Human CDK16 / PCTK1 (158-496, His-Tag) - Purified

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AR51243PU-N Human CDK16 / PCTK1 (158-496, His-tag) - Purified

Alternate names: Cell division protein kinase 16, Cyclin-dependent kinase 16, PCTAIRE 1, PCTAIRE-1, PCTAIRE-motif protein kinase 1, PCTAIRE1, Serine/threonine-protein kinase PCTAIRE-1 Quantity: 0.5 mg Concentration: 1.0 mg/ml (determined by Bradford assay) Background: Cyclin-dependent kinase 16 isoform 1, also known as CDK16, belong to the CDK family of serine/threonine protein kinases. These proteins have a core kinase domain flanked by unique amino- and carboxy-terminal domains. CDK proteins are known to regulate the cell cycle. CDK16, which is expressed primarily in mammalian brain, interacts with a variety of proteins, and is thought to be part of a multiple signal transduction cascade. Uniprot ID: Q00536 NCBI: NP_006192 GeneID: 5127 Species: Human Source: E. coli Format: State: Liquid purified protein Purity: >95% by SDS - PAGE Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol Description: Recombinant human CDK16 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSGFGKLET YIKLDKLGEG TYATVYKGKS KLTDNLVALK EIRLEHEEGA PCTAIREVSL LKDLKHANIV TLHDIIHTEK SLTLVFEYLD KDLKQYLDDC GNIINMHNVK LFLFQLLRGL AYCHRQKVLH RDLKPQNLLI NERGELKLAD FGLARAKSIP TKTYSNEVVT LWYRPPDILL GSTDYSTQID MWGVGCIFYE MATGRPLFPG STVEEQLHFI FRILGTPTEE TWPGILSNEE FKTYNYPKYR AEALLSHAPR LDSDGADLLT KLLQFEGRNR ISAEDAMKHP FFLSLGERIH KLPDTTSIFA LKEIQLQKEA SLRSSSMPDS GRPAFRVVDT EF Molecular weight: 41.1 kDa (362aa) confirmed by MALDI-TOF Storage: Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. Shelf life: one year from despatch. General Readings: Cheng K., et al. (2002) J Biol Chem. 277:31988-31993. Meyerson M., et al. (1992) EMBO J. 118:2909-2917.

For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20130426 1 / 2 AR51243PU-N: Human CDK16 / PCTK1 (158-496, His-tag) - Purified

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For research and in vitro use only. Not for diagnostic or therapeutic work. Material Safety Datasheets are available at www.acris-antibodies.com or on request. MP/20130426 2 / 2