DOCSLIB.ORG

Research Report 2015 / 2016 Scientific Advisory Board

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Research Report 2015 / 2016 Scientific Advisory Board RESEARCH REPORT 2015 / 2016 SCIENTIFIC ADVISORY BOARD Prof. Dr. Karl-Heinz Altmann Prof. Dr. Stefan Offermanns Institut für Pharmazeutische Max-Planck-Institut für Herz- und Wissenschaften, ETH Zürich Lungenforschung, Bad Nauheim (seit 01 / 2012) (seit 01 / 2016) Prof. Dr. Nils Brose Prof. Dr. Petra Schwille (Vorsitzender) Max-Planck-Institut für Biochemie, Max-Planck-Institut für Experimentelle Martinsried Medizin, Göttingen (seit 01 / 2012) (seit 01 / 2012) Prof. Dr. Rebecca Wade Prof. Dr. Ulrike Eggert (Stellvertretende Vorsitzende) Randall Division of Cell and Molecular Heidelberg Institute for Theoretical Biophysics, King´s College London Studies, HITS gGmbH (seit 01 / 2013) (seit 01 / 2013) Dr. Matthias Gottwald Bayer Pharma AG, Berlin (seit 01 / 2016) Prof. Dr. Thomas Gudermann Walter-Straub-Institut für Pharmakologie und Toxikologie, Ludwig-Maximilians-Universität München (seit 01 / 2013) Prof. Dr. Eckart Gundelfinger Leibniz-Institut für Neurobiologie, Magdeburg (seit 01 / 2013) Prof. Dr. Gerhard Klebe Institut für Pharmazeutische Chemie, Universität Marburg (seit 01 / 2009) Prof. Dr. Beat Meier Laboratorium für Physikalische Chemie, ETH Zürich (seit 01 / 2013) Stichtag 31.12.2016 RESEARCH REPORT 2015 / 2016 2 RESEARCH REPORT FORSCHUNGSBERICHT 2015 / 2016 CONTENTS INHALT PREFACE Interview with Director Dorothea Fiedler VORWORT What's new at the FMP? Was ist neu am FMP? 4 RESEARCH HIGHLIGHTS The cause of muscle weakness reveals the organisational principle in cells AKTUELLES AUS Ursache von vererbter Muskelschwäche aufgeklärt 8 DER FORSCHUNG Milestone for Parkinson's research: The amyloid protein α-synuclein is visualised in the cell for the first time Meilenstein für die Parkinson-Forschung: Amyloid-Protein α-synuclein erstmals in Zelle sichtbar gemacht 9 Double mechanism confirmed: How inositol pyrophosphates alter proteins Doppelter Mechanismus bestätigt: Wie Inositol-Pyrophosphate Proteine verändern 10 Interview with Thomas J. Jentsch "We've pushed the door wide open to novel biomedical insights" „Wir haben die Tür für neue biomedizinische Erkenntnisse aufgestoßen“ 11 CONTENTS INHALT 3 RESEARCH GROUPS Section Molecular Physiology and Cell Biology FORSCHUNGSGRUPPEN Bereich Molekulare Physiologie und Zellbiologie 14 Physiology and Pathology of Ion Transport Thomas J. Jentsch 20 Molecular Pharmacology and Cell Biology Volker Haucke 24 Protein Trafficking Ralf Schülein 28 Molecular Cell Physiology Ingolf E. Blasig 31 Molecular Neuroscience and Biophysics Andrew J.R. Plested 34 Membrane Traffic and Cell Motility Tanja Maritzen 37 Proteostasis in Aging and Disease Janine Kirstein 40 Behavioural Neurodynamics Tatiana Korotkova / Alexey Ponomarenko 43 Molecular and Theoretical Neuroscience Alexander Matthias Walter 46 Cellular Imaging Burkhard Wiesner / Dmytro Puchkov 49 Animal Facility Natali Wisbrun 52 Section Structural Biology Bereich Strukturbiologie 54 Molecular Biophysics Adam Lange 60 NMR-Supported Structural Biology Hartmut Oschkinat 64 Solution NMR Peter Schmieder 68 Computational Chemistry / Drug Design Ronald Kühne 71 Structural Bioinformatics and Protein Design Gerd Krause 74 In-Cell NMR Philipp Selenko 77 Molecular Imaging Leif Schröder 79 NMR Hartmut Oschkinat / Peter Schmieder 82 Section Chemical Biology Bereich Chemische Biologie 86 Chemical Biology II Christian P. R. Hackenberger 92 Chemical Biology I Dorothea Fiedler 96 Peptide-Lipid Interaction / Peptide Transport Margitta Dathe 100 Mass Spectrometry Eberhard Krause 103 Medicinal Chemistry Marc Nazaré 106 Screening Unit Jens Peter von Kries 109 