DOCSLIB.ORG

Sequential Culture Media System

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Sequential Culture Media System SEQUENTIAL CULTURE MEDIA SYSTEM Contents Gamete solutions ................................................................................ 7 Fertilization solutions ........................................................................15 Cleavage solutions ............................................................................21 Blastocyst solutions...........................................................................25 Complete list of order numbers ....................................................30 Nurture gametes and embryos with the nutrients they need. Our culture system mimics the delicate and dynamic environment of the female reproductive tract by providing nutrients to meet the shifting metabolic requirements of gametes and embryos. SOLUTIONS GAMETE Gamete collection and preparation might be the most stressful process in IVF, and the environmental disruption that occurs can significantly impair gamete viability. These gamete solutions meet the metabolic requirements of the oocyte and help to maintain oocyte homeostasis so that subsequent steps in IVF can succeed. 7 GAMETE FERTILIZATION CLEAVAGE BLASTOCYST SOLUTIONS SOLUTIONS SOLUTIONS SOLUTIONS 8 SYDNEY IVF GAMETE BUFFER Sydney IVF Gamete Buffer is used to physically wash and CONSTITUENTS store gametes in preparation for the fertilization step in the Calcium lactate L-proline IVF process. D-glucose L-serine • Designed to be used in atmospheric air conditions, not Gentamicin Magnesium sulphate Glutamine, stabilized Potassium chloride SOLUTIONS GAMETE an enriched CO2 environment Glycine Potassium phosphate • HEPES buffered HEPES Purified water • Designed to prepare oocytes and maintain a stable envi- Human serum albumin (HSA)* Sodium bicarbonate ronment during washing of cumulus-enclosed oocytes. L-alanine Sodium chloride • Designed to prepare sperm for swim-up, density L-asparagine Sodium pyruvate gradient, and diluent procedures L-aspartic acid Taurine L-glutamic acid • Can be used during ICSI SOLUTIONS FERTILIZATION USAGE RELEASE SPECIFICATIONS Sydney IVF Gamete Buffer is designed for gamete washing, pH (in air): 7.3-7.5 swim-up procedures, and use as a diluent in density Osmolality: 285-295 mOsm/kg gradient and sperm-thawing procedures. It can also be used 2-cell MEA: ≥ 80% of control expanded for ICSI when a HEPES-buffered environment is required. to blastocysts at 72 hours After ovum aspiration, Sydney IVF Gamete Buffer is used to Endotoxins: < 0.4 EU/mL wash the cumulus-oocyte complex before it is transferred Shelf life: 20 weeks from date of manufacture into Sydney IVF Fertilization Medium. The nonessential Sterile: Aseptically filtered SOLUTIONS CLEAVAGE amino acids prevent the depletion of the oocyte’s internal HSA assay: 5.00–12.50 mg/mL pool of amino acids. HSSA: ≥ 90% of control at 24 hours Order Reference Volume Number Part Number mL G46320 K-SIGB-20-AA 20 G46318 K-SIGB-50-AA 50 G46317 K-SIGB-100-AA 100 SOLUTIONS BLASTOCYST RELATED PRODUCTS Sydney IVF Follicle Flush Buffer Sydney IVF Spermient® Sydney IVF Sperm Gradient Kit Cook® Flexipet® Pipettes We strongly recommend that you record the patient name and lot number every time you use Cook Medical IVF media in a clinical procedure. *We take standard measures to prevent our medicinal human-blood and plasma products from causing infections. These steps include screening individual donations and plasma pools for specific markers of infection and inactivating and removing viruses during manufacture. Despite these safeguards, a possibility exists that medicinal blood or plasma products will transmit infective agents, including unknown or emerging agents or other pathogens. No reports of proven virus transmission have been linked to albumin that was manufactured by established processes to European Pharmacopoeia specifications. We strongly recommend that you record the patient name and lot number every time you use Cook Medical IVF media in a clinical procedure. 