DOCSLIB.ORG

Controlled Drugs and Substances Act Loi Réglementant

Total Page：16

File Type：pdf, Size：1020Kb

Download full-text PDF Read full-text
Controlled Drugs and Substances Act Loi Réglementant CANADA CONSOLIDATION CODIFICATION Controlled Drugs and Loi réglementant Substances Act certaines drogues et autres substances S.C. 1996, c. 19 L.C. 1996, ch. 19 Current to February 9, 2011 À jour au 9 février 2011 Published by the Minister of Justice at the following address: Publié par le ministre de la Justice à l’adresse suivante : http://laws-lois.justice.gc.ca http://lois-laws.justice.gc.ca OFFICIAL STATUS CARACTÈRE OFFICIEL OF CONSOLIDATIONS DES CODIFICATIONS Subsections 31(1) and (2) of the Legislation Les paragraphes 31(1) et (2) de la Loi sur la Revision and Consolidation Act, in force on révision et la codification des textes législatifs, June 1, 2009, provide as follows: en vigueur le 1er juin 2009, prévoient ce qui suit : Published 31. (1) Every copy of a consolidated statute or 31. (1) Tout exemplaire d'une loi codifiée ou Codifications consolidation is consolidated regulation published by the Minister d'un règlement codifié, publié par le ministre en ver- comme élément evidence under this Act in either print or electronic form is ev- tu de la présente loi sur support papier ou sur support de preuve idence of that statute or regulation and of its contents électronique, fait foi de cette loi ou de ce règlement and every copy purporting to be published by the et de son contenu. Tout exemplaire donné comme Minister is deemed to be so published, unless the publié par le ministre est réputé avoir été ainsi pu- contrary is shown. blié, sauf preuve contraire. Inconsistencies (2) In the event of an inconsistency between a (2) Les dispositions de la loi d'origine avec ses Incompatibilité in Acts consolidated statute published by the Minister under modifications subséquentes par le greffier des Parle- — lois this Act and the original statute or a subsequent ments en vertu de la Loi sur la publication des lois amendment as certified by the Clerk of the Parlia- l'emportent sur les dispositions incompatibles de la ments under the Publication of Statutes Act, the orig- loi codifiée publiée par le ministre en vertu de la pré- inal statute or amendment prevails to the extent of sente loi. the inconsistency. 1996, c. 19 1996, ch. 19 An Act respecting the control of certain drugs, Loi portant réglementation de certaines drogues their precursors and other substances and et de leurs précurseurs ainsi que d’autres to amend certain other Acts and repeal the substances, modifiant certaines lois et Narcotic Control Act in consequence abrogeant la Loi sur les stupéfiants en thereof conséquence [Assented to 20th June 1996] [Sanctionnée le 20 juin 1996] Her Majesty, by and with the advice and Sa Majesté, sur l’avis et avec le consente- consent of the Senate and House of Commons ment du Sénat et de la Chambre des communes of Canada, enacts as follows: du Canada, édicte : SHORT TITLE TITRE ABRÉGÉ Short title 1. This Act may be cited as the Controlled 1. Loi réglementant certaines drogues et Titre abrégé Drugs and Substances Act. autres substances. INTERPRETATION DÉFINITIONS ET INTERPRÉTATION Definitions 2. (1) In this Act, 2. (1) Les définitions qui suivent s’ap- Définitions pliquent à la présente loi. “adjudicator” “adjudicator” means a person appointed or em- « arbitre » ployed under the Public Service Employment « analogue » Qualifie toute substance dont la « analogue » Act who performs the duties and functions of structure chimique est essentiellement la même “analogue” an adjudicator under this Act and the regula- que celle d’une substance désignée. tions; « analyste » Personne désignée à ce titre en ap- « analyste » “analyst” “analogue” “analogue” means a substance that, in relation plication de l’article 44. « analogue » to