Anti-Kell (Aa 1-732) Polyclonal Antibody (DBGA- 0203) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-Kell (aa 1-732) polyclonal antibody (DBGA- 0203) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse polyclonal to Blood Group Kell Antigen

Antigen Description The Kell antigen system (also known as Kell-Cellano system) is a group of antigens on the human red blood cell surface which are important determinants of blood type and are targets for autoimmune or alloimmune diseases which destroy red blood cells. Kell can be noted as K, k, or Kp. The Kell antigens are peptides found within the Kell protein, a 93 kilodalton transmembrane zinc-dependent endopeptidase which is responsible for cleaving endothelin-3.

Target Kell

Immunogen Full length protein corresponding to Human Blood Group Kell Antigen aa 1-732. Sequence: MEGGDQSEEEPRERSQAGGMGTLWSQESTPEERLPVEGSR PWAVARRVLTAILILGLLLCFSVLLFYNFQNCGPRPCETS VCLDLRDHYLASGNTSVAPCTDFFSFACGRAKETNNSFQE LATKNKNRLRRILEVQNSWHPGSGEEKAFQFYNSCMDTLA IEAAGTGPLRQVIEELGGWRISGKWTSLNFNRTLRLLMSQ YGHFPFFRAYLGPHPASPHTPVIQIDQPEFDVPLKQDQEQ KIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITS RLFQFLRPLEQRRAQGKLFQMVTIDQLKEMAPAIDWLSCL QATFTPMSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQRDF LQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPP

Isotype IgG

Source/Host Mouse

Species Reactivity Human

Purification Whole antiserum

Conjugate Unconjugated

Applications WB

Sequence Similarities Belongs to the peptidase M13 family.

Cellular Localization Cell membrane. Spans the erythrocyte membrane, and is attached to the underlying

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Positive Control Blood Group Kell Antigen-transfected 293T cell lysate

Procedure Blood Group Antibodies

Format Liquid

Size 50 ul

Preservative None

Storage Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]