9 SYDNEY IVF SPERM MEDIUM Sydney IVF Sperm Medium is intended for use during in CONSTITUENTS vitro fertilization procedures to process sperm. Calcium lactate Potassium chloride • Used for sperm preparation and storage D-glucose Potassium phosphate Gentamicin Purified water • Recommended for swim-up and sperm washing in SOLUTIONS GAMETE Glutamine, stabilized Sodium bicarbonate 6% CO 2 Glycine Sodium chloride USAGE Human serum albumin (HSA)* Sodium pyruvate Sydney IVF Sperm Medium is designed for use with the Magnesium sulphate Taurine swim-up technique to separate motile populations of sperm. Intrauterine insemination can be performed in this medium, RELEASE SPECIFICATIONS or sperm can be resuspended in Sydney IVF Fertilization pH (in air): 7.5-7.8 Medium prior to the insemination of oocytes in vitro. The Osmolality: 285-295 mOsm/kg SOLUTIONS FERTILIZATION product should be equilibrated in 6% CO2 before use. 2-cell MEA: ≥ 80% of control expanded to blastocysts at 72 hours Order Reference Volume Number Part Number mL Endotoxins: < 0.4 EU/mL G46316 K-SISM-20-AA 20 Shelf life: 20 weeks from date of manufacture G46315 K-SISM-50-AA 50 Sterile: Aseptically filtered G46314 K-SISM-100-AA 100 HSA assay: 5.00–12.50 mg/mL RELATED PRODUCTS SOLUTIONS CLEAVAGE Sydney IVF Gamete Buffer Sydney IVF Sperm Gradient Kit Sydney IVF Fertilization Medium IUI catheters SOLUTIONS BLASTOCYST We strongly recommend that you record the patient name and lot number every time you use Cook Medical IVF media in a clinical procedure. *We take standard measures to prevent our medicinal human-blood and plasma products from causing infections. These steps include screening individual donations and plasma pools for specific markers of infection and inactivating and removing viruses during manufacture. Despite these safeguards, a possibility exists that medicinal blood or plasma products will transmit infective agents, including unknown or emerging agents or other pathogens. No reports of proven virus transmission have been linked to albumin that was manufactured by established processes to European Pharmacopoeia specifications. We strongly recommend that you record the patient name and lot number every time you use Cook Medical IVF media in a clinical procedure. 10 SYDNEY IVF SPERM GRADIENT KIT Sydney IVF Sperm Gradient is intended for use during in CONSTITUENTS vitro fertilization procedures to separate motile sperm from Calcium lactate Potassium phosphate seminal plasma. D-glucose Purified water • Sold as a convenient two-part kit for separating motile Gentamicin Silane-coated silica sperm Glutamine, stabilized particles SOLUTIONS GAMETE Glycine Sodium bicarbonate • Contains silane-coated silica HEPES Sodium chloride • Includes one vial of 40% solution and one vial of 80% Human serum albumin (HSA)* Sodium pyruvate solution Magnesium sulphate Taurine Potassium chloride USAGE Sydney IVF Sperm Gradient was designed for use in sperm RELEASE SPECIFICATIONS preparation via density-gradient separation. The gradients pH (in air): 7.3-7.5 SOLUTIONS FERTILIZATION are prepared by adding 1.5 mL of 40% solution underlaid Osmolality: 285-295 mOsm/kg with 1.5 mL of 80% solution in a conical-bottom test tube. 2-cell MEA: ≥ 80% of control expanded The liquefied semen is then overlaid onto the gradients. The to blastocysts at 72 hours test tube is centrifuged, and the resultant pellet is aspirated Endotoxins: < 0.4 EU/mL and washed in Sydney IVF Gamete Buffer. The final pellet is Shelf life: 20 weeks from date of manufacture resuspended in either Sydney IVF Sperm Medium or Sydney Sterile: Aseptically filtered IVF Fertilization Medium. HSA assay: 5.00–12.50 mg/mL Order Reference Volume Number Part Number mL SOLUTIONS CLEAVAGE G46313 K-SISG-20-AA 20 (x2) G46312 K-SISG-50-AA 50 (x2) RELATED PRODUCTS Sydney IVF Gamete Buffer Sydney IVF Sperm Medium Sydney IVF Fertilization Medium SOLUTIONS BLASTOCYST We strongly recommend that you record the patient name and lot number every time you use Cook Medical IVF media in a clinical procedure. *We take standard measures to prevent our medicinal human-blood and plasma products from causing infections. These steps include screening individual donations and plasma pools for specific markers of infection and inactivating and removing viruses during manufacture. Despite these safeguards, a possibility exists that medicinal blood or plasma products will transmit infective agents, including unknown or emerging agents or other pathogens. No reports of proven virus transmission have been linked to albumin that was manufactured by established processes to European Pharmacopoeia specifications. We strongly recommend that you record the patient name and lot number every time you use Cook Medical IVF media in a clinical procedure. 