CHMP5 polyclonal antibody

Catalog # : PAB6771 規格 : [ 100 ug ] List All

Specification Application Image

Product Goat polyclonal antibody raised against synthetic peptide of CHMP5. Western Blot (Cell lysate) Description:

Immunogen: A synthetic peptide corresponding to human CHMP5.

Sequence: C-NKDGVLVDEFGLPQ enlarge Host: Goat ELISA Theoretical MW 24.5 (kDa):

Reactivity: Human

Form: Liquid

Purification: Antigen affinity purification

Concentration: 0.5 mg/mL

Quality Control Antibody Reactive Against Synthetic Peptide. Testing:

Recommend ELISA (1:8000) Usage: Western Blot (1-3 ug/mL) The optimal working dilution should be determined by the end user.

Storage Buffer: In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)

Storage Store at -20°C. Instruction: Aliquot to avoid repeated freezing and thawing.

Note: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Datasheet: Download

Publication Reference 1. The role of LIP5 and CHMP5 in multivesicular body formation and HIV-1 budding in mammalian cells. Ward DM, Vaughn MB, Shiflett SL, White PL, Pollock AL, Hill J, Schnegelberger R, Sundquist WI, Kaplan J.J Biol Chem. 2005 Mar 18;280(11):10548-55. Epub 2005 Jan 11.

Applications

Western Blot (Cell lysate)

Page 1 of 2 2017/2/16 CHMP5 polyclonal antibody (Cat # PAB6771) (0.5 ug/mL) staining of K-562 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

ELISA

Gene Information

Entrez GeneID: 51510

Protein NP_057494.2 Accession#:

Gene Name: CHMP5

Gene Alias: C9orf83,CGI-34,HSPC177,PNAS-2,SNF7DC2

Gene chromatin modifying protein 5 Description:

Omim ID: 610900

Gene Ontology: Hyperlink

Gene Summary: CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM

Other OTTHUMP00000021197,SNF7 domain containing 2 Designations:

Gene Pathway Endocytosis

服務條款 | 隱私權政策 | 著作及商標 | 網站地圖 ©2017 亞諾法生技股份有限公司 Abnova Corporation. 版權所有.

Page 2 of 2 2017/2/16