Peptide Synthesis Rudolf Volkmer 112 APPENDIX All Research Groups 116 ANHANG Map Campus Berlin Buch 118 Administrative and Technical Services 120 Imprint 4 RESEARCH REPORT FORSCHUNGSBERICHT 2015 / 2016 WAS IST NEU AM FMP? WHAT´S NEW AT THE FMP? Prof. Dr. Dorothea Fiedler Director at Leibniz-Forschungsinstitut für Molekulare Pharmakologie Dorothea Fiedler has been director at the FMP since July are trying to decode cellular processes at the molecular level. For me as 2015. In an interview, she speaks about her move from the a chemist that's really exciting. One focus of our work are the so-called USA to Germany, the focus of her research and about current inositol pyrophosphates. These molecules are messenger substances in developments at the FMP. the cell that, for example, play an important role in disorders of fat meta- bolism and insulin secretion, but also have an influence on cell migration, Professor Fiedler, you were a distinguished scientist in the specifically metastasis. In effect we are trying to understand the language USA, latterly at Princeton University, and have received of chemistry and thus hope to lay the foundations for new therapies. numerous awards. What motivated your move to Berlin-Buch? There were several reasons. The most important one was undoubtedly Is it the promise of new therapies that motivates you to conduct that the FMP is an excellent institute, where interdisciplinary research basic research? is conducted at the interface of biology and chemistry. To this extent, The desire to improve the health of humankind is fundamental to all of us. the science at the institute was a perfect match. In addition, I can Admittedly, most of the groups at the FMP are not developing therapies collaborate with outstanding people here, both internally and exter- in an actual sense, but it is the basic research conducted at the Institute nally. And then the FMP offers exceptional research conditions. All of that paves the way. This can be seen, for example, in the fact that two this was simply too tempting for me to turn down the offer of a W3S spin-offs from the Hackenberger and Kühne groups are in preparation. professorship linked to the post of director, although I was very happy in the USA. One-third of the research groups at the FMP are junior groups. What's new here? Together with Professor Volker Haucke you form a dual lead- A great deal. In the field of molecular physiology and cell biology, ership at the FMP. How do you divide up this important task? there is a new liaison group, “Neurosciences”, the Emmy Noether There was a clear agreement that I would officially take over the Junior Group led by Alexander Walter. In addition, our junior group management after 18 months. That is now the case as of 1 January, leader Andrew Plested has been offered a Heisenberg professorship but we continue to complete many tasks together and always consult at the Humboldt University. His group will remain at the FMP as each other on important decisions. a guest group for an additional five years. In contrast, we will have to say farewell to Philipp Selenko this year. He has successfully led You are responsible for 300 employees. Is there any time left a junior group in structural biology for several years and has now to do your own research in the laboratory? accepted an attractive offer from the Weizmann Institute of Science Unfortunately, it has been a while since I ran experiments in the in Israel. It is all the more pleasing that a new junior group at the laboratory. But at this point, my co-workers can carry out the work interface of NMR and Cryo-EM is to be established in this better than me. But naturally I still work closely with my PhD important field of research, this being within