August 13, 2013 u vol. 110 u no. 33 u 13229–13692

Cover image: Pictured is a pectinarid polychaete, a type of marine worm that feeds on deep sea sediment. Erik A. Sperling et al. surveyed the feeding strategies of various polychaetes found in low-oxygen regions and found that carnivorous organisms decrease in abundance with decreasing oxygen levels. The findings help to explain the origin of animal food webs in low-oxygen Precambrian oceans, and may help to predict future changes in ocean ecology associated with the expansion of low-oxygen regions. See the article by Sperling et al. on pages 13446–13451. Image courtesy of Christina A. Frieder. From the Cover

13446 Oxygen levels and feeding ecology 13283 Prebiotic chemistry at hydrothermal vents 13300 Linking two branches of mathematical logic 13328 Evolution of social monogamy 13672 Sardine and anchovy fluctuation patterns

E3051 Why climate change will not dramatically decrease Contents viticultural suitability in main wine-producing areas by 2050 Cornelis van Leeuwen, Hans R. Schultz, Iñaki Garcia de Cortazar-Atauri, Eric Duchêne, Nathalie Ollat, Philippe Pieri, Benjamin Bois, Jean-Pascal Goutouly, Hervé Quénol, THIS WEEK IN PNAS Jean-Marc Touzard, Aureliano C. Malheiro, Luigi Bavaresco, and Serge Delrot 13229 In This Issue E3053 Reply to van Leeuwen et al.: Planning for agricultural adaptation to climate change and its consequences for conservation Lee Hannah, Patrick R. Roehrdanz, Makihiko Ikegami, LETTERS (ONLINE ONLY) Anderson V. Shepard, M. Rebecca Shaw, Gary Tabor, Lu Zhi, Pablo A. Marquet, and Robert J. Hijmans

E3047 Toba supereruption: Age and impact on East African ecosystems NEWS FEATURE Richard G. Roberts, Michael Storey, and Michael Haslam 13231 Spherical nucleic acids: A whole new ball game E3048 Reply to Roberts et al.: A subdecadal record of Sarah C. P. Williams paleoclimate around the Youngest Toba Tuff in Lake Malawi Christine S. Lane, Ben T. Chorn, RETROSPECTIVE and Thomas C. Johnson

E3049 Interpretative problems with chimpanzee 13234 Christian de Duve: Explorer of the cell who discovered ultimatum game new organelles by using a centrifuge Joseph Henrich and Joan B. Silk David D. Sabatini and Milton Adesnik

E3050 Reply to Henrich and Silk: Toward a unified explanation for apes and humans COMMENTARIES Darby Proctor, Rebecca A. Williamson, Frans B. M. de Waal, and Sarah F. Brosnan 13236 Mapping metabolism onto the prebiotic organic chemistry of hydrothermal vents Rogier Braakman Free online through the PNAS open access option. See companion article on page 13283

PNAS u August 13, 2013 u vol. 110 u no. 33 u iii–viii Downloaded by guest on October 1, 2021 13238 Model theory and the cardinal numbers p and t IMMUNOLOGY Justin Tatch Moore E3109 Interferon-induced RIP1/RIP3-mediated necrosis requires See companion article on page 13300 PKR and is licensed by FADD and caspases 13240 Modeling sardine and anchovy low-frequency variability Roshan J. Thapa, Shoko Nogusa, Peirong Chen, Jenny L. Salvador E. Lluch-Cota Maki, Anthony Lerro, Mark Andrake, Glenn F. Rall, See companion article on page 13672 Alexei Degterev, and Siddharth Balachandran E3119 MAIT cells are critical for optimal mucosal immune responses during in vivo pulmonary bacterial infection Anda Meierovics, Wei-Jen Chua Yankelevich, and Siobhán C. Cowley PNAS PLUS

13242 SIGNIFICANCE STATEMENTS MICROBIOLOGY

PHYSICAL SCIENCES E3129 Metagenomic natural product discovery in lichen provides evidence for a family of biosynthetic pathways ENGINEERING in diverse symbioses Annette Kampa, Andrey N. Gagunashvili, Tobias A. M. E3054 Effect of cholesterol nanodomains on monolayer Gulder, Brandon I. Morinaka, Cristina Daolio, Markus morphology and dynamics Godejohann, Vivian P. W. Miao, Jörn Piel, KyuHan Kim, Siyoung Q. Choi, Zachary A. Zell, and Ólafur S. Andrésson Todd M. Squires, and Joseph A. Zasadzinski

