Proinsulin in Prolonged Fast
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Old Road Campus
Old Road Campus 4a, 4b, 4c, U5 n o t Oxford City Centre g OLD ROAD n i d 4a, 4b, 4c, U5 a e H K O L L A D R O W AD E M I L 4,4a,4b,4c, U1X,U5 A41 42 4,4a,4b,4c,U5 Rin D 4 g R oad 6 7 1 13 3 11 C H U R C H I L L 900 D 2 R I 700, 900 V E E O x f o 5 A C rd 12 C i ty 10 C e n t re B 8 CAR PARK C 9 h u r c R F h i O l l O S H E o V s N E p L i T t DRI a VE ENTRANCE ROOSEVELT DRIVE l 900, ST2 Index 1 The Triangle Nursery 9 Old Road Campus Estates Annexe 13 Boundary Brook House Interserve Joint Research Office Kennedy Institute 2 - Research Services, Medical Sciences Division Old Road Campus Research Building 10 - Clinical Trials and Research Governance 3 New Richards Building Department of Oncology - Human Tissue Governance CRUK/MRC Oxford Institute for Radiation Oncology - Medical Sciences Division Business Development 4 NDM Research Building Institute of Biomedical Engineering Nuffield Department of Primary Care Health Sciences Target Discovery Institute Jenner Institute Medical Sciences Divisional Safety Officers Centre for Tropical Medicine and Global Health Bodleian Knowledge Centre (Library Services) Medical Sciences Division IT Services 5 Wellcome Centre for Human Genetics (WHG) Ludwig Institute for Cancer Research Structural Genomics Consortium 6 Henry Wellcome Building for Molecular Physiology Nuffield Department of Surgical Sciences Loading Bays and Delivery Offices of the Nuffield Professor of Medicine ENTRANCE VIA BUILDING 5 11 Big Data Institute A Wellcome Trust Centre for Human Genetics 7 Henry Wellcome Building for Particle Imaging -
Endoscopy Disease Detection Challenge 2020
ENDOSCOPY DISEASE DETECTION CHALLENGE 2020 Sharib Ali1 Noha Ghatwary7 Barbara Braden2 Dominique Lamarque3 Adam Bailey 2 Stefano Realdon4 Renato Cannizzaro 5 Jens Rittscher1 Christian Daul6 James East 2 1 Institute of Biomedical Engineering, Big Data Institute, University of Oxford, Old Road Campus, Oxford, UK 2 Translational Gastroenterology Unit, Experimental Medicine Div., John Radcliffe Hospital, University of Oxford, Oxford, UK 3 Universite´ de Versailles St-Quentin en Yvelines, Hopitalˆ Ambroise Pare,´ France 4 Instituto Onclologico Veneto, IOV-IRCCS, Padova, Italy 5 CRO Centro Riferimento Oncologico IRCCS Aviano Italy 6 CRAN UMR 7039, University of Lorraine, CNRS, Nancy, France 7 University of Lincoln, UK ABSTRACT improve current medical practices and refine health-care Whilst many technologies are built around endoscopy, there systems worldwide. However, well-annotated, representative is a need to have a comprehensive dataset collected from publicly available datasets for disease detection for assessing multiple centers to address the generalization issues with research reproducibility and facilitating standardized com- most deep learning frameworks. What could be more im- parison of methods is still lacking. Many methods to detect portant than disease detection and localization? Through diseased regions in endoscopy have been proposed however our extensive network of clinical and computational experts, these have been primarily focused on the task of polyp we have collected, curated and annotated gastrointestinal detection in the gastrointestinal tract with demonstration on endoscopy video frames. We have released this dataset and datasets acquired from at most a few data centers and single have launched disease detection and segmentation challenge modality imaging, most commonly white light. Here, we EDD20201 to address the limitations and explore new di- present our multi-class, multi-organ and multi-population rections. -
Archaeology in Oxford Oxford City Report to the Oxford City and County Archaeological Forum February-June 2021