11 SYDNEY IVF SPERMIENT® Sydney IVF Spermient is intended for use during in vitro CONSTITUENTS fertilization procedures to separate motile sperm from Calcium lactate Potassium chloride seminal plasma. D-glucose Potassium phosphate • Sold at a 100% concentration of silane-coated-silica– Gentamicin Purified water SOLUTIONS GAMETE based stock solution to enable customization of sperm Glutamine, stabilized Silane-coated silica density separation Glycine particles HEPES Sodium bicarbonate • Can be diluted with Sydney IVF Gamete Buffer to any Human serum albumin Sodium chloride required concentration (HSA)** Sodium pyruvate USAGE Magnesium sulphate Taurine Sydney IVF Spermient is a 100% stock solution that should be diluted with Sydney IVF Gamete Buffer to the density RELEASE SPECIFICATIONS SOLUTIONS FERTILIZATION required for use (for example,
Load more

Recommended publications
  • How to Fortify Beverages with Calcium by Dr
    Ingredients How to Fortify Beverages With Calcium by Dr. Gerhard Gerstner Along with current developments of the overall functional foods market, the use of minerals and especially calcium salts is expected to exhibit strong growth rates. In contrary to other functional ingredients, calcium is widely known as being beneficial for human health and there is no need to explain its nutritional ad- vantages to the customer. According to Leatherhead International, future trends include growing consumer concern regarding osteoporosis and bone health, leading to increased sales of calcium salts. The con- observation is seen as being one of tinuous market growth drives mineral the main factors causing osteo- Common calium sources salt suppliers to offer not only one porosis 2 .As a consequence, national for beverage fortification product but rather a range of different authorities all over the world have calcium salts and granulations to be recently reconsidered recommend- Table 1 shows a typical range of able to tune them to industrial cus- ations in order to take remedial calcium fortified beverages which tomers’ applications. This article measures against calcium deficiency have been seen in European and US discusses important nutritional, and accordingly, to reduce the risk of supermarkets recently. Practically technological as well as economical osteoporosis. In this respect, the US every type of beverage such as aspects of calcium in beverages with National Institute of Health (NIH) has mineral water, soy milk, energy drink, a focus on our company’s products increased the amounts of optimal nectar or juice does have a fortified Tricalcium Citrate, Calcium Gluconate daily calcium intake and defined product line already.
    [Show full text]
  • Factors Affecting Precipitation of Calcium Lactate from Fermentation Broths and from Aqueous Solution
    https://doi.org/10.3311/PPch.14043 Creative Commons Attribution b |533 Periodica Polytechnica Chemical Engineering, 63(4), pp. 533–540, 2019 Factors Affecting Precipitation of Calcium Lactate from Fermentation Broths and from Aqueous Solution Aladár Vidra1, Áron Németh1*, András Salgó1 1 Department of Applied Biotechnology and Food Science, Faculty of Chemical Technology and Biotechnology, Budapest University of Technology and Economics, H-1111 Budapest, Budafoki út 6-8, Hungary * Corresponding author, e-mail: [email protected] Received: 19 March 2019, Accepted: 22 May 2019, Published online: 28 June 2019 Abstract Lactic acid is one of the most important organic acids which is being extensively used around the globe in a range of industrial and biotechnological applications. Lactic acid can be produced either by fermentation or by chemical synthesis but the biotechnological fermentation process has several advantages compared to the other one. However fermentation broth contains a number of impurities which must be removed from the broth in order to achieve more pure lactic acid. Efficiency of recovery is crucial to the economy of the whole process as well since the costs of separation and recovery are responsible for more than half of the entire cost of production. In the traditional procedure, the heated and filtered fermentation broth is concentrated to allow crystallization or precipitation of calcium lactate, followed by addition of sulphuric acid to remove the calcium in form of calcium sulphate. The disadvantage of this procedure is the relatively high solubility of calcium lactate which causes product loss in the crystallization step. Therefore we investigated the effects of four operating parameters of the crystallization/precipitation process from two different fermentation broths and from an aqueous solution.
