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Rapport 2008 rapport 2008 Reseptregisteret 2004-2007 The Norwegian Prescription Database 2004-2007 Marit Rønning Christian Lie Berg Kari Furu Irene Litleskare Solveig Sakshaug Hanne Strøm Rapport 2008 Nasjonalt folkehelseinstitutt/ The Norwegian Institute of Public Health Tittel/Title: Reseptregisteret 2004-2007 The Norwegian Prescription Database 2004-2007 Redaktør/Editor: Marit Rønning Forfattere/Authors: Christian Lie Berg Kari Furu Irene Litleskare Marit Rønning Solveig Sakshaug Hanne Strøm Publisert av/Published by: Nasjonalt folkehelseinstitutt Postboks 4404 Nydalen NO-0403 Norway Tel: + 47 21 07 70 00 E-mail: [email protected] www.fhi.no Design: Per Kristian Svendsen Layout: Grete Søimer Acknowledgement: Julie D.W. Johansen (English version) Forsideillustrasjon/Front page illustration: Colourbox.com Trykk/Print: Nordberg Trykk AS Opplag/ Number printed: 1200 Bestilling/Order: [email protected] Fax: +47-21 07 81 05 Tel: +47-21 07 82 00 ISSN: 0332-6535 ISBN: 978-82-8082-252-9 trykt utgave/printed version ISBN: 978-82-8082-253-6 elektronisk utgave/electronic version 2 Rapport 2008 • Folkehelseinstituttet Forord Bruken av legemidler i befolkningen er økende. En viktig målsetting for norsk legemiddelpolitikk er rasjonell legemiddelbruk. En forutsetning for arbeidet med å optimalisere legemiddelbruken i befolkningen er kunnskap om hvilke legemidler som brukes, hvem som bruker legemidlene og hvordan de brukes. For å få bedre kunnskap på dette området, vedtok Stortinget i desember 2002 å etablere et nasjonalt reseptbasert legemiddelregister (Reseptregisteret). Oppgaven med å etablere registeret ble gitt til Folkehelseinstituttet som fra 1. januar 2004 har mottatt månedlige opplysninger fra alle apotek om utlevering av legemidler til pasienter, leger og institusjoner. Denne rapporten er første utgave i en planlagt årlig statistikk fra Reseptregisteret. Målet med rapporten er å presentere Reseptregisteret og utvalgte data. Rapporten har tre deler. Del 1 inneholder generell informasjon om Reseptregisteret, legemiddelforskrivning, statistikk og måle- metoder. I del 2 presenteres en del nøkkeltall og kommentarer til utvalgte tema og lege- middelgrupper. Del 3 inneholder tabeller med opplysninger om antall individer som har fått utlevert legemidler etter resept fra apotekene i Norge i perioden 2004-2007. Opplysningene er fordelt på enkeltlegemidler og legemiddelgrupper. ATC (Anatomisk Teraputisk Kjemisk) klassifikasjon er benyttet i tabellene. For 2007 er informasjon om alders – og kjønnsfordeling og kostnader inkludert i tabellene. ATC/DDD versjon gjeldende fra januar 2008 er benyttet i rapporten, se også www.whocc.no Reseptregisteret har også en nettside der man kan finne informasjon om antall individer som har fått utlevert legemidler etter resept (prevalens), oppdelt etter kjønn, 10 års aldersgrupper og geografi (fylke eller helseregion). Nettstedet er: www.norpd.no (engelsk versjon) eller www.reseptregisteret.no (norsk versjon). Data er tilgjengelige fra 2004 og nettsiden blir årlig oppdatert i mars for foregående år. Det er også mulig å søke om utlevering av data fra Reseptregisteret til forskning eller til andre formål som er i henhold til formålet for Reseptregisteret. Mer informasjon om dette finnes i innledningen til bokens del 3 og på nettsiden til Folkehelseinstituttet (www.fhi.no). Avdeling for legemiddelepidemiologi Folkehelseinstituttet August 2008 Rapport 2008 • Folkehelseinstituttet 3 4 Rapport 2008 • Folkehelseinstituttet Preface The use of drugs in the population is increasing. An important goal of the health policies regarding pharmaceuticals in Norway is rational drug use. In order to improve drug use, knowledge about which drugs are used, how they are used and who uses them is vital. In December 2002, the Parliament decided to establish a national prescription database in Norway (NorPD). The task of building up the register was given to the Norwegian Institute of Public Health (NIPH). Since 1st January 2004, the institute has received monthly data on prescriptions from all Norwegian pharmacies. This report is the first edition in a planned annual statistical report from NorPD. The purpose of the report is to present NorPD and selected data. The report has three parts. Part 1 contains general information about NorPD, prescribing of medicines and drug statistics. The second part includes some key figures and comments about selected topics and drug groups. Part 3 contains tables with information about the number of individuals who had prescriptions dispensed from pharmacies in Norway during the period 2004-2007. The information includes particular drug substances as well as drug groups. ATC (Anatomical Therapeutic Chemical) classification is used in the tables. For 2007, information about age, gender and