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Minutes of the CHMP Meeting 14-17 September 2020
13 January 2021 EMA/CHMP/625456/2020 Corr.1 Human Medicines Division Committee for medicinal products for human use (CHMP) Minutes for the meeting on 14-17 September 2020 Chair: Harald Enzmann – Vice-Chair: Bruno Sepodes Disclaimers Some of the information contained in these minutes is considered commercially confidential or sensitive and therefore not disclosed. With regard to intended therapeutic indications or procedure scopes listed against products, it must be noted that these may not reflect the full wording proposed by applicants and may also vary during the course of the review. Additional details on some of these procedures will be published in the CHMP meeting highlights once the procedures are finalised and start of referrals will also be available. Of note, these minutes are a working document primarily designed for CHMP members and the work the Committee undertakes. Note on access to documents Some documents mentioned in the minutes cannot be released at present following a request for access to documents within the framework of Regulation (EC) No 1049/2001 as they are subject to on- going procedures for which a final decision has not yet been adopted. They will become public when adopted or considered public according to the principles stated in the Agency policy on access to documents (EMA/127362/2006). 1 Addition of the list of participants Official address Domenico Scarlattilaan 6 ● 1083 HS Amsterdam ● The Netherlands Address for visits and deliveries Refer to www.ema.europa.eu/how-to-find-us Send us a question Go to www.ema.europa.eu/contact Telephone +31 (0)88 781 6000 An agency of the European Union © European Medicines Agency, 2020. -
Cloud Fonts in Microsoft Office
APRIL 2019 Guide to Cloud Fonts in Microsoft® Office 365® Cloud fonts are available to Office 365 subscribers on all platforms and devices. Documents that use cloud fonts will render correctly in Office 2019. Embed cloud fonts for use with older versions of Office. Reference article from Microsoft: Cloud fonts in Office DESIGN TO PRESENT Terberg Design, LLC Index MICROSOFT OFFICE CLOUD FONTS A B C D E Legend: Good choice for theme body fonts F G H I J Okay choice for theme body fonts Includes serif typefaces, K L M N O non-lining figures, and those missing italic and/or bold styles P R S T U Present with most older versions of Office, embedding not required V W Symbol fonts Language-specific fonts MICROSOFT OFFICE CLOUD FONTS Abadi NEW ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 01234567890 Abadi Extra Light ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 01234567890 Note: No italic or bold styles provided. Agency FB MICROSOFT OFFICE CLOUD FONTS ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 01234567890 Agency FB Bold ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 01234567890 Note: No italic style provided Algerian MICROSOFT OFFICE CLOUD FONTS ABCDEFGHIJKLMNOPQRSTUVWXYZ 01234567890 Note: Uppercase only. No other styles provided. Arial MICROSOFT OFFICE CLOUD FONTS ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 01234567890 Arial Italic ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 01234567890 Arial Bold ABCDEFGHIJKLMNOPQRSTUVWXYZ abcdefghijklmnopqrstuvwxyz 01234567890 Arial Bold Italic ABCDEFGHIJKLMNOPQRSTUVWXYZ -
UAX #44: Unicode Character Database File:///D:/Uniweb-L2/Incoming/08249-Tr44-3D1.Html
UAX #44: Unicode Character Database file:///D:/Uniweb-L2/Incoming/08249-tr44-3d1.html Technical Reports L2/08-249 Working Draft for Proposed Update Unicode Standard Annex #44 UNICODE CHARACTER DATABASE Version Unicode 5.2 draft 1 Authors Mark Davis ([email protected]) and Ken Whistler ([email protected]) Date 2008-7-03 This Version http://www.unicode.org/reports/tr44/tr44-3.html Previous http://www.unicode.org/reports/tr44/tr44-2.html Version Latest Version http://www.unicode.org/reports/tr44/ Revision 3 Summary This annex consolidates information documenting the Unicode Character Database. Status This is a draft document which may be updated, replaced, or superseded by other documents at any time. Publication does not imply endorsement by the Unicode Consortium. This is not a