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TRBA 464 Biologische Arbeitsstoffe in Risikogruppen
Ausgabe Juli 2013 Technische Regeln für Einstufung von Parasiten TRBA 464 Biologische Arbeitsstoffe in Risikogruppen Die Technischen Regeln für Biologische Arbeitsstoffe (TRBA) geben den Stand der Technik, Arbeitsmedizin und Arbeitshygiene sowie sonstige gesicherte wissenschaftliche Erkenntnisse für Tätigkeiten mit biologischen Arbeitsstoffen, einschließlich deren Einstufung, wieder. Sie werden vom Ausschuss für Biologische Arbeitsstoffe ermittelt bzw. angepasst und vom Bundesministerium für Arbeit und Soziales im Gemeinsamen Ministerialblatt bekannt gegeben. Die TRBA „Einstufung von Parasiten in Risikogruppen“ konkretisiert im Rahmen des Anwendungsbereichs die Anforderungen der Biostoffverordnung. Bei Einhaltung der Technischen Regeln kann der Arbeitgeber insoweit davon ausgehen, dass die entsprechenden Anforderungen der Verordnung erfüllt sind. Die Einstufungen der biologischen Arbeitsstoffe in Risikogruppen werden nach dem Stand der Wissenschaft vorgenommen; der Arbeitgeber hat die Einstufung zu beachten. Die vorliegende Technische Regel schreibt die Technische Regel „Einstufung von Parasiten in Risikogruppen“ (Stand Oktober 2002) fort und wurde unter Federführung des Fachbereichs „Rohstoffe und chemische Industrie“ in Anwendung des Kooperationsmodells (vgl. Leitlinienpapier1 zur Neuordnung des Vorschriften- und Regelwerks im Arbeitsschutz vom 31. August 2011) erarbeitet. Inhalt 1 Anwendungsbereich 2 Allgemeines 3 Liste der Einstufungen der Parasiten 3.1 Vorbemerkungen 3.2 Einstufung der Endoparasiten von Mensch und Haustieren (einschließlich -
Molecular Detection of Human Parasitic Pathogens
MOLECULAR DETECTION OF HUMAN PARASITIC PATHOGENS MOLECULAR DETECTION OF HUMAN PARASITIC PATHOGENS EDITED BY DONGYOU LIU Boca Raton London New York CRC Press is an imprint of the Taylor & Francis Group, an informa business CRC Press Taylor & Francis Group 6000 Broken Sound Parkway NW, Suite 300 Boca Raton, FL 33487-2742 © 2013 by Taylor & Francis Group, LLC CRC Press is an imprint of Taylor & Francis Group, an Informa business No claim to original U.S. Government works Version Date: 20120608 International Standard Book Number-13: 978-1-4398-1243-3 (eBook - PDF) This book contains information obtained from authentic and highly regarded sources. Reasonable efforts have been made to publish reliable data and information, but the author and publisher cannot assume responsibility for the validity of all materials or the consequences of their use. The authors and publishers have attempted to trace the copyright holders of all material reproduced in this publication and apologize to copyright holders if permission to publish in this form has not been obtained. If any copyright material has not been acknowledged please write and let us know so we may rectify in any future reprint. Except as permitted under U.S. Copyright Law, no part of this book may be reprinted, reproduced, transmitted, or utilized in any form by any electronic, mechanical, or other means, now known or hereafter invented, including photocopying, microfilming, and recording, or in any information storage or retrieval system, without written permission from the publishers. For permission to photocopy or use material electronically from this work, please access www.copyright.com (http://www.copyright.com/) or contact the Copyright Clearance Center, Inc. -
The Complete Mitochondrial Genome of Echinostoma Miyagawai
Infection, Genetics and Evolution 75 (2019) 103961 Contents lists available at ScienceDirect Infection, Genetics and Evolution journal homepage: www.elsevier.com/locate/meegid Research paper The complete mitochondrial genome of Echinostoma miyagawai: Comparisons with closely related species and phylogenetic implications T Ye Lia, Yang-Yuan Qiua, Min-Hao Zenga, Pei-Wen Diaoa, Qiao-Cheng Changa, Yuan Gaoa, ⁎ Yan Zhanga, Chun-Ren Wanga,b, a College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, PR China b College of Life Science and Biotechnology, Heilongjiang Bayi Agricultural University, Daqing, Heilongjiang Province 163319, PR China ARTICLE INFO ABSTRACT Keywords: Echinostoma miyagawai (Trematoda: Echinostomatidae) is a common parasite of poultry that also infects humans. Echinostoma miyagawai Es. miyagawai belongs to the “37 collar-spined” or “revolutum” group, which is