ISSN-1040-3027, Vol. 37, No. 1 May 2010
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UNITED for People and Animals
NEWS May 2020 - Issue 125 UNITED for people and animals COVID-19 Research Updates Our incredible Journey & Impacts Protect the Animal Free Future Contents CHAIR OF THE BOARD .......................................... 3 FROM OUR PATRON .............................................. 4 MESSAGE FROM CEO ............................................ 5 OUR HISTORY ........................................................ 6 CELEBRATING 50 YEARS ....................................... 8 ARC 1.0 .................................................................10 ARC 2.0 .................................................................11 CURRENT PROJECTS ..........................................12 THE COVID-19 VACCINE PARADOX ..................14 CURRENT PROJECTS: COVID-19 .......................16 REVIEW .................................................................18 MEET THE SAP .....................................................20 PARTNERSHIPS ....................................................22 YOUR IMPACT FOR ANIMALS .............................24 FABULOUS FUNDRAISERS ..................................26 HOW YOU CAN HELP ..........................................28 SHOPPING ...........................................................30 FROM OUR PATRON ............................................31 BOARD OF TRUSTEES CHAIR: Ms Laura-Jane Sheridan VICE CHAIR: Ms Natalie Barbosa TREASURER: Mr Daniel Cameron Dr Christopher (Kit) Byatt Professor Amanda Ellison Ms Julia Jones COMPANY SECRETARY: Ms Sally Luther Animal Free Research UK SCIENTIFIC -
Physiology-2021-Abstract-Book.Pdf (Physoc.Org)
Physiology 2021 Our Annual Conference 12 – 16 July 2021 Online | Worldwide #Physiology2021 Contents Prize Lectures 1 Symposia 7 Oral Communications 63 Poster Communications 195 Abstracts Experiments on animals and animal tissues It is a requirement of The Society that all vertebrates (and Octopus vulgaris) used in experiments are humanely treated and, where relevant, humanely killed. To this end authors must tick the appropriate box to confirm that: For work conducted in the UK, all procedures accorded with current UK legislation. For work conducted elsewhere, all procedures accorded with current national legislation/guidelines or, in their absence, with current local guidelines. Experiments on humans or human tissue Authors must tick the appropriate box to confirm that: All procedures accorded with the ethical standards of the relevant national, institutional or other body responsible for human research and experimentation, and with the principles of the World Medical Association’s Declaration of Helsinki. Guidelines on the Submission and Presentation of Abstracts Please note, to constitute an acceptable abstract, The Society requires the following ethical criteria to be met. To be acceptable for publication, experiments on living vertebrates and Octopus vulgaris must conform with the ethical requirements of The Society regarding relevant authorisation, as indicated in Step 2 of submission. Abstracts of Communications or Demonstrations must state the type of animal used (common name or genus, including man. Where applicable, abstracts must specify the anaesthetics used, and their doses and route of administration, for all experimental procedures (including preparative surgery, e.g. ovariectomy, decerebration, etc.). For experiments involving neuromuscular blockade, the abstract must give the type and dose, plus the methods used to monitor the adequacy of anaesthesia during blockade (or refer to a paper with these details). -
The Use of Non-Human Primates in Research in Primates Non-Human of Use The
The use of non-human primates in research The use of non-human primates in research A working group report chaired by Sir David Weatherall FRS FMedSci Report sponsored by: Academy of Medical Sciences Medical Research Council The Royal Society Wellcome Trust 10 Carlton House Terrace 20 Park Crescent 6-9 Carlton House Terrace 215 Euston Road London, SW1Y 5AH London, W1B 1AL London, SW1Y 5AG London, NW1 2BE December 2006 December Tel: +44(0)20 7969 5288 Tel: +44(0)20 7636 5422 Tel: +44(0)20 7451 2590 Tel: +44(0)20 7611 8888 Fax: +44(0)20 7969 5298 Fax: +44(0)20 7436 6179 Fax: +44(0)20 7451 2692 Fax: +44(0)20 7611 8545 Email: E-mail: E-mail: E-mail: [email protected] [email protected] [email protected] [email protected] Web: www.acmedsci.ac.uk Web: www.mrc.ac.uk Web: www.royalsoc.ac.uk Web: www.wellcome.ac.uk December 2006 The use of non-human primates in research A working group report chaired by Sir David Weatheall FRS FMedSci December 2006 Sponsors’ statement The use of non-human primates continues to be one the most contentious areas of biological and medical research. The publication of this independent report into the scientific basis for the past, current and future role of non-human primates in research is both a necessary and timely contribution to the debate. We emphasise that members of the working group have worked independently of the four sponsoring organisations. Our organisations did not provide input into the report’s content, conclusions or recommendations. -