Archaeology in Oxford Oxford City report to the Oxford City and County Archaeological Forum February-June 2021 The impact of Covid 19 on archaeological work in the city The Urban Design and Heritage Team has continued to work remotely from home since the February OCCAF update with normal service levels being maintained. National Planning Policy Framework related field work in Oxford Armstrong Road, Littlemore Between January and May further intermittent archaeological excavation was undertaken around the site of Busy Bees Nursery on Armstrong Road by Oxford Archaeology. A number of pits of Early/Middle Iron Age date were recorded, forming part of a domestic settlement. Above: Early Iron Age pits recorded at Armstrong Road. Images courtesy of Oxford Archaeology. Warneford Hospital In February an evaluation trench was excavated by John Moore Heritage Services on land to the south of Warneford Hospital. The trench was required in advance of a hospital extension because of the potential Roman remains in this area, no significant archaeological remains were noted Old Road Campus Plot B1 In February trial trenching was undertaken by Oxford Archaeology prior to the construction of new University buildings at Old Road Campus. The work was required because of the general potential for prehistoric and Roman remains in this location. No significant archaeological deposits were noted. St Peter's College Castle Hill House, In February historic building recording was undertaken at Castle Hill House by Oxford Archaeology. The 19th century house is due to be demolished as part of the redevelopment of the site by St Peter’s College. The location of a documented 18th-19th century tunnel running under Bulwark’s Lane was confirmed (visible as a semi-circular damp patch in Bulwarks Lane) and recorded. -
Job Description and Person Specification
Job description and selection criteria Job title Statistician (for Biomedical Informatics) Division Medical Sciences The George Institute for Global Health / Nuffield Department Department of Population Health New Richards Building, Old Road Campus, Location Headington, Oxford Grade and salary Grade 7: £29,541 - £36,298 Hours Full-time or part-time (at least 50%) Contract type Fixed-term, 18 months Reporting to Dr Kazem Rahimi Vacancy 111004 reference Introduction The University The University of Oxford is a complex and stimulating organisation, which enjoys an international reputation as a world-class centre of excellence in research and teaching. It employs over 10,000 staff and has a student population of over 22,000. Most staff are directly appointed and managed by one of the University’s 130 departments or other units within a highly devolved operational structure - this includes over 6,500 ‘academic-related’ staff (postgraduate research, computing, senior library, and administrative staff) and over 2,700 ‘support’ staff (including clerical, library, technical, and manual staff). There are also over 1,600 academic staff (professors, readers, lecturers), whose appointments are in the main overseen by a combination of broader divisional and local faculty board/departmental structures. Academics are generally all also employed by one of the 38 constituent colleges of the University as well as by the central University itself. Our annual income in 2011/12 was £1,016.1m. Oxford is one of Europe's most innovative and entrepreneurial universities: income from external research contracts exceeds £409m p.a., and more than 80 spin-off companies have been created. For more information please visit www.ox.ac.uk/staff/about_the_university.html The Medical Sciences Division The Medical Sciences Division is an internationally recognized centre of excellence for biomedical and clinical research and teaching, and the largest academic division in the University of Oxford. -
Graduate Prospectus 2012–13
Graduate Prospectus 2012–13 cover - separate file www.ox.ac.uk/graduate inside front cover - separate file Produced by © The University of The photographs used within University of Oxford this prospectus were submitted Do you need this prospectus Oxford 2011 by current graduate students Public Affairs Directorate and recent alumni as part of in another format? Distributed by All rights reserved. No part a photography competition University of Oxford of this publication may be that took place in 2011. All Braille, large print and audio formats Graduate Admissions reproduced, stored in a photographs are credited to are available on request from: and Funding retrieval system, or the photographer where they University Offices, transmitted, in any form appear. Graduate Admissions and Funding Wellington Square, or by any means, Oxford