CURRICULUM VITAE

Melody Yue Zeng

EDUCATION 2007-2012 Ph.D. Microbiology and Immunology Indiana University-Purdue University Indianapolis (IUPUI), Indianapolis, Indiana

2002-2006 B.S., cum laude Majors: Biochemistry (Honors) and Psychology Stony Brook University, Stony Brook, New York

AWARDS AND FELLOWSHIPS 2012 IUSM Travel Fellowship 2012 Nature Conference Travel Award 2010-2011 NIH Pre-doctoral T32 Fellowship (Immunology and Infectious Disease) 2009 IUSM Travel Fellowship 2009 Gordon Research Seminar Travel Award 2005-2006 WISE (Women in Science and Engineering) Mentor Fellowship Stony Brook University, New York 2002-2003 WISE Fellowship, Stony Brook University, New York 2002-2003 New York State Commencement Award

TEACHING/MENTORING EXPERIENCE Spring 2009 Laboratory Instructor Microbiology for Nursing Students (J210) Indiana University School of Medicine, Indianapolis, Indiana

Spring 2005 Laboratory Instructor Advanced Molecular Biology (Bio 310) Department of Biochemistry Stony Brook University, Stony Brook, New York

2005-2006 Mentor (with 4 first-year WISE mentees) Women in Science and Engineering (WISE) Program Stony Brook University, Stony Brook, New York

PRESENTATIONS 2012 Abstract presentation “Efferocytosis induces macrophages to produce IL-4 and activate invariant NKT cells to suppress inflammation” Nature Review Immunology Conference – Resolving Inflammation: Mechanisms and Drug Discovery, Oxford, United Kingdom

2012 Poster presentation “Efferocytosis induces macrophages to produce IL-4 and activate invariant NKT cells to suppress inflammation” Keystone Conference-Biology of Cytokines, Keystone, Colorado

2012 Poster presentation “Efferocytosis induces macrophages to produce IL-4 and activate invariant NKT cells to suppress inflammation” Midwest Blood Club, Indianapolis, Indiana

2011 Oral presentation “Role for macrophage NADPH oxidase in clearance of apoptotic neutrophils” Annual Immunology Retreat, Washington University in St. Louis, Missouri

2011 Poster presentation “Role for macrophage NADPH oxidase in clearance of apoptotic neutrophils” American Association of Immunologists Meeting, San Francisco, California

2010 Poster presentation “Rac Regulation of Phagocyte NADPH Oxidase: More to the Story than p67phox” Society of Leukocyte Biology Meeting, Vancouver, Canada

2009 Oral presentation (GRS) & poster presentation (GRC) “Rac Regulation of Phagocyte NADPH Oxidase: More to the Story than p67phox” Gordon Research Conference-Phagocytes, New Hampshire

PUBLICATIONS Zeng MY, Pham D, Bagaitkar J, Liu J, Otero K, Shan M, Wynn TA, Brombacher F, Brutkiewicz RR, Kaplan MH*, Dinauer MC*. An efferocytosis-induced, IL-4-dependent macrophage-iNKT cell circuit suppresses sterile inflammation and is defective in murine CGD. *Equal contribution. Submitted

Zeng MY, Marchal CM, Dinauer MC. A mutation in a Rac binding region in gp91phox impairs both assembly of the phagocyte NADPH oxidase on phagosomes and electron transfer for ROS production in neutrophils. Manuscript in preparation

Zeng MY, Dinauer MC. Efferocytosis activates the NADPH oxidase in macrophages to generate ROS required for processing of apoptotic cells. Manuscript in preparation

Troxell BT, Zeng MY, Ming H, Blum JS, Hassan HM, Yang XF. Pyruvate protects Borrelia burgdorferi from hydrogen peroxide killing and enhances infectivity in a murine model of Lyme disease. Submitted

Stallings JD, Zeng (M)Y, Narvaez F, Rebecchi MJ. 2008. Phospholipase C-δ1 is linked to proliferation, DNA synthesis and cyclin E levels. J Biol Chem. 2008 May 16; 283 (20):13992-4001

Du G, Yonekubo J, Zeng (M)Y, Osisami M, and Frohman MA. 2006. Design of expression vectors for RNA interference based on miRNAs and RNA splicing. Federation of European Biochemical Societies (FEBS), 2006 Dec; 273 (23):5421-7