded Corpus luteum • Follicular cells/granulosa cells -Cells of membrana granulosa -lutien pigment • Luteal cells • Theacal cells Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Corpus luteum • Corpus luteum of pregnancy • Corpus luteum of menstruation Dr NavneetKumar Professor Anatomy KGMU Lko Fate of follicle Dr NavneetKumar Professor Anatomy KGMU Lko Fate of follicle • Corpus luteum -Corpus albicans • Corpora atretica -interstitial gland Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .1. Oogenesis starts (a) at puberty (b) after birth (c) at early fetal life (d) during ovulation Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .2. Secondary oocyte are formed (a) after fertilization (b) at birth (c) at early fetal life (d) after ovulation Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .3. Unovulated ovarian follicle coverts as (a) corpus luteum (b) interstitial gland (c) luteal gland (d) tertiary follicle Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .4. After fertilization , corpus luteum may persist up to (a) 14 days (b) 28 days (c) 3 months (d) 9 months Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .5. Zona pallucida is present around (a) ovum (b) theca interna (c) membrama granulosa (d) corpus luteum Dr NavneetKumar Professor Anatomy KGMU Lko .
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