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Subject Code: 1DS1010204 Subject Title: Oral Pathology and Oral Microbiology

Pre-requisite Subject - NONE -

Teaching Scheme (Hours per Evaluation Scheme (Marks) week) Theory(T) Practical (P) Viva University Continuous Total Lecture Tutorial Practical Credit University Continuous Voce Total Assessment Assessment Marks Assessment Assessment Marks 90 10 100 2 -- 2 -- 70 10 20 100

Topics for III Year Description 1. Classification of Odontogenic, Etiopathogenesis, BENIGN AND clinical features, histopathology, radiological MALIGNANT features & laboratory diagnosis (as appropriate) ODONTOGENIC of the following common tumours :- - - TUMOURS OF Odontogenic tumours -Classification Benign ORAL CAVITY a. Odontogenic epithelium without odontogenic ectomesenchyme Ameloblastoma, Calcifying Epithelial OdontogenicTumour,AdenomatoidOdonto genicTumour,SquamousOdontogenictumo ur b. Odontogenic epithelium with Odontogenic ectomesenchyme Ameloblastic fibroma, Ameloblastic fibroodontoma, Odontoma, Dentinogenic Ghost cell Tumour c. Odontogenic ectomesenchyme with or without included odontogenic epithelium- Peripheral and Central odontogenic fibroma, Odontogenic Myxoma, Benign ceme ntoblastoma

Malignant a. Odontogenic carcinomas: Metastasizing ameloblastoma, Ameloblastic carcinoma

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2. BENIGN AND Classification of Non-Odontogenic Tumours MALIGNANT - Non-odontogenic NON- a.- Benigntumours of epithelial tissue origin ODONTOGENIC -Papilloma, Keratoacanthoma, Nevus TUMOURS OF b.- Premalignant lesions and conditions: ORAL CAVITY Definition, Classification -Epithelial dysplasia -, Carcinoma in situ, , c. Malignant tumors of epithelial tissue origin -Basal cell carcinoma, Epidermoid carcinoma (Epidemiology, etiology, clinical& histological features, Grading and TNM staging),, Malignant melanoma, Recent advances in diagnosis , management and prevention of Oral cancer d. -Benign tumours of Connective tissue origin -Fibroma, Giant cell fibroma, Peripheral and Central ossifying fibroma, Lipoma, Haemangioma (different types), Lymphangioma,Chondroma,Osteoma,Osteoi dosteoma,Benignosteoblastoma,Tori and Multiple exostosese. Tumour like lesions of Connective tissue origin-,Peripheral ossifying fibroma e-Malignant tumours of Connective tissue origin - Fibrosarcoma,Chondrosarcoma,Kaposi’ssarc oma,Ewing’ssarcoma,Osteosarcoma,Hodgkin ’s and Non Hodgkin’s lymphoma, Burkitt’slymphoma, Multiplemyeloma, Solitary Plasma cell myeloma f-.Benigntumours of Muscle tissue origin - Leiomyoma,Rhabdomyoma,Congenital of newborn, Granular cell tumour g. Benign and Malignant tumours of Nerve tissue origin -Neurofibroma and Neurofibromatosis , Schwannoma, Melanotic neuroectodermal tumour of infancy, Malignant Schwannoma. h. Metastatic tumours of Jaws and Soft tissues of Oral cavity

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BENIGN AND Classification of Salivary Gland Tumours 3. MALIGNANT Salivary Gland Benign neoplasms - Pleomorphic SALIVARY Adenoma, Warthin'stumour, &Oncocytoma. GLAND Malignant neoplasms –Malignant Pleomorphic TUMOURS adenoma Adenoid Cystic Carcinoma, Mucoepidermoid Carcinoma, Acinic Cell Carcinoma & Adenocarcinomas

4. CYSTS OF THE Classification, etiopathogenesis, clinical features, ORAL & histopathology, laboratory & radiological features PARAORAL (as appropriate) of Odontogenic cysts- REGION Odontogenickeratocyst,Dentigerouscyst,Primordi alcyst,Dental lamina cyst of newborn, of adults,Lateral periodontal cyst,Calcifyingodontogeniccyst,Radicular cyst Non-Odontogenic cysts- Pseudocysts of jaws,Aneurysmal bone cyst, & soft tissue cysts of oral ¶oral region.

