Issue 85 of the Genetics Society Newsletter

Total Page:16

File Type:pdf, Size:1020Kb

Issue 85 of the Genetics Society Newsletter JULY 2021 | ISSUE 85 GENETICS SOCIETY NEWS In this issue The Genetics Society News is edited by • Presidential handover Margherita Colucci and items for future • Genetics Society Summer Studentship - Share your story, Part 1 issues can be sent to the editor by email • A chat with Dr Stuart Ritchie - Exploring “Science fictions” to [email protected]. • Committee on Mutagenicity of Chemicals in Food, Consumer The Newsletter is published twice a year, Products and the Environment (COM) with copy dates of July and January. • How genetic linkage was discovered Genetics Society Summer Studentship - Share your stories, Part 1. Read the interviews on page 27 A WORD FROM THE EDITOR A word from the editor Welcome to Issue 85 elcome to the latest issue of the world that cry for change: with WGenetics Society Newsletter! Dr Stuart Ritchie, we explore In this issue, “change” is the keyword. misconduct and fraud in science and the solutions that “open science” Through a series of interviews, we proposes, talking about his latest explored the changes from their book “Science fictions: how fraud, undergraduate role and the career bias, negligence and hype undermine evolution of the past years Summer the search for truth”. Studentship grant winners. Where are they now? What impact that research I would like to draw your attention experience had on them? Find out to the opportunity of contributing more in “Genetics Society Summer to the special issue of Heredity. In Studentship - Share your story, July 2022, this special issue will be Part 1”, page 23. celebrating Mendel’s 200th birthday with short essays, reviews and Big changes happened in the Society research articles on “exceptions” too. While we say goodbye to our to Mendel’s laws. We would like to previous president, Laurence Hurst, invite you to submit your piece (more and thank him for all his great work information on page 20). and dedication to the society, we have welcomed our new President, Anne Looking forward to this special issue, Ferguson-Smith. Anne is the Pro- we propose “How genetic linkage Vice-Chancellor for Research and the was discovered” by Antonio Marco Arthur Balfour Professor of Genetics (page 39): focusing on Mendel’s laws at the University of Cambridge. She is of heredity, this is an overview of the an expert on genomic imprinting and discovery of genetic linkage in which focuses on mammalian developmental William Bateson, the founder of The geneticist and epigeneticist. Please, go Genetics Society, was also involved. to page 22 to know more about her Enjoy! and what she hopes to achieve over the Best wishes, next 3 years. Margherita Colucci Finally, there are aspects in research and, more generally, in the scientific 2 . GENETICS SOCIETY NEWS . ISSUE 85 ISSUE 85 . July 2021 For more details please contact: The Genetics Society 1 Naoroji Street London WC1X 0GB CONTENTS Switchboard: +44 0203 793 7850 Email: [email protected] Web: www.genetics.org.uk The Genetics Society Journals Meeting Announcements 4 Heredity Genetics Society Scientific Meetings www.nature.com/hd External Meetings Diary Editor-in-Chief: Prof Barbara Mable Heredity Editorial Office, University of Glasgow, Sectional Interest Groups 8 Graham Kerr Building, Glasgow, G12 8QQ, Scotland Genes and Development Genetics Society Business 13 www.genesdev.org Honorary Secretary’s Notices Editor: Dr Terri Grodzicker Life Membership Genes & Development, Cold Spring Harbor Laboratory Press, Lecture and Medal nominations 500 Sunnyside Boulevard, Woodbury, New York, 11797, USA Local Representatives Committee members Features 22 President Prof Anne Ferguson-Smith, University of Cambridge Presidential handover A chat with Dr Stuart Ritchie - Exploring “Science fictions: Vice-Presidents how fraud, bias, negligence and hype undermine the Corporate Affairs search for truth” Prof Aziz Aboobaker, University of Oxford Genetics Society Summer Studentship - Share your story External Relations Prof Anne Donaldson, University of Aberdeen Industrious Science: A day in the work-life of a Chief Public Understanding of Genetics Executive Officer, Jackeline Palma Prof Alison Woollard, University of Oxford How genetic linkage was discovered Honorary Secretary & Website Editor Committee on Mutagenicity of Chemicals in Food, Dr Kay Boulton, The Roslin Institute, University