June 19, 2012 u vol. 109 u no. 25 u 9667–10124

Cover image: Pictured is a thin polymer sheet floating on a drop of water, pulled taut from the edges by the liquid’s surface tension. Hunter King et al. report that when the drop swells beyond a critical curvature, the sheet accommodates the imposed spherical shape by wrinkling along its edge. The findings suggest that complexity of shape develops via the fundamentally different symmetry-breaking instabilities of wrinkling and crumpling. See the article by King et al. on pages 9716–9720. Image courtesy of Hunter King. From the Cover

9716 Mechanics of wrinkling and crumpling 9692 Genomics and theoretical ecology 9775 Life satisfaction and economic growth 9786 Tumors and implanted stem cells 9857 Lysin targets Gram-negative bacteria

Contents COMMENTARIES 9670 Economic growth and the human lot THIS WEEK IN PNAS John Knight See companion article on page 9775

9667 In This Issue 9672 Moving the O-glycoproteome from form to function Jacques U. Baenziger LETTERS (ONLINE ONLY) See companion article on page 9893

E1587 Evidence that publication bias contaminated studies relating social class and unethical behavior Gregory Francis PNAS PLUS (AUTHOR SUMMARIES)

E1588 Reply to Francis: Cumulative power calculations are PHYSICAL SCIENCES faulty when based on observed power and a small sample of studies APPLIED PHYSICAL SCIENCES Paul K. Piff, Daniel M. Stancato, Stéphane Côté, Rodolfo Mendoza-Denton, and Dacher Keltner 9678 Energetics of stalk intermediates in membrane fusion are controlled by lipid composition E1589 Flawed analysis of the possibility of air capture Sebastian Aeffner, Tobias Reusch, Britta Weinhausen, Matthew J. Realff and Peter Eisenberger and Tim Salditt See full research article on page E1609 of www.pnas.org E1590 Reply to Realff and Eisenberger: Energy requirements of air capture systems Howard J. Herzog, Kurt Zenz House, Antonio C. Baclig, BIOLOGICAL SCIENCES Ernst A. van Nierop, and Jennifer Wilcox AGRICULTURAL SCIENCES 9674 Single amino acid mutation in an ATP-binding cassette QNAS transporter gene causes resistance to Bt toxin Cry1Ab in the silkworm, Bombyx mori 9669 QnAs with Shu Chien Shogo Atsumi, Kazuhisa Miyamoto, Kimiko Yamamoto, Sandeep Ravindran Junko Narukawa, Sawako Kawai, Hideki Sezutsu, Isao Kobayashi, Keiro Uchino, Toshiki Tamura, Kazuei Mita, Keiko Kadono-Okuda, Sanae Wada, Kohzo Kanda, Marian R. Goldsmith, and Hiroaki Noda Free online through the PNAS open access option. See full research article on page E1591 of www.pnas.org

