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Job Description and Person Specification Job Description and Person Specification Posts Academic Clinical Lecturership in Immunology or Clinical Oncology or Medical Oncology There is one NIHR funded post available in this round but additional locally funded posts may be awarded in parallel subject to funding and assessment against the stated criteria for the role Department (s) Nuffield Department of Medicine, Henry Wellcome Building for Molecular Physiology, Old Road Campus, Headington, Oxford OX3 7BN Department of Oncology, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ Division Medical Sciences Division Contract type Fixed term for four years Salary Grade A63 or A67: £33,790 - £59,765 per annum dependent on qualifications and experience, in line with current pay protection and transitional arrangements in the NHS Overview of the post The University of Oxford is able to offer a number of Academic Clinical Lecturerships annually to suitably qualified applicants. These posts have been awarded by the NIHR to University/Deanery/NHS Trust partnerships nationally. They form part of the NIHR Integrated Training Pathway, further details of which can be found on the NIHR website http://www.nihr.ac.uk/IAT The Academic Clinical Lecturership is the final phase of the Integrated Academic Training Pathway. The posts are designed to allow time to complete a period of post-doctoral research to enable progress towards an independent academic career whilst completing clinical training. Applicants for these posts will be Specialist Trainees who have completed or have submitted for a higher degree (PhD / DPhil / MD). Oxford has a successful clinical academic programme delivered by the Oxford University Clinical Academic Graduate School in which all joint clinical/academic trainees take part. For further information see http://www.oucags.ox.ac.uk/. There is a strong record of support for 1 Clinical Lecturers through access to internal funding for research training courses, consumables, and for technical/research nurse support for projects. Over the four years post holders, in discussion with the training committees and academic supervisors, will be able to undertake clinical duties in order to complete their clinical training. All Clinical Lecturers are awarded an NTN (a). Post holders will be expected to spend 50% of their time (averaged over four years) on clinical duties and 50% on post-doctoral research. The appointment will be for a fixed term of four years. However, if training is completed during the four years the appointment will end six months after completion of CCT. Please see the NIHR Academic Clinical Lecturerships’ Entry, Eligibility, and Exit Points from April 2019 (annexed for full information). Applications are particularly welcome from women and black and minority ethnic candidates, who are under-represented in academic posts in Oxford. General queries about the post should be addressed Ms Heledd Gwilym at [email protected] or telephone: +44 01865 282342. Informal enquiries can be made to: Immunology: Dr Siraj Misbah at [email protected] Clinical Oncology: Professor Mark Middleton at [email protected] Medical Oncology: Professor Mark Middleton at [email protected] All enquiries will be treated in strict confidence; they will not form part of the selection decision. The University of Oxford is a member of the Athena SWAN Charter to promote women in Science, Engineering, Technology and Medicine. The University holds an Athena SWAN bronze award at institutional level and both the Nuffield Department of Clinical Neurosciences and the Nuffield Department of Surgical Sciences holds a silver award. Contact [email protected] for further information about Athena SWAN at the University of Oxford. Duties of the post Immunology The Immunology programme will be based at the John Radcliffe Hospital in the Department of Immunology, an accredited and designated centre of clinical excellence for Clinical Immunology. TRAINING OBJECTIVES: 1. Successful application for a senior fellowship/award. The Lecturer will, under the supervision of a PI, design an appropriate research project, in translational immunology. The implementation of the work will enable acquisition of data suitable for an application for a senior fellowship award during year 3. 2. Continuation of the pursuit of an academic career: reviewing scientific papers, publication of pilot studies, submission to ethics committees and understanding advanced medical statistics. 