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Characterization of a Recombinant Modified Vaccinia Virus Ankara Expressing the Severe Acute Respiratory Syndrome Virus 2 Spike Protein
Characterization of a recombinant Modified Vaccinia virus Ankara expressing the severe acute respiratory syndrome virus 2 spike protein von Alina Tscherne, M.Sc. Inaugural-Dissertation zur Erlangung der Doktorwürde (Dr. rer. biol. vet.) der Tierärztlichen Fakultät der Ludwig-Maximilians-Universität München Characterization of a recombinant Modified Vaccinia virus Ankara expressing the severe acute respiratory syndrome virus 2 spike protein von Alina Tscherne, M.Sc. aus Voitsberg (Österreich) München 2021 Aus dem Veterinärwissenschaftlichen Department der Tierärztlichen Fakultät der Ludwig-Maximilians-Universität München Lehrstuhl für Virologie Arbeit angefertigt unter der Leitung von: Univ.-Prof. Dr. Gerd Sutter Mitbetreuung durch: Univ.-Prof. Dr. Asisa Volz Gedruckt mit Genehmigung der Tierärztlichen Fakultät der Ludwig-Maximilians-Universität München Dekan: Univ.-Prof. Dr. Reinhard K. Straubinger, Ph.D. Berichterstatter: Univ.-Prof. Dr. Gerd Sutter Korreferentin: Priv.-Doz. Dr. Simone M.-L. Renner Tag der Promotion: 17. Juli 2021 Für meine Familie Die vorliegende Dissertationsschrift enthält wissenschaftliche Daten, die im Journal Proceedings of the National Academy of Sciences of the United States of America (PNAS) veröffentlicht wurden: Alina Tscherne, Jan Hendrik Schwarz, Cornelius Rohde, Alexandra Kupke, Georgia Kalodimou, Leonard Limpinsel, Nisreen M.A. Okba, Berislav Bošnjak, Inga Sandrock, Sandro Halwe, Lucie Sauerhering, Katrin Brosinski, Liangliang Nan, Elke Duell, Sylvia Jany, Astrid Freudenstein, Jörg Schmidt, Anke Werner, Michelle Gellhorn Sera, Wolfgang Guggemos, Michael Seilmaier, Clemens- Martin Wendtner, Reinhold Förster, Bart L. Haagmans, Stephan Becker, Gerd Sutter, Asisa Volz “Immunogenicity and efficacy of the COVID-19 candidate vector vaccine MVA-SARS-2-S in preclinical vaccination”, erschienen am 13.07.2021 (doi: 10.1073/pnas.2026207118.) Table of Contents VI TABLE OF CONTENTS I. -
Psychological Status and Behavior Changes of the Public During the COVID-19 Epidemic in China
Liu et al. Infectious Diseases of Poverty (2020) 9:58 https://doi.org/10.1186/s40249-020-00678-3 RESEARCH ARTICLE Open Access Psychological status and behavior changes of the public during the COVID-19 epidemic in China Xi Liu1†, Wen-Tao Luo1,2†, Ying Li1,3†, Chun-Na Li1, Zhong-Si Hong1, Hui-Li Chen1, Fei Xiao1 and Jin-Yu Xia1* Abstract Background: A cluster of pneumonia cases were reported by Wuhan Municipal Health Commission, China in December 2019. A novel coronavirus was eventually identified, and became the COVID-19 epidemic that affected public health and life. We investigated the psychological status and behavior changes of the general public in China from January 30 to February 3, 2020. Methods: Respondents were recruited via social media (WeChat) and completed an online questionnaire. We used the State-Trait Anxiety Inventory, Self-rating Depression Scale, and Symptom Checklist-90 to evaluate psychological status. We also investigated respondents’ behavior changes. Quantitative data were analyzed by t-tests or analysis of variance, and classified data were analyzed with chi-square tests. Results: In total, 608 valid questionnaires were obtained. More respondents had state anxiety than trait anxiety (15.8% vs 4.0%). Depression was found among 27.1% of respondents and 7.7% had psychological abnormalities. About 10.1% of respondents suffered from phobia. Our analysis of the relationship between subgroup characteristics and psychological status showed that age, gender, knowledge about COVID-19, degree of worry about epidemiological infection, and confidence about overcoming the outbreak significantly influenced psychological status. Around 93.3% of respondents avoided going to public places and almost all respondents reduced Spring Festival-related activities. -
RAMOS RIERA, I., COVID-19. Zugzwang Hacia Oriente