of Edinburgh Consumer Products and the Environment (COM) Honorary Treasurer Grant Reports 52 Dr Alexander Lorenz, University of Aberdeen One-off Meeting Reports Policy Officer Training Grant Reports Prof Rebecca Oakey, King’s College London Heredity Fieldwork Grant Report Scientific Meetings Secretary Genes and Development Summer Studentships Prof Stefan Hoppler, University of Aberdeen Contacting the Genetics Society 73 Newsletter Editor Margherita Colucci, University of Leicester Postgraduate Representative Ms Emily Baker, University of Oxford Ordinary Committee Members Gene Structure, function and regulation Dr Michelle Holland, King’s College London Dr Cristina Tufarelli, University of Leicester Genomics Dr Araxi Aruttia Odobachian, University of Bath Dr Colin Semple, University of Edinburgh Cell and Develomental Genetics Prof Paola Olivieri, University College London Prof Ros John, Cardiff University Applied and Quantitative Genetics Dr Lindsey Compton, University of Birmingham Prof Alastair Wilson, University of Exeter Evolutionary, ecological and population genetics Prof Jason Wolf, University of Bath Dr Maxim Kapralov, Newcastle University Corporate Genetics and Biotechnology Dr Alison Bentley, NIAB / CIMMYT Dr Marcus Guest, Sygenta Design and Print Collaborate Agency www.collaborate.agency www.genetics.org.uk . 3 GENETICS SOCIETY SCIENTIFIC MEETINGS 4 Meetings Announcements More detailed information and links to event websites can be found at www.genetics.org.uk/events_categories/conferences/ Genetics Society Carer’s Award It has become clear over the past five years that the genetic basis of these diseases does not primarily affect In recognition of carer’s responsibilities, an award of (up regions of the human genome that code for proteins but to) £60/day will be made available to enable members may affect the much larger part of the genome, called the and selected speakers to attend Genetics Society scientific regulatory genome, that controls where, when and by meetings and events (including virtual events). Awardees how much the expression of genes are turned on and off. can spend this money as they think will best support However, compared to protein coding sequences, which their attendance. Applications can be made through the make up only 1.5% of the human genome, the regulatory mysociety portal. genome remains poorly understood. Thus, the focus of this conference will be to invite Functional Regulatory Genomics international leaders in the interdisciplinary study of and Disease the genetics of disease, the exploration of the regulatory genome and the in-depth biology of its activity and Date: 15-17 November, 2021 function, to interact and discuss their work. Location: Hadyn Ellis Building, Maindy Road, By doing so it is hoped that we can reach a consensus on Cardiff University, Cardiff how we might coordinate international interdisciplinary Website: genetics.org.uk/events/functional-regulatory- efforts to understand the role of the regulatory genome in genomics-disease health and disease. Info: Complex heritable conditions such as obesity, diabetes, alcohol abuse, schizophrenia and depression affect a significant proportion of the UK population. REGISTER FOR MORE GENETICS SOCIETY EVENTS AT: www.genetics.org.uk 4 . GENETICS SOCIETY NEWS . ISSUE 85 5 EXTERNAL MEETINGS DIARY More detailed information and links to event websites can be found at www.genetics.org.uk/events_categories/external-meetings. We will happily include any announcements for genetics-based meetings in this section. Please send any items to [email protected]. CRISPR and Beyond: Perturbations at Scale to of viruses and will address the fundamental questions of viral Understand Genomes (Virtual Conference) origins, transmission and pathogenesis. Date: 1-3 September, 2021 Sessions will run online in afternoons for Europe and Africa Deadlines: 20 July, 2021 (Abstract and Bursary); | mornings for the Americas, enabling participation of 23 August, 2021 (Registration) evolutionary biologists, bioinformatics and public health Location: Online practitioners from across the globe. Website: https://coursesandconferences. This year’s meeting will focus on virus evolution, epidemics wellcomeconnectingscience.org/event/ and outbreaks and emerging viral infections and zoonoses. We Info: The development of CRISPR/Cas-based technologies will also explore new technologies to analyse viruses and large and DNA synthesis make