BIOLOGICAL SCIENCES NEUROSCIENCE E3138 Heparan sulfate proteoglycans mediate internalization BIOCHEMISTRY and propagation of specific proteopathic seeds E3061 Microsatellite-encoded domain in rodent Sry functions Brandon B. Holmes, Sarah L. DeVos, Najla Kfoury, Mei Li, as a genetic capacitor to enable the rapid evolution of Rachel Jacks, Kiran Yanamandra, Mohand O. Ouidja, biological novelty Frances M. Brodsky, Jayne Marasa, Devika P. Bagchi, Paul T. Yen-Shan Chen, Joseph D. Racca, Paul W. Sequeira, Kotzbauer, Timothy M. Miller, Dulce Papy-Garcia, Nelson B. Phillips, and Michael A. Weiss and Marc I. Diamond E3071 Insight into mechanisms of 3′-5′ exonuclease activity and removal of bulky 8,5′-cyclopurine adducts by apurinic/apyrimidinic endonucleases Abdelghani Mazouzi, Armelle Vigouroux, Bulat Aikeshev, PHYSICAL SCIENCES Philip J. Brooks, Murat K. Saparbaev, Solange Morera, and Alexander A. Ishchenko APPLIED MATHEMATICS E3081 Mod5 protein binds to tRNA gene complexes and affects 13422 Increased transmissibility explains the third wave of local transcriptional silencing infection by the 2009 H1N1 pandemic virus in England Matthew Pratt-Hyatt, Dave A. Pai, Rebecca A. Haeusler, Ilaria Dorigatti, Simon Cauchemez, and Neil M. Ferguson Glenn G. Wozniak, Paul D. Good, Erin L. Miller, Ian X. McLeod, John R. Yates III, Anita K. Hopper, and David R. Engelke APPLIED PHYSICAL SCIENCES E3090 Prereplicative repair of oxidized bases in the human 13244 COPI buds 60-nm lipid droplets from reconstituted – – genome is mediated by NEIL1 DNA glycosylase together water phospholipid triacylglyceride interfaces, with replication proteins suggesting a tension clamp function Muralidhar L. Hegde, Pavana M. Hegde, Larry J. Bellot, Abdou Rachid Thiam, Bruno Antonny, Jing Wang, Jérôme fl Santi M. Mandal, Tapas K. Hazra, Guo-Min Li, Istvan Delacotte, Florian Wil ing, Tobias C. Walther, Rainer Beck, Boldogh, Alan E. Tomkinson, and Sankar Mitra James E. Rothman, and Frédéric Pincet 13250 Hyperuniformity in amorphous silicon based on the measurement of the infinite-wavelength limit of the BIOPHYSICS AND COMPUTATIONAL BIOLOGY structure factor E3054 Effect of cholesterol nanodomains on monolayer Ruobing Xie, Gabrielle G. Long, Steven J. Weigand, Simon C. morphology and dynamics Moss, Tobi Carvalho, Sjoerd Roorda, Miroslav Hejna, KyuHan Kim, Siyoung Q. Choi, Zachary A. Zell, Salvatore Torquato, and Paul J. Steinhardt Todd M. Squires, and Joseph A. Zasadzinski 13255 Open-atmosphere sustenance of highly volatile attoliter-size droplets on surfaces CELL BIOLOGY Patrick Galliker, Julian Schneider, Lukas Rüthemann, and Dimos Poulikakos E3100 Protective effect of mitochondria-targeted antioxidants in an acute bacterial infection 13261 High thermoelectric performance by resonant dopant Egor Y. Plotnikov, Maria A. Morosanova, Irina B. Pevzner, indium in nanostructured SnTe Ljubava D. Zorova, Vasily N. Manskikh, Natalya V. Pulkova, Qian Zhang, Bolin Liao, Yucheng Lan, Kevin Lukas, Weishu Svetlana I. Galkina, Vladimir P. Skulachev, Liu, Keivan Esfarjani, Cyril Opeil, David Broido, Gang Chen, and Dmitry B. Zorov and Zhifeng Ren