very difficult to identify and Echinostomatidae classify based only on morphological characters. Molecular techniques can resolve this problem. The present Mitochondrial genome study, for the first time, determined, and presented the complete Es. miyagawai mitochondrial genome. A Comparative analysis comparative analysis of closely related species, and a reconstruction of Echinostomatidae phylogeny among the Phylogenetic analysis trematodes, is also presented. The Es. miyagawai mitochondrial genome is 14,416 bp in size, and contains 12 protein-coding genes (cox1–3, nad1–6, nad4L, cytb, and atp6), 22 transfer RNA genes (tRNAs), two ribosomal RNA genes (rRNAs), and one non-coding region (NCR). All Es. miyagawai genes are transcribed in the same direction, and gene arrangement in Es. miyagawai is identical to six other Echinostomatidae and Echinochasmidae species. The complete Es. miyagawai mitochondrial genome A + T content is 65.3%, and full- length, pair-wise nucleotide sequence identity between the six species within the two families range from 64.2–84.6%. -
Comparative Genomics of the Major Parasitic Worms
Comparative genomics of the major parasitic worms International Helminth Genomes Consortium Supplementary Information Introduction ............................................................................................................................... 4 Contributions from Consortium members ..................................................................................... 5 Methods .................................................................................................................................... 6 1 Sample collection and preparation ................................................................................................................. 6 2.1 Data production, Wellcome Trust Sanger Institute (WTSI) ........................................................................ 12 DNA template preparation and sequencing................................................................................................. 12 Genome assembly ........................................................................................................................................ 13 Assembly QC ................................................................................................................................................. 14 Gene prediction ............................................................................................................................................ 15 Contamination screening ............................................................................................................................ -
Resistant Pseudosuccinea Columella Snails to Fasciola Hepatica (Trematoda) Infection in Cuba : Ecological, Molecular and Phenotypical Aspects Annia Alba Menendez
Comparative biology of susceptible and naturally- resistant Pseudosuccinea columella snails to Fasciola hepatica (Trematoda) infection in Cuba : ecological, molecular and phenotypical aspects Annia Alba Menendez To cite this version: Annia Alba Menendez. Comparative biology of susceptible and naturally- resistant Pseudosuccinea columella snails to Fasciola hepatica (Trematoda) infection in Cuba : ecological, molecular and phe- notypical aspects. Parasitology. Université de Perpignan; Instituto Pedro Kouri (La Havane, Cuba), 2018. English. NNT : 2018PERP0055. tel-02133876 HAL Id: tel-02133876 https://tel.archives-ouvertes.fr/tel-02133876 Submitted on 20 May 2019 HAL is a multi-disciplinary open access L’archive ouverte pluridisciplinaire HAL, est archive for the deposit and dissemination of sci- destinée au dépôt et à la diffusion de documents entific research documents, whether they are pub- scientifiques de niveau recherche, publiés ou non, lished or not. The documents may come from émanant des établissements d’enseignement et de teaching and research institutions in France or recherche français ou étrangers, des laboratoires abroad, or from public or private research centers. publics ou privés. Délivré par UNIVERSITE DE PERPIGNAN VIA DOMITIA En co-tutelle avec Instituto “Pedro Kourí” de Medicina Tropical Préparée au sein de l’ED305 Energie Environnement Et des unités de recherche : IHPE UMR 5244 / Laboratorio de Malacología Spécialité : Biologie Présentée par Annia ALBA MENENDEZ Comparative biology of susceptible and naturally- resistant Pseudosuccinea columella snails to Fasciola hepatica (Trematoda) infection in Cuba: ecological, molecular and phenotypical aspects Soutenue le 12 décembre 2018 devant le jury composé de Mme. Christine COUSTAU, Rapporteur Directeur de Recherche CNRS, INRA Sophia Antipolis M. Philippe JARNE, Rapporteur Directeur de recherche CNRS, CEFE, Montpellier Mme. -