stable document; it is inappropriate to cite this document as other than a work in progress. A Unicode Standard Annex (UAX) forms an integral part of the Unicode Standard, but is published online as a separate document. The Unicode Standard may require conformance to normative content in a Unicode Standard Annex, if so specified in the Conformance chapter of that version of the Unicode Standard. The version number of a UAX document corresponds to the version of the Unicode Standard of which it forms a part. Please submit corrigenda and other comments with the online reporting form [Feedback]. Related information that is useful in understanding this annex is found in Unicode Standard Annex #41, “Common References for Unicode Standard Annexes.” For the latest version of the Unicode Standard, see [Unicode]. For a list of current Unicode Technical Reports, see [Reports]. -
Unicode Request for Cyrillic Modifier Letters Superscript Modifiers
Unicode request for Cyrillic modifier letters L2/21-107 Kirk Miller, [email protected] 2021 June 07 This is a request for spacing superscript and subscript Cyrillic characters. It has been favorably reviewed by Sebastian Kempgen (University of Bamberg) and others at the Commission for Computer Supported Processing of Medieval Slavonic Manuscripts and Early Printed Books. Cyrillic-based phonetic transcription uses superscript modifier letters in a manner analogous to the IPA. This convention is widespread, found in both academic publication and standard dictionaries. Transcription of pronunciations into Cyrillic is the norm for monolingual dictionaries, and Cyrillic rather than IPA is often found in linguistic descriptions as well, as seen in the illustrations below for Slavic dialectology, Yugur (Yellow Uyghur) and Evenki. The Great Russian Encyclopedia states that Cyrillic notation is more common in Russian studies than is IPA (‘Transkripcija’, Bol’šaja rossijskaja ènciplopedija, Russian Ministry of Culture, 2005–2019). Unicode currently encodes only three modifier Cyrillic letters: U+A69C ⟨ꚜ⟩ and U+A69D ⟨ꚝ⟩, intended for descriptions of Baltic languages in Latin script but ubiquitous for Slavic languages in Cyrillic script, and U+1D78 ⟨ᵸ⟩, used for nasalized vowels, for example in descriptions of Chechen. The requested spacing modifier letters cannot be substituted by the encoded combining diacritics because (a) some authors contrast them, and (b) they themselves need to be able to take combining diacritics, including diacritics that go under the modifier letter, as in ⟨ᶟ̭̈⟩BA . (See next section and e.g. Figure 18. ) In addition, some linguists make a distinction between spacing superscript letters, used for phonetic detail as in the IPA tradition, and spacing subscript letters, used to denote phonological concepts such as archiphonemes. -
IJRESS19-August2020
International Journal of Research in Economics and Social Sciences(IJRESS) Available online at: http://euroasiapub.org Vol. 10 Issue 8, August- 2020 ISSN(o): 2249-7382 | Impact Factor: 7.077 | (An open access scholarly, peer-reviewed, interdisciplinary, monthly, and fully refereed journal.) Importance of the number 0 and names for the number 0 in English Umarova Go’zalxon Teacher, Kokand State Pedagogical Institute, Uzbekistan Abdullayeva Marifatxon Teacher, Faculty of Preschool and Primary Education Annotatsiya: Maqolada 0 raqimining etimologiyasi, osiyodan yevropaga kirib kelishi, matematika va matematikadan boshqa fanlarga, yil jadvalida nol raqamining ahamiyati haqida fikr yuritiladi. Kalit so’zlar: ṣifr, matematik termin, kalkulyator, rim, arab raqamlari, elementar algebra Annotation: The article discusses the etymology of the number 0, its entry from Asia to Europe, the importance of the number zero in the table of the year, from mathematics and non-mathematics to other disciplines. Keywords: ṣifr, mathematical term, calculator, Roman, Arabic numerals, elementary algebra Аннотация: В статье обсуждается этимология числа 0, его проникновение из Азии в Европу, важность числа ноль в таблице года, от математики и нематематики до других дисциплин. Ключевые слова: ifr, математический термин, калькулятор, римские, арабские цифры, элементарная алгебра. The word zero came into the English language via French zéro from Italian zero, Italian contraction of Venetian zevero form of Italian zefiro via ṣafira or ṣifr.In pre-Islamic time the word ṣifr had the meaning "empty". Sifr evolved to mean zero when it was used to translate śūnya Sanskrit from India. The first known English use of zero was in 1598.[1]Depending on the context, there may be different words used for the number zero. -