a controlled substance, has a substantially « arbitre » Personne nommée ou employée sous « arbitre » similar chemical structure; le régime de la Loi sur l’emploi dans la fonc- “adjudicator” “analyst” “analyst” means a person who is designated as tion publique et exerçant à ce titre les attribu- « analyste » an analyst under section 44; tions prévues par la présente loi et ses règle- ments. “Attorney “Attorney General” means General” «bien infractionnel » Bien situé au Canada ou à « bien « procureur (a) the Attorney General of Canada, and in- infractionnel » général » l’extérieur du Canada, à l’exception des sub- cludes their lawful deputy, or “offence-related stances désignées, qui sert ou donne lieu à la property” (b) with respect to proceedings commenced perpétration d’une infraction désignée ou qui at the instance of the government of a est utilisé de quelque manière dans la perpétra- province and conducted by or on behalf of tion d’une telle infraction, ou encore qui est that government, the Attorney General of destiné à servir à une telle fin. that province, and includes their lawful deputy; 1 Controlled Drugs and Substances — February 9, 2011 “controlled “controlled substance” means a substance in- « fournir » Procurer, même indirectement et no- « fournir » substance” cluded in Schedule I, II, III, IV or V; tamment par don ou transfert, en échange ou “provide” « substance désignée » non d’une contrepartie. “designated “designated substance offence” means « infraction désignée » Soit toute infraction pré- « infraction substance vue par la partie I, à l’exception du paragraphe désignée » offence” (a) an offence under Part I, except subsec- “designated « infraction tion 4(1), or 4(1), soit le complot ou la tentative de com- substance désignée » mettre une telle infraction, la complicité après offence” (b) a conspiracy or an attempt to commit, le fait à son égard ou le fait de conseiller de la being an accessory after the fact in relation commettre. to, or any counselling in relation to, an of- fence referred to in paragraph (a); « inspecteur » Personne désignée à ce titre en « inspecteur » application de l’article 30. “inspector” “inspector” “inspector” means a person who is designated « inspecteur » as an inspector under section 30; « juge » Juge au sens de l’article 552 du Code « juge » criminel ou tout juge d’une cour supérieure de “judge” “judge” “judge” means a judge as defined in section compétence criminelle. « juge » 552 of the Criminal Code or a judge of a supe- rior court of criminal jurisdiction; « juge de paix » S’entend au sens de l’article 2 « juge de paix » du Code criminel. “justice” “justice” “justice” has the same meaning as in section 2 « juge de paix » of the Criminal Code; « ministre » Le ministre de la Santé. « ministre » “Minister” “Minister” “Minister” means the Minister of Health; «possession» S’entend au sens du paragraphe « possession » « ministre » 4(3) du Code criminel. “possession” “offence-related “offence-related property” means, with the ex- property” ception of a controlled substance, any property, « praticien » Personne qui, en vertu des lois « praticien » « bien d’une province, est agréée et est autorisée à “practitioner” infractionnel » within or outside Canada, exercer dans cette province la profession de (a) by means of or in respect of which a des- médecin, de dentiste ou de vétérinaire. Y sont ignated substance offence is committed, assimilées toute autre personne ou catégorie de (b) that is used in any manner in connection personnes désignées par règlement. with the commission of a designated sub- « précurseur » Substance inscrite à l’annexe VI. « précurseur » stance offence, or “precursor” (c) that is intended for use for the purpose of « procureur général » « procureur committing a designated substance offence; général » a) Le procureur général du Canada et son “Attorney General” “possession” “possession” means possession within the substitut légitime; « possession » meaning of subsection 4(3) of the Criminal b) à l’égard des poursuites intentées à la de- Code; mande du gouvernement d’une province et “practitioner” “practitioner” means a person who is registered menées par ce dernier ou en son nom, le pro- « praticien » and entitled under the laws of a province to cureur général de cette province et son sub- practise in that province the profession of stitut légitime. medicine, dentistry or veterinary medicine, and « production » Relativement à une substance « production » includes any other person or class of persons inscrite à l’une ou l’autre des annexes I à IV, le “produce” prescribed as a practitioner; fait de l’obtenir par quelque méthode que ce “precursor” “precursor” means a substance included in soit, et notamment par : « précurseur » Schedule VI; a) la fabrication, la synthèse ou tout autre “prescribed” “prescribed” means prescribed by the regula- moyen altérant ses propriétés physiques ou Version anglaise tions; chimiques; seulement b) la culture, la multiplication ou la récolte “produce” “produce” means, in respect of a substance in- « production » cluded in any of Schedules I to IV, to obtain the de la substance ou d’un organisme vivant substance by any method or process including dont il peut être extrait ou provenir de toute autre façon. 2 Drogues et autres substances — 9 février 2011 (a) manufacturing, synthesizing or using any Y est assimilée l’offre de produire. means of altering the chemical or physical « substance désignée » Substance inscrite à « substance properties of the substance, or l’une ou l’autre des annexes I, II, III, IV ou V. désignée » “controlled (b) cultivating, propagating or harvesting the substance” substance or any living thing from which the « trafic » Relativement à une substance inscrite « trafic » substance may be extracted or otherwise ob- à l’une ou l’autre des annexes I à IV, toute opé- “traffic” tained, ration de vente — y compris la vente d’une au- and includes offer to produce; torisation visant son obtention — , d’adminis- tration, de don, de cession, de transport, “provide” “provide” means to give, transfer or otherwise d’expédition ou de livraison portant sur une « fournir » make available in any manner, whether directly telle substance — ou toute offre d’effectuer or indirectly and whether or not for considera- l’une de ces opérations — qui sort du cadre ré- tion; glementaire.
Load more

Recommended publications
  • Medicines Regulations 1984 (SR 1984/143)
    Reprint as at 1 July 2014 Medicines Regulations 1984 (SR 1984/143) David Beattie, Governor-General Order in Council At the Government House at Wellington this 5th day of June 1984 Present: His Excellency the Governor-General in Council Pursuant to section 105 of the Medicines Act 1981, and, in the case of Part 3 of the regulations, to section 62 of that Act, His Excellency the Governor-General, acting on the advice of the Minister of Health tendered after consultation with the organisations and bodies that ap- peared to the Minister to be representatives of persons likely to be substantially affected, and by and with the advice and consent of the Executive Council, hereby makes the following regulations. Contents Page 1 Title and commencement 5 Note Changes authorised by subpart 2 of Part 2 of the Legislation Act 2012 have been made in this official reprint. Note 4 at the end of this reprint provides a list of the amendments incorporated. These regulations are administered by the Ministry of Health. 1 Reprinted as at Medicines Regulations 1984 1 July 2014 2 Interpretation 5 Part 1 Classification of medicines 3 Classification of medicines 11 Part 2 Standards 4 Standards for medicines, related products, medical 11 devices, cosmetics, and surgical dressings 5 Pharmacist may dilute medicine in particular case 12 6 Colouring substances [Revoked] 12 Part 3 Advertisements 7 Advertisements not to claim official approval 13 8 Advertisements for medicines 13 9 Advertisements for related products 15 10 Advertisements for medical devices 15 11 Advertisements
