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Huaqiang Team Leader and Principal Research Scientist

+65 6824 7115 [email protected]

Team Leader and Principal Research Scientist, NanoBio Lab, , 2019-present Team Leader and Principal Research Scientist, Institute of Bioengineering and Nanotechnology, Singapore, 2014-2019 Assistant Professor, National University of Singapore, 2006-2013 Postdoctoral Research Fellow, The Scripps Research Institute, USA, 2002-2006

Ph.D. in Organic Chemistry, The State University of New York at Buffalo, USA, 2002 B.S. in Chemical Physics, The University of Science and Technology of , 1996

Publications

1. A. Roy, H. Joshi, R. , J. Shen, F. , A. Aksimentiev and H. Zeng, “Polyhydrazide‐Based Organic Nanotubes as Efficient and Selective Artificial Iodide Channels,” Angewandte Chemie International Edition, 132 (2020) 4836-4843. IF 12.102

2. J. Shen, J. Fan, R. Ye, N. , Y. Mu and H. Zeng, “Polypyridine-Based Helical Amide Foldamer Channels for Rapid Transport of Water and Proton with High Ion Rejection,” Angewandte Chemie International Edition, (2020) DOI: 10.1002/anie.202003512. IF 12.257

3. J. Shen, R. Ye, A. Romanies, A. Roy, F. Chen, C. , Z. and H. Zeng, “An Aquafoldmer-Based Aquaporin-Like Synthetic Water Channel,” Journal of the American Chemical Society, 142 (2020) 10050-10058. IF 14.695

4. H. Zeng, A. Roy, H. Joshi, R. Ye, J. Shen, F. Chen and A. Aksimentiev, “Polyhydrazide-Based Organic Nanotubes as Extremely Efficient and Highly Selective Artificial Iodide Channels,” Angew. Chem. Int. Ed., (2020) DOI: 10.1002/anie.201916287

5. H. Zeng, F. Chen, J. Shen, N. Li, A. Roy, R. Ye, and C. Ren, “Pyridine/Oxadiazole-Based Helical Foldamer Ion Channels with Exceptionally High K+/Na+ Selectivity,” Angew. Chem. Int. Ed., (2019) 10.1002/anie.201906341

6. Y. , Y. , A. L. Connor, D. P. Miller, R. , J. Shen, B. , E. S. Baker, Q. Tang, S. V. S. R. K. Pulavarti, R. Liu, Q. , Z.-l. , T. Szyperski, H. Zeng, X. Li, R. D. Smith, E. Zurek, J. , and B. , “Folding and Assembly of Short α, β, γ-Hybrid Peptides: Minor Variations in Sequence and Drastic Differences in Higher-Level Structures,” J. Am. Chem. Soc., 141 (2019) 14239-14248

7. F. Zeng, F. Liu, L. , S. , J. Shen, N. Li, H. Ren and H. Zeng, “A Pore-Forming Tripeptide as an Extraordinarily Active Anion Channel,” Org. Lett., 21[12] (2019) 4826-4830

Dr. Huaqiang Zeng

8. R. Ye, C. Ren, J. Shen, F. Chen, N. Li, A. Roy, and H. Zeng, “Molecular Ion Fishers as Highly Active and Exceptionally Selective K+ Transporters,” J. Am. Chem. Soc., 141[25] (2019) 9788-9792

9. L. Yuan, J. Shen, R. Ye, F. Chen and H. Zeng, “Structurally Simple Trimesic Amides as Highly Selective Anion Channels,” Chem. Commun., 55 (2019) 4797-4800

10. C. L. Ren, F. Chen, R. J. Ye, Y. S. Ong, H. F. Lu, S. S. Lee, J. Y. Ying and H. Zeng, “Molecular Swings as Extremely Active Ion Transporters,” Angewandte Chemie International Edition, 58[24] (2019) 8034- 8038

11. C. Ren, F. Zeng, J. Shen, F. Chen, A. Roy, S. Zhou, H. Ren and H. Zeng, “Pore-Forming Monopeptides as Exceptionally Active Anion Channels,” Journal of the American Chemical Society, 140 (2018) 8817- 8826