Articles on Illicit Wildlife Trading in Asia
Articles on Illicit Wildlife Trading in Southeast Asia A Trans-border Wildlife Trade Network Unmasked - Part I HOANG QUOC DUNG Tien Phong Newspaper, Hanoi, Viet Nam [email protected] Translation by Do Oanh, Nguyen Thu Trang and Vu Thi Kim Oanh Located near the remote Ka Tum border gate, connecting Viet Nam’s south western Tay Ninh province with Cambodia, a wildlife breeding farm owned by Tan Hoi Dong Co. Ltd. is well known as one of the country’s first farms to obtain CITES1 certification. However, most people not know that it is also an essential transit site for the most sophisticated and largest trans-border wildlife trafficking network in Viet Nam to date. This network involves forged CITES permits from Lao and inaccurate reporting of macaques actually caught in Cambodia, a country with weak wildlife protection enforcement. According to descriptions in some Vietnamese newspapers, the Tan Hoi Dong’s wildlife farm applies modern technology and scientific processes in their efforts to raise and breed snakes, turtles, and monkeys for use in medical testing and research of vaccines. There has been widespread reporting about the farm after the chairman of an American biological company said in a report on the June 1, 2007 that a group of specialists would go to the Ka Tum border gate to inspect the Tan Hoi Dong farm. Unfortunately, as this series of articles will document, the Tan Hoi Dong company and its associates have long used false documents to import wild animals with their breeding program as a cover for allegedly illegal imports. -
(CCAC) Guide to the Care and Use of Experimental Animals Volume
Canadian Council on Animal Care Conseil canadien de protection des animaux Guide to the Care and Use of Experimental Animals Volume 1, 2nd Edition Sections of this document that have been revised are replaced by links to the relevant documents. The remaining sections are undergoing revision; however, they will continue to be used for CCAC assessments until revised guidelines are published. Editors Dr E.D. Olfert Dr B.M. Cross Mrs A.A. McWilliam Director Asssistant Director Information Officer Animal Resources Centre Animal Resources Centre Canadian Council on Animal Care University of Saskatchewan University of Saskatchewan 1000-151 Slater Street Saskatoon, Saskatchewan Saskatoon, Saskatchewan Ottawa, Ontario K1P 5H3 S7N 0W0 S7N 0W0 In keeping with the CCAC policy of revising statements and guidelines as needed, users of this Guide are encouraged to forward any comments to the Secretariat. Citing certain devices or manufacturers is not to be perceived as the endorsement of the Canadian Council on Animal Care (CCAC) of one particular product over another. Publication Date: 1993 Revision Date: April 2020 © Canadian Council on Animal Care, 1993 ISBN: 0-919087-18-3 Canadian Council on Animal Care 190 O’Connor St., Suite 800 Ottawa, Ontario, K2P 2R3 http://www.ccac.ca Table of Contents TABLE OF CONTENTS DEDICATION ...................................................................................................................1 PREFACE.........................................................................................................................2 -
Animal Experimentation in India
Animal Defenders International ● National Anti-Vivisection Society Animal Experimentation in India Unfettered science: How lack of accountability and control has led to animal abuse and poor science “The greatness of a nation and its moral progress can be judged by the way its animals are treated. Vivisection is the blackest of all the black crimes that man is at present committing against God and His fair creation. It ill becomes us to invoke in our daily prayers the blessings of God, the Compassionate, if we in turn will not practise elementary compassion towards our fellow creatures.” And, “I abhor vivisection with my whole soul. All the scientific discoveries stained with the innocent blood I count as of no consequence.” Mahatma Gandhi Thanks With thanks to Maneka Gandhi and the Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA) of India for their report on the use of animals in laboratories, which has been used for this critique of the state of scientific and medical research in India. Animal Defenders International and the National Anti-Vivisection Society UK fully support and encourage the efforts of the members of India’s CPCSEA to enforce standards and controls over the use of animals in laboratories in India, and their recommendation that facilities and practices in India’s research laboratories be brought up to international standards of good laboratory practice, good animal welfare, and good science. Contributors Jan Creamer Tim Phillips Chris Brock Robert Martin ©2003 Animal Defenders International & National Anti-Vivisection Society ISBN: Animal Defenders International 261 Goldhawk Road, London W12 9PE, UK tel. -
Laboratory Animals and the Art of Empathy D Thomas