    [Show full text]
  • Part I Biopharmaceuticals
    1 Part I Biopharmaceuticals Translational Medicine: Molecular Pharmacology and Drug Discovery First Edition. Edited by Robert A. Meyers. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA. Published 2018 by Wiley-VCH Verlag GmbH & Co. KGaA. 3 1 Analogs and Antagonists of Male Sex Hormones Robert W. Brueggemeier The Ohio State University, Division of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Columbus, Ohio 43210, USA 1Introduction6 2 Historical 6 3 Endogenous Male Sex Hormones 7 3.1 Occurrence and Physiological Roles 7 3.2 Biosynthesis 8 3.3 Absorption and Distribution 12 3.4 Metabolism 13 3.4.1 Reductive Metabolism 14 3.4.2 Oxidative Metabolism 17 3.5 Mechanism of Action 19 4 Synthetic Androgens 24 4.1 Current Drugs on the Market 24 4.2 Therapeutic Uses and Bioassays 25 4.3 Structure–Activity Relationships for Steroidal Androgens 26 4.3.1 Early Modifications 26 4.3.2 Methylated Derivatives 26 4.3.3 Ester Derivatives 27 4.3.4 Halo Derivatives 27 4.3.5 Other Androgen Derivatives 28 4.3.6 Summary of Structure–Activity Relationships of Steroidal Androgens 28 4.4 Nonsteroidal Androgens, Selective Androgen Receptor Modulators (SARMs) 30 4.5 Absorption, Distribution, and Metabolism 31 4.6 Toxicities 32 Translational Medicine: Molecular Pharmacology and Drug Discovery First Edition. Edited by Robert A. Meyers. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA. Published 2018 by Wiley-VCH Verlag GmbH & Co. KGaA. 4 Analogs and Antagonists of Male Sex Hormones 5 Anabolic Agents 32 5.1 Current Drugs on the Market 32 5.2 Therapeutic Uses and Bioassays
    [Show full text]
  • A10 Anabolic Steroids Hardcore Info
    CONTENTS GENERAL INFORMATION 3 Anabolic steroids – What are they? 4 How do they Work? – Aromatisation 5 More molecules – More problems 6 The side effects of anabolic steroids 7 Women and anabolic steroids 8 Injecting steroids 9 Abscesses – Needle Exchanges 10 Intramuscular injection 11 Injection sites 12 Oral steroids – Cycles – Stacking 13 Diet 14 Where do steroids come from? Spotting a counterfeit 15 Drug Information – Drug dosage STEROIDS 16 Anadrol – Andriol 17 Anavar – Deca-Durabolin 18 Dynabolon – Durabolin – Dianabol 19 Esiclene – Equipoise 20 Primobolan Depot – Proviron – Primobolan orals – Pronobol 21 Sustanon – Stromba, Strombaject – Testosterone Cypionate Testosterone Enanthate 22 Testosterone Propionate – Testosterone Suspension 23 Trenbolone Acetate – Winstrol OTHER DRUGS 24 Aldactone – Arimidex 25 Clenbuterol – Cytomel 26 Ephedrine Hydrochloride – GHB 27 Growth Hormone 28 Insulin 30 Insulin-Like Growth Factor-1 – Human Chorionic Gonadotrophin 31 Tamoxifen – Nubain – Recreational Drugs 32 Steroids and the Law 34 Glossary ANABOLIC STEROIDS People use anabolic steroids for various reasons, some use them to build muscle for their job, others just want to look good and some use them to help them in sport or body building. Whatever the reason, care needs to be taken so that as little harm is done to the body as possible because despite having muscle building effects they also have serious side effects especially when used incorrectly. WHAT ARE THEY? Anabolic steroids are man made versions of the hormone testosterone. Testosterone is the chemical in men responsible for facial hair, deepening of the voice and sex organ development, basically the masculine things Steroids are in a man. used in medicine to treat anaemia, muscle weakness after These masculine effects surgery etc, vascular are called the androgenic disorders and effects of testosterone.