12. C. Ren, X. , A. Roy, J. Shen, S. Zhou, F. Chen, S. F. Yau Li, H. Ren, Y. Y. and H. Zeng, “A Halogen Bond-Mediated Highly Active Artificial Chloride Channel with High Anticancer Activity,” Chemical Science, 9 (2018) 4044-4051

13. J. Li, Y. Huo and H. Zeng, “Combinatorial Identification of a Highly Soluble Phase-Selective Organogelator with High Gelling Capacity for Crude Oil Gelation,” Journal of Materials Chemistry A, 6 (2018) 10196-10200

14. J. T. Li, Y. P. Huo and H. Q. Zeng, “Polar Solvent-Induced Unprecedented Supergelation of (Un)Weathered Crude Oils at Room Temperature,” Langmuir, 34 (2018) 8058-8064

15. J. Li, M. Liu, Y. Huo and H. Zeng, “DMSO-Accelerated Rapid Gelation of Crude Oils at Room Temperature,” Supramolecular Chemistry, 30 (2018) 1011-1016

16. S. , L. Zeng, G. , L. and H. Q. Zeng, “Ni/Co-Based Metal-Organic Frameworks as Electrode Material for High Performance Supercapacitors,” Chinese Chemical Letters, (2018) DOI: 10.1016/j.cclet.2018.1010.1018

17. J. , L. J. Wang, J. , P. P. Wang, X. J. Wang, G. L. , H. Zeng, J. Li and J. F. , “Structurally Diverse Sesquiterpenoids from the Endangered Ornamental Plant Michelia Shiluensis,” Journal of Natural Products, 81 (2018) 2195-2204

18. J. Shen, C. L. Ren and H. Q. Zeng, “Surprisingly High Selectivity and High Affinity in Mercury Recognition by H-Bonded Cavity-Containing Aromatic Foldarands,” Journal of the American Chemical Society, 139 (2017) 5387-5396

19. C. L. Ren, J. Shen and H. Q. Zeng, “Combinatorial Evolution of Fast-Conducting Highly Selective K+- Channels via Modularly Tunable Directional Assembly of Crown Ethers,” Journal of the American Chemical Society, 139 (2017) 12338-12341

20. C. L. Ren, J. Shen, F. Chen and H. Q. Zeng, “Rapid Room-Temperature Gelation of Crude Oils by a Wetted Powder Gelator,” Angewandte Chemie International Edition, 56 (2017) 3847-3851

21. H. Zhao, J. Shen, C. Ren, W. Zeng and H. Zeng, “A Foldamer-Based Organocatalyst for Direct Arylations of Unactivated Arenes,” Organic Letters, 19 (2017) 2190-2193

22. J. Li, Y. Huo, M. Liu and H. Q. Zeng, “Phase-Selective Organogelators for Oil Spill Treatment,” Progress in Chemistry, 29 (2017) 617-627 Dr. Huaqiang Zeng

23. K. H. Lee and H. Zeng, “Aptamer-Based ELISA Assay for Highly Specific and Sensitive Detection of Zika NS1 Protein,” Analytical Chemistry, 89 (2017) 12743-12748

24. K. H. Lee and H. Zeng, “A General Double Library SELEX Strategy for Aptamer Selection Using Unmodified Nonimmobilized Targets,” Analytical and Bioanalytical Chemistry, 409 (2017) 5081-5089

25. X. Hu, X. Chen, Y. Zhu, Y. F. , H. Q. Zeng, H. F. Jiang and W. Zeng, “Rh(III)-Catalyzed Carboamination of Propargyl Cycloalkanols with Arylamines via Csp2-H/Csp3-Csp3 Activation,” Organic Letters, 139 (2017) 3474-3477

26. Y. P. Huo and H. Q. Zeng, ““Sticky”-Ends-Guided Creation of Functional Hollow Nanopores for Guest Encapsulation and Water Transport,” Accounts of Chemical Research, 49 (2016) 922-930