PNAS u June 19, 2012 u vol. 109 u no. 25 u iii–viii Downloaded by guest on September 27, 2021 BIOCHEMISTRY PHYSICAL SCIENCES 9676 Engineering rotor ring stoichiometries in the ATP synthase Denys Pogoryelov, Adriana L. Klyszejko, Ganna O. APPLIED MATHEMATICS Krasnoselska, Eva-Maria Heller, Vanessa Leone, 9699 Stochastic branching-diffusion models for Julian D. Langer, Janet Vonck, Daniel J. Müller, gene expression José D. Faraldo-Gómez, and Thomas Meier David Cottrell, Peter S. Swain, and Paul F. Tupper See full research article on page E1599 of www.pnas.org APPLIED PHYSICAL SCIENCES AND 9705 Weak electron–phonon coupling contributing to high 9678 Energetics of stalk intermediates in membrane fusion thermoelectric performance in n-type PbSe are controlled by lipid composition Heng Wang, Yanzhong Pei, Aaron D. LaLonde, Sebastian Aeffner, Tobias Reusch, Britta Weinhausen, and G. Jeffrey Snyder and Tim Salditt See full research article on page E1609 of www.pnas.org 9710 Interface control of bulk ferroelectric polarization P. Yu, W. Luo, D. Yi, J. X. Zhang, M. D. Rossell, C.-H. Yang, L. You, G. Singh-Bhalla, S. Y. Yang, Q. He, Q. M. Ramasse, DEVELOPMENTAL BIOLOGY R. Erni, L. W. Martin, Y. H. Chu, S. T. Pantelides, 9680 Functional roles of fructose S. J. Pennycook, and R. Ramesh Jinyoung Kim, Gwonhwa Song, Guoyao Wu, 9716 Elastic sheet on a liquid drop reveals wrinkling and and Fuller W. Bazer crumpling as distinct symmetry-breaking instabilities See full research article on page E1619 of www.pnas.org Hunter King, Robert D. Schroll, Benny Davidovitch, and Narayanan Menon MEDICAL SCIENCES 9822 Mosquitoes survive raindrop collisions by virtue – 9682 K-RAS GTPase- and B-RAF kinase mediated T-cell of their low mass tolerance defects in rheumatoid arthritis Andrew K. Dickerson, Peter G. Shankles, Karnail Singh, Pratima Deshpande, Guangjin Li, Mingcan Yu, Nihar M. Madhavan, and David L. Hu Sergey Pryshchep, Mary Cavanagh, Cornelia M. Weyand, and Jörg J. Goronzy 10036 Wet-surface–enhanced ellipsometric contrast See full research article on page E1629 of www.pnas.org microscopy identifies slime as a major adhesion factor during bacterial surface motility MICROBIOLOGY Adrien Ducret, Marie-Pierre Valignat, Fabrice Mouhamar, Tâm Mignot, and Olivier Theodoly 9684 Autophagy regulates Wolbachia populations across diverse symbiotic associations Denis Voronin, Darren A. N. Cook, Andrew Steven, CHEMISTRY and Mark J. Taylor 9721 Room temperature femtosecond X-ray diffraction of See full research article on page E1638 of www.pnas.org photosystem II microcrystals Jan Kern, Roberto Alonso-Mori, Julia Hellmich, Rosalie 9686 Coordinated phenotype switching with large-scale Tran, Johan Hattne, Hartawan Laksmono, Carina Glöckner, fl fl chromosome ip- op inversion observed in bacteria Nathaniel Echols, Raymond G. Sierra, Jonas Sellberg, Longzhu Cui, Hui-min Neoh, Akira Iwamoto, Benedikt Lassalle-Kaiser, Richard J. Gildea, Pieter Glatzel, and Keiichi Hiramatsu Ralf W. Grosse-Kunstleve, Matthew J. Latimer, Trevor A. See full research article on page E1647 of www.pnas.org McQueen, Dörte DiFiore, Alan R. Fry, Marc Messerschmidt, Alan Miahnahri, Donald W. Schafer, M. Marvin Seibert, NEUROSCIENCE Dimosthenis Sokaras, Tsu-Chien Weng, Petrus H. Zwart, 9688 Primary somatosensory cortex discriminates affective William E. White, Paul D. Adams, Michael J. Bogan, significance in social touch Sébastien Boutet, Garth J. Williams, Johannes Messinger, Valeria Gazzola, Michael L. Spezio, Joset A. Etzel, Fulvia Nicholas K. Sauter, Athina Zouni, Uwe Bergmann, Castelli, Ralph Adolphs, and Christian Keysers Junko Yano, and Vittal K. Yachandra See full research article on page E1657 of www.pnas.org 9727 Metalloenzyme-like catalyzed isomerizations of sugars 9690 Spike timing plays a key role in synapse elimination at by Lewis acid zeolites the neuromuscular junction Ricardo Bermejo-Deval, Rajeev S. Assary, Eranda Nikolla, Morgana Favero, Giuseppe Busetto, and Alberto Cangiano Manuel Moliner, Yuriy Román-Leshkov, Son-Jong Hwang, See full research article on page E1667 of www.pnas.org Arna Palsdottir, Dorothy Silverman, Raul F. Lobo, Larry A. Curtiss, and Mark E. Davis

3 9733 Intersystem crossing and dynamics in O( P) + C2H4 INAUGURAL ARTICLE multichannel reaction: Experiment validates theory Bina Fu, Yong-Chang Han, Joel M. Bowman, Luca Angelucci, Nadia Balucani, Francesca Leonori, 9692 Quantification of the relative roles of niche and neutral and Piergiorgio Casavecchia processes in structuring gastrointestinal microbiomes Patricio Jeraldo, Maksim Sipos, Nicholas Chia, Jennifer M. 9739 Reversible voltammograms and a Pourbaix diagram Brulc, A. Singh Dhillon, Michael E. Konkel, Charles L. for a protein tyrosine radical Larson, Karen E. Nelson, Ani Qu, Lawrence B. Schook, Bruce W. Berry, Melissa C. Martínez-Rivera, Fang Yang, Bryan A. White, and Nigel Goldenfeld and Cecilia Tommos

