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Microorganism Solutions C297-E086 Microorganism Species Analysis and Component Analysis – Detection and Identification of Microorganisms and Metabolite Analysis – Shimadzu’s Microorganism Solutions JQA-0376 Founded in 1875, Shimadzu Corporation, a leader in the development of advanced technologies, has a distinguished history of innovation built on the foundation of contributing to society through science and technology. We maintain a global network of sales, service, technical support and applications centers on six continents, and have established long-term relationships with a host of highly trained distributors located in over 100 countries. For information about Shimadzu, and to contact your local office, please visit our Web site at www.shimadzu.com Microorganism SHIMADZU CORPORATION. International Marketing Division 3. Kanda-Nishikicho 1-chome, Chiyoda-ku, Tokyo 101-8448, Japan Solutions Phone: 81(3)3219-5641 Fax. 81(3)3219-5710 URL http://www.shimadzu.com The contents of this brochure are subject to change without notice. AnalysisAnalysis Printed in Japan 3295-12904-15A-NS TotalTotal SolutionsSolutions forfor MicroorganismMicroorganism AnalysisAnalysis andand TestingTesting Shimadzu Supports Everybody Working with Microorganisms While we cannot easily see microorganisms, they are closely linked to our lives. From ancient times, microorganisms have expanded Microorganisms are researched and utilized for a wide range of purposes in many research and industry fields. the human diet by providing fermented foods including alcohol and pickles. In recent years, microorganisms have become The major purposes are inspection and control, identification, searching for new microorganisms, functional investigations, and indispensable in the production of useful substances, such as antibiotics, taste components, and vitamins. Microorganisms are also industrial applications. essential for environmental sustainability and improvements, including wastewater treatment, soil cleanup, and atmospheric balance. Moreover, the application of microorganisms has infinitely extended the possibilities of biotechnologies, which have undergone explosive development since the 1970s. The application of microorganisms also promises solutions to food and energy problems, ResearchResearch aimsaims inin researchresearch andand industryindustry fieldsfields which are the biggest issues facing mankind. Clinical research, hygiene Identification and detection Pharmaceuticals Searching for new microorganisms However, microorganisms can also pose a threat to people. For example, E. coli O157 bacteria that causes food poisoning, norovirus Chemistry Inspection and control (pollution countermeasure) Functional investigations/improvements epidemics, and bacterial contamination of food factories all present serious social problems. In addition, new antibiotic-resistant bacteria such as Methicillin-Resistant Staphylococcus Aureus (MRSA) and emerging viruses present significant medical problems. Detection (investigation of biodegradation, etc.) Extraction of antibiotics and other useful components To gain knowledge of microorganisms, diverse analysis technologies are applied to determine not only how many of what bacteria Extraction of enzymes and other useful components Inspection and control (pollution countermeasures) are where (identification and quantitation) but also for research into the response to bacterial components, bacterial-derived Energy Searching for new microorganisms Foods Fermentation and brewing for food production components, metabolites, and the environment. Environment Functional investigations, functional improvements Detection (disposition kinetics) Shimadzu provides an extensive product range, expertise, and solutions to anyone dealing with microorganisms in a diverse range Analysis of metabolites Inspection and control (pollution countermeasures) of fields, including medicine, foods, chemicals, energy, the environment, clinical medicine, and hygiene. Inspection and control Functional investigations Recovery of metabolites Searching for new microorganisms Observation and Identification Detection of Specific Research into microorganisms is multifaceted, from the observation of microorganisms to the chemical analysis of of Microorganisms Microorganisms microorganism-derived components. Consequently, the most important point is the selection of the optimal research approach and the best instruments to support the research. This document introduces examples of the application of Shimadzu products to these research aims. Workflow for microorganism research Ampdirect Plus Component Observation Identification Detection Other applications DeNOVA-5000HT analysis AXIMA series Norovirus G1/G2 detection reagent kit Basic MultiNA Contents research to