27. J. Shen, C. L. Ren and H. Q. Zeng, “Tuning Cation-Binding Selectivity and Capacity via Side Chain- Dependent Molecular Packing in the Solid State,” Chemical Communications, 52 (2016) 10361-10364

28. C. L. Ren, G. H. B. Ng, H. , K.-H. , J. Shen, C. Teh, J. Y. Ying and H. Q. Zeng, “Instant Room- Temperature Gelation of Crude Oil by Chiral Organogelators,” Chemistry of Materials, 28 (2016) 4001-4008

29. C. Ren, F. Chen, F. Zhou, J. Shen, H. and H. Zeng, “Low-Cost Phase-Selective Organogelators for Rapid Gelation of Crude Oils at Room Temperature,” Langmuir, 32 (2016) 13510-13516

30. W.-J. , J. Xiong, W.-X. Wang, H.-Y. Zhang, H. Zeng and J.-F. Hu, “Phlefargesiine A, a C16N2 Lycopodium Alkaloid with an Unprecedented [6/7/6/6]-Tetracyclic Skeleton From Phlegmariurus Fargesii,” Tetrahedron Letters, 57 (2016) 3218-3221

31. C. Li, L. Wu, L. Chen, X. Yuan, Y. , W. Feng, N. Liu, Y. Ren, A. Sengupta, M. S. Murali, P. K. Mohapatra, G. , H. Q. Zeng, S. Ding and L. Yuan, “Highly Efficient Extraction of Actinides With Pillar[5]Arene- Derived Diglycolamides in Ionic Liquids via a Unique Mechanism Involving Competitive Host-Guest Interactions,” Dalton Transactions, 45 (2016) 19299-19310

32. Y. P. Huo, H. Q. Zeng and Y. G. Zhang, “Integrating Metabolic Engineering and Heterogeneous Chemocatalysis: New Opportunities for Biomass to Chemicals,” ChemSusChem, 9 (2016) 1078-1080

33. Y. P. Huo, C. Q. , S. Y. Wang, S. M. Ji, T. F. , L. , N. Cai and H. Q. Zeng, “Color-Tunable Solid- State Emissions of Zn(II) and Cd (II) Complexes Derived from Cyano-Modified 2-Substituted 8- Hydroxyquinolines,” Polyhedron, 119 (2016) 175-183

34. C.-L. Hu, J. Xiong, L.-X. Gao, J. Li, H. Q. Zeng, Y. and J.-F. Hu, “Diterpenoids from the Shed Trunk Barks of the Endangered Plant Pinus Dabeshanensis and their PTP1B Inhibitory Effects,” RSC Advances, 6 (2016) 60467-60478

35. N. Hong, M. Li, Y. Yuan, T. Wang, M. , H. , H. Q. Zeng, J. Song and Y. Hong, “Dnd is a Critical Specifier of Primordial Germ Cells in the Medaka Fish,” Stem Cell Reports, 6 (2016) 411-421

36. Y. Liu, J. Shen, C. , C. L. Ren and H. Q. Zeng, “Intramolecularly Hydrogen-Bonded Aromatic Pentamers as Modularly Tunable Macrocyclic Receptors for Selective Recognition of Metal Ions,” Journal of the American Chemical Society, 137 (2015) 12055-12063

Dr. Huaqiang Zeng

37. X. Li, B. Li, L. Chen, J. Hu, C. , Q. , L. Wu, H. Q. Zeng, B. Gong and L. Yuan, “Liquid-Crystalline Mesogens Based on Cyclo[6]aramides: Distinctive Phase Transitions in Response to Macrocyclic Host- Guest Interactions,” Angewandte Chemie International Edition, 54 (2015) 11147-11152

38. C. Ren, J. Shen and H. Zeng, “One-Pot Synthesis of Strained Macrocyclic Pyridone Hexamers and Their High Selectivity toward Cu2+ Recognition,” Organic Letters, 17 (2015) 5946-5949

39. J. Xiong, Z.-L. Hong, L.-X. Gao, J. Shen, S.-T. Liu, G.-X. Yang, J. Li, H. Q. Zeng and J.-F. Hu, “Chlorabietols A-C, Phloroglucinol-Diterpene Adducts from the Chloranthaceae Plant Chloranthus oldhamii,” The Journal of Organic Chemistry, 80 (2015) 11080-11085