it possible to modulate genomes datasets and discuss diagnostic methods to improve public with relative ease. These tools can help us understand how health. genetic variation influences phenotype and thereby answer long-standing questions in biology that impact human health, The 14th Annual Royal Marsden Breast Cancer laying the foundations for precision medicine for heritable Virtual Meeting: Hot Topics in Breast Cancer diseases and cancer treatment. Date: 8 October, 2021 This rapid advancement in gene-editing technology enables us Location: Online to begin to understand the functional implications of natural Website: https://www.royalmarsden.nhs.uk/14th-annual- and disease-related human genetic variation. This year’s royal-marsden-breast-cancer-virtual-meeting-hot-topics-
Recommended publications
  • From the President's Desk
    JAN/FEB 2006 From the President’s desk: 2006, the 75th anniversary of the Genetics Society of America, will be marked by a number of initiatives to reinvigorate the Society’s mission of promoting research and education in genetics. A highlight was the recently held GSA sponsored conference, “Genetic Analysis: From Model Organisms to Human Biology” in San Diego from January 5-7. This conference emphasized the importance of model organism research by illustrating the crucial contributions to human biology resulting from discoveries in these organisms. The National Institutes of Health (NIH) supported this conference both financially and by participation of key NIH administrators, including Jeremy M. Berg, director of the National Institute of General Medical Sciences. In addition to the superb science talks by international leaders the MOHB conference showcased other important and new GSA initiatives including education, public policy advocacy, graduate student support and recognition of outstanding model organism geneticists. Robin Wright, Education Committee chair, led a round table discussion on undergraduate education and the Joint Steering Committee for Public Policy and the Congressional Liaison Committee sponsored a session on science advocacy and public policy. There was a mentor lunch to support graduate students and postdocs in the next steps of their careers, and the three GSA medals were presented during the banquet, with Victor Ambros receiving the GSA Medal, Fred Sherman the Beadle Award, and Masatoshi Nei the Morgan Award. (For research highlights at the meeting, see pages 6 and 7 of this issue.) The 75th anniversary will also usher in changes to our society’s journal, GENETICS.
    [Show full text]
  • Newsletter 09/07 DIGITAL EDITION Nr
    ISSN 1610-2606 ISSN 1610-2606 newsletter 09/07 DIGITAL EDITION Nr. 206 - April 2007 Michael J. Fox Christopher Lloyd LASER HOTLINE - Inh. Dipl.-Ing. (FH) Wolfram Hannemann, MBKS - Talstr. 3 - 70825 K o r n t a l Fon: 0711-832188 - Fax: 0711-8380518 - E-Mail: [email protected] - Web: www.laserhotline.de Newsletter 09/07 (Nr. 206) April 2007 editorial Hallo Laserdisc- und DVD-Fans, und Fach. Wie versprochen gibt es dar- diesem Editorial auch gar nicht weiter liebe Filmfreunde! in unsere Reportage vom Widescreen aufhalten. Viel Spaß und bis zum näch- Es hat mal wieder ein paar Tage länger Weekend in Bradford. Also Lesestoff sten Mal! gedauert, aber nun haben wir Ausgabe satt. Und damit Sie auch gleich damit 206 unseres Newsletters unter Dach beginnen können, wollen wir Sie mit Ihr LASER HOTLINE Team LASER HOTLINE Seite 2 Newsletter 09/07 (Nr. 206) April 2007 US-Debüt der umtriebigen Pang-Brüder, die alle Register ihres Könnens ziehen, um im Stil von „Amityville Horror“ ein mit einem Fluch belegtes Haus zu Leben zu erwecken. Inhalt Roy und Denise Solomon ziehen mit ihrer Teenager-Tochter Jess und ihrem kleinen Sohn Ben in ein entlegenes Farmhaus in einem Sonnenblumenfeld in North Dakota. Dass sich dort womöglich übernatürliche Dinge abspielen könnten, bleibt von den Erwachsenen unbemerkt. Aber Ben und kurz darauf Jess spüren bald, dass nicht alles mit rechten Dingen zugeht. Weil ihr die Eltern nicht glauben wollen, recherchiert Jess auf eigene Faust und erfährt, dass sich in ihrem neuen Zuhause sechs Jahre zuvor ein bestialischer Mord abgespielt hat. Kritik Für sein amerikanisches Debüt hat sich das umtriebige Brüderpaar Danny und Oxide Pang („The Eye“) eine Variante von „Amityville Horror“ ausgesucht, um eine amerikanische Durchschnittsfamilie nach allen Regeln der Kunst mit übernatürlichem Terror zu überziehen.
