Andres Betts, M.D., D.A.B.P.M. Diplomat American Board of Pain Medicine and Anesthesiology

665 Camino del los Mares Suite 202 San Clemente, CA 92673 Ph: 949-364-8959 Fax: 949-218-1557 Mobile: 949-212-7172 E-mail: [email protected]

INTRODUCTION: Board Certified in Anesthesiology and Interventional Pain Management, specializing in the diagnosis and treatment of pain disorders, 25 years experience. National speaker, published author in peer-reviewed journals, newsletters, professional and general public articles. Physician instructor for Medical Device Industry, and Professional Organizations to train physicians in all aspects of interventional pain therapy techniques. Holder of six US PTSO issued patents defining new medical devices. Founder of Vertech, INC., a Medical Device development corporation VP Product Development Canal33, INC, a Medical Device development corporation. Surgical Case Review Chairman Saddleback Memorial Hospital to evaluate and review surgical complications. Expert Witness for Litigation and Defense.

Medical Practice: PainMD Medical Associates; Inc 665 Camino de los Mares, Suite 202 San Clemente, CA 92673 Ph: 949-364-8959 Ph: 949-212-7172 Fax: 949-218-1557 e-mail: [email protected] ESTABLISHED: June 24, 2003

Licensure and Certification:

California License- G055823 License- 27397 Federal DEA Number- BB0440090 Diplomate National Board of Medical Examiners American Board of Anesthesiology Certification April 1990 American Board of Pain Medicine Certification Feb 2000

Education:

University of California San Francisco School of Medicine 540 Parnassus Ave San Francisco, California 94143 Doctor of Medicine, June 1984

University of California San Diego 9500 Gilman Dr La Jolla, California 92093 Bachelor of Arts Biology, June 1979

Graduate Training:

Fellowship Critical Care Medicine Veterans Administration Medical Center Long Beach, California April – September 1988 Director David Wong, M.D.

Fellowship Obstetric Anesthesia University of California Irvine Medical Center/ Women’s Hospital Long Beach Memorial April- September 1987 Directors: H.J. Choi, M.D./Mohan Sidhu, M.D.

Residency in Anesthesiology University of California Irvine Medical Center 101 City Dr South Orange, California 92668 December 1985-November 1988 Chairman: Kevin K Tremper, Ph.D., M.D.

Internship in General Surgery University of California San Diego Medical Center 200 West Arbor Dr San Diego, California 92103 July 1984- June 1985 Chairman: A.R. Moossa , M.D.

Practice Experience:

PainMD Medical Associates, Inc President 665 Camino de los Mares, Suite 202 San Clemente, CA 92673 949-364-8959 June 03- present Full time solo practice specializing in interventional pain management, including epidural, transforaminal, selective nerve root, and facet joint injections of the cervical, thoracic and lumbar spine; sympathetic block, stellate ganglion block, sacro-iliac joint, trigger points, spine radiofrequency lesioning/neuromodulation, chemical neuroablation, Radiofrequency Lesioning Trigeminal Nerve, and Vertebroplasty/Kyphoplasty/Sacroplasty. Spinal Cord Stimulation and Neuromodulation. Ultrasound guided pain Injection procedures Expert witness for Litigation and Defense Physician instructor for interventional technique training and physician proctoring for Hospital Credentialing.

Director Pain Services San Clemente Community Hospital 654 Camino de los Mares San Clemente, CA 92673 Ph: 949-489-4587 Fax: 949-489-4687 9/2003- 2008

PainRx, Inc; P.S. President 1616 Cornwall Ave, Suite 205 Bellingham, WA St Joseph Hospital Hospital Based Interventional Pain Management Service Full spectrum of interventional pain procedures Average over 2000 procedures per year. June 1999 – June 2003

Bellingham Anesthesia Associates, Inc. Staff Anesthesiologist St Joseph Hospital Dept of Anesthesiology 2901 Squalicum Pkwy Bellingham, WA 98225 June 1990- April 2001

Anesthesia Medical Group, Inc Staff Anesthesiologist Riverside Community Hospital 4445 Magnolia Ave Riverside, California 92501 December 1988-May 1990

Medical Consulting, Teaching and Administrative Contributions:

Chairman Department of Anesthesiology St Joseph Hospital Bellingham, Washington 1993, 1994 Vice-chairman 1995, 1996

Anesthesia for the pregnant patient presenting for non- obstetric surgery. St Joseph Hospital Bellingham, WA Hospital Medical Practice Guidelines developed and approved 1995

Corporate Vice President Bellingham Anesthesia Associates 1050 Larrabee Ave Bellingham, WA 98226 1993-1996

Pain Management Credentials Criteria: JCAHCO Compliant- developed and approved for St Joseph Hospital Medical Staff, Bellingham, Washington, 2001 & updated 2003