COVID-19: ZUGZWANG HACIA ORIENTE Ignacio Ramos Riera. Profesor de Relaciones Internacionales en la Universidad Pontificia Comillas ([email protected]) Research published in the issue n. 62 of the “Boletín Cátedra China”: https://www.catedrachina.com/single-post/2020/05/20/Covid-19-Zugzwang-Hacia-Oriente En ajedrez el Zugzwang (literalmente “coerción a mover”) es una situación ideal donde generalmente el rey enemigo es conducido a una casilla a la que no querría ir de forma que su situación estratégica empeora. Se trata de un arrinconamiento que se produce cuando le toca mover al contrincante, pero las piezas rivales no le permiten más que una cierta alternativa que suele dejarle peor de lo que estaba. En estos tiempos convulsos, diferentes líderes de países importantes del mundo occidental o anglosajón están levantando la voz con un movimiento incisivo de alfil a lo largo de la gran diagonal que llega hasta Oriente, más en concreto hasta China. Los gobiernos de EE. UU., Francia, Australia o Gran Bretaña han realizado últimamente declaraciones públicas poniendo en cuestión la credibilidad del gobierno de la RP China en la gestión y comunicación de la epidemia, no solo con respecto a sus fases primigenias, sino hasta el día de hoy. Confrontados con el vuelco radical de sus presupuestos nacionales, tienen premura por colocar a China en Zugzwang. Sin embargo, la legítima competitividad entre los viejos dominadores del tablero global y la resurgente superpotencia que tendrá lugar en la nueva era post-COVID-19, debería ir acompañada de algunas ganancias en la conciencia colectiva de lo que son movimientos precipitados que pueden malograr la partida. -
COVID-19 Vaccine Weekly Update
Ramona Whittington From: Roxana Cruz Sent: Tuesday, January 12, 2021 5:37 PM To: Medical Directors; catherine.threatt; Lindsay Lanagan; Myrta Garcia; Jennifer Mertz; [email protected] Cc: ClinicalTeam; Shelby Tracy; Jana Eubank; Daniel Diaz; Nancy Gilliam; Ramona Whittington; Missy Apodaca Subject: COVID-19 Vaccine Weekly Update Attachments: Interim+suggested+actions+for+COVID+variant+surveillance_1.05.2021.pdf; COVID-19-Surveillance- Worksheet-annotated-508+highlighted.pdf; 5-things-to-know_COVID Vaccine Msg.pdf; Lancet Article_6mo post COVID Consequences.pdf; Health-Center-Response-to-COVID-19-Infographic- January-1.pdf; COVIDVaccineAllocation-Week5.pdf Importance: High Dear Fellow Medical Directors, This is your weekly update for the COVID‐19 Vaccines, we have included the links and attachments which you may find useful for review and implementation at your health centers. We have also included resources for therapeutics for non‐ hospitalized high risk patients, post‐COVID care, educational opportunities, and messaging for your health center staff and patients. As of 1/12/2021: 39 Texas Health Centers (76 Clinic Sites) have been allocated a total of 15,500 doses to date Which includes the 1,000 doses allocated to 10 Texas health center sites during Week 5 (01/11/2021) 62 Health Centers are either “Approved” and/or “Pending Approval” 121 Approved Health Center sites That brings us to 9 health Centers with “Signatures pending” needing signatures from CMO or CEO (total of 14 clinic sites). I will reach out this week via e‐mail to see -
The Role of Immune System and Sterilization on the Covid-19 Spread Control
Sys Rev Pharm 2021;12(1):579-592 A multifaceted review journal in the field of pharmacy The Role of Immune System and Sterilization on the Covid-19 Spread Control *Hazim Saad Jabbar Al-Maliki1, Rana Adnan Fayez Al-jaberi 2, Abdul Amir H. Kadhum3, Moaed E. Al-Gazally3, Rahem Mahdy Rahem3, Sameer H. Abbood Al-Rekabi3 1Department of Basic Sciences, College of Dentistry, University of Basrah, Iraq. 2Department of Microbiology, College of Veterinary Medicine, University of Basrah, Iraq 3College of Medicine, University of Al-Ameed, Karbala, Iraq Hazim Saad Jabbar Al-Maliki, E-mail: [email protected], ORCID: htps://orcid.org/0000-0003-0779-2023 Rana Adnan Fayez Al-jaberi E-mail: [email protected] ORCID: htps://orcid.org/0000-0002-3119-3154 Abdul Amir H. Kadhum, E-mail: [email protected], ORCID: htps://orcid.org/000-0003-4074-9123 Moaed E. Al-Gazally, E-mail: [email protected], ORCID: htps://orcid.org/0000-0002-5325-5280 Rahem Mahdy Rahem, E-mail: [email protected] ABSTRACT In the early first months of 2020. The WHO declared that the COVID-19 is a Keywords: Immune system, sterilization, disinfectant, COVID-19 global pandemic. Which is spread rapidly across the majority of the continents all over the world. This dangerous virus infects the respiratory system. Leading Correspondence: to severe cases, to necrosis in the lung and difficulty in respiration pain and Hazim Saad Jabbar Al-Maliki defect in kidney. Some cases recovered from this disease and other led to Department of Basic Sciences, College of Dentistry, University of Basrah, Iraq. death. -