    [Show full text]
  • Genetics Society News
    July 2008 . ISSUE 59 GENETICS SOCIETY NEWS www.genetics.org.uk IN THIS ISSUE Genetics Society News is edited by Steve Russell. Items for future issues should be sent to Steve Russell, preferably by email to • Genetics Society Epigenetics Meeting [email protected], or hard copy to Department of Genetics, • Genetics Society Sponsored Meetings University of Cambridge, Downing Street, Cambridge CB2 3EH. The Newsletter is published twice a year, with copy dates of 1st June and • Travel, Fieldwork and Studentship Reports 26th November. • John Evans: an Appreciation Cocoons of the parasitoid wasp Cotesia vestalis on cabbage leaf in Taiwan. From the • Twelve Galton Lectures fieldwork report by Jetske G. de Boer on page 36. • My Favourite Paper A WORD FROM THE EDITOR A word from the editor ow soon until the $1000 based on the results of tests we genome is actually with barely understand! Here in the Hus and individual UK there is currently a sequencing is widespread? The moratorium, adhered to by publication of increasing most insurers, on the use of numbers of individual human genetic testing information for genome sequences suggests assessing life insurance that we should start to consider applications. It is important some of the implications that this remains in place and associated with the availability its effectiveness is reviewed of personal genetic well before the current information. In this issue we moratorium expires in 2011. present two articles reflecting The Human Genetics on his issue: a report from a Commission Genetics Society sponsored (http://www.hgc.gov.uk) meeting recently held in monitor issues relating to Cambridge organised by The genetic discrimination in the Triple Helix, an international UK and are a point of contact undergraduate organisation, as for those with any concerns in the Millennium Technology Prize.
    [Show full text]
  • A&E Television Networks, Comedy Central, Hanson
    A&E Television Networks, Comedy Central, Hanson, Marketplace And The Oakland A's Team With Yahoo! To Create Personal Web Communities From Entertainment and Comedy to Finance, Rock & Pop and Sports, Yahoo!® Clubs Offers a Community for Everyone SANTA CLARA, Calif. -- August 27, 1998 -- Yahoo! Inc. (NASDAQ: YHOO) today unveiled the latest additions to its customized communities of Yahoo! Clubs (http://clubs.yahoo.com), a new community building service giving users an opportunity to develop and grow relationships with others who share a common bond or interest. Beginning today, fans and followers can check out and join hot new clubs including personalized hubs for A&E's popular BIOGRAPHY® television series; The History Channel; a line-up of clubs from Comedy Central's top-rated shows including "South Park," "Dr. Katz: Professional Therapist," "Viva Variety," "The Daily Show," and "Upright Citizens Brigade;" The Hanson Club formed by the multi-platinum pop/rock band Hanson; a forum for business and finance offered by USC's Marketplace Radio, which airs on public radio stations throughout the U.S.; and a baseball team club for fans of the Oakland A's. These new clubs offer Yahoo! users an ideal way to connect with others in one central location. Using Yahoo! Clubs, people can chat in real-time with others who share the same adoration or interests; get the latest news or gossip; check out upcoming shows, events, episodes or concert schedules; post messages; send a group e-mail to everyone in the club; and even create their own directory of relevant Web site links.
    [Show full text]
  • Issue 84 of the Genetics Society Newsletter
    JANUARY 2021 | ISSUE 84 GENETICS SOCIETY NEWS In this issue The Genetics Society News is edited by • Non-canonical Careers: Thinking Outside the Box of Academia and Industry Margherita Colucci and items for future • Celebrating the 35th anniversary of DNA fingerprinting issues can be sent to the editor by email • Genetics Society Summer Studentship Workshop 2020 to [email protected]. • 2020 Heredity best student-led paper prize winners The Newsletter is published twice a year, • Industrious Science: interview with Dr Paul Lavin with copy dates of July and January. Celebrating students’ achievements: 2020 Genetics Society Summer Studentship Workshop, 2020 Heredity best student-led paper prize. Page 30 A WORD FROM THE EDITOR A word from the editor Welcome to Issue 84 elcome to the latest issue of the Thinking Outside the Box of WGenetics Society Newsletter! Academia and Industry”. This little This issue is packed with great news vade mecum for careers in genetics of achievements and good science. The collects inspiring interviews led first Genetics Society virtual workshop by our very own Postgraduate for the 2020 Summer studentship saw Representative, Emily Baker. In exceptional contributions from the Emily’s words, these experiences attending students. You can read more “demonstrate how a PhD in genetics about participants’ experiences in the can be a platform for a career in just interviews with the talk’s winners in about anything. Pursuing a career the Feature section. in academia, industry, publishing or science communication could be for Many more prizes were awarded: you, but so could many others. Why Heredity journal announced the not take a career path less travelled 2020 Heredity best student-led paper by, it might make all the difference?” winners, and James Burgon’s Heredity podcast dedicated an episode to the Enjoy! first prize winner, with insights from Best wishes, Heredity Editor-in-Chief, Barbara Margherita Colucci Mable.