the context of the students and postdocs. Research is and will certainly remain the planned “Cryo-EM infrastructure”, in which the Berlin Universities part of my work that I enjoy the most. and the MDC will also be involved. Our doctoral students are very successful as well, for instance Jean-Philippe Demers from the What does a professor of chemical biology conduct research on? department of Adam Lange received the Raymond Andrew Prize and In many areas of cell biology we have now arrived at a point where we the Otto Hahn Medal in 2015, a really remarkable accomplishment. WHAT'S NEW AT THE FMP? WAS IST NEU AM FMP? 5 Matthias Schnurr, Honor Rose, Jabadurai Jayapaul Our junior group leader Leif Schröder established a co- I think, and I can speak for the past and for the future, that the operation with the California Institute of Technology in Pasadena FMP is an institute that places special value on modern methods to develop ultra-sensitive magnetic resonance imaging, which and technology. With this strategy, and of course driven by our allows to detect tumours, for example. At the same time, last excellent scientists, we will in the long run secure pioneering results year, he secured a Reinhart Koselleck-Project of the Deutsche that will be of benefit to the scientific community and ultimately Forschungsgemeinschaft (DFG) for a similar undertaking. The to society. What I would like to see is more international visibility. funding amounts to 1.525 million euros and was the first ever The FMP is very well connected throughout Germany and also Koselleck Project for the Leibniz Association. I find all of this quite internationally. Nevertheless, the Institute, like the Leibniz Association, outstanding. is not yet as well known internationally as other German research organisations. We're working on that. At the beginning of this year, there was then a second Reinhart Koselleck-Project for the FMP and a small sensation for the Dorothea Fiedler ist seit Juli 2015 Direktorin am FMP. Im Institute? Interview spricht sie über ihren Wechsel von den USA nach That's right, just a few months later, Volker Haucke impressed the Deutschland, ihre Forschungsschwerpunkte und über aktuelle DFG with his application for research into neuronal communication. Entwicklungen am FMP. We are very proud of that. Both awards show the high level of research at the FMP. As early as 2015, Philipp Selenko and Andrew Plested Frau Professor Fiedler, Sie waren in den USA, zuletzt an der were awarded the prestigious “Consolidator Grant” of the European Universität Princeton, eine angesehene Wissenschaftlerin Research Council (ERC) for their research work. Over the past five und haben etliche Auszeichnungen erhalten. Was hat Sie years, Thomas J. Jentsch successfully applied for these most prominent nach Berlin-Buch verschlagen? and coveted programmes offered by the European Commission, for his Es waren mehrere Gründe.
Load more

Recommended publications
  • Max-Planck-Institut Für Biochemie Max Planck Institute of Biochemistry
    max-planck-institut für biochemie max planck institute of biochemistry MF | 1 Kontakt Contact Max-Planck-Institut für Biochemie Am Klopferspitz 18 D - 82152 Martinsried Tel.: + 49 (89) 8578 - 0 Fax: + 49 (89) 8578 - 3777 Öffentlichkeitsarbeit Anja Konschak Tel.: + 49 (89) 8578 - 2824 Fax: + 49 (89) 8578 - 2943 E-Mail: [email protected] Inhalt Contents Forschungsziele Aims of Research 4-5 Daten und Fakten Facts and Figures 6-7 Die Max-Planck-Gesellschaft The Max Planck Society 8-9 Strukturforschung Structural Research 10-11 Molekulare Strukturbiologie Molecular Structural Biology 12-13 Molekulare Mechanismen der DNA-Reparatur Molecular Mechanisms of DNA Repair 14-15 Zelluläre Strukturbiologie Structural Cell