Supporting Information
Figure S1. The functionality of the tagged Arp6 and Swr1 was confirmed by monitoring cell growth and sensitivity to hydeoxyurea (HU). Five-fold serial dilutions of each strain were plated on YPD with or without 50 mM HU and incubated at 30°C or 37°C for 3 days.
Figure S2. Localization of Arp6 and Swr1 on chromosome 3. The binding of Arp6-FLAG (top), Swr1-FLAG (middle), and Arp6-FLAG in swr1 cells (bottom) are compared. The position of Tel 3L, Tel 3R, CEN3, and the RP gene are shown under the panels.
Figure S3. Localization of Arp6 and Swr1 on chromosome 4. The binding of Arp6-FLAG (top), Swr1-FLAG (middle), and Arp6-FLAG in swr1 cells (bottom) in the whole chromosome region are compared. The position of Tel 4L, Tel 4R, CEN4, SWR1, and RP genes are shown under the panels.
Figure S4. Localization of Arp6 and Swr1 on the region including the SWR1 gene of chromosome 4. The binding of Arp6- FLAG (top), Swr1-FLAG (middle), and Arp6-FLAG in swr1 cells (bottom) are compared. The position and orientation of the SWR1 gene is shown.
Figure S5. Localization of Arp6 and Swr1 on chromosome 5. The binding of Arp6-FLAG (top), Swr1-FLAG (middle), and Arp6-FLAG in swr1 cells (bottom) are compared. The position of Tel 5L, Tel 5R, CEN5, and the RP genes are shown under the panels.
Figure S6. Preferential localization of Arp6 and Swr1 in the 5′ end of genes. Vertical bars represent the binding ratio of proteins in each locus. The binding of Arp6-Flag (Top), Swr1-Flag (middle), and Arp6-Flag in swr1 cells (bottom) in the region 228K-244K of Chr 6R were compared. The orientation of transcription of the genes of Watson strand and Crick strand in the region was shown by arrows in the map over the panels. Regions of divergent promoters are indicated with gray shadow.
Figure S7. Correlation of the localizations of Arp6 and Swr1. The Arp6-binding log2 ratios of Arp6-binding loci (change p- value <0.025) in wild-type (A) and in swr1 cells (B) are represented as scatterplots versus the Swr1 binding log2 ratio in each Arp6 binding locus of wild-type cells. The yellow lines represent the hypothetical pattern of the data if Arp6 and Swr1 bind equally on the chromosomes.
Figure S8. ChIP analysis for Htz1 in cells lacking Arp6 or Swr1. Htz1 association to the promoter of GAL1, SWR1, and ribosomal protein (RPL13A and RPS16B) genes was analyzed using ChIP with an anti-Htz1 antibody (abcam, ab4626) and quantified using real-time quantitative PCR in wild-type (WT), arp6, and swr1 cells. The values are indicated as percentage of input DNA obtained by ChIP with anti-Htz1 antibody. The data points represent the mean ± SD for at least three independent experiments.
Figure S9. Quantitative analysis of RDS1 (YCR106W) and UBX3 (YDL091C) in arp6- and htz1-deletion mutants. The same amount of total RNA from wild-type, arp6, and htz1 cells was analyzed using real-time quantitative RT–PCR. The ACT1 gene was analyzed as a control. The relative amount of the transcript of the genes to ACT1 is shown. The data points represent the mean ± SD for at least three independent experiments.
Figure S10. ChIP analysis for nuclear pore complex with GAL1 gene in arp6 cells. The association of GAL1 gene with NPC was analyzed using ChIP with an antibody against nuclear pore complex proteins (Mab414, abcam, ab24609) in wild-type (WT) and arp6 cells grown on the glucose- or galactose containing media. Immunoprecipitated DNA was quantified using real-time PCR probed for GAL1 gene. The percentage of recovered DNA over input is plotted relative to wild-type cells on glucose as 1. The data points represent the mean ± SD for at least three independent experiments.
Table S1. Presence of Arp6 in nonrepetitive 10 kb subtelomere zones. (0.05 MB DOC)
Table S2. Microarray analysis in arp6Δ and swr1Δ cells. (1.10 MB XLS)
Table S3. Binding of Arp6 and Swr1 on ribosomal protein genes. (0.04 MB DOC)
Table S4. Expression of RP genes in arp6Δ and swr1Δ cells. (0.04 MB XLS)
Table S5. Genes markedly down-regulated in arp6 cells. (0.09 MB DOC)
Table S6. Strains used in this study. (0.06 MB DOC)
Text S1. Primer sequences. (0.04 MB DOC)
SWR1
Arp6
Swr1
Arp6 in swr1
Yoshida et al., Supplementary Fig. S3B
Arp6
Swr1
Arp6 in swr1
Yoshida et al., Supplementary Fig. S5 A Arp6 (log2) 4
3.5
3
2.5 r =0.278, n=2001 2
1.5
1
0.5
0 -2-101234567 Swr1 (log2)
B Arp6 in swr1 (log2)
4
3.5
3
2.5
2 r =0.138, n=1463 1.5
1
0.5
0 -2-101234567 Swr1 (log2)
Yoshida et al., Supplementary Fig. S6 ChIP analysis for Htz1 in arp6 and swr1 mutants
5 WT arp6 4 swr1
3
2
1 % precipitated by anti-Htz1 / input
0 GAL1 SWR1 RPL13A RPS16B
Yoshida et al. Supplementary Fig. S7 Quantitative rtPCR for Arp6/Swr1-bound genes
(x10- 3 ) 8 WT arp6 htz1
ACT1 6
4
2 Relative expression to
0 RDS1 UBX3
Yoshida et al., Supplementary Fig. S8 ChIP for GAL1-nuclear pore association
p<0.05 2.0 WT arp6
1.5
1.0 % (IP/ input) / WT gluc
0.5
0 glucose galactose
Yoshida et al., Supplementary Fig. S9 Supplementary Table S1. Presence of Arp6 in nonrepetitive 10 kb subtelomere zones
Chr3L (32)1) Chr4L (4) Chr5L (15) Chr6R (34) Total (145) Chr3R (34) Chr4R (13) Chr5R (13)
12) (3%)3) 1 (25%) 3 (20%) Arp6 binding loci 7 (21%) 16 (11%) 3 (9%) 1 (8%) 0 (0%) SWR1 coincidence with 0 (0%) 0 (0%) 2 (13%) 2 (6%) 7 (5%) Swr1 binding 3 (9%) 0 (0%) 0 (0%)
3 (9%) 0 (0%) 0 (0%) swr1 Arp6 binding loci 9 (26%) 22 (15%) 4 (12%) 5 (38%) 1 (8%)
1) number of subtelomeric probes in the array, 2) number of probes on which the ChIP-chip signal is significantly positive, 3) percentage of binding-positive probes
SupplemantaTable S2
arp6 swr1 arp6 log2 ratio swr1 log2 ratio t-test p-value t-test p-value
YAL001C -0.48778725 0.055121132 -0.651383868 0.009641293 TFC3 transcription factor tau (TFIIIC) subunit 138 Vps8p is a membrane-associated hydrophilic protein which contains a C-terminal cysteine-rich region that conforms to the H2 variant of the YAL002W -0.50137568 0.02012999 0.465583742 0.134286021 VPS8 RING finger Zn2+ binding motif. YAL003W 0.291356151 0.57828274 0.018063402 0.741564133 EFB1 Translation elongation factor EF-1beta, GDP/GTP exchange factor for Tef1p/Tef2p YAL004W -1.37471567 0.023223502 0.446599197 0.094749311 strong similarity to A.klebsiana glutamate dehydrogenase YAL007C 0.514959137 0.367907397 0.193498974 0.126415188 ERP2 p24 protein involved in membrane trafficking YAL008W -1.07248083 0.003902375 0.04877654 0.757249306 FUN14 hypothetical protein YAL009W -0.83886578 0.039587079 -0.007318718 0.898104961 SPO7 sporulation protein YAL010C 0.350119155 0.079737228 -0.110610526 0.32107038 MDM10 Mitochondrial outer membrane protein involved in mitochondrial morphology and inheritance YAL011W -0.34259393 0.310843521 -0.299325162 0.15316135 possible mitochondrial transit peptide/weak similarity to Mus musculus p53-associated cellular protein YAL012W 1.573242516 0.034945842 0.519382719 0.240287741 CYS3 cystathionine gamma-lyase YAL013W 0.10593589 0.260657892 0.288869805 0.318643395 DEP1 regulation of phospholipid metabolism YAL014C 0.190903734 0.569458913 0.169774313 0.044229011 hypothetical protein YAL015C 0.370541536 0.031276471 -0.245836227 0.004561835 NTG1 DNA glycosylase YAL016W -0.64975335 0.0560383 0.036635636 0.638828131 TPD3 protein phosphatase 2A regulatory subunit A YAL017W -1.25829846 0.004518805 0.126513184 0.38324032 FUN31 Serine/threonine kinase YAL018C -0.51051588 0.164932688 -0.264509297 0.317542105 3 transmembrane domains/weak similarity to hypothetical proteins YOL047c and YOL048c YAL019W 0.320792247 0.444493655 -0.211820784 0.280255331 FUN30 SNF2 protein family YAL021C -0.1074359 0.778044634 -0.008790493 0.798167731 CCR4 95 kDa containng leucine rich tandem repeats YAL022C 0.656687352 0.001364239 0.428924658 0.115624767 FUN26 predicted membrane protein YAL023C 0.778388229 0.117515196 0.53048886 0.106271155 PMT2 dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase YAL024C 0.327596538 0.491315967 0.065792226 0.797949412 LTE1 putative GTP-exchange protein YAL025C 1.742728628 0.005475432 -0.503643316 0.197141618 MAK16 putative nuclear protein YAL026C -0.15225171 0.144316487 0.062776186 0.624950436 DRS2 Membrane-spanning Ca-ATPase (P-type),member of the cation transport (E1-E2) ATPases YAL027W -0.19310171 0.23325453 -0.364863449 0.173323366 hypothetical protein YAL028W -1.05821689 0.028312621 -0.12586505 0.263146998 similarity to hypothetical protein YOR324c YAL029C 1.414871688 0.169872272 0.17340552 0.14232505 MYO4 myosin YAL030W -0.82724505 0.037223546 0.300700811 0.135945922 SNC1 homolog of Snc2p, vesicle-associated membrane protein (synaptobrevin) homolog, forms a complex with Snc2p and Sec9p YAL031C -0.66093199 0.001932142 0.091597547 0.555114187 FUN21 FUN21 YAL032C -0.45984855 0.100362467 0.119635039 0.26845368 PRP45 pre-mRNA splicing factor YAL033W 0.516623095 0.085119298 -0.332318037 0.10772256 POP5 An integral subunit of RNase P and apparent subunit of RNase MRP YAL034C -1.37859175 0.009174568 0.462426647 0.033887391 FUN19 Function unknown now YAL034W-A 0.046056852 0.601311241 -0.173771005 0.501575118 MTW1 determining metaphase spindle length YAL035C-A 0.455896607 0.408337787 0.428415177 0.170295679 YAL035W 0.75438664 0.04599226 -0.221359802 0.054514118 FUN12 97 kDa protein YAL036C 1.239106861 0.048698109 0.063806118 0.17119679 FUN11 similar to Xenopus GTP-binding protein DRG YAL037W -0.57645571 0.009922233 -0.165687374 0.532682496 strong similarity to GTP-binding proteins YAL038W 0.891293531 0.223803982 0.838341102 0.122662277 CDC19 Pyruvate kinase YAL039C 0.367285033 0.377663351 0.193111406 0.48023897 CYC3 cytochrome c heme lyase (CCHL) YAL040C -0.19482503 0.251202381 0.567158599 0.138150953 CLN3 G(sub)1 cyclin YAL041W 0.121678523 0.623119848 0.001064527 0.995446938 CDC24 Guanine nucleotide exchange factor (a.k.a. GDP-release factor) for cdc42 YAL042W 0.520759379 0.112442757 0.121088992 0.106200684 ERV46 ER-Golgi transport vesicle protein YAL043C -0.09940515 0.785189261 0.642208033 0.063435676 PTA1 pre-tRNA processing YAL043C-A 0.364729879 0.471390403 0.118430232 0.175428015 YAL044C 1.22688802 0.213909953 0.359553331 0.125672906 GCV3 H-protein subunit of the glycine cleavage system YAL045C -0.15640282 0.262645106 0.601851976 0.070209367 hypothetical protein YAL047C -0.19449606 0.6792255 -0.488173264 0.134349146 SPC72 component of spindle pole bodies YAL048C -0.53508764 0.050309883 0.083250034 0.159663585 PEP4 vacuolar aspartic proteasse YAL049C -1.58912253 0.000295413 0.155651056 0.32049334 weak similarity to Legionella small basic protein sbpA YAL053W 1.167219198 0.23272621 0.494264836 0.182351238 strong similarity to hypothetical proteins YOR365c,YGL139w,YPL221w YAL054C -1.09564458 0.024545903 0.245199899 0.445281937 ACS1 inducible acetyl-coenzyme A synthetase YAL055W -1.18899461 0.004853529 -0.410131441 0.074131314 PEX22 peroxisomal matrix protein import YAL058C-A 0.154682303 0.736803287 0.434889949 0.03830118 YAL058W -0.3166379 0.01219009 0.124089103 0.085005861 CNE1 Calnexin and calreticulin homolog YAL059W 1.189087482 0.105757458 -0.368382138 0.180043241 ECM1 putative transmembrane domain protein involved in cell wall biogenesis YAL060W -0.33257326 0.461367286 0.208542234 0.398809867 FUN49 stereospecific (2R, 3R)-2,3-butanediol dehydrogenase YAL061W -1.7629215 0.014135456 0.322907683 0.261242406 FUN50 similarity to alcohol/sorbitol dehydrogenase YAL062W -1.71445039 0.006829855 0.056824429 0.427171159 GDH3 NADP-linked glutamate dehydrogenase YAL064C-A -0.1786571 0.740798376 0.233634589 0.382026263 strong similarity to Flo1p, Flo5p - putative pseudogene YAL064W -0.74505863 0.145378609 0.286819838 0.453965863 hypothetical protein YAL065C -1.17547087 0.003827097 0.399871097 0.081840231 strong similarity to Flo1p and Flo9p - putative pseudogene YAL066W -0.93408152 0.296857989 -0.005238039 0.9931692 weak similarity to membrane protein yybF - Bacillus subtilis YAL067C -1.2512459 0.039595582 -0.066498241 0.541023311 SEO1 putative permease/Suppressor of Sulfoxyde Ethionine resistance YAL069W -0.14723693 0.771200929 0.404281405 0.099211952 YAR002C-A 0.8089258 0.349749522 0.258873046 0.277899274 ERP1 p24 protein involved in membrane trafficking YAR002W 1.036070284 0.005377987 -0.125110616 0.316508824 NUP60 nuclear pore protein YAR003W -0.21157782 0.286119875 -0.439692436 0.028854891 FUN16 beta transducin domain/similarity to human RB protein binding protein YAR007C 0.63060681 0.128060752 0.193886043 0.236505966 RFA1 69 kDa subunit of the heterotrimeric RPA (RF-A) single-stranded DNA binding protein, binds URS1 and CAR1 YAR008W 0.531614843 0.249599706 0.007320805 0.966485591 SEN34 34kDa subunit of the tetrameric tRNA splicing endonuclease YAR009C 1.568985076 0.048845245 0.323389091 0.027024819 TY1B Ty1B protein YAR010C 1.440334364 0.067113503 0.4556637 0.009967175 TY1A TY1A protein YAR014C 0.68765935 0.06094559 -0.116161101 0.246966 BUD14 maximal growth/similarity to hypothetical protein S.pombe YAR015W 1.028246324 0.28042917 -0.063672942 0.498936214 ADE1 phosphoribosyl amino imidazolesuccinocarbozamide synthetase YAR018C 0.244945801 0.50654314 0.208883698 0.000210337 KIN3 protein kinase YAR019C -0.17792809 0.554620603 0.344762613 0.202010355 CDC15 protein kinase domain YAR020C 0.150018392 0.566814473 0.644597596 0.018234699 PAU7 similar to Pau3, member of Pau1 family YAR023C -0.63998255 0.061165085 0.011521673 0.926460784 membrane protein YAR027W -0.69710112 0.111520721 -0.196597495 0.124441656 FUN55 membrane protein/strong similarity to YAR028w, YCR007c, YGL053w, YAR031w, FUN59p and YGL051w YAR028W 0.02438456 0.965511157 0.018670564 0.788749248 membrane protein/strong similarity to Fun55p, YGL053w, YCR007c, YAR031w, Fun59p and YGL051w YAR030C 0.304108258 0.377811936 0.037110257 0.897034717 hypothetical protein YAR031W -0.6089193 0.023134268 -0.059812785 0.68063699 PRM9 membrane protein/strong similarity to YGL053w, Fun59p, YGL051w, Fun55p, YAR028w and YCR007c YAR033W -0.52963824 0.157687557 -0.030386547 0.852864032 FUN59 membrane protein/strong similarity to YGL051w, YGL053w, YAR031w, Fun55p, YAR028w and YCR007c YAR035W -0.07180285 0.912504663 -0.088423459 0.289350854 YAT1 Outer carnitine acetyltransferase, mitochondrial YAR042W -0.03006143 0.924880125 0.283718288 0.419166192 SWH1 ankyrin repeat YAR044W -0.00263468 0.994132468 -0.054374301 0.653312417 OSH1 Shows homology to the human oxysterol binding protein (OSBP) YAR047C -0.86387318 0.264807528 -0.457303432 0.435180037 predicted nuclear targeting signal YAR053W -0.58801994 0.172781392 0.483606121 0.307259816 predicted membrane protein YAR060C 0.132593072 0.858684956 0.077482878 0.674930742 strong similarity to hypothetical protein YHR212c YAR061W -0.49217382 0.264261253 -7.98871E-05 0.99978933 strong similarity to N-terminus of Flo1p - putative pseudogene YAR062W -0.16768339 0.455152005 0.565555252 0.070699921 strong similarity to Flo1p - putative pseudogene YAR064W 0.075841311 0.848648394 0.192771016 0.405714066 Potential membrane protein YAR066W 0.700203408 0.213023476 0.412287539 0.060145965 identical to YHR214w hypothetical protein, similarity to Sta1p YAR068W 0.245010922 0.505026924 0.479488019 0.125500624 Potential membrane protein YAR069C -0.74696325 0.059178657 1.062230426 0.074823538 Potential membrane protein YAR070C -0.05544974 0.578769239 -0.202657858 0.753174965 potential mitochondrial transit peptide YAR071W -0.24993142 0.657840395 0.242156128 0.04763318 PHO11 Acid phosphatase, secreted YAR073W 0.808656429 0.19847315 -0.391364075 0.012098201 IMD1 IMP dehydrogenase homolog YAR075W 1.350080559 0.042146299 0.285653905 0.110292263 strong similarity to IMP dehydrogenases YBL001C 0.521372342 0.063150214 0.377806625 0.007995235 ECM15 involved in cell wall biogenesis YBL002W 0.644046534 0.11247777 0.436611469 0.050795936 HTB2 Histone H2B (HTB1 and HTB2 code for nearly identical proteins) YBL005W-A 0.711706069 0.066631051 0.397034913 0.029499345 TyA gag protein. Gag processing produces capsid proteins. The TyB Gag-Pol protein. Gag processing produces capsid proteins. Pol is cleaved to produce protease, reverse transcriptase, and integrase YBL005W-B 0.806694821 0.004270475 0.44184349 0.099669502 activities. YBL007C -1.05475926 0.011207344 0.585806022 0.060636472 SLA1 contains 3 SH3 domains, interacts with Bee1p YBL008W -0.25713498 0.395843766 -0.291904995 0.082416055 HIR1 putative repressor protein homologous to yeast Tup1p and mammalian retinal transducin ; contains nuclear targeting signal YBL009W 0.377903649 0.410199557 -0.139775549 0.535123179 strong similarity to DNA damage responsive Alk1p YBL011W 0.732695584 0.029991524 0.08310294 0.483247349 SCT1 suppressor of choline-transport mutants YBL012C 0.122002089 0.818084302 0.501228611 0.245672062 questionable ORF YBL013W -0.54551921 0.247361356 -0.131201515 0.688835462 FMT1 Methionyl-tRNA Transformylase YBL014C 0.145227982 0.439522054 -0.259788052 0.108339886 RRN6 member of yeast Pol I core factor (CF) also composed of Rrn11p, Rrn7p and TATA-binding protein YBL015W -1.88887999 0.011757083 -0.089791178 0.380359889 ACH1 acetyl CoA hydrolase YBL016W 0.405385742 0.154177413 0.28688141 0.20783228 FUS3 cdc2+ /CDC28 related kinase with positive role in conjugation YBL017C -0.35057353 0.009578128 0.117031097 0.552092446 PEP1 carboxypeptidase Y sorting receptor in late Golgi ; Type I integral membrane protein 166aa cytoplasmic tail, 1300 aa lumenal domain YBL018C 0.429413309 0.189625608 0.017990194 0.520462645 POP8 integral subunit of RNase P and apparent subunit of RNase MRP YBL019W -0.44360937 0.193112906 0.251108094 0.139099165 APN2 AP endonuclease YBL020W -0.14644714 0.399902983 0.129851451 0.139006802 RFT1 67 kDa integral membrane protein YBL021C 0.418111438 0.094468832 0.244357052 0.122508233 HAP3 transcriptional activator protein of CYC1 YBL022C 0.057851963 0.823243187 -0.158622217 0.282644513 PIM1 mitochondrial ATP-dependent protease YBL023C 0.311056122 0.164045195 -0.186899983 0.230537931 MCM2 Minichromosome maintenance protein, transcription factor YBL024W 0.768176955 0.114518321 -0.234637929 0.036028563 NCL1 Probable proliferating-cell nucleolar antigen (human p120) YBL025W 0.214419035 0.022039086 0.005455163 0.978683975 RRN10 Upstream activation factor subunit YBL026W 0.550467742 0.123592519 -0.418656457 0.061304339 LSM2 snRNA-associated protein of the Sm class YBL027W 1.076896847 0.044605028 -0.188299044 0.495992786 RPL19B Ribosomal protein L19B (YL14) (L23B) (rpl5L) YBL028C 1.508809573 0.098454761 -0.774528492 0.132994667 hypothetical protein - involved in mating-type regulation YBL029W -0.69897514 0.012282849 -0.263262192 0.089300671 hypothetical protein YBL030C -0.9969331 0.023634487 0.172120597 0.083005311 PET9 mitochondrial ADP /ATP translocator YBL031W 0.234498822 0.377257191 -0.008179032 0.96811451 SHE1 hypothetical protein YBL032W -0.38895763 0.045985811 0.017670569 0.957997296 weak similarity to hnRNP complex protein homolog YBR233w YBL033C 0.267094143 0.071552505 -0.124879611 0.137726678 RIB1 GTP cyclohydrolase II YBL034C 0.923515409 0.026769582 -0.020444035 0.486715894 STU1 component of the mitotic spindle YBL035C 0.054515907 0.832182456 0.220668279 0.098781864 POL12 B subunit of DNA polymerase alpha-primase complex YBL036C 0.203816669 0.10506225 -0.458967973 0.030825796 Homolog to twitching motility protein (P. aeroginosa) YBL037W -0.50995488 0.039507578 -0.139849898 0.027220315 APL3 Large subunit of clathrin associated protein complex YBL038W 0.011903164 0.969512114 -0.436315028 0.061699688 MRPL16 Mitochondrial ribosomal protein MRPL16 YBL039C 