    [Show full text]
  • 100 Years of Genetics
    Heredity (2019) 123:1–3 https://doi.org/10.1038/s41437-019-0230-2 EDITORIAL 100 years of genetics Alison Woollard1 Received: 27 April 2019 / Accepted: 28 April 2019 © The Genetics Society 2019 The UK Genetics Society was founded on 25 June 1919 and “biometricians”; the Genetical Society was very much a this special issue of Heredity, a journal owned by the society of Mendelians. Remarkably, 16 of the original 87 Society, celebrates a century of genetics from the perspec- members were women—virtually unknown in scientific tives of nine past (and present) presidents. societies at the time. Saunders was a vice president from its The founding of the Genetical Society (as it was then beginning and its 4th president from 1936–1938. Perhaps known) is often attributed to William Bateson, although it the new, and somewhat radical, ideas of “genetics” pre- was actually the brain child of Edith Saunders. The enthu- sented a rare opportunity for women to engage in research siasm of Saunders to set up a genetics association is cited in because the field lacked recognition in universities, and was the anonymous 1916 report “Botany at the British Asso- therefore less attractive to men. 1234567890();,: 1234567890();,: ciation”, Nature, 98, 2456, p. 238. Furthermore, the actual Bateson and Saunders (along with Punnett) were also founding of the Society in 1919 “largely through the energy influential in the field of linkage analysis (“partial coupling” as of Miss E.R Saunders” is reported (anonymously) in they referred to it at the time), having made several observa- “Notes”, Nature, 103, 2596, p.
    [Show full text]
  • Issue 82 of the Genetics Society Newsletter
    JANUARY 2020 | ISSUE 82 GENETICS SOCIETY NEWS In this issue The Genetics Society News is edited by Margherita Colucci and items for future • Medal and Prize Lecture Announcements issues can be sent to the editor by email • “A Century of Genetics” conference to [email protected]. • Celebrating the centenary of Fisher 1918 The Newsletter is published twice a year, • Research and travel grant reports with copy dates of July and January. Speakers’ dinner at the “A Century of Genetics” conference, November 2019, Edinburgh. (Photo by Douglas Vernimmen) A WORD FROM THE EDITOR A word from the editor Welcome to Issue 82 elcome to the latest issue of reports in the Sectional Interest Wthe GenSoc Newsletter and Groups: Reports section. my first steps (pages?) as new editor. And why not (re)discovering another I am eager to start this journey with great milestone such as the publishing you through the latest Genetics of Fisher’s 1918 paper, “The correlation Society achievements and genetics between relatives on the supposition news! I would like to thank all of Mendelian inheritance”, recently GenSoc committee for giving me this reaching its centenary recurrence? opportunity. I am sure you will greatly enjoy the In this issue, I will bring you back to report in the Features section. the inspiring and lively atmosphere Enjoy! of the GenSoc meeting ‘A Century of Genetics’ in Edinburgh (November Best wishes, 2019) - a really big thanks to all of those Margherita Colucci who kindly contributed. Many Sectional Interest groups have been very active: you will find their In this issue, I will bring you back to the inspiring and lively atmosphere of the GenSoc meeting “A Century of Genetics” in Edinburgh (November 2019) - a really big thanks to all of those who kindly contributed.