Technical Reference Manual for the Standardization of Geographical Names United Nations Group of Experts on Geographical Names
ST/ESA/STAT/SER.M/87 Department of Economic and Social Affairs Statistics Division Technical reference manual for the standardization of geographical names United Nations Group of Experts on Geographical Names United Nations New York, 2007 The Department of Economic and Social Affairs of the United Nations Secretariat is a vital interface between global policies in the economic, social and environmental spheres and national action. The Department works in three main interlinked areas: (i) it compiles, generates and analyses a wide range of economic, social and environmental data and information on which Member States of the United Nations draw to review common problems and to take stock of policy options; (ii) it facilitates the negotiations of Member States in many intergovernmental bodies on joint courses of action to address ongoing or emerging global challenges; and (iii) it advises interested Governments on the ways and means of translating policy frameworks developed in United Nations conferences and summits into programmes at the country level and, through technical assistance, helps build national capacities. NOTE The designations employed and the presentation of material in the present publication do not imply the expression of any opinion whatsoever on the part of the Secretariat of the United Nations concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries. The term “country” as used in the text of this publication also refers, as appropriate, to territories or areas. Symbols of United Nations documents are composed of capital letters combined with figures. ST/ESA/STAT/SER.M/87 UNITED NATIONS PUBLICATION Sales No. -
WG2 M52 Minutes
ISO.IEC JTC 1/SC 2 N____ ISO/IEC JTC 1/SC 2/WG 2 N3603 2009-07-08 ISO/IEC JTC 1/SC 2/WG 2 Universal Multiple-Octet Coded Character Set (UCS) - ISO/IEC 10646 Secretariat: ANSI DOC TYPE: Meeting Minutes TITLE: Unconfirmed minutes of WG 2 meeting 54 Room S206/S209, Dublin Centre University, Dublin, Ireland 2009-04-20/24 SOURCE: V.S. Umamaheswaran, Recording Secretary, and Mike Ksar, Convener PROJECT: JTC 1.02.18 – ISO/IEC 10646 STATUS: SC 2/WG 2 participants are requested to review the attached unconfirmed minutes, act on appropriate noted action items, and to send any comments or corrections to the convener as soon as possible but no later than the Due Date below. ACTION ID: ACT DUE DATE: 2009-10-12 DISTRIBUTION: SC 2/WG 2 members and Liaison organizations MEDIUM: Acrobat PDF file NO. OF PAGES: 60 (including cover sheet) Michael Y. Ksar Convener – ISO/IEC/JTC 1/SC 2/WG 2 22680 Alcalde Rd Phone: +1 408 255-1217 Cupertino, CA 95014 Email: [email protected] U.S.A. ISO International Organization for Standardization Organisation Internationale de Normalisation ISO/IEC JTC 1/SC 2/WG 2 Universal Multiple-Octet Coded Character Set (UCS) ISO/IEC JTC 1/SC 2 N____ ISO/IEC JTC 1/SC 2/WG 2 N3603 2009-07-08 Title: Unconfirmed minutes of WG 2 meeting 54 Room S206/S209, Dublin Centre University, Dublin, Ireland; 2009-04-20/24 Source: V.S. Umamaheswaran ([email protected]), Recording Secretary Mike Ksar ([email protected]), Convener Action: WG 2 members and Liaison organizations Distribution: ISO/IEC JTC 1/SC 2/WG 2 members and liaison organizations 1 Opening Input document: 3573 2nd Call Meeting # 54 in Dublin; Mike Ksar; 2009-02-16 Mr. -
Diphalane/Sedimonthole 2017