1.641103523 0.101240934 0.074950286 0.541091171 URA7 CTP synthase, highly homologus to URA8 CTP synthase YBL040C 0.414488628 0.337366554 0.416949682 0.003866974 ERD2 encodes the HDEL receptor required for retention of ER proteins YBL041W 0.302973703 0.334706978 -0.259201017 0.10000259 PRE7 proteasome subunit YBL042C 1.549013444 0.235516871 0.314682648 0.192857668 FUI1 uridine permease YBL043W 0.858385132 0.0428885 -0.778409799 0.03665693 ECM13 (putative) involved in cell wall biogenesis YBL044W -0.19569315 0.623648411 -0.729946359 0.191344608 hypothetical protein YBL045C -0.79287106 0.006255025 0.176388947 0.299817881 COR1 44 kDa core protein of yeast coenzyme QH2 cytochrome c reductase YBL046W 0.3859612 0.081664134 -0.350887344 0.132967365 weak similarity to hypothetical protein YOR054c YBL048W -1.69306352 0.001064383 0.178308538 0.672634552 hypothetical protein YBL049W -1.69519851 0.003376388 -0.008092027 0.984683049 strong similarity to hypothetical protein - human YBL050W -0.41391761 0.141981425 -0.196815486 0.078672316 SEC17 peripheral membrane protein required for vesicular transport between ER and Golgi YBL051C 0.401509441 0.181824349 0.222847746 4.56E-05 hypothetical protein YBL052C 0.26976272 0.09049595 -0.752252813 0.012898381 SAS3 involved in silencing at HMR YBL053W 0.044255282 0.911991193 0.139375926 0.707387167 questionable ORF YBL054W 1.307919818 0.023417029 0.204899594 0.153605143 Homolog to myb transforming proteins YBL055C 0.358491013 0.481932574 -0.250402414 0.070487082 similarity to hypothetical S.pombe protein YBL056W -0.2865873 0.173469012 -0.273953725 0.042656459 PTC3 protein phosphatase type 2C YBL057C -0.32078047 0.406630018 -0.046334252 0.444338998 strong similarity to hypothetical S.pombe protein YBL058W -0.37962486 0.217951768 -0.078208021 0.418770366 SHP1 putative regulatory subunit for Glc7p, a phosphatase required for glucose repression YBL059W 0.462211321 0.198916479 -0.10554177 0.37878554 weak similarity to hypothetical protein YER093c-a YBL060W 0.077003492 0.582507009 -0.474268578 0.026406853 has homology to the sec7 domain of gtp exchange factors YBL061C 0.648278479 0.033692682 0.000146021 0.999335964 SKT5 Probable Ca++ binding membrane protein (prenylated) YBL062W 0.579637219 0.033550656 -0.196912671 0.008308333 questionable ORF YBL063W 0.525577525 0.275713837 0.208608817 0.330500908 KIP1 kinesin related protein YBL064C -1.18003348 0.008713809 -0.0127579 0.959222788 similar to thiol-specific antioxidant enzymes such as rehydrin /peroxiredoxin YBL065W -0.8494896 0.108915753 -0.191671497 0.466324124 questionable ORF YBL066C -0.69422618 0.143848615 0.262468137 0.257366393 SEF1 putative transcription factor YBL067C -0.51185761 0.052322307 -0.525739488 0.149092917 UBP13 ubiquitin carboxyl-terminal hydrolase YBL068W 0.552260638 0.019179853 0.013744302 0.745293033 PRS4 ribose-phosphate pyrophosphokinase 4 YBL069W -0.00725388 0.987732728 -0.025129386 0.8304204 AST1 involved in targeting of plasma membrane [H+]ATPase YBL070C 0.478395103 0.258147059 1.449527927 0.218831982 questionable ORF YBL071C 1.665104942 0.002268259 0.397246315 0.005194289 hypothetical protein YBL072C 2.202569138 0.067628298 0.170422683 0.317507363 RPS8A Ribosomal protein S8A (S14A) (rp19) (YS9) YBL073W -0.40522369 0.129399014 -0.621780705 0.1180431 questionable ORF YBL074C -0.5145695 0.044240228 -0.299340283 0.200705068 AAR2 MATa1-mRNA splicing factor YBL075C -1.40272499 0.038021942 0.103764729 0.516248929 SSA3 heat-inducible cytosolic member of the 70 kDa heat shock protein family YBL076C 0.581969244 0.096179447 0.035319811 0.6166625 ILS1 cytoplasmic isoleucyl-tRNA synthetase YBL077W 1.172703984 0.079621289 0.370471985 0.179126374 questionable ORF YBL078C -0.66417108 0.112692286 0.015724015 0.901271398 AUT7 Aut7p has homology to LC3, a microtubule-associated protein from rat. YBL079W -0.00134744 0.994454663 0.242089261 0.035448994 NUP170 Nucleoporin highly similar to Nup157p and to mammalian Nup155p (nup170 mutant can be complemented with NUP155) YBL080C -0.13981846 0.418501084 -0.465852982 0.073379563 PET112 62-kDa protein YBL081W 1.017113724 0.195899025 0.379908274 0.083287683 hypothetical protein YBL082C 0.289125972 0.451855036 0.462326619 0.194832428 RHK1 putative Dol-P-Man dependent alpha(1-3) mannosyltransferase involved in the biosynthesis of the lipid-linked oligosaccharide YBL083C 0.619332739 0.241584502 0.780879169 0.044070098 questionable ORF YBL085W 0.836764694 0.157704611 0.163004677 0.490774252 BOI1 BEM1-binding protein YBL086C -0.01015504 0.966715371 -0.043958057 0.723896157 involved in sugar metabolism YBL087C 1.69104705 0.026184735 0.387822345 0.047703769 RPL23A Ribosomal protein L23A (L17aA) (YL32) YBL089W 0.155452074 0.725891376 0.094285963 0.732266472 similar to amino acid transport proteins YBL090W 0.130930356 0.447528626 -0.444727802 0.137346139 MRP21 Component of the small subunit of mitochondrial ribosomes YBL091C -0.01592092 0.928530418 0.071111829 0.023003347 MAP2 methionine aminopeptidase 2 YBL092W 1.359675889 0.089999806 0.242349467 0.22278823 RPL32 Ribosomal protein L32 YBL093C 1.630542104 0.066445879 -0.40984133 0.216685648 ROX3 RNA polymerase II holoenzyme /mediator subunit YBL094C 0.152904229 0.515609558 0.109011177 0.180970885 questionable ORF YBL095W -0.59080451 0.004927264 -0.029633732 0.812978335 similarity to C.albicans hypothetical protein YBL096C 0.809338829 0.02935606 0.23293904 0.416154081 questionable ORF YBL097W 0.770433894 0.07368835 -0.361063246 0.146007606 BRN1 involved in chromosome maintenance ; similar to Drosophila barren, Xenopus XCAP-H, and human BRRN1 YBL098W 0.097303301 0.636822178 -0.297569623 0.074939331 similar to kynurenine 3-monoxygenase YBL099W -1.74485012 0.000944171 0.178292671 0.304697955 ATP1 mitochondrial F1F0-ATPase alpha subunit YBL100C -0.95817031 0.163043291 -0.229257504 0.056340994 YBL101C -1.01526877 0.019962145 0.067425577 0.379628367 ECM21 involved in cell wall biogenesis YBL101W-A -0.00154932 0.996505124 0.057147373 0.689363261 TyA gag protein. Gag processing produces capsid proteins. YBL102W -0.08028531 0.556077806 0.31092902 0.159417155 SFT2 similar to mammalian syntaxin 5 YBL103C 0.932300032 0.088718445 -0.176095807 0.262861795 RTG3 Probable cytochrome c subunit, copper binding YBL104C -0.2971584 0.219170985 0.019758268 0.843113947 weak similarity to S.pombe hypothetical protein SPAC12G12.01c YBL105C -0.29337151 0.173608517 0.261086456 0.115317532 PKC1 Protein Kinase C YBL106C -0.47851114 0.139929171 0.226125663 0.146577753 SRO77 yeast homolog of the Drosphila tumor suppressor, lethal giant larvae YBL107C 0.200780264 0.388844229 -0.749110279 0.052248549 hypothetical protein YBL111C -1.05003272 0.021440559 0.440875337 0.111353535 strong similarity to subtelomeric encoded proteins YBL112C 1.191795333 0.432220643 0.287071313 0.006904427 strong similarity to subtelomeric encoded proteins YBR001C -0.86549996 0.021060784 -0.160508473 0.39524395 NTH2 Neutral trehalase, highly homologous to Nth1p YBR002C 0.730283602 0.033873306 -0.289764979 0.119604952 RER2 cis-prenyltransferase YBR003W 0.100169714 0.480672151 -0.063057253 0.495326415 COQ1 hexaprenyl pyrophosphate synthetase YBR004C 1.295560514 0.221698384 0.132653291 0.387742124 similarity to S.pombe hypothetical protein SPAC18B11.05 YBR005W 0.924653953 0.249522237 0.104687752 0.366762602 strong similarity to hypothetical protein YDR003w YBR006W -1.52560357 0.008957363 -0.085669344 0.671433134 UGA2 succinate semialdehyde dehydrogenase YBR007C 0.517934495 0.057829417 -0.066320668 0.644967763 hypothetical protein YBR008C -0.37376243 0.011740901 0.30804565 0.089231413 FLR1 Major Facilitator Transporter YBR009C 1.79607489 0.160621987 -0.128225562 0.64736466 HHF1 Histone H4 (HHF1 and HHF2 code for identical proteins) YBR010W 0.269847874 0.520269233 -0.267808917 0.167146345 HHT1 Histone H3 (HHT1 and HHT2 code for identical proteins) YBR011C 0.711606067 0.094200466 0.487560056 0.077906597 IPP1 Inorganic pyrophosphatase YBR012C 0.020050112 0.961740639 -0.446376426 0.056950447 hypothetical protein YBR012W-A 0.92915986 0.054663881 0.458739681 0.025930922 TyA gag protein. Gag processing produces capsid proteins. The TyB Gag-Pol protein. Gag processing produces capsid proteins. Pol is cleaved to produce protease, reverse transcriptase, and integrase YBR012W-B 0.773827916 0.0389811 0.425029049 0.021804999 activities. YBR013C -0.1495441 0.5715657 -0.891616784 0.176515109 hypothetical protein YBR014C -0.41076534 0.117959158 -0.328502192 0.223802248 Glutaredoxin homolog YBR015C -0.29682379 0.107936446 0.82261182 0.018058492 MNN2 putative Golgi alpha-1,2-mannosyltransferase YBR016W -0.25382865 0.022234531 0.611211515 0.056973834 strong similarity to hypothetical proteins YDL012c and YDR210w YBR017C 0.664689855 0.106855369 0.255720225 0.063517032 KAP104 karyopherin beta 2, yeast transportin YBR018C -1.06276079 0.032440167 0.012997681 0.872951126 GAL7 galactose-1-phosphate uridyl transferase YBR019C -0.12604533 0.238774221 0.347151947 0.127300079 GAL10 UDP-glucose 4-epimerase YBR020W -0.55474059 0.016210963 -0.158015082 0.298445027 GAL1 galactokinase YBR021W 0.954354328 0.01878998 0.205890789 0.238395816 FUR4 uracil permease YBR022W 0.171306102 0.537296624 -0.349686836 0.001841431 hypothetical protein YBR023C 0.912263581 0.103935193 0.098668748 0.380427345 CHS3 chitin synthase 3 YBR024W -0.37180761 0.185577626 -0.224130893 0.118990855 SCO2 SCO1 protein homolog (S. cerevisiae) YBR025C -0.03253562 0.761316582 -0.334788143 0.025259256 probable purine nucleotide-binding protein YBR026C -1.79666811 0.001139509 -0.48834428 0.011001479 MRF1' Nuclear protein that binds to T-rich strand of core consensus sequence of autonomously replicating sequence YBR027C -0.31314044 0.383916149 0.438248599 0.092445593 hypothetical protein YBR028C -0.38795783 0.072758896 -0.181174175 0.043927954 Probable ser /thr-specific protein kinase, homolog to YKR2 and YPK1 (S. cerevisiae) YBR029C 1.873221503 0.202566076 0.439750334 0.025890012 CDS1 CDP-diacylglycerol synthase, CTP-phosphatidic acid cytidylyltransferase, CDP-diglyceride synthetase YBR030W 0.316712433 0.44526422 0.074472979 0.614228624 involved in inositol biosynthesis YBR031W 1.613544394 0.07541802 0.301061615 0.252079647 RPL4A Ribosomal protein L4A (L2A) (rp2) (YL2) YBR032W 1.575502204 0.339951907 0.793243286 0.144359497 hypothetical protein YBR033W -0.6757668 0.124799999 0.098550683 0.308753005 Probable regulatory Zn-finger protein, / homolog to YKL251 / YBR034C 2.228738544 0.203125817 -0.196495292 0.02866966 HMT1 nuclear protein arginine methyltransferase (mono- and asymmetrically dimethylating enzyme) YBR035C 0.130349129 0.80921713 0.13172004 0.328784715 PDX3 pyridoxine (pyridoxiamine) phosphate oxidase YBR036C 0.117417048 0.74068934 0.410956178 0.19827052 CSG2 contains 9 or 10 putative membrane spanning regions ; putative Ca2+ binding protein (homology to EF-hand Ca2+ binding site) YBR037C -0.17067536 0.570646079 0.105247342 0.414885441 SCO1 inner mitochondrial membrane protein YBR038W 0.305385214 0.644042442 0.282925941 0.398128117 CHS2 chitin synthase 2 YBR039W -0.59427459 0.08086054 0.001575296 0.966726017 ATP3 gamma subunit of mitochondrial ATP synthase YBR040W -0.00766125 0.989131704 0.778830158 0.523131592 FIG1 integral membrane protein YBR041W 0.436472937 0.314141745 0.289904233 0.04546478 FAT1 Fatty acid transporter YBR042C 0.242945218 0.666002818 -0.20606029 0.171424177 Probable membrane-bound small GTPase YBR043C 0.953943167 0.427049582 -0.075521683 0.353173974 similarity to benomyl/methotrexate resistance protein YBR044C 0.355155265 0.565508787 0.088443323 0.520230538 TCM62 mitochondrial protein ; (putative) chaperone YBR045C -0.58375387 0.209083688 -0.179532154 0.320474084 GIP1 putative Glc7 regulatory subunit YBR046C -0.50900369 0.078687096 -0.268805608 0.196696574 ZTA1 Homolog to quinone oxidoreductase (E. coli) YBR047W 0.345131914 0.214329255 -0.375710016 0.119849878 hypothetical protein YBR048W 0.603507542 0.135601762 0.102493926 0.627849268 RPS11B Ribosomal protein S11B (S18B) (rp41B) (YS12) YBR050C -2.74260779 0.001202836 -0.011903495 0.793037867 REG2 putative Glc7 regulatory subunit YBR051W -0.79954413 0.198635591 0.200747252 0.555528587 questionable ORF YBR052C -0.8837639 0.008813195 0.174626596 0.274162583 Homolog to YCR004, obr1 (S. pombe), trp repressor binding protein (E. coli) YBR053C -1.26196201 0.007530385 0.064568231 0.696539186 YBR054W -0.82416682 0.202367524 0.058253171 0.867115473 YRO2 Homolog to HSP30 heat shock protein YRO1 (S. cerevisiae) 7 YBR055C 0.065904703 0.47461113 -0.202555733 0.139190571 PRP6 RNA splicing factor YBR056W -1.83846967 0.000290729 -0.210984021 0.039238575 Homolog to glucan-1,3--glucosidase (EC 3.2.1.5 ; S. cerevisiae) 2 YBR057C 0.158454264 0.490280912 -0.566428757 0.108714877 MUM2 similar to ubiquitin C-terminal hydrolase, involved in meiosis YBR058C -0.19594084 0.322758995 -0.164023692 0.137950714 UBP14 Ubiquitin-specific protease YBR058C-A 0.558714653 0.129197159 0.109070903 0.250594504 TSC3 involved in sphingolipid biosynthesis YBR059C -0.34663956 0.363023316 -0.050829423 0.24066309 AKL1 Serine-threonine protein kinase YBR060C 0.27971224 0.531653043 -0.045186231 0.808705202 ORC2 origin recognition complex subunit 2 YBR061C 0.761585229 0.024965194 0.018200302 0.846360181 Homolog to ftsJ protein (E. coli) , / YCR054 / YBR062C 0.288290044 0.014632732 0.143601011 0.300327054 similarity to rat neurodegeneration associated protein 1 YBR063C -0.5003856 0.056147129 -0.656806607 0.011283221 Probable phosphopanthethein-binding protein YBR064W -0.34570159 0.402576203 0.046060395 0.886920932 questionable ORF YBR065C -0.2940729 0.363688044 -0.545170337 0.083682507 ECM2 (putative) involved in cell wall biogenesis and mRNA splicing YBR066C -0.40136934 0.47744334 -0.259366352 0.013534042 NRG2 homologue of NRG1 YBR067C 2.657290624 0.081659989 0.72893684 0.159134158 TIP1 cell wall mannoprotein YBR068C 1.13550092 0.1369263 0.318765583 0.082272981 BAP2 probable amino acid permease for leucine, valine, and isoleucine YBR069C 1.41986915 0.028245424 0.191598764 0.181834414 TAT1 Amino acid transport protein for valine, leucine, isoleucine, and tyrosine YBR070C 0.287654792 0.261069689 0.488579697 0.050932508 involved in osmotolerance YBR071W -0.23404102 0.135316418 0.14837919 0.017435005 hypothetical protein YBR072W -3.85355268 4.35429E-05 0.055242838 0.878228723 HSP26 heat shock protein 26 YBR073W 0.608580829 0.001122145 -0.12753796 0.410414866 RDH54 Putative helicase similar to RAD54 YBR074W -0.19530328 0.290335452 0.128192761 0.57522542 Homolog to aminopeptidase Y (S. cerevisiae) YBR075W -0.25958784 0.091043279 0.413375993 0.045078881 hypothetical protein YBR076W 1.684282025 0.193100244 0.559383528 0.162138918 ECM8 involved in cell wall biogenesis YBR077C 0.234624033 0.520606837 0.083520781 0.08062932 hypothetical protein YBR078W 0.634290106 0.458226343 0.744162625 0.020510107 ECM33 Homolog to sporulation specific protein SPS2 (S. cerevisiae) YBR079C 0.483314438 0.091929106 -0.020022852 0.790565166 RPG1 translation initiation factor eIF3 YBR080C 0.27960895 0.261880228 0.054506911 0.51489527 SEC18 cytoplasmic protein involved in protein transport between ER and Golgi ; ATPase YBR081C 0.015336017 0.901637858 -0.602169656 0.084527129 SPT7 transcription factor, member of the histone acetyltransferase SAGA complex YBR082C 0.745786076 0.215734436 0.458275415 0.052156525 UBC4 ubiquitin-conjugating enzyme YBR083W 0.377419467 0.234500318 0.371096396 0.091487714 TEC1 transcription factor of the TEA /ATTS DNA-binding domain family, regulator of Ty1 expression YBR084C-A 0.770050182 0.112341057 -0.104795619 0.566028018 RPL19A Ribosomal protein L19A (L23A) (rpl5L) (YL14) YBR084W 1.188056859 0.069026391 -0.132718809 0.233223694 MIS1 mitochondrial C1-tetrahydroflate synthase YBR085C-A -0.45963288 0.173741308 -0.115548995 0.121630525 YBR085W 0.775536388 0.315388654 -0.006882046 0.9720062 AAC3 mitochondrial ADP /ATP translocator YBR086C -0.51962399 0.013227985 0.514072473 0.011704358 IST2 Probable transmembrane protein YBR087W 0.366791886 0.080158132 -0.203183639 0.274914747 RFC5 Subunit 5 of Replication Factor C ; homologous to human RFC 38 kDa subunit YBR088C 0.582217388 0.430217799 0.172054271 0.147877261 POL30 Proliferating cell nuclear antigen YBR089C-A 0.353168257 0.001712314 -0.052165544 0.367424144 NHP6B 11-kDa nonhistone chromosomal protein YBR089W 0.502895686 0.47092082 -0.00422055 0.987306874 questionable ORF YBR090C-A 0.234674927 0.291935548 -0.135266362 0.047404854 NHP6B 11-kDa nonhistone chromosomal protein YBR091C 0.504693529 0.216331994 0.315297708 0.017157673 MRS5 Nuclear protein involved in mitochondrial intron splicing YBR092C 1.736442403 0.129025706 0.595934021 0.093824035 PHO3 Acid phosphatase, constitutive YBR093C 0.04984957 0.938038614 0.35220872 0.085780489 PHO5 Acid phosphatase, repressible YBR094W -0.42722508 0.162996742 -0.214104274 0.107077494 weak similarity to pig tubulin-tyrosine ligase YBR095C 0.009708822 0.962635018 -0.725473168 0.050087248 hypothetical protein YBR096W 1.074963895 0.37420027 -0.152282676 0.231555453 hypothetical protein YBR097W -0.114237 0.747320952 -0.03755605 0.341800838 VPS15 Myristoylated Serine /threonine protein kinase involved in vacuolar protein sorting YBR098W -0.01240989 0.97371254 -0.471351921 0.010062509 MMS4 putative transcriptional (co)activator for DNA damage YBR099C 0.168035608 0.814245141 0.466871476 0.069777313 weak similarity to T.brucei mitochondrion hypothetical protein 6 YBR100W 0.008731516 0.990177079 0.31732812 0.40871522 questionable ORF YBR101C 0.248460016 0.413730422 -0.142347219 0.261543905 weak similarity to S.pombe hypothetical protein SPBC3B9.01 YBR102C -0.17083911 0.592619313 -0.456775537 0.075861196 EXO84 Component of the exocyst complex ; homolog in rat brain called rExo84. YBR103W -0.08552846 0.629108182 -0.268252215 0.055159072 SIF2 535 amino acid protein containing 4 WD-40 repeats and a nuclear localization signal YBR104W 1.624948092 0.23686685 -0.305829446 0.036009706 YMC2 mitochondrial carrier protein YBR105C 2.185107187 0.324790108 0.399023242 0.026388571 VID24 peripheral vesicle membrane protein YBR106W 1.150168552 0.218305029 0.182319988 0.000366591 PHO88 regulator of Pho81, involved in regulating phosphate transport YBR107C -0.13651739 0.434793362 0.178345267 0.261216833 IML3 weakly similar to chitin synthases, involved in chromosomal segregation and mitosis YBR108W -0.4074947 0.226531476 0.555071992 0.093589902 Probable transcription factor YBR109C 0.468904245 0.030916527 0.149840856 0.389029838 CMD1 Calmodulin YBR110W 0.087676938 0.770914879 0.0151659 0.799135669 ALG1 beta-1,4-mannosyltransferase YBR111C -0.58976495 0.009540505 -0.238620354 0.037828356 YSA1 Homolog to serendipity protein (D. melanogaster) YBR112C -0.34174347 0.253248329 -0.111182611 0.374115035 CYC8 Transcription regulatory protein YBR113W 0.140320837 0.450798336 -0.054012496 0.72494431 questionable ORF YBR114W -0.29088133 0.191290459 0.001168098 0.9891889 RAD16 Radiation repair protein, putative DNA helicase YBR115C 0.967191336 0.317466492 0.385197467 0.146944543 LYS2 alpha aminoadipate reductase YBR116C -0.80811305 0.257222452 0.335862557 0.445169198 questionable ORF YBR117C -1.2675551 0.086050055 0.467605524 0.057156045 TKL2 transketolase, homologous to tkl1 YBR118W 0.784392039 0.113379642 0.571117676 0.052583248 TEF2 translational elongation factor EF-1 alpha YBR119W -0.30175105 0.270843113 -0.428445728 0.063364151 MUD1 U1 