iv u www.pnas.org Downloaded by guest on October 1, 2021 ASTRONOMY 13312 Lattice effects on ferromagnetism in 13267 Seismic constraints on rotation of Sun-like star and mass perovskite ruthenates of exoplanet J.-G. Cheng, J.-S. Zhou, and John B. Goodenough Laurent Gizon, Jérome Ballot, Eric Michel, Thorsten Stahn, Gérard Vauclair, Hans Bruntt, Pierre-Olivier Quirion, STATISTICS Othman Benomar, Sylvie Vauclair, Thierry Appourchaux, Michel Auvergne, Annie Baglin, Caroline Barban, Fréderic 13316 On the origins of hierarchy in complex networks Baudin, Michaël Bazot, Tiago Campante, Claude Catala, Bernat Corominas-Murtra, Joaquín Goñi, Ricard V. Solé, William Chaplin, Orlagh Creevey, Sébastien Deheuvels, Noël and Carlos Rodríguez-Caso Dolez, Yvonne Elsworth, Rafael García, Patrick Gaulme, Stéphane Mathis, Savita Mathur, Benoît Mosser, Clara Régulo, Ian Roxburgh, David Salabert, Réza Samadi, Kumiko Sato, Graham Verner, Shravan Hanasoge, SOCIAL SCIENCES and Katepalli R. Sreenivasan

ANTHROPOLOGY CHEMISTRY 13440 Reproductive aging patterns in primates reveal that 13272 Nucleobases bind to and stabilize aggregates of humans are distinct a prebiotic amphiphile, providing a viable mechanism Susan C. Alberts, Jeanne Altmann, Diane K. Brockman, for the emergence of protocells Marina Cords, Linda M. Fedigan, Anne Pusey, Tara S. Roy A. Black, Matthew C. Blosser, Benjamin L. Stottrup, Stoinski, Karen B. Strier, William F. Morris, Ravi Tavakley, David W. Deamer, and Sarah L. Keller and Anne M. Bronikowski 13277 How hydrophobic drying forces impact the kinetics of molecular recognition Jagannath Mondal, Joseph A. Morrone, and B. J. Berne BIOLOGICAL SCIENCES 13283 Reactivity landscape of pyruvate under simulated hydrothermal vent conditions Yehor Novikov and Shelley D. Copley ANTHROPOLOGY See Commentary on page 13236 13322 Archaeological, radiological, and biological evidence offer insight into Inca child sacrifice EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES Andrew S. Wilson, Emma L. Brown, Chiara Villa, Niels 13446 Oxygen, ecology, and the Cambrian radiation of animals Lynnerup, Andrew Healey, Maria Constanza Ceruti, Johan Erik A. Sperling, Christina A. Frieder, Akkur V. Raman, Reinhard, Carlos H. Previgliano, Facundo Arias Araoz, fi Peter R. Girguis, Lisa A. Levin, and Andrew H. Knoll Jose na Gonzalez Diez, and Timothy Taylor 13328 Male infanticide leads to social monogamy in primates ENGINEERING Christopher Opie, Quentin D. Atkinson, Robin I. M. Dunbar, and Susanne Shultz 13289 Reducing deformation anisotropy to achieve ultrahigh strength and ductility in Mg at the nanoscale Qian Yu, Liang Qi, Raja K. Mishra, Ju Li, BIOCHEMISTRY and Andrew M. Minor 13244 COPI buds 60-nm lipid droplets from reconstituted 13356 Lipid bilayer and cytoskeletal interactions in a red water–phospholipid–triacylglyceride interfaces, blood cell suggesting a tension clamp function Zhangli Peng, Xuejin Li, Igor V. Pivkin, Ming Dao, Abdou Rachid Thiam, Bruno Antonny, Jing Wang, Jérôme George E. Karniadakis, and Subra Suresh Delacotte, Florian Wilfling, Tobias C. Walther, Rainer Beck, James E. Rothman, and Frédéric Pincet ENVIRONMENTAL SCIENCES 13272 Nucleobases bind to and stabilize aggregates of 13294 Unexpectedly high indoor hydroxyl radical a prebiotic amphiphile, providing a viable mechanism concentrations associated with nitrous acid for the emergence of protocells Elena Gómez Alvarez, Damien Amedro, Charbel Afif, Sasho Roy A. Black, Matthew C. Blosser, Benjamin L. Stottrup, Gligorovski, Coralie Schoemacker, Christa Fittschen, Ravi Tavakley, David W. Deamer, and Sarah L. Keller Jean-Francois Doussin, and Henri Wortham 13333 Identification of the molecular attributes required for aminoglycoside activity against Leishmania MATHEMATICS Moran Shalev, Jiro Kondo, Dmitry Kopelyanskiy, 13300 General topology meets model theory, on p and t Charles L. Jaffe, Noam Adir, and Timor Baasov Maryanthe Malliaris and Saharon Shelah 13339 Human eIF4E promotes mRNA restructuring by See Commentary on page 13238 stimulating eIF4A helicase activity Kateryna Feoktistova, Enkhee Tuvshintogs, Angelie Do, PHYSICS and Christopher S. Fraser 13306 Random network peristalsis in Physarum polycephalum 13345 Structural basis of Vps33A recruitment to the human organizes fluid flows across an individual HOPS complex by Vps16 Karen Alim, Gabriel Amselem, François Peaudecerf, Stephen C. Graham, Lena Wartosch, Sally R. Gray, Edward J. Michael P. Brenner, and Anne Pringle Scourfield, Janet E. Deane, J. Paul Luzio, and David J. Owen