197 RESEARCH ETHICS J Med Ethics: first published as 10.1136/jme.2003.006387 on 30 March 2005. Downloaded from Laboratory animals and the art of empathy D Thomas ............................................................................................................................... J Med Ethics 2005;31:197–204. doi: 10.1136/jme.2003.006387 Consistency is the hallmark of a coherent ethical take a big leap of imagination to empathise with the victims of animal experiments as well. In philosophy. When considering the morality of particular short: if we would not want done to ourselves behaviour, one should look to identify comparable what we do to laboratory animals, we should not situations and test one’s approach to the former against do it to them. one’s approach to the latter. The obvious comparator for Animals suffer animal experiments is non-consensual experiments on Crucially for the debate about the morality of people. In both cases, suffering and perhaps death is animal experiments, non-human animals suffer knowingly caused to the victim, the intended beneficiary is just as human ones do. Descartes may have described animals as ‘‘these mechanical robots someone else, and the victim does not consent. Animals [who] could give such a realistic illusion of suffer just as people do. As we condemn non-consensual agony’’ (my emphasis) but no serious scientist experiments on people, we should, if we are to be today doubts that the manifestation of agony is real, not illusory. Indeed, the whole pro-vivisec- consistent, condemn non-consensual experiments on tion case is based on the premise that animals animals. The alleged differences between the two practices are sufficiently similar to us physiologically, and often put forward do not stand up to scrutiny. -
Henry Spira Papers [Finding Aid]. Library of Congress. [PDF Rendered
Henry Spira Papers A Finding Aid to the Collection in the Library of Congress Manuscript Division, Library of Congress Washington, D.C. 2017 Contact information: http://hdl.loc.gov/loc.mss/mss.contact Additional search options available at: http://hdl.loc.gov/loc.mss/eadmss.ms017017 LC Online Catalog record: http://lccn.loc.gov/mm00084743 Prepared by Colleen Benoit, Karen Linn Femia, Nate Scheible with the assistance of Jake Bozza Collection Summary Title: Henry Spira Papers Span Dates: 1906-2002 Bulk Dates: (bulk 1974-1998) ID No.: MSS84743 Creator: Spira, Henry, 1927-1998 Extent: 120,000 items; 340 containers plus 6 oversize ; 140 linear feet ; 114 digital files (3.838 GB) Language: Collection material in English Location: Manuscript Division, Library of Congress, Washington, D.C. Summary: Animal welfare advocate and political activist. Correspondence, writings, notes, newspaper clippings, advertisements, printed matter, and photographs, primarily relating to Spira's work in the animal welfare movement after 1974. Selected Search Terms The following terms have been used to index the description of this collection in the Library's online catalog. They are grouped by name of person or organization, by subject or location, and by occupation and listed alphabetically therein. People Douglas, William Henry James. Fitzgerald, Pegeen. Gitano, Henry, 1927-1998. Grandin, Temple. Kupferberg, Tuli. Rack, Leonard. Rowan, Andrew N. Singer, Peter, 1946- Singer, Peter, 1946- Ethics into action : Henry Spira and the animal rights movement. 1998. Spira, Henry, 1927-1998--Political and social views. Spira, Henry, 1927-1998. Trotsky, Leon, 1879-1940. Trull, Frankie. Trutt, Fran. Weiss, Myra Tanner. Organizations American Museum of Natural History. -
Innovative Delivery of Sirna to Solid Tumors by Super Carbonate Apatite
RESEARCH ARTICLE Innovative Delivery of siRNA to Solid Tumors by Super Carbonate Apatite Xin Wu1,2, Hirofumi Yamamoto1*, Hiroyuki Nakanishi3, Yuki Yamamoto3, Akira Inoue1, Mitsuyoshi Tei1, Hajime Hirose1, Mamoru Uemura1, Junichi Nishimura1, Taishi Hata1, Ichiro Takemasa1, Tsunekazu Mizushima1, Sharif Hossain4,5, Toshihiro Akaike4,5, Nariaki Matsuura6, Yuichiro Doki1, Masaki Mori1 1 Department of Surgery, Gastroenterological Surgery, Graduate School of Medicine, Osaka University, Suita, Japan, 2 Research Fellow of Japan Society for the Promotion of Science, Tokyo, Japan, 3 Nakanishi Gastroenterological Research Institute, Sakai, Japan, 4 Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan, 5 Biomaterials Center for Regenerative Medical Engineering, Foundation for Advancement of International Science, Tsukuba, Japan, 6 Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan * [email protected] Abstract RNA interference (RNAi) technology is currently being tested in clinical trials for a limited OPEN ACCESS number of diseases. However, systemic delivery of small interfering RNA (siRNA) to solid tumors has not yet been achieved in clinics. Here, we introduce an in vivo pH-sensitive de- Citation: Wu X, Yamamoto H, Nakanishi H, livery system for siRNA using super carbonate apatite (sCA) nanoparticles, which is the Yamamoto Y, Inoue A, Tei M, et al. (2015) Innovative Delivery of siRNA to Solid Tumors by Super smallest class of nanocarrier. These carriers consist simply of inorganic ions and accumu- Carbonate Apatite. PLoS ONE 10(3): e0116022. late specifically in tumors, yet they cause no serious adverse events in mice and monkeys. doi:10.1371/journal.pone.0116022 Intravenously administered sCA-siRNA abundantly accumulated in the cytoplasm of tumor Academic Editor: Sung Wan Kim, University of cells at 4 h, indicating quick achievement of endosomal escape. -
