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Cigarette Smoke Extract-Induced Adipogenesis in Graves' Orbital
J S YOON, H J LEE and others Treatment of GO by quercetin, 216:2 145–156 Research an antioxidant Cigarette smoke extract-induced adipogenesis in Graves’ orbital fibroblasts is inhibited by quercetin via reduction in oxidative stress Jin Sook Yoon*, Hyun Jung Lee1,*, Min Kyung Chae, Sang Yeul Lee and Eun Jig Lee1,2,† Departments of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea 1Endocrinology, Brain Korea 21 Project for Medical Science, Institute of Endocrine Research, and Severance Integrative Research Institute for Cerebral and Cardiovascular Disease, Seoul, Korea 2Biochemistry and Molecular Biology, Yonsei University College of Medicine, Seoul, Korea Correspondence *(J S Yoon and H J Lee contributed equally to this work) should be addressed to E J Lee †(E J Lee who is now at Department of Endocrinology, Yonsei University College of Medicine, 50 Yonsei-Ro, Email Seodaemun-Gu, Seoul 120-752, Korea) [email protected] Abstract Cigarette smoking is known to aggravate Graves’ orbitopathy (GO) severity by enhancing Key Words adipogenesis. We investigated the effect of quercetin, an antioxidant, on adipocyte " quercetin differentiation induced by cigarette smoke extract (CSE) in primary cultured orbital " Graves’ orbitopathy fibroblasts (OFs) from GO patients. Freshly prepared CSE was added to the cells and H2O2 was " heme oxygenase-1 used as a positive control. Intracellular reactive oxygen species (ROS) generation and " cigarette smoke extract Journal of Endocrinology adipogenesis were measured. The expressions of proteins peroxisome proliferator-activated " orbital fibroblasts receptor (PPAR) g, CCAAT-enhancer-binding proteins (C/EBP) a and b, and heme oxygenase-1 " adipogenesis (HO-1), an antioxidant enzyme, were examined during adipogenic differentiation. -
Great Britain, the Two World Wars and the Problem of Narrative
View metadata, citation and similar papers at core.ac.uk brought to you by CORE The Historical Journal provided by Apollo Great Br itain, the Two World Wars and the Problem of Narrative Journal: The Historical Journal Manuscript ID HJ-2016-005.R2 Manuscript Type: Article Period: 1900-99, 2000- Thematic: International Relations, Military, Cultural, Intellectual Geographic: Britain, Europe, Continental Cambridge University Press Page 1 of 60 The Historical Journal Britain, the Two World Wars and the Problem of Narrative BRITAIN, THE TWO WORLD WARS AND THE PROBLEM OF NARRATIVE: PUBLIC MEMORY, NATIONAL HISTORY AND EUROPEAN IDENTITY* David Reynolds Christ’s College, Cambridge So-called ‘memory booms’ have become a feature of public history, as well as providing golden opportunities for the heritage industry. Yet they also open up large and revealing issues for professional historians, shedding light on how societies conceptualize and understand their pasts.1 This article explores the way that British public discourse has grappled with the First and Second World Wars. At the heart of the British problem with these two defining conflicts of the twentieth century is an inability to construct a positive, teleological metanarrative of their overall ‘meaning’. By exploring this theme through historiography and memorialization, it is possible not merely to illuminate Britain’s self-understanding of its twentieth-century history, but also to shed light on the country’s contorted relationship with ‘Europe’, evident in party politics and public debate right down to the ‘Brexit’ referendum of 2016. The concept of mastering the past ( Vergangenheitsbewältigung ) originated in post-1945 West Germany as that country tried to address the horrendous legacies of Nazism. -
Aardman in Archive Exploring Digital Archival Research Through a History of Aardman Animations