PNAS u August 13, 2013 u vol. 110 u no. 33 u v Downloaded by guest on October 1, 2021 13351 Relocating the active-site lysine in rhodopsin and DEVELOPMENTAL BIOLOGY implications for evolution of retinylidene proteins 13410 MicroRNA-126–mediated control of cell fate in B-cell Erin L. Devine, Daniel D. Oprian, and Douglas L. Theobald myeloid progenitors as a potential alternative to transcriptional factors Kazuki Okuyama, Tomokatsu Ikawa, Bernhard Gentner, BIOPHYSICS AND COMPUTATIONAL BIOLOGY Katsuto Hozumi, Ratanakanit Harnprasopwat, Jun Lu, Riu 13277 How hydrophobic drying forces impact the kinetics of Yamashita, Daon Ha, Takae Toyoshima, Bidisha Chanda, molecular recognition Toyotaka Kawamata, Kazuaki Yokoyama, Shusheng Wang, Jagannath Mondal, Joseph A. Morrone, and B. J. Berne Kiyoshi Ando, Harvey F. Lodish, Arinobu Tojo, Hiroshi Kawamoto, and Ai Kotani 13306 Random network peristalsis in Physarum polycephalum organizes fluid flows across an individual 13416 Translational profiling of cardiomyocytes identifies an Karen Alim, Gabriel Amselem, François Peaudecerf, early Jak1/Stat3 injury response required for zebrafish Michael P. Brenner, and Anne Pringle heart regeneration Yi Fang, Vikas Gupta, Ravi Karra, Jennifer E. Holdway, 13356 Lipid bilayer and cytoskeletal interactions in a red Kazu Kikuchi, and Kenneth D. Poss blood cell Zhangli Peng, Xuejin Li, Igor V. Pivkin, Ming Dao, George E. Karniadakis, and Subra Suresh ECOLOGY 13362 Characterization of an early-stage fusion intermediate 13422 Increased transmissibility explains the third wave of of Sindbis virus using cryoelectron microscopy infection by the 2009 H1N1 pandemic virus in England Sheng Cao and Wei Zhang Ilaria Dorigatti, Simon Cauchemez, and Neil M. Ferguson 13368 Coarse-grained, foldable, physical model of the 13428 Agent-based Bayesian approach to monitoring the polypeptide chain progress of invasive species eradication programs Promita Chakraborty and Ronald N. Zuckermann Jonathan M. Keith and Daniel Spring 13374 Structural and dynamic studies of the transcription 13434 Community-level phenological response to factor ERG reveal DNA binding is climate change allosterically autoinhibited Otso Ovaskainen, Svetlana Skorokhodova, Marina Yakovleva, Michael C. Regan, Peter S. Horanyi, Edward E. Alexander Sukhov, Anatoliy Kutenkov, Nadezhda Pryor, Jr., Jessica L. Sarver, David S. Cafiso, Kutenkova, Anatoliy Shcherbakov, Evegeniy Meyke, and John H. Bushweller and Maria del Mar Delgado 13380 Membrane extraction of Rab proteins by GDP EVOLUTION dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy 13316 On the origins of hierarchy in complex networks Konstantin Gavriljuk, Aymelt Itzen, Roger S. Goody, Bernat Corominas-Murtra, Joaquín Goñi, Ricard V. Solé, Klaus Gerwert, and Carsten Kötting and Carlos Rodríguez-Caso 13386 Structures of P-glycoprotein reveal its conformational 13440 Reproductive aging patterns in primates reveal that flexibility and an epitope on the nucleotide-binding humans are distinct domain Susan C. Alberts, Jeanne Altmann, Diane K. Brockman, Andrew B. Ward, Paul Szewczyk, Vinciane Grimard, Marina Cords, Linda M. Fedigan, Anne Pusey, Tara S. Chang-Wook Lee, Lorena Martinez, Rupak Doshi, Stoinski, Karen B. Strier, William F. Morris, Alexandra Caya, Mark Villaluz, Els Pardon, Cristina and Anne M. Bronikowski Cregger, Douglas J. Swartz, Pierre Guy Falson, 13446 Oxygen, ecology, and the Cambrian radiation of animals Ina L. Urbatsch, Cedric Govaerts, Jan Steyaert, Erik A. Sperling, Christina A. Frieder, Akkur V. Raman, and Geoffrey Chang Peter R. Girguis, Lisa A. Levin, and Andrew H. Knoll 13392 Conformations of intrinsically disordered proteins are 13452 Rapid shifts in dispersal behavior on an expanding influenced by linear sequence distributions of oppositely range edge charged residues Tom Lindström, Gregory P. Brown, Scott A. Sisson, Rahul K. Das and Rohit V. Pappu Benjamin L. Phillips, and Richard Shine

