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Legally Defensible Steroid Testing Services

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Legally Defensible Steroid Testing Services LGC in drug and alcohol testing Legally defensible steroid testing services Anabolic steroid misuse has Anabolic steroids, technically known as anabolic- historically been associated with sport androgenic steroids (AAS), are drugs that are structurally related to the naturally produced and doping scandals over the past steroid testosterone. They increase protein within 25 years. More recently, due in part cells, especially in skeletal muscles. Anabolic to their ready availability over the steroids also have androgenic and virilising internet both as steroid preparations properties, including the development and and as constituents of steroid based maintenance of masculine characteristics such as the growth of the vocal cords, testicles (primary nutritional supplements, the misuse of sexual characteristics) and body hair (secondary anabolic steroids has spread to wider sexual characteristics). areas of society including regular gym users and sub-elite sportspeople. www.lgcgroup.com/steroids • [email protected] Science for a safer world Brazil • Bulgaria • China • Czech Republic • France • Germany • Hungary • India • Ireland • Italy • Netherlands Poland • Romania • Russia • Scandanavia • South Africa • Spain • Turkey • United Kingdom • USA No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording or any retrieval system, without the written permission of the copyright holder. © LGC Limited, 2014. All rights reserved. 3995/LB/0814 Anabolic steroids were first synthesized in the and for cause workplace screen for anabolic Bolasterone 1930s, and are now used therapeutically in steroids. This premier service is comparable to that Boldenone medicine to stimulate bone growth and appetite, currently provided by WADA accredited laboratories Boldione Calusterone induce male puberty and treat chronic wasting supporting doping control programmes in sport. Clostebol (4-Chlorotestosterone) conditions, such as cancer and AIDS. The American Danazol College of Sports Medicine acknowledges that AAS, Dehydrochlormethyltestosterone (Chloromethandienone) in the presence of adequate diet, can contribute Urine tests are performed under UKAS ISO17025 DHEA to increases in body weight, often as lean mass accreditation on state of the art analytical Delta-1-testosterone increases and that the gains in muscular strength instrumentation offering performance and coverage Desoxymethyltestosterone (madol) unrivalled in the occupational drug testing sector. Drostanolone achieved through high-intensity exercise and proper Epitestosterone diet can be additionally increased by the use of Ethisterone AAS in some individuals. Ethylestrenol Fluoxymesterone Long term use or excessive does of anabolic Anabolic steroid coverage Gestrinone steroids are associated with significant health Mestanolone Analyte coverage is based on the list below but the risks. These effects include harmful changes in Mesterolone cholesterol levels (increased low-density lipoprotein screening approach taken gives us the ability to Metandienone and decreased high-density lipoprotein), acne, detect, identify and report new ‘designer’ anabolic Metenolone high blood pressure, liver damage (mainly with oral steroids. Methandriol Methasterone steroids), and dangerous changes in the structure of Methyl-1-testosterone the left ventricle of the heart. Conditions pertaining Methyldrostanolone to hormonal imbalances such as gynecomastia and Methyldienolone testicular atrophy may also be caused by anabolic Methylnortestosterone (17a methyl nortestosterone) steroids. Methyltestosterone Methyltrienolone Mibolerone Testing Nandrolone Drawing on our experience as a former World Anti Norandrostenediol (bolandiol) Norandrostenedione Doping Agency (WADA) accredited laboratory Norbolethone and over 30 years experience in steroid analysis Norethandrolone in sport, LGC offers a pre-employment, random Oxandrolone Oxymesterone Oxymetholone Stanozolol Stenbolone Testosterone Tetrahydrogestrinone Trenbolone X-tren Anabolic steroid misuse has historically been Confirmation to legally defensible standards associated with sport and All screening findings are confirmed by mass spectrometric techniques using certified reference doping scandals over the standards to WADA standards. The resulting data is legally defensible. past 25 years. For further information on steroid testing, please email: [email protected] or call +44(0)1638 720500..
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    Ann Toxicol Anal. 2012; 24(2): 67-72 Available online at: c Société Française de Toxicologie Analytique 2012 www.ata-journal.org DOI: 10.1051/ata/2012011 Original article / Article original A simple toxicological analysis of anabolic steroid preparations from the black market Analyse toxicologique simple de stéroïdiens anabolisants provenant de marchés parallèles Manuela Pellegrini, Maria Concetta Rotolo, Rita Di Giovannadrea, Roberta Pacifici, Simona Pichini Department of Therapeutic Research and Medicine Evaluation, Istituto Superiore di Sanità, Via le Regina Elena 299, 00161 Rome, Italy Abstract – Objectives: A simple and rapid gas chromatography (GC) method with mass spectrometry (MS) detection was developed for the identification and quantification of anabolic steroids in pharmaceutical preparations from the black market. Material and Methods: After a liquid-liquid extraction of pharmaceutical products at acidic, neutral and basic pH with chloroform-isopropanol (9:1, v/v), the different steroids were separated by fused silica capillary column and detected by electron impact (EI)-MS in positive ionization mode. Results and Conclusion: The assay was validated in the range from 10 mg to 250 mg/g powder preparations and 0.02 mg to 200 mg/mL liquid preparations with good determination coefficients (r2 0.99) for the calibration curves. At three concentrations spanning the linear dynamic ranges of the calibration curves, mean recoveries were always higher than 90% and intra-assay and inter-assay precision and accuracy were always better than 15%. This method was successfully applied to the analysis of 15 pharmaceutical preparations sold by illegal sources. In only two cases the content was the one reported on the labels.
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