Aardman in Archive Exploring Digital Archival Research through a History of Aardman Animations Rebecca Adrian Aardman in Archive | Exploring Digital Archival Research through a History of Aardman Animations Rebecca Adrian Aardman in Archive: Exploring Digital Archival Research through a History of Aardman Animations Copyright © 2018 by Rebecca Adrian All rights reserved. Cover image: BTS19_rgb - TM &2005 DreamWorks Animation SKG and TM Aardman Animations Ltd. A thesis submitted in partial fulfilment of the requirements for the degree of Master of Arts in Media and Performance Studies at Utrecht University. Author Rebecca A. E. E. Adrian Student number 4117379 Thesis supervisor Judith Keilbach Second reader Frank Kessler Date 17 August 2018 Contents Acknowledgements vi Abstract vii Introduction 1 1 // Stop-Motion Animation and Aardman 4 1.1 | Lack of Histories of Stop-Motion Animation and Aardman 4 1.2 | Marketing, Glocalisation and the Success of Aardman 7 1.3 | The Influence of the British Television Landscape 10 2 // Digital Archival Research 12 2.1 | Digital Surrogates in Archival Research 12 2.2 | Authenticity versus Accessibility 13 2.3 | Expanded Excavation and Search Limitations 14 2.4 | Prestige of Substance or Form 14 2.5 | Critical Engagement 15 3 // A History of Aardman in the British Television Landscape 18 3.1 | Aardman’s Origins and Children’s TV in the 1970s 18 3.1.1 | A Changing Attitude towards Television 19 3.2 | Animated Shorts and Channel 4 in the 1980s 20 3.2.1 | Broadcasting Act 1980 20 3.2.2 | Aardman and Channel -
Annual Report and Accounts 2004/2005
THE BFI PRESENTSANNUAL REPORT AND ACCOUNTS 2004/2005 WWW.BFI.ORG.UK The bfi annual report 2004-2005 2 The British Film Institute at a glance 4 Director’s foreword 9 The bfi’s cultural commitment 13 Governors’ report 13 – 20 Reaching out (13) What you saw (13) Big screen, little screen (14) bfi online (14) Working with our partners (15) Where you saw it (16) Big, bigger, biggest (16) Accessibility (18) Festivals (19) Looking forward: Aims for 2005–2006 Reaching out 22 – 25 Looking after the past to enrich the future (24) Consciousness raising (25) Looking forward: Aims for 2005–2006 Film and TV heritage 26 – 27 Archive Spectacular The Mitchell & Kenyon Collection 28 – 31 Lifelong learning (30) Best practice (30) bfi National Library (30) Sight & Sound (31) bfi Publishing (31) Looking forward: Aims for 2005–2006 Lifelong learning 32 – 35 About the bfi (33) Summary of legal objectives (33) Partnerships and collaborations 36 – 42 How the bfi is governed (37) Governors (37/38) Methods of appointment (39) Organisational structure (40) Statement of Governors’ responsibilities (41) bfi Executive (42) Risk management statement 43 – 54 Financial review (44) Statement of financial activities (45) Consolidated and charity balance sheets (46) Consolidated cash flow statement (47) Reference details (52) Independent auditors’ report 55 – 74 Appendices The bfi annual report 2004-2005 The bfi annual report 2004-2005 The British Film Institute at a glance What we do How we did: The British Film .4 million Up 46% People saw a film distributed Visits to -
HGTV's Alison Victoria
Summer 2015 HGTV’s Alison Victoria crashing kitchens, saving lives Protect Your Pet The Next Step to Avoid these common a No Kill Chicago household risks Englewood door-to-door outreach North Shore Adoption Center Opens! ABOUT If we could, we’d give it a thumbs up. FREDRICK - Adopted May 2015 CLOVER - Adopted May 2015 PAWS CHICAGO MISSION IS TO BUILD NO KILL COMMUNITIES – STARTING WITH A NO KILL CHICAGO – WHERE PETS ARE NO LONGER DESTROYED JUST BECAUSE THEY ARE HOMELESS. Since our founding in 1997, a year in which a staggering 42,561 dogs and cats were killed in Chicago, the number of homeless dogs and cats euthanized annually has dropped significantly, down 77 percent by 2014. But this drop does not mean our work is done: In 2014, 9,817 animals were still killed in Chicago and nearly 60,000 animals were killed in the state of Illinois. When will Chicago be considered a No Kill city? When we are saving every healthy and treatable animal. To reach that goal, PAWS Chicago is implementing a comprehensive No Kill model to build a No Kill Chicago. COMMUNITY ENGAGEMENT HEALTH & BEHAVIOR Community is at the core of everything we do. Engaging the public Part of the commitment to guaranteeing life for all PAWS pets is in the cause of homeless animals and providing them with the keeping them happy, healthy and continually moving toward new information to make lifesaving choices, like adoption and spay/neuter, loving homes. In order to achieve this goal, we have built a is what has brought about such transformation in our 17 years. -