The Clinical Characteristics and Treatment Approaches of COVID-19: a Concise Review, Pharm Sci
The following manuscript was accepted for publication in Pharmaceutical Sciences. It is assigned to an issue after technical editing, formatting for publication and author proofing Citation: Eslamkhah S, Alizadeh N, Hajiasgharzadeh K, Eslamkhah M, Mokhtarzadeh A, Baradaran B. The clinical characteristics and treatment approaches of COVID-19: a concise review, Pharm Sci. 2021, doi: 10.34172/PS.2021.6 The clinical characteristics and treatment approaches of COVID-19: a concise review Running title: COVID-19 characteristics and treatment Sajjad Eslamkhah1≠, Nazila Alizadeh1≠, Khalil Hajiasgharzadeh1, Masoud Eslamkhah2, Ahad Mokhtarzadeh1, Behzad Baradaran1,3,4* 1Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. 2Islamic Azad University Central Tehran Branch, Tehran, Iran. 3Pharmaceutical Analysis Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. 4Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. ≠ These authors contributed equally to this work. * Corresponding author: Behzad Baradaran, PhD Immunology Research Center Tabriz University of Medical Sciences Daneshghah Ave, Tabriz, Iran. E-mail address: [email protected] 1 Abstract A series of cases of pneumonia occurred in China in late 2019. For this type of coronavirus, the WHO formally identified the condition as a coronavirus disease 2019 (COVID-19). They announced that this disease is the recent main concern of health problems in the world. Transfer of this novel coronavirus (nCoV) from human to human exists predominantly among family members, who have close contact with each other. This review article is provided based on the recent findings of COVID- 19, which were retrieved by searching PubMed, Google Scholar, Scopus, and Web of Science until December 2020. -
West Nile Virus Bibliography, 1965-2004 May Be Viewed As One Complete Publication File Below Or by Individual Sections at Westnilebib.Htm
NATIONAL AGRICULTURAL LIBRARY ARCHIVED FILE Archived files are provided for reference purposes only. This file was current when produced, but is no longer maintained and may now be outdated. Content may not appear in full or in its original format. All links external to the document have been deactivated. For additional information, see http://pubs.nal.usda.gov. West Nile Virus NOTE: West Nile Virus Bibliography, 1965-2004 may be viewed as one complete publication file below or by individual sections at westnilebib.htm United States Department of West Nile Virus Bibliography, 1965-2004 Agriculture February 2003, Updated December 2004 Agricultural West Nile Virus Fact Sheet Research Service National Gregg Goodman Laudie Baer* Agricultural Barbara Buchanan The College of Information Studies Library Jean Larson University of Maryland, College Park Animal Welfare Information Center U.S. Department of Agriculture Agricultural Research Service Animal Welfare National Agricultural Library Information 10301 Baltimore Avenue Center Beltsville, MD 20705-2351 Telephone: (301) 504-6212 Fax: (301) 504-7125 Contact us: http://awic.nal.usda.gov/contact-us Website: http://awic.nal.usda.gov *Updates for 2003 through May 2004 were completed as an independent study requirement for a Masters Degree in Information Management. Web Policies and Important Links Information on how to request materials that are included in the collection of the National Agricultural Library (NAL) may be found on the Collection Services Branch Website at http://www.nal.usda.gov/borrow-materials. Please read carefully as there are certain restrictions on media and document types. Bibliography 2004 / 2003 / 2002 / 2001 / 2000 / 1999 / 1998 / 1997 / 1996 / 1995 / 1994 / 1993 / 1992 / 1991 / 1990 / 1989 / 1988 / 1987 / 1986 / 1985 / 1984 / 1983 / 1982 / 1981 / 1980 / 1979 / 1978 / 1977 / 1976 / 1975 / 1974 / 1973 / 1972 / 1971 / 1970 / 1969 / 1968 / 1967 / 1966 / 1965 Introduction In 1999, an exotic disease emerged in the middle of New York City. -
Covid-19) Pandemia on the Number of Tourist Arrivals in Hong Kong: a Comparative Analysis with Figures of Last Five Years