    [Show full text]
  • (12) United States Patent (10) Patent No.: US 6,264,917 B1 Klaveness Et Al
    USOO6264,917B1 (12) United States Patent (10) Patent No.: US 6,264,917 B1 Klaveness et al. (45) Date of Patent: Jul. 24, 2001 (54) TARGETED ULTRASOUND CONTRAST 5,733,572 3/1998 Unger et al.. AGENTS 5,780,010 7/1998 Lanza et al. 5,846,517 12/1998 Unger .................................. 424/9.52 (75) Inventors: Jo Klaveness; Pál Rongved; Dagfinn 5,849,727 12/1998 Porter et al. ......................... 514/156 Lovhaug, all of Oslo (NO) 5,910,300 6/1999 Tournier et al. .................... 424/9.34 FOREIGN PATENT DOCUMENTS (73) Assignee: Nycomed Imaging AS, Oslo (NO) 2 145 SOS 4/1994 (CA). (*) Notice: Subject to any disclaimer, the term of this 19 626 530 1/1998 (DE). patent is extended or adjusted under 35 O 727 225 8/1996 (EP). U.S.C. 154(b) by 0 days. WO91/15244 10/1991 (WO). WO 93/20802 10/1993 (WO). WO 94/07539 4/1994 (WO). (21) Appl. No.: 08/958,993 WO 94/28873 12/1994 (WO). WO 94/28874 12/1994 (WO). (22) Filed: Oct. 28, 1997 WO95/03356 2/1995 (WO). WO95/03357 2/1995 (WO). Related U.S. Application Data WO95/07072 3/1995 (WO). (60) Provisional application No. 60/049.264, filed on Jun. 7, WO95/15118 6/1995 (WO). 1997, provisional application No. 60/049,265, filed on Jun. WO 96/39149 12/1996 (WO). 7, 1997, and provisional application No. 60/049.268, filed WO 96/40277 12/1996 (WO). on Jun. 7, 1997. WO 96/40285 12/1996 (WO). (30) Foreign Application Priority Data WO 96/41647 12/1996 (WO).
    [Show full text]
  • WO 2012/148799 Al 1 November 2012 (01.11.2012) P O P C T
    (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (10) International Publication Number (43) International Publication Date WO 2012/148799 Al 1 November 2012 (01.11.2012) P O P C T (51) International Patent Classification: (81) Designated States (unless otherwise indicated, for every A61K 9/107 (2006.01) A61K 9/00 (2006.01) kind of national protection available): AE, AG, AL, AM, A 61 47/10 (2006.0V) AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, (21) International Application Number: DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, PCT/US2012/034361 HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, (22) International Filing Date: KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, 20 April 2012 (20.04.2012) MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, (25) Filing Language: English SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, (26) Publication Language: English TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (30) Priority Data: (84) Designated States (unless otherwise indicated, for every 61/480,259 28 April 201 1 (28.04.201 1) US kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, (71) Applicant (for all designated States except US): BOARD UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, MD, RU, OF REGENTS, THE UNIVERSITY OF TEXAS SYS¬ TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, TEM [US/US]; 201 West 7th St., Austin, TX 78701 (US).
    [Show full text]
  • Partial Agreement in the Social and Public Health Field
    COUNCIL OF EUROPE COMMITTEE OF MINISTERS (PARTIAL AGREEMENT IN THE SOCIAL AND PUBLIC HEALTH FIELD) RESOLUTION AP (88) 2 ON THE CLASSIFICATION OF MEDICINES WHICH ARE OBTAINABLE ONLY ON MEDICAL PRESCRIPTION (Adopted by the Committee of Ministers on 22 September 1988 at the 419th meeting of the Ministers' Deputies, and superseding Resolution AP (82) 2) AND APPENDIX I Alphabetical list of medicines adopted by the Public Health Committee (Partial Agreement) updated to 1 July 1988 APPENDIX II Pharmaco-therapeutic classification of medicines appearing in the alphabetical list in Appendix I updated to 1 July 1988 RESOLUTION AP (88) 2 ON THE