iv u www.pnas.org Downloaded by guest on September 27, 2021 9744 Water at hydrophobic interfaces delays proton 9923 Human origins and the transition from promiscuity surface-to-bulk transfer and provides a pathway to pair-bonding for lateral proton diffusion Sergey Gavrilets Chao Zhang, Denis G. Knyazev, Yana A. Vereshaga, Emiliano Ippoliti, Trung Hai Nguyen, Paolo Carloni, and Peter Pohl ECONOMIC SCIENCES ’ – 9828 Photochemically driven redox chemistry induces 9775 China s life satisfaction, 1990 2010 protocell membrane pearling and division Richard A. Easterlin, Robson Morgan, Malgorzata Switek, Ting F. Zhu, Katarzyna Adamala, Na Zhang, and Fei Wang and Jack W. Szostak See Commentary on page 9670 9917 Interaction of structure-specific and promiscuous G-protein–coupled receptors mediates small-molecule SOCIAL SCIENCES signaling in Caenorhabditis elegans 9929 Direct reciprocity in structured populations ’ Donha Park, Inish O Doherty, Rishi K. Somvanshi, Matthijs van Veelen, Julián García, David G. Rand, Axel Bethke, Frank C. Schroeder, Ujendra Kumar, and Martin A. Nowak and Donald L. Riddle

EARTH, ATMOSPHERIC, AND PLANETARY SCIENCES 9750 Differentiating biotic from abiotic methane genesis in BIOLOGICAL SCIENCES hydrothermally active planetary surfaces Christopher Oze, L. Camille Jones, Jonas I. Goldsmith, ANTHROPOLOGY and Robert J. Rosenbauer 9781 Religion as a means to assure paternity

9755 Mode change of millennial CO2 variability during the last Beverly I. Strassmann, Nikhil T. Kurapati, Brendan F. Hug, glacial cycle associated with a bipolar marine Erin E. Burke, Brenda W. Gillespie, Tatiana M. Karafet, carbon seesaw and Michael F. Hammer Bernhard Bereiter, Dieter Lüthi, Michael Siegrist, Simon Schüpbach, Thomas F. Stocker, and Hubertus Fischer APPLIED BIOLOGICAL SCIENCES 9989 Rapidly assessing changes in bone mineral balance using natural stable calcium isotopes 9786 Implanted adipose progenitor cells as physicochemical Jennifer L. L. Morgan, Joseph L. Skulan, Gwyneth W. regulators of breast cancer Gordon, Stephen J. Romaniello, Scott M. Smith, Emily M. Chandler, Bo Ri Seo, Joseph P. Califano, Roberto C. and Ariel D. Anbar Andresen Eguiluz, Jason S. Lee, Christine J. Yoon, David T. Tims, James X. Wang, Le Cheng, Sunish Mohanan, Mark R. Buckley, Itai Cohen, Alexander Yu Nikitin, Rebecca M. Williams, Delphine Gourdon, Cynthia A. Reinhart-King, 9761 Enabling single-mode behavior over large areas with and Claudia Fischbach photonic Dirac cones Jorge Bravo-Abad, John D. Joannopoulos, and Marin Soljacic BIOCHEMISTRY 9766 Semimetallic dense hydrogen above 260 GPa 9792 Dynamic flexibility of the ATPase p97 is important Sébastien Lebègue, Carlos Moyses Araujo, Duck Young Kim, for its interprotomer motion transmission Muhammad Ramzan, Ho-kwang Mao, and Rajeev Ahuja Chengdong Huang, Guangtao Li, and William J. Lennarz 9770 Digital atom interferometer with single particle control on a discretized space-time geometry 9798 Discovery of antimicrobial ribonucleotide reductase Andreas Steffen, Andrea Alberti, Wolfgang Alt, Noomen inhibitors by screening in microwell format Belmechri, Sebastian Hild, Michał Karski, Artur Widera, Fredrik Tholander and Britt-Marie Sjöberg and Dieter Meschede 9804 RecQ helicase translocates along single-stranded DNA 9833 Dislocation-mediated growth of bacterial cell walls with a moderate processivity and tight Ariel Amir and David R. Nelson mechanochemical coupling Kata Sarlós, Máté Gyimesi, and Mihály Kovács 9839 Biomimetic emulsions reveal the effect of mechanical forces on cell–cell adhesion 9810 Critical features for biosynthesis, stability, and Lea-Laetitia Pontani, Ivane Jorjadze, Virgile Viasnoff, functionality of a G protein-coupled receptor and Jasna Brujic uncovered by all-versus-all mutations Karola M. Schlinkmann, Annemarie Honegger, Esin Türeci, Keith E. Robison, DašaLipovšek, and Andreas Plückthun SOCIAL SCIENCES 9816 Low-resolution solution structures of Munc18:Syntaxin protein complexes indicate an open binding mode driven ANTHROPOLOGY by the Syntaxin N-peptide 9781 Religion as a means to assure paternity Michelle P. Christie, Andrew E. Whitten, Gordon J. King, Beverly I. Strassmann, Nikhil T. Kurapati, Brendan F. Hug, Shu-Hong Hu, Russell J. Jarrott, Kai-En Chen, Anthony P. Erin E. Burke, Brenda W. Gillespie, Tatiana M. Karafet, Duff, Philip Callow, Brett M. Collins, David E. James, and Michael F. Hammer and Jennifer L. Martin