3. Completion of training for CCT in Immunology, including success in FRCPath in Immunology (the exit examination for a CCT in Immunology). RESEARCH PROJECT: This will be undertaken under the supervision (as for a post-doctoral fellows) of a section leader in the Human Immunology Unit within the WIMM or The Nuffield Department of Medicine. Joint supervision is encouraged to facilitate translational research. The systemic functioning of immune 2 systems gives many opportunities for collaboration with organ-based specialists as well as clinician-scientists. The following principal investigators have offered translational projects: Dr Graham Ogg Prof Paul Klenerman Prof Lars Fugger Dr Sarosh Irani Prof Richard Cornall Prof Enzo Cerundulo Dr Smita Patel Dr Paul Bowness Prof David Jackson (Endothelial pathology) Prof Julian Knight . In addition, collaborations abroad (Karolinska Institute; Necker Hospital, Paris; University of Freiberg, National Institutes of Health, Bethesda) provide opportunities for secondment during a clinical training fellowship. Immunology services at the Oxford University Hospitals Foundation Trust: The Clinical Immunology Service covers the four counties of Berkshire, Buckinghamshire, Northamptonshire and Oxfordshire, making a population total of just under 3 million. The Department provides clinical and laboratory services to a population of 2.5million in the catchment area of the equivalent of the Thames Valley Strategic Health Authority. The NHS Department of Clinical Immunology provides a tertiary regional service to a population of ~1.4 million. It provides comprehensive treatment of immunological diseases, in particular primary and secondary immune deficiencies, systemic autoimmune disease and vasculitis (jointly with rheumatology) and complex allergies, including desensitisation immunotherapy. The department manages the Department of Health's demand management plan for Intravenous Immunoglobulin for a number of Trusts (OUH, Wexham Park, Milton Keynes GH, Buckinghamshire hospitals, Royal Berkshire Hospital) with one of the consultants designated as the lead. The department currently looks after 250 patients with primary antibody deficiency, 52 patients with C1 inhibitor deficiency, 50 patients with autoimmune neuropathies and 76 patients receiving desensitisation immunotherapy for insect venom allergy. The regional Immunology Laboratory, at the Churchill Hospital, provides a comprehensive diagnostic service. Clinical Immunology is accredited as a PID centre by UK Primary Immunodeficiency Network. The Laboratory is accredited by CPA (UK) Ltd and participates in all relevant EQA schemes. Immunology Clinics The post-holder will be closely involved in performing weekly clinics in Immunology and Allergy. In addition there are weekly paediatric infection and immunity, weekly venom desensitisation clinics, weekly drug allergy clinics, weekly connective tissue disease clinics and twice weekly immunoglobulin infusion clinics. Patients with primary immune deficiencies from the Central and South Central regions are seen in Oxford; there are no out-reach clinics. Ward referrals These consist of urgent requests for the assessment of children and adults with immunological diseases, for advice on diagnosis and /or management. These are covered by the consultants and junior clinical staff as appropriate. Access to inpatient beds for immunology patients is by arrangement with Infectious Diseases or the relevant organ-based specialty. 3 Oxford Immunology Service: the health professional team There are 3 consultant staff: Dr Siraj Misbah, Consultant Immunologist and Clinical Lead for Clinical Immunology Dr Smita Patel, Consultant Immunologist (Joint BRC-NHS appointment) Dr Rashmi Jain, Consultant Immunologist ALLOCATION OF PROTECTED ACADEMIC TIME IN BLOCKS OVER FOUR YEARS: Aim Year 1 Year 2 Year 3 year 4 Successful application for Senior Fellowship – protected time 26 26 24 22 Audit 0 6 4 4 Clinics 12 8 8 10 Secondments (e.g. Institute of Child Health) 0 0 6 6 Routine laboratory 8 6 4 4 Subtotal 46 46 46 46 Holidays 6 6 6 6 Total 52 52 52 52 This provides for 60 - 70% protected academic time in each of the four years, with a maximum early in the programme to enable the application to be made in the third year, in order to gain a senior fellowship. The CCT Immunology training will be completed in the last year. There is no on-call requirement for Immunology trainees, either academic or NHS. Application for Senior Clinical Fellowship Award once training is completed Prior to the beginning the first year, candidates for clinical lectureships will be expected to have discussed intended projects with appropriate supervisors, to have visited the laboratory. There will be time early in the first year to submit an ethics application and to set up the collaborations required. Implementation of the project will then be part-time for the second half of year 1 and throughout years 2 & 3. Slightly less time has been allocated in years 3 & 4, whilst secondments (twice
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