“But It's Just a Fish”: Understanding the Challenges of Applying the 3Rs
animals Article “But It’s Just a Fish”: Understanding the Challenges of Applying the 3Rs in Laboratory Aquariums in the UK Reuben Message * and Beth Greenhough School of Geography and the Environment, University of Oxford, Oxford OX1 2JD, UK; [email protected] * Correspondence: [email protected] Received: 29 October 2019; Accepted: 28 November 2019; Published: 3 December 2019 Simple Summary: Fish are widely used in research and some species have become important model organisms in the biosciences. Despite their importance, their welfare has usually been less of a focus of public interest or regulatory attention than the welfare of more familiar terrestrial and mammalian laboratory animals; indeed, the use of fish in experiments has often been viewed as ethically preferable or even neutral. Adopting a social science perspective and qualitative methodology to address stakeholder understandings of the problem of laboratory fish welfare, this paper examines the underlying social factors and drivers that influence thinking, priorities and implementation of fish welfare initiatives and the 3Rs (Replacement, Reduction and Refinement) for fish. Illustrating the case with original stakeholder interviews and experience of participant observation in zebrafish facilities, this paper explores some key social factors influencing the take up of the 3Rs in this context. Our findings suggest the relevance of factors including ambient cultural perceptions of fish, disagreements about the evidence on fish pain and suffering, the language of regulators, and the experiences of scientists and technologists who develop and put the 3Rs into practice. The discussion is focused on the UK context, although the main themes will be pertinent around the world. -
The Case Against Animal Experiments
The Case Against Animal Experiments Animal experiments are both unethical and unscientific. Animals in laboratories endure appalling suffering, such as being deliberately poisoned, brain-damaged and subjected to inescapable electric shocks. The pain and misery inflicted on the victims is enough, on its own, to make vivisection worthy of public condemnation. But animal “ “ experiments are also bad science, since the results they produce cannot be reliably translated to humans. They therefore offer little hope of advancing medical progress. The Case Against Animal Experiments outlines the suffering of animals used in research, before providing a clear, non-technical description of the scientific problems S E with vivisection. L I www.animalaid.org.uk C I N I M O D © How animals are used Contents Each year around four million How animals are used .......................... 1 animals are experimented on inside British laboratories. The suffering of animals in Dogs, cats, horses, monkeys, laboratories ........................................ 2 rats, rabbits and other animals Cruel experiments .................................... 2 are used, as well as hundreds A failing inspection regime ........................ 3 of thousands of genetically Secrecy and misinformation ...................... 4 modified mice. The most The GM mouse myth ................................ 4 common types of experiment The scientific case against either attempt to test how animal experiments .............................. 5 safe a substance is (toxicity Summary ............................................... -
Animals in Science Regulation Unit Annual Report 2015
Animals in Science Regulation Unit Annual Report 2017 © Crown copyright 2018 This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. To view this licence, visit http://nationalarchives.gov.uk/doc/open-government- licence/version/3/ or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: [email protected]. Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. ISBN: 978-1-78655-740-7 © Crown copyright 2018 This publication is licensed under the terms of the Open Government Licence v3.0 except where otherwise stated. To view this licence, visit http://nationalarchives.gov.uk/doc/open-government- licence/version/3/ or write to the Information Policy Team, The National Archives, Kew, London TW9 4DU, or email: [email protected]. Where we have identified any third party copyright information you will need to obtain permission from the copyright holders concerned. ISBN: 978-1-78655-757-5 Contents Ministerial foreword 4 Section 6: Inspection 19 Inspection 19 Foreword 5 Baseline setting 19 Risk management 20 Section 1: What the Animals in Science Regulation Inspector training and continuous professional Unit does 7 development 20 The Policy and Administration Group 7 Inspection reporting 21 Investigating allegations made to the Animals in Science Regulation Unit 21 Section 2: The regulatory framework 9 Judicial Reviews 9 Section 7: Compliance 22