40. S. P. Teong, G. Yi, H. Q. Zeng and Y. Zhang, “The Effects of Emulsion on Sugar Dehydration to 5- Hydroxymethylfurfural in a Biphasic System,” Green Chemistry, 17 (2015) 3751-3755

41. W. L. Ma, C. Q. Wang, J. T. Li, K. Zhang, Y.-J. Lu, Y. P. Huo and H. Q. Zeng, “The Dynamics, Energetics and Selectivity of Water Chain-Containing Aquapores Created by the Self-Assembly of Aquafoldamer Molecules,” Organic & Biomolecular Chemistry, 13 (2015) 10613-10619

42. H. Q. Zhao, S. Sheng, Y. H. Hong and H. Q. Zeng, “Proton Gradient-Induced Water Transport Mediated by Water Wires Inside Narrow Aquapores of Aquafoldamer Molecules,” Journal of the American Chemical Society, 136 (2014) 14270-14276

43. Y. Z. , M. Xu, R. Z. Gao, X. W. Li, F. X. Li, X. D. Wu, D. G. Xu, H. Q. Zeng and L. Yuan, “Two-Component Supramolecular Gels Derived from Amphiphilic Shape-Persistent Cyclo[6]aramides for Specific Recognition of Native Arginine,” Angewandte Chemie International Edition, 53 (2014) 11834-11839

44. J. Shen, W. L. Ma, L. Yu, J.-B. Li, H.-C. Tao, K. Zhang and H. Q. Zeng, “Size-Dependent Patterned Recognition and Extraction of Metal Ions by a Macrocyclic Aromatic Pyridone Pentamer,” Chem. Commun., 50 (2014) 12730-12733

45. H. L. , H. , J. Shen, Y.-J. Lu, B. , K. Zhang and H. Q. Zeng, “An Unusual Macrocyclization Reagent for Highly Selective One-Pot Synthesis of Strained Macrocyclic Aromatic Hexamers,” Chemical Communications, 50 (2014) 3582-3584

46. C. Sun, Y. Liu, J. Q. Liu, Y.-J. Lu, L. Yu, K. Zhang and H. Q. Zeng, “Computational Insights into Processes Underlying the Amine-Induced Fluorescence Quenching of a Stimuli-Responsive Phenol-Based Hexameric Foldamer Host,” Journal of Organic Chemistry, 79 (2014) 2963-2973

47. J. Q. Liu, C. Sun, W. L. Ma, Y.-J. Lu, L. Yu, K. Zhanga and H. Q. Zeng, “A Conformationally Switchable Fluorescent Oligophenol Foldamer for Selective Sensing of Copper(II) Ions,” RSC Advances, 4 (2014) 54469-54473

48. J. C. Hu, L. Chen, J. Shen, J. Luo, P. C. Deng, Y. Ren, H. Q. Zeng, W. Feng and L. H. Yuan, “Convergent Heteroditopic Cyclo[6]Aramides as Macrocyclic Ion-Pair Receptors for Constructing [2]Pseudorotaxanes,” Chemical Communications, 50 (2014) 8024-8027

49. H. Q. Zhao, J. Shen, J. J. , R. J. Ye and H. Q. Zeng, “A Macrocyclic Aromatic Pyridone Pentamer as a Highly Efficient Organocatalyst for the Direct Arylations of Unactivated Arenes,” Chemical Communications, 49 (2013) 2323-2325

Dr. Huaqiang Zeng

50. 4C. Sun, C. L. Ren, Y. C. , B. Qin and H. Q. Zeng, “Patterned Recognition of Amines and Ammonium Ions by a Stimuli-Responsive Foldamer-Based Hexameric Oligophenol Host,” Chemical Communications, 49 (2013) 5307-5309

51. W. Q. Ong and H. Q. Zeng, “Rapid Construction of Shape-Persistent H-Bonded Macrocycles via One- Pot H-Bonding-Assisted Macrocyclization,” Journal of Inclusion Phenomena and Macrocyclic Chemistry, 76 (2013) 1-11

