Curriculum vitae

Name: F. Ulrich Hartl Address: Max-Planck-Institut für Biochemie, Abteilung Zelluläre Biochemie Am Klopferspitz 18 A, 82152 Martinsried b. München/Germany Tel.: 0049-89-8578 2233 Fax: 0049-89-8578 2211 [email protected] Date/Place of birth: March 10, 1957, Essen/Germany Nationality: German

Education:

1982 M.D., University of Heidelberg 1985 Dr. Med., University of Heidelberg, Laboratory of Prof. H. Schimassek at the Institute of Biochemistry. Title: The Regulation of Rat Liver Peroxisomal Metabolism by Thyroid Hormones. 1990 Dr. Med. Habil., University of Munich, Institute of Physiological Chemistry, Chair of Prof. W. Neupert. Title: Topogenesis of Mitochondrial Proteins: Mechanisms of Sorting and Assembly of Proteins into the Mitochondrial Subcompartments. 1985-1986 Postdoctoral Fellow in the laboratory of Prof. W. Neupert at the Institute of Physiological Chemistry, University of Munich. 1989-1990 Postdoctoral Fellow in the laboratory of Prof. W. Wickner, University of California at Los Angeles, Fellow of the Deutsche Forschungsgemeinschaft (German Research Council).

Professional Appointments:

1987-1990 Group leader, Institute of Physiological Chemistry, University of Munich 1991-1992 Associate Member, Program in Cellular Biochemistry & Biophysics, Sloan- Kettering Institute, New York, Associate Professor of Cell Biology and Genetics, Cornell University, Graduate School of Medical Sciences, New York 1993-1997 Member (with tenure), Program in Cellular Biochemistry and Biophysics, Sloan-Kettering Institute, New York, Professor of Cell Biology and Genetics, Cornell University, Graduate School of Medical Sciences, New York 1994-1997 Associate Investigator, Howard Hughes Medical Institute 1997-present Director at Max-Planck-Institut für Biochemie, Martinsried, Germany Honors and Awards:

1985 Summa cum laude, University of Heidelberg 1994 Howard Hughes Appointment 1995 Appointment to William E. Snee Chair of Cellular Biochemistry at Sloan- Kettering Institute, New York 1996 Vinci Award, LVMH Science for Art competition 1997 Lipmann Award of the American Society of Biochemistry and Molecular Biology 1997 Honorary Professor, University of Munich 1997 Foreign Member of the Academy of Science of Nordrhein-Westfalen 1998 EMBO Member 1999 Academy Prize of the Academy of Science of Berlin-Brandenburg 2000 Wilhelm Vaillant Research Prize 2000 Foreign Honorary Member of the American Academy of Arts and Sciences 2002 Gottfried Wilhelm Leibniz-Prize of the Deutsche Forschungsgemeinschaft (German Research Council) 2002 Member Leopoldina, German Academy of Sciences 2003 Feldberg Prize, UK 2004 Member of the Bavarian Academy of Sciences 2004 Gairdner Foundation International Award, Canada 2005 Ernst Jung-Prize for Medicine 2006 Stein and Moore Award of the Protein Society, USA 2006 Koerber European Science Award 2007 Wiley Prize in Biomedical Sciences, Rockefeller University, USA 2008 Lewis S. Rosenstiel Award, Brandeis University, USA 2008 Louisa Gross Horwitz Prize, Columbia University, USA 2008 Honorary Member, Japanese Biochemical Society 2009 Otto Warburg Medal of the German Society for Biochemistry and Molecular Biology (GBM) 2010 Election to AAAS Fellow 2010 Van Gysel Prize for Biomedical Research in Europe, Belgium 2010 Heineken Prize for Biochemistry and Biophysics, Royal Netherlands Academy of Arts and Sciences 2010 Order of Merit of the Federal Republic of Germany 2011 Foreign Associate of the National Academy of Sciences, USA 2011 Lasker Award for Basic Medical Research, New York, USA 2011 Massry Prize, Los Angeles, USA 2011 Heinrich Wieland-Prize of the Boehringer Ingelheim Foundation 2012 Elected Fellow of the American Academy of Microbiology 2012 Shaw Prize in Life Science and Medicine, Hong-Kong 2013 Award of ERC Synergy grant 2013 Herbert Tabor Award of ASBMB, USA 2013 Biochemical Analytic Prize, German Society for Clinical Chemistry and Laboratory Medicine (DGKL) 2014 The Linacre Lecturer, St John’s College, Cambridge 2014 Doctor of Science honoris causa, La Trobe University, Melbourne 2015 Sigman Lecture Award, UCLA 2015 Wenner-Gren Distinguished Lecturer, Wenner-Gren Foundation, Stockholm 2015 IUBMB Lecture Award, FOABMB, Hyderabad

