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Johnson & Johnson Vision Fast Facts

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Johnson & Johnson Vision Fast Facts Johnson & Johnson Vision Fast Facts Unmet Patient Needs Johnson & Johnson Enterprise Capabilities An estimated 253 million people have More than 100 teaching institutions around visual impairment, but 80% can be treated, the world prevented or cured.1 A top 5 global pharmaceutical company4 80% fear losing their sight more than any other sense2 Surgical experience spanning 80 + years Vision is one of the largest and fastest Proven commercial success: 70% of J&J sales growing healthcare categories globally come from products holding the #1 or #2 global ( $71 billion and +5% respectively3 ) market position4 Global Reach Leading Portfolio Best Selling Contact 10,000+ 60MM Lenses in the World, ACUVUE® 5 # Leader in Laser Corrective Eye Employees Patients served Surgery (LASIK)6 Leader in Premium Cataract IOL Implants Leader in Dry Eye Disease 103 11 Medical Device Technology Countries with Manufacturing product presence and R&D sites 1 Addressing Vision Needs Throughout a Patient’s Lifetime Ages 19-34 Ages 8-12 Nearsightedness, Ages 40+ Ages 60+ Nearsightedness Correction Farsightedness & Astigmatism Glaucoma & Dry Eye Cataracts Ages 13-18 Ages 35-44 Ages 45-60 Beauty & Performance Emerging Presbyopia Presbyopia & Cataracts 1Vision Impairment and Blindness. World Health Organization. 2Research!America and the Alliance for Eye and Vision Research (AEVR) 3Syndicated data sources – data on file 4Johnson & Johnson 2015 Investor Fact Sheet 5Euromonitor validated claim 62016 Market Scope - 2016 Refractive Surgery Report: A Global Market Analysis for 2015 to 2021 ACUVUE® is a registered trademark of Johnson & Johnson Vision Care, Inc. © Johnson & Johnson Vision Care, Inc. 2018. The third party trademarks used herein are trademarks of their respective owners. See product indications and important safety information on pages 2 through 6. Product Indications and Important Safety Information Blink Contacts® Lubricating Eye Drops for Soft and Rigid Gas-Permeable ADVERSE REACTIONS (Possible problems and what to do): (RGP) Contact Lenses The following may occur: DESCRIPTION: Blink Contacts® Lubricating Eye Drops is a sterile, • Eyes stinging, burning or itching buffered, isotonic, preserved solution. This aqueous formulation includes • Excessive watering (tearing) of the eyes purified water, sodium hyaluronate, sodium chloride, potassium chloride, • Unusual eye secretions calcium chloride, magnesium chloride and , boric acid and is preserved • Redness of the eyes with OcuPure® preservative (stabilized oxychloro complex 0.005%). • Reduced sharpness of vision (visual acuity) This preparation contains no chlorhexidine, no thimerosal and no other • Blurred vision mercury-containing ingredients. • Sensitivity to light (photophobia) • Dry eyes ACTIONS: Blink Contacts® Lubricating Eye Drops has been formulated for use with both soft and Rigid Gas Permeable (RGP) contact lenses, If you notice any of the above, IMMEDIATELY remove and examine your to rewet lenses before insertion and lubricate lenses during wear and lenses. If a lens appears to be damaged, do not reapply; consult your to moisturize and refresh tired, dry eyes. It also relieves minor irritation, eye care professional. If the problem stops and the lenses appear to be discomfort, dryness, blurring and itchiness, which may occur while undamaged, follow the “Directions” below, before reapplying the lens. wearing your lenses. If the problem continues, IMMEDIATELY remove your lenses, discontinue INDICATIONS: Use Blink Contacts® Lubricating Eye Drops to lubricate use of all lens care products that contact the eye and consult your eye and rewet soft (hydrophilic) and RGP contact lenses, to help relieve care professional. If any of the above occurs, a serious condition such as dryness, discomfort and irritation that may be associated with lens wear infection, corneal ulcer, neovascularization or iritis may be present. Seek and to cushion lenses by placing a drop on the lens prior to application immediate professional identification of the problem and obtain treatment, on the eye. if necessary, to avoid serious eye damage. CONTRAINDICATIONS (Reasons not to use): If you are allergic to DIRECTIONS: TO LUBRICATE AND REWET LENSES DURING THE DAY: any ingredient in Blink Contacts® Lubricating Eye Drops, do not use With the lenses on the eye, apply 1 to 2 drops to each eye as needed or as this product. directed by your eye care professional. Blink several times. FOR EXTRA COMFORT: Place 1 or 2 drops of Blink Contacts® Lubricating Eye Drops on WARNINGS: PROBLEMS WITH CONTACT LENSES AND LENS CARE each side of each lens before application. PRODUCTS COULD RESULT IN SERIOUS INJURY TO THE EYE. It is essential that you follow your eye