    [Show full text]
  • Perspectives
    Copyright Ó 2007 by the Genetics Society of America Perspectives Anecdotal, Historical and Critical Commentaries on Genetics Edited by James F. Crow and William F. Dove R. A. Fisher’s 1943 Unravelling of the Rhesus Blood-Group System A. W. F. Edwards1 Gonville and Caius College, Cambridge CB2 1TA, United Kingdom VEN if R. A. Fisher’s elucidation of the human blood- binatorial skills and his relations with A. S. Wiener, and E group system Rhesus in terms of the three linked to add a personal coda. It is best to take first the diagram loci C, D, and E had not proved to be substantially (Figure 1) from Fisher (1947) because it explains the correct, it would still have been an outstanding example relationship between the original Rhesus notation and of the power of analytical thought to unravel a complex that proposed by Fisher. As Fisher writes, ‘‘We may repre- array of genetical data. In fact, as a recent review relates sent the eight heritable antigen complexes geometrically (Avent et al. 2006), D is one gene (carrying the D anti- as the corners of a cube, while the six elementary antigens gen) and C and E are different splicing forms of another are represented by the faces; each allelomorphic pair of (CE carrying the C or c antigens and the E or e antigens). antigens is then a pair of opposite faces, and the three Fisher’s solution is recognizable beneath the modern faces meeting in any point specify the antigens in each molecular detail. complex.’’ (Ry) and (CdE) are in parentheses because The story of the unravelling of the Rhesus puzzle is the anti-d antibody had not yet been discovered (nor has told in chapter 13 of Joan Fisher Box’s R.
    [Show full text]
  • Genetics Society of America
    Genetics Society of America 1992 Records, Proceedings and Reports Published as supplementary material in GENETICS, Volume 131 Prepared by The Secretary Shirleen Roeder Department of Biology Yale University New Haven, Connecticut s2 BOARDS, COMMITTEES AND REPRESENTATIVES FOR 1992 BOARD OF DIRECTORS John C. Lucchesi, President Karen Artzt A. Dale Kaiser, Vice-president Welcome Bender Shirleen Roeder, Secretary Nina V. Fedoroff Carol S. Newlon, Treasurer Barry S. Ganetzky Leland H. Hartwell, Past President Christine Guthrie John W. Drake, Editor H. Robert Horvitz GENETICSEDITORIAL BOARD John W. Drake, Editor Maureen R. Hanson Sally Lyman Allen Robert K. Herman Karen Artzt Alan G. Hinnebusch Douglas E. Berg Richard R. Hudson David Botstein Nancy A. Jenkins John E. Boynton Mark Johnston Anthony H. D. Brown Elizabeth Jones Benjamin Burr Cathy C. Laurie Marian Carlson Wen-Hsiung Li Deborah Charlesworth Trudy F. C. Mackay Peter Cherbas Patricia J. Pukkila Arthur Chovnick Trudi Schiipbach Andrew G. Clark William F. Sheridan Thomas W. Cline Michael J. Simmons Rowland H. Davis Montgomery Slatkin Robin E. Denell Gerald R. Smith Norman R. Drinkwater Steven D. Tanksley Walter F. Eanes Elizabeth Thompson Victoria G. Finnerty Bruce S. Weir Margaret T. Fuller Fred Winston Roger E. Ganschow ADMINISTRATIVE OFFICE Elaine Strass, Executive Director Barbara Abbott, Publicat~nsAssistant/ASHG Membership Coordinator Sharon Adler, Accounting Assistant Judy Ashton, Oflce Coordinator Candis Galkin, Accounting Assistant Gloria Garber, Membership and Meetings Assistant Karen Gould, Comptroller/Manager of Administration Margot Kiley, GSA Membership Coordinator Krista Koziol, Publications Manager Anne Marie Langevin, GSA Meetings Manager Marsha Ryan, ASHG Meetings Manager Jane Salomon, ASHG Special Projects Manager COMMITTEES Leland H.