Biology 16-17 Modellierung von Proteinkomplexen Modeling of Protein Complexes 18-19 Zelluläre Biochemie Cellular Biochemistry 20-21 Chaperonin-vermittelte Proteinfaltung Chaperonin-Assisted Protein Folding 22-23 Strukturbiologie der Zilien Structural Biology of Cilia 24-25 Zellbiologie, Signal übertragung Cell Biology, Signal und Regulation Transduction and Regulation 26-27 Molekulare Grundlagen des Proteintransports Molecular Basis of Protein Trafficking 28-29 Molekulare Medizin Molecular Medicine 30-31 Molekulare Mechanotransduktion Molecular Mechanotransduction 32-33 Chromosomale Organisation und Dynamik Chromosome Organization and Dynamics 34-35 Molekulare Zellbiologie Molecular Cell Biology 36-37 Proteinanalytik Protein Analysis 38-39 Proteomics und Signaltransduktion Proteomics and Signal Transduction 40-41 Chromatin-Biologie
    [Show full text]
  • Thomas Jentsch Leibniz-Forschungsinstitut Für Molekulare Pharmakologie (FMP) Max Delbrück Center for Molecular Medicine (MDC) Robert-Rössle-Str
    Thomas Jentsch Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) Max Delbrück Center for Molecular Medicine (MDC) Robert-Rössle-Str. 10 D-13125 Berlin Phone: +49 (0)30 94062961 Email: jentsch(at)fmp-berlin.de Curriculum vitae Since 2009 Deputy director, FMP, Berlin Since 2006 Head, Department of Physiology and Pathology of Ion Transport, FMP/MDC, Berlin Since 2006 Full professor (W3), Charité, Berlin 2001 – 2003 Director, Center for Molecular Neurobiology Hamburg (ZMNH), Hamburg 1995 – 1998 Director, Center for Molecular Neurobiology Hamburg (ZMNH), Hamburg 1993 – 2006 Full professor (C4), Center for Molecular Neurobiology Hamburg (ZMNH), Hamburg 1991 Venia legendi (Habilitation) in Cell Biochemistry, Universität Hamburg 1988 – 1993 Research group leader, Center for Molecular Neurobiology Hamburg (ZMNH), Hamburg 1986 – 1988 Postdoctoral fellow, Whitehead Institute for Biomedical Research, Cambridge, US 1984 MD (Dr. med.), Freie Universität Berlin 1982 PhD in Physics, Fritz-Haber-Institute, Max Planck Society (MPG), Berlin 1981 – 1985 Staff scientist, Department for Clinical Physiology, Freie Universität Berlin 1972 – 1980 Studies in Medicine and studies in Physics, Freie Universität Berlin Research fields Our group is active in the field of physiology and pathology of ion transport with the major areas: § Cellular and molecular mechanisms of neurodegeneration, epilepsy, sensory biology § Cell biology and (patho) physiology of cell volume regulation and related signaling in the CNS § Mouse models § Intracellular trafficking,
    [Show full text]
  • Dr. Gerald Haug Version: February 2020
    Curriculum Vitae Prof. (ETHZ)* Dr. Gerald Haug Version: February 2020 Name: Gerald H. Haug Born: 14 April 1968 in Karlsruhe, Germany Major Scientific Interests: Paleoclimatology, Marine Geology, Paleoceanography, Climate and Societies Gerald Haug is a paleoclimatologist, marine geologist and paleoceanographer. He studies the development of the Earth climate over thousands to millions of years. He analyses sediment cores from the sea floor and lakes, amongst several other climate archives. The chemical composition of the different sediment layers provides clues to the prevailing climatic conditions at the time of deposition. This allows quantitative reconstructions of past climate conditions and the underlying processes in the ocean, atmosphere and climate system. Academic and Professional Career since 2020 President of the Deutsche Akademie der Naturforscher Leopoldina – German National Academy of Sciences, Halle (Saale) since 2015 Ordinary Professor for Climate Geochemistry, Swiss Federal Institute of Technology (ETH) Zurich, Switzerland since 2015 Director, Dept. Climate Geochemistry, Max-Planck-Institute for Chemistry, Mainz, Germany 2007 - 2015 Ordinary Professor for Climate Geology, ETH Zurich, Switzerland 2003 - 2007 Professor (C4), University of Potsdam and Geoforschungszentrum Potsdam (GFZ), Germany 2002 Habilitation in Geosciences, ETH Zurich, Switzerland 2000 - 2002 Oberassistent, ETH Zurich, Switzerland 1998 - 1999 Research Assistant Professor, University of Southern California, Los Angeles, USA Nationale Akademie der Wissenschaften