52. H. L. Fu, Y. Liu and H. Q. Zeng, “Shape-Persistent H-Bonded Macrocyclic Aromatic Pentamers,” Chemical Communications, 49 (2013) 4127-4144

53. H. Q. Zhao, W. Q. Ong, F. Zhou, X. , X. Y. Chen, S. F. Y. Li, H. B. Su, N. J. Cho and H. Q. Zeng, “Chiral Crystallization Of Aromatic Helical Foldamers Via Complementarities In Shape And End Functionalities,” Chemical Science, 3 (2012) 2042-2046

54. F. Zhou, H. L. Fu, W. Q. Ong, R. J. Ye, W. X. Yuan, Y. J. Lu, Y. P. Huo, K. Zhang, H. B. Su and H. Q. Zeng, “Locking High Energy 1D Chain Of Dichloromethane Molecules Containing Abnormally Short Cl Center Dot Center Dot Center Dot Cl Contacts Of 2.524 Angstrom Inside Organic Crystals,” Organic & Biomolecular Chemistry, 10 (2012) 5525-5528

55. H. Q. Zhao, W. Q. Ong, X. Fang, F. Zhou, M. N. Hii, S. F. Y. Li, H. B. Su and H. Q. Zeng, “Synthesis, Structural Investigation And Computational Modelling Of Water-Binding Aquafoldamers,” Organic & Biomolecular Chemistry, 10 (2012) 1172-1180

56. W. Q. Ong, H. Q. Zhao, C. Sun, J. E. Wu, Z. C. Wong, S. F. Y. Li, Y. H. Hong and H. Q. Zeng, “Patterned Recognition Of Amines And Ammonium Ions By A Pyridine-Based Helical Oligoamide Host,” Chemical Communications, 48 (2012) 6343-6345

57. H. B. Zhao, N. Hong, W. Q. Lu, H. Q. Zeng, J. X. Song and Y. H. Hong, “Fusion Gene Vectors Allowing for Simultaneous Drug Selection, Cell Labeling, and Reporter Assay in Vitro and in Vivo,” Analytical Chemistry, 84 (2012) 987-993

58. Y. Liu, B. Qin and H. Q. Zeng, “POCl3-Mediated H-Bonding-Directed One-Pot Synthesis Of Macrocyclic Pentamers, Strained Hexamers And Highly Strained Heptamers,” Science China-Chemistry, 55 (2012) 55-63

59. Z. Y. , B. Qin, C. Sun, Y. Liu, X. Zheng, K. Zhang, A. H. Conney and H. Q. Zeng, “Folding-Promoted TBAX-Mediated Selective Demethylation Of Methoxybenzene-Based Macrocyclic Aromatic Pentamers,” Organic & Biomolecular Chemistry, 10 (2012) 4164-4171

60. C. L. Ren, F. Zhou, B. Qin, R. J. Ye, S. Shen, H. B. Su and H. Q. Zeng, “Crystallographic Realization of the Mathematically Predicted Densest All-Pentagon Packing Lattice by C-5-Symmetric “Sticky” Fluoropentamers,” Angewandte Chemie-International Edition, 50 (2011) 10612-10615

61. C. L. Ren, S. Y. Xu, J. Xu, H. Y. Chen and H. Q. Zeng, “Planar Macrocyclic Fluoropentamers as Supramolecular Organogelators,” Organic Letters, 13 (2011) 3840-3843

62. C. Ren, V. Maurizot, H. Q. Zhao, J. Shen, F. Zhou, W. Q. Ong, Z. Y. Du, K. Zhang, H. B. Su and H. Q. Zeng, “Five-Fold-Symmetric Macrocyclic Aromatic Pentamers: High-Affinity Cation Recognition, Ion-Pair- Induced Columnar Stacking, and Nanofibrillation,” Journal of the American Chemical Society, 133 (2011) 13930-13933