MANAS Sosyal Araştırmalar Dergisi 2020 Cilt: 9 Sayı: 4 MANAS Journal of Social Studies 2020 Volume: 9 No: 4 ISSN: 1694-7215 Research Paper / Araştırma Makalesi Effects of Novel Coronavirus (Covid-19) Pandemia on the Number of Tourist Arrivals in Hong Kong: A Comparative Analysis with Figures of Last Five Years Halil AKMEŞE1 & Ali ILGAZ2 Abstract Recently, the whole world has faced a new type of coronavirus. The virus, called Covid-19, which was first seen in Wuhan, China and started to spread rapidly to other countries, has come to a halt all around the world due to its high spreading rate and being a deadly virus. In the face of the situation that has turned into a universal public health crisis, some countries have reduced their commercial relations with other countries and even international travel restrictions have been introduced in many countries. Since almost all countries close their borders and stop international travel, international tourism activities have also lost their dynamism. In this study, the first effects of the novel coronavirus on tourism were tried to be determined. For this purpose, the number of foreign tourists coming to Hong Kong from some countries and continents in January 2020 was compared with the data of January of the last five years with the help of graphics. As a result of the research, it has been determined that the number of foreign tourists visiting Hong Kong in January 2020 has decreased significantly compared to January of the last five years. In addition, when compared with the SARS virus seen in 2003, it was observed that the novel coronavirus had more negative effects on airway transportation and the number of passengers coming to Hong Kong. -
China Human Rights Report 2020》
臺灣民主基金會 Taiwan Foundation for Democracy 本出版品係由財團法人臺灣民主基金會負責出版。臺灣民主基金會是 一個獨立、非營利的機構,其宗旨在促進臺灣以及全球民主、人權的 研究與發展。臺灣民主基金會成立於二○○三年,是亞洲第一個國家 級民主基金會,未來基金會志在與其他民主國家合作,促進全球新一 波的民主化。 This is a publication of the Taiwan Foundation for Democracy (TFD). The TFD is an independent, non-profit foundation dedicated to the study and promotion of democracy and human rights in Taiwan and abroad. Founded in 2003, the TFD is the first democracy assistance foundation established in Asia. The Foundation is committed to the vision of working together with other democracies, to advance a new wave of democratization worldwide. 本報告由臺灣民主基金會負責出版,報告內容不代表本會意見。 版權所有,非經本會事先書面同意,不得翻印、轉載及翻譯。 This report has been published by the Taiwan Foundation for Democracy. Statements of fact or opinion appearing in this report do not imply endorsement by the publisher. All rights reserved. No portion of the contents may be reproduced in any form or by any means without prior written permission of the publisher. 臺灣民主基金會 Taiwan Foundation for Democracy 臺灣民主基金會 Taiwan Foundation for Democracy 《China Human Rights Report 2020》 Contents Foreword.................................................................................................... i Preface........................................................................................................ 1 Human Rights Dialogue and Confrontation between China and the World...................................................................................... 23 Political Rights ....................................................................................... -
Understanding Chinese Consumers: Growth Engine of the World Special Edition
China consumer report 2021 Understanding Chinese Consumers: Growth Engine of the World Special edition 2020 November 2020 China consumer report 2021 Understanding Chinese Consumers: Growth Engine of the World Special edition Chief editors: Daniel Zipser, Felix Poh Authors: Antonio Achille, Caleb Balloch, Lambert Bu, Cherry Chen, Guang Chen, Lucille Chen, Will Enger, Johnny Ho, Xin Huang, Daniel Hui, Dymfke Kuijpers, Nick Leung, Lavonda Li, Joanna Mak, Joe Ngai, Felix Poh, David Pountney, Alex Sawaya, Steve Saxon , Jeongmin Seong, Sha Sha, Kay Tu, Jonathan Woetzel, Chenan Xia, Lei Xu, Hai Ye, Jackey Yu, Stefano Zerbi, Cherie Zhang, Jia Zhou, Daniel Zipser Managing editors: Glenn Leibowitz, Lin Lin, Zhijuan Lu Project management: Johnny Ho, Kay Tu, Pauline Chen, Hao Xu, Chloe Chan Copyright © 2020 McKinsey & Company China consumer report 2021 Understanding Chinese Consumers: Growth Engine of the World Special edition 2 China consumer report 2021 Contents Foreword 5 China: Still the world’s growth engine after COVID-19 Revving the engine: The COVID-19 impact 8 Fast forward China: How COVID-19 is accelerating 5 key 10 trends shaping the Chinese economy How COVID-19 has changed Chinese consumption 34 How Chinese consumers are changing shopping habits in 44 response to COVID-19 Winning the future of grocery retail in China 56 What can other countries learn from China’s travel recovery 68 path? A perspective on luxury goods companies during and after 80 coronavirus The driver’s seat: Leadership perspectives 88 Leading through a crisis: How McDonald’s -