    [Show full text]
  • Pavel Levkin Is Granted Heinz Maier-Leibnitz Prize
    Press Release No. 034 | or | April 2, 2015 Pavel Levkin Is Granted Heinz Maier-Leibnitz Prize Highest Distinction in Germany for Young Researchers – Polymer Chemist Develops Novel Materials for Molecular Cell Biology Monika Landgraf Chief Press Officer Kaiserstraße 12 76131 Karlsruhe, Germany Phone: +49 721 608-47414 Fax: +49 721 608-43658 E-mail: [email protected] Pavel Levkin (Photo: Markus Breig/KIT) The chemist Dr. Pavel Levkin of Karlsruhe Institute of Technol- ogy (KIT) is granted the 2015 Heinz Maier-Leibnitz Prize by the German Research Foundation (DFG). The prize is considered the highest distinction for young researchers in Germany. Sci- entific work of Pavel Levkin focuses on the investigation of cell-surface interactions, the development of biofunctional ma- terials and super-water-repellent surfaces as well as on nano- particles for specific medicine and gene transport. A major sci- entific success of Levkin was the synthesis of lipid-like mole- cules for gene modification of cells. “Polymer chemistry develops new synthesis methods for innovative materials with so far unreached properties and has a high potential for future use,” KIT President Professor Holger Hanselka explains. “An important application is molecular cell biology. Based on his excellent understanding of polymer chemistry and biology, Pavel Levkin made major contributions. I am extraordinarily happy that this great achievement is now honored by the important Heinz Maier- Leibnitz Prize.” Page 1 / 3 KIT – University of the State of Baden-Wuerttemberg and National Research Center of the Helmholtz Association www.kit.edu Press Release No. 034 | or | April 2, 2015 The Heinz Maier-Leibnitz Prize is granted annually by the DFG to young scientists for outstanding achievements.
    [Show full text]
  • Curriculum Vitae Professor Dr. F. Ulrich Hartl
    Curriculum Vitae Professor Dr. F. Ulrich Hartl Name: F. Ulrich Hartl Born: 10 March 1957 Academic and Professional Career 2002 Managing Director of the Max‐Planck‐Institut fuer Biochemie, Germany since 1997 Director at the Max‐Planck‐Institut fuer Biochemie, Martinsried, Germany 1994 ‐ 1997 Associate Investigator, Howard Hughes Medical Institute 1993 ‐ 1997 Member (with tenure), Program in Cellular Biochemistry and Biophysics, Sloan Kettering Institute, New York, Professor of Cell Biology and Genetics, Cornell University, Graduate School of Medical Sciences, New York, USA 1991 ‐ 1992 Associate Member, Program in Cellular Biochemistry & Biophysics, Sloan‐Kettering Institute, New York, Associate Professor of Cell Biology and Genetics, Cornell University, Graduate School of Medical Sciences, New York, USA 1990 ‐ 1991 “Akademischer Rat” at the Institute of Physiological Chemistry, University of Munich, Germany 1990 Dr. Med. Habil., University of Munich, Institute of Physiological Chemistry, Germany; Chair of Prof. W. Neupert. Title: Topogenesis of Mitochondrial Proteins: Mechanisms of Sorting and Assembly of Proteins into the Mitochondrial Subcompartments 1989 ‐ 1990 Postdoctoral Fellow in the laboratory of Prof. W. Wickner, University of California at Los Angeles, USA; Fellow of the Deutsche Forschungsgemeinschaft (German Research Council) 1987 ‐ 1989 Group leader, Institute of Physiological Chemistry, University of Munich, Germany Nationale Akademie der Wissenschaften Leopoldina www.leopoldina.org 1 1985 ‐ 1986 Postdoctoral Fellow in the
