Supplemental Table S2: Multiplex analyte array panel assays and protein abbreviations Analyte name (gene symbol) Panel 1 Panel 2 sCD137 (TNFRSF9) = soluble Cluster of Differentiation antigen 137 (TNF Receptor Superfamily Member 9) ✔ sCD40L (CD40LG) = soluble Cluster of Differentiation antigen 40 Ligand ✔ EGF = Epidermal Growth Factor ✔ Eotaxin (CCL11) = eotaxin-1 (C-C Motif Chemokine Ligand 11) ✔ sFas (TNFRSF6) = soluble Fas Cell Surface Death Receptor (TNF Receptor Super Family member 6) ✔ sFasL (FASLG, TNFSF6) = soluble Fas Cell Surface Death Receptor Ligand (TNF Super Family member 6) ✔ FGF2 = Fibroblast Growth Factor 2 (basic FGF) ✔ Flt-3L (FLT3LG) = Fms-Related Tyrosine Kinase 3 Ligand ✔ Soluble fractalkine (sCX3CL1) = (C-X3-C Motif Chemokine Ligand 1) ✔ G-CSF (CSF3) = Granulocyte Colony Stimulating Factor (Colony Stimulating Factor 3) ✔ GM-CSF (CSF2) = Granulocyte-Macrophage Colony Stimulating Factor (Colony Stimulating Factor 2) ✔ ✔ Granzyme A (GZMA) ✔ Granzyme B (GZMB) ✔ GRO (CXCL1) = melanoma GROwth stimulating activity alpha (C-X-C Motif Chemokine Ligand 1) ✔ IFNα2 (IFNA2) = Interferon alpha 2 ✔ IFNγ (IFNG) = Interferon gamma ✔ ✔ IL-1α (IL1A) = Interleukin 1 alpha ✔ IL-1β (IL1B) = Interleukin 1 beta ✔ IL-1RA (IL1RN) = Interleukin 1 receptor antagonist ✔ IL-2 = Interleukin 2 ✔ ✔ IL-3 = Interleukin 3 ✔ IL-4 = Interleukin 4 ✔ ✔ IL-5 = Interleukin 5 ✔ ✔ IL-6 = Interleukin 6 ✔ ✔ IL-7 = Interleukin 7 ✔ IL-8 (CXCL8) = Interleukin 8 (C-X-C Motif Chemokine Ligand 8) ✔ IL-9 = Interleukin 9 ✔ IL-10 = Interleukin 10 ✔ ✔ IL-12p40 (IL-12B) = Interleukin 12 p40 subunit (Interleukin 12B) ✔ IL-12p70 = heterodimer containing Interleukin 12 p35 subunit (Interleukin 12A) and IL-12p40 subunit ✔ IL-13 = Interleukin 13 ✔ ✔ IL-15 = Interleukin 15 ✔ IL-17A = Interleukin 17A ✔ IP-10 (CXCL10) = 10 KDa Interferon Gamma-Induced Protein (C-X-C Motif Chemokine Ligand 10) ✔ MDC (CCL22) = Macrophage-Derived Chemokine (C-C Motif Chemokine Ligand 22) ✔ MCP-1 (CCL2) = Monocyte Chemotactic Protein 1 (C-C Motif Chemokine Ligand 2) ✔ MCP-3 (CCL7) = Monocyte Chemotactic Protein 3 (C-C Motif Chemokine Ligand 7) ✔ MIP-1α (CCL3) = Macrophage Inflammatory Protein 1-alpha (C-C Motif Chemokine Ligand 3) ✔ ✔ MIP-1β (CCL4) = Macrophage Inflammatory Protein 1-beta (C-C Motif Chemokine Ligand 4) ✔ ✔ PDGF-AA = dimer containing Platelet Derived Growth Factor Subunit A (PDGFA) ✔ PDGF-AB/BB = dimers containing Platelet Derived Growth Factor Subunit B (PDGFB) ✔ Perforin (PRF1) = (Perforin 1) ✔ RANTES (CCL5) = Regulated upon Activation and Normally T-cell-Expressed and presumably Secreted (C-C Motif ✔ Chemokine Ligand 5) TGFα (TGFA) = Transforming Growth Factor Alpha ✔ TNFα (TNF) = Tumor Necrosis Factor alpha ✔ ✔ TNFβ (LTA) = Tumor Necrosis Factor beta (lymphotoxin-alpha) ✔ VEGFA = Vascular Endothelial Growth Factor A ✔ Panel 1 = Cytokine/Chemokine Panel I (Millipore-Sigma Cat. No. HCYTMAG-60K-PX41) Panel 2 = Human CD8+ T-Cell Panel (Millipore-Sigma Cat. No. HCD8MAG15K17PMX)

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