    [Show full text]
  • No. 747 for Calcium Lactate in Potato and Vegetable Snacks and Sweetened Crackers
    GRAS Notice (GRN) No. 747 https://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/NoticeInventory/default.htm Exponent 11 50 Connecticut Ave., NW EXponenr Suite 11 00 Washington, DC 20036 telephone 202-772-4900 facsim ile 202-772-4979 www.exponent.com November 14, 2017 Office ofFood Additive Safety (HFS-200) Center for Food Safety and Applied Nutrition Food and Drug Administration 500 l Campus Drive College Park, MD 20740 Subject: GRAS Notification for the Use of Calcium Lactate in Potato and Vegetable Snacks and Sweetened Crackers Project No. 1607280.000 Dear Sir/Madam: In accordance with 2 1 CFR part 170, subpart E, PepsiCo, hereby provides a notice of a claim that the food ingredient described in the enclosed notification document is excluded from the premarket approval requirement ofthe Federal Food, Drug, and Cosmetic Act because the notifier has concluded such use to be generally recognized as safe (GRAS), based on scientific procedures. One paper copy of the notification is provided as required; we also have provided a copy ofthe notification on the enclosed CD-ROM. Ifyou have any questions or require additional information, please do not hesitate to contact me at 202-772-4915, or [email protected]. Sincerely, (b) (6) Nga Tran, DrPH, MPH Principal Scientist ~~©~U~~~ 1607280.000- 04 16 NOV 16 20'7 000001 OFFICE OF FOOD A001TlVE SAFEi'Y ( GRAS Conclusion for the Use of Calcium Lactate in Potato and Vegetable Snacks and Sweetened Crackers SUBMITTED BY: PepsiCo, Inc 700 Anderson Hill Road Purchase, NY 10577 SUBMITTED TO: U.S. Food and Drug Administration Center for Food Safety and Applied Nutrition Office of Food Additive Safety HFS-200 5100 Paint Branch Parkway College Park, MD 20740-3835 CONTACT FOR TECHNICAL OR OTHER INFORMATION: Nga Tran Principal Scientist Exponent, Inc.
    [Show full text]
  • GHS Calcium Lactate Gluconate MSDS.Pdf
    Safety Data Sheet (Calcium Lactate Gluconate) DATE PREPARED: 7/9/2015 Section 1. Product and Company Identification Product Name Calcium Lactate Gluconate CAS Number 11116-97-5 Parchem - fine & specialty chemicals EMERGENCY RESPONSE NUMBER 415 Huguenot Street CHEMTEL New Rochelle, NY 10801 Toll Free US & Canada: 1 (800) 255-3924 (914) 654-6800 (914) 654-6899 All other Origins: 1 (813) 248-0585 parchem.com [email protected] Collect Calls Accepted Section 2. Hazards Identification Classification of the substance or mixture Classification according to Directive 67/548/EEC or 1999/45/EC as amended: This preparation does not meet the criteria for classification according to Directive 1999/45/EC as amended. Classification according to Regulation (EC) No 1272/2008 as amended: This mixture does not meet the criteria for classification according to Regulation (EC) 1272/2008 as amended. Hazard and precautionary statements Hazard statements: The substance does not meet the criteria for classification. Precautionary statements: Not available. Appearance & Odor: White powder with no odor. Fire & Explosion Hazards Potential for dust explosion may exist. This product is not defined as flammable or combustible. However, the product may decompose under fire conditions to produce toxic oxides of carbon. Depending upon conditions, dusts may be sensitive to static discharge. Avoid possibility of dry powder and friction causing static electricity in presence of flammables (See NFPA-77, Chpt. 6) Primary Route of Exposure: Skin and eye contact are the primary routes of exposure to this product. Inhalation Acute Exposure: Inhalation of dust may cause mild irritation. Skin Contact - Acute: Skin contact is not expected to cause irritation.