PNAS u June 19, 2012 u vol. 109 u no. 25 u v Downloaded by guest on September 27, 2021 BIOPHYSICS AND COMPUTATIONAL BIOLOGY 9887 Molecular driving forces defining lipid positions 9721 Room temperature femtosecond X-ray diffraction of around aquaporin-0 photosystem II microcrystals Camilo Aponte-Santamaría, Rodolfo Briones, Andreas D. Jan Kern, Roberto Alonso-Mori, Julia Hellmich, Rosalie Schenk, Thomas Walz, and Bert L. de Groot Tran, Johan Hattne, Hartawan Laksmono, Carina Glöckner, Nathaniel Echols, Raymond G. Sierra, Jonas Sellberg, CELL BIOLOGY Benedikt Lassalle-Kaiser, Richard J. Gildea, Pieter Glatzel, fi Ralf W. Grosse-Kunstleve, Matthew J. Latimer, Trevor A. 9893 Probing isoform-speci c functions of polypeptide fi McQueen, Dörte DiFiore, Alan R. Fry, Marc Messerschmidt, GalNAc-transferases using zinc nger nuclease Alan Miahnahri, Donald W. Schafer, M. Marvin Seibert, glycoengineered SimpleCells Dimosthenis Sokaras, Tsu-Chien Weng, Petrus H. Zwart, Katrine T.-B. G. Schjoldager, Sergey Y. Vakhrushev, William E. White, Paul D. Adams, Michael J. Bogan, Yun Kong, Catharina Steentoft, Aaron S. Nudelman, Sébastien Boutet, Garth J. Williams, Johannes Messinger, Nis B. Pedersen, Hans H. Wandall, Ulla Mandel, Nicholas K. Sauter, Athina Zouni, Uwe Bergmann, Eric P. Bennett, Steven B. Levery, and Henrik Clausen Junko Yano, and Vittal K. Yachandra See Commentary on page 9672 9899 Multisite phosphoregulation of Cdc25 activity refines 9822 Mosquitoes survive raindrop collisions by virtue the mitotic entrance and exit switches of their low mass Lucy X. Lu, Maria Rosa Domingo-Sananes, Malwina Andrew K. Dickerson, Peter G. Shankles, Huzarska, Bela Novak, and Kathleen L. Gould Nihar M. Madhavan, and David L. Hu 9905 Rho GTP exchange factor ARHGEF11 regulates the 9828 Photochemically driven redox chemistry induces integrity of epithelial junctions by connecting protocell membrane pearling and division ZO-1 and RhoA-Myosin II signaling Ting F. Zhu, Katarzyna Adamala, Na Zhang, Masahiko Itoh, Sachiko Tsukita, Yuji Yamazaki, and Jack W. Szostak and Hiroyuki Sugimoto