    [Show full text]
  • Hausdorff Chair Peter Scholze Receives the Leibniz Prize December 10, 2015
    HCM 1/2016 HAUSDORFF SPECIALS Hausdorff Chair Peter Scholze receives the Leibniz Prize December 10, 2015 Prof. Dr. Peter Scholze from the Hausdorff Center for Mathematics has been awarded the prestigious Leibniz Price 2015 for his outstanding research achievements. The prize comes with a grant of up to 2.5 million euro, which provides the awardess with great freedom in their research. The mathematician from Bonn is the youngest laureate since the establishment of the prize in 1985. With this prize the DFG appreciates Scholze’s research in the field of arithmetic and algebraic geometry. He is widely colleague Gerd Faltings, who recently received the Shaw recognized for his work on the Langland conjectures. In Prize. Also, Scholze developed new geometric interpreta- 1967, Robert P. Langlands postulated a possible connection tions for spaces that have been first described by his docto- between several research fields. He assumed that this link ral supervisor Michael Rapoport. could help to “translate” several unsolved problems from one field to another in order to solve them there. As a result Peter Scholze is presumably the youngest person to hold a a set of theories about these possible connections were W3-professorhip in Germany and has already established developed, which are now known as the “The Langlands himself as a big name in mathematics. Despite his young Program”. Mathematici- age he has already earned numerous prestigious awards. ans all over the world are In 2015 alone, he already received the Prix Fermat, the working on proving these Ostrowski Prize, the AMS Cole Prize in Algebra and the Conjectures.
    [Show full text]
  • Mathematics People
    people.qxp 4/27/98 3:28 PM Page 1308 Mathematics People as a consultant to numerous high technology firms in Ger- Grötschel Receives Leibniz many and other countries. Prize Grötschel was born in 1948 in Germany. He received his bachelor’s (1971) and master’s (1973) degrees in mathe- Martin Grötschel matics from the University of Bochum. In 1977, he re- has received the 1995 ceived his Ph.D. in economics and in 1981 his habilitation Gottfried Wilhelm in operations research from the University of Bonn. He was Leibniz Prize of the a scientific assistant in Bonn from 1973 until 1982, when Deutsche Forschungs- he was appointed full professor of applied mathematics gemeinschaft (Ger- at the University of Augsburg. Since 1991 he has been full man Science Founda- professor of information technology at the Technical Uni- tion). Thirteen such versity of Berlin, as well as vice president of the Konrad prizes were awarded Zuse Center for Information Technology in Berlin. to German re- Grötschel has received several major prizes for his work, searchers who have including the Fulkerson Prize of the AMS and the Mathe- made outstanding matical Programming Society (1982), the IBM Prize of the contributions to their Institute of Management Science (1984), the Karl Heinz fields, which range Beckurts Prize (1990), and the George B. Dantzig Prize of over mathematics, the the Society for Industrial and Applied Mathematics and the sciences, medicine, Mathematical Programming Society (1991). He has been a and engineering. The member of the Council of the Deutsche Mathematiker- prize consists of a five-year grant of DM 1.5 million (ap- Vereinigung (DMV, German Mathematical Society) since proximately $1 million) for theoretical researchers and 1988 and is a past president of the DMV.