CELL BIOLOGY GENETICS 13398 Selective activation of oxidized PTP1B by the thioredoxin 13457 Rates and patterns of great ape retrotransposition system modulates PDGF-β receptor tyrosine Fereydoun Hormozdiari, Miriam K. Konkel, Javier kinase signaling Prado-Martinez, Giorgia Chiatante, Irene Hernando Herraez, Markus Dagnell, Jeroen Frijhoff, Irina Pader, Martin Jerilyn A. Walker, Benjamin Nelson, Can Alkan, Peter H. Augsten, Benoit Boivin, Jianqiang Xu, Pankaj K. Mandal, Sudmant, John Huddleston, Claudia R. Catacchio, Arthur Ko, Nicholas K. Tonks, Carina Hellberg, Marcus Conrad, Maika Malig, Carl Baker, Great Ape Genome Project, Tomas Elias S. J. Arnér, and Arne Östman Marques-Bonet, Mario Ventura, Mark A. Batzer, and Evan E. Eichler 13404 Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by 13463 Genetic measurement of memory B-cell recall using phosphorylating Sororin antibody repertoire sequencing Tomoko Nishiyama, Martina M. Sykora, Pim J. Huis in ’t Christopher Vollmers, Rene V. Sit, Joshua A. Weinstein, Veld, Karl Mechtler, and Jan-Michael Peters Cornelia L. Dekker, and Stephen R. Quake