snRNP A protein YBR120C 0.144147453 0.0063578 -0.551668384 0.004814249 CBP6 Translational activator of COB mRNA YBR121C 0.973757136 0.066296132 0.312584642 0.125733917 GRS1 Glycyl-tRNA synthase YBR122C -0.0868928 0.553959129 -0.275073492 0.065433593 MRPL36 Mitochondrial ribosomal protein MRPL36 (YmL36) YBR123C -0.06468012 0.794681223 -0.072130675 0.796488601 TFC1 transcription factor tau (TFIIIC) subunit 95 YBR124W 0.147055961 0.696897079 0.360877443 0.21655836 questionable ORF YBR125C -0.10566963 0.455088005 0.132585626 0.350320599 PTC4 Type 2C protein phosphatase YBR126C -1.59513377 0.000235348 0.253060829 0.285855024 TPS1 56 kD synthase subunit of trehalose-6-phosphate synthase /phosphatase complex YBR127C 0.151899799 0.718318147 0.20003993 0.122565984 VMA2 vacuolar ATPase V1 domain subunit B (60 kDa) YBR128C -1.26969913 0.005563605 -0.054226244 0.560332521 APG14 involved in autophagy YBR129C -0.38589593 0.10676634 -0.624126925 0.046736002 OPY1 involved in mating pathway YBR130C 1.038823318 0.108846277 -0.199476763 0.375345651 SHE3 involved in cell polarity YBR131W 0.485247561 0.036200754 -0.249066232 0.072746414 CCZ1 involved in sporulation, caffeine, calcium, and zinc sensitivity YBR132C -1.20617204 0.008997214 0.500139776 0.143146781 AGP2 Amino acid permease YBR133C -0.00064304 0.996279319 0.369732782 0.150705474 HSL7 regulator of Swe1p kinase YBR134W -0.07990403 0.57447668 0.743239008 0.072579885 questionable ORF YBR135W 0.691560473 0.076914446 0.071993601 0.676545206 CKS1 subunit of the Cdc28 protein kinase YBR137W -0.32311625 0.305348182 -0.425401757 0.014491896 hypothetical protein YBR138C 0.136795656 0.4981847 -0.039309561 0.874119515 HDR1 High-Dosage Reductional segregation defective YBR139W -0.96543825 0.063276494 0.461400818 0.304871161 Probable serine-type carboxypeptidase (EC 3.4.16.1) YBR141C 0.591206019 0.08365463 0.034631733 0.781829905 hypothetical protein YBR142W 0.924343108 0.07339726 -0.580227207 0.057499394 MAK5 Probable pre-mRNA splicing RNA-helicase YBR143C 0.90735503 0.133972393 -0.319131944 0.046765953 SUP45 Homolog of eRF1 (eukaryotic Release Factor 1) in other metazoans. YBR144C 0.787480735 0.017024633 0.111093197 0.707300023 hypothetical protein YBR145W 1.69860482 0.199756232 0.314429383 0.17851089 ADH5 alcohol dehydrogenase isoenzyme V YBR146W 0.852689267 0.044002513 -0.427577062 0.005947323 MRPS9 Probable mitochondrial ribosomal protein S9 YBR147W 0.086878594 0.894271649 0.01857904 0.909256222 strong similarity to hypothetical protein YOL092w YBR148W 0.057009993 0.9378736 -0.505071738 0.016737578 YSW1 Spore-specific protein YBR149W -0.14603105 0.560710049 0.322233096 0.118067079 ARA1 D-arabinose dehydrogenase YBR150C -0.06849098 0.61877767 0.277404305 0.084780353 TBS1 Probable Zn-finger protein YBR151W 0.140882013 0.673956787 0.048499399 0.637535428 APD1 Actin Patches Distal YBR152W -0.31696976 0.186103218 -0.014294108 0.805824901 SPP381 U4 /U6.U5-associated snRNP protein ; contains a PEST proteolysis motif YBR153W 0.880774474 0.037629888 -0.137620267 0.430846051 RIB7 Riboflavin biosynthesis protein YBR154C 0.979098423 0.114884829 -0.678603044 0.069627695 RPB5 25-kDa RNA polymerase subunit (common to polymerases I, II and III) YBR155W 0.926643818 0.015741964 -0.423299063 0.192250705 CNS1 component of Hsp90p chaperone machinery YBR156C 0.621018615 0.041226544 -0.030346914 0.793541769 SLI15 Mitotic spindle protein involved in chromosome segregation. YBR157C -1.71986712 0.006172362 -0.248741575 0.085629762 ICS2 Increased Copper Sensitivity YBR158W 0.236090001 0.758909223 0.003422235 0.975268559 CST13 Chromosome STability protein YBR159W -0.40798658 0.146111319 -0.208230612 0.088504671 similarity to human 17-beta-hydroxysteroid dehydrogenase YBR160W 1.382688997 0.033637934 -0.089047975 0.31179147 CDC28 protein kinase catalytic subunit YBR161W -0.08785666 0.596919377 0.10257468 0.214915307 Homolog to suppressor of reduced viability of starvation (SUR1, S. cerevisiae) YBR162C 2.767805354 0.381081775 1.025781406 0.062845102 TOS1 similarity to hypothetical protein YJL171c YBR162W-A 1.090844591 0.12050417 -0.031166834 0.876106659 YSY6 involved in the secretory pathway YBR163W 0.083305197 0.771358216 -0.075321539 0.202356609 DEM1 Weak similarity to Pta1p (pre-tRNA processing protein) YBR164C 0.386971951 0.146788473 -0.30730063 0.279077924 ARL1 ADP-ribosylation factor-like protein 1 YBR165W 0.478450374 0.031594004 -0.110574637 0.068503035 UBS1 positive regulator of CDC34, involved in ubiquitin-mediated degradation YBR166C 1.077223888 0.119812637 -0.348329997 0.052540766 TYR1 Prephenate dehydrogenase (NADP+) YBR167C 0.725530505 0.085284247 -0.575616057 0.091172258 POP7 Pop7 protein, an integral subunit of RNase P and apparent subunit of RNase MRP YBR168W -0.33172247 0.013489087 -0.238383677 0.214573005 weak similarity to hypothetical protein YLR324w YBR169C -2.00430362 0.001309944 -0.237279361 0.207385649 SSE2 HSP70 family member, highly homologous to Sse1p YBR170C -0.38862164 0.009161953 -0.121312664 0.233974664 NPL4 Suppressor of SEC63 (S.cerevisiae), novel ER translocation component glycoprotein complexed with Sec62p and Sec63p in the Sec63 complex, an integral endoplasmic reticulum membrane protein complex YBR171W 0.465550263 0.391762515 -0.176381153 0.13428994 SEC66 required for translocation of presecretory proteins YBR172C 0.947045973 0.058028345 -0.240825609 0.324855802 SMY2 Kinesin-related protein suppressing myosin defects (MYO2) YBR173C 0.543487569 0.028689108 0.89073289 0.059037897 UMP1 20S proteasome maturation factor YBR174C -0.09574649 0.828021009 0.26542884 0.343600031 weak similarity to hypothetical protein YLR324w YBR175W 0.798115784 0.356656435 -0.050382926 0.123809345 Probable GTP-binding protein YBR176W 0.068803244 0.470897562 -0.394319913 0.027244144 ECM31 Alpha-Ketoisovalerate Hydroxymethyltransferase YBR177C -0.40821177 0.268763947 0.220857848 0.117486244 EHT1 alcohol acyl transferase YBR178W 0.171444756 0.6310156 0.259352923 0.551351751 questionable ORF homolog of Drosophila melanogaster fuzzy onions gene ; integral protein of the mitochondrial outer membrane which can be isolated as part of YBR179C 0.242929175 0.48422383 -0.167702237 0.424783503 FZO1 a high molecular weight complex YBR180W 0.497811941 0.321911208 -0.383876643 0.054128279 DTR1 dityrosine transporter MFS-MDR YBR181C 1.517480365 0.18681994 -0.277696415 0.046526669 RPS6B 40S ribosomal gene product S6B (S10B) (rp9) (YS4) YBR182C 1.07336623 0.32780709 0.107229696 0.503375908 SMP1 Probable DNA-binding transcription factor, Homolog to SRF /SL-2 YBR183W -0.32932225 0.100358245 0.024285921 0.81373346 YPC1 alkaline ceramidase with reverse activity YBR184W 0.532165774 0.05305851 -0.540524633 0.016569575 MEL1 alpha-galactosidase YBR185C -0.21994541 0.229580372 -0.395388433 0.0119799 MBA1 involved in assembly of mitochondrial respiratory complexes YBR186W 0.490784688 0.38844514 0.192577179 0.445672946 PCH2 Putative ATPase YBR187W 0.690417855 0.049928975 -0.257469763 0.087483562 probable membrane protein YBR188C 0.492925293 0.053081384 -0.025801954 0.86150773 NTC20 splicing factor YBR189W 0.950615102 0.051056367 0.047228918 0.81597576 RPS9B Ribosomal protein S9B (S13) (rp21) (YS11) YBR190W 0.854062672 0.084939876 0.106675398 0.396889145 questionable ORF YBR191W 0.575714408 0.535778578 0.080457252 0.439970647 RPL21A Ribosomal protein L21A YBR192W 0.509881138 0.005373514 -0.202658011 0.151330428 RIM2 Probable carrier protein, mitochondrial YBR193C -0.34403382 0.012995649 0.03899841 0.70048146 MED8 Stoichiometric member of mediator complex YBR194W 0.822733309 0.027278178 -0.138921462 0.204751803 hypothetical protein p50 subunit of the yeast omatin Assembly Factor-I (CAF-I) negative regulator of ras-mediated cAMP induction ; homologous to beta subunit of YBR195C 0.225699086 0.306618626 0.036364069 0.407332903 MSI1 GTP-binding proteins YBR196C 1.367685111 0.219334764 0.633114599 0.120857313 PGI1 Glucose-6-phosphate isomerase YBR197C -0.38684265 0.205152386 0.138519858 0.310187653 YBR198C -0.5545939 0.044090014 -0.139263158 0.110161572 TAF90 Probable transcription-associated factor protein, probable -transducin type YBR200W -0.15441417 0.540836335 -0.262692526 0.109752107 BEM1 contains two SH3 domains YBR201W 0.056424906 0.888422959 -0.235405671 0.187107537 DER1 involved in degradation in the ER YBR203W -0.33775006 0.576361511 -0.2045828 0.089979675 hypothetical protein YBR204C -0.90498283 0.00040729 -0.360269663 0.102683009 Probable serine-active lipase, peroxisomal (EX 3.1.1.-) YBR205W -0.27879779 0.043595084 0.018995774 0.840490764 KTR3 Putative alpha-1,2-mannosyltransferase YBR206W 0.318754718 0.295731593 0.345147806 0.229701265 questionable ORF YBR207W 0.242939647 0.453039051 0.107702995 0.194904608 FTH1 probable membrane protein YBR208C -0.88846186 0.148064307 0.245161263 0.391157674 DUR1,2 Urea amidolyase (contains urea carboxylase and allophanate hydrolase) YBR209W 2.248661321 0.297551441 0.381258931 0.281716371 hypothetical protein YBR210W 0.940789823 0.054030573 0.313341233 0.206973905 strong similarity to D.melanogaster cornichon protein YBR211C -0.31232008 0.154179443 -0.349551777 0.068109672 AME1 regulator of microtubule stability YBR212W -0.16875438 0.27183768 0.70435044 0.055337423 NGR1 negative growth regulatory protein YBR213W 0.273519351 0.582528693 0.202209774 0.245502392 MET8 Effector in the expression of PAPS reductase and sulfite reductase YBR214W -0.57347024 0.126908367 -0.125397825 0.063363362 SDS24 nuclear protein similar to pombe sds23 YBR215W 0.017037639 0.945053353 -0.372937798 0.19145978 HPC2 highly charged, basic protein YBR216C -0.00884559 0.953941411 -0.167736664 0.234462904 strong similarity to hypothetical protein YGL060w YBR217W -0.29756814 0.097019236 -0.832730836 0.036759735 APG12 involved in autophagy YBR218C -1.09366079 0.009460379 0.31101953 0.03629335 PYC2 pyruvate carboxylase YBR219C 0.335357966 0.235666601 0.453103199 0.146167607 YBR220C -0.14753261 0.152773414 0.043535552 0.58680398 similarity to human acetyl-coenzyme A transporter YBR221C 0.665723843 0.023979323 0.345653586 0.090351575 PDB1 beta subunit of pyruvate dehydrogenase (E1 beta) YBR222C 0.177197636 0.328760318 0.523832581 0.115135526 FAT2 Probable AMP-binding protein YBR223C -0.36083419 0.162988917 0.236622488 0.091031072 hypothetical protein YBR224W 0.533319791 0.523528918 -0.105555358 0.450829681 questionable ORF YBR225W -0.45521538 0.133909158 0.149731073 0.12255293 hypothetical protein YBR226C -0.1493116 0.540340059 0.398830403 0.134948712 questionable ORF YBR227C -0.02690793 0.804430878 -0.542974523 0.06158401 MCX1 Mitochondrial ATP-binding protein, similar to ClpX YBR228W -0.15251099 0.540466654 -0.30761674 0.088148112 similarity to hypothetical A.thaliana protein YBR229C -0.65280659 0.004625347 0.346345079 0.066488919 ROT2 Glucosidase II YBR230C -1.32094486 0.005924621 0.609470924 0.098929907 hypothetical protein YBR231C -0.19457994 0.205157819 -0.12528603 0.492388082 AOR1 Actin Overexpression Resistant YBR232C -0.25897947 0.337666247 -0.256882124 0.220949911 questionable ORF YBR233W 0.298632757 0.196470769 -0.167429571 0.303627903 PBP2 Homolog to human hnRNP complex K protein YBR234C -0.15061112 0.59134678 0.327554697 0.154113499 ARC40 component of Arp2 /Arp3 protein complex YBR235W -0.51010999 0.136185575 0.324796317 0.268142217 similarity to bumetanide-sensitive Na-K-Cl cotransport protein YBR236C -0.19651971 0.061628045 -0.424220761 0.074955691 ABD1 RNA (guanine-7-)methyltransferase (cap methyltransferase) YBR237W -0.04008757 0.626709146 -0.669193526 0.026466683 PRP5 RNA helicase homolog YBR238C 1.051169484 0.099958654 0.041128377 0.699872898 strong similarity to general chromatin factor Spt16p YBR239C -0.07996564 0.770885499 0.202238628 0.315917042 Probable Zn-finger protein YBR240C 0.721961605 0.06041823 0.08649645 0.403227564 THI2 Probable Zn-finger protein YBR241C -0.76927116 0.145479129 1.14753597 0.115479885 Probable sugar transport protein YBR242W 0.224206378 0.436104651 -0.246551427 0.166744907 Probable ATP /GTP-binding protein YBR243C 0.126453815 0.601538183 0.511759088 0.087117753 ALG7 UDP-N-acetyl-glucosamine-1-P transferase (GPT) YBR244W -0.04024886 0.876819875 -0.116780138 0.370779064 GPX2 Probable glutathione peroxidase (EC 1.11.1.9) YBR245C -0.13301951 0.656090366 -0.071741569 0.452528359 ISW1 ATPase component of a four subunit chromatin remodeling complex YBR246W 0.388094181 0.115107815 0.389870478 0.015081075 hypothetical protein YBR247C 0.806603288 0.088880609 -0.254803962 0.212989418 ENP1 Putative 57 kDa protein with an apparent MW of 70 kDa by SDS-PAGE YBR248C 0.653441412 0.163592168 -0.191623286 0.181164198 HIS7 glutamine amidotransferase:cyclase, also called imidazole glycerol phosphate synthase YBR249C 1.348261644 0.153199225 0.032589822 0.736940757 ARO4 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase isoenzyme YBR250W 0.224285641 0.140766893 0.073786024 0.397492969 hypothetical protein YBR251W -0.11786867 0.494992133 -0.507917338 0.045434132 MRPS5 Probable mitochondrial ribosomal protein S5 YBR252W 1.903287036 0.147563507 0.458420776 0.017844943 DUT1 dUTP pyrophosphatase (dUTPase) YBR253W -0.14706684 0.324101008 -0.219063569 0.388466951 SRB6 transcription factor, part of Srb /Mediator complex YBR254C 0.639546525 0.287172459 -0.24298537 0.173539408 TRS20 TRAPP subunit of 20 kDa involved in targeting and fusion of ER to golgi transport vesicles YBR255W -0.41858626 0.152901982 -0.202385797 0.056861948 hypothetical protein YBR256C 0.930878649 0.187486647 -0.755503374 0.004847495 RIB5 Riboflavin synthase alpha-chain YBR257W 0.494753717 0.121237704 -0.462654215 0.111724708 POP4 protein component of RNase MRP and RNaseP YBR258C 0.725078695 0.030760877 -0.380549217 0.163616798 hypothetical protein YBR259W -0.24135173 0.069161552 -0.575328244 0.013191416 hypothetical protein YBR261C 0.539891551 0.272526166 0.185642064 0.109354215 similarity to hypothetical S. pombe protein YBR262C 1.000878929 0.014189283 0.034411521 0.72352909 questionable ORF YBR263W 0.150391027 0.622692791 0.271419058 0.293089621 SHM1 Serine hydroxymethyltransferase, mitochondrial YBR264C 0.007710954 0.984647757 -0.012657818 0.933117184 YPT10 similar to Rab proteins and other small GTP-binding proteins YBR265W 0.113829029 0.660366462 0.302990222 0.414465599 TSC10 3-ketosphinganine reductase YBR266C 1.120137295 0.004583262 -0.302187127 0.115279102 probable membrane protein YBR267W 1.63309769 0.012759847 -0.218004739 0.194116482 Probable Zn-finger protein (C2H2 type) YBR268W 0.962401766 0.003472891 0.027069757 0.816614251 MRPL37 Probable mitochondrial protein L37 YBR269C 0.014617611 0.909089789 0.406037746 0.069260539 hypothetical protein YBR270C -0.72538404 0.019767546 0.832718798 0.187401744 Probable ATP /GTP-binding protein YBR271W 0.173871886 0.205547877 -0.200456239 0.480922068 weak similarity to S.pombe uvi22 protein and hypothetical protein YNL024c YBR272C -0.49903178 0.039523648 -0.40658334 0.062265263 HSM3 mismatch repair protein /Hsm3p may be a member of the yeast MutS homolog family YBR273C -0.22105569 0.42890499 -0.1992883 0.20643045 YBR274W -0.40407486 0.114561032 -0.08893171 0.240788722 CHK1 Protein kinase Chk1 YBR275C 0.035634114 0.696102795 -0.04309139 0.807197749 RIF1 RAP1-interacting factor, involved in establishment of repressed chromatin YBR276C -0.33622662 0.135679939 -0.283470679 0.058195793 PPS1 dual specificity protein phosphatase YBR277C -0.26031884 0.290686091 -0.49239054 0.103704148 questionable ORF YBR278W -0.69552819 0.005303882 -0.447940644 0.074334828 DPB3 C and C' subunits of DNA polymerase II YBR279W 0.38369094 0.085309425 -0.485132906 0.233939856 PAF1 RNA polymerase II-associated protein YBR280C -0.9340368 0.043841773 0.035173859 0.667366308 hypothetical protein YBR281C 0.650829088 0.006817527 -0.022736831 0.750042188 Probable G-protein, -transducin type YBR282W 0.71505966 0.030645507 -0.464903536 0.080006278 MRPL27 Mitochondrial ribosomal protein MRPL27 (YmL27) YBR283C 0.892968455 0.073360951 0.823994118 0.017031024 SSH1 Probable SEC61 protein homolog YBR284W 0.019696592 0.963814119 0.045369302 0.551470936 similarity to AMP deaminase YBR285W -2.66001153 6.84735E-05 0.074298437 0.739763547 hypothetical protein YBR286W 0.251657324 0.243028097 0.566023743 0.182158267 APE3 Aminopeptidase yscIII YBR287W -0.18629357 0.74271645 0.355482309 0.235650164 similarity to hypothetical S. pombe protein YBR288C 0.750492999 0.217497619 -0.43257038 0.011643298 APM3 clathrin associated protein medium chain YBR289W -0.09826974 0.227247394 -0.233803768 0.049502185 SNF5 subunit of the chromatin remodeling Snf /Swi complex YBR290W 0.123035172 0.70556047 -1.127418439 0.046042061 BSD2 copper transporter YBR291C 2.181933332 0.241168804 -0.01129882 0.793295319 CTP1 citrate tranporter in mitochondrial inner membrane YBR292C 1.038407015 0.009510833 0.549401791 0.026657493 hypothetical protein YBR293W 0.386585146 0.050566207 -0.194228969 0.196222353 Probable multidrug resistance protein YBR294W -0.28798904 0.536211905 0.162073537 0.148736468 SUL1 Probable sulfate transport protein YBR295W 0.043871521 0.890476153 0.203627048 0.495255943 PCA1 Putative P-type Cu(2+)-transporting ATPase YBR296C -1.31625401 0.187575662 0.351496454 0.340942012 PHO89 Probable Na+ /Pi symporter YBR297W 0.428669808 0.329587918 0.249924475 0.022039665 MAL33 MAL-activator protein YBR298C -1.1710578 0.000745128 0.149218054 0.223507479 MAL31 Maltose permease YBR299W -0.81784101 0.016099907 0.027859457 0.875036619 MAL32 Maltase YBR300C -0.07515303 0.792152865 0.094764948 0.703543927 strong similarity to hypothetical protein YGR293c YBR301W -0.02853428 0.869233629 0.556361717 0.182610168 strong similarity to members of the Srp1p/Tip1p family YBR302C 0.071979462 0.870739718 -0.041588696 0.834063255 COS2 similar to other members of the Cos family, coded from subtelomeric region YCL002C 0.233291813 0.156894345 0.344533981 0.157793204 strong similarity to Saccharomyces pastorianus hypothetical protein LgYCL002c YCL004W -0.13653197 0.620223287 -0.028131853 0.666835756 PGS1 17 kDa phosphatidylglycerolphosphate synthase YCL005W 0.461090315 0.005712551 0.48275224 0.03849604 strong similarity to Saccharomyces pastorianus hypothetical protein LgYCL005w YCL007C 0.701381923 0.101478718 -0.226348843 0.070920354 CWH36 involved in cell wall biogenesis YCL008C 0.427867786 0.526864047 0.43339347 0.330065286 STP22 homologous to mouse and human Tsg101 tumor susceptibility genes YCL009C 0.40693392 0.502156255 0.342661335 0.026809035 ILV6 Small regulatory subunit of Acetolactate synthase YCL010C -0.25944003 0.542622163 -0.141020782 0.341088617 strong similarity to Saccharomyces pastorianus hypothetical protein LgYCL010c YCL011C -0.19722557 0.367221833 -0.11119195 0.240098603 GBP2 Protein with RNA recognition motifs YCL012W -0.53232875 0.136650404 0.36029898 0.046606299 part of budding protein Bud3p due to frameshift in DNA sequence YCL014W -0.00251603 0.994411539 -0.092927205 0.240243771 BUD3 Cell cycle regulated protein required for axial bud formation ; co-assembles with Bud4p at bud sites//budding protein YCL016C -0.37237138 0.076755229 0.173709625 0.401282592 DCC1 part of an alternative RFC complex YCL017C -0.24772129 0.191560122 -0.108234278 0.411776702 NFS1 regulates Iron-Sulfur cluster proteins, cellular Iron uptake, andIron distribution/NifS-like protein YCL018W -0.38889057 0.063534112 -0.121694107 0.301365363 LEU2 beta-IPM (isopropylmalate) dehydrogenase YCL019W 0.103855538 0.837669267 