CLASSIFICATION OF MEDICINES WHICH ARE OBTAINABLE ONLY ON MEDICAL PRESCRIPTION (superseding Resolution AP (82) 2) (Adopted by the Committee of Ministers on 22 September 1988 at the 419th meeting of the Ministers' Deputies) The Representatives on the Committee of Ministers of Belgium, France, the Federal Republic of Germany, Italy, Luxembourg, the Netherlands and the United Kingdom of Great Britain and Northern Ireland, these states being parties to the Partial Agreement in the social and public health field, and the Representatives of Austria, Denmark, Ireland, Spain and Switzerland, states which have participated in the public health activities carried out within the above-mentioned Partial Agreement since 1 October 1974, 2 April 1968, 23 September 1969, 21 April 1988 and 5 May 1964, respectively, Considering that the aim of the Council of Europe is to achieve greater unity between its members and that this
    [Show full text]
  • Order in Council 1243/1995
    PROVINCE OF BRITISH COLUMBIA ORDER OF THE LIEUTENANT GOVERNOR IN COUNCIL Order in Council No. 12 4 3 , Approved and Ordered OCT 121995 Lieutenant Governor Executive Council Chambers, Victoria On the recommendation of the undersigned, the Lieutenant Governor, by and with the advice and consent of the Executive Council, orders that Order in Council 1039 made August 17, 1995, is rescinded. 2. The Drug Schedules made by regulation of the Council of the College of Pharmacists of British Columbia, as set out in the attached resolution dated September 6, 1995, are hereby approved. (----, c" g/J1"----c- 4- Minister of Heal fandand Minister Responsible for Seniors Presidin Member of the Executive Council (This pan is for adnwustratlye purposes only and is not part of the Order) Authority under which Order Is made: Act and section:- Pharmacists, Pharmacy Operations and Drug Scheduling Act, section 59(2)(1), 62 Other (specify): - Uppodukoic1enact N6145; Resolution of the Council of the College of Pharmacists of British Columbia ("the Council"), made by teleconference at Vancouver, British Columbia, the 6th day of September 1995. RESOLVED THAT: In accordance with the authority established in Section 62 of the Pharmacists, Pharmacy Operations and Drug Scheduling Act of British Columbia, S.B.C. Chapter 62, the Council makes the Drug Schedules by regulation as set out in the attached schedule, subject to the approval of the Lieutenant Governor in Council. Certified a true copy Linda J. Lytle, Phr.) Registrar DRUG SCHEDULES to the Pharmacists, Pharmacy Operations and Drug Scheduling Act of British Columbia The Drug Schedules have been printed in an alphabetical format to simplify the process of locating each individual drug entry and determining its status in British Columbia.
    [Show full text]
  • Pharmaceutical Appendix to the Tariff Schedule 2
    Harmonized Tariff Schedule of the United States (2007) (Rev. 2) Annotated for Statistical Reporting Purposes PHARMACEUTICAL APPENDIX TO THE HARMONIZED TARIFF SCHEDULE Harmonized Tariff Schedule of the United States (2007) (Rev. 2) Annotated for Statistical Reporting Purposes PHARMACEUTICAL APPENDIX TO THE TARIFF SCHEDULE 2 Table 1. This table enumerates products described by International Non-proprietary Names (INN) which shall be entered free of duty under general note 13 to the tariff schedule. The Chemical Abstracts Service (CAS) registry numbers also set forth in this table are included to assist in the identification of the products concerned. For purposes of the tariff schedule, any references to a product enumerated in this table includes such product by whatever name known. ABACAVIR 136470-78-5 ACIDUM LIDADRONICUM 63132-38-7 ABAFUNGIN 129639-79-8 ACIDUM SALCAPROZICUM 183990-46-7 ABAMECTIN 65195-55-3 