World War I: the War to End All Wars and the Birth of a Handicapped International Criminal Justice System
Denver Journal of International Law & Policy Volume 30 Number 3 Summer Article 3 May 2020 World War I: The War to End All Wars and the Birth of a Handicapped International Criminal Justice System M. Cherif Bassiouni Follow this and additional works at: https://digitalcommons.du.edu/djilp Recommended Citation M. Cherif Bassiouni, World War I: The War to End All Wars and the Birth of a Handicapped International Criminal Justice System, 30 Denv. J. Int'l L. & Pol'y 244 (2002). This Article is brought to you for free and open access by Digital Commons @ DU. It has been accepted for inclusion in Denver Journal of International Law & Policy by an authorized editor of Digital Commons @ DU. For more information, please contact [email protected],[email protected]. WORLD WAR I: "THE WAR TO END ALL WARS"AND THE BIRTH OF A HANDICAPPED INTERNATIONAL CRIMINAL JUSTICE SYSTEM M. CHERIF BASSIOUNI* "Strategy is a system of stop-gaps." -Moltke' INTRODUCTION The words of Von Moltke, Germany's well-known general, are an apt prelude to the strategy of justice pursued by the Allies after World War I. It was, indeed, a "system of stop-gaps." World War I, commonly referred to as the "Great War" and "the war to end all wars," took place between 1914 and 1918 and "was the first general war, involving all the Great Powers of the day, to be fought out in the modem, industrialized world."2 The trigger for the war was an incident that occurred in the volatile Balkans 3 on June 28, 1914, in which Archduke Franz Ferdinand and his wife were assassinated by Gavrilo Princip as they rode in a car in Sarajevo.4 The " Professor of Law, President, International Human Rights Law Institute, DePaul University College of Law; President, International Association of Penal Law; President, International Institute for Higher Studies in Criminal Sciences. -
This Copy of the Thesis Has Been Supplied on Condition That Anyone Who
University of Plymouth PEARL https://pearl.plymouth.ac.uk 04 University of Plymouth Research Theses 01 Research Theses Main Collection 2014 The British Way of War in North West Europe 1944-45: A Study of Two Infantry Divisions Devine, Louis Paul http://hdl.handle.net/10026.1/3014 Plymouth University All content in PEARL is protected by copyright law. Author manuscripts are made available in accordance with publisher policies. Please cite only the published version using the details provided on the item record or document. In the absence of an open licence (e.g. Creative Commons), permissions for further reuse of content should be sought from the publisher or author. This copy of the thesis has been supplied on condition that anyone who consults it is understood to recognise that its copyright rests with its author and that no quotation from the thesis and no information derived from it may be published without the author's prior consent. 1 THE BRITISH WAY OF WAR IN NORTH WEST EUROPE 1944-45: A STUDY OF TWO INFANTRY DIVISIONS By LOUIS PAUL DEVINE A thesis Submitted to Plymouth University in partial fulfilment for the degree of DOCTOR OF PHILOSOPHY School of Humanities May 2013 2 Louis Paul Devine The British Way of War in North West Europe 1944-45: A Study of two infantry divisions Abstract This thesis will examine the British way of war as experienced by two British Infantry Divisions - the 43rd ‘Wessex’ and 53rd ‘Welsh’ - during the Overlord campaign in North West Europe in 1944 and 1945. The main locus of research centres on the fighting components of those divisions; the infantry battalions and their supporting regiments. -
Fiscal Year 2003 Agency Financial Report