0.05087852 0.759636108 POL polyprotein YCL020W -0.09272221 0.651705871 -0.081297813 0.348182926 GAG polyprotein YCL022C -0.08161966 0.757833619 0.418620694 0.226747228 questionable ORF YCL023C 0.253790421 0.167299553 0.057655581 0.693748043 questionable ORF YCL024W -0.03007074 0.875206698 0.262926667 0.411772502 KCC4 protein kinase related to S. pombe Nim1p YCL025C -0.03632079 0.961295667 -0.229308228 0.624638235 AGP1 Amino acid permease YCL028W -0.13823754 0.363795652 0.197423864 0.020100272 RNQ1 transferable epigenetic modifier YCL029C 0.318326618 0.216060985 -0.16871408 0.4775348 BIK1 Microtubule-binding protein YCL030C -0.39340505 0.15107762 0.00164512 0.98196901 HIS4 histidinol dehydrogenase YCL031C 1.111253494 0.054141835 -0.732044438 0.092436232 RRP7 involved in rRNA processing YCL032W -0.04067269 0.829594532 0.029963522 0.769765063 STE50 possesses a SAM (sterile alpha motif) ; interacts with G protein and Ste11p//pheromone response pathway protein YCL033C -0.57877739 0.01617187 0.355918796 0.275674357 Transcription regulator YCL034W -0.7882154 0.009147107 0.163242568 0.343240181 similarity to hypothetical S.pombe protein YCL035C -0.27652739 0.575274358 0.051237264 0.72682063 GRX1 Glutaredoxin YCL036W -0.42872205 0.248571554 0.078957981 0.324033565 similarity to hypothetical protein YDR514c YCL037C 0.779786056 0.040403754 0.870911652 0.021547099 SRO9 RNA binding protein with La motif YCL038C -1.06235976 0.04592205 0.33559446 0.353270236 Membrane transporter YCL039W -0.91461348 0.016720432 0.385747537 0.014334748 regulatory protein YCL040W -1.09899477 0.000430123 0.136285383 0.630780745 GLK1 Glucokinase YCL042W -0.90472203 0.092506085 0.511993027 0.183101984 questionable ORF YCL043C -0.13561567 0.274279895 0.564921772 0.169640252 PDI1 protein disulfide isomerase YCL044C -0.12153399 0.798492919 0.324842289 0.184231221 hypothetical protein YCL045C 0.173704409 0.200526478 0.435608878 0.110175692 weak similarity to human ORF YCL046W -0.07510615 0.789396175 0.566988608 0.078848018 questionable ORF YCL047C -0.3436443 0.063047287 -0.350082851 0.027216203 hypothetical protein YCL048W -0.293194 0.118608193 -0.171432712 0.309459232 strong similarity to sporulation-specific protein Sps2p YCL049C -0.22736916 0.581455376 0.020090451 0.92124291 hypothetical protein YCL050C 1.200711575 0.177532507 0.372834751 0.029229123 APA1 diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase I YCL051W -0.05622379 0.543067464 -0.109475829 0.219411515 LRE1 involved in laminarase resistance YCL052C -0.25745447 0.289108271 -0.077160051 0.371869631 PBN1 Protease B, nonderepressible form YCL054W 1.504395251 0.061598507 -0.774518773 0.052048578 SPB1 Putative methyltransferase YCL055W 0.311924176 0.510663765 -0.239812236 0.116107645 KAR4 transcription factor involved in karyogamy YCL056C 0.188672916 0.209921488 -0.250851317 0.169595348 hypothetical protein YCL057W -0.45213136 0.107207335 0.257159891 0.346861644 PRD1 Saccharolysin (oligopeptidase yscD) YCL058C 0.442706384 0.131742991 0.274005591 0.090164441 hypothetical protein YCL059C 0.528020464 0.008328001 -1.237610027 0.020166823 KRR1 involved in cell division and spore germination YCL061C -0.68262457 0.16764337 -0.753950305 0.023443596 MRC1 similarity to URK1 YCL063W 0.645438708 0.2300253 0.655050216 0.173555279 weak similarity to yeast translation regulator Gcd6p YCL064C 0.406197902 0.3093267 -0.438401288 0.14835045 CHA1 catabolic serine (threonine) dehydratase YCL065W 0.708566031 0.174876713 0.689610607 0.064783199 hypotetical protein YCL066W -0.02091115 0.966127771 0.676956446 0.191334011 HMLALPHAtranscription factor involved in the regulation of alpha-specific genes YCL067C -0.33754707 0.193582361 -0.924582742 0.053504917 HMLALPHAMating type protein alpha-2 YCL068C -0.76551595 0.00313142 0.274495019 0.318174445 Bud site selection YCL069W -0.75048818 0.063417731 -0.295665528 0.16175713 strong similarity to drug resistance protein SGE1 YCL073C -0.60325134 0.033602912 -0.052911804 0.868177814 strong similarity to subtelomeric encoded proteins YCL074W -0.0852562 0.811691383 1.12931772 0.348460437 Psuedogene: encodes fragment of Ty Pol protein /Reverse transcriptase YCL075W 1.46202347 0.487165713 0.08819935 0.681675808 Homologous to a portion of the Aspartic protease signature Copia /TY1 family transposons. YCL076W 0.64036824 0.57239636 0.089049526 0.303716763 Hypothetical ORF YCR001W -0.3313965 0.210258611 -0.457339037 0.081897193 weak similarity to chloride channel proteins YCR002C 0.930211987 0.191963991 -0.126857473 0.07795437 CDC10 conserved potential GTP-ginding protein YCR003W 0.66865384 0.209152325 -0.473828324 0.016039911 MRPL32 Mitochondrial ribosomal protein MRPL32 (YmL32) YCR004C -0.13772514 0.610062347 0.139599795 0.224666739 YCP4 FMN-binding protein YCR005C 1.776528791 0.354902569 0.183943024 0.459115728 CIT2 non-mitochondrial citrate synthase YCR006C 0.542087517 0.026848639 0.152312598 0.260846156 YCR007C 0.420906915 0.565117946 -0.450712013 0.113672069 YCR008W -0.08060751 0.699158057 0.424926519 0.032871485 SAT4 Ser /Thr protein kinase YCR009C -0.1576904 0.627393721 -0.356895363 0.063043436 RVS161 Reduced viability on starvation protein RVS161 YCR010C -0.37401683 0.50646338 0.533083263 0.046227535 SPG2 YCR012W 0.852054817 0.470592487 0.485390872 0.169738623 PGK1 3-phosphoglycerate kinase YCR013C 1.350276059 0.325305903 0.508463498 0.209038001 YCR014C -0.77165546 0.012240252 -0.293423305 0.178980165 POL4 DNA polymerase IV YCR015C 0.48659745 0.132075289 -0.419248327 0.214641669 YCR016W 1.006874197 0.202729787 -0.923279026 0.04279018 YCR017C -0.10110951 0.555578847 0.458468047 0.098755146 YCR019W -0.36423501 0.108346278 0.122014611 0.139665519 MAK32 MAK32 sugar kinase YCR020C 3.077502622 0.237442646 0.298837156 0.052664577 PET18 Transcription regulator YCR020C-A 0.492002206 0.155352846 0.326280024 0.188951564 MAK31 MAK31 snRNP YCR020W-B -0.04011701 0.817708447 -0.863556984 0.039449987 HTL1 high-temperature lethal YCR021C -3.1082561 4.92928E-05 0.144669705 0.583608489 HSP30 Protein induced by heat shock, ethanol treatment, and entry into stationary phase ; located in plasma membrane YCR022C 1.233984543 0.023754963 0.414354646 0.149099618 hypothetical protein YCR023C -0.74423643 0.019299375 -0.07230973 0.233072767 Membrane transporter YCR024C 0.447688975 0.102292302 0.078933764 0.009344502 Asn-tRNA synthetase YCR025C 0.10125868 0.685133914 0.478780262 0.318801347 hypothetical protein YCR027C 0.296522896 0.131750957 -0.291018028 0.066757938 RSG1 rheb-like Gene involved in growth regulation/GTP-binding protein, ras family YCR028C -0.02599689 0.918110804 -0.099231143 0.119900367 FEN2 Amino acid permease YCR028C-A 0.213248895 0.644053146 0.343367676 0.005161637 RIM1 Single-stranded zinc finger DNA-binding protein YCR030C -0.94376038 0.029642486 0.509101594 0.012033517 YCR033W 0.174662719 0.2073373 0.147838891 0.18799601 similarity to nuclear receptor co-repressor N-Cor YCR034W 1.744009443 0.244683841 0.648708104 0.030562849 FEN1 Probable subunit of 1,3-beta-glucan synthase ; homolog of ELO1 YCR035C 0.494679342 0.016675749 -0.502418016 0.019026857 RRP43 Component of the exosome 3->5 exoribonuclease complex with Rrp4p, Rrp41p, Rrp42p and Dis3p (Rrp44p). YCR036W -0.09699581 0.649902206 -0.164009429 0.110375676 RBK1 ribokinase YCR037C 0.72709016 0.047120443 0.103587555 0.308690359 PHO87 phosphate permease YCR038C -0.42881356 0.189090967 0.280656296 0.117446151 BUD5 GTP /GDP exchange factor for Rsr1 protein YCR039C -0.23985913 0.018668122 -0.856749087 0.056321313 MATALPHA Mating type protein alpha-2 YCR040W 0.626259016 0.109702101 -0.070031617 0.81789174 MATALPHA transcription factor involved in the regulation of alpha-specific genes YCR041W 0.582362057 0.140822515 0.508767954 0.100165639 questionable ORF YCR042C 0.01135124 0.954434545 0.524735777 0.02708746 TSM1 TATA binding protein-associated factor (TAF) YCR043C 1.260961237 0.20575485 0.08769803 0.233125092 hypothetical protein YCR044C 0.217803182 0.265515222 0.430766664 0.169778001 PER1 Protein Processing in the ER YCR046C 0.823583115 0.172343225 0.130757379 0.025919264 IMG1 mitochondrial ribosomal protein YCR047C 0.29163712 0.370007416 0.318764826 0.031013533 Protein carboxyl methylase YCR048W 0.2736226 0.135605408 0.186640495 0.387662825 ARE1 Acyl-CoA cholesterol acyltransferase (sterol-ester synthetase) YCR049C 0.452885473 0.258362692 0.486339687 0.057395929 questionable ORF YCR050C 0.332825636 0.359414438 0.365424844 0.169781668 questionable ORF YCR051W 0.729831146 0.054996047 0.066904471 0.213159132 weak similarity to ankyrins YCR052W 0.114326729 0.272102128 0.171944294 0.121399176 RSC6 subunit of chromatin remodeling complex CTR86 shares a terminator region with THR4. CTR86 contains aGCN4 responsive site suggesting it may also be involved in amino acid YCR054C 0.383871933 0.147082978 -0.230720553 0.255024422 CTR86 biosynthesis. YCR057C 0.614686667 0.098949828 -0.182083188 0.2295728 PWP2 regulatory protein YCR059C 1.210109557 0.113528924 0.317163538 0.022490846 PMN1 piecemeal microautophagy of the nucleus (PMN) YCR060W 1.198922074 0.010400307 0.453599977 0.046926503 regulatory protein YCR061W -0.82105488 0.117511854 1.116690939 0.017054438 similarity to YTP1 YCR063W -0.29770553 0.606713447 0.418311719 0.264234762 similarity to Ytp1p protein YCR064C 1.039972722 0.065212513 0.913456205 0.029520564 G10-like protein YCR065W 0.673880225 0.054667552 0.405328291 0.007542787 YCR066W 0.025516194 0.962703441 0.516519352 0.320265801 HCM1 Transcription factor (fork head domain) YCR067C 0.142378538 0.123206814 0.336715903 0.267378725 SED4 Intracellular transport protein YCR068W -0.80397063 0.11462737 0.37869312 0.177922051 CVT17 Putative lipase required for the breakdown of Cvt bodies and autophagic bodies YCR069W -0.86602745 0.025209687 0.261420162 0.209173833 SCC3 cyclophilin homolog YCR071C 0.556108762 0.068767776 -0.055227192 0.658277811 IMG2 similar to Drosophila gonadal protein Z600 ; involved in mitochondrial DNA maitenance YCR072C 1.002167013 0.054659606 0.141691365 0.016054417 regulatory protein YCR073C 0.758618783 0.044606551 0.400324147 0.121081632 SSK22 protein kinase YCR073W-A -1.40461228 0.002558076 0.144508113 0.017198388 SOL2 shows similarity to glucose-6-phosphate dehydrogenase non-catalytic domains ; homologous to Sol1p and Sol3p YCR075C -1.25273988 0.00124749 0.491906314 0.042820992 ERS1 ERS1 protein, ER defect supressor YCR076C -0.71070684 0.015086607 0.488428686 0.198802405 hypothetical protein YCR079W -0.70112461 0.004146691 0.217787921 0.06231288 weak similarity to A.thaliana protein phosphatase 2C YCR081W 0.453559115 0.024412369 -0.148265434 0.169783944 SRB8 RNA polymerase II mediator subunit YCR082W -1.00504096 0.023438456 0.088433033 0.550230499 weak similarity to Rbk1p YCR083W -0.71152747 0.036551603 -0.291894008 0.01313871 TRX3 mitochondrial thioredoxin YCR084C 0.175901265 0.723133174 0.371075446 0.209697284 TUP1 glucose repression regulatory protein, exhibits similarity to beta subunits of G proteins YCR085W 0.862744523 0.082992925 0.019296688 0.950372471 hypothetical protein YCR086W 0.319115765 0.005084262 0.185000118 0.285505869 involved in nuclear migration YCR087C-A 1.077630492 0.030298282 -0.162116909 0.424261789 nucleic acid-binding protein YCR087W 1.010533486 0.118125123 0.305564029 0.213396059 questionable ORF YCR088W -0.89560588 0.047273951 0.187194347 0.586488573 ABP1 Actin binding protein YCR090C 1.004158898 0.025376236 -0.210386114 0.276899692 similarity to S. pombe SPBC2D10.03c Putative serine /threonine protein kinase most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C YCR091W -1.22700723 0.005061876 0.205238193 0.338362658 KIN82 subfamily mutS homolog, forms a complex with Msh2p to repair insertion-deletion mispairs ; redundant with Pms3 /Msh6p in repair of insertion-deletion YCR092C -0.48347992 0.038813832 -0.187584544 0.049491282 MSH3 mispairs YCR094W -0.16620501 0.261431398 -0.285105037 0.126496125 CDC50 involved in cell cycle YCR095C -0.36993185 0.052374615 -0.800845227 0.01132401 similarity to Saccharomyces kluyveri strain NRRL Y-12651 YCR096C -0.17214299 0.08095577 -0.74149727 0.107177301 A2 Regulatory protein MATa2p (no known function) ; sequence is the same as the last 119 residues of MATalpha2p YCR098C -1.94254856 0.018159179 -0.393662324 0.013573311 GIT1 permease involved in the uptake of glycerophosphoinositol (GroPIns) YCR099C 0.284621132 0.587360871 -0.310666219 0.044815525 strong similarity to Pep1p, VTH1p and VTH22p YCR100C -0.07674588 0.887484474 -0.422956421 0.022677252 strong similarity to Pep1p, VTH1p and VTH22p YCR101C 0.158376681 0.673935418 -0.386967163 0.237267841 strong similarity to Pep1p, VTH1p and VTH22p YCR102C -0.59362917 0.061112722 0.13615273 0.398950074 similarity to C.carbonum toxD gene/Alcohol dehydrogenase YCR102W-A -1.05493453 0.075783869 -0.145376569 0.633612528 similarity to other hypothetical yeast proteins YCR104W -0.14532619 0.619474161 0.715360618 0.036495203 PAU3 similar to bovine alcohol dehydrogenase YCR105W -0.01632391 0.932642718 0.392672763 0.004834737 strong similarity to alcohol dehydrogenases YCR106W -0.41795945 0.014914755 0.013245331 0.917591091 similarity to transcription factor YCR107W -0.58514312 0.007381135 -0.02979112 0.846921522 AAD3 hypotetical aryl-alcohol dehydrogenase YDL001W 0.1360533 0.220182656 -0.409283669 0.243922278 similarity to hypothetical protein YFR048w, YDR282c and S.pombe hypothetical protein SPAC12G12.14 YDL002C -0.12418124 0.445376635 -0.83210355 0.043303102 NHP10 HMG1-box containing protein YDL003W 0.813712227 0.256263265 -0.192665886 0.54619669 MCD1 involved in mitosis, similar to pombe Rad21 YDL004W -0.42881752 0.299618391 0.109365679 0.155864744 ATP16 ATP synthase delta subunit YDL005C -0.08304329 0.577141277 -0.545539827 0.121383189 MED2 Stoichiometric member of mediator complex YDL006W 0.100381614 0.450165922 -0.215091024 0.145233855 PTC1 serine-threonine protein phosphatase YDL007W 0.055197529 0.763800874 -0.285700588 0.066605889 RPT2 (putative) 26S protease subunit YDL008W 0.018487675 0.921955505 -0.108159954 0.059471716 APC11 subunit of the anaphase promoting complex (APC) YDL009C -0.04094151 0.778351459 -0.345898871 0.014787019 questionable ORF YDL010W -0.41777237 0.133882837 -0.291335413 0.185763163 similarity to hypothetical protein YBR014c and glutaredoxins YDL011C 0.383585303 0.508087685 0.204121684 0.308381685 questionable ORF YDL012C 0.526862852 0.001410657 0.481652605 0.091998147 strong similarity to hypothetical protein YBR016w and YDR210w YDL013W 0.175418718 0.600074562 -0.021852544 0.90099832 HEX3 involved in hexose metabolism YDL014W 1.217127816 0.017378388 0.23986913 0.014376917 NOP1 nucleolar protein, homologous to mammalian fibrillarin YDL015C 0.333796754 0.343676045 0.248456774 0.077970126 similarity to rat synaptic glycoprotein SC2 YDL016C 0.754175511 0.124127131 0.607221245 0.02758052 questionable ORF YDL017W 0.719726282 0.007000915 -0.19292024 0.307522 CDC7 serine /threonine protein kinase YDL018C -0.12000345 0.219699484 -0.108893169 0.475777536 ERP3 p24 protein involved in membrane trafficking YDL019C -0.91686783 0.02784184 0.07094429 0.226825342 OSH2 OSbp Homologue (OSBP stands for Oxysterol binding protein) YDL020C -0.47787199 0.075415567 -0.309636299 0.058940539 RPN4 ubiquitin-mediated 26S proteasome subunit YDL021W -2.17789304 0.000219858 -0.684971798 0.016677876 GPM2 phosphoglycerate mutase, involved in glycolysis YDL022W -2.23984101 0.000421514 -0.162893838 0.214924251 GPD1 glycerol-3-phosphate dehydrogenase YDL023C -1.85019518 0.011392282 0.167938137 0.445908394 questionable ORF YDL024C -0.97330092 0.013770959 0.064090577 0.814963653 DIA3 strong similarity to acid phosphatase/Digs Into Agar YDL025C -0.01419232 0.969460342 -0.007939275 0.893996806 similarity to probable protein kinase NPR1 YDL026W -1.02525755 0.010350438 0.078784311 0.565144044 questionable ORF YDL027C -1.0092284 0.003268983 -0.057018308 0.368915526 hypothetical protein serine /threonine /tyrosine protein kinase (dual specificity), able to autophosphorylate as well as act on Mad1p. A mutation predicted to abolish YDL028C -0.10795617 0.562733286 -0.509010424 0.064539266 MPS1 kinase function eliminates in vitro protein kinase activity and behaves like a null mutation in vivo. YDL029W -0.07991371 0.719226522 -0.264988039 0.175733942 ARP2 actin-related protein YDL030W -0.038229 0.698751743 -0.280228656 0.090720961 PRP9 RNA splicing factor YDL031W 0.823862693 0.005019395 -0.437194776 0.07643666 DBP10 DEAD box protein 10/similar to RNA helicases YDL032W -0.65316029 0.213772535 0.25162771 0.709685364 questionable ORF YDL033C 0.179488184 0.490492304 0.258496364 0.13763763 similarity to H.influenzae hypothetical protein HI0174 YDL034W 0.089270732 0.880377639 0.1615131 0.531364198 questionable ORF YDL036C 0.014759741 0.890117691 -0.315568668 0.105894724 strong similarity to RIB2 protein YDL037C 0.559271771 0.65741304 0.23717564 0.213658447 strong similarity to glucan 1,4-alpha-glucosidase YDL038C 1.323159933 0.102415042 0.625900249 0.013186053 similarity to mucin proteins YDL039C 1.608493686 0.392720926 0.764200109 0.126210299 PRM7 pheromone-regulated membrane protein YDL040C 0.633411354 0.048208169 -0.079552133 0.100518051 NAT1 N-terminal acetyltransferase YDL041W 0.174288224 0.642503898 0.258375777 0.62589572 KRE26 Killer toxin REsistant YDL042C -0.10118825 0.794706138 -0.073951013 0.456369277 SIR2 regulator of silencing at HML, HMR, telomeres, and rDNA YDL043C -0.52563075 0.221880004 -0.541711335 0.05787954 PRP11 snRNA-associated protein YDL044C 0.10286614 0.603559734 -0.643456132 0.015415234 MTF2 involved in mRNA splicing YDL045C -0.12765433 0.444295987 0.100242513 0.111353338 FAD1 FAD synthetase YDL045W-A 0.852422552 0.083253409 0.092071622 0.621864993 MRP10 homologous to Yml37p, component of the 37 S subunit of mitochondrial ribosomes YDL046W 0.389095959 0.168440875 0.785538487 0.124999845 hypothetical protein YDL047W -0.23823088 0.287941087 0.196120856 0.167320397 SIT4 type 2A related protein phosphatase YDL048C -0.99820765 0.086957301 0.056948096 0.846017102 STP4 involved in tRNA splicing YDL049C -1.07021664 0.025207224 -0.199903487 0.363225697 KNH1 KRE9 homolog YDL050C 0.972964866 0.038218139 -0.383737321 0.040940004 questionable ORF YDL051W 0.926989603 0.08680128 -0.409082606 0.039835976 LHP1 RNA binding protein similar to human La autoantigen YDL052C 0.593664795 0.080781334 0.423615661 0.083231637 SLC1 putative 1-acyl-sn-gylcerol-3-phosphate acyl transferase YDL053C 0.286154473 0.157281354 -0.402547543 0.029444928 hypothetical protein YDL054C 0.512041385 0.399109838 0.326679615 0.57679833 hypothetical protein YDL055C 2.638318771 0.396372724 0.381406488 0.089838919 PSA1 mannose-1-phosphate guanyltransferase, GDP-mannose pyrophosphorylase YDL056W -0.20889058 0.164897414 -0.130549932 0.243231736 MBP1 transcription factor YDL057W 0.144105209 0.752696738 0.004234548 0.977190884 hypothetical protein YDL058W -0.0941124 0.672960832 -0.15243792 0.426707952 USO1 Integrin analogue gene YDL059C -0.65221223 0.142894576 -0.147626533 0.451259491 RAD59 The RAD59 gene product has homology to the Rad52 protein. YDL060W 1.034685519 0.030638507 -0.336745546 0.114774837 similarity to C.elegans hypothetical protein YDL061C 0.916519867 0.059769261 0.896321501 0.017545271 RPS29B Ribosomal protein S29B (S36B) (YS29) YDL062W 0.58883272 0.056815981 -0.232949174 0.322514661 questionable ORF YDL063C 1.328826069 0.162840609 -0.563186768 0.084177112 weak similarity to