vi u www.pnas.org Downloaded by guest on October 1, 2021 13469 Pinpointing genes underlying the quantitative trait loci 13528 Epoxyeicosanoids promote organ and for root-knot nematode resistance in palaeopolyploid tissue regeneration soybean by whole genome resequencing Dipak Panigrahy, Brian T. Kalish, Sui Huang, Diane R. Xiangyang Xu, Liang Zeng, Ye Tao, Tri Vuong, Jinrong Wan, Bielenberg, Hau D. Le, Jun Yang, Matthew L. Edin, Craig R. Roger Boerma, Jim Noe, Zenglu Li, Steve Finnerty, Lee, Ofra Benny, Dayna K. Mudge, Catherine E. Butterfield, Safiullah M. Pathan, J. Grover Shannon, Akiko Mammoto, Tadanori Mammoto, Bora Inceoglu, and Henry T. Nguyen Roger L. Jenkins, Mary A. Simpson, Tomoshige Akino, Fred B. Lih, Kenneth B. Tomer, Donald E. Ingber, Bruce D. 13475 Break-induced replication occurs by conservative Hammock, John R. Falck, Vijaya L. Manthati, Arja DNA synthesis Kaipainen, Patricia A. D’Amore, Mark Puder, Darryl C. Roberto A. Donnianni and Lorraine S. Symington Zeldin, and Mark W. Kieran 13481 Whole-genome sequencing identifies a recurrent 13534 Insulin-dependent diabetes induced by pancreatic beta functional synonymous mutation in melanoma cell expression of IL-15 and IL-15Rα Jared J. Gartner, Stephen C. J. Parker, Todd D. Prickett, Jing Chen, Lionel Feigenbaum, Parirokh Awasthi, Donna O. Ken Dutton-Regester, Michael L. Stitzel, Jimmy C. Lin, Butcher, Miriam R. Anver, Yelena G. Golubeva, Richard Sean Davis, Vijaya L. Simhadri, Sujata Jha, Nobuko Bamford, Xiaojie Zhang, Mark B. St. Claire, Craig J. Katagiri, Valer Gotea, Jamie K. Teer, Xiaomu Wei, Thomas, Valentina Discepolo, Bana Jabri, Mario A. Morken, Umesh K. Bhanot, NISC Comparative and Thomas A. Waldmann Sequencing Program, Guo Chen, Laura L. Elnitski, Michael A. Davies, Jeffrey E. Gershenwald, Hannah Carter, 13540 Bispecific antibodies directed to CD4 domain 2 and HIV Rachel Karchin, William Robinson, Steven Robinson, envelope exhibit exceptional breadth and picomolar Steven A. Rosenberg, Francis S. Collins, Giovanni Parmigiani, potency against HIV-1 Anton A. Komar, Chava Kimchi-Sarfaty, Nicholas K. Craig S. Pace, Ruijiang Song, Christina Ochsenbauer, Hayward, Elliott H. Margulies, and Yardena Samuels Chasity D. Andrews, David Franco, Jian Yu, Deena A. Oren, Michael S. Seaman, and David D. Ho

IMMUNOLOGY 13546 SIRT2 directs the replication stress response through CDK9 deacetylation fl 13487 Acute in ammation primes myeloid effector cells for Hui Zhang, Seong-Hoon Park, Brooke G. Pantazides, fl anti-in ammatory STAT6 signaling Oleksandra Karpiuk, Matthew D. Warren, Claire W. Hardy, Fredrik Wermeling, Robert M. Anthony, Frank Brombacher, Duc M. Duong, So-Jeong Park, Hyun-Seok Kim, Athanassios and Jeffrey V. Ravetch Vassilopoulos, Nicholas T. Seyfried, Steven A. Johnsen, 13492 HLA targeting efficiency correlates with human T-cell David Gius, and David S. Yu fl response magnitude and with mortality from in uenza 13552 Targeting proximal tubule mitochondrial dysfunction A infection attenuates the renal disease of methylmalonic acidemia Tomer Hertz, Christine M. Oshansky, Philippa L. Irini Manoli, Justin R. Sysol, Lingli Li, Pascal Houillier, Roddam, John P. DeVincenzo, Miguela A. Caniza, Caterina Garone, Cindy Wang, Patricia M. Zerfas, Kristina Nebojsa Jojic, Simon Mallal, Elizabeth Phillips, Cusmano-Ozog, Sarah Young, Niraj S. Trivedi, Jun Cheng, Ian James, M. Elizabeth Halloran, Paul G. Thomas, Jennifer L. Sloan, Randy J. Chandler, Mones Abu-Asab, and Lawrence Corey Maria Tsokos, Abdel G. Elkahloun, Seymour Rosen, 13498 Virtual memory CD8 T cells display unique Gregory M. Enns, Gerard T. Berry, Victoria Hoffmann, functional properties Salvatore DiMauro, Jurgen Schnermann, June-Yong Lee, Sara E. Hamilton, Adovi D. Akue, and Charles P. Venditti Kristin A. Hogquist, and Stephen C. Jameson 13558 BRCA1 promotes the ubiquitination of PCNA and 13504 Structural basis for the stabilization of the complement recruitment of translesion polymerases in response to alternative pathway C3 convertase by properdin replication blockade Martín Alcorlo, Agustín Tortajada, Santiago Fen Tian, Shilpy Sharma, Jianqiu Zou, Shiaw-Yih Lin, Rodríguez de Córdoba, and Oscar Llorca Bin Wang, Khosrow Rezvani, Hongmin Wang, Jeffrey D. Parvin, Thomas Ludwig, Christine E. Canman, and Dong Zhang