costs are included in the tables. The ATC/DDD version of January 2008 has been used in the report, see also www.whocc.no NorPD also has a web page where one can find information about the number of individuals who had prescriptions dispensed (prevalence), split by gender, 10-year age groups and geography (county or health region). The website is: www.norpd.no (English version) or www.reseptregisteret.no (Norwegian version). Data is available from 2004 and the website is annu- ally updated in March for the previous year. It is also possible to apply for data from NorPD for rese- arch or for other purposes which are according to the objectives of NorPD. More information about this can be found in the introduction to the book’s section 3, and at the website of the Norwegian Institute of Public Health (www.fhi.no). Department of Pharmacoepidemiology Norwegian Institute of Public Health August 2008 Rapport 2008 • Folkehelseinstituttet 5 Innhold Forord ....................................................................................................................................................................... 3 1. Generell innledning ..........................................................................................................................................11 1.1 Etableringen av Reseptregisteret .................................................................................................... 11 1.2 Reseptregisteret (NorPD) ...................................................................................................................12 Datainnsamling og variabler i Reseptregisteret ..................................................................12 Datasikkerhet .............................................................................................................................13 Kvalitetssikring ...........................................................................................................................14 1.3 Fastlegeordningen, apoteksystemet og refusjonssystemet .......................................................15 1.4 Grossistbasert legemiddelstatistikk ................................................................................................16 1.5 Anatomisk Terapeutisk Kjemisk (ATC) klassifikasjon ....................................................................17 1.6 Definert Døgndose (DDD) ....................................................................................................................18 1.7 WHO Collaborating Centre for Drug Statistics Methodology .......................................................18 2. Kommentarer til utvalgte tema og legemiddelgrupper ...........................................................................20 2.1 Utvalgte nøkkeltall fra Reseptregisteret ........................................................................................20 2.2 Legemiddelbruk hos eldre (≥70år) ....................................................................................................23 2.3 Hjerte/kar legemidler (ATC gruppe C og B01) .................................................................................25 2.4 Midler til diabetesbehandling (ATC gruppe A10) ............................................................................28 2.5 Antibakterielle midler til systemisk bruk (ATC gruppe J01) ..........................................................32 2.6 Legemidler med virkning på nervesystemet (ATC-gruppe N) .....................................................34 Smertestillende midler (ATC gruppe N02) ..............................................................................34 Antiepileptika (ATC gruppe N03) ..............................................................................................35 Angstdempende midler (ATC gruppe N05B) ..........................................................................35 Sovemidler(ATC gruppe N05C) .................................................................................................35 Antidepressiva (ATC gruppe N06A) .........................................................................................36 Midler mot ADHD (ATC gruppe N06BA) ..................................................................................36 Midler mot demens (ATC gruppe N06D) ..................................................................................36 Midler mot opioidavhengighet (ATC gruppe N07BC) ............................................................37 3. Reseptregisteret 2004-2007 – Hovedtabeller ....................................................................................................38 3.1 Beskrivelse av tabellene .....................................................................................................................38
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