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Biotecnología Y Desarrollo Documento de proyecto Biotecnología y desarrollo Roberto Bisang Mercedes Campi Verónica Cesa Comisión Económica para América Latina y el Caribe (CEPAL) Este documento fue preparado por Roberto Bisang y Verónica Cesa, consultores, y Mercedes Campi, asistente de investigación de la Oficina de la Comisión Económica para América Latina y el Caribe (CEPAL) en Buenos Aires a pedido de la Oficina de la Secretaría Ejecutiva de la CEPAL. Las opiniones expresadas en este documento, que no ha sido sometido a revisión editorial, son de exclusiva responsabilidad de los autores y pueden no coincidir con las de la Organización. Publicación de las Naciones Unidas LC/W.234 LC/BUE/W.35 Copyright © Naciones Unidas, marzo del 2009. Todos los derechos reservados Impreso en Naciones Unidas, Santiago de Chile La autorización para reproducir total o parcialmente esta obra debe solicitarse al Secretario de la Junta de Publicaciones, Sede de las Naciones Unidas, Nueva York, N. Y. 10017, Estados Unidos. Los Estados miembros y sus instituciones gubernamentales pueden reproducir esta obra sin autorización previa. Sólo se les solicita que mencionen la fuente e informen a las Naciones Unidas de tal reproducción. CEPAL – Colección Documentos de proyectos Biotecnología y desarrollo Índice Resumen .................................................................................................................................. 5 I. Introducción ............................................................................................................................. 7 II. De la biotecnología a la producción....................................................................................... 11 1. Biotecnología: Aplicaciones e impactos (un mundo desafiante) ................................... 11 1.1 Introducción: De la biología tradicional a la moderna biotecnología...................... 11 1.2 De la biotecnología como ciencia a la tecnología aplicada: ¿Una nueva plataforma de negocios? ................................................................... 14 2. Aplicaciones de la moderna biotecnología en la producción......................................... 16 2.1 Aplicaciones a la ganadería ................................................................................... 16 2.2 Aplicaciones a la genética vegetal ......................................................................... 19 2.3 Aplicaciones industriales ........................................................................................ 22 III El desarrollo productivo de la biotecnología a nivel mundial................................................. 31 1. Panorama general.......................................................................................................... 31 2. Las principales aplicaciones: Genética vegetal, industria farmacéutica y alimentos .... 33 2.1 Genética Vegetal: Las mega corporaciones de las “ciencias de la vida”............... 33 2.2 Industria farmacéutica ............................................................................................ 38 2.3 Ingredientes para la industria alimenticia............................................................... 39 3. Desempeño reciente y modelo de funcionamiento........................................................ 40 3.1 Genética Vegetal: Las mega corporaciones de las “ciencias de la vida”............... 49 4. Los principales “sectores usuarios” de biotecnología: Organización, rentas y desarrollo .................................................................................. 55 4.1 Agro y alimentos..................................................................................................... 55 4.2 Medicamentos y salud humana.............................................................................. 58 IV. La producción de biotecnología en países de la región. ¿Esfuerzos públicos, desarrollos privados, ilusiones colectivas?............................................................................ 61 1. Encuadre: ¿Por qué surgen desarrollos biotecnológicos endógenos en los países de la región? ............................................................................................ 61 2. El susbsistema público................................................................................................... 63 2.1 De las instituciones de CyT a la biotecnología ...................................................... 63 2.2 Investigación y desarrollo en biotecnología: Recursos, organización y estrategia en el sector público ....................................................... 64 3. El subsistema privado de “producción” de moderna biotecnología............................... 69 3.1 Panorama general.................................................................................................. 69 3 CEPAL – Colección Documentos de proyectos Biotecnología y desarrollo 3.2 Argentina ................................................................................................................ 69 3.3 Brasil....................................................................................................................... 73 3.4 Chile........................................................................................................................ 74 3.5 Colombia ................................................................................................................ 75 3.6 Cuba....................................................................................................................... 75 3.7 Uruguay .................................................................................................................. 77 4. Empresas, tamaños y estrategias.................................................................................. 78 5. Aguas abajo: Uso de la biotecnología, formas de organización de la producción y del comercio internacional....................................................................... 80 V. Reflexiones finales................................................................................................................. 83 Bibliografía..................................................................................................................................... 89 Anexos ....................................................................................................................................... 93 4 CEPAL – Colección Documentos de proyectos Biotecnología y desarrollo Resumen La irrupción de la biotecnología aplicada a diversas actividades productivas impacta, crecientemente, sobre los senderos previos de desarrollo de los países latinoamericanos. Por sus rasgos intrínsecos, la biotecnología -“industria de bienes de capital de la sociedad del conocimiento”- abre nuevos espacios de intercambio público-privado a nivel científico, tecnológico y productivo; bajo ciertas condiciones (umbrales mínimos de conocimiento, facilidades técnicas y productivas, derechos de propiedad, desarrollo de las actividades “aguas abajo”, control de los activos complementarios) estos nuevos espacios de intercambio generan o potencian mercados a partir de los cuales es factible captar rentas adicionales. El presente trabajo analiza los efectos y posibilidades de la biotecnología moderna sobre el sendero de desarrollo de los principales países de la región. Para ello se delinean los rasgos centrales de esta tecnología y sus impactos sobre los procesos productivos, así como, también, la dinámica reciente que tienen las aplicaciones de estas tecnologías en la producción en los países desarrollados, poniendo énfasis en las mega-corporaciones de la biotecnología. Asimismo, se realiza un análisis de los principales desarrollos biotecnológicos en los países latinoamericanos, que incluye una revisión de los esfuerzos públicos y de los incipientes desarrollos privados (con su aplicación a algunas actividades productivas relevantes). Por último, el trabajo se completa con una serie de reflexiones acerca de las posibilidades (y limitaciones) que plantean estas tecnologías para los países de la región. 5 CEPAL – Colección Documentos de proyectos Biotecnología y desarrollo I. Introducción En las últimas décadas ha cobrado mayor fuerza en las agendas de las discusiones de políticas públicas de la región el tema referido al desarrollo. Luego de un fuerte predominio de las cuestiones relacionadas con los (des)equilibrios macroeconómicos, los problemas fiscales y/o los temas institucionales, recobra vigor el tratamiento del crecimiento y su relación con el desarrollo. Dos elementos centrales contribuyen a este proceso. Por un lado, los impactos que devienen de los cambios relacionados con las nuevas tecnologías -TICS y biológicas- que, dado su carácter schumpeteriano, van camino a modificar estructuras productivas e instituciones (públicas y privadas) (Magariños 2006; Katz y Bárcena, 2004; PROCISUR, 2001; Riftkin, 1998; Sasson, 1993; Orsenigo, 1990). Por otro, y con particular relevancia en el último lustro, en la casi totalidad de los países de la region, se ha producido una creciente generación de rentas adicionales asociadas con los superávit de comercio internacional. Sin mayores cambios en la composición estructural, parte relevante de esta dinámica se basa en mejoras en los términos de intercambio1. De esta forma, se verifica la presencia de una condición necesaria para reenfocar los procesos de crecimiento y posterior desarrollo: existen rentas adicionales que “desequilibran” 1 En mayor o menor medida (según países y perfiles de inserción externa), las
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