5. NON , Sialosis, , Xerostomia NEOPLASTIC & Ptyalism. Sjogren’s syndrome ,Benign SALIVARY lymphoepithelial lesion, Necrotizing GLAND sialometaplasia DISEASES : 6. MICROBIAL Microbiology, defence mechanisms including INFECTIONS OF immunological aspects, oral manifestations, ORAL SOFT histopathogy and laboratory diagnosis of common TISSUES bacterial, viral & fungal infections namely :- Bacterial : Scarlet fever, Diphtheria, Tuberculosis, Syphilis, Actinomycoses& its complications – Cancrum Oris, Tetanus, . Viral :, Varicella zoster, Measles, & HIV infection and Oral manifestation of AIDS. Fungal: Candidiasis, Histoplasmosis Immunological diseases: Recurrent Aphthous FDS, SPU-Visnagar

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, Bechet’s syndrome, Reiter’s syndrome, Sarcoidosis. 7. COMMON Etiopathogenesis, clinical features, radiological & NONINFLAMMA laboratory values in diagnosis of: Fibrous TORY DISEASES dysplasia, Cherubism, Osteogenesis Imperfecta, INVOLVING Paget's bone disease, Cleidocranial dysplasia, THE JAWS Rickets, Achondroplasia, Marfan's syndrome , Down's syndrome and Histiocytosis X disease.

8. BIOPSY,CYTOL Factors affecting healing of wounds -healing of OGY AND extraction wound and Dry socket Biopsy- HEALING OF techniques, Healing of biopsy wound -Exfoliative ORAL WOUNDS cytology-Indications, Staining and Interpretation 9. SYSTEMIC Brief review & oral manifestations, diagnosis & DISEASES significance of common Blood, Nutritional, INVOLVING Hormonal & Metabolic diseases of Oral cavity. ORAL CAVITY a. Blood dyscrasias- Clinico-pathological aspects and oral manifestations of Anemias, Polycythemia, Leukopenia, Neutropenia, Agranulocytosis, ChediakHigashi syndrome, Leukocytosis, Infectiousmononucleosis, Leukemias, Purpura Haemophilia b.Oral aspects of Disturbances in mineral metabolism c.Oral aspects of Avitaminosis and Hypervitaminoses d.Oral Aspects of Endocrine dysfunction

10. MUCOCUTANE Etiopathogenesis, clinical features & OUS LESIONS histopathology of the following common lesions. , Lupus Erythematosus, &Pemphigoid lesions, Erythema Multiforme, Psoriasis, Scleroderma, Ectodermal Dysplasia, Epidermolysis bullosa& . 11. PERIODONTAL Stains, Calculus, Dental plaque Etiopathogenesis, DISEASES microbiology, clinical features, histopathology & radiological features (as appropriate) of , gingival enlargements ,ANUG, chronic periodontitis and juvenile periodontitis. Basic immunological mechanisms of to be highlighted. 12. DISEASES OF Ankylosis, luxation and subluxation, summary of TM JOINT different types of arthritis & other developmental malformations, traumatic injuries & myofascial pain dysfunction syndrome 13. DISEASES OF Facial neuralgias – Trigeminal, Sphenopalatine & THE NERVES Glossopharyngeal neuralgias, VII nerve paralysis, FDS, SPU-Visnagar

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Causalgia Psychogenic facial pain & . 14. PIGMENTATION Pigmentation of Oral & Paraoral region & OF ORAL Discolouration of teeth: Causes & clinical TISSUES manifestations. 15. DISEASES OF Traumatic injuries to sinus, Sinusitis, Cysts & MAXILLARY Tumours involving antrum SINUS 16 PRINCIPLES OF Introduction, definition, aims & scope. Sex and BASIC ethnic (racial) differences in tooth morphology FORENSIC and histological age estimation Determination of ODONTOLOGY sex & blood groups from buccal mucosa / saliva. Dental DNA methods Bite marks, rugae patterns & lip prints Dental importance of poisons and corrosives Overview of forensic medicine and toxicology

LABORATORY/PRACTICAL REQUIREMENTS

Students have to maintain records of laboratory procedures/work done/report of practical: Oral Pathology and Microbiology Identification of the pathologic features of: Microdontic tooth, Macrodontic tooth, Gemination of tooth, Fused teeth, of tooth, , Dens in dente, , , Hypoplastic enamel, Fluorosis, Abrasion, , Fracture tooth, Hypercementosis Histopathologic Examination of the following gross specimens: Papilloma, Fibroma, Torus, Carcinoma of oral structures, Salivary Gland Tumours, Ameloblastoma, Periapical Granuloma,Dentigerous Cyst, Pulp Polyp.

Microbiologic Examination of: Tuberculosis, Actinomycosis, Syphilis, Candidiasis Histopathologic Slides of:

1) Odontogenic tumors 2) Non odontogenic tumors 3) Salivary gland tumors. 4) Odontogenic cysts 5) Microbial diseases 6) Bone lesions 7) Mucocutaneous lesions 8) Dental caries 9) Pulp and periapical lesions

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