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Mexican Participation in the First Latin American Suborbital Mission ESAA

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Mexican Participation in the First Latin American Suborbital Mission ESAA “Mexican Participation in the First Latin American Suborbital Mission ESAA-01 Carrying Out on Board Experiments that Help in the Cure of Cancer and Mellitus Diabetes in the Latin Population” Jose Alberto Ramirez Aguilar., Ph.D. Head of the Aerospace Department – UAT-FI-UNAM *Angel L. Rodriguez M. PhD, **Erendira Nava G. M.D., ***Dulce C. Sanchez H., M.I. *CFATA-UNAM; **APEM; ***UAQ UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. OUTLINE 1. Latcosmos, Space Development Plan 2. Cancer, the second cause of death in Latin America 3. Mellitus Diabetes, Mortality in Mexico 4. Generalities of an Experiment 5. Final notes 1 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. (1) Latcosmos. Space Development Project 2 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. LATCOSMOS SPACE DEVELOPMENT PLAN In October 2017 the IAF GRULAC in partnership with the Ecuadorian space AgencyCUAL-EXA launched ES ELthe PROBLEMA?LATCOSMOS Space Development plan, one of the programs within the plan is the LATCOSMOS-C Human space Flight Program. 3 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. The goal of this program is to allow Latinamerican professionals to be trained as payload specialists and fly a suborbital space mission as crew membersCUALwith ESthe ELobjective PROBLEMA?of operate an experiment of science or an engineering test and expose it to up to 5 minutes of microgravity. 4 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. The crew will fly with a payload rack able to carry up to 20 experiments or technical demonstrators. Each Crewman will be given one payload slot to be assigned freely within universities or research institutions in his/her country. CUAL ES EL PROBLEMA? More information in the official site at www.latcosmos.org 5 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. The means of this program is to train a crew of 4 payload specialist and 1 mission commander using a shorter version of the Advanced Suborbital Astronaut Training Program (ASA/T) developed by EXA/GCTC (Gagarin Cosmonaut Training Center). Then fly a technical research mission in suborbital space reaching more than 100 kmCUALabove Earth’s ESsurface, EL onboardPROBLEMA?the Blue Origin’s New Shepard (NS) launch vehicle Later in 2018, the Colombian Space Agency – AEC signed an agreement to join the program and help finance it. 6 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Latinamericans in Space: How it works? CUAL ES EL PROBLEMA? 7 Name: Cdr. Ronnie Nader Name: Phd. Alberto Ramirez Name: Msc/MdS Jonna Ocampo Function: Mission Commander Function: Payload Specialist Function: Payload Specialist Agency: EXA Institution: UNAM Agency: EXA/ICC Country: Ecuador Country: Mexico Country: USA Name: Phd Cdt. Adolfo Chaves Name: Function: Payload Specialist Function: Payload Specialist Institution: TEC-CR Institution: AEC Country: Costa Rica Country: Colombia 8 2020 ESAA-01 Mission Crew Candidate Pre-Selection (2) Cancer, the Second Cause of Death in Latin America. 9 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Cancer is, today, the second cause of death in Latin America. • Breast and prostate cancer are the most common among Mexicans. • In Latin America the cancers that are most common are: those of breast, prostate, liver and stomach. 10 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Incidence and mortality due to different types of cancer in more developed and less developed regions. 11 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Estimates of the incidence of cancer in Peru New cases per year 12 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Mortality (Peru) Cancer is the third cause of death nationwide currently. In particular, breast and prostate cancer are the most common among Mexicans. 13 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. • Mortality from cancer in northern Mexico is the highest in the entire country. • Physicians associate this high index with harmful habits and diet. • High consumption of meat and junk food. 14 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Mortality (Peru) Cancer is the third cause of death nationwide currently. In particular, breast and prostate cancer are the most common among Mexicans. 15 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. (3) Mellitus diabetes. Mortality in Mexico 16 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Diabetes is the leading cause of death in Mexico. • Mexico is the second place in the world in incidence of diabetes only after the United States. "We still suffer the sicknesses of • Mexico is the number one underdevelopment, like infectious diseases and place in the world in cases of malnutrition, and at the same time we're facing the challenges of advanced nations like cancer, obesity. obesity, diseases of the heart and diabetes," 17 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Diabetes Mortality in Mexico Actually, obesity is a very serious health problem in many of the developed countries and also in Mexico and other countries of Latin America. 18 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Percentage of people with Mellitus diabetes in different states of Mexico. 19 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Nicaragua (Kydney Cancer) 20 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Microgravity is when things seem to be weightless. "Micro" means "very small“. NASA Knows Series. ESA, JAXA, NASA study microgravity, because the studies help show what happens to people and other things in space. Here, we want contribute.!! 21 (4) Generalities of an experiment 16 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. Experiment • The project consists of the synthesis of a hydrogel to obtain Doxorubicina release tests. • Synthesize a hydrogel to perform Doxorubicin release tests, this information that allows us to obtain the necessary parameters that are required to reach the phase of the mathematical model. Doxorubicin as an anticancer drug. • Determine the necessary dose that is required for a direct application of Doxorubicin with hydrogel and nanoparticles subjected with shock waves to the tumor. 22 Experiment It is sought to synthesize different polymerizations, varying the concentrations of the monomers and the initiator, this, with the aim of obtaining polymers with different characteristics. Doxorubicin (DOXO) is a cytostatic antibiotic of the anthracycline family, and is the most used for chemotherapy in patients who are in advanced cancer. 23 The tendency is to obtain polymeric materials capable of responding to environmental stimuli such as temperature, electric or magnetic field, light, pH, specific molecules or enzymes, among others, to ensure that they can release their load in a controlled manner. Among the polymers, the hydrogels have shown very good properties to be loaded with drugs, because they are biocompatible and have swelling properties in aqueous medium, among other characteristics of interest, which makes them a good option to be used in controlled release of medicines 24 Hydrogel. Hydrogels are three-dimensional hydrophilic polymer networks of flexible chains, and may be of natural or synthetic origin. Its hydrophilic property is due to groups such as hydroxyl (-OH), carboxyl (-COOH), amide (-CONH2) and sulfonic (SO3H), along the polymer chains. They are characterized by their extraordinary ability to absorb water and other liquids. These materials are obtained by simultaneous polymerization and crosslinking of one or more monomers. 25 (5) Final Notes 16 UN Expert Meeting on Human Space Technology- Vienna, Austria, 4~ 6 December 2018 Vienna International Centre (VIC) area, Vienna Austria. That´s One Small Step for Man One Giant Leap for Mankind” Neil Armstrong That´s One Great Step for Latin America, One Giant Inspiration for future generations of Latin American Children” LATCOSMOS PROGRAM 26 Reach for the Stars!!! THANKS FOR YOUR ATTENTION!! [email protected] 26.
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