MEDICAL SCIENCES 13564 Multiple antigen-presenting system (MAPS) to induce 13510 Role of lysine methylation of NF-κB in differential comprehensive B- and T-cell immunity gene regulation Fan Zhang, Ying-Jie Lu, and Richard Malley Tao Lu, Maojing Yang, De-Bin Huang, Han Wei, Gulcin H. 13570 Reexpression of pyruvate kinase M2 in type 1 myofibers Ozer, Gourisankar Ghosh, and George R. Stark correlates with altered glucose metabolism in 13516 PRMT5 dimethylates R30 of the p65 subunit to myotonic dystrophy activate NF-κB Zhihua Gao and Thomas A. Cooper Han Wei, Benlian Wang, Masaru Miyagi, Yun She, 13576 Acute myeloid leukemia does not deplete normal Banu Gopalan, De-Bin Huang, Gourisankar Ghosh, hematopoietic stem cells but induces cytopenias by George R. Stark, and Tao Lu impeding their differentiation 13522 RARα-PLZF oncogene inhibits C/EBPα function in Farideh Miraki-Moud, Fernando Anjos-Afonso, Katharine A. myeloid cells Hodby, Emmanuel Griessinger, Guglielmo Rosignoli, Debra Nathalie Girard, Mathieu Tremblay, Magali Humbert, Benoît Lillington, Li Jia, Jeff K. Davies, Jamie Cavenagh, Matthew Grondin, André Haman, Jean Labrecque, Bing Chen, Zhu Smith, Heather Oakervee, Samir Agrawal, John G. Gribben, Chen, Sai-Juan Chen, and Trang Hoang Dominique Bonnet, and David C. Taussig

PNAS u August 13, 2013 u vol. 110 u no. 33 u vii Downloaded by guest on October 1, 2021 MICROBIOLOGY PLANT BIOLOGY 13582 Metabolic niche of a prominent sulfate-reducing human 13660 Loss of function of cinnamyl alcohol dehydrogenase 1 gut bacterium leads to unconventional lignin and a temperature-sensitive Federico E. Rey, Mark D. Gonzalez, Jiye Cheng, Meng Wu, growth defect in Medicago truncatula Philip P. Ahern, and Jeffrey I. Gordon Qiao Zhao, Yuki Tobimatsu, Rui Zhou, Sivakumar Pattathil, Lina Gallego-Giraldo, Chunxiang Fu, Lisa A. Jackson, 13588 Induction of IL-17 and nonclassical T-cell activation by Michael G. Hahn, Hoon Kim, Fang Chen, John Ralph, HIV-Tat protein and Richard A. Dixon Tory P. Johnson, Karan Patel, Kory R. Johnson, Dragan Maric, Peter A. Calabresi, Rodrigo Hasbun, and Avindra Nath 13666 Phase-resetting mechanism of the circadian clock in Chlamydomonas reinhardtii fi fi 13594 Chemical screening identi es lastatin, a small molecule Yoshimi Niwa, Takuya Matsuo, Kiyoshi Onai, Daisaku Kato, inhibitor of Candida albicans adhesion, morphogenesis, Makoto Tachikawa, and Masahiro Ishiura and pathogenesis Ahmed Fazly, Charu Jain, Amie C. Dehner, Luca Issi, POPULATION BIOLOGY Elizabeth A. Lilly, Akbar Ali, Hong Cao, Paul L. Fidel, Jr., fi fl Reeta P. Rao, and Paul D. Kaufman 13672 Climate, shing, and uctuations of sardine and anchovy in the California Current 13600 BslA is a self-assembling bacterial hydrophobin that Martin Lindegren, David M. Checkley, Jr., Tristan Rouyer, coats the Bacillus subtilis biofilm Alec D. MacCall, and Nils Chr. Stenseth Laura Hobley, Adam Ostrowski, Francesco V. Rao, Keith M. See Commentary on page 13240 Bromley, Michael Porter, Alan R. Prescott, Cait E. MacPhee, Daan M. F. van Aalten, and Nicola R. Stanley-Wall PSYCHOLOGICAL AND COGNITIVE SCIENCES 13606 Catalytic domain of plasmid pAD1 relaxase TraX defines 13678 An integrated reweighting theory of perceptual learning a group of relaxases related to restriction endonucleases Barbara Anne Dosher, Pamela Jeter, Jiajuan Liu, María Victoria Francia, Don B. Clewell, Fernando and Zhong-Lin Lu de la Cruz, and Gabriel Moncalián 13684 A functional genomic perspective on human well-being NEUROSCIENCE Barbara L. Fredrickson, Karen M. Grewen, Kimberly A. Coffey, Sara B. Algoe, Ann M. Firestine, Jesusa M. G. 13612 Sound response mediated by the TRP channels NOMPC, Arevalo, Jeffrey Ma, and Steven W. Cole NANCHUNG, and INACTIVE in chordotonal organs of Drosophila larvae Wei Zhang, Zhiqiang Yan, Lily Yeh Jan, and Yuh Nung Jan CORRECTIONS 13618 Multibranch activity in basal and tuft dendrites during firing of layer 5 cortical neurons in vivo Daniel N. Hill, Zsuzsanna Varga, Hongbo Jia, Bert Sakmann, STATISTICS and Arthur Konnerth 13691 Using distance correlation and SS-ANOVA to assess associations of familial relationships, lifestyle factors, 13624 Speed-invariant encoding of looming object distance diseases, and mortality requires power law spike rate adaptation Jing Kong, Barbara E. K. Klein, Ronald Klein, Kristine E. Lee, Stephen E. Clarke, Richard Naud, André Longtin, and Grace Wahba and Leonard Maler