    [Show full text]
  • Fine Biocompatible Powders Synthesized from Calcium Lactate and Ammonium Sulfate
    ceramics Article Fine Biocompatible Powders Synthesized from Calcium Lactate and Ammonium Sulfate Maksim Kaimonov 1,* , Tatiana Shatalova 1,2 , Yaroslav Filippov 1,3 and Tatiana Safronova 1,2 1 Department of Materials Science, Lomonosov Moscow State University, Building, 73, Leninskie Gory, 1, 119991 Moscow, Russia; [email protected] (T.S.); fi[email protected] (Y.F.); [email protected] (T.S.) 2 Department of Chemistry, Lomonosov Moscow State University, Building, 3, Leninskie Gory, 1, 119991 Moscow, Russia 3 Research Institute of Mechanics, Lomonosov Moscow State University, Michurinsky pr., 1, 119192 Moscow, Russia * Correspondence: [email protected]; Tel.: +7-952-889-11-43 Abstract: Fine biocompatible powders with different phase compositions were obtained from a 0.5 M solution of ammonium sulfate (NH4)2SO4 and calcium lactate Ca(C3H5O3)2. The powder ◦ after synthesis and drying at 40 C included calcium sulfate dehydrate CaSO4·2H2O and calcite ◦ CaCO3. The powder after heat treatment at 350 C included β-hemihydrate calcium sulfate β- CaSO4·0.5H2O, γ-anhydrite calcium sulfate γ-CaSO4 and calcite CaCO3. The phase composition of ◦ powder heat-treated at 600 C was presented as β-anhydrate calcium sulfate β-CaSO4 and calcite ◦ CaCO3. Increasing the temperature up to 800 C leads to the sintering of a calcium sulfate powder β β consisting of -anhydrite calcium sulfate -CaSO4 main phase and a tiny amount of calcium oxide CaO. The obtained fine biocompatible powders of calcium sulfate both after synthesis and after heat Citation: Kaimonov, M.; Shatalova, treatment at temperature not above 600 ◦C can be recommended as a filler for producing unique T.; Filippov, Y.; Safronova, T.
    [Show full text]
  • Solubilities of Calcium and Zinc Lactate in Water and Water-Ethanol Mixture
    Korean J. Chem. Eng., 18(1), 133-135 (2001) SHORT COMMUNICATION Solubilities of Calcium and Zinc Lactate in Water and Water-Ethanol Mixture Xuejun Cao*, Ho-Joon Lee, Hyun Shik Yun and Yoon-Mo Koo† *State Key Laboratory of Bioreactor Engineering, Department of Biochemical Engineering, East China University of Science and Technology, Shanghai, 200237, China Department of Biological Engineering, Inha University, 253 Yonghyundong, Namku, Inchon, 402-751, Korea (Received 21 August 2000 • accepted 26 December 2000) Abstract−The solubility of lactate salts, L(+) and DL(±) forms of calcium and zinc lactate in water at temperature between 5 and 80 oC, was measured and empirical equations were obtained by regression of solubility-temperature data. The equations can be used to calculate the solubility of calcium and zinc lactate at a given temperature. The change in solubility of L(+) and DL(±) calcium and zinc lactate in water-ethanol mixture at 20 oC was also in- vestigated. The solubilities of calcium and zinc lactate were lowered by the addition of ethanol to the solution. Key words: Solubility, Calcium Lactate, Zinc Lactate INTRODUCTION reached an equilibrium at a given temperature. The attainment of equilibrium was checked by measuring the concentration of sam- Calcium and zinc lactates are important chemicals in the lactic ples every 30 min. Salts were added until they formed precipitates. acid industry, and calcium lactate crystallization is a popular com- Tested temperature range was between 5 and 80 oC with 5 oC in- mercial separation method of lactic acid. Calcium and zinc salts of tervals. If necessary, a short temperature interval was applied.
    [Show full text]
  • Calcium Lactate Fact Sheet
    Calcium Lactate & Calcium Lactate Powder PREVENTATIVE CARE Calcium:2,3 Calcium is the most abundant mineral in the human body, contributing to about 40 percent of the Features of Calcium Lactate: body’s mineral mass. The majority of the calcium exists • Supports absorption of calcium and in the bones and teeth, while the remaining one percent magnesium* is found in intra and extracellular fluids to support • Supports muscle contraction and nerve conduction metabolic functions. Sufficient dietary calcium intake is • Supports maintenance and function required throughout the lifespan as bones in your body of cell membranes and membrane are continuously remodeling. Calcium plays a role in permeability vascular function, muscle health, immune function, nerve • Supports blood coagulation communication, intracellular signaling and hormonal • Supports proper functioning of secretion. It binds with phospholipids and gamma- enzyme systems linolenic acids — a type of fat — to support the blood •Supports and helps maintain healthy clotting mechanism. The body maintains tight controls of bone density and remodeling blood calcium; if inadequate, it will utilize calcium from •Highly soluble form of calcium from a the bones. nondairy source •Contains a 5:1 ratio of calcium and magnesium •Provides additional support for the Supplement Facts Available immune system response function Serving Size: 6 Tablets Sizes: Servings per Container: 15, 55, or 133 •Adequate calcium as part of a healthful . • Calcium Lactate diet, along with physical activity, may 90 Tablets reduce the risk of osteoporosis in Amount per Serving % Daily Value • Calcium Lactate later life.* Calories 5 Total Carbohydrate 1g <1%* 330 Tablets Calcium 250mg 19% • Calcium Lactate Magnesium 50mg 12% 800 Tablets .