Dr. Huaqiang Zeng

63. B. Qin, C. Sun, Y. Liu, J. Shen, R. J. Ye, J. Zhu, X. F. and H. Q. Zeng, “One-Pot Synthesis of Hybrid Macrocyclic Pentamers with Variable Functionalizations around the Periphery,” Organic Letters, 13 (2011) 2270-2273

64. B. Qin, S. Shen, C. Sun, Z. Y. Du, K. Zhang and H. Q. Zeng, “One-Pot Multimolecular Macrocyclization for the Expedient Synthesis of Macrocyclic Aromatic Pentamers by a Chain Growth Mechanism,” Chemistry-an Asian Journal, 6 (2011) 3298-3305

65. B. Qin, W. Q. Ong, R. J. Ye, Z. Y. Du, X. Y. Chen, Y. , K. Zhang, H. B. Su and H. Q. Zeng, “Highly Selective One-Pot Synthesis of H-Bonded Pentagon-Shaped Circular Aromatic Pentamers,” Chemical Communications, 47 (2011) 5419-5421

66. B. Qin, L. Y. Jiang, S. Shen, C. Sun, W. X. Yuan, S. F. Y. Li and H. Q. Zeng, “Folding-Promoted TBACI- Mediated Chemo- and Regioselective Demethylations of Methoxybenzene-Based Macrocyclic Pentamers,” Organic Letters, 13 (2011) 6212-6215

67. W. Q. Ong, H. Q. Zhao, X. Fang, S. Woen, F. Zhou, W. L. Yap, H. B. Su, S. F. Y. Li and H. Q. Zeng, “Encapsulation of Conventional and Unconventional Water Dimers by Water-Binding Foldamers,” Organic Letters, 13 (2011) 3194-3197

68. W. Q. Ong, H. Q. Zhao, Z. Y. Du, J. Z. Y. Yeh, C. L. Ren, L. Z. W. , K. Zhang and H. Q. Zeng, “Computational Prediction and Experimental Verification of Pyridine-Based Helical Oligoamides Containing Four Repeating Units Per Helical Turn,” Chemical Communications, 47 (2011) 6416-6418

69. Z. Y. Du, C. L. Ren, R. J. Ye, J. Shen, V. Maurizot, Y. J. Lu, J. Wang and H. Q. Zeng, “BOP-Mediated One- Pot Synthesis of C-5-Symmetric Macrocyclic Pyridone Pentamers,” Chemical Communications, 47 (2011) 12488-12490

70. Z. Y. Du, H. F. Ng, K. Zhang, H. Q. Zeng and J. Wang, “Ionic Liquid Mediated Cu-Catalyzed Cascade Oxa-Michael-Oxidation: Efficient Synthesis of Flavones Under Mild Reaction Conditions,” Organic & Biomolecular Chemistry, 9 (2011) 6930-6933

71. S. B. Wu, Q. Y. Bao, W. X. Wang, Y. Zhao, G. , Z. Zhao, H. Q. Zeng and J. F. Hu, “Cytotoxic Triterpenoids and Steroids from the Bark of Melia Azedarach,” Planta Medica, 77 (2011) 922-928

72. Y. Yan, B. Qin, C. L. Ren, X. Y. Chen, Y. K. Yip, R. J. Ye, D. W. Zhang, H. B. Su and H. Q. Zeng, “Synthesis, Structural Investigations, Hydrogen-Deuterium Exchange Studies, and Molecular Modeling of Conformationally Stablilized Aromatic Oligoamides,” Journal of the American Chemical Society, 132 (2010) 5869-5879

73. B. Qin, C. L. Ren, R. J. Ye, C. Sun, K. Chiad, X. Y. Chen, Z. Li, F. , H. B. Su, G. A. Chass and H. Q. Zeng, “Persistently Folded Circular Aromatic Amide Pentamers Containing Modularly Tunable Cation- Binding Cavities with High Ion Selectivity,” Journal of the American Chemical Society, 132 (2010) 9564-9566

74. C. L. Fu, W. Chen, Y. L. Quek, R. Y. Ni, A. B. A. Ghani, W. W. Y. Leong, H. Q. Zeng and D. J. , “Sustainability From Agricultural Waste: Chiral Ligands From Oligomeric Proanthocyanidins Via Acid- Mediated Depolymerization,” Tetrahedron Letters, 51 (2010) 6322-6324