    [Show full text]
  • Virginia Gold 212-626-0505 [email protected]
    acm The Association for Computing Machinery Advancing Computing as a Science & Profession Contact: Virginia Gold 212-626-0505 [email protected] ACM HONORS COMPUTING INNOVATORS FOR ADVANCES THAT BENEFITED RESEARCH, COMMERCE AND EDUCATION Award Winners Recognized for Improvements in Graphics, Information Filtering, Computer Vision, Cryptography, and Educational Opportunities NEW YORK, April 6, 2011 – ACM (the Association for Computing Machinery) today announced the winners of five prestigious awards for their innovations in computing technology that have led to practical solutions for a wide range of challenges facing commerce, education, and society. The awards reflect outstanding achievements that have resulted in expanded geometric applications in computer graphics, personalized recommendations from information filtering, improved face and motion detection, adaptable cryptography methods, and broadened student participation in computer science education. The 2010 ACM award winners, from internationally known research and academic institutions, include practiced innovators as well as promising newcomers to the computing profession. ACM will present these and other awards at the ACM Awards Banquet on June 4, in San Jose, CA. The 2010 ACM awards winners include: • Kurt Mehlhorn, recipient of the Paris Kanellakis Theory and Practice Award for contributions to algorithm engineering that led to creation of the Library of Efficient Data Types and Algorithms (LEDA). This software collection of data structures and algorithms, which Mehlhorn developed with Stefan Näher, provides practical solutions for problems that had previously impeded progress in computer graphics, computer-aided geometric design, scientific computation, and computational biology. LEDA’s software has been incorporated in the applied research programs of thousands of companies worldwide in telecommunications, bioinformatics, Computer-Aided Design (CAD) and Geographic Information System (GIS), banking, optical products, and transportation.
    [Show full text]
  • Gottfried Leibniz Prize Winner Christof Niehrs Is Appointed Founding
    Institute for Molecular Biology (IMB) in Mainz, Germany: Leibniz Prize winner Christof Niehrs appointed founding director The cell and developmental biologist Prof. Dr. Christof Niehrs is the founding director of the new Institute for Molecular Biology (IMB) at the Johannes Gutenberg University in Mainz. And so one of the world's leading bio-scientists will be guide the institute, which is presently under construction and due to go into operation in Spring 2011. “We are delighted that such a distinguished scientist as Professor Niehrs will in charge of the research centre. He has all the qualities required to advance top research in the field of molecular medicine here in Mainz”, as Otto Boehringer, chairman of the board of directors of the Boehringer Ingelheim Foundation, explained. To mark the 125th anniversary of the Boehringer Ingelheim Company in 2010, the Foundation announced the decision to donate 100 Million Euros over a period of 10 years to finance the scientific running of a centre of excellence. The building in which the institute will be accommodated is financed by the federal state of Rhineland-Palatinate. His outstanding scientific achievements have bestowed numerous prizes and distinctions on Professor Niehrs. These include the Gottfried Wilhelm Leibniz Prize from the DFG (German Research Foundation), which is the highest German research award. In his capacity as head of lease the department of Molecular Embryology at the German Cancer Research Center (DKFZ) in Heidelberg, the 48-year old scientist was also recently awarded an “Advanced Grant” of 2.4 e Million Euros from the European Research Council (ERC) for his research.
    [Show full text]
  • Stefan W. Hell