9833 Dislocation-mediated growth of bacterial cell walls 9911 Induction of a G1-S checkpoint in fission yeast Ariel Amir and David R. Nelson Cathrine A. Bøe, Marit Krohn, Gro Elise Rødland, Christoph Capiaghi, Olivier Maillard, Fritz Thoma, Erik Boye, 9839 Biomimetic emulsions reveal the effect of mechanical and Beáta Grallert forces on cell–cell adhesion Lea-Laetitia Pontani, Ivane Jorjadze, Virgile Viasnoff, DEVELOPMENTAL BIOLOGY and Jasna Brujic 9917 Interaction of structure-specific and promiscuous 9845 Multiscale natural moves refine macromolecules using G-protein–coupled receptors mediates small-molecule single-particle electron microscopy projection images signaling in Caenorhabditis elegans Junjie Zhang, Peter Minary, and Michael Levitt Donha Park, Inish O’Doherty, Rishi K. Somvanshi, Axel Bethke, Frank C. Schroeder, Ujendra Kumar, 9851 Hydrophobic forces and the length limit of foldable and Donald L. Riddle protein domains Milo M. Lin and Ahmed H. Zewail ECOLOGY 9857 Structural engineering of a phage lysin that targets 9692 Quantification of the relative roles of niche and neutral Gram-negative pathogens processes in structuring gastrointestinal microbiomes Petra Lukacik, Travis J. Barnard, Paul W. Keller, Kaveri S. Patricio Jeraldo, Maksim Sipos, Nicholas Chia, Jennifer M. Chaturvedi, Nadir Seddiki, James W. Fairman, Nicholas Brulc, A. Singh Dhillon, Michael E. Konkel, Charles L. Noinaj, Tara L. Kirby, Jeffrey P. Henderson, Alasdair C. Larson, Karen E. Nelson, Ani Qu, Lawrence B. Schook, Steven, B. Joseph Hinnebusch, and Susan K. Buchanan Fang Yang, Bryan A. White, and Nigel Goldenfeld

9863 Capturing directed molecular motion in the nuclear pore complex of live cells EVOLUTION Francesco Cardarelli, Luca Lanzano, and Enrico Gratton 9923 Human origins and the transition from promiscuity to pair-bonding 9869 Chemotactic adaptation kinetics of individual Sergey Gavrilets Escherichia coli cells 9929 Direct reciprocity in structured populations Taejin L. Min, Patrick J. Mears, Ido Golding, and Yann R. Chemla Matthijs van Veelen, Julián García, David G. Rand, and Martin A. Nowak 9875 Accurate modeling using sparse NMR 9935 Specific inactivation of two immunomodulatory SIGLEC data and homologous structure information genes during human evolution James M. Thompson, Nikolaos G. Sgourakis, Gaohua Liu, Xiaoxia Wang, Nivedita Mitra, Ismael Secundino, Kalyan Paolo Rossi, Yuefeng Tang, Jeffrey L. Mills, Thomas Banda, Pedro Cruz, Vered Padler-Karavani, Andrea Szyperski, Gaetano T. Montelione, and David Baker Verhagen, Chris Reid, Martina Lari, Ermanno Rizzi, Carlotta Balsamo, Giorgio Corti, Gianluca De Bellis, Laura Longo, 9881 Cooperative coupling of cell-matrix and cell–cell NISC Comparative Sequencing Program, William Beggs, adhesions in cardiac muscle David Caramelli, Sarah A. Tishkoff, Toshiyuki Hayakawa, Megan L. McCain, Hyungsuk Lee, Yvonne Aratyn-Schaus, Eric D. Green, James C. Mullikin, Victor Nizet, Jack Bui, André G. Kléber, and Kevin Kit Parker and Ajit Varki