SOUTH AFRICAN SOCIAL ATTITUDES SURVEY Questionnaire 3: Diphalane/Sedimonthole 2017 BAARABI BA DINGWAGA DI LE 16 GO YA KWA GODIMO + Dumelang. Ke nna __________ re dira dipatlisiso mo boemong jwa Lekgotla la Dipatlisiso tsa Sematlhale a Setho (HSRC). Lekgotla la HSRC le dira dipatlisiso tsa dikakanyo mo setšhabeng sa Aforika Borwa ka gale. Dikgangkgolo di akaretsa dipuisano, polotiki, thuto, botlhoka tiro, mathata a bagodi le kamano magareng ga ditlhopha. Go leka go latedisisa tiro e e dirilweng mo nakong e e fetileng, re rata go botsa dipotso mo dintlheng tse di farologaneng tse di leng botlhokwa mo nageng e. Gore re bone tshedimosetso ya sematlhale, ya botshepegi, re kopa gore o arabe dipotso tse di lateng ka botshepegi jo bo kgonegang. Dikakanyo tsa gago di botlhokwa mo dipatlisisong tse. Lefelo le o nnang mo go lone ga mmogo le wena le kgethetswe dipatlisiso tse go sa dirisiwe tatelano e pe. Ke fela ka lesego gore o be o tlhophilwe. Tshedimosetso e o e re nayang e tla tsewa jaaka khupamarama. Wena le ba lelapa la gago ga lo kitla le lemogiwa ka leina kgotsa aterese mo dipegong tse re ikaelelang go di kwala. PARTICULARS OF VISITS TIME TIME DAY MONTH **RESPONSE STARTED COMPLETED HR MIN HR MIN First visit / / 2017 Second visit / / 2017 Third visit / / 2017 **RESPONSE CODES Completed questionnaire = 01 Partially completed questionnaire (specify reason) = 02 Revisit Appointment made = 03 Selected respondent not at home = 04 No one home = 05 Do not qualify Vacant house/flat/stand/not a house or flat/demolished = 06 No person qualifies according to the survey specifications = 07 Respondent cannot communicate with interviewer because of language = 08 Respondent is physically/mentally not fit to be interviewed = 09 Refusals Contact person refused = 10 Interview refused by selected respondent = 11 Interview refused by parent = 12 Interview refused by other household member = 13 OFFICE USE = 14 STRICTLY CONFIDENTIAL i Name of Interviewer ……………………………………………………………………………….……………. -
Web Typography │ 2 Table of Content
Imprint Published in January 2011 Smashing Media GmbH, Freiburg, Germany Cover Design: Ricardo Gimenes Editing: Manuela Müller Proofreading: Brian Goessling Concept: Sven Lennartz, Vitaly Friedman Founded in September 2006, Smashing Magazine delivers useful and innovative information to Web designers and developers. Smashing Magazine is a well-respected international online publication for professional Web designers and developers. Our main goal is to support the Web design community with useful and valuable articles and resources, written and created by experienced designers and developers. ISBN: 978-3-943075-07-6 Version: March 29, 2011 Smashing eBook #6│Getting the Hang of Web Typography │ 2 Table of Content Preface The Ails Of Typographic Anti-Aliasing 10 Principles For Readable Web Typography 5 Principles and Ideas of Setting Type on the Web Lessons From Swiss Style Graphic Design 8 Simple Ways to Improve Typography in Your Designs Typographic Design Patterns and Best Practices The Typography Dress Code: Principles of Choosing and Using Typefaces Best Practices of Combining Typefaces Guide to CSS Font Stacks: Techniques and Resources New Typographic Possibilities with CSS 3 Good Old @Font-Face Rule Revisted The Current Web Font Formats Review of Popular Web Font Embedding Services How to Embed Web Fonts from your Server Web Typography – Work-arounds, Tips and Tricks 10 Useful Typography Tools Glossary The Authors Smashing eBook #6│Getting the Hang of Web Typography │ 3 Preface Script is one of the oldest cultural assets. The first attempts at written expressions date back more than 5,000 years ago. From the Sumerians cuneiform writing to the invention of the Gutenberg printing press in Medieval Germany up to today՚s modern desktop publishing it՚s been a long way that has left its impact on the current use and practice of typography. -
Sacred Concerto No. 6 1 Dmitri Bortniansky Lively Div
Sacred Concerto No. 6 1 Dmitri Bortniansky Lively div. Sla va vo vysh nikh bo gu, sla va vo vysh nikh bo gu, sla va vo Sla va vo vysh nikh bo gu, sla va vo vysh nikh bo gu, 8 Sla va vo vysh nikh bo gu, sla va, Sla va vo vysh nikh bo gu, sla va, 6 vysh nikh bo gu, sla va vovysh nikh bo gu, sla va vovysh nikh sla va vo vysh nikh bo gu, sla va vovysh nikh bo gu, sla va vovysh nikh 8 sla va vovysh nikh bo gu, sla va vovysh nikh bo gu sla va vovysh nikh bo gu, sla va vovysh nikh bo gu 11 bo gu, i na zem li mir, vo vysh nikh bo gu, bo gu, i na zem li mir, sla va vo vysh nikh, vo vysh nikh bo gu, i na zem 8 i na zem li mir, i na zem li mir, sla va vo vysh nikh, vo vysh nikh bo gu, i na zem i na zem li mir, i na zem li mir 2 16 inazem li mir, sla va vo vysh nikh, vo vysh nikh bo gu, inazem li mir, i na zem li li, i na zem li mir, sla va vo vysh nikh bo gu, i na zem li 8 li, inazem li mir, sla va vo vysh nikh, vo vysh nikh bo gu, i na zem li, ina zem li mir, vo vysh nikh bo gu, i na zem li 21 mir, vo vysh nikh bo gu, vo vysh nikh bo gu, i na zem li mir, i na zem li mir, vo vysh nikh bo gu, vo vysh nikh bo gu, i na zem li mir, i na zem li 8 mir, i na zem li mir, i na zem li mir, i na zem li, i na zem li mir,mir, i na zem li mir, i na zem li mir, inazem li, i na zem li 26 mir, vo vysh nikh bo gu, i na zem li mir. -