Pain Management Credentials Criteria: JCAHCO Compliant- developed and approved for San Clemente Community Hospital, San Clemente, California 3/04. Including Vertebroplasty and Kyphoplasty

Saddleback Memorial Hospital Medical Executive Committee Member at Large 2011-2012 Chairman Surgical Case Review Committee 2010- present

American Society of Interventional Pain Physician Physician Member since 2001 Vertebroplasty/Kyphoplasty Cadaver Course Instructor MERI Institute Memphis, TN 2/16/2007 2/7/08 5/15/09 2/17/12 4/12/13 New Orleans, LA Ultrasound Guided pain course instructor 4/4/14 Las Vegas, NV Ultrasound Guided Pain course instructor 2/28/15

Society for Pain Practice Management Cadaver Course Instructor and Lecturer Cervical, Thoracic and Lumbar Spine Injection Technique, Radio Frequency Lesioning and Vertebroplasty/Kyphoplasty Scottsdale, AZ 3/18/2005 St Louis, MO 11/9/2005 Scottsdale, AZ 3/33/2006 Scottsdale, AZ 3/15/07 Phoenix, AZ 3/6/08 Phoenix, AZ 4/2/09 Phoenix, AZ 2/27/10 Las Vegas, NV 3/5/11 Kansas City, MO 11/4/11 Ultrasound Guided Interventional Course Instructor and Lecturer San Diego, CA 7/9/11 Kansas City, MO 11/4/11 Las Vegas, NV 3/3/12 Las Vegas, NV 2/28/13 San Diego, CA 8/16/13 Phoenix, AZ 11/8/13 Las Vegas, NV 2/28/14 San Diego, CA 7/17/14

Stryker Medical Cadaver Course Instructor for Vertebroplasty, Kyphoplasty and Radiofrequency Lesioning Consultant for new product development 2003-present Baldwin Park, CA Kyphoplasty proctoring 7/8/05 and 7/15/05 Phoenix, AZ Kyphoplasty Cadaver course 2/2/06 Carlsbad, CA Kyphoplasty proctoring 11/22/06 Whittier, CA Radiofrequency proctoring 1/19/07 and 5/4/07 Irvine, CA Kyphoplasty cadaver course 2/5/11 Los Angeles, CA Kyphoplasty cadaver course 5/22/10 Phoenix, AZ Kyphoplasty proctoring 5/22/11 University of Utah Medical Center Kyphoplasty proctoring 5/26/11 and 7/15/11 Temecula, CA Kyphoplasty proctoring 5/9/11 San Clemente, CA Kyphoplasty proctoring 5/16/11

Kyphon Medical Consultant for new product development Instructor and proctor for Vertebral Kyphoplasty And Sacral Kyphoplasty 2005- present

Cardinal Health/CareFusion Consultant for new product development Cadaver Course Instructor and proctoring for Vertebroplasty and Kyphoplasty 2005- present Newport Beach, CA Kyphoplasty cadaver course 3/31/2009

Medtronic Consultant new product development Cadaver Course Instructor and proctoring for Vertebral Augmentation (Arcuplasty)/Kyphoplasty 2007- present

Memorial Care Best Practice Team Committee for Peri-operative Services Develop evidence based best practice guidelines for delivery of safe and effective peri-operative care, for patients undergoing surgical procedures at the five Memorial Care Affiliated Hospitals. Director: Clyde Wesp, M.D. 2006- present

Memorial Care Political Action/Government Relations Team Physician Delegate May 25, 2006 April 2007 Meeting at State Capitol with California State Legislators for promotion of Physician Society and Hospital Alliance for healthcare delivery and information technologies. Peter J. Mackler Director: Government Relations and Policy

KOCE Television American Health Journal Public Broadcast Community education program featured physician discussing Interventional Pain Medicine. Aired in May 2006

Expert Witness Experience Experienced as Expert Witness in Anesthesia and Pain Specialty related trial cases. Given depositions and testified at various trials for both defense and plaintiff MEDICAL DEVICE DEVELOPMENT AND PATENTS:

Vertech, Inc Chairman and Founder Medical Device Design and Development “Bringing Ideas to Invention” 665 Camino del los Mares Suite 202 San Clemente, CA 92673 Ph: 949-364-8959 Fax: 949-218-1557 E-mail: [email protected] February 23, 2008 through November 1, 2014 a California S Corp

PATENT HOLDINGS: HIGH FREQUENCY EPIDURAL NEUROMODULATION CATHETER WITHOUT NEEDLE FOR EFFECTUATING RF TREATMENT. US Patent No: US 8,103,356 Issued Date: Jan 24, 2012

HIGH FREQUENCY EPIDURAL NEUROMODULATION CATHETER FOR EFFECTUATING RF TREATMENT IN SPINAL CANAL AND METHOD OF USING SAME. US Patent No: US 8,075,556 Issued Date: Dec 13, 2011