OX1 2JD electronic, mechanical, Cover photograph by Greg Smolonski Tel: +44 (0)1865 270059 photocopying, recording, +44 (0)1865 270059 Photograph by Michael Camilleri, or otherwise, without Email: [email protected] graduate.admissions@ MSc Computer Science prior permission. admin.ox.ac.uk (St Anne’s College) Graduate Prospectus 2012–13 | 3 Welcome to Oxford Our graduate students are vital to the University of Oxford. They form part of the academic research community, and the teaching and training they receive sets them up to join the next generation of leaders and innovators. Graduate study at Oxford is a very special experience. Our graduate students have the opportunity to work with leading academics, and the University has some of the best libraries, laboratories, museums and Rob Judges collections in the world. -
University of Oxford Sustainability Report
5 tion W duc ate re r 7 on rb Ca 4 T 1 r a n v o i e t l a 8 c u d E University of Oxford Environmental W Sustainability a 3 s t 1 e g , Report n r i e s c a y h c c l r 2011/2012 i n u g p a e l n b d a r n e i a u t s s e u 1 S 0 2 1 s B g i n o i d d l i i v u e b r s e l i t b y a 1 n i 1 a t s u Sustainability S in colleges 15 BACK TO University of Oxford Environmental Sustainability Report 2011/12 2 CONTENTS Vice-Chancellor’s introduction This is the University’s second Environmental Sustainability Report, compiled by the “As Chair of the Sustainability Steering Group, University’s Sustainability Team. The report covers the University’s performance in I have seen a significant shift in staff and carbon emissions, business travel, water consumption, sustainable buildings, material students’ expectations of environmental resources, biodiversity and sustainable purchasing. It also sustainability over the past year. Energy We hope this highlights the diverse sustainability initiatives across the estate efficiency and carbon reduction are now report will help and future projects planned for 2013 onwards. considered ‘business as usual’ and an increasing number of staff want to reuse unwanted to communicate We hope this report will help to communicate the environmental office items rather than throw them away. -
The Jenner Institute Laboratories University of Oxford Old Road Campus Research Building Roosevelt Drive Oxford OX3 7DQ
The Jenner Institute Laboratories University of Oxford Old Road Campus Research Building Roosevelt Drive Oxford OX3 7DQ 1st May 2020 Dear Prof Gilbert, Thank you for the research of critical global importance which you and your team have undertaken into a potential vaccine for the SARS-CoV-2 virus. As patients and the families of people affected by COVID19, health workers, and public health and social justice campaigners, we are now writing this open letter to you with urgent questions about the licence agreement with Astra Zeneca announced yesterday. We believe that there should be no monopolies in the time of a pandemic - and they should never prevent patients getting affordable access to important diagnostics, medicines or vaccines. We kindly ask that you please respond to the following points: 1. Please make the full terms of the licence agreement with Astra Zeneca public, as has been normalised through the global public health standards set by the Medicines Patent Pool. 2. Can you please provide information on the patents related to the ChAdOx technologies, such as PCT application numbers and information about patent applications at national patent offices and the EPO? 3. Can you please confirm what safeguards have been included in the agreement to guarantee access and affordability for the NHS and for the billions across the world whose lives and livelihoods are threatened? 4. Can you assure us that the agreement with Astra Zeneca is a non-exclusive licence and that it will allow other manufacturers to make and supply quality-assured versions of the vaccine? 5. What efforts have been made to ensure non-patent based monopoly protections, such as regulatory exclusivities, are not enforced on this vaccine? 6. -
Panton-Valentine Leucocidin Is the Key Determinant of Staphylococcus