Anaphylaxis Caused by Helminths: Review of the Literature
European Review for Medical and Pharmacological Sciences 2012; 16: 1513-1518 Anaphylaxis caused by helminths: review of the literature P.L. MINCIULLO1, A. CASCIO2, A. DAVID3, L.M. PERNICE2, G. CALAPAI4, S. GANGEMI1,5 1School and Unit of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina, Italy 2Department of Human Pathology, University of Messina, Italy 3Department of Neurosciences, Psychiatric and Anesthesiological Sciences, University of Messina, Italy 4Department of Clinical and Experimental Medicine and Pharmacology, Section of Pharmacology, University of Messina, Italy 5Institute of Biomedicine and Molecular Immunology, National Research Council, Palermo, Italy Abstract. – BACKGROUND: Anaphylaxis is a Introduction severe, life-threatening, generalized or systemic hypersensitivity reaction. In many individuals Anaphylaxis is a severe, life-threatening, gen- with anaphylaxis a pivotal role is played by IgE and the high-affinity IgE receptor on mast cells eralized or systemic hypersensitivity reaction. or basophils. Less commonly, it is triggered The reaction usually develops gradually, most of- through other immunologic mechanisms, or ten starting with itching of the gums/throat, the through nonimmunologic mechanisms. The hu- palms, or the soles, and local urticaria; develop- man immune response to helminth infections ing to a multiple organ reaction often dominated is associated with elevated levels of IgE, tis- by severe asthma; and culminating in hypoten- sue eosinophilia and mastocytosis, and the 1 presence of CD4+ T cells that preferentially sion and shock . produce IL-4, IL-5, and IL-13. Individuals ex- In many individuals with anaphylaxis a pivotal posed to helminth infections may have allergic role is played by IgE and the high-affinity IgE re- inflammatory responses to parasites and para- ceptor on mast cells or basophils. -
Helminths and Helminthiasis
Methodenseminar Helminths and Helminthiasis I. Schabussova (SS 2014) Institute of Specific Prophylaxis and Tropical Medicine Medical University Vienna Introduction and overview • Parasites • Helminths • Developmental stages • Transmission • Life cycle • Localisation • Clinical presentation • Diagnosis • Treatment • Examples Parasite • CDC: A parasite is an organism that lives on • or in a host & gets its food from its host • Schmidt & Roberts (1985): "Parasites are those organisms studied by people who call themselves parasitologists“ • Latin: paras ītus - a person who lives by amusing the rich • Greek: paras ītos – a person who eats at someone else's table CDC: Centers for Disease Control and Prevention Parasite infestation & Parasitosis • Parasite infestation: presence of parasites in/on the host without clinical manifestation • Parasitosis: presence of parasites in/on the host with clinical manifestation (disease) Incubation period & Prepatent period • Incubation period: the period between the infection of an individual by a parasite and the manifestation of the disease it causes • • Prepatent period: the period between infection with a parasite and the demonstration of the parasite in the body - determined by the recovery of an infective form (oocysts, larvae, or eggs) from the blood, urine or feces; is usually shorter than the incubation period Host, Definitive host, Intermediate host & Reservoir • Host: is an organism that harbors a parasite, typically providing nutrition and shelter • Definitive host/primary host : is a host in which the parasite reaches maturity and, if possible, reproduces sexually • Intermediate host/a secondary host: is a host that harbors the parasite only for a short transition period, during which (usually) some developmental stage is completed • Reservoir host: can harbour a pathogen indefinitely with no ill effects. -
Schistosomatoidea and Diplostomoidea