13630 Brain–computer interfaces increase whole-brain signal MEDICAL SCIENCES to noise 13690 NF-κB inhibits osteogenic differentiation of mesenchymal T. Dorina Papageorgiou, Jonathan M. Lisinski, Monica A. stem cells by promoting β-catenin degradation McHenry, Jason P. White, and Stephen M. LaConte Jia Chang, Fei Liu, Min Lee, Benjamin Wu, Kang Ting, 13636 Poststimulus undershoots in cerebral blood flow and Janette N. Zara, Chia Soo, Khalid Al Hezaimi, Weiping Zou, BOLD fMRI responses are modulated by poststimulus Xiaohong Chen, David J. Mooney, and Cun-Yu Wang neuronal activity Karen J. Mullinger, Stephen D. Mayhew, Andrew P. Bagshaw, NEUROSCIENCE Richard Bowtell, and Susan T. Francis 13691 Aβ induces astrocytic glutamate release, extrasynaptic 13642 Energetic cost of brain functional connectivity NMDA receptor activation, and synaptic loss Dardo Tomasi, Gene-Jack Wang, and Nora D. Volkow Maria Talantova, Sara Sanz-Blasco, Xiaofei Zhang, Peng Xia, Mohd Waseem Akhtar, Shu-ichi Okamoto, Gustavo 13648 Neuronal prostaglandin E2 receptor subtype EP3 Dziewczapolski, Tomohiro Nakamura, Gang Cao, Alexander E. mediates antinociception during inflammation Pratt, Yeon-Joo Kang, Shichun Tu, Elena Molokanova, Gabriel Natura, Karl-Jürgen Bär, Annett Eitner, Michael K. Scott R. McKercher, Samuel Andrew Hires, Hagit Sason, Boettger, Frank Richter, Susanne Hensellek, Andrea David G. Stouffer, Matthew W. Buczynski, James P. Solomon, Ebersberger, Johannes Leuchtweis, Takayuki Maruyama, Sarah Michael, Evan T. Powers, Jeffery W. Kelly, Amanda Gunther Olaf Hofmann, Karl-Jürgen Halbhuber, Roberts, Gary Tong, Traci Fang-Newmeyer, James Parker, and Hans-Georg Schaible Emily A. Holland, Dongxian Zhang, Nobuki Nakanishi, H.-S. Vincent Chen, Herman Wolosker, Yuqiang Wang, Loren H. PHYSIOLOGY Parsons, Rajesh Ambasudhan, Eliezer Masliah, Stephen F. 13654 Asymmetric transmitter binding sites of fetal muscle Heinemann, Juan C. Piña-Crespo, and Stuart A. Lipton acetylcholine receptors shape their synaptic response Tapan K. Nayak and Anthony Auerbach ix Subscription Form

viii u www.pnas.org Downloaded by guest on October 1, 2021