vi u www.pnas.org Downloaded by guest on September 27, 2021 GENETICS 10006 Spleen serves as a reservoir of osteoclast precursors 9941 Y chromosome mediates ribosomal DNA silencing and through vitamin D-induced IL-34 expression in modulates the chromatin state in Drosophila osteopetrotic op/op mice Jun Zhou, Timothy B. Sackton, Lene Martinsen, Bernardo Yuko Nakamichi, Toshihide Mizoguchi, Atsushi Arai, Lemos, Thomas H. Eickbush, and Daniel L. Hartl Yasuhiro Kobayashi, Masahiro Sato, Josef M. Penninger, Hisataka Yasuda, Shigeaki Kato, Hector F. DeLuca, Tatsuo 9947 Reciprocal uniparental disomy in yeast Suda, Nobuyuki Udagawa, and Naoyuki Takahashi Sabrina L. Andersen and Thomas D. Petes 10012 Bioinspired nanofibers support chondrogenesis for articular cartilage repair 9953 Cell cycle- and DNA repair pathway-specific effects of Jeannine M. Coburn, Matthew Gibson, Sean Monagle, apoptosis on tumor suppression Zachary Patterson, and Jennifer H. Elisseeff Steven S. Foster, Saurav De, Linda K. Johnson, John H. J. Petrini, and Travis H. Stracker 10018 Gaucher disease gene GBA functions in immune regulation Jun Liu, Stephanie Halene, Mei Yang, Jameel Iqbal, Ruhua IMMUNOLOGY Yang, Wajahat Z. Mehal, Wei-Lien Chuang, Dhanpat Jain, 9959 Drug hypersensitivity caused by alteration of the Tony Yuen, Li Sun, Mone Zaidi, and Pramod K. Mistry MHC-presented self-peptide repertoire 10024 Impaired function of the Tie-2 receptor contributes to David A. Ostrov, Barry J. Grant, Yuri A. Pompeu, John vascular leakage and lethality in anthrax Sidney, Mikkel Harndahl, Scott Southwood, Carla Oseroff, Chandra C. Ghosh, Aditi Mukherjee, Sascha David, Ulla G. Shun Lu, Jean Jakoncic, Cesar Augusto F. de Oliveira, Lun Knaus, Deborah J. Stearns-Kurosawa, Shinichiro Kurosawa, Yang, Hu Mei, Leming Shi, Jeffrey Shabanowitz, A. Michelle and Samir M. Parikh English, Amanda Wriston, Andrew Lucas, Elizabeth Phillips, Simon Mallal, Howard M. Grey, Alessandro Sette, Donald F. 10030 Force of infection is key to understanding the Hunt, Soren Buus, and Bjoern Peters epidemiology of Plasmodium falciparum malaria in Papua New Guinean children 9965 Temporal expression of microRNA cluster miR-17-92 fl + Ivo Mueller, Sonja Schoep in, Thomas A. Smith, Kathryn L. regulates effector and memory CD8 Benton, Michael T. Bretscher, Enmoore Lin, Benson T-cell differentiation Kiniboro, Peter A. Zimmerman, Terence P. Speed, Peter Siba, Tuoqi Wu, Andreas Wieland, Koichi Araki, Carl W. Davis, and Ingrid Felger Lilin Ye, J. Scott Hale, and Rafi Ahmed

9971 Regulation of innate CD8+ T-cell activation mediated MICROBIOLOGY by cytokines Bailey E. Freeman, Erika Hammarlund, Hans-Peter Raué, 10036 Wet-surface–enhanced ellipsometric contrast and Mark K. Slifka microscopy identifies slime as a major adhesion factor during bacterial surface motility 9977 Alternatively activated dendritic cells regulate CD4+ Adrien Ducret, Marie-Pierre Valignat, Fabrice Mouhamar, T-cell polarization in vitro and in vivo Tâm Mignot, and Olivier Theodoly Peter C. Cook, Lucy H. Jones, Stephen J. Jenkins, Thomas A. 10042 Microbial interspecies electron transfer via electric Wynn, Judith E. Allen, and Andrew S. MacDonald currents through conductive minerals 9983 Perforin-dependent CD4+ T-cell cytotoxicity contributes Souichiro Kato, Kazuhito Hashimoto, and Kazuya Watanabe to control a murine poxvirus infection 10047 Structure and regulon of Campylobacter jejuni ferric Min Fang, Nicholas A. Siciliano, Adam R. Hersperger, Felicia uptake regulator Fur define apo-Fur regulation Roscoe, Angela Hu, Xueying Ma, Ahamed R. Shamsedeen, James Butcher, Sabina Sarvan, Joseph S. Brunzelle, Laurence C. Eisenlohr, and Luis J. Sigal Jean-François Couture, and Alain Stintzi