    Prof. Dr. Dr. h.c. mult. Stefan W. Hell Max Planck Institute for Biophysical Chemistry Dept. of NanoBiophotonics Am Fassberg 11 37077 Göttingen, Germany Tel.: +49 551 201 2501 [email protected] Fields of Specialization/Accomplishments • Pioneered physical concepts for breaking the diffraction barrier in a microscope using conventional lenses • Invention and development of STED microscopy and related concepts • Discovered the on-off switching of (fluorescence) signal as key mechanism for overcoming the diffraction resolution limit Qualifications and Positions 1981 – 1987 Physics studies, University of Heidelberg 1990 Doctorate in Physics, University of Heidelberg; Advisor: S. Hunklinger 1991 – 1993 Postdoctoral Researcher, EMBL (European Molecular Biology Laboratory) 1993 – 1996 Principal Scientist, Laser Microscopy Group; University of Turku, Finland 1993 – 1994 Visiting Scientist, Dept. Engineering Science, Oxford University, UK 1996 Habilitation in Physics, University of Heidelberg 1997 – 2002 Group leader, Max Planck Institute for Biophysical Chemistry Göttingen, Germany present Director, Max Planck Institute for Biophysical Chemistry, Göttingen, Head of the Department of NanoBiophotonics; German Cancer Research Center (DKFZ), Heidelberg, Head of the Optical Nanoscopy Division & Adj. Prof., Faculty of Physics, University of Heidelberg Hon. Prof. of Experimental Physics, University of Göttingen Academies 2007 Göttingen Academy of Sciences and Humanities, ord. member 2009 Heidelberg Academy of Sciences and Humanities, corresp. Member 2012
    [Show full text]
  • Awards for Best Bachelor Theses and Dissertation February 4, 2016
    HCM 2/2016 HAUSDORFF SPECIALS Awards for best bachelor theses and dissertation February 4, 2016 The Bonner Mathematische Gesellschaft honors the best ba- chelor students every year with a prize of €250 and a book. The best PhD of the year receives the Hausdorff Memorial Prize of €500 and a book from the Fachgruppe Mathematik. Aras Ergus: „Loop Objects in Pointed Derivators“ This year, Aras Ergus, Daniel Koenen, Tobias Lenz, and advisor: Dr. Moritz Groth Fabian Zaiser received the prize for the best bachelor theses. The Hausdorff Memorial Prize for the best dissertation in Ma- Tobias Lenz: „Gamma-Räume“ thematics was awarded to Dr. Robert Anselm Kucharczyk for advisor: Prof. Dr. Stefan Schwede his thesis „On arithmetic properties of Fuchsian groups and Daniel Koenen: „Subgeometrische Konvergenzraten von Riemann surfaces“. Markovprozessen und eine Anwendung auf SDDEs“ advisor: Prof. Dr. Andreas Eberle Fabian Zaiser: „Massey Products and Configuration Spaces“ advisor: Dr. Thomas Nikolaus www.hausdorff-center.de HAUSDORFF NEWS 2/2016 HAUSDORFF SPECIALS Leibniz Prize awarded to Peter Scholze March 1, 2016 Hausdorff Chair Peter Scholze received the Leibniz Prize at the official ceremony on March 1 in Berlin. Professor Dr. Peter Strohschneider, president of the Deutsche Forschungsgemeinschaft, said in his honorific speech: „Peter Scholze is just 28 years old and is therefore not only the youngest awardee today, but also in the entire 31 year history of the Leibniz Prize.” With the 2.5 million Euro prize money Peter Scholze plans to finance PhD students, postdocs, and conferences, for example. Ada Lovelace Prize for female mathematicians Newsblog of the University of Bonn from March 17, 2016 For the academic year 2015, Dr.
    [Show full text]
  • T Stifle Creativity', Say 1600 Scientists
    news of Otago in molecular reproduction and endocrinology; Richard Randerson, an Anglican priest with a strong record in social German research agency ‘doesn’t issues; and Jacqueline Allan, a medical prac- titioner of Maori descent. stifle creativity’, say 1,600 scientists The opposition National Party has attacked the lack of any panel members with Munich quarter of the 1,600-odd signatories are industrial experience. But Hobbs rejects this, More than 1,600 German scientists have young scientists such as PhD students or saying that “the production community will rallied to the defence of the country’s main postdoctoral researchers. Most are institute be welcome to contribute”. grant-giving agency for basic research, the heads or other well-established researchers. University scientists appear reconciled to Deutsche Forschungsgemeinschaft (DFG). But Jahn, 48, an experienced DFG referee the ban on GMO release, as they have escaped Their action is a response to allegations that and a winner of the agency’s DM3 million the restrictions on laboratory work sought by the agency is reluctant to fund research (US$1.4 million) Leibniz prize for his the Green Party. Researchers can still argue outside the scientific mainstream. research on biological membranes, says for exemptions for non-commercial work, In today’s Nature (see page 922), the that “the time has come for the whole such as the control of possums. But Green- scientists defend the DFG against criticism community to positively affirm the DFG peace and other activists have described the from parts of Germany’s scientific and to protect it against damage”.
    [Show full text]