BioSpec-nano SPM-9600 applied Aims Target Analytical Instrument/Reagent Page research Observation of Morphology Microscope P. 4 Microorganism Species Identification of Genome Information DeNOVA-5000HT DNA Sequencer P. 6 Microorganism Species Low-Molecular Information LCMS-2020 P. 8 Detection of Specific Nucleic Acid (DNA) Ampdirect Plus P. 10 Microorganisms Nucleic Acid (RNA) Norovirus G1/G2 Detection Reagent Kit P. 12 Analysis of Protein, Peptide, Lipid, etc. MALDI-TOF MS P. 14 Microorganism-Derived Protein MALDI-TOF MS P. 18 Components Amino Acid, Fatty Acid, Organic Acid, etc. GCMS-QP2010 Plus P. 20 Saccharide, Organic Acid, Amino Acid, etc. Prominence HPLC P. 22 Prominence UFLC LCMS-2020 GCMS-QP2010 Plus Amino Acid, Organic Acid, and Aflatoxin Prominence UFLC P. 24 Nucleic Acid, Amino Acid, and Aflatoxin LCMS-2020 P. 26 Analysis of Microorganism Components Other Applications Protein, Peptide, etc. Spectrophotometers P. 30 Metal AA-7000 Series, etc. P. 31 2 3 TotalTotal SolutionsSolutions forfor MicroorganismMicroorganism AnalysisAnalysis andand TestingTesting Shimadzu Supports Everybody Working with Microorganisms While we cannot easily see microorganisms, they are closely linked to our lives. From ancient times, microorganisms have expanded Microorganisms are researched and utilized for a wide range of purposes in many research and industry fields. the human diet by providing fermented foods including alcohol and pickles. In recent years, microorganisms have become The major purposes are inspection and control, identification, searching for new microorganisms, functional investigations, and indispensable in the production of useful substances, such as antibiotics, taste components, and vitamins. Microorganisms are also industrial applications. essential for environmental sustainability and improvements, including wastewater treatment, soil cleanup, and atmospheric balance. Moreover, the application of microorganisms has infinitely extended the possibilities of biotechnologies, which have undergone explosive development since the 1970s. The application of microorganisms also promises solutions to food and energy problems, ResearchResearch aimsaims inin researchresearch andand industryindustry fieldsfields which are the biggest issues facing mankind. Clinical research, hygiene Identification and detection Pharmaceuticals Searching for new microorganisms However, microorganisms can also pose a threat to people. For example, E. coli O157 bacteria that causes food poisoning, norovirus Chemistry Inspection and control (pollution countermeasure) Functional investigations/improvements epidemics, and bacterial contamination of food factories all present serious social problems. In addition, new antibiotic-resistant bacteria such as Methicillin-Resistant Staphylococcus Aureus (MRSA) and emerging viruses present significant medical problems. Detection (investigation of biodegradation, etc.) Extraction of antibiotics and other useful components To gain knowledge of microorganisms, diverse analysis technologies are applied to determine not only how many of what bacteria Extraction of enzymes and other useful components Inspection and control (pollution countermeasures) are where (identification and quantitation) but also for research into the response to bacterial components, bacterial-derived Energy Searching for new microorganisms Foods Fermentation and brewing for food production components, metabolites, and the environment. Environment Functional investigations, functional improvements Detection (disposition kinetics) Shimadzu provides an extensive product range, expertise, and solutions to anyone dealing with microorganisms in a diverse range Analysis of metabolites Inspection and control (pollution countermeasures) of fields, including medicine, foods, chemicals, energy, the environment, clinical medicine, and hygiene. Inspection and control Functional investigations Recovery of metabolites Searching for new microorganisms Observation and Identification Detection of Specific Research into microorganisms is multifaceted, from the observation of microorganisms to the chemical analysis of of Microorganisms Microorganisms microorganism-derived components. Consequently, the most important point is the selection of the optimal research approach and the best instruments to support the research. This document introduces examples of the application of Shimadzu products to these research aims. Workflow for microorganism research Ampdirect Plus Component Observation Identification Detection Other applications DeNOVA-5000HT analysis AXIMA series Norovirus G1/G2 detection reagent kit Basic MultiNA Contents research to BioSpec-nano SPM-9600 applied Aims Target Analytical Instrument/Reagent Page research Observation of Morphology Microscope
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