    [Show full text]
  • CALCIUM-SANDOZ® Novartis Consumer Health Calcium Preparations Calcium Therapy Indications and Clinical Uses: As a Dietary Suppl
    CALCIUM-SANDOZ® Novartis Consumer Health Calcium Preparations Calcium Therapy Indications And Clinical Uses: As a dietary supplement where calcium intake may be inadequate: childhood and adolescence, pregnancy and lactation, postmenopausal females and in the aged. In the treatment of calcium deficiency states which may occur in diseases such as: tetany of the newborn (as a supplement to parenterally administered calcium), hypoparathyroidism (acute and chronic), pseudo-hypoparathyroidism, postmenopausal and senile osteoporosis, rickets and osteomalacia. Contra-Indications: Hypercalcemia and hypercalciuria (e.g. hyperparathyroidism, vitamin D overdosage, decalcifying tumors such as plasmocytoma, bone metastases); severe renal disease; and in calcium loss due to immobilization. Hypersensitivity to any of the components of Calcium-Sandoz. Although no concrete evidence is available about the metabolic process leading from calcium glucono-galacto-gluconate to galactose, it is advisable not to administer to galactosemic patients. Precautions: For diabetic patients, consideration should be given to the sucrose content of 719 mg/tablet of Calcium-Sandoz Forte. Gramcal and Calcium-Sandoz Syrup are suitable for sodium and potassium restricted diets. Calcium-Sandoz Forte is suitable for potassium restricted diets. Because of the presence of sodium (12 mmol), Calcium-Sandoz Forte is not suitable for sodium restricted diets. In mild hypercalciuria (exceeding 300 mg/24 hours) as well as in chronic renal failure, or where there is evidence of stone formation in the urinary tract, adequate checks must be kept on urinary calcium excretion. If necessary the dosage should be reduced or calcium therapy discontinued. In patients prone to formation of calculi in the urinary tract an increased fluid intake is recommended.
    [Show full text]
  • 24 May 2016 Agen
    EUROPEAN COMMISSION HEALTH AND FOOD SAFETY DIRECTORATE-GENERAL Ares (2016) 2537654 Standing Committee on Plants, Animals, Food and Feed Section Animal Nutrition 23 MAY 2016 - 24 MAY 2016 CIRCABC Link: https://circabc.europa.eu/w/browse/e360a1b3-c86e-4696-8122-f8c95d0412c5 AGENDA Section A Information and/or discussion A.01 Feed Additives - Applications under Regulation (EC) No 1831/2003 Art. 4 or 13. (MP) New applications (copies). A.02 Feed Additives - Applications under Regulation (EC) No 1831/2003 Art. 9. (MP + AR + WT) Discussion on EFSA Scientific Opinions on the safety and efficacy of : A.02.1. a natural mixture of dolomite plus magnesite and magnesium- phyllosilicates (Fluidol) as feed additive for all animal species - Annex A.02.2. Friedland clay (montmorillonite–illite mixed layer clay) when used as a technological additive for all animal species - Annex A.02.3. malic acid, sodium malate and calcium malate for all animal species - Annex A.02.4. propionic acid, sodium propionate, calcium propionate and ammonium propionate for all animal species - Annex A.02.5. formic acid, ammonium formate and calcium formate for all animal species - Annex A.02.6. lactic acid and calcium lactate for all animal species - Annex A.02.7. sodium benzoate as silage additive - Annex Created: 04-05-2016 14:58:28 Page 1 A.02.8. acetic acid, sodium diacetate and calcium acetate for all animal species - Annex A.02.9. sorbic acid and potassium sorbate for all animal species - Annex A.02.10. citric acid for all animal species - Annex A.02.11. concentrated liquid L-lysine (base), L-lysine monohydrochloride and L- lysine sulphate produced using different strains of Corynebacterium glutamicum for all animal species based on a dossier submitted by AMAC/EEIG A.02.12.
