Product Datasheet Human Flt-3ligand ELISA Kit Catalog No: #EK5145 Orders: [email protected] Description Support: [email protected] Product Name Human Flt-3ligand ELISA Kit Specificity Human Crossing Reactivity There is no detectable cross-reactivity with other relevant proteins. Immunogen Type sf21,T27-P185 Other Names Fms-related tyrosine kinase 3 ligand; Flt3 ligand; Flt3L; SL cytokine; FLT3LG; Accession No. P49771 Cell Localization Isoform 1: Cell membrane; Single-pass type Imembrane protein. Application Details sensitivity:10pg mlDetect Range:15.6pg ml-1000pg mlsample_type:cell culture supernates serum and plasma(heparin EDTA citrate).capture_antibody:monoclonal antibody from mousedetection_antibody:polyclonal antibody from goatgene_name:FLT3LGprotein_name:Fms-related tyrosine kinase 3 ligandgene_full_name:Fms-related tyrosine kinase 3 ligandtissue_specificity:sequence_similarities:tmb_incubation:15-20minresearch_category:cardiovascular|angiogenesis|cytokines|immunology|innate immunity Product Description Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Flt-3ligand Background protein_function: Stimulates the proliferation of early hematopoieticcells by activating FLT3. Synergizes well with a number of othercolony stimulating factors and interleukins.Fms-related tyrosine kinase 3 ligand(FLT3LG), also known as Flt-3ligand or FL, is a protein which in humans is encoded by the FLT3LG gene. It is mapped to 19q13.3. Flt-3ligand is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor(SCF) and colony stimulating factor 1(CSF-1). In synergy with other growth factors, Flt-3ligand stimulates the proliferation and differentiation of various blood cell progenitors. Besides that, Flt-3ligand can control the development of Dendritic cells(DCs) and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts. Flt-3ligand also can enhance the response of stem and primitive progenitor cells to other growth factors to generate all myeloid lineages except erythroid cells. Note: This product is for in vitro research use only and is not intended for use in humans or animals. Address: 8400 Baltimore Ave., Suite 302, College Park, MD 20740, USA http://www.sabbiotech.com 1.