ACIDUM SALCLOBUZICUM 387825-03-8 ABANOQUIL 90402-40-7 ACIFRAN 72420-38-3 ABAPERIDONUM 183849-43-6 ACIPIMOX 51037-30-0 ABARELIX 183552-38-7 ACITAZANOLAST 114607-46-4 ABATACEPTUM 332348-12-6 ACITEMATE 101197-99-3 ABCIXIMAB 143653-53-6 ACITRETIN 55079-83-9 ABECARNIL 111841-85-1 ACIVICIN 42228-92-2 ABETIMUSUM 167362-48-3 ACLANTATE 39633-62-0 ABIRATERONE 154229-19-3 ACLARUBICIN 57576-44-0 ABITESARTAN 137882-98-5 ACLATONIUM NAPADISILATE 55077-30-0 ABLUKAST 96566-25-5 ACODAZOLE 79152-85-5 ABRINEURINUM 178535-93-8 ACOLBIFENUM 182167-02-8 ABUNIDAZOLE 91017-58-2 ACONIAZIDE 13410-86-1 ACADESINE 2627-69-2 ACOTIAMIDUM 185106-16-5 ACAMPROSATE 77337-76-9
    [Show full text]
  • Sedatives and Hypnotics.Docx
    Sedatives and Hypnotics .Hypnotics and sedative drugs are used to produce drowsiness and promote sleep. .These drugs depress the CNS. .A sedative drug decreases activity, excitements whereas a hypnotic drug produces drowsiness and facilitates the onset and maintenance of sleep as a natural sleep. Classification .According to chemical structures, sedative and hypnotics may be classified into following category:- A)-Barbiturates:- It is a cyclic ureids. Generic name R1 R2 R3 Barbital -Et - Et -H Long duration of action Mephobarbital (Methyl -Et -C6H5 -Me Long duration of action phenobarbitone) Phenobarbital -Et - C6H5 -H Long duration of action Allobarbital allyl allyl -H Intermediate duration of action Amobarbital -Et -C5H11 -H Intermediate duration of action Probarbital -Et -CH(CH3)2 -H Intermediate duration of action Pentobarbital -Et -CH(CH3)-(CH2) 2CH3 -H Short duration of action Methohexital -allyl -CH(CH3)-C≡C-CH2CH3 -1-Me Short duration of action Hexobarbital -Me -1-Me Short duration of action Thiopental (2-C=S) -Et -CH(CH3)-(CH2) 2CH3 -H Ultra Short acting barbiturates B)- Benzodiazepines:- R1 O 9 N 1 8 2 3 4 5 R 7 N 2 6 R3 Drug R1 R2 R3 Flurazepam -CH2CH2N(C2H5)2 -Cl -F Temazepam,(3-OH) -Me -Cl -H Quazepam,(2-C==S) -CH2CF3 -Cl -F C)- Non-Barbiturates and Non- Benzodiazepines:- Ex.- • Glutethimide C2H5 C6H5 O N O H • Chloral hydrate Cl OH Cl C OH H Cl • Paraldehyde CH3 O H O H H H C O CH 3 3 SAR of Barbiturates O 4 R1 5 H N R2 3 O 6 2 O N1 R3 • In general , structural changes that in case the lipid solubility, decrease duration of action, accelerate metabolic degradation and increase hypnotic potency.
    [Show full text]
  • Bond Elut Certify Methods Manual
    AGILENT BOND ELUT CERTIFY AND CERTIFY II METHODS MANUAL TABLE OF CONTENTS INTRODUCTION AND OVERVIEW OF THE MANUAL .................................3 M2724 Meperidine (Pethidine) in Urine by GC or GC/MS ........................... 49 SUMMARY OF BOND ELUT CERTIFY AND CERTIFY II M2725 Methadone in Urine by GC or GC/MS ............................................. 50 MIXED MODE EXTRACTION ............................................................................5 M2726 Methaqualone in Urine by GC or GC/MS ........................................ 51 METHOD OPTIMIZATION .................................................................................6 M2727A 6-Monoacetyl Morphine in Urine by GC or GC/MS ........................ 52 PART NUMBERS................................................................................................8 M2727B 6-Monoacetyl Morphine in Urine by LC or LC/MS ......................... 53 SOLVENTS, SOLVENT MIXTURES, REAGENTS, AND SOLUTIONS .............................................................................................11 M2728 Nicotine in Urine by GC or GC/MS ................................................... 54 EQUIPMENT AND ACCESSORIES ................................................................17 M2729 Opiates (Free/Unbound) in Serum, Plasma, or Whole Blood by GC or GC/MS....................................... 55 BOND ELUT CERTIFY EXTRACTION METHODS ........................................ 29 M2730A Opiates in Urine by GC or GC/MS .................................................... 56 M2707A