EXPANDABLE BLADE DEVICE FOR STABILIZING COMPRESSION FRACTURES. (plurality of blades) US Patent Application No: 11/836,731 ISSUED PATENT No: US 8,114,084 Issued Date: Feb 14, 2012

EXPANDABLE BLADE DEVICE FOR STABILIZING COMPRESSION FRACTURES. (At least one blade bending convexially) US Patent Application No: 12/025,629 ISSUED PATENT No: US 8206391 Issued Date: 6/26/2012

EXPANDABLE BLADE DEVICE FOR STABILIZING LONG BONE FRACTURES US Patent Application No: 11/836,72 ISUUED PATENT No: US 8,157, 804 Issued Date: 4/17/2012

BETTS OSTEOTOME US Patent Application No: 12/748,137 ISSUED PATENT No: US 8,480,675 Issued Date: 7/9/2013

CANAL33, INC. Medical Device Corporation VP Product Development 9/23/13 to present Seeking FDA approval and monetization of Spinal Fracture Kyphoplasty device and Spinal High Frequency Neuromodulation Catheter device derived from Vertech, INC. Patent Holdings

Research Experience:

Research Fellow University of California San Diego Medical Center Department of Cardio-Thoracic Surgery San Diego, California June 1985-November 1985 Director: Richard M. Peters, M.D.

Medical Student Research Fellowship University of California San Francisco Medical Center Department of Microbiology and Tumour Virology San Francisco, California June 1981- June 1982 Director: J. Michael Bishop, M.D.

Research Associate University of California San Francisco Laboratory of Radiobiology San Francisco, California July 1979-June 1980 Director: Harvey M. Patt, Ph.D.

Research Assistant Salk Institute Tumour Virology Laboratory La Jolla, California September 1977-June 1980 Director: Walter Echart, Ph.D.

Research Assistant Cancer Biology Research Laboratory Stanford University Stanford, California June- September 1977 Director: Henry S Kaplan, M.D.

Presentations:

Human Evolution “Natural selection and the African/non-African genetic dichotomy” Cold Spring Harbor Laboratories Cold Spring Harbor, New York Presentation of abstract at international conference on Human origins and evolution October 1999

Human Evolution “Mongoloid Origins Out of Africa” Cold Spring Harbor Laboratories Cold Spring Harbor, New York Presentation of abstract at international conference on Human origins and evolution April 1997

Western Anesthesia Resident Conference “Massive hemorrhage secondary to D.I.C. following cardio-pulmonary bypass successfully treated with Desmopressin Acetate and conjugated estrogen” Vancouver, British Columbia Presentation of Abstract May 1988

Western Medical Student Research Forum “Macrophages resistant to transformation when infected with Rous Sarcoma Virus produce high levels of src protein” Carmel, California Presentation of abstract February 1982

Lectures:

“Physiology of Jurassic Giants” St Joseph Hospital Medical Staff Bellingham, Washington November 1996

“Mongoloid Origins Out of Africa” Western Washington University Department of Asian Studies/Anthropology Guest Lecture Bellingham, Washington March 1998

“Genealogy of Human Origins” Whatcom County Medical Society Bellingham, Washington Guest Lecture September 1998

“Heterosexual Transmission of HIV” St Joseph Hospital Medical Staff Bellingham, Washington Guest Lecture (CME credit) January 2001

“Avalanche Safety and Awareness” Otolaryngology Winter Conference Chateau Whistler Resort, British Columbia, Guest Lecture, Feb 2000

“Survival Skills for Skiing and Snowboarding in Avalanche Country” Community Service Lecture Sportsman Chalet, Bellingham, Washington November 1999 & 2000

“What a Pain Specialist Can Offer Your Patients” San Clemente Community Hospital San Clemente, CA CME Lecture for Medical Staff 10/03

“Hidden Paradox of HIV Transmission” Saddleback Memorial Hospital San Clemente CME Lecture for Medical Staff 1/05

“New Frontiers in Pain Management” Saddleback Memorial Hospital Laguna Hills CME Lecture for Medical Staff March 05 South Coast Medical Center Laguna Beach, CA Feb 07

Publications: Betts, A. Vertebroplasty of the S1 Vertebrae Pain Physician 2009; 12:651-657

Betts, A. Sacral Vertebral Augmentation: Confirmation of Fluoroscopic Landmarks by Open Dissection. Pain Physician. 2008. Jan; 11(1): 57-65.

Betts, A. All Fluoroscopic Technique for Sacral Vertebroplasty. Pain Physician. 2005;8:417-420.

Betts, A. Combined Fluoroscopic and Nerve Stimulator Technique for Injection of the Piriformis Muscle. Pain Physician 2004, 7:279-281.