10053 Pathogenesis of emerging severe fever with MEDICAL SCIENCES thrombocytopenia syndrome virus in C57/BL6 9989 Rapidly assessing changes in bone mineral balance using mouse model natural stable calcium isotopes Cong Jin, Mifang Liang, Junyu Ning, Wen Gu, Hong Jiang, Jennifer L. L. Morgan, Joseph L. Skulan, Gwyneth W. Wei Wu, Fushun Zhang, Chuan Li, Quanfu Zhang, Hua Zhu, Gordon, Stephen J. Romaniello, Scott M. Smith, Ting Chen, Ying Han, Weilun Zhang, Shuo Zhang, Qin Wang, and Ariel D. Anbar Lina Sun, Qinzhi Liu, Jiandong Li, Tao Wang, Qiang Wei, Shiwen Wang, Ying Deng, Chuan Qin, and Dexin Li 9995 Soluble epoxide hydrolase regulates hematopoietic 10059 Attachment of Chlamydia trachomatis L2 to host cells progenitor cell function via generation of requires sulfation fatty acid diols David M. Rosmarin, Jan E. Carette, Andrew J. Olive, Timo Frömel, Benno Jungblut, Jiong Hu, Caroline Trouvain, Michael N. Starnbach, Thijn R. Brummelkamp, Eduardo Barbosa-Sicard, Rüdiger Popp, Stefan Liebner, and Hidde L. Ploegh Stefanie Dimmeler, Bruce D. Hammock, and Ingrid Fleming

10001 Cold but not sympathomimetics activates human brown adipose tissue in vivo NEUROSCIENCE Aaron M. Cypess, Yih-Chieh Chen, Cathy Sze, Ke Wang, 10065 Joint control of Drosophila male courtship behavior by Jeffrey English, Onyee Chan, Ashley R. Holman, Ilan Tal, motion cues and activation of male-specific P1 neurons Matthew R. Palmer, Gerald M. Kolodny, and C. Ronald Kahn Yufeng Pan, Geoffrey W. Meissner, and Bruce S. Baker

PNAS u June 19, 2012 u vol. 109 u no. 25 u vii Downloaded by guest on September 27, 2021 10071 Loss of functional GABAA receptors in the Alzheimer 10107 Feedback regulation of plastidic acetyl-CoA carboxylase diseased brain by 18:1-acyl carrier protein in Brassica napus Agenor Limon, Jorge Mauricio Reyes-Ruiz, Carl Andre, Richard P. Haslam, and John Shanklin and Ricardo Miledi 10113 Tobacco calmodulin-like protein provides secondary 10077 Functional organization of the insula and inner defense by binding to and directing degradation perisylvian regions of virus RNA silencing suppressors Ahmad Jezzini, Fausto Caruana, Ivilin Stoianov, Kenji S. Nakahara, Chikara Masuta, Syouta Yamada, Hanako Vittorio Gallese, and Giacomo Rizzolatti Shimura, Yukiko Kashihara, Tomoko S. Wada, Ayano 10083 Dissociating activity in the lateral intraparietal area from Meguro, Kazunori Goto, Kazuki Tadamura, Kae Sueda, Toru value using a visual foraging task Sekiguchi, Jun Shao, Noriko Itchoda, Takeshi Matsumura, Koorosh Mirpour and James W. Bisley Manabu Igarashi, Kimihito Ito, Richard W. Carthew, and Ichiro Uyeda

PHYSIOLOGY 10119 Dual disease resistance mediated by the immune 10089 3′ Phosphatase activity toward phosphatidylinositol receptor Cf-2 in tomato requires a common virulence

3,4-bisphosphate [PI(3,4)P2] by voltage-sensing target of a fungus and a nematode phosphatase (VSP) Jose L. Lozano-Torres, Ruud H. P. Wilbers, Piotr Gawronski, Tatsuki Kurokawa, Shunsuke Takasuga, Souhei Sakata, Jordi C. Boshoven, Anna Finkers-Tomczak, Jan H. G. Shinji Yamaguchi, Shigeo Horie, Koichi J. Homma, Cordewener, Antoine H. P. America, Hein A. Overmars, Takehiko Sasaki, and Yasushi Okamura John W. Van ‘t Klooster, Lukasz Baranowski, Miroslaw Sobczak, Muhammad Ilyas, Renier A. L. van der Hoorn, 10095 Aldosterone-independent regulation of the epithelial Arjen Schots, Pierre J. G. M. de Wit, Jaap Bakker, + Na channel (ENaC) by vasopressin in Aska Goverse, and Geert Smant adrenalectomized mice Elena Mironova, Vladislav Bugaj, Karl P. Roos, Donald E. Kohan, and James D. Stockand SYSTEMS BIOLOGY 9699 Stochastic branching-diffusion models for PLANT BIOLOGY gene expression 10101 Casparian strip diffusion barrier in Arabidopsis is made David Cottrell, Peter S. Swain, and Paul F. Tupper of a lignin polymer without suberin Sadaf Naseer, Yuree Lee, Catherine Lapierre, Rochus Franke, Christiane Nawrath, and Niko Geldner ix Subscription Form

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