Editorial Board, Reviewing and other Professional Activities:

1994 - 1999 Executive Editor, Biological Chemistry 1994 - 03/2004 Member of Editorial Board, Chemistry and Biology 1995 - 02/2004 Member of Editorial Board, Structure 1995 - 1997 Member of Editorial Board, Cell Stress and Chaperones Member of NIH Study Section 'Molecular Cytology' since 1996 Member of Editorial Board, The Journal of Cell Biology 1998 - 2003 Member of Editorial Board, Protein Science 1998 - 2001 Member of the Advisory Board of the German Society for Biochemistry and Molecular Biology 1999 - 2005 Member of Editorial Board, Current Biology since 1999 Member of Editorial Board, The EMBO Journal 2000 - 01/2006 Editor in Chief, Biological Chemistry 2000 - 03/2010 Member Editorial Board, EMBO Reports 2000 - 2005 Elected reviewer of the Deutsche Forschungsgemeinschaft (German Research Council) 2001 - 06/2008 Member of the Advisory Board of Nature Reviews Molecular Cell Biology 2001 - 2003 Vice President of the German Society for Biochemistry and Molecular Biology 2003 - 2005 President of the German Society for Biochemistry and Molecular Biology 2003 - 06/2005 Vice Chairman of the Biomedical Section of the Max Planck Society since 2004 Member of the Editorial Committee, The Annual Review of Biochemistry since 2004 Speaker of the International Max Planck Research School for Molecular and Cellular Life Sciences, Martinsried 2005 - 07/2008 Chairman of the Biology/Medicine Section of the Max Planck Society since 2006 Member of the Gairdner Medical Advisory Board 2006 - 2011 Executive Editor, Biological Chemistry since 07/2006 Member Editorial Board, Molecular Cell since 2007 Member Board of Trustees, Caesar Research Institute, Bonn since 2009 Member Board of Directors, Feldberg Foundation, U.K. since 2009 Chairman of Scientific Advisory Board, Proteostasis Therapeutics, USA since 2012 Member of Editorial Board, Biological Chemistry since 2012 Member of Editorial Board, Proceedings of the National Academy of Sciences (PNAS) since 2013 Member Selection Committee for the Shaw Prize in Life Science and Medicine

Selected Talks since 2004

2004 Mini-symposium “In Vivo Protein Quality Control” at the Royal Swedish Academy of Science, Stockholm, Sweden 2004 University of Oxford, U.K., Feldberg Lecture 2006 Protein Society Meeting, Stein and Moore Award-Lecture, San Diego, USA 2007 Keynote Lecture, 63rd Harden Conference – Protein Folding, Ambleside/Lake District, UK 2008 37th Annual Lewis S. Rosenstiel Award-Lecture, Brandeis University, Waltham, Massachusetts, USA 2008 Annual Astbury Lecture, University of Leeds, UK 2008 Louisa Gross Horwitz Prize Lecture, Columbia University, New York, USA 2009 Keynote Lecture, EMBO-FEBS Workshop on Cellular Protein Homeostasis in Disease and Ageing, Dubrovnik, Croatia 2009 Otto Warburg Lecture, Trinational GBM Fall Meeting, Aachen, Germany 2010 Annual Cynthia Ann Chan Memorial-Lecture at the University of California, Berkeley, USA 2010 Perspective Lecture at University of Frankfurt and Sanofi-Aventis, Frankfurt, Germany 2011 Keynote Lecture, Cell Stress Conference, Quebec, Canada 2011 Keynote Lecture, CSH Asia Conference on Chaperones and Proteostasis, Suzhou, China 2011 Fawcett Lecture, Harvard Medical School, Boston, USA 2011 Heinrich Wieland Lecture, University of Munich 2012 Keynote Lecture, FASEB Conference, Protein Folding and Assembly in the Cell, Saxtons River, Vermont 2012 Shaw Lecture, Hong Kong University of Science and Technology 2012 David Sears Memorial Lecture, Yale Medical School 2013 ‘Pioneers in the Life Sciences’ –Lecture, University of Heidelberg 2013 Keynote Lecture, FASEB Conference, Molecular Mechanisms and Physiological Consequences of Protein Aggregation, Big Sky, Montana 2013 Invited Lecturer at HFSP Meeting, Strasbourg 2014 Robert F. Furchtgott Lecture, SUNY Downstate, New York 2014 Linacre Lecture, St John’s College, Cambridge 2015 Sigman Lecture, UCLA, Los Angeles 2015 Keynote Lecture Gordon Conference on Stress Proteins in Growth, Development and Disease, Lucca, Italy 2015 Wenner-Gren Distinguished Lectures at Gothenburg and Stockholm Universities 2015 IUBMB Lecture at FOABMB Conference in Hyderabad, India

May, 2016