human estrogen-responsive finger protein YDL064W 0.708024303 0.018337768 0.1485291 0.275721116 UBC9 ubiquitin-conjugating enzyme YDL065C -0.06517681 0.636245286 -0.373826531 0.192819099 PEX19 40 kDa farnesylated protein associated with peroxisomes YDL066W -0.66771117 0.032746589 0.37912913 0.189582732 IDP1 Mitochondrial form of NADP-specific isocitrate dehydrogenase YDL067C -0.27072207 0.172636549 0.191353465 0.334545661 COX9 Subunit VIIa of cytochrome c oxidase YDL068W -0.54170324 0.265906018 -0.12231526 0.284518572 questionable ORF YDL069C -0.1692121 0.633309641 -0.545439906 0.12016737 CBS1 translational activator of cytochrome b YDL070W -0.01258233 0.963502322 -0.496672642 0.103736094 BDF2 Bromodomain protein, homolog of Bdf1 YDL071C 0.683244197 0.04764493 0.43366029 0.256079488 questionable ORF YDL072C 0.334945833 0.433315609 0.397777848 0.134447189 weak similarity to hypothetical protein YMR040w YDL073W 0.365624068 0.216148262 -0.175677529 0.135267149 weak similarity to Cyprinus carpio calcium channel protein YDL074C 0.331837013 0.279825701 -0.715733181 0.020643802 BRE1 weak similarity to spindle pole body protein NUF1 YDL075W 1.734797453 0.059763772 -0.16965972 0.560638925 RPL31A Ribosomal protein L31A (L34A) (YL28) YDL076C 0.604763082 0.043842493 -0.006097819 0.852662544 hypothetical protein YDL077C 0.181971946 0.199757304 -0.261035382 0.240744248 VAM6 involved in vacuolar morphogenesis YDL078C -0.58680541 0.122161553 0.177881461 0.436845774 MDH3 malate dehydrogenase YDL079C -0.27261408 0.397037282 0.394391824 0.091743863 MRK1 MDS1 related protein kinase YDL080C 0.648126243 0.118077486 -0.140476461 0.073749067 THI3 alpha-ketoisocaproate decarboxylase YDL081C 2.308299563 0.013332031 0.745970418 0.029550652 RPP1A Acidic ribosomal protein P1A (YP1alpha) (A1) YDL082W 1.546588088 0.00398878 -0.104410618 0.59360929 RPL13A Ribosomal protein L13A YDL083C 1.912603939 0.019191167 0.226168195 0.025123929 RPS16B Ribosomal protein S16B (rp61R) YDL084W 0.4594664 0.336090724 -0.160123822 0.015036567 SUB2 RNA helicase YDL085W -2.36621696 0.001212022 0.187522021 0.517938498 strong similarity to NADH dehydrogenase (ubiquinone) YDL086W -0.53539597 0.024201526 0.397887179 0.094136229 similarity to hypothetical Synechocystis protein YDL087C -0.13839079 0.603731988 0.048412355 0.893219661 LUC7 (putative) involved in mRNA processing YDL088C 0.371630982 0.01544691 0.04623587 0.621390657 ASM4 suppressor of temperature-sensitive mutations in Pol3p/Nuclear pore complex protein YDL089W -0.62138023 0.013528896 0.301911153 0.067740118 hypothetical protein YDL090C -0.52841019 0.032167518 0.076784202 0.627782726 RAM1 beta subunit of farnesyltransferase YDL091C -1.62532247 0.002709346 -0.345781127 0.044337665 weak similarity to mouse FAF1 protein YDL092W 0.634068878 0.079242332 -0.30839553 0.281821756 SRP14 Signal recognition particle subunit YDL093W -0.7839912 0.008683331 0.267040518 0.170564413 PMT5 dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase YDL094C -0.27053916 0.205071132 -0.00947456 0.971160009 questionable ORF YDL095W -0.1308348 0.501835574 0.396132864 0.082577726 PMT1 dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase YDL096C 0.148210834 0.871122316 0.624711025 0.095592563 questionable ORF YDL097C -0.02842374 0.895239664 -0.352623757 0.033915161 RPN6 Subunit of the regulatory particle of the proteasome YDL098C 0.117448367 0.714449523 -0.755396428 0.086540907 SNU23 Putative RNA binding zinc finger protein YDL099W -0.14315556 0.421844718 -0.817588706 0.054587846 weak similarity to myosin heavy chain proteins YDL100C -0.17008295 0.375364625 -0.25948525 0.034901867 similarity to E.coli arsenical pump-driving ATPase YDL101C 0.057389406 0.852544741 -0.178459665 0.289408735 DUN1 protein kinase YDL102W 0.429314165 0.014365988 0.067648587 0.357319886 CDC2 largest and catalytic subunit of DNA polymerase III (delta) YDL103C -0.43127486 0.149074668 -0.130979718 0.313073353 QRI1 UDP-N-acetylglucosamine pyrophosphorylase YDL104C -0.60142075 0.081328599 -0.280988715 0.046140248 QRI7 similar to H.influenzae sialoglycoprotease YDL105W -0.5886175 0.101118626 -0.167016637 0.43440265 QRI2 protein of unknown function YDL106C 0.106760551 0.529386853 -0.154022628 0.032931351 PHO2 Homeobox-domain containing transcription fractor which is a positive regulator of PHO5 and other genes. YDL107W -0.11140599 0.495411191 -0.578986844 0.067276656 MSS2 cox1 pre-mRNA splicing factor YDL108W -0.20730272 0.262018154 -0.268910375 0.068086427 KIN28 serine-threonine kinase, subunit of transcription factor TFIIK, a subcomplex of TFIIH YDL109C -0.80513432 0.099246077 0.053346712 0.564387067 lipase family protein containing serine active site YDL110C -0.51317772 0.168342914 -0.179036101 0.063827147 hypothetical protein YDL111C 1.16291458 0.012009052 0.274099734 0.285734157 RRP42 Component of the exosome 3->5 exoribonuclease complex with Rrp4p, Rrp41p, Rrp43p and Dis3p (Rrp44p). YDL112W 0.212169886 0.316664227 -0.042100125 0.687355311 TRM3 tRNA (Gm18) ribose methylase YDL113C -0.7481118 0.032269115 -0.550342252 0.135214166 similarity to hypothetical protein YDR425w YDL114W -0.10708913 0.764458558 0.456558706 0.345340836 weak similarity to Rhizobium nodulation protein nodG YDL115C -0.38270161 0.075406392 -0.694573277 0.021211445 hypothetical protein YDL116W 0.301172293 0.112455168 -0.18255526 0.06798221 NUP84 Protein with homology to mammalian Nup107p YDL117W 0.903460332 0.207110314 -0.047990172 0.673448623 CYK3 involved in CYtoKinesis YDL118W 0.628280079 0.087222954 -0.176375821 0.70654144 questionable ORF YDL119C 0.452444858 0.225415602 -0.213990714 0.059801652 similarity to bovine Graves disease carrier protein YDL120W 0.092569521 0.782716083 -0.169469045 0.091813854 YFH1 mitochondrial protein that regulates mitochondrial iron accumulation YDL121C 0.37361887 0.159729704 -0.374310663 0.109228217 hypothetical protein YDL122W 0.908685115 0.021761557 -0.405311128 0.034639539 UBP1 Ubiquitin-specific protease YDL123W 0.408394411 0.540582872 0.324832682 0.113866739 similarity to hypothetical protein YJL151c YDL124W -1.16317913 0.00602663 0.428474768 0.154348525 similarity to aldose reductases YDL125C -0.03379696 0.824601881 0.486990087 0.192150353 HNT1 similarity to protein kinase C inhibitor-I YDL126C -0.13456205 0.138641128 -0.043236507 0.671019613 CDC48 microsomal ATPase YDL127W 0.301438351 0.405353385 0.272462135 0.083906357 PCL2 G1 cyclin YDL128W -0.25552869 0.321427153 0.624347403 0.108734058 VCX1 vacuolar H+ /Ca2+ exchanger YDL129W -0.32143328 0.272821191 0.010593839 0.960449276 hypothetical protein YDL130W 1.828980435 0.017651205 0.438306831 0.011905829 RPP1B Ribosomal protein P1B (L44') (YP1beta) (Ax) YDL130W-A -1.45668041 0.004378691 -0.304107211 0.162527725 STF1 ATPase stabilizing factor YDL131W 1.325487503 0.309093892 0.398346251 0.114531272 LYS21 homocitrate synthase, highly homologous to YDL182W YDL132W -0.20318148 0.31224688 -0.262237622 0.05939558 CDC53 involved in G1 cyclin degradation YDL133W 0.347032801 0.369790558 -0.126822945 0.191932928 hypothetical protein YDL134C -0.47661537 0.094519655 -0.102178215 0.43566819 PPH21 serine-threonine protein phosphatase 2A YDL135C 0.182589017 0.165689078 -0.549611217 0.091923039 RDI1 Rho GDP dissociation inhibitor YDL136W 0.519972334 0.169363829 -0.586988481 0.092290158 RPL35B Ribosomal protein L35B YDL137W 0.423012142 0.154126337 -0.041985843 0.684144492 ARF2 ADP-ribosylation factor 2 YDL138W -0.43058681 0.027968482 0.278347572 0.191655691 RGT2 glucose permease YDL139C -0.35807454 0.20303989 -0.325932256 0.071237566 SCM3 Suppressor of chromosome missegregation YDL141W -0.56412825 0.100108697 0.176092537 0.290827663 BPL1 Biotin:apoprotein ligase YDL142C -0.63485391 0.014403083 0.056146661 0.521872646 CRD1 Cardiolipin synthase YDL143W 0.352461737 0.434555147 -0.169586735 0.018557114 CCT4 component of chaperonin complex YDL144C -0.36015322 0.022006768 0.370384435 0.228765515 hypothetical protein YDL145C -0.05797091 0.87617395 0.207658465 0.019681022 COP1 alpha subunit of the coatamer complex ; gamma-alpha-COP YDL146W 0.108465992 0.805769207 -0.22445922 0.016962723 weak similarity to Orc3p YDL147W 0.021536027 0.928632721 -0.526445112 0.18452506 RPN5 Subunit of the regulatory particle of the proteasome YDL148C 0.619219623 0.10753226 -0.949341861 0.027628925 similarity to human mRNA clone RES4-25 YDL149W -0.43503709 0.303753118 0.14286093 0.513223935 APG9 Integral membrane protein YDL150W 1.498750605 0.209194067 -0.468430643 0.044590875 RPC53 RNA polymerase III (C) subunit, homologus to human BN51 protein YDL151C 0.809575869 0.191172207 0.028189514 0.618050895 questionable ORF YDL152W 0.784222347 0.036006965 -0.555624287 0.047028449 questionable ORF YDL153C 0.406384202 0.062317418 -1.118773438 0.018600807 SAS10 nuclear protein involved in silencing YDL154W -0.10567891 0.814844214 -0.028282967 0.909084842 MSH5 MutS homolog involved in chromosome exchange YDL155W 0.590046199 0.011213664 -0.087214252 0.590242238 CLB3 G(sub)2-specific B-type cyclin YDL156W -0.23602455 0.456205937 0.055028366 0.770564649 weak similarity to Pas7p YDL157C 0.141937273 0.673118667 -0.23166741 0.065137012 hypothetical protein YDL158C 0.116794274 0.624666272 0.035977792 0.325584689 questionable ORF YDL159W -0.3590388 0.156765186 -0.008152833 0.905636851 STE7 MEK homolog YDL160C 0.07876036 0.65376352 0.314204232 0.069164556 DHH1 (putative) DEAD box RNA helicase YDL161W -0.05391601 0.686583889 -0.259938401 0.316152733 ENT1 Ent1p YDL162C 0.146612736 0.724381788 1.642680121 0.431119662 hypothetical protein YDL163W 0.190818476 0.590889586 -0.128223584 0.732772579 questionable ORF YDL164C -0.26679883 0.417581124 0.009539701 0.964252489 CDC9 DNA ligase YDL165W -0.10369019 0.31696461 0.213793848 0.112408902 CDC36 nuclear protein that negatively regulates basal transcription YDL166C 1.007255038 0.126517165 -0.175164626 0.143857389 weak similarity to Pyrococcus horikoshii hypothetical protein PHBJ019 YDL167C 1.579071749 0.050452599 -0.065875562 0.682902389 NRP1 Asparagine-rich protein YDL168W -0.26708089 0.359881509 0.088105719 0.405226076 SFA1 Long-chain alcohol dehydrogenase (glutathione-dependent formaldehyde dehydrogenase) YDL170W -0.06390677 0.729886002 -0.382276487 0.058097302 UGA3 zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type YDL172C 0.063477954 0.863184503 0.080716474 0.553781991 questionable ORF YDL173W -0.34661006 0.247676493 -0.51427273 0.127086801 hypothetical protein YDL175C 0.18179685 0.28040713 -0.252502053 0.242408227 strong similarity to hypothetical protein YIL079c and weak similarity to cellular nucleic acid binding proteins YDL176W -0.84150439 0.012817077 -0.397517704 0.138905886 hypothetical protein YDL177C 0.70095935 0.087122601 -0.546722446 0.030264811 similarity to hypothetical protein YCR059c YDL178W 0.152736347 0.67103998 -0.141893234 0.161495958 AIP2 D-Lactate Dehydrogenase (Cytochrome) YDL179W 0.595904308 0.484834362 0.073558627 0.407549935 PCL9 cyclin like protein interacting with Pho85p YDL180W 0.167736634 0.662254347 0.23944357 0.045905187 hypothetical protein YDL181W -1.74369441 0.001755971 0.554533535 0.120770193 INH1 ATPase inhibitor YDL182W 1.295411835 0.310672555 0.429485016 0.060176286 LYS20 homocitrate synthase, highly homologous to YDL131W YDL183C 0.002045373 0.991083146 -0.065021409 0.28557679 weak similarity to S.pombe hypothetical protein SPAC23H3 YDL184C -0.02689704 0.95241093 -0.175430861 0.572890186 RPL41A Ribosomal protein L41A (YL41) (L47A) YDL185W -0.92830844 7.52782E-05 0.207326754 0.280076799 TFP1 vacuolar ATPase V1 domain subunit A (69 kDa) YDL186W 1.452018663 0.05972002 0.35308334 0.057784377 hypothetical protein YDL187C 1.573174276 0.174056852 0.418448668 0.079344725 questionable ORF YDL188C -0.55452206 0.063016955 -0.019929927 0.90318706 PPH22 serine-threonine protein phosphatase 2A YDL189W 0.348378665 0.094781314 -0.015402366 0.943444149 hypothetical protein YDL190C 0.048854131 0.794255268 0.430889635 0.042403567 UFD2 ubiquitin fusion degradation protein YDL191W 0.617598406 0.254340889 -0.560365742 0.036213696 RPL35A Ribosomal protein L35A YDL192W 0.905222946 0.321040607 -0.274910193 0.022639443 ARF1 ADP-ribosylation factor YDL193W -0.25214993 0.070810357 -0.193347977 0.11548141 similarity to N.crassa hypothetical 32 kDa protein YDL195W -0.33996636 0.314911932 0.660612937 0.041363009 SEC31 Component (p150) of COPII coat of secretory pathway vesicles YDL196W -0.2807457 0.421683454 1.061830277 0.002456133 hypothetical protein YDL197C -0.73333695 0.031900681 0.008681113 0.970813317 ASF2 Anti-silencing protein, involved in transcription YDL198C 0.806399253 0.216854159 0.15959481 0.321457176 YHM1 (putative) mitochondrial carrier protein YDL199C -0.3035713 0.468247117 0.244285048 0.006582327 similarity to sugar transporter proteins YDL200C -0.55290351 0.019078443 -0.457047236 0.017060942 MGT1 6-O-methylguanine-DNA methylase YDL201W 0.135300073 0.488686798 -0.219848437 0.147447463 putative methyltransferase YDL202W 0.27351953 0.053889959 -0.59430976 0.033975815 MRPL11 Mitochondrial ribosomal protein MRPL11 (YmL11) YDL203C -0.56632429 0.075826703 0.104979638 0.595739983 similarity to Skt5p YDL204W -2.04612452 0.001088483 0.196659039 0.218791016 similarity to hypothetical protein YDR233c YDL205C 0.706061277 0.103537875 0.088052421 0.385893494 HEM3 phorphobilinogen deaminase (uroporphyrinogen synthase), the third step in heme biosynthesis YDL206W -0.61199876 0.026311397 -0.204292372 0.285905821 weak similarity to transporter proteins YDL207W -0.06622244 0.590819544 -0.278230341 0.008368752 GLE1 Nuclear-export-signal (NES)-containing protein YDL208W 1.303474134 0.100387294 -0.607501604 0.063118132 NHP2 HMG-like nuclear protein YDL209C 0.180697076 0.215999809 -0.405044733 0.033814356 similarity to hypothetical S. pombe protein YDL210W -1.79114688 0.009972271 0.074275731 0.752955777 UGA4 GABA-specific transport protein YDL211C 1.219122075 0.036953354 0.480893434 0.05826958 similarity to hypothetical protein YNL176c YDL212W 0.399558887 0.448346454 -0.058448906 0.297279347 SHR3 Integral membrane component of the endoplasmic reticulum YDL213C 0.78646459 0.052548444 -0.458601818 0.091576813 has an RNA recognition domain in the N-terminal region YDL214C -0.34455264 0.465745662 0.119787414 0.385989426 strong similarity to putative protein kinase NPR1 YDL215C 0.691585049 0.550809764 -0.11910891 0.024926696 GDH2 NAD-dependent glutamate dehydrogenase YDL216C -0.7996671 0.003368148 -0.672510033 0.027396822 similarity to Jun activation domain binding protein homologue of A. thaliana YDL217C 0.398376258 0.233654505 -0.05775963 0.585115792 TIM22 Mitochondrial inner membrane protein involved in import YDL218W -0.6796419 0.306490896 0.578567451 0.101426901 weak similarity to hypothetical protein YNR061c YDL219W 0.38788163 0.472227267 -0.591291278 0.093936303 strong similarity to S.equisimilis hypothetical protein YDL220C -0.50093002 0.164046565 0.21723749 0.046993638 CDC13 binds to single-stranded TG1-3 telomere G-tails YDL221W -0.07474845 0.853978136 0.74166789 0.088276449 questionable ORF YDL222C -0.52423124 0.495336672 0.883755411 0.089155614 strong similarity to hypothetical protein YNL194c and similarity to YML052w YDL223C -0.93550172 0.167643558 0.48016019 0.192040142 weak similarity to mucin YDL224C -0.48976823 0.173553649 0.548573819 0.089645396 WHI4 Possible RNA binding protein. Homolog of Whi3. YDL225W 0.383302397 0.041825056 -0.544262354 0.09950373 SHS1 Septin homolog YDL226C -0.0623909 0.862375335 -0.239541383 0.055931012 GCS1 ADP-ribosylation factor GTPase-activating protein (ARF GAP) YDL227C -0.67007445 0.028838514 -0.277032432 0.260998503 HO Homothallic switching endonuclease YDL230W 0.396836517 0.510923426 0.290638395 0.173789663 similarity to A.klebsiana glutamate dehydrogenase YDL231C -0.33323203 0.270377017 0.026197314 0.797759383 BRE4 null mutant is sensitive to brefeldin A YDL232W 0.556385897 0.171765558 0.665396226 0.05373755 OST4 3.6-kDa protein, probably membrane-located YDL233W 0.30360855 0.02164613 0.216259905 0.088403983 hypothetical protein YDL234C 0.292553026 0.621131889 -0.305387079 0.013482185 GYP7 GTPase-activating protein YDL235C 0.908728072 0.280576046 -0.137079118 0.372324388 YPD1 Two-component phosphorelay intermediate YDL236W 0.368901914 0.662198269 -0.264931602 0.06164024 PHO13 p-nitrophenyl phosphatase YDL237W -0.47558101 0.235763402 0.126188973 0.512781998 hypothetical protein YDL238C 0.489471344 0.521597978 0.091636649 0.79193763 similarity to E.coli hypothetical protein and to chlorohydrolases YDL239C -1.30178901 0.004163185 -0.200762225 0.16337951 hypothetical protein YDL240W 0.078616273 0.760143959 -0.096099833 0.149062819 LRG1 Protein similar to LIM-domain proteins and to rho /rac GTPase-activating family of proteins YDL241W 1.34253034 0.008301684 0.016268961 0.905450236 hypothetical protein YDL242W 0.305363323 0.380731166 0.30630974 0.308433355 strong similarity to hypothetical protein YPR079w YDL243C -0.5312573 8.97975E-05 -0.023824921 0.669000201 AAD4 Hypothetical aryl-alcohol dehydrogenase YDL244W 4.757249417 0.379678093 0.509832996 0.420518011 THI13 strong similarity to Thi5p, YJR156c, YNL332w and A.parasiticus, S.pombe nmt1 protein YDL245C -1.0651814 0.002019619 0.132359563 0.452055658 HXT15 Hexose transporter YDL246C -0.73395831 0.034251545 -0.714909276 0.033808416 strong similarity to Sor1p YDL247W 0.401987656 0.293750243 0.276719361 0.279349369 strong similarity to sugar transport proteins YDL248W 0.031998334 0.938237782 -0.106851462 0.451324374 COS7 similar to other subtelomerically-encoded proteins YDR001C -1.20815299 9.87295E-05 0.006394819 0.965736383 NTH1 neutral trehalase YDR002W 0.875252223 0.203410784 -0.715100792 0.023215245 YRB1 nuclear GTPase-activating protein for Ran YDR003W -0.54686716 0.004011308 0.084778701 0.218758662 strong similarity to hypothetical protein YBR005w YDR004W -0.6623851 0.142028678 -0.223797725 0.19376891 RAD57 RecA homolog (similar to DMC1, RAD51, and RAD55), interacts with Rad 55p by two-hybrid analysis YDR005C -1.36268028 0.004459171 -0.544239287 0.006671934 MAF1 Mod5 protein sorting YDR006C 0.192403786 0.669220751 0.088696721 0.465921379 SOK1 high copy suppressor of cAMP-dependent protein kinase A temperature-sensitive mutations YDR007W 0.116952808 0.780421294 1.570697406 0.023937568 TRP1 n-(5'-phosphoribosyl)-anthranilate isomerase YDR008C 0.10768243 0.727881468 1.529049358 0.07013796 questionable ORF YDR009W -0.46284599 0.233771707 0.121735826 0.595205793 GAL3 involved in galactose induction of GAL genes YDR010C 0.747124934 0.356766501 3.079566864 0.406922635 hypothetical protein YDR011W -0.72437167 0.003023051 0.473283506 0.166712532 SNQ2 ABC transporter YDR012W 1.365812533 0.064550535 0.217296272 0.215143703 RPL4B Ribosomal protein L4B (L2B) (rp2) (YL2) YDR013W 0.478781848 0.126973108 -0.370299789 0.080020105 similarity to human hypothetical KIAA0186 protein YDR015C 0.267785814 0.113754648 0.174031169 0.283608625 weak similarity to chicken neurofilament triplet M protein YDR016C 0.085411603 0.699040544 -0.143612955 0.413610553 DAD1 Duo1 And Dam1 interacting ; localized to intranuclear spindles and spindle pole bodies YDR018C -1.28502098 0.000615924 -0.142919399 0.708620643 strong similarity to hypothetical protein YBR042c YDR019C 1.049665197 0.281083898 -0.179809466 0.152227846 GCV1 glycine cleavage T protein (T subunit of glycine decarboxylase complex YDR020C 0.766644855 0.097157641 -0.361945612 0.015562402 weak similarity to uridine kinases