bioRxiv preprint doi: https://doi.org/10.1101/430538; this version posted September 29, 2018. The copyright holder for this preprint (which was not certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under aCC-BY-NC 4.0 International license. 1 Panton-Valentine leucocidin is the key determinant of Staphylococcus aureus 2 pyomyositis in a bacterial genome-wide association study 3 Bernadette C Young1,2, Sarah G Earle1, Sona Soeng3, Poda Sar3, Varun Kumar4, Songly Hor3, 4 Vuthy Sar3, Rachel Bousfield5, Nicholas D Sanderson1, Leanne Barker1, Nicole Stoesser1,6, 5 Katherine RW Emary2, Christopher M Parry7,8, Emma K Nickerson5, Paul Turner3,9, Rory 6 Bowden10, Derrick Crook1,2,6, David Wyllie1,6,11, Nicholas PJ Day9,13†, Daniel J Wilson1,10,12 †, 7 Catrin E Moore9,13†* 8 1 Nuffield Department of Medicine, Experimental Medicine Division, University of Oxford, 9 John Radcliffe Hospital, Oxford OX3 9DU, UK. 10 2 NIHR Oxford Biomedical Research Centre, Infection Theme, Oxford University Hospitals 11 NHS Foundation Trust, John Radcliffe Hospital, Oxford, OX3 9DU, UK. 12 3 Cambodia Oxford Medical Research Unit, Angkor Hospital for Children, Siem Reap, 13 Cambodia 14 4 Department of Pediatrics, East Tennessee State University Quillen College of Medicine, 15 Johnson City, USA 16 5 Department of Infectious Diseases, Cambridge University Hospitals NHS Foundation Trust, 17 Cambridge, CB2 0QQ, UK 18 6 Public Health England Academic Collaborating Centre, John Radcliffe -
Job Description and Person Specification
Job description and selection criteria Job title Research Nurse Division Medical Sciences The George Institute for Global Health/ Nuffield Department of Department Population Health Location New Richards Building, Old Road Campus, Headington, Oxford Grade and salary Grade 7: £29,837 - £36,661 p.a. Hours Full time (part-time considered) Contract type Fixed-term, 1 year Reporting to Dr Kazem Rahimi Vacancy reference 112109 Introduction The University The University of Oxford is a complex and stimulating organisation, which enjoys an international reputation as a world-class centre of excellence in research and teaching. It employs over 10,000 staff and has a student population of over 22,000. Most staff are directly appointed and managed by one of the University’s 130 departments or other units within a highly devolved operational structure - this includes over 6,500 ‘academic-related’ staff (postgraduate research, computing, senior library, and administrative staff) and over 2,700 ‘support’ staff (including clerical, library, technical, and manual staff). There are also over 1,600 academic staff (professors, readers, lecturers), whose appointments are in the main overseen by a combination of broader divisional and local faculty board/departmental structures. Academics are generally all also employed by one of the 38 constituent colleges of the University as well as by the central University itself. Our annual income in 2011/12 was £1,016.1m. Oxford is one of Europe's most innovative and entrepreneurial universities: income from external research contracts exceeds £409m p.a., and more than 80 spin-off companies have been created. For more information please visit www.ox.ac.uk/staff/about_the_university.html Medical Sciences Division The Medical Sciences Division is an internationally recognized centre of excellence for biomedical and clinical research and teaching. -
Plot B1, Old Road Campus, University of Oxford Biodiversity Net Gain Assessment Report
Intended for Associated Architects LLP Date May 2021 Project Number 1620009366 Document Number 9366-RAM-XX-XX-RP-EC-10020 PLOT B1, OLD ROAD CAMPUS, UNIVERSITY OF OXFORD BIODIVERSITY NET GAIN ASSESSMENT REPORT PLOT B1, OLD ROAD CAMPUS, UNIVERSITY OF OXFORD BIODIVERSITY NET GAIN ASSESSMENT REPORT Project No. 1620009366 Issue No. 1 Date 04/05/2021 Made by Iain Lednor Checked by Vikki Patton Approved by Vikki Patton Document 9366-RAM-XX-XX-RP-EC-10020 Number Made by: Checked/Approved by: This report is produced by Ramboll at the request of the client for the purposes detailed herein. This report and accompanying documents are intended solely for the use and benefit of the client for this purpose only and may not be used by or disclosed to, in whole or in part, any other person without the express written consent of Ramboll. Ramboll neither owes nor