Report on Performance and Accountability Table of Contents 4 Management Discussion & Analysis 5 Secretary’s Message 8 Mission, Vision and Organization 9 Executive Summary 24 Annual Performance Report 25 Strategic Goal 1: A Prepared Workforce 27 Outcome Goal 1.1 – Increase Employment, Earnings, and Assistance 49 Outcome Goal 1.2 – Increase the Number of Youth Making A Successful Transition to Work 61 Outcome Goal 1.3 – Improve the Effectiveness of Information and Analysis On The U.S. Economy 69 Strategic Goal 2: A Secure Workforce 71 Outcome Goal 2.1 – Increase Compliance With Worker Protection Laws 81 Outcome Goal 2.2 – Protect Worker Benefits 99 Outcome Goal 2.3 – Increase Employment and Earnings for Retrained Workers 107 Strategic Goal 3: Quality Workplaces 109 Outcome Goal 3.1 – Reduce Workplace Injuries, Illnesses, and Fatalities 127 Outcome Goal 3.2 – Foster Equal Opportunity Workplaces 135 Outcome Goal 3.3 – Reduce Exploitation of Child Labor and Address Core International Labor Standards Issues 143 Departmental Management Goals 145 Outcome Goal HR – Establish DOL as a Model Workplace 153 Outcome Goal PR – Improve Procurement Management 158 Outcome Goal FM – Enhance Financial Performance through Improved Accountability 163 Outcome Goal IT – Provide Better and More Secure Service to Citizens, Businesses, Government, and DOL Employees to Improve Mission Performance 168 Financial Performance Report 169 Chief Financial Officer’s Letter 171 Management of DOL’s Financial Resources 171 Chief Financial Officers Act (CFOA) 172 Inspector General -
Copyright by John Michael Meyer 2020
Copyright by John Michael Meyer 2020 The Dissertation Committee for John Michael Meyer Certifies that this is the approved version of the following Dissertation. One Way to Live: Orde Wingate and the Adoption of ‘Special Forces’ Tactics and Strategies (1903-1944) Committee: Ami Pedahzur, Supervisor Zoltan D. Barany David M. Buss William Roger Louis Thomas G. Palaima Paul B. Woodruff One Way to Live: Orde Wingate and the Adoption of ‘Special Forces’ Tactics and Strategies (1903-1944) by John Michael Meyer Dissertation Presented to the Faculty of the Graduate School of The University of Texas at Austin in Partial Fulfillment of the Requirements for the Degree of Doctor of Philosophy The University of Texas at Austin May 2020 Dedication To Ami Pedahzur and Wm. Roger Louis who guided me on this endeavor from start to finish and To Lorna Paterson Wingate Smith. Acknowledgements Ami Pedahzur and Wm. Roger Louis have helped me immeasurably throughout my time at the University of Texas, and I wish that everyone could benefit from teachers so rigorous and open minded. I will never forget the compassion and strength that they demonstrated over the course of this project. Zoltan Barany developed my skills as a teacher, and provided a thoughtful reading of my first peer-reviewed article. David M. Buss kept an open mind when I approached him about this interdisciplinary project, and has remained a model of patience while I worked towards its completion. My work with Tom Palaima and Paul Woodruff began with collaboration, and then moved to friendship. Inevitably, I became their student, though they had been teaching me all along. -
The Importance of the War at Sea During WWI
The Importance of The War At Sea During WWI By: Taylor Pressdee, Anna Ward, Nathan Urquidi What Was the Impact of ‘The War at Sea’? ● Opened a new kind of warfare: Submarine Warfare ● Involved civilians as well as sailors and soldiers ● One of the major reasons that the United States joined the Allies ● Influenced major events during the war: Battle of Jutland, the naval blockade, submarine warfare and the sinking of the Lusitania Who Was Affected By The War at Sea? ● “Total War” ● War At Sea affected civilians as well as soldiers ● Ship Liners, and Coastal cities were in danger of attack ● Starvation was prevalent in specifically Germany because supply ships were being sunk Timeline May 31st 1916 September 1915 Battle of Jutland Germans stop using U-boats February 1st 1916 Germans begin using U-boats again May 7th 1916 Lusitania Sinks Battle of Jutland Battle of Jutland ● Fought on May 31st 