and phosphoribulokinases YDR021W 0.521637724 0.162057332 -0.477787446 0.067447341 FAL1 DEAD-box protein, putative RNA helicase YDR022C -0.99694739 0.002358519 -0.303556544 0.148573782 CIS1 involved in microtubule assembly YDR023W 0.210567307 0.56540803 -0.62233489 0.025381772 SES1 seryl-tRNA synthetase YDR024W 0.400137581 0.264560109 -0.023319302 0.801886668 hypothetical protein YDR025W 1.14703072 0.119007804 0.332549467 0.167976165 RPS11A Ribosomal protein S11A (S18A) (rp41A) (YS12) YDR026C 0.462065751 0.032862106 -1.050862095 0.023255976 strong similarity to DNA-binding protein Reb1p YDR028C -0.39131571 0.006427893 -0.474575704 0.009553515 REG1 regulator of phosphatase Glc7p, involved in glucose repression YDR029W 0.623463595 0.383805535 0.039165966 0.861826825 hypothetical protein YDR030C -0.3915176 0.095675988 -0.614657395 0.054064772 RAD28 involved in DNA repair, has WD repeats YDR031W -0.58603479 0.002678541 -0.189380852 0.102031839 hypothetical protein YDR032C -0.26938502 0.140904224 0.497382815 0.17765195 PST2 Protoplasts-SecreTed protein ; the gene product was detected among the proteins secreted by regenerating protoplasts Membrane protein Related to Hsp30p ; Localized by immunofluorescence to cell membranes, primarily the plasma membrane. A punctuate YDR033W 0.140284247 0.704384726 0.146789147 0.529131647 MRH1 immunofluorescence pattern was observed within cell buds. The nuclear envelope, but not the vacuole or mitochondrial membrane YDR034C 0.219685087 0.718996654 -0.16519193 0.017013893 LYS14 transcription factor involved in lysine biosynthesis YDR034C-A 0.084389188 0.851245036 -0.224333129 0.038772575 identified by SAGE expression analysis YDR034W-B 0.555897751 0.5291951 0.328459872 0.115295011 DAHP synthase ; a.k.a. phospho-2-dehydro-3-deoxyheptonate aldolase, phenylalanine-inhibited ; phospho-2-keto-3-deoxyheptonate aldolase ; YDR035W 0.194887176 0.571907742 -0.28802562 0.053158841 ARO3 2-dehydro-3-deoxyphosphoheptonate aldolase ; 3-deoxy-D-arabine-heptulosonate-7-phosphate synthase YDR036C 0.129283775 0.673432252 0.087454249 0.511272076 similarity to enoyl CoA hydratase YDR037W 1.278983148 0.141915776 -0.056339529 0.357760364 KRS1 lysyl-tRNA synthetase YDR038C -0.4719567 0.118268335 0.273467671 0.192866649 ENA5 Na(+) ATPase YDR039C -0.5462513 0.054339517 0.275283261 0.151392176 ENA2 plasma membrane protein ; putative Na+ pump ; P-type ATPase YDR040C -0.48398559 0.143005908 0.231572772 0.217763241 ENA1 Plasma membrane Na+ pump ; P-type ATPase YDR041W -0.5532923 0.150874186 -0.235426709 0.175352313 RSM10 protein of the small subunit of the mitochondrial ribosome YDR042C 0.067044436 0.880261945 0.070517572 0.48752248 hypothetical protein YDR043C -0.13300202 0.52097033 -0.167068055 0.142059202 NRG1 transcriptional repressor which can bind to UAS-1 in the STA1 promoter and which can interact with Ssn6p YDR044W 0.226294076 0.679222554 0.507142434 0.165908937 HEM13 Coproporphyrinogen III oxidase YDR045C 1.08571073 0.174673504 -0.373094463 0.063397669 RPC11 TFIIS-like small Pol III subunit C11 YDR046C 0.084269542 0.858615054 0.177224707 0.234078881 BAP3 Valine transporter YDR047W 0.506328447 0.038601615 0.08344245 0.589439918 HEM12 uroporphyrinogen decarboxylase YDR048C -0.05196993 0.93986346 0.432534785 0.578340595 questionable ORF YDR049W 0.02809158 0.905778633 -0.474509987 0.107396507 similarity to C.elegans K06H7.3 protein YDR050C 1.547383023 0.348987343 0.61695954 0.050707247 TPI1 triosephosphate isomerase YDR051C -0.68725518 0.019573053 -0.455166365 0.076931111 similarity to hypothetical A. thaliana protein BAC F7G19 YDR052C 0.844428057 0.015152142 -0.140823648 0.4904764 DBF4 Regulatory subunit of Cdc7p-Dbf4p kinase complex YDR053W 0.142877998 0.812398002 0.109234865 0.783649149 questionable ORF YDR054C 0.061561643 0.799020445 -0.028283433 0.750139235 CDC34 ubiquitin-conjugating enzyme, E2 YDR055W 2.44539686 0.357606499 0.40964352 0.284046982 PST1 The gene product has been detected among the proteins secreted by regenerating protoplasts YDR056C 0.591025664 0.466359648 0.012253766 0.924154381 hypothetical protein YDR057W -0.14599429 0.628561038 -0.529499989 0.002236042 weak similarity to L.lactis mleR protein YDR058C -0.66818434 0.100529704 -0.297029012 0.10581136 TGL2 Triglyceride Lipase YDR059C -0.04318585 0.880882276 0.470068232 0.258845782 UBC5 ubiquitin-conjugating enzyme YDR060W 1.329658672 0.065542303 -0.548414373 0.11480275 similarity to mouse putative CCAAT binding factor CBF1 and CBF2 YDR061W -0.04318019 0.918360964 -0.36346012 0.021932827 similarity to E.coli modF and photorepair protein phrA YDR062W 0.867350963 0.220324601 0.195965218 0.016412053 LCB2 Probable component of serine palmitoyltransferase, which catalyzes the first step in biosynthesis of long-chain sphingolipids YDR063W -0.76028946 0.03988093 -0.059650539 0.41399261 weak similarity to glia maturation factor beta YDR064W 1.542230434 0.055859956 0.376037692 0.013764765 RPS13 Ribosomal protein S13 (S27a) (YS15) YDR065W -0.43812732 0.119433964 -0.521337902 0.043427468 hypothetical protein YDR066C 0.514999152 0.039428234 0.000641623 0.996159507 similarity to hypothetical protein YER139c YDR067C 0.403265131 0.062795732 -0.264402985 0.038586121 similarity to YNL099c YDR068W 0.326556656 0.44053075 -0.943504276 0.055614156 DOS2 involved in genome stability YDR069C -0.75422855 0.032364613 0.003511031 0.979100385 DOA4 ubiquitin isopeptidase YDR070C -3.89565437 1.8649E-06 0.019198122 0.913522654 hypothetical protein YDR071C 0.326746909 0.401315156 -0.391781657 0.281122362 similarity to O.aries arylalkylamine N-acetyltransferase YDR072C 0.901127073 0.22784972 0.513528023 0.13032547 IPT1 inositolphosphotransferase 1 YDR073W 0.467540345 0.389193888 -0.243727659 0.126489088 SNF11 component of SWI /SNF global transcription activator complex YDR074W -1.46080113 0.004701094 0.23884715 0.01407825 TPS2 Trehalose-6-phosphate phosphatase YDR075W 1.028549792 0.065544849 -0.152763342 0.304872932 PPH3 protein phosphatase type 2A YDR076W -0.20556382 0.399191392 -0.098216408 0.169139027 RAD55 RecA homolog (related to DMC1, RAD51, RAD57), interacts with Rad51p and Rad57p by two-hybrid analysis YDR077W 1.1128521 0.010028767 0.818789315 0.191319729 SED1 putative cell surface glycoprotein YDR078C -0.32079972 0.081046299 -0.363344456 0.221385291 hypothetical protein YDR079W 0.205732238 0.1637856 -0.04673602 0.462786035 PET100 cytochrome c oxidase-specific assembly factor YDR080W 0.138628859 0.456489475 -0.190778968 0.2390144 VPS41 component of vacuolar membrane protein complex YDR081C 0.250672703 0.089894125 -0.286044967 0.028343182 PDC2 Asparagine and serine-rich protein YDR082W -0.79882281 0.007398495 -0.82231355 0.025656577 STN1 involved in telomere length regulation YDR083W 1.048538768 0.056845758 -0.571237095 0.137129017 nucleolar protein required for efficient processing of pre-rRNA at site A2; methyltransferase homolog YDR084C 0.167840951 0.463862107 0.533641863 0.088712384 similarity to hypothetical C.elegans protein YDR085C -0.26577884 0.564819788 -0.000240142 0.998781771 AFR1 cytoskeletal protein, similar to arrestins YDR086C 0.964724232 0.108831003 -0.325322839 0.017474553 SSS1 endoplasmic reticulum protein that is part of the Sec61 trimeric complex and the Ssh1 trimeric complex YDR087C 1.093029209 0.024459367 -0.394419488 0.116556334 RRP1 involved in rRNA processing YDR088C -0.18396633 0.051258911 -0.83209368 0.0520654 SLU7 involved in mRNA splicing YDR089W -0.59970888 0.007578221 0.225486441 0.144845196 weak similarity to Streptococcus transposase YDR090C -0.36818244 0.400776653 -0.039052463 0.306406927 weak similarity to YRO2 protein YDR091C 1.005209496 0.040446518 -0.110891708 0.282693147 RLI1 putative member of nontransporter group of ATP-binding cassette (ABC) superfamily YDR092W 0.131290593 0.296037041 0.126384265 0.038210595 UBC13 ubiquitin-conjugating enzyme YDR094W 0.551801703 0.446126384 0.829177811 0.058523864 questionable ORF YDR095C 0.55294995 0.437717435 0.397185577 0.488727796 hypothetical protein YDR096W -0.67910899 0.069475296 0.177594018 0.157277841 GIS1 putative zinc finger protein ; repressor of PHR1 transcription Homolog of the human GTBP protein, forms a complex with Msh2p to repair both single-base and insertion-deletion mispairs, redundant with YDR097C -0.22490207 0.196623771 -0.179176183 0.124517989 MSH6 Msh3p in repair of insertion-deletion mispairs YDR098C 0.785636776 0.031962428 0.057282951 0.294803224 GRX3 Protein with glutaredoxin activity YDR098C-A 0.457185037 0.453335327 -0.105163834 0.112663795 TyA gag protein. Gag processing produces capsid proteins. YDR099W -0.26351856 0.295561847 0.234629726 0.207190391 BMH2 member of conserved eukaryotic 14-3-3 gene family YDR100W 0.668533352 0.025831114 0.666594247 0.058956002 similarity to Dictyostelium development-specific membrane protein YDR101C 1.539722971 0.024871459 -0.222943583 0.332744365 weak similarity to proliferation-associated protein YDR102C 0.462629229 0.282869783 -0.242141903 0.54633374 hypothetical protein YDR103W 0.379393739 0.374610724 0.13440509 0.312901417 STE5 scaffold protein for MAP kinase cascade YDR104C 0.003137405 0.990908055 -0.244034114 0.104448716 SPO71 protein involved in spore wall formation YDR105C -0.60931762 0.033317128 -0.081659151 0.66232287 similarity to mouse hypothetical protein YDR106W -0.16692335 0.37125181 -0.332903163 0.148263715 ARP10 Actin-related protein YDR107C -0.34053483 0.289032877 0.264518538 0.243671101 strong similarity to Emp70 protein YDR108W 0.318720103 0.066121175 -0.433799342 0.039422471 GSG1 involved in meiosis YDR109C -0.48560042 0.100974577 -0.308492376 0.099468287 similarity to Mpa43p YDR110W 0.051836035 0.584635983 -0.6450296 0.059619344 FOB1 DNA replication fork blocking protein YDR111C -0.42885423 0.15526886 -0.148402542 0.452166113 strong similarity to alanine transaminase YDR112W -0.37612945 0.075429833 -0.204694202 0.347889092 questionable ORF YDR113C 0.671460009 0.10522709 -0.06828092 0.222901969 PDS1 42-kDa nuclear protein YDR114C 0.136467428 0.423700082 0.150744041 0.032711843 questionable ORF YDR115W 0.349320575 0.123737414 0.053392416 0.145180816 similarity to bacterial ribosomal L34 proteins YDR116C 0.552607992 0.11875336 -0.173352363 0.03751388 similarity to bacterial ribosomal L1 proteins YDR117C 0.050965096 0.36452597 -0.384536522 0.058925826 similarity to mouse ligatin, a trafficking receptor for phosphoglycoproteins YDR118W 0.05206907 0.892867276 -0.061386936 0.173088901 APC4 subunit of the anaphase promoting complex (APC) YDR119W 0.908003215 0.02481435 0.396780723 0.100716605 similarity to B.subtilis tetracyclin resistance YDR120C 0.270921481 0.209365611 -0.305215125 0.032526164 TRM1 N2,N2-dimethylguanosine-specific tRNA methyltransferase YDR121W -0.16709996 0.187618956 -0.47827627 0.147744908 DPB4 DNA polymerase II (epsilon) 4th subunit YDR122W -0.85214464 0.026454118 -0.103291822 0.082424128 KIN1 Serine /threonine protein kinase YDR123C 1.130996837 0.25380742 0.163152164 0.363718011 INO2 helix-loop-helix protein YDR124W -0.62275421 0.024022286 0.344401791 0.167794648 hypothetical protein YDR125C -0.31802701 0.314879864 0.05610886 0.590841908 ECM18 (putative) involved in cell wall biogenesis YDR126W 0.530524211 0.173197248 0.059098645 0.922763952 similarity to hypothetical protein YLR246w and YOL003c YDR128W -0.4643716 0.241837295 -0.103247372 0.511866485 weak similarity to Sec27p, YMR131c and human retinoblastoma-binding protein YDR129C -0.3238347 0.165664317 0.136389811 0.451242866 SAC6 fibrim homolog (actin-filament bundling protein) YDR130C -0.13213061 0.319844529 -0.481031737 0.063713244 FIN1 Cell cycle-dependent filament between nuclei YDR131C -0.20187633 0.474653843 -0.260348238 0.081078368 similarity to hypothetical protein YJL149w YDR132C 0.098286312 0.549917874 -0.155236307 0.227566495 strong similarity to hypothetical protein YLR108c YDR133C 0.03271035 0.667516068 0.711886001 0.081056806 questionable ORF YDR134C 0.080691599 0.519429204 1.089370012 0.064386573 strong similarity to Flo1p, Flo5p, Flo9p and YLR110c YDR136C 0.195265784 0.428396894 0.587253527 0.447140699 questionable ORF YDR137W -0.11722596 0.575913733 -0.566820358 0.044824916 RGP1 involved in mitotic growth YDR138W 0.763975985 0.213265281 0.010309538 0.946484139 HPR1 involved in mitosis, recombination ; similar to TOP1 across 2 regions YDR139C 0.359107222 0.066322274 -0.19784433 0.249250995 RUB1 ubiquitin-like protein YDR140W 0.818987136 0.035401721 0.129216946 0.21849309 putative methyltransferase YDR141C -0.02370197 0.906757849 0.186691526 0.035425303 DOP1 homolog of Emericella nidulans developmental regulatory gene, dopey (dopA). YDR142C 0.117963987 0.554427853 0.342528313 0.1106227 PEX7 Member of beta-transducin-related (WD-40) protein family YDR143C 0.355744664 0.348022742 0.422566127 0.026235832 SAN1 (putative) transcriptional regulator YDR144C 1.716196129 0.111577536 0.507792573 0.055896548 MKC7 aspartyl protease related to Yap3p YDR145W 0.233032013 0.201738703 -0.428850123 0.075726681 TAF61 TFIID subunit YDR146C 0.716935468 0.186514367 -0.218819758 0.496210946 SWI5 transcriptional activator YDR147W -0.13158841 0.634671383 -0.325367794 0.160316073 EKI1 Ethanolamine Kinase YDR148C -2.06296218 0.000822137 -0.013789727 0.911548181 KGD2 dihydrolipoyl transsuccinylase component of alpha-ketoglutarate dehydrogenase complex in mitochondria YDR149C 0.305613321 0.711624076 0.061090431 0.891792351 questionable ORF member of the CCCH zinc finger protein family that has two or more repeats of a novel zinc finger motif consisting of Cys and His residues in YDR151C 0.35366165 0.109943031 0.006231723 0.935456885 CTH1 the form Cx8Cx5Cx3H [where x is a variable amino acid (aa)] YDR152W 0.774441572 0.023621629 -0.320450863 0.361991534 weak similarity to C.elegans hypothetical protein CET26E3 YDR153C 0.112330355 0.461351798 -0.3127629 0.147898065 hypothetical protein YDR154C 0.150409115 0.699002116 0.544554289 0.205802688 questionable ORF YDR156W 1.3153461 0.13317978 0.811024436 0.012042792 RPA14 RNA polymerase I subunit A14 YDR157W 1.007524691 0.20257452 0.655445691 0.027422142 questionable ORF YDR158W 1.19084433 0.172631858 0.073971841 0.529115765 HOM2 aspartic beta semi-aldehyde dehydrogenase YDR159W 0.378374172 0.274138184 -0.331873737 0.145122921 SAC3 Leucine permease transcriptional regulator YDR160W -0.36663571 0.044051351 -0.201567224 0.0084845 SSY1 regulator of transporters YDR161W 0.689022539 0.021646055 -0.221977019 0.052875928 TCI1 interacts with PP2C YDR162C 0.269710168 0.242356048 -0.450901081 0.029741464 NBP2 interacts with Nap1, which is involved in histone assembly YDR163W -0.02634277 0.842859936 -0.492280766 0.045536771 weak similarity to S.pombe hypothetical protein YDR164C -0.4267988 0.13441724 -0.122895459 0.266175976 SEC1 (putative) SNARE docking complex subunit YDR165W 0.831941628 0.105674061 -0.240362626 0.236332236 weak similarity to hypothetical C.elegans protein YDR166C 0.109540847 0.638297289 0.04057337 0.810919393 SEC5 107 kDa component of the Exocyst complex ; required for exocytosis. YDR167W 0.080900411 0.511271694 -0.287421667 0.081915838 TAF25 TFIID subunit YDR168W -0.17026505 0.437790132 -0.710858837 0.032265286 CDC37 (putative) chaperone, involved in spindle pole body duplication and passage through START YDR169C -0.36041468 0.213578914 0.185839648 0.047786559 STB3 Sin3 binding protein YDR170C -0.32509896 0.117714678 0.024512258 0.767550811 SEC7 Guanine nucleotide exchange protein for ARF YDR171W -1.38992838 0.00932314 0.109623405 0.420883484 HSP42 heat shock protein similar to HSP26, involved in cytoskeleton assembly YDR172W 0.468661458 0.071219066 0.129687874 0.346522867 SUP35 translation termination factor eRF3 YDR173C -0.49412067 0.027865871 -0.261396756 0.147287006 ARG82 dual-specificity inositol 1,4,5-trisphosphate 6-kinase /inositol 1,4,5,6-tetrakisphosphate 3-kinase (IP3 6- /IP4 3-kinase) YDR174W -0.18212249 0.04969651 -0.301213645 0.088056575 HMO1 35 kDa protein belonging to the high mobility group (HMG) fanily of proteins YDR175C 0.364195882 0.310632245 -0.371693263 0.095241564 RSM24 protein of the small subunit of the mitochondrial ribosome transcription factor ; genetic and mutant analyses suggest that Ngg1p (Ada3p) is part of two transcriptional adaptor /HAT (histone YDR176W 0.683706011 0.103999825 -0.598928385 0.04997065 NGG1 acetyltransferase complexes, the 0.8 MD ADA complex and the 1.8 MD SAGA complex YDR177W 0.093652454 0.459345786 -0.269911319 0.102213898 UBC1 ubiquitin-conjugating enzyme YDR178W -0.9198194 0.011374168 0.818076826 0.119593387 SDH4 succinate dehydrogenase membrane anchor subunit YDR179C -0.338389 0.20218249 -0.781298061 0.00751141 hypothetical protein YDR179W-A 0.41078482 0.296013242 -0.159005538 0.028646094 hypothetical protein YDR180W 0.479892714 0.243994524 0.0958822 0.354139728 SCC2 Sister chromatid cohesion protein YDR181C -0.42654957 0.041263092 -0.972099434 0.032113731 SAS4 involved in silencing at telomeres, HML, and HMR YDR182W -0.19576155 0.109494391 -0.073197487 0.018663059 CDC1 involved in ion homeostasis YDR183W 0.183151948 0.395113722 -0.648403779 0.03220585 PLP1 Phosducin-Like Protein YDR184C 1.514422499 0.045833914 -0.213404863 0.34860958 ATC1 nuclear protein that interacts with Aip3 YDR185C 0.534086934 0.192845617 0.301053581 0.008101073 strong similarity to Msf1p YDR186C -0.25312804 0.002477664 -0.351093602 0.004445 hypothetical protein YDR187C 0.084761184 0.549220896 -0.002172045 0.989658997 questionable ORF YDR188W -0.00836729 0.95636657 -0.274295123 0.023865545 CCT6 component of cytoplasmic chaperonin complex YDR189W 0.364242732 0.07936368 -0.074752582 0.485833831 SLY1 SNARE docking complex subunit YDR190C 0.584539368 0.031631154 -0.274323636 0.06723679 RVB1 RUVB-like protein YDR191W 0.184328022 0.233489754 0.160522116 0.031724476 HST4 similar to nuclear lamins, involved in telomeric silencing YDR192C 0.184760319 0.47384085 0.129061898 0.02976581 NUP42 42-kD protein associated with nuclear pore complexes ; Nup42p is structurally related to the FG-nucleoporin family of pore proteins YDR193W 0.053925478 0.863112919 0.45412797 0.003831553 questionable ORF YDR194C 0.551315318 0.065672817 -0.99497623 0.001858219 MSS116 Mitochondrial DEAD box RNA helicase YDR195W 0.284667189 0.017240321 -0.085627234 0.400039845 REF2 RNA-binding protein, involved in mRNA processing YDR196C -0.46681995 0.010061187 -0.244271854 0.34264763 similarity to C.elegans hypothetical protein T05G5.5 YDR197W 0.48782613 0.076300948 -0.174542872 0.363208276 CBS2 cytochrome b translational activator YDR198C 0.378227801 0.027630418 -0.554916473 0.027999016 hypothetical protein YDR199W -0.18652689 0.384536148 0.180006991 0.455896264 questionable ORF YDR200C -0.08581319 0.622794745 -0.360476417 0.168755828 similarity to hypothetical protein YLR238w YDR201W 0.398434166 0.391370519 -0.35157571 0.087329291 SPC19 component of spindle pole YDR202C -0.70858516 0.012726916 -0.184353107 0.517385368 RAV2 Regulator of (H+)-ATPase in Vacuolar membrane YDR203W -0.7242513 0.032510066 0.013005458 0.941996197 questionable ORF YDR204W -1.04969527 0.00219414 0.021677225 0.766218858 COQ4 involved in ubiquinone biosynthesis YDR205W -0.62707918 0.023273356 0.536148824 0.11393379 MSC2 similarity to A.eutrophus cation efflux system membrane protein czcD, rat zinc transport protein ZnT-1 and Cot1p YDR206W 0.252225772 0.06545982 -0.211591993 0.388502823 EBS1 similar to Est1, which is a putative component of telomerase YDR207C 0.051111126 