75. Y. Yan, B. Qin, Y. L. Shu, X. Y. Chen, Y. K. Yip, D. W. Zhang, H. B. Su and H. Q. Zeng, “Helical Organization in Foldable Aromatic Oligoamides by a Continuous Hydrogen-Bonding Network,” Organic Letters, 11 (2009) 1201-1204 Dr. Huaqiang Zeng

76. T. Y. Zhou, X. M. Li, M. T. T. Ng, Y. F. Wang, N. M. Quek, J. Luo, W. X. Yuan, C. H. Tan, H. Q. Zeng and T. H. Li, “Synthesis and Characterization of Circular Structures of i-Motif Tagged with Fluoresceins,” Bioconjugate Chemistry, 20 (2009) 644-647

77. W. Xu, X. J. Xue, T. H. Li, H. Q. Zeng and X. G. Liu, “Ultrasensitive and Selective Colorimetric DNA Detection by Nicking Endonuclease Assisted Nanoparticle Amplification,” Angewandte Chemie- International Edition, 48 (2009) 6849-6852

78. B. Qin, X. Y. Chen, X. Fang, Y. Y. Shu, Y. K. Yip, Y. Yan, S. Y. Pan, W. Q. Ong, C. L. Ren, H. B. Su and H. Q. Zeng, “Crystallographic Evidence of an Unusual, Pentagon-Shaped Folding Pattern in a Circular Aromatic Pentamer,” Organic Letters, 10 (2008) 5127-5130

79. H. Q. Zeng, J. M. Me and P. G. Schultz, “Genetic Introduction of a Diketone-Containing Amino Acid into Proteins,” Bioorganic & Medicinal Chemistry Letters, 16 (2006) 5356-5359

80. L. H. Yuan, A. R. Sanford, W. Feng, A. M. Zhang, J. Zhu, H. Q. Zeng, K. Yamato, M. F. Li, J. S. Ferguson and B. Gong, “Synthesis of Crescent Aromatic Oligoamides,” Journal of Organic Chemistry, 70 (2005) 10660-10669

81. L. H. Yuan, H. Q. Zeng, K. Yamato, A. R. Sanford, W. Feng, H. S. Atreya, D. K. Sukumaran, T. Szyperski and B. Gong, “Helical Aromatic Oligoamides: Reliable, Readily Predictable Folding from the Combination of Rigidified Structural Motifs,” Journal of the American Chemical Society, 126 (2004) 16528-16537

82. H. Q. Zeng, X. W. Yang, A. L. Brown, S. Martinovic, R. D. Smith and B. Gong, “An Extremely Stable, Self-Complementary Hydrogen-Bonded Duplex,” Chemical Communications(2003) 1556-1557

83. H. Q. Zeng, X. W. Yang, R. A. Flowers and B. Gong, “A Noncovalent Approach to Antiparallel Beta- Sheet Formation,” Journal of the American Chemical Society, 124 (2002) 2903-2910

84. B. Gong, H. Q. Zeng, J. Zhu, L. H. Yuan, Y. H. , S. Z. Cheng, M. Furukawa, R. D. Parra, A. Y. Kovalevsky, J. L. Mills, E. Skrzypczak-Jankun, S. Martinovic, R. D. Smith, C. Zheng, T. Szyperski and X. C. Zeng, “Creating Nanocavities Of Tunable Sizes: Hollow Helices,” Proceedings of the National Academy of Sciences of the United States of America, 99 (2002) 11583-11588

85. H. Q. Zeng, H. Ickes, R. A. Flowers and B. Gong, “Sequence Specificity of Hydrogen-Bonded Molecular Duplexes,” Journal of Organic Chemistry, 66 (2001) 3574-3583

86. R. D. Parra, H. Q. Zeng, J. Zhu, C. Zheng, X. C. Zeng and B. Gong, “Stable Three-Center Hydrogen Bonding in a Partially Rigidified Structure,” Chemistry-a European Journal, 7 (2001) 4352-4357