    [Show full text]
  • Laboratory III Linkage
    Genetics Laboratory III Biology 303 Spring 2007 Linkage Dr. Wadsworth Introduction same chromosome, the meiotic assortment of chromosomes alone would not predict the Genes are arranged as units in a linear order independent assortment of genes on those along chromosomes. The position of each gene chromosomes. In the absence of gene along the chromosome is called its locus. Each assortment, we would predict that the progeny gene has a unique chromosomal position and could only have the allelic combinations that therefore a unique locus. In fact, geneticists were present in the parent chromosomes. Genes often use the term genetic locus interchangeably that do not assort are said to show complete with the term gene. linkage. Alternatively, genes that independently assort are said to be unlinked. For the following The relative position of genes along a two examples, compare the genotypes and chromsomes can be analyzed by determining phenotypes generated in a dihybrid crosses of their linkage relationship. The concept of unlinked and completely linked genes. genetic linkage is outlined in this handout and will be discussed in class in the coming weeks. The position of a gene on a chromosome can be Example 1: A dihybrid cross for genes A and B, establish its identity. two unlinked genes. Generation Genotypes Phenotypes Specific Goals P1 AABBXaabb AB and ab 1. Conduct appropriate genetic crosses with a F1 AaBb AB mutant D. melanogaster to determine the following: F2 1AABB:2AABb: 9AB:3Ab:3aB:1ab 2AaBB:4AaBb:1AAbb: 2Aabb:1aaBB:2aaBb:1aabb a. Segregation b. Independent Assortment/Linkage Phenotypic ratio from dihybrid cross for c.
    [Show full text]
  • SAB Comedians Michael Ian Black and Mike Birbiglia Set to Perform
    Vol. 15 No. 13 NovembertodayJANUARY 30,88, 20102008 TrumanA weekly newsletter for students, faculty and staff Vol. 10 No. 34 today GROUP PROJECTS SAB Comedians Michael Ian Black and ENHANCED WITH Mike Birbiglia Set to Perform Dec. 11 OOGLE PPS G A omedians Michael Ian Black and Mike his 2009 hit show “Sleepwalk With Me.” Birbiglia tudies show that today’s CBirbiglia will perform at 7 p.m. Dec. 11 in closed out 2009 with a 35-city Comedy Central Sstudents and instructors Baldwin Hall Auditorium. Live tour called “Mike Birbiglia: I’m In The are increasingly turning Michael Ian Black is a multi-talented actor, Future Also,” selling out concert halls nationwide. to collaborative or group writer, comedian and director. His most recent His long-standing relationship with Comedy assignments to create significant comedy series, Central has resulted in three of his own standup and authentic learning “Michael and specials, including the critically acclaimed one- experiences. Michael Have Issues,” hour special “What I Should Have Said Was However, group projects are appeared on Comedy Nothing.” At the end of the year, Birbiglia’s 2007 not always easy to coordinate. Central this past year. Comedy Central Records release “My Secret Enter Google Apps: tools Black also created, Public Journal Live” was named one of the “Best available at Truman for starred in and co- Comedy Albums of students and teachers to easily wrote the Comedy the Decade” by The work asynchronously and Central series “Stella.” Onion AV Club. collaboratively on documents, He is also one of the Tickets for this presentations, drawings and lead commentators event are available whole websites.
    [Show full text]
  • Revise Meiosis Process and the Relation Between Mendel Laws and Meiosis Before Proceeding with This Lecture
    Genetics (BTBio 211) Lecture 3 part 2 2015-2016 Revise Meiosis process and the relation between Mendel laws and Meiosis before proceeding with this lecture. Meiosis Action: For each Parent 2 Chromosomes 2 Chromatids each 2 Chromosomes 1 Chromosome each 4 gametes: 4 Chromatid s 4 Chromatids each 1 Chromosome each each 1 Chromatids each 1 Genetics (BTBio 211) Lecture 3 part 2 2015-2016 LINKAGE AND CHROMOSOME MAPPING IN EUKARYOTES I. LINKAGE Genetic linkage is the tendency of genes that are located proximal to each other on a chromosome to be inherited together during meiosis. Genes whose loci are nearer to each other are less likely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be genetically linked. Linked genes: Genes that are inherited together with other gene(s) in form of single unit as they are located on the same chromosome. For example: in fruit flies the genes for eye color and the genes for wing length are on the same chromosome, thus are inherited together. A couple of genes on chromosomes may be present either on the different or on the same chromosome. 1. The independent assortment of two genes located on different chromosomes. Mendel’s Law of Independent Assortment: during gamete formation, segregation of one gene pair is independent of other gene pairs because the traits he studied were determined by genes on different chromosomes. Consider two genes A and B, each with two alleles A a and B b on separate (different) chromosomes. 2 Genetics (BTBio 211) Lecture 3 part 2 2015-2016 Gametes of non-homologous chromosomes assort independently at anaphase producing 4 different genotypes AB, ab, Ab and aB with a genotypic ratio 1:1:1:1.
    [Show full text]