0.811339856 0.10611886 0.454731195 UME6 Ume6p is a C6 zinc finger URS1-binding protein. YDR208W -0.01853684 0.910556959 0.036098564 0.478206746 MSS4 Phosphatidylinositol 4-phosphate kinase YDR209C 0.391374526 0.084674312 -0.356586971 0.205906206 questionable ORF YDR210W 0.698903896 0.041686858 -0.332239046 0.063542978 strong similarity to hypothetical protein YBR016w YDR210W-C 0.882189219 0.040337792 0.428006112 0.038873466 TyA gag protein. Gag processing produces capsid proteins. YDR211W 0.343048215 0.258745689 -0.557836415 0.00206436 GCD6 Translation initiation factor eIF-2B epsilon subunit YDR212W -0.0964064 0.410909936 0.015192673 0.885295864 TCP1 chaperonin subunit alpha YDR213W 0.751034769 0.172301224 -0.150164598 0.179573676 UPC2 zinc finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type YDR214W -0.70854059 0.001381083 -0.063505445 0.879967173 similarity to hypothetical protein YNL281w YDR215C -0.00850754 0.979126562 1.309139425 0.207865526 hypothetical protein YDR216W -1.44966312 0.00547645 0.17495673 0.412638103 ADR1 positive transcriptional regulator of ADH2 and peroxisomal protein genes YDR217C 0.059397125 0.589834054 -0.74267718 0.070309531 RAD9 cell cycle arrest protein YDR218C -0.325545 0.205048471 0.37834678 0.293047485 SPR28 septin-related protein expressed during sporulation YDR219C -0.80676903 0.026249692 -0.512237161 0.091153567 hypothetical protein YDR220C -0.53971804 0.02535959 0.292217238 0.348141776 questionable ORF YDR221W -0.04006467 0.840321735 0.147797673 0.268719962 weak similarity to the beta subunit of an ER luminal alpha-glucosidase from mouse YDR222W 0.053160881 0.87876346 0.171868272 0.129765016 strong similarity to hypothetical protein YLR225c YDR223W -0.46073488 0.43338354 0.353904593 0.159734333 similarity to Ifh1p YDR224C 0.536037205 0.141297826 0.256358027 0.149279852 HTB1 Histone H2B (HTB1 and HTB2 code for nearly identical proteins) YDR225W 1.375774247 0.202825605 0.184117926 0.251631696 HTA1 Histone H2A (HTA1 and HTA2 code for nearly identical proteins) YDR226W 1.23819216 0.331893837 0.186896007 0.251224095 ADK1 adenylate kinase YDR227W -0.32363599 0.357080791 -0.347779754 0.145214075 SIR4 regulator of silencing at HML, HMR, and telomeres YDR228C 0.257016534 0.115702536 -0.128277841 0.241369861 PCF11 Component of pre-mRNA cleavage and polyadenylation factor I YDR229W 0.08847097 0.571329776 -0.092324736 0.606678068 hypothetical protein YDR230W -0.49956786 0.105369828 0.339417324 0.506439288 questionable ORF YDR231C -0.98607883 0.017232467 0.114100044 0.618973549 COX20 protein required for maturation and assembly of cytochrome oxidase subunit II YDR232W 0.132023373 0.809325263 0.645044092 0.074156982 HEM1 5-aminolevulinate synthase YDR233C 0.748019233 0.070131039 0.818308015 0.040495499 similarity to hypothetical protein YDL204w YDR234W 0.731367269 0.201243178 -0.117591505 0.314127587 LYS4 homoaconitase YDR236C -1.03022089 0.000134445 0.219186708 0.10094327 FMN1 Riboflavin kinase YDR237W 0.416781114 0.182772546 0.547327986 0.001093921 MRPL7 Mitochondrial ribosomal protein MRPL7 (YmL7) YDR241W -0.15063944 0.830174573 0.040882038 0.216248826 questionable ORF YDR242W 0.565742501 0.379051947 -0.195785865 0.130202402 AMD2 putative amidase YDR243C 0.87894121 0.041508824 0.47021407 0.016251224 PRP28 RNA helicase YDR244W 0.361207609 0.357311766 -0.22424617 0.291128439 PEX5 69-kDa protein containing tetratricopeptide repeat (TPR) YDR245W 0.476929704 0.195282774 -0.389771342 0.061886094 MNN10 galactosyltransferase YDR246W -0.27673241 0.037569008 0.09335625 0.225863989 TRS23 TRAPP subunit of 23 kDa YDR247W -2.2195651 0.001297132 0.519009704 0.074589499 strong similarity to Sks1p YDR249C 0.49954876 0.218357692 0.093269378 0.042174535 weak similarity to cytochrome b YDR250C 0.154553214 0.73884961 0.098472868 0.422649731 hypothetical protein YDR251W -0.0074713 0.979865469 -0.158048216 0.107041615 PAM1 multicopy suppressor of protein phosphatase 2A YDR252W 0.209149716 0.324685982 -0.179917496 0.220846137 BTT1 negative regulator of RNA polymerase II YDR253C 0.144438455 0.784900697 0.23047807 0.16372162 MET32 zinc finger DNA binding factor, transcriptional regulator of sulfur amino acid metabolism, highly homologous to Met31p YDR254W -0.46543508 0.007148916 0.044163913 0.718873718 CHL4 chromosome segregation protein YDR255C -0.55527888 0.064055006 -0.077098865 0.059263055 weak similarity to hypothetical S.pombe hypothetical protein SPBC29A3 YDR256C -0.04740211 0.913361403 0.183705575 0.288703986 CTA1 catalase A YDR257C 0.451750618 0.112801427 -0.572866197 0.09536622 RMS1 (putative) transcriptional regulator YDR258C -1.38847847 0.004017737 -0.563415932 0.006690059 HSP78 Mitochondrial heat shock protein 78 kDa YDR259C -0.01612282 0.902499882 0.0944237 0.475097365 YAP6 basic leucine zipper transcription factor YDR260C 0.039315484 0.819934061 -0.061991021 0.377638839 SWM1 Spore Wall Maturation 1 YDR261C 1.117137287 0.13892855 0.506723694 0.093109816 EXG2 Exo-1,3-b-glucanase YDR262W -0.75660309 0.135289904 0.084541497 0.209037192 hypothetical protein YDR263C 0.834559779 0.035583013 0.340294284 0.278617548 DIN7 involved in DNA repair YDR264C 0.408084101 0.34816499 0.02087241 0.647954286 AKR1 Ankyrin repeat-containing protein YDR265W -0.03503159 0.89387485 -0.293686505 0.055903909 PEX10 C3HC4 zinc-binding integral peroxisomal membrane protein YDR266C 0.571158706 0.044005027 0.037847913 0.795088308 similarity to hypothetical C.elegans protein YDR267C 0.473846332 0.095887121 -0.007949727 0.848112462 weak similarity to human TAFII100 and other WD-40 repeat containing proteins YDR268W 0.628361651 0.22014172 -0.258907107 0.050999344 MSW1 mitochondrial tryptophanyl-tRNA synthetase YDR269C -0.37769852 0.366155496 -0.302964253 0.208559261 questionable ORF YDR270W -0.33118429 0.379535629 0.147804978 0.398331888 CCC2 Cu(2+)-transporting ATPase YDR271C -0.11986647 0.609725116 0.725267251 0.018915416 questionable ORF YDR272W -0.92784608 0.003276525 -0.32680297 0.032455709 GLO2 Cytoplasmic glyoxylase-II YDR273W -1.09202467 0.005839006 -0.156178139 0.410817823 weak similarity to YOR042w YDR274C 0.092589039 0.101726394 0.008934084 0.938715117 hypothetical protein YDR275W -1.07341788 0.003082148 -0.625282059 0.023715319 weak similarity to YOR042w YDR276C 0.252065661 0.448809343 0.792064688 0.122316766 PMP3 hypothetical transmembrane protein YDR277C -0.46989416 0.360348018 0.068364987 0.54501897 MTH1 Protein is 61 % identical to Msn3p YDR278C 0.225176024 0.658317249 1.294144031 0.094683403 hypothetical protein YDR279W 0.211505897 0.093712523 -0.290722625 0.114960707 hypothetical protein YDR280W 0.940828302 0.146812506 -0.39084996 0.132024068 RRP45 Putative 3'->5' exoribonuclease ; component of exosome complex of 3'->5' exonucleases YDR281C -3.09108484 1.65893E-05 0.426485093 0.56208095 PHM6 phosphate metabolism ; transcription is regulated by PHO system YDR282C -0.79988798 0.016591341 -0.472140367 0.000400624 similarity to hypothetical protein YDL001w, YFR048w and S.pombe hypothetical protein SPAC12G12.14 YDR283C 0.200148815 0.342108865 0.442649677 0.310735676 GCN2 eukaryotic initiation factor 2 alpha (eIF2-alpha) kinase YDR284C -0.53746221 0.13244537 0.389522796 0.246834229 DPP1 Diacylglycerol Pyrophosphate Phosphatase YDR285W -0.07958782 0.867106119 -0.240984375 0.426064413 ZIP1 synaptonemal complex protein YDR286C 0.031068848 0.782636815 -0.319559138 0.039433312 hypothetical protein YDR287W -0.4256767 0.084371208 -0.017302743 0.823927363 similarity to inositolmonophosphatases YDR288W -1.08740667 0.002644606 -0.633389513 0.097226878 hypothetical protein YDR289C -0.14625261 0.497268474 -0.872011891 0.00916851 RTT103 regulator of Ty1 Transposition YDR290W 0.109880177 0.822957476 0.425122993 0.35004386 questionable ORF YDR291W 0.077189235 0.378369157 -0.402537322 0.027916362 similarity to B.subtilis helicases YDR292C 0.367806884 0.08155011 -0.231562229 0.143617155 SRP101 signal recognition particle receptor - alpha subunit YDR293C -0.60196532 0.035784653 0.301959061 0.221714173 SSD1 putative protein phosphatase//involved in the tolerance to high concentration of Ca2+ YDR294C -0.3918463 0.031442325 0.057996929 0.665177156 DPL1 dihydrosphingosine phosphate lyase (also known as sphingosine phosphate lyase) YDR295C 0.203225925 0.441538848 -0.399218253 0.027928247 PLO2 Ploidy-related YDR296W 0.643290739 0.115802202 -0.144796834 0.281708489 MHR1 Involved in mitochondrial homologous DNA recombination YDR297W 0.60940165 0.487077662 0.592441019 0.02104678 SUR2 Syringomycin response protein 2 YDR298C -1.02440741 0.015304495 0.190312258 0.313488547 ATP5 ATP synthase subunit 5 ; oligomycin sensitivity-conferring protein YDR299W 1.039613703 0.072190318 -0.755654381 0.06795584 BFR2 involved in secretion YDR300C 0.823041186 0.195090145 -0.220847658 0.010302868 PRO1 gamma-glutamyl kinase YDR302W 0.128073106 0.594956584 0.162193616 0.002055641 GPI11 GPI-phosphoethanolamine transferase Gpi7p subunit YDR303C -0.26996637 0.110533266 0.012418052 0.855231473 RSC3 Zinc cluster protein YDR304C 0.151140212 0.101124336 0.505478174 0.026007632 CYP5 Cyclophilin D, Peptidyl-prolyl cis-trans isomerase D YDR305C -0.25634087 0.016922825 -0.162409736 0.21274682 HNT2 member of the histidine triad family YDR306C -0.97162481 0.009530572 -0.327650608 0.128722909 weak similarity to S.pombe hypothetical protein SPAC6F6 YDR307W -0.38685829 0.084945542 0.344183224 0.160605162 similarity to Pmt1p, Pmt2p, Pmt3p and Pmt5p YDR308C 0.49738241 0.158787129 -0.396866868 0.173159567 SRB7 RNA polymerase II holoenzyme component YDR309C 1.309271811 0.162511195 0.405386498 0.082988552 GIC2 Cdc42 binding protein, involved in bud emergence YDR310C -0.00509228 0.990256215 -0.028463666 0.741946352 SUM1 nuclear protein involved in silencing YDR311W 0.202367066 0.519868681 -0.540613327 0.083301012 TFB1 Component of transcription initiation factor IIb, 75 kDa subunit YDR312W 0.917173747 0.021081828 -0.704816627 0.066751245 SSF2 possibly involved in mating YDR313C -0.72671418 0.036108983 -0.068263192 0.337158487 PIB1 phosphatidylinositol(3)-phosphate binding protein YDR314C -0.73594857 0.003977244 -0.480859554 0.008034617 weak similarity to hypothetical S.pombe protein YDR315C 0.090200988 0.788192923 -0.369531309 0.080349992 IPK1 inositol 1,3,4,5,6-pentakisphosphate 2-kinase (IP5 2-kinase) YDR316W 0.635430718 0.05554938 -0.681186553 0.054737873 putative methyltransferase YDR316W-A 1.144766118 0.19349643 0.382734547 0.008266509 TyA gag protein. Gag processing produces capsid proteins. YDR317W 0.340156275 0.381328777 -0.09974564 0.01309692 hypothetical protein YDR318W 0.323630365 0.223663522 -0.136689587 0.264594185 MCM21 involved in minichromosome maintenance YDR319C -0.10183668 0.650294345 0.080801776 0.523795714 hypothetical protein YDR320C -0.30130955 0.576404864 -0.02836439 0.696306343 SWA2 Auxilin-like protein YDR321W 0.443949079 0.343356747 0.051334265 0.575697838 ASP1 Asparaginase I, intracellular isozyme YDR322C-A -0.90690127 0.004677359 -0.015235786 0.884402447 TIM11 subunit e of mitochondrial F1F0-ATPase YDR322W 0.624212866 0.244572423 -0.123886033 0.214790344 MRPL35 Mitochondrial ribosomal protein MRPL35 (YmL35) YDR323C -0.70640484 0.0108053 -0.239110713 0.171379058 PEP7 cytosolic and peripheral membrane protein with three zinc fingers ; cysteine rich regions of amino acids are essential for function YDR324C 1.296562731 0.04988691 -0.589718721 0.043538662 weak similarity to beta transducin from S. pombe and other WD-40 repeat containing proteins YDR325W -0.15777521 0.238748656 -0.586957787 0.122742879 YCG1 Yeast Condensin G YDR326C 0.776967535 0.021254445 0.387259298 0.134077021 strong similarity to YHR080c, similarity to YFL042c and YLR072w YDR327W 0.032050852 0.662294559 0.234813727 0.284606095 questionable ORF Skp1p encodes Cbf3d, a 29 Kd kinetochore protein subunit of CBF3 -- a complex which binds to the CDE III element of centromeres. Skp1p is YDR328C -0.13001779 0.331861724 0.083010175 0.456339183 SKP1 also a subunit of the SculCdc4 (also termed SCFCdc4p) complex. SculCdc4 transfers ubiquitin to phosphorylated Sic1p an YDR329C -0.44546159 0.087930718 -0.081796216 0.009829847 PEX3 48-kDa peroxisomal integral membrane protein YDR330W -0.63515583 0.023467532 -0.32805164 0.226711233 similarity to hypothetical S. pombe protein YDR331W 0.441427492 0.104994146 0.262280486 0.093792673 GPI8 (putative) transamidase involved in GPI anchor attachment YDR332W -0.158491 0.486517233 -0.443353869 0.03708463 similarity to E.coli hypothetical protein and weak similarity to RNA helicase MSS116 / YDR194c YDR333C 0.354558934 0.06906153 -0.45236397 0.058420741 similarity to hypothetical S. pombe protein YDR334W 1.180038031 0.020905523 -0.788724905 0.037120081 SWR1 DEAH-box protein, putative RNA helicase YDR335W -0.38339906 0.001947273 -0.066849526 0.535267259 MSN5 member of major facilitator superfamily, involved in pheromone response YDR336W -0.67073971 0.00668861 -0.384168538 0.036538568 weak similarity to B.subtilis hypothetical protein X YDR337W -0.02323003 0.882532974 -0.700979876 0.036993328 MRPS28 Mitochondrial ribosomal protein MRPS28 (E. coli S15) YDR338C -0.27860148 0.336050746 0.297020938 0.161556481 similarity to Erc1p YDR339C 0.778740257 0.052827563 -0.219557888 0.380283014 weak similarity to hypothetical protein YOR004w YDR340W 0.124890544 0.456853875 -0.039096633 0.763898966 questionable ORF YDR341C 0.807918061 0.069529398 -0.234887035 0.024463296 arginyl-tRNA synthetase, cytosolic YDR342C -0.98566979 0.131106634 0.624470061 0.132175048 HXT7 Hexose transporter YDR343C -0.90682682 0.168627204 0.474054126 0.143027206 HXT6 Hexose transporter YDR344C 0.536320684 0.355207017 0.81411449 0.089154329 hypothetical protein YDR345C 1.279014581 0.287016313 0.664694541 0.12390185 HXT3 Low-affinity glucose transporter YDR346C -0.01617388 0.944132722 -0.731270266 0.029709168 similarity to hypothetical S.pombe protein YDR347W 0.329247591 0.193969833 -0.066495992 0.590824861 MRP1 37 kDa mitochondrial ribosomal protein YDR348C 0.583405594 0.002966238 0.015082048 0.840339226 similarity to hypothetical protein YHR097c YDR349C 0.62369267 0.151051385 0.434266437 0.084043245 YPS7 GPI-anchored aspartic protease YDR350C -0.18347224 0.364505363 -0.214456194 0.027199199 TCM10 protein of unknown function YDR351W 0.820881295 0.113364131 -0.125761382 0.109860118 SBE2 involved in bud growth YDR352W -0.3811665 0.114259784 0.154680578 0.403931812 weak similarity to hypothetical proteins YOL092w, YBR147w and YMR010w YDR353W 0.792031628 0.33143244 0.232832587 0.314187473 TRR1 Thioredoxin reductase YDR354W 0.481821746 0.145145932 0.224272433 0.135230668 TRP4 anthranilate phosphoribosyl transferase YDR355C -0.106572 0.818878186 4.368111476 0.417154919 questionable ORF YDR356W 0.035600774 0.878504969 -0.702036029 0.060863921 NUF1 component of the spindle pole body that interacts with Spc42p, calmodulin, and a 35 kDa protein YDR357C -0.56722841 0.054611691 -0.405201685 0.001724743 hypothetical protein YDR358W -1.44976349 0.001770383 -0.309080538 0.088995647 GGA1 Arf-binding protein YDR360W 0.595875206 0.41037125 0.575655747 0.125326733 questionable ORF YDR361C 0.838337599 0.019311934 -0.444068153 0.105619865 hypothetical protein YDR362C -0.38431442 0.016360869 -0.335717738 0.015131379 TFC6 91 kDa tau91 subunit of transcription factor IIIC (TFIIIC) YDR363W -0.23386793 0.532168582 -0.618752292 0.058498904 ESC2 establishes silent chromatin YDR363W-A 0.545356774 0.060734551 -0.496686513 0.110228944 SEM1 unknown function, similar to S. pombe Dss1 YDR364C 0.011696618 0.878878791 -0.5012085 0.044683432 CDC40 Member of the beta transducin family YDR365C 0.921985996 0.146450281 -0.921463761 0.047930083 weak similarity to Streptococcus M protein YDR365W-A 0.915508242 0.010618658 0.442576964 0.021953487 TyA gag protein. Gag processing produces capsid proteins. YDR366C 0.326795808 0.379091497 0.070929539 0.437582139 similarity to YOL106w and YER181c YDR367W 0.147462381 0.731313317 0.159442615 0.08198696 hypothetical protein YDR368W -1.51818968 0.000864158 0.321163473 0.263063682 YPR1 similar to aldo-keto reductase YDR369C -0.5707983 0.029069973 -0.400264327 0.094436285 XRS2 DNA repair protein YDR370C 0.801674746 0.046340508 -0.262081672 0.231858658 hypothetical protein YDR371W 0.499616491 0.258224382 -0.325720196 0.24552824 similarity to chitinases YDR372C 0.111793902 0.699508919 -0.41233227 0.019002772 similarity to hypothetical S. pombe protein YDR373W 0.602253475 0.029969337 -0.141117709 0.016049025 FRQ1 regulator of phosphatidylinositol-4-OH kinase protein YDR374C 0.392982154 0.522875711 0.417977968 0.236249136 similarity to hypothetical A. thaliana protein BAC F21M12 YDR375C 0.686481635 0.183395379 -0.168728017 0.086368684 BCS1 Mitochondrial ATPase (AAA family) YDR376W 0.058579686 0.834083171 -0.386213369 0.004074666 ARH1 adrenodoxin oxidoreductase homolog YDR377W -0.82027602 0.001781848 -0.1793832 0.438550319 ATP17 ATP synthase subunit f YDR378C 0.378922289 0.069342427 0.084070678 0.184026588 LSM6 Sm-like protein YDR379W 0.268733771 0.591350091 -0.176475274 0.148868542 RGA2 Contains a Rho-GAP domain and two LIM domains. Has strong similarity to Rga1p. Has some similarity to all known Rho-GAPs. YDR380W -1.22152817 0.0363281 0.509793696 0.138236987 similarity to Pdc6p, Thi3p and to pyruvate decarboxylases YDR381W 0.529996932 0.324290354 0.025197995 0.781747868 YRA1 Nuclear RNA-binding RNA annealing protein YDR382W 2.220277424 0.066689938 0.428438433 0.003750935 RPP2B Ribosomal protein P2B (YP2beta) (L45) YDR383C 0.485441759 0.153799749 -0.205860487 0.135544998 weak similarity to S.pombe paramyosin YDR384C 1.43602624 0.151594784 0.610719551 0.021982557 strong similarity to Y.lipolytica GPR1 gene YDR385W 1.308443985 0.173032647 0.26345481 0.425144907 EFT2 translation elongation factor 2 (EF-2) YDR386W -0.33183069 0.089507768 -0.714809184 0.024298515 MUS81 involved in DNA repair, interacts with Rad54 YDR387C -0.16119172 0.556278671 0.133769676 0.378509624 similarity to Itr1p and Itr2p and E.coli araE YDR388W -0.49068859 0.122429304 0.153937595 0.160990184 RVS167 (putative) cytoskeletal protein YDR389W 0.34836191 0.180599178 0.402057369 0.071349243 SAC7 GTPase activating protein (GAP) for RHO1 YDR390C 0.386032067 0.077734581 -0.110015022 0.495536765 UBA2 similar to ubiquitin activating enzyme (E1) YDR391C 0.11065802 0.839098704 -0.012211618 0.713845493 transcriptional activator//general transcriptional adaptor or co-activator YDR392W -0.28487372 0.090996821 -0.584519519 0.010763734 SPT3 transcription factor, member of the histone acetyltransferase SAGA complex YDR393W -1.19063802 0.001807232 0.823266158 0.061393742 SHE9 similar to Arabidopsis Cip1, lethal when overexpressed YDR394W 0.133149596 0.663960597 0.019199598 0.384322886 RPT3 ATPase (AAA family) component of the 26S proteasome complex Sxm1p shares similarity with Cse1p homologs including Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1 ; YDR395W 1.131609452 0.058341845 0.211052181 0.060565627 SXM1 Sxm1p also shares homology with the karyopherin, Kap95p ; Sxm1p is primarily a nuclear protein YDR396W 0.367176809 0.328080478 0.070262868 0.622672577 hypothetical protein YDR397C 0.343755804 0.188835565 -0.372481754 0.161741531 NCB2 repressor of class II transcription YDR398W 0.80151525 0.049737942 0.142475735 0.312080085 similarity to human KIAA0007 gene YDR399W 1.163829532 0.096682641 -0.029127361 0.788194658 HPT1 hypoxanthine guanine phosphoribosyltransferase YDR400W -0.06634951 