5892 Cisco Category: Standards Track August 2010 ISSN: 2070-1721
Internet Engineering Task Force (IETF) P. Faltstrom, Ed. Request for Comments: 5892 Cisco Category: Standards Track August 2010 ISSN: 2070-1721 The Unicode Code Points and Internationalized Domain Names for Applications (IDNA) Abstract This document specifies rules for deciding whether a code point, considered in isolation or in context, is a candidate for inclusion in an Internationalized Domain Name (IDN). It is part of the specification of Internationalizing Domain Names in Applications 2008 (IDNA2008). Status of This Memo This is an Internet Standards Track document. This document is a product of the Internet Engineering Task Force (IETF). It represents the consensus of the IETF community. It has received public review and has been approved for publication by the Internet Engineering Steering Group (IESG). Further information on Internet Standards is available in Section 2 of RFC 5741. Information about the current status of this document, any errata, and how to provide feedback on it may be obtained at http://www.rfc-editor.org/info/rfc5892. Copyright Notice Copyright (c) 2010 IETF Trust and the persons identified as the document authors. All rights reserved. This document is subject to BCP 78 and the IETF Trust's Legal Provisions Relating to IETF Documents (http://trustee.ietf.org/license-info) in effect on the date of publication of this document. Please review these documents carefully, as they describe your rights and restrictions with respect to this document. Code Components extracted from this document must include Simplified BSD License text as described in Section 4.e of the Trust Legal Provisions and are provided without warranty as described in the Simplified BSD License. -
Typotheque Elementar
Typotheque type specimen & OpenType feature specification. Please read before using the fonts. OpenType font family supporting Latin based European Elementar Std languages, with extensive typographic features. AB — Western European (1252 Latin 1) — Central European (1250 Latin 2) — Baltic (1257) — Turkish (1254) Designed by Gustavo Ferreira, 2002-2011 OpenType features in Elementar hiztvsgfq What is OpenType? OpenType is a cross-platform font format developed by Adobe and Microsoft. It has a potential to provide advanced typographic features such as multilingual character sets, ligatures, small capitals, various numeral styles, and contextual substitutions. OpenType, as the new industry standard, supports Unicode, which enables the fonts to contain a large number of characters. While PostScript fonts are a technically limited to a maximum of only 256 characters, OpenType fonts can have more than 65,000 glyphs. This means that a user does not need to have separate fonts for Western, Central European, Baltic, Cyrillic or Greek languages, but could have one single file which supports all these encodings. OpenType fonts work in all applications, however only some applications take advantage of the advanced OpenType features. Other applications will only use the first 256 characters. For more about OpenType information go to www.typotheque. com/opentype © 2011, Typotheque.com. For information purposes only. complete character set © 2011, Typotheque.com. For information purposes only. © 2011, Typotheque.com. For information purposes only. © 2011, Typotheque.com. For information purposes only. About the Font Elementar is a parametric font system designed to bring more typographic flexibility to digital screens. Elementar embraces and explores the unique properties of digital media: the pixel, the coarse resolution grid, and the dimension of time.