1916 ● Only major battle fought at sea ● Fought by the Jutland Peninsula between England and Germany ● Two Admirals in charge of both fleets: Vice Admiral Reinhard Scheer (Left) and Admiral Sir John Jellicoe (Right) The Battle ● British forces intercepted a German message containing a plan to attack them on May 28th ● However, Admiral Scheer postponed the attack due to bad weather ○ Attempted to plan another attack down by the Jutland Peninsula, however Britain intercepted this plan as well ● Vice Admiral Jellicoe moved his fleet down to the Jutland Peninsula, awaiting the attack Aftermath of the Battle ● The British suffered losses, but not nearly -
© 2014 Alejandro Jose Gomez-Del-Moral ALL RIGHTS
© 2014 Alejandro Jose Gomez-del-Moral ALL RIGHTS RESERVED BUYING INTO CHANGE: CONSUMER CULTURE AND THE DEPARTMENT STORE IN THE TRANSFORMATION(S) OF SPAIN, 1939-1982 By ALEJANDRO JOSE GOMEZ-DEL-MORAL A dissertation submitted to the Graduate School-New Brunswick Rutgers, The State University of New Jersey In partial fulfillment of the requirements For the degree of Doctor of Philosophy Graduate Program in History Written under the direction of Temma Kaplan And approved by ________________________________ ________________________________ ________________________________ ________________________________ New Brunswick, New Jersey October 2014 ABSTRACT OF THE DISSERTATION Buying Into Change: Consumer Culture and the Department Store in the Transformation(s) of Spain, 1939-1982 by ALEJANDRO JOSE GOMEZ-DEL-MORAL Dissertation Director: Temma Kaplan This dissertation examines how the development of a mass consumer society during the dictatorship of Generalissimo Francisco Franco (1939-1975) inserted Spain into transnational consumer networks and drove its democratization. As they spread, Spain’s first modern department stores, supermarkets, consumer magazines, and advertising helped create a public sphere when the Franco regime had curtailed opportunities for public life. In these stores, Spanish consumers encountered foreign products and lifestyles that signaled cosmopolitanism and internationalism, undermining the dictatorship’s foundational discourse of Spanish exceptionalism. With these products came subversive ideas on issues like gender equality, -
NURS 4341.561 Cultural and Spirituality in Nursing
Summer 2021 Summer 2021 NURS 4341.561 Cultural and Spirituality in Nursing Belinda Deal, RN, PhD, CNE Office: BRB 2085 Office Hours: Online and by appointment Email: [email protected] - Preferred method of communication Phone: 903-566-7120 (work phone that will record a message in my email) 903-530-3787 Julie George, PhD, RN Office: PMH 118 Office Hours: Online and by appointment Email: [email protected] - Preferred method of communication Phone: 936-208-9418 Page 1 of 9 Updated 9/30/2020 BKH Summer 2021 Course Description This course will explore major world cultures and concepts of spirituality. Emphasis will be on the healthcare team and interaction with patients/clients. Why students should take this course: Increase understanding of a variety of cultures and belief systems in order to provide better holistic care. Course Learning Objectives Upon successful completion of this course, the student will be able to: 1. Patient Centered Care: Recognize individual’s preferences, values, and needs; anticipate the uniqueness of all individuals, families, and populations; and incorporate the patient/family/population in the plan and implementation of care. 2. Evidence Based Practice: Synthesize and apply evidence, along with clinical expertise and patient values, to improve patient outcomes related to cultural and spiritual values. 3. Teamwork and Collaboration: Function effectively in nursing and interprofessional teams and foster communication, mutual respect, and shared decision-making to achieve quality patient care. 4. Wellness and Prevention: Assess health and wellness in individuals, families, groups, communities, and populations to promote health outcomes. Grading Policy and Criteria Specific guidelines and grading criteria for all assignments are in the Modules.