MDFI Rabbit Polyclonal Antibody – AP21195PU-N | Origene

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MDFI Rabbit Polyclonal Antibody – AP21195PU-N | Origene

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for AP21195PU-N MDFI Rabbit Polyclonal Antibody Product data: Product Type: Primary Antibodies Applications: WB Recommended Dilution: Western blot: 1/500 - 1/1000. Reactivity: Human, Mouse Host: Rabbit Clonality: Polyclonal Specificity: This antibody detects endogenous levels of MDFI protein. (region surrounding Pro134) Formulation: Phosphate buffered saline (PBS), pH 7.2 State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide Concentration: 1.0 mg/ml Purification: Affinity chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE) Conjugation: Unconjugated Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. Stability: Shelf life: one year from despatch. Predicted Protein Size: ~ 25 kDa Gene Name: Homo sapiens MyoD family inhibitor (MDFI), transcript variant 3 Database Link: Entrez Gene 17240 MouseEntrez Gene 4188 Human Q99750 Background: MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures. MDFI an also interfere with the DNA-binding activity of Myod family members and plays an important role in trophoblast and chondrogenic differentiation. This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 2 MDFI Rabbit Polyclonal Antibody – AP21195PU-N Synonyms: MyoD family inhibitor Protein Families: Transcription Factors Product images: Western blot (WB) analysis of MDFI antibody (Cat.-No.: AP21195PU-N) in extracts from Jurkat cells. This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 2.

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