Betts A. Risk of HIV contact among males utilizing female sex workers: a quantitative model. In review

Betts A. Role of semen in the female-to-male transmission of HIV. Annals of Epidemiology, Feb 2001; 11(2):154-155

Betts A. Natural selection and the African/non-African Genetic Dichotomy. Abstracts: Human Evolution, Cold Spring Harbor Laboratories, April 1999:13

Betts A., Eggan J.R. Unilateral pulmonary edema with interscalene block. Anesthesiology 1998; 88(4): 1113- 1114

Betts A. Mongoloid origins out of Africa. Abstracts: Human Evolution, Cold Spring Harbor Laboratories, October 1997: 77.

Betkowsky A., Newman R., Ott R., Tremper K.K. Massive hemorrhage secondary to D.I.C. following cardio-pulmonary bypass successfully treated with Desmopressin Acetate and conjugated estrogen. Abstracts: 26th Annual Western Anesthesia Conference, May 1988

Betkowsky A., Bishop J.M., Opperman H. Macrophages resistant to transformation when infected with Rous Sarcoma Virus produce high levels of src protein. Clinical Research, Feb 1982; 30 (1): 68A

LETTERS:

FUNCTIONAL BASED GUIDELINES FOR THE EVALUATION AND TREATENT OF PAIN. Andres Betts, M.D., DABPM Physician SCOPE Sept –Dec 2012: 6-10. In Hospital opioid management and pain assessment strategies Saddleback Memorial Health System publication.

OSTEOPOROSIS: A SILENT YET CRIPPLING DISEASE. Andres Betts, M.D., DABPM Physician SCOPE Sumer 2014 Osteoporosis and the management of Vertebral Compression Fractures Saddleback Memorial Health System Publication.

Easing the Pain of a Pain Practice Start Up Andres Betts, M.D., DABPM. Business considerations for starting a private practice pain management service. Industry Letter for McKesson, Inc. 12/3/2007

Awards: Orange County Medical Association Award for Physician of Excellence Pain Management Selected from physician peers to be recognized for exceptional medical care and expertise in specialty field Featured in Orange Coast Magazine January 2006 January 2014

American Health Journal “Health on Demand” Channel Video segment selected for 2007/2008 season “Top Docs” selected for series for PBS

Interests:

Member Mt Baker Ski Patrol 1990-1996 Ski Patrol certified in avalanche rescue, mountaineering and high angle rescue. Ski Mountaineering and Guiding , WA; British Columbia and Alberta, Canada; Argentina and Chile South American Andes. Helicopter skied extensively throughout , British Columbia, Alberta Canada and South American Andes. France: Chamonix, Corchivel, Val Thorens, and Meribel Italy: Cormayeir, Argentina: Las Lenas and Bariloche Chile: Portillo and Valle Nevado Competitive Extreme Skiing: Ski Bowl Ski Area, Oregon Mt Baker Ski Area Washington Whistler/Blackcomb Ski Area, British Columbia, Canada

Experienced Mountain and Rock Climber Achieved level 5.11b. Multiple ascents throughout Western Cascades including Liberty Bell, Cutthroat peak, North Twin Sisters, Mt Erie, Mt Hood, Squamish, Skaha, Whistler Nordic Wall, Harrison Hot Springs.

San Jose State University JV Soccer Team 9/74-6/75 and development team for San Jose Earthquakes Professional Soccer Team prior to Major League Soccer (MLS). Semi-Pro Soccer San Francisco League 6/75- 10/75. Club Soccer League Champions Fremont Stars 8/1976.

Also enjoy surfing, wake-boarding, mountain biking.

Auto Racing: Sports Car Club of America Licensed Driver For Lotus and AC Cobra Replica race cars. Mario Andretti INDY car racing California Super Speedway, tracking at 150.7 mph April 2014. Allen Berg Racing Open Wheel Formula cars California Super Speedway August 2014.

Guitarist- electric, acoustic and classical. Played professionally in various bands.

Paleo-Anthropology and Physical Anthropology- studied independently and participated in several international conferences.

Cosmology and Astrophysics- completed one-year postgraduate course in Astronomy and Astrophysics Western Washington University Bellingham, Washington 1999-2000. Instructor: Richard Vawter, Ph.D.

Memberships: American Society of Interventional Pain Physicians California Society of Interventional Pain Physicians Washington Society of Interventional Pain Physicians American Academy of Pain Medicine American Society of Anesthesiologists American Association for the Advancement of Science U.C. San Francisco School of Medicine Alumni U.C. San Diego Alumni

Personal:

Married to Robin Betts, Son, Aidan, born 6/11/05 Son, Ryan, born 12/2/1977 Member of US Navy SEAL Team One and Instructor

Born September 27, 1956 in Santiago, Chile Immigrated to the San Francisco Bay Area at age of two, Shortened my last name from Betkowsky to Betts after going into private practice- for patient convenience. Fluent in Spanish.