accepts any duty to any third party and shall not be liable for any loss, damage or expense of whatsoever nature which is caused by their reliance on the information contained in this report. Version Control Log Revision Date Made by Checked by Approved by Description 1 04/05/2021 IL VP VP First issue to client Ramboll 240 Blackfriars Road London SE1 8NW United Kingdom T +44 20 7808 1420 www.ramboll.co.uk BIODIVERSITY NET GAIN ASSESSMENT REPORT PLOT B1, OLD ROAD CAMPUS, UNIVERSITY OF OXFORD CONTENTS EXECUTIVE SUMMARY I 1. INTRODUCTION 1 1.1 Background 1 1.2 Biodiversity Net Gain 1 1.3 Objectives 2 1.4 Proposed Development 2 1.5 Local Plan Policy 3 1.6 Oxfordshire County Council 3 1.7 University of Oxford Policy 4 2. -
Job Description and Person Specification
Job Description and Person Specification Posts Academic Clinical Lecturership in Immunology or Clinical Oncology or Medical Oncology There is one NIHR funded post available in this round but additional locally funded posts may be awarded in parallel subject to funding and assessment against the stated criteria for the role Department (s) Nuffield Department of Medicine, Henry Wellcome Building for Molecular Physiology, Old Road Campus, Headington, Oxford OX3 7BN Department of Oncology, Old Road Campus Research Building, Roosevelt Drive, Headington, Oxford, OX3 7DQ Division Medical Sciences Division Contract type Fixed term for four years Salary Grade A63 or A67: £33,790 - £59,765 per annum dependent on qualifications and experience, in line with current pay protection and transitional arrangements in the NHS Overview of the post The University of Oxford is able to offer a number of Academic Clinical Lecturerships annually to suitably qualified applicants. These posts have been awarded by the NIHR to University/Deanery/NHS Trust partnerships nationally. They form part of the NIHR Integrated Training Pathway, further details of which can be found on the NIHR website http://www.nihr.ac.uk/IAT The Academic Clinical Lecturership is the final phase of the Integrated Academic Training Pathway. The posts are designed to allow time to complete a period of post-doctoral research to enable progress towards an independent academic career whilst completing clinical training. Applicants for these posts will be Specialist Trainees who have completed or have submitted for a higher degree (PhD / DPhil / MD). Oxford has a successful clinical academic programme delivered by the Oxford University Clinical Academic Graduate School in which all joint clinical/academic trainees take part. -
Controlling Intramolecular Interactions in the Design of Selective, High
Controlling Intramolecular Interactions in the Design of Selective, High-Affinity, Ligands for the CREBBP Bromodomain Michael Brand,† James Clayton,† Mustafa Moroglu,† Matthias Schiedel,† Sarah Picaud,‡ Joseph P. Bluck,†,§ Anna Skwarska,ǁ Anthony K. N. Chan,† Corentine M. C. Laurin,† Amy R. Scorah,† K. F. Larissa See,† Timothy P. C. Rooney,† Oleg Fedorov,‡ Gabriella Perell,# Prakriti Kalra,# Wilian A. Cortopassi,† Kirsten E. Christensen,† Richard I. Cooper,† Robert S. Paton,†,∇ William C. K. Pomerantz,# Philip C. Biggin,§ Ester M. Hammond,ǁ Panagis Filippakopoulos,‡ Stuart J. Conway†,* †Department of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford OX1 3TA, U.K. ‡Nuffield Department of Clinical Medicine, Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Roosevelt Drive, Oxford OX3 3TA, U.K. §Department of Biochemistry, University of Oxford, South ParKs Road, Oxford OX1 3QU, U.K. ǁOxford Institute for Radiation Oncology, Department of Oncology, University of Oxford, Oxford, OX3 7DQ, U.K. #Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, U.S.A. ∇Department of Chemistry, Colorado State University, 1301 Center Ave, Ft. Collins, CO 80523- 1872, U.S.A. *To whom correspondence should be addressed: [email protected] 1 Michael Brand 0000-0002-6998-0516 James Clayton 0000-0002-9126-4030 Mustafa Moroglu 0000-0003-4841-9241 Matthias Schiedel 0000-0001-7365-3617 Sarah Picaud 0000-0002-3803-4455 Anthony K. N. Chan 0000-0002-7091-1294 Corentine M.C. Laurin 0000-0001-8808-9406 Joseph P. Bluck 0000-0001-9170-5919 Amy R. Scorah 0000-0001-7327-4502 Larissa See 0000-0002-7192-9007 Timothy P.