care professional’s directions and all HOW SUPPLIED: Blink Contacts® Lubricating Eye Drops is supplied in labeling instructions for proper use and care of your lenses and lens sterile 0.06 fl oz (2mL) and 0.34 fl oz (10mL) plastic bottles. The bottles are care products, including the lens case. EYE PROBLEMS, INCLUDING marked with the lot number and expiration date. CORNEAL ULCERS, CAN DEVELOP RAPIDLY AND LEAD TO LOSS OF VISION. Blink® Tears Lubricating Eye Drops USES: For the temporary relief of burning, irritation, and discomfort due to Daily-wear lenses are not indicated for overnight wear and should not be dryness of the eye or exposure to wind or sun. May be used as a protectant worn while sleeping. Clinical studies have shown that the risk of serious against further irritation. adverse reactions is increased when these lenses are worn overnight. WARNINGS: Extended-wear lenses should be regularly removed for cleaning and disinfecting or for disposal and replacement on the schedule prescribed by • For external use only. your eye care professional. • To avoid contamination, do not touch tip of container to any surface. Replace cap after using. Clinical studies have shown that there is an increased incidence of serious • Do not use if solution changes color or becomes cloudy. adverse reactions in extended-wear contact lens users as compared to daily-wear contact lens users. Studies have also shown that the risk of STOP USE AND ASK A DOCTOR IF: You experience eye pain, changes serious adverse reactions increases the longer extended-wear lenses in vision, continued redness or irritation of the eye, or if the condition are worn before removal for cleaning and disinfecting or for disposal worsens or persists for more than 72 hours. and replacement. KEEP OUT OF REACH OF CHILDREN: If swallowed, get medical help or Studies have also shown that smokers had a higher incidence of adverse contact a poison control center right away. reactions. It is recommended that contact lens wearers see their eye care professional once a year or, if directed, more frequently. Blink® Lid Wipes INDICATIONS FOR USE: As part of a daily eye care regimen, follow your To avoid contamination, do not touch the dropper tip of the bottle to any Eye Care Professional’s recommendation and use a cleansing wipe to surface and DO NOT transfer contents to any other bottle or container. remove all the debris and crusting, as well as excessive oil and make-up. Replace cap after using. HOW TO USE BLINK® LID WIPES: Blink® Lid Wipes, with soothing PRECAUTIONS: Keep bottle tightly closed when not in use. For in-eye use chamomile, can be used on children and adults for effective removal of only. Do not use in the lens case. Store at room temperature. Use before debris or other secretions on the eyelid and surrounding area. the expiration date marked on the bottle and carton. Keep out of the reach of children. DIRECTIONS: Always wash and dry your hands thoroughly before using wipe. • Apply Blink® Lid Wipes before instillation of daily contact lens wear and/or use of daily lubricating or rewetting drops. • Remove wipe from sachet. • Close eye and rub gently several times over the eyelid and lashes. symptoms unrelated to cystic meibomian glands and require other medical • Wipe from the nose outward. Always use a fresh wipe for each eye. management. Safety and effectiveness of the device have not been studied • No need to rinse. Discard wipe after use. in patients with these conditions. • To use warm, place the unopened sachet in a cup of warm water for a • Moderate to severe (Grade 2-4) allergic, vernal or giant papillary few minutes. Test the temperature of the wipe before applying to the conjunctivitis eyelid to make sure it is comfortably warm. • Severe (Grade 3 or 4) eyelid inflammation(e.g., blepharochalasis, • To use cold, place the unopened sachet in the refrigerator for a few staphylococcal blepharitis or seborrheic blepharitis). Patients with minutes. Do not freeze. severe eyelid inflammation should be treated medically prior to device use BLINK® LID WIPES IS A GENTLE CLEANSING WIPE THAT IS: • Systemic disease conditions that cause dry eye(e.g., Stevens-Johnson • Rinse free - just wipe and go. syndrome, vitamin A deficiency, rheumatoid arthritis, Wegener’s • Formulated with soothing chamomile. granulomatosis, sarcoidosis, leukemia, Riley-Day syndrome, systemic • Preservative/alcohol free and hypoallergenic. lupus erythematosus, Sjögren’s syndrome) • Conveniently individually packaged for travel and on-the-go use. • Taking medications known to cause dryness (e.g., isotretinoin • Clinically proven, gentle and safe for daily use. (Accutane®) and systemic antihistamines) • Esthetic eyelid and eyelash procedures (e.g., blepharoplasty, lash PRECAUTIONS: extensions, eyelid tattooing) • For external use only. In addition,
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