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Dr Navneet Kumar Professor () K.G.M.U

Dr NavneetKumar Professor Anatomy KGMU Lko Oogenesis

• Development of ovum (oogenesis) • Maturation of follicle • Fate of ovum and follicle

Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Oogenesis

• Site – • Duration – 7th week of –primordial germ cells • -3rd month of fetus – • - two million primary • -7th month of fetus primary oocyte +primary follicle • - at primary oocyte with of • 1st meiotic division • - 40 thousand primary oocyte in adult ovary • - 500 primary oocyte attain maturity • - oogenesis completed after fertilization

Dr Navneet Kumar Dr NavneetKumar Professor Professor (Anatomy) Anatomy KGMU Lko K.G.M.U Development of ovum Oogonium(44XX) -In fetal ovary Primary oocyte (44XX) arrest till in prophase of 1st phase meiotic division Secondary oocyte(22X)+(22X) 1st phase meiotic division completed at &enter in 2nd phase Ovum(22X)+polarbody(22X) After fertilization

Dr NavneetKumar Professor Anatomy KGMU Lko

Dr NavneetKumar Professor Anatomy KGMU Lko

Dr Navneet Kumar Dr ProfessorNavneetKumar (Anatomy) Professor K.G.M.UAnatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Maturation of follicle

Dr NavneetKumar Professor Anatomy KGMU Lko Maturation of follicle

Primordial follicle -Follicular cells Primary follicle -Zona pallucida -Granulosa cells Secondary follicle Antrum developed Ovarian /Graafian follicle - interna &externa - -Antrial cavity -Discus proligerus -Cumulus oophoricus

Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko

Dr NavneetKumar Professor Anatomy KGMU Lko Ovulation

Dr NavneetKumar Professor Anatomy KGMU Lko Structure of ovum

• Secondary oocyte • Vitellus • Nucleus -phase of 2ed meiotic division • • Previtelline space 1st polor body • • Corona radiata

Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Fate of

Formation of • After ovulation ovarian follicle Ruptured and folded Corpus luteum • Follicular cells/granulosa cells -Cells of membrana granulosa -lutien pigment • Luteal cells • Theacal cells

Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko Corpus luteum

• Corpus luteum of

• Corpus luteum of

Dr NavneetKumar Professor Anatomy KGMU Lko

Fate of follicle

Dr NavneetKumar Professor Anatomy KGMU Lko Fate of follicle

• Corpus luteum - • Corpora atretica -interstitial gland

Dr NavneetKumar Professor Anatomy KGMU Lko

Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko

Dr NavneetKumar Professor Anatomy KGMU Lko Dr NavneetKumar Professor Anatomy KGMU Lko

Dr NavneetKumar Professor Anatomy KGMU Lko

Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .1.

Oogenesis starts (a) at puberty (b) after birth (c) at early fetal life (d) during ovulation

Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .2.

Secondary oocyte are formed (a) after fertilization (b) at birth (c) at early fetal life (d) after ovulation

Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .3.

Unovulated ovarian follicle coverts as (a) corpus luteum (b) interstitial gland (c) luteal gland (d) tertiary follicle

Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .4.

After fertilization , corpus luteum may persist up to (a) 14 days (b) 28 days (c) 3 months (d) 9 months

Dr NavneetKumar Professor Anatomy KGMU Lko M.C.Q .5.

Zona pallucida is present around (a) ovum (b) (c) membrama granulosa (d) corpus luteum

Dr NavneetKumar Professor Anatomy KGMU Lko