87. J. Zhu, R. D. Parra, H. Q. Zeng, E. Skrzypczak-Jankun, X. C. Zeng and B. Gong, “A New Class Of Folding Oligomers: Crescent Oligoamides,” Journal of the American Chemical Society, 122 (2000) 4219-4220

88. H. Q. Zeng, R. S. Miller, R. A. Flowers and B. Gong, “A Highly Stable, Six-Hydrogen-Bonded Molecular Duplex,” Journal of the American Chemical Society, 122 (2000) 2635-2644

89. B. Gong, C. Zheng, H. Q. Zeng and J. Zhu, “Polar Assembly Of N,N '-Bis(4-Substituted Benzyl)Sulfamides,” Journal of the American Chemical Society, 121 (1999) 9766-9767

Dr. Huaqiang Zeng

90. B. Gong, Y. F. Yan, H. Q. Zeng, E. Skrzypczak-Jankunn, Y. W. Kim, J. Zhu and H. Ickes, “A New Approach for the Design of Supramolecular Recognition Units: Hydrogen-Bonded Molecular Duplexes,” Journal of the American Chemical Society, 121 (1999) 5607-5608

91. H. Q. Zeng, M. Yang, X. Y. Huang and X. Y. Chen, “The Crystal And Molecular Structure Of The Complex Diaquatetrakis(Imidazole)Copper(II) Terephthalate,” Crystal Research and Technology, 32 (1997) 467-473

92. J. M. Li, H. Q. Zeng and M. Xu, “Spectroscopic Properties Of Cu(L-Met)(2), Cu(DL-Met)(2), Cu(L-Ala)(2) And Cu(DL-Ala)(2)Center Dot H2O And Qualitative Explanations To The Magnetism And Relative Ordering Of The One-Electron Energy Levels,” Spectroscopy Letters, 30 (1997) 545-556

93. J. M. Li, H. Q. Zeng, Y. X. Ke, Q. M. Wang and X. T. Wu, “Synthesis and x-ray crystal structure analysis of Cu-2(CH3CH2COO)(4)(OPph(3))(2),” Crystal Research and Technology, 32 (1997) 475-479

94. J. M. Li, H. Q. Zeng, J. H. Chen, Q. M. Wang and X. T. Wu, “Crystal Structure Of A Flexible Self- Assembled Two-Dimensional Square Network Complex [Cu-2(C3H2O4)(2)(H2O)(2)(4,4'-Bpy)]Center Dot H2O,” Chemical Communications(1997) 1213-1214

Patents

1. H. Q. Zeng, “Highly Selective High-Capacity Cesium Removal Using Macrocycic Aromatic Pentamers”, Singapore Patent Granted in September of 2014

2. H. Q. Zeng, “Highly Selective High-Capacity Cesium Removal Using Macrocycic Aromatic Pentamers”, PCT Patent Granted in September of 2015

3. H. Q. Zeng, C. L. Ren, “Highly Efficient Phase-Selective Organogelators for Oil Spill Cleanup and Reclamation”, Singapore Patent Granted in August of 2015

4. H. Q. Zeng, C. L. Ren, A Powder Gelator and Method to Enhance Gelator's Gelling Speed In The Powder Form”, Singapore Patent Granted in January of 2015

5. H. Q. Zeng, C. L. Ren, “An Organogelator Compound”, PCT Patent Granted in February of 2017

6. H. Q. Zeng, K. H. Lee, “DNA Aptamers for Highly Specific and Sensitive Detection of Zika NS1 Protein in an ELISA Assay”, Singapore Patent Granted in August of 2018

7. H. Q. Zeng, K. H. Lee, “Aptamers for Detection of Flaviviral Protein”, PCT Patent Filed in August of 2018

8. H. Q. Zeng, F. Zeng, “Synthetic Proton Channel and Methods Thereof”, Singapore Patent Granted in January of 2019

9. H. Q. Zeng, A. Roy, F. Chen, J. Shen, “Polyhydrazides-Based Superpermeable Synthetic Water Channels”, Singapore Patent Granted in February of 2019