See discussions, stats, and author profiles for this publication at: http://www.researchgate.net/publication/262931780 Schistosomatoidea and Diplostomoidea ARTICLE in ADVANCES IN EXPERIMENTAL MEDICINE AND BIOLOGY · JUNE 2014 Impact Factor: 1.96 · DOI: 10.1007/978-1-4939-0915-5_10 · Source: PubMed READS 57 3 AUTHORS, INCLUDING: Petr Horák Charles University in Prague 84 PUBLICATIONS 1,399 CITATIONS SEE PROFILE Libor Mikeš Charles University in Prague 14 PUBLICATIONS 47 CITATIONS SEE PROFILE Available from: Petr Horák Retrieved on: 06 November 2015 Chapter 10 Schistosomatoidea and Diplostomoidea Petr Horák , Libuše Kolářová , and Libor Mikeš 10.1 Introduction This chapter is focused on important nonhuman parasites of the order Diplostomida sensu Olson et al. [ 1 ]. Members of the superfamilies Schistosomatoidea (Schistosomatidae, Aporocotylidae, and Spirorchiidae) and Diplostomoidea (Diplostomidae and Strigeidae) will be characterized. All these fl ukes have indirect life cycles with cercariae having ability to penetrate body surfaces of vertebrate intermediate or defi nitive hosts. In some cases, invasions of accidental (noncompat- ible) vertebrate hosts (including humans) are also reported. Penetration of the host body and/or subsequent migration to the target tissues/organs frequently induce pathological changes in the tissues and, therefore, outbreaks of infections caused by these parasites in animal farming/breeding may lead to economical losses. 10.2 Schistosomatidae Members of the family Schistosomatidae are exceptional organisms among digenean trematodes: they are gonochoristic, with males and females mating in the blood vessels of defi nitive hosts. As for other trematodes, only some members of Didymozoidae are P. Horák (*) • L. Mikeš Department of Parasitology, Faculty of Science , Charles University in Prague , Viničná 7 , Prague 12844 , Czech Republic e-mail: [email protected]; [email protected] L. -
(12) United States Patent (10) Patent No.: US 8,377,639 B2 Ryder (45) Date of Patent: Feb
US008377639B2 (12) United States Patent (10) Patent No.: US 8,377,639 B2 Ryder (45) Date of Patent: Feb. 19, 2013 (54) COMPOUNDS FOR MODULATING RNA (56) References Cited BINDING PROTEINS AND USES THEREFOR |U.S. PATENT DOCUMENTS (75) Inventor: Sean Ryder, West Boylston, MA (US) 3,953,492 A * 4/1976 Mrozik ............................. 558/6 (73) Assignee: University of Massachusetts, Boston, FOREIGN PATENT DOCUMENTS WO WO86/03941 A1 7/1986 MA (US) WO WO02/083629 A1 10/2002 WO WO2004/046095 A1 6/2004 (*) Notice: Subject to any disclaimer, the term of this WO WO2006/110762 A2 10/2006 patent is extended or adjusted under 35 OTHER PUBLICATIONS U.S.C. 154(b) by 29 days. Massacret et al., Palladium(0)-Catalyzed Asymmetric Synthesis of (21) Appl. No.: 12/823,902 1,2,3,4-Tetrahydro-2-vinylquinoxalines, Eur, J. Org. Chem. 1999, 129-134.” Seftel et al., Comparison of Piperazine and Tetramisole in Treatment (22) Filed: Jun. 25, 2010 of Ascariasis, Brit. med. J., 1968, 4, 93-95.” International Search Report and Written Opinion issued in PCT/ (65) Prior Publication Data US2010/040035 on Jun. 29, 2011. |US 2011/0065704 A1 Mar 17, 2011 Mueller, Joachim et al., “Thioureides of 2-(phenoxymethyl)benzoic acid 4-R substituted: A novel class of anti-parasitic compounds”, Parasitology International, 2009, 58(2), pp. 128-135. (Available online Dec. 25, 2008). Related U.S. Application Data (60) Provisional application No. 61/220,985, filed on Jun. * cited by examiner 26, 2009. Primary Examiner – Jim Ketter Assistant Examiner – Reza Ghafoorian (51) Int. Cl. (74) Attorney, Agent, or Firm – McCarter & English, LLP; CI2O I/68 (2006.01) Elizabeth A. -
Tree Scale: 10
Tree scale: 10 Crassostrea virginica LOW QUALITY PROTEIN prospero homeobox protein 1-like XP 022331242.1 Crassostrea gigas PREDICTED prospero homeobox protein 1 isoform X2 XP 011452609.1 Lottia gigantea hypothetical protein LOTGIDRAFT 183824 XP 009063668.1 Mizuhopecten yessoensis prospero homeobox protein 1-like XP 021353659.1 Folsomia candida Homeobox protein prospero A0A226DDC5 Dinothrombium tinctorium Homeobox protein prospero-likePlatynereis dumerilii protein prospero A0A443RRV5 related homeodomain protein partial CAY12633.1 Tropilaelaps mercedesae Prospero domain-containing protein Fragment A0A1V9X985 Lingula anatina homeobox protein prospero isoform X1 XP 013407208.1 Capitella teleta prosperoAST23031.1 Malacoceros fuliginosus prox1 2015 C60118.0.T1 Doryteuthis pealeii prospero AOG30809.1 Leptochiton asellus prospero AMB26740.1 Penaeus vannamei Putative homeoboxTetranychus