Product Datasheet
Human Flt-3ligand ELISA Kit
Catalog No: #EK5145
Orders: [email protected] Description Support: [email protected]
Product Name Human Flt-3ligand ELISA Kit
Specificity Human
Crossing Reactivity There is no detectable cross-reactivity with other relevant proteins.
Immunogen Type sf21,T27-P185
Other Names Fms-related tyrosine kinase 3 ligand; Flt3 ligand; Flt3L; SL cytokine; FLT3LG;
Accession No. P49771
Cell Localization Isoform 1: Cell membrane; Single-pass type Imembrane protein.
Application Details
sensitivity:10pg mlDetect Range:15.6pg ml-1000pg mlsample_type:cell culture supernates serum and plasma(heparin EDTA
citrate).capture_antibody:monoclonal antibody from mousedetection_antibody:polyclonal antibody from goatgene_name:FLT3LGprotein_name:Fms-related
tyrosine kinase 3 ligandgene_full_name:Fms-related tyrosine kinase 3
ligandtissue_specificity:sequence_similarities:tmb_incubation:15-20minresearch_category:cardiovascular|angiogenesis|cytokines|immunology|innate immunity
Product Description
Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Flt-3ligand
Background
protein_function: Stimulates the proliferation of early hematopoieticcells by activating FLT3. Synergizes well with a number of othercolony stimulating factors and interleukins.Fms-related tyrosine kinase 3 ligand(FLT3LG), also known as Flt-3ligand or FL, is a protein which in humans is encoded by the FLT3LG gene. It is mapped to 19q13.3. Flt-3ligand is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor(SCF) and colony stimulating factor 1(CSF-1). In synergy with other growth factors, Flt-3ligand stimulates the proliferation and differentiation of various blood cell progenitors. Besides that, Flt-3ligand can control the development of Dendritic cells(DCs) and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts. Flt-3ligand also can enhance the response of stem and primitive progenitor cells to other growth factors to generate all myeloid lineages except erythroid cells.
Note: This product is for in vitro research use only and is not intended for use in humans or animals.
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