    [Show full text]
  • Quintessenz Journals
    pyri Co gh Not for Publicationt b y Q u i N n o t t r f e o Remineralisation of Enamel Subsurface Lesions by Xylitol Chewingssence Gum Containing Calcium Hydrogen Phosphate and Funoran Xiao Ling WANG1, Ye Hua GAN2, Yao GE1, Chuo Yue CHENG1, Xiao Chi CHEN1, Wen Hui WANG1, Bo Xue ZHANG1 Objective: To investigate the effects of xylitol chewing gum containing calcium hydrogen phos- phate and funoran (a polysaccharide extracted from seaweed) on initial enamel lesions. Methods: The clinical trial of the study was double blind. Human enamel blocks with artifi- cial subsurface lesions were mounted in oral devices in 15 subjects. The subjects served as their own controls and were instructed to chew the three different gums, containing: (1) 79% su- crose (S), (2) 40% xylitol (X) and (3) 40% xylitol plus calcium hydrogen phosphate and funo- ran (X+2), 7 times daily, for a period of 1 week each respectively. Mineral content within the lesions after chewing each gum was analysed by quantitative microradiography. All data were analysed statistically using a one-way ANOVA test. Results: After chewing the gums, the amount of mineral at all depths of subsurface lesion was highest in the X+2 group, followed by the X group and then the S group. The difference be- tween the groups was statistically significant (p < 0.01), especially in the lesion body. Conclusion: Xylitol chewing gum containing calcium hydrogen phosphate and funoran sig- nificantly enhanced the remineralisation of initial human enamel lesions in situ. Key words: calcium hydrogen phosphate, enamel subsurface lesion, funoran, remineralisa- tion, xylitol chewing gum ylitol is generally considered to be non-cariogenic explain the caries-inhibitory effects of xylitol as a total Xas it is not fermented by oral bacteria.
    [Show full text]
  • Calcium Supplementation in Pregnant Women
    WORLD HEALTH ORGANIZATION DEPARTMENT OF NUTRITION FOR HEALTH AND DEVELOPMENT EVIDENCE AND PROGRAMME GUIDANCE UNIT Calcium supplementation in pregnant women This submission was prepared by Dr Luz Maria De-Regil with technical input from Dr Matthews Mathai, Dr Juan Pablo Pena-Rosas and Harinder Chahal. EML Section 27 – Vitamins and Minerals Table of contents Acronyms and abbreviations........................................................................................................... 2 Executive summary......................................................................................................................... 3 I. Background and rationale for the application.......................................................................... 4 II. Background on calcium and gestation ................................................................................. 4 1. Public health relevance ........................................................................................................ 4 2. Current public health interventions...................................................................................... 5 3. Proposed public health intervention..................................................................................... 5 III. Methods................................................................................................................................ 5 1. Methods for the assessment of dosing, efficacy and safety ................................................. 5 3. Methods for the assessment of
    [Show full text]
  • The Calcium Challenge
    HEALTHY INGREDIENTS 45 The global market for bone health foods is now worth US$2.5Bn, and is expected to grow at over 4% per annum1. Here DR. GERHARD GERSTNER, technical service manager special salts for Jungbunzlauer Ladenburg GmbH, discusses important technological as well as economical aspects of calcium fortification in dairy products with a focus on micronised tricalcium citrate DAIRY PRODUCTS: the calcium challenge s everybody knows that dairy age of 50 are affected by an en- Calcium joins a range of products usually contain substantial hanced bone fragility and an increased fracture risk. ingredients that add value to Aamounts of calcium, they have been and During the conference, experts agreed to further in- dairy products still are an ideal food to be fortified with extra calcium crease efforts such as optimising diagnostics and treat- to meet nutritional needs by providing larger amounts ment and promoting adequate intake of calcium and in one single serving. vitamin D in the diet. However, the feasibility of calcium addition has to Looking at the ingredients list of dairy products, it be considered as technologically milk products repre- is evident that there is not a single source of calcium sent a complex food matrix. This challenge drives but rather a range of different possibilities which can mineral salt suppliers such as Jungbunzlauer to offer be used commercially: a range of different calcium salts to be able to tune ■ inorganic salts like calcium chloride, calcium car- them to food manufacturers’ applications: tricalcium bonate and calcium phosphate; citrate, calcium gluconate and the new product de- ■ milk minerals comprised mainly of calcium phos- velopment calcium lactate gluconate.
    [Show full text]