    [Show full text]
  • (12) Patent Application Publication (10) Pub. No.: US 2002/0102215 A1 100 Ol
    US 2002O102215A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2002/0102215 A1 Klaveness et al. (43) Pub. Date: Aug. 1, 2002 (54) DIAGNOSTIC/THERAPEUTICAGENTS (60) Provisional application No. 60/049.264, filed on Jun. 6, 1997. Provisional application No. 60/049,265, filed (75) Inventors: Jo Klaveness, Oslo (NO); Pal on Jun. 6, 1997. Provisional application No. 60/049, Rongved, Oslo (NO); Anders Hogset, 268, filed on Jun. 7, 1997. Oslo (NO); Helge Tolleshaug, Oslo (NO); Anne Naevestad, Oslo (NO); (30) Foreign Application Priority Data Halldis Hellebust, Oslo (NO); Lars Hoff, Oslo (NO); Alan Cuthbertson, Oct. 28, 1996 (GB)......................................... 9622.366.4 Oslo (NO); Dagfinn Lovhaug, Oslo Oct. 28, 1996 (GB). ... 96223672 (NO); Magne Solbakken, Oslo (NO) Oct. 28, 1996 (GB). 9622368.0 Jan. 15, 1997 (GB). ... 97OO699.3 Correspondence Address: Apr. 24, 1997 (GB). ... 9708265.5 BACON & THOMAS, PLLC Jun. 6, 1997 (GB). ... 9711842.6 4th Floor Jun. 6, 1997 (GB)......................................... 97.11846.7 625 Slaters Lane Alexandria, VA 22314-1176 (US) Publication Classification (73) Assignee: NYCOMED IMAGING AS (51) Int. Cl." .......................... A61K 49/00; A61K 48/00 (52) U.S. Cl. ............................................. 424/9.52; 514/44 (21) Appl. No.: 09/765,614 (22) Filed: Jan. 22, 2001 (57) ABSTRACT Related U.S. Application Data Targetable diagnostic and/or therapeutically active agents, (63) Continuation of application No. 08/960,054, filed on e.g. ultrasound contrast agents, having reporters comprising Oct. 29, 1997, now patented, which is a continuation gas-filled microbubbles stabilized by monolayers of film in-part of application No. 08/958,993, filed on Oct.
    [Show full text]
  • Federal Register / Vol. 60, No. 80 / Wednesday, April 26, 1995 / Notices DIX to the HTSUS—Continued
    20558 Federal Register / Vol. 60, No. 80 / Wednesday, April 26, 1995 / Notices DEPARMENT OF THE TREASURY Services, U.S. Customs Service, 1301 TABLE 1.ÐPHARMACEUTICAL APPEN- Constitution Avenue NW, Washington, DIX TO THE HTSUSÐContinued Customs Service D.C. 20229 at (202) 927±1060. CAS No. Pharmaceutical [T.D. 95±33] Dated: April 14, 1995. 52±78±8 ..................... NORETHANDROLONE. A. W. Tennant, 52±86±8 ..................... HALOPERIDOL. Pharmaceutical Tables 1 and 3 of the Director, Office of Laboratories and Scientific 52±88±0 ..................... ATROPINE METHONITRATE. HTSUS 52±90±4 ..................... CYSTEINE. Services. 53±03±2 ..................... PREDNISONE. 53±06±5 ..................... CORTISONE. AGENCY: Customs Service, Department TABLE 1.ÐPHARMACEUTICAL 53±10±1 ..................... HYDROXYDIONE SODIUM SUCCI- of the Treasury. NATE. APPENDIX TO THE HTSUS 53±16±7 ..................... ESTRONE. ACTION: Listing of the products found in 53±18±9 ..................... BIETASERPINE. Table 1 and Table 3 of the CAS No. Pharmaceutical 53±19±0 ..................... MITOTANE. 53±31±6 ..................... MEDIBAZINE. Pharmaceutical Appendix to the N/A ............................. ACTAGARDIN. 53±33±8 ..................... PARAMETHASONE. Harmonized Tariff Schedule of the N/A ............................. ARDACIN. 53±34±9 ..................... FLUPREDNISOLONE. N/A ............................. BICIROMAB. 53±39±4 ..................... OXANDROLONE. United States of America in Chemical N/A ............................. CELUCLORAL. 53±43±0
    [Show full text]