protein prosperourticae Prospero isoform domain-containing X2 A0A423SN37 protein T1JXP3 Ixodes scapularis Prospero protein putative B7Q1X0 Bombyx mori Prospero domain-containing protein H9J6E2Orchesella cincta Homeobox protein prospero A0A1D2MLK9 Operophtera brumata Homeobox protein prospero A0A0L7LJ21 025103990.1 XP PROTEIN uncharacterized protein LOC112570024 Pomacea canaliculata LOW QUALITY Aplysia californica PREDICTED alpha-protein kinase 1-like XP 012936323.1 Helobdella robusta hypothetical protein HELRODRAFT 79761 XP 009018226.1 Elysia chlorotica hypothetical protein EGW08 007276 RUS84965.1 Biomphalaria glabrata PREDICTED homeobox protein prospero homolog -
Trichobilharzia Mergi Sp. Nov. (Trematoda: Digenea: Schistosomatidae), a Visceral Schistosome of Mergus Serrator (L.) (Aves: Anatidae)
Parasitology International 62 (2013) 300–308 Contents lists available at SciVerse ScienceDirect Parasitology International journal homepage: www.elsevier.com/locate/parint Trichobilharzia mergi sp. nov. (Trematoda: Digenea: Schistosomatidae), a visceral schistosome of Mergus serrator (L.) (Aves: Anatidae) Libuše Kolářová a,b,⁎, Karl Skírnisson c, Hubert Ferté d, Damien Jouet d a Institute of Immunology and Microbiology, First Faculty of Medicine, Charles University in Prague, Czech Republic b General Hospital in Prague, Czech Republic c Institute for Experimental Pathology, University of Iceland, Keldur, Reykjavík, Iceland d EA 4688, USC-VECPAR, UFR de Pharmacie, Université de Reims Champagne-Ardenne, France article info abstract Article history: Parasitological investigations on red-breasted mergansers (Mergus serrator L.) in Iceland revealed digenean Received 16 September 2012 flukes of the family Schistosomatidae. Adult worms were detected in blood vessels of the large intestine and Received in revised form 6 February 2013 eggs were deposited in the mucosa and surrounded by granulomatous reactions. Traditional morphological Accepted 4 March 2013 methods showed that the flukes have very slender filiform bodies, males are equipped with a short Available online 13 March 2013 gynaecophoric canal and both suckers and spatulate ends are present on each sex. Among characteristics of the flukes which render them morphologically distinct from other Trichobilharzia species are: i) males—well Keywords: fi Trichobilharzia mergi sp. n. developed vesicula seminalis (v.s.) consisting of a short v.s. externa and a signi cantly longer (approx. 3 Description times) v.s. interna, unusually well developed genital papilla and localization of the first testis a relatively long Morphology distance posterior to the gynaecophoric canal; ii) eggs—small and elongated with slightly rounded poles and Sequence a short terminal spine. -
Masterarbeit / Master's Thesis
, MASTERARBEIT / MASTER’S THESIS Titel der Masterarbeit / Title of the Master‘s Thesis Digenean trematodes in freshwater snails in the surroundings of Vienna with a focus on species involved in human infections verfasst von / submitted by Nadine Hohensee BSc angestrebter akademischer Grad / in partial fulfilment of the requirements for the degree of Master of Science (MSc) Wien, 2016 / Vienna 2016 Studienkennzahl lt. Studienblatt / A 066 834 degree programme code as it appears on the student record sheet: Studienrichtung lt. Studienblatt / Masterstudium Molekulare Biologie degree programme as it appears on the student record sheet: Betreut von / Supervisor: Assoz. Prof. Univ.-Doz. Mag. Julia Walochnik, PhD Statutory Declaration I declare that I have authored this thesis independently, that I have not used other than the declared sources / resources and that I have explicitly marked all mate- rial which has been quoted either literally or by content from the used sources. …………………………… ……………………………………………….. Date Signature Index Index 1. Introduction ...................................................................................................................................... 1 1.1. Digenean Trematodes ....................................................................................................................... 1 1.1.1. Classification ............................................................................................................................... 1 1.1.2. Geographical Distribution .........................................................................................................