Censorship, Disinformation, and Propaganda
NLP4IF 2021 NLP for Internet Freedom: Censorship, Disinformation, and Propaganda Proceedings of the Fourth Workshop June 6, 2021 Copyright of each paper stays with the respective authors (or their employers). Order copies of this and other ACL proceedings from: Association for Computational Linguistics (ACL) 209 N. Eighth Street Stroudsburg, PA 18360 USA Tel: +1-570-476-8006 Fax: +1-570-476-0860 [email protected] ISBN 978-1-954085-26-8 ii Preface Welcome to the fourth edition of the Workshop on NLP for Internet Freedom: Censorship, Disinformation, and Propaganda. This is the second time we are running the workshop virtually, due to the COVID-19 pandemic. The pandemic has had a profound effect on the lives of people around the globe and, as much cliché as it may sound, we are all in this together. COVID-19 is the first pandemic in history in which technology and social media are being used on a massive scale to help people stay safe, informed, productive and connected. At the same time, the same technology that we rely on to keep us connected and informed is enabling and amplifying an infodemic that continues to undermine the global response and is detrimental to the efforts to control the pandemic. In the context of the pandemic, we define an infodemic as deliberate attempts to disseminate false information to undermine the public health response and to advance alternative agendas promoted by groups or individuals. We also realize that there is a vicious cycle: the more content is produced, the more misinformation and disinformation expand. The Internet is overloaded with false cures, such as drinking bleach or colloidal silver, conspiracy theories about the virus’ origin, false claims that the COVID-19 vaccine will change patient’s DNA or will serve to implant in us a tracking microchip, misinformation about methods such masks and social distancing, myths about the dangers and the real-world consequences of COVID- 19. -
VOlume 20 • ISsue 8 • MAy 1, 2020
VOLUME 20 • ISSUE 8 • MAY 1, 2020 IN THIS ISSUE: Beijing Promotes “National Security” Measures to Seek Tighter Control Over Hong Kong By John Dotson………………………………………………………pp. 2-7 “State Companies Advance and Private Firms Retreat” in China’s Bid to Resuscitate the Economy By Willy Lam…………………………………………………………..pp. 8-11 Global Supply Chains, Economic Decoupling, and U.S.-China Relations Part 2: The View from the People’s Republic of China By Sagatom Saha and Ashley Feng………………………………...pp. 12-17 Chinese Survey Vessel Incident Puts Malaysia’s South China Sea Approach Under Scrutiny By Prashanth Parameswaran………………………………………..pp. 18-23 Examining China’s Organ Transplantation System: The Nexus of Security, Medicine, and Predation Part 1: The Growth of China's Transplantation System Since 2000 By Matthew P. Robertson…………………………………………….pp. 24-29 1 ChinaBrief • Volume 20 • Issue 8 • May 1, 2020 Beijing Promotes “National Security” Measures to Seek Tighter Control Over Hong Kong By John Dotson Introduction: Beijing’s Personnel Appointments and Advocacy of “Patriotic Education” Luo Huining (骆惠宁) was appointed in January 2020 as Director of the Liaison Office of the Central People's Government in the Hong Kong Special Administrative Region (中央人民政府驻香港特别行政区联络办公 室, Zhongyang Renmin Zhengfu Zhu Xianggang Tebie Xingzhengqu Lianluo Bangongshi) (hereafter “Central Liaison Office”), thereby placing him in charge of Beijing’s on-scene office for managing Hong Kong affairs. In taking up this role, Luo succeeded Wang Zhimin (王志民), who was likely replaced as a sign of Beijing’s displeasure with the failure to more effectively rein in anti-establishment protests throughout the second half of 2019 (HKFP, January 20).