0.808107658 0.151165234 0.295515628 URH1 uridine nucleosidase (uridine ribohydrolase) ; EC 3.2.2.3 YDR401W 0.163633737 0.57072403 0.223095935 0.426995089 questionable ORF YDR402C 0.219066424 0.603983284 -0.10549513 0.347333559 DIT2 Cytochrome P450 56, Dit2p catalyzes oxidation of N-formyl tyrosine to N,N-bisformyl dityrosine in vitro first enzyme in dityrosine synthesis in the outer layer of the spore wall pathway converting L-tyrosine to N-formyl-L-tyrosine, expressed late (10- YDR403W -0.35187998 0.009536199 -0.067972813 0.724489941 DIT1 16 hr) in sporulation YDR404C 0.700787011 0.038132526 0.314224765 0.057113029 RPB7 dissociable subunit of RNA polymerase II YDR405W 0.407869997 0.369789242 0.353183079 0.204100232 MRP20 263-amino acid mitochondrial ribosomal large subunit protein ; similar to L23 family of ribosomal proteins YDR407C 0.099383716 0.431500088 -0.019036441 0.885642482 TRS120 Component of targeting complex (TRAPP) involved in ER to Golgi membrane traffic YDR408C 0.908706344 0.202445621 0.210421228 0.173451021 ADE8 glycinamide ribotide transformylase YDR410C 0.905683825 0.236070062 0.542633146 0.081160598 STE14 farnesyl cysteine-carboxyl methyltransferase YDR411C 0.227379171 0.160110973 0.453362524 0.145694807 weak similarity to Der1p YDR412W 0.200787629 0.257764554 -0.694060937 0.038429862 questionable ORF YDR413C 0.044323259 0.789133565 -0.711652136 0.052076263 weak similarity to NADH dehydrogenase YDR414C 0.126965094 0.460110701 0.074952171 0.401226511 ERD1 involved in rentention of lumenal ER proteins YDR415C 0.236646186 0.508240151 0.211066833 0.163498664 strong similarity to bacterial leucyl aminopeptidase YDR416W 0.191920817 0.148750807 -0.395996953 0.017726727 SYF1 (putative) involved in cell cyle ; similar to Drosophila crooked neck YDR417C 0.109012398 0.705458291 0.105566986 0.049278455 questionable ORF YDR418W 0.718618587 0.036794052 0.039131475 0.493819128 RPL12B Ribosomal protein L12B (L15B) (YL23) YDR421W -0.6918314 0.095278557 -0.333093964 0.023030874 hypothetical protein YDR422C -0.3288677 0.053069588 0.243060843 0.226069715 SIP1 SNF1 protein kinase substrate YDR423C -0.32500139 0.161244822 0.122154395 0.147333682 CAD1 basic leucine zipper transcription factor YDR425W -0.30617011 0.248471638 -0.073626369 0.448723836 similarity to hypothetical protein YDL113c YDR427W 0.171985813 0.622925662 -0.374313538 0.084651338 RPN9 Subunit of the regulatory particle of the proteasome YDR428C -0.3573216 0.133073405 -0.341550531 0.011450049 hypothetical protein YDR429C 0.427038771 0.115919042 -0.748841678 0.033147906 TIF35 translation initiation factor eIF3 subunit YDR430C 0.557950535 0.205643787 -0.60075329 0.070439495 similarity to C.perfringens hypothetical hypA protein YDR431W 0.785073117 0.025177833 -0.129718546 0.433407813 questionable ORF YDR432W 0.377713434 0.495764478 -0.464364017 0.359797418 NPL3 nuclear shuttling protein with an RNA recognition motif YDR433W -0.0691753 0.865331191 -0.127728664 0.476396156 questionable ORF YDR434W -0.08024147 0.672738269 -0.059475483 0.086485818 similarity to S.pombe hypothetical protein YDR435C -0.80263171 0.034532013 -0.214719074 0.028539446 PPM1 carboxy methyl transferase for protein phosphatase 2A catalytic subunit YDR436W -0.31176373 0.466621601 0.439936567 0.179121988 PPZ2 serine-threonine phosphatase Z YDR437W 1.414359174 0.220805257 0.617353891 0.042670291 hypothetical protein YDR438W 3.220277118 0.309583604 0.568503813 0.103735308 strong similarity to hypothetical protein YML018c YDR439W -0.44812343 0.083386822 -0.333787069 0.049815178 LRS4 involved in rDNA silencing YDR440W 0.243719069 0.391652809 -0.453564985 0.020699001 DOT1 involved in meiosis and transcriptional silencing YDR441C 0.649793423 0.012137397 0.988321229 0.12149114 APT2 Adenine Phosphoribosyltransferase YDR442W 0.326767425 0.078852021 0.357901606 0.090503988 questionable ORF YDR443C -0.33714205 0.090916917 0.312589841 0.01964241 SSN2 transcription factor YDR444W 0.078000728 0.696797352 -0.339611151 0.040905102 lipase family protein containing serine active site YDR445C 0.05001446 0.845455469 0.403478098 0.018694971 questionable ORF YDR446W 0.356962096 0.545918924 -0.537438773 0.317538337 ECM11 (putative) involved in cell wall biogenesis YDR447C 1.055119248 0.089987338 -0.489944811 0.08489435 RPS17B Ribosomal protein S17B (rp51B) YDR448W 0.731821124 0.082515409 0.36585192 0.027264188 ADA2 transcription factor, member of ADA and SAGA, two transcriptional adaptor /HAT (histone acetyltransferase)complexes YDR449C 1.572678231 0.113073448 -0.65300726 0.135022595 hypothetical protein YDR450W 1.329530264 0.047370355 -0.073409286 0.687153255 RPS18A Ribosomal protein S18A YDR451C 0.64006381 0.211871888 0.381901384 0.041503308 strong similarity to Yox1p YDR452W -0.39520633 0.1134875 -0.230495457 0.093323904 PHM5 vacuolar polyphosphatase YDR453C -1.01039156 0.02072384 0.316183279 0.178791675 strong similarity to thiol-specific antioxidant proteins YDR454C 0.085390424 0.819950609 0.117912425 0.500345059 GUK1 guanylate kinase YDR455C 0.078012919 0.70840955 0.892289851 0.081305763 questionable ORF YDR456W -0.0811503 0.810741052 0.546027031 0.139090496 NHX1 Na+ /H+ exchanger YDR458C -0.39583791 0.05285198 -0.77354765 0.043644449 similarity to hypothetical protein YML034w and YML033w YDR459C 0.272717457 0.168395967 0.183703941 0.267191667 weak similarity to YNL326c YDR460W 0.137116239 0.49706668 -0.281656195 0.259832787 TFB3 TFIIH subunit Tfb3 , contains ring finger motif ; similar to mammalian CAK subunit YDR461W 0.107988642 0.835483221 0.641486691 0.206247667 MFA1 a-factor mating pheromone precursor YDR462W 0.690329011 0.167666367 0.190713969 0.217104614 MRPL28 Mitochondrial ribosomal protein MRPL28 (YmL28) YDR463W -0.22932134 0.376865243 0.003894358 0.977072166 STP1 Nuclear-localized protein containing zinc finger motifs YDR464W -0.4858465 0.099067405 -0.471035194 0.123596351 SPP41 negative regulator of prp genes YDR465C 1.269743619 0.012577124 -0.280269761 0.288398924 RMT2 Protein arginine methyltransferase YDR466W -0.1187259 0.330160874 -0.041971095 0.425605434 similarity to ser/thr protein kinase YDR467C 0.437282212 0.004341548 0.126771034 0.01268958 questionable ORF YDR468C 0.258528633 0.276279986 -0.480373122 0.195360173 TLG1 tSNARE that affects a Late Golgi compartment YDR469W 0.556475792 0.32891975 -0.567206696 0.127240107 hypothetical protein YDR470C 0.10599613 0.452434867 0.086002736 0.261479016 similarity to chromosome segregation protein Cse1p YDR471W 1.407346931 0.127932715 0.080286664 0.720570589 RPL27B Ribosomal protein L27B YDR472W 0.468252567 0.035173641 0.35102071 0.059983935 TRS31 Component of targeting complex (TRAPP) involved in ER to Golgi membrane traffic YDR473C -0.14501529 0.101737379 -0.796734521 0.035905134 PRP3 snRNP from U4 /U6 and U5 snRNPs YDR474C -1.1407093 0.025947946 0.097189595 0.574841579 similarity to C-terminal region of YOR019w YDR475C -0.64051052 0.171075436 -0.17928331 0.19340542 hypothetical protein YDR476C 0.424252463 0.29990515 0.722649894 0.061711419 hypothetical protein YDR477W -0.8803078 0.023770665 -0.009458246 0.927983207 SNF1 protein serine /threonine kinase YDR478W 0.443378162 0.204195488 -0.205440771 0.042849832 SNM1 RNase MRP (Mitochondrial RNA Processing) protein component YDR479C -0.38171273 0.212067837 0.04038653 0.637999562 weak similarity to YHR150w YDR480W 0.671051084 0.013578193 0.00856948 0.956587281 DIG2 MAP kinase-associated protein YDR481C -1.99037994 0.000686781 -0.009850281 0.836075207 PHO8 repressible alkaline phosphatase YDR482C 0.702960167 0.154600008 0.108230023 0.206729017 hypothetical protein YDR483W -0.22465382 0.54312052 0.354642104 0.105293477 KRE2 alpha-1,2-mannosyltransferase YDR484W -0.01054578 0.913939587 -0.476497722 0.125854483 SAC2 involved in localization of actin and chitin YDR485C 0.15733072 0.276606244 -0.559699956 0.056382733 similarity to trichohyalin YDR486C -0.08924129 0.417412719 -0.041197733 0.731263246 weak similarity to Snf7p YDR487C 1.241190587 0.208587209 0.410317033 0.060187364 RIB3 3,4-dihydroxy-2-butanone 4-phosphate synthase YDR488C -0.15336153 0.46013114 -0.016980803 0.937758614 PAC11 similar to rat dynein intermediate chain YDR489W 0.921891519 0.052915741 0.315647878 0.040247745 hypothetical protein YDR490C 0.070636664 0.901759143 0.474193278 0.160966541 PKH1 Ser /Thr protein kinase YDR491C -0.20905149 0.447728891 0.187816039 0.47027868 questionable ORF YDR492W 0.491705426 0.396576838 0.411732404 0.243057005 strong similarity to hypothetical protein YOL002c YDR493W 0.862295062 0.003628006 0.111636766 0.073595219 hypothetical protein YDR494W 0.463847109 0.168193919 -0.517510062 0.077217586 hypothetical protein YDR495C 0.025978746 0.865070204 -0.662219592 0.041925096 VPS3 vacuolar protein targeting protein YDR496C 1.500595307 0.082775931 -0.668803591 0.11620286 similarity to hypothetical human and C.elegans proteins YDR497C 1.503238844 0.326090113 0.367207341 0.195456864 ITR1 myo-inositol transporter YDR498C -0.37095569 0.100799671 0.180562466 0.550298297 SEC20 membrane glycoprotein, sorted by HDEL retrieval system YDR499W 0.444270404 0.093109272 -0.272011839 0.139747518 LCD1 cell cycle checkpoint protein YDR500C 0.866460723 0.052853159 0.097665805 0.419301977 RPL37B 60S ribosomal protein L37B (L43) (YL35) YDR501W 0.438229824 0.433029437 -0.03106866 0.601610181 PLM2 PLasmid Maintenance YDR502C 0.7778676 0.472161761 -0.128186071 0.135540786 SAM2 S-adenosylmethionine synthetase YDR503C -0.2329969 0.404714877 0.019556247 0.904029927 LPP1 Lipid phosphate phosphatase YDR504C -0.53148042 0.004292095 0.383036808 0.299934941 similarity to hypothetical T.brucei protein YDR505C -0.60910221 0.073575251 0.043434982 0.246013865 PSP1 high-copy suppressor of cdc17 DNA polymerase alpha mutations YDR506C -0.85572483 0.023926734 5.85044E-05 0.999528502 similarity to FET3, YFL041w and F.floriforme diphenol oxidase YDR507C 0.74856798 0.095197621 -0.040433591 0.789753296 GIN4 putative serine /threonine kinase YDR508C 0.725864745 0.038039857 0.216256055 0.031641512 GNP1 high-affinity glutamine permease YDR510W 0.709317217 0.041900883 0.165134377 0.456383289 SMT3 ubiquitin-like protein YDR511W 0.088543555 0.528529009 0.459097453 0.11998256 weak similarity to C. elegans protein F25H9.7 and to the human complement 3 precursor YDR512C -0.10016964 0.363968696 0.451674801 0.026372911 questionable ORF YDR513W -1.0791281 0.00255906 0.362849642 0.169457024 TTR1 Glutaredoxin (thioltransferase) (glutathione reductase) YDR514C 1.014838693 0.001830504 -0.330171546 0.120865308 strong similarity to hypothetical protein YCL036w YDR515W 0.60878404 0.098321923 -0.670410763 0.107214846 SLF1 RNA binding protein with La motif YDR516C -0.70646572 0.175719589 0.169365307 0.572838255 strong similarity to glucokinase YDR517W -0.85217115 0.005233038 0.097125926 0.785518675 GRH1 Yeast homologue of mammalian GRASP proteins, also localised to the Golgi apparatus. YDR518W -0.04192631 0.899156866 0.324688698 0.055299611 EUG1 Protein disulfide isomerase homolog YDR519W 0.387803425 0.47144229 0.255039565 0.132218247 FKB2 FKBP (FK506 binding protein) 13 ; peptidylprolyl cis-trans isomerase activity YDR520C 0.273002169 0.361623287 -0.106490365 0.233739684 weak similarity to transcription factors of the zinc finger class YDR521W 0.052428752 0.85998739 -0.015364 0.776403642 questionable ORF YDR522C -0.35264905 0.412209649 0.213158051 0.207712266 SPS2 involved in meiosis YDR523C -0.40579537 0.135973796 -0.266421109 0.049780018 SPS1 serine /threonine kinase homologous to Ste20p ; expressed in middle /late meiosis YDR524C 0.421821236 0.004517613 -0.005170742 0.921934563 AGE1 ARF GAP with effector function(s) YDR525W-A -0.05322003 0.77694401 1.366787888 0.081456285 identified by SAGE YDR526C 0.564034417 0.048789361 -0.202204038 0.483773555 questionable ORF YDR527W 0.819774645 0.040265077 -0.510715905 0.127999076 weak similarity to Plasmodium yoelii rhoptry protein YDR528W 0.145063816 0.656584383 -0.065891973 0.510619887 HLR1 Homologous to LRE1 ; antagonistic to PKA YDR529C -1.21816803 0.000415906 0.114455614 0.160800205 QCR7 ubiquinol-cytochrome c oxidoreductase subunit 7 (14 kDa) YDR530C -0.86633203 0.003829176 0.127038549 0.278623745 APA2 5',5'''-P-1,P-4-tetraphosphate phosphorylase II YDR531W 0.298274719 0.123707303 -0.36917609 0.026302615 similarity to hypothetical A. thaliana and C. elegans proteins YDR532C -0.21502178 0.128316543 -0.931480214 0.023468297 weak similarity Plasmodium repeat organellar protein YDR533C -1.40739449 0.027969868 0.041842272 0.812120196 strong similarity to hypothetical proteins YPL280w, YOR391c and YMR322c YDR534C -0.51341322 0.380127767 0.536777168 0.300353236 similarity to YOR383c,Sta1p and pig mucin YDR535C -0.26000857 0.559576667 -0.003325839 0.991810693 hypothetical protein YDR536W -0.23694247 0.640193399 0.105061316 0.354270602 STL1 sugar transporter-like protein YDR537C -0.20821396 0.216222598 0.215197438 0.379516311 questionable ORF YDR538W -0.15442208 0.339520414 0.088028108 0.3134879 PAD1 Phenylacrylic acid decarboxylase YDR539W -0.30521193 0.198449013 0.034452515 0.762023926 similarity to E.coli hypothetical 55.3 kDa protein in rfah-rfe intergenic region YDR540C 0.123253821 0.791617134 -0.309043239 0.081972816 hypothetical protein YDR541C 0.332612161 0.33524877 0.11774126 0.149216587 similarity to dihydroflavonol-4-reductases YDR542W 0.160225095 0.449910795 0.537975105 0.216087899 strong similarity to subtelomeric encoded proteins YDR543C 0.200700763 0.578094255 0.442827629 0.221753251 strong similarity to subtelomeric encoded proteins YDR544C -0.10229422 0.866371184 0.499674866 0.082319594 strong similarity to subtelomeric encoded proteins YDR545W -1.03543746 0.020183012 0.600980893 0.11044168 YRF1-1 Y'-helicase protein 1 YEL001C 1.10257407 0.166641125 0.486664889 0.053776311 hypothetical protein YEL002C 0.09139695 0.816980657 0.367100705 0.142196038 WBP1 oligosaccharyl transferase glycoprotein complex, beta subunit YEL003W 0.033995744 0.91557484 -0.934401915 0.005423721 GIM4 bovine prefoldin subunit 2 homolog (putative) YEL004W 0.456556507 0.254482734 0.067777252 0.181333424 YEA4 similar to Gog5, which is involved in vanadate resistance YEL005C -0.50621267 0.04712766 -0.097860296 0.257733978 VAB2 Vac8p binding protein of 31 kDa YEL006W -0.48193397 0.238856357 -0.336526258 0.060951514 similarity to peroxisomal membrane and mitochondrial carrier proteins YEL008W -0.00517178 0.974878143 0.660434159 9.25E-05 hypothetical protein YEL009C 1.290502612 0.148353071 0.15607677 0.09625498 GCN4 transcriptional activator of amino acid biosynthetic genes YEL010W 0.291551501 0.696653662 0.00476955 0.966678226 hypothetical protein YEL011W -2.49925762 0.00221088 0.298688628 0.351810097 GLC3 1,4-glucan-6-(1,4-glucano)-transferase YEL012W -1.57988663 0.006059706 -0.578477883 0.00696074 UBC8 ubiquitin-conjugating enzyme ; ubiquitin-protein ligase YEL013W -0.2972505 0.037025318 -0.280119285 0.052080505 VAC8 An armadillo repeat-containing protein localized on the vacuolar membrane YEL014C 0.337278941 0.395898678 0.086926635 0.397122206 hypothetical protein YEL015W 0.696610678 0.032507953 -0.582404665 0.073318202 weak similarity to Spa2p YEL016C -0.47177248 0.014843917 0.161139785 0.468612179 similarity to human nucleotide pyrophosphatase YEL017C-A 0.731820516 0.192799861 1.012351431 0.101589885 PMP2 Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p) YEL017W -0.46485983 0.162160571 0.259192515 0.011130458 hypothetical protein YEL018W 0.828087808 0.065537726 -0.351204569 0.113767673 weak similarity to Rad50p YEL019C 0.338297315 0.299284447 0.176956882 0.443655371 MMS21 involved in DNA repair YEL020C -0.86827779 0.015521335 -0.135490194 0.168528786 similarity to O.formigenes oxalyl-CoA decarboxylase YEL020W-A 0.553601956 0.024829396 -0.104340348 0.241410413 TIM9 mitochondrial inner membrane translocase YEL022W 0.231437763 0.478549022 0.0226399 0.446993149 GEA2 ARF GTP /GDP exchange factor YEL023C -0.29614721 0.142933056 -0.127990323 0.224233316 hypothetical protein YEL024W -1.33690609 0.004423295 0.185844227 0.316572509 RIP1 Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex YEL025C -0.00995806 0.957375295 -0.241570363 0.0038768 SRI1 SWI /SNF and RSC interacting protein 1 YEL026W 2.570613313 0.060898561 0.762544715 0.020900433 SNU13 U4 /U6.U5 snRNP component YEL027W 0.788604659 0.044054604 0.914573493 0.080478302 CUP5 vacuolar ATPase V0 domain subunit c (17 kDa) YEL028W 0.530700685 0.239803911 0.293969138 0.050658152 hypothetical protein YEL029C 0.795253956 0.403764732 -0.633751971 0.00223025 similarity to hypothetical protein YNR027w YEL030W -0.75581567 0.140568191 0.194495312 0.323459504 ECM10 similar to Hsp70, involved in cell wall biogenesis YEL031W -0.18803941 0.359111973 0.359063412 0.181983417 SPF1 P-type ATPase YEL033W 0.708141846 0.091912942 0.849938707 0.024812695 weak similarity to Sauroleishmania mitochondrial hypothetical ORF-5 protein YEL034W 0.504269654 0.117599088 0.72425885 0.016418616 HYP2 Translation initiation factor eIF-5A YEL035C 0.342691044 0.507620787 0.450163196 0.132886679 UTR5 protein of unknown function YEL036C 0.594893847 0.022602749 0.317008416 0.059023866 ANP1 subunit of mannosyltransferase complex YEL037C 0.453501065 0.084980312 0.086348871 0.604822376 RAD23 ubiquitin-like protein YEL038W -0.14716836 0.535009193 0.566644399 0.026350052 UTR4 similarity to K.oxytoca enolase-phosphatase E-1 YEL039C -1.04002342 0.018749387 0.227184676 0.043880023 CYC7 iso-2-cytochrome c YEL040W 3.128134933 0.201029382 0.501867212 0.026603408 UTR2 weak similarity to Bacillus 1,3-1,4-beta-glucanase YEL041W -0.90391944 0.026621318 -0.260816936 0.008490218 strong similarity to Utr1p YEL042W 0.527286173 0.240956724 0.348171598 0.001836517 GDA1 Guanosine diphosphatase of Golgi membrane YEL043W 0.015164796 0.962976194 0.335139821 0.036398563 weak similarity to Mad1p YEL044W 0.097459191 0.352332462 0.051738832 0.625780442 hypothetical protein YEL045C 1.143883768 0.19208892 1.344094103 0.020846541 weak similarity to cytochrome c oxidase III of T.brucei kinetoplast YEL046C -0.07792227 0.783790196 0.377726219 0.074570365 GLY1 Threonine Aldolase YEL047C 0.000202793 0.999428217 0.353079196 0.206645219 FRDS1 soluble fumarate reductase, cytoplasmic YEL048C 0.374183795 0.256834127 -0.355024051 0.208630951 hypothetical protein YEL049W -0.23049001 0.674442214 0.796362266 0.050661044 PAU2 similar to members of the seripauperin (PAU) family YEL050C 0.354406938 0.307282316 -0.144303536 0.13369724 RML2 mitochondrial ribosomal protein L2 of the large subunit YEL051W -0.2576987 0.568353779 -0.617727733 0.040326634 VMA8 vacuolar ATPase V1 domain subunit D YEL052W 0.14519015 0.703914225 0.158885982 0.43034003 AFG1 ATPase family gene YEL053C -0.0673508 0.592794022 -0.26974774 0.022716428 MAK10 glucose-repressible protein required for replication of dsRNA virus YEL055C 0.32732929 0.000951809 -0.094909271 0.213722042 POL5 DNA polymerase V YEL056W 0.395286493 0.078801933 0.090202285 0.325815561 HAT2 subunit of a cytoplasmic histone acetyltransferase YEL057C 0.541567273 0.043346283 0.391633863 0.206094219 hypothetical protein YEL059C-A -0.57813478 0.09806415 0.59895921 0.125611372 SOM1 involved in mitochondrial inner peptidase function YEL059W -0.14489734 0.537558225 0.358595536 0.124503286 hypothetical protein YEL061C 0.253292279 0.454418585 -0.412072528 0.273915435 CIN8 kinesin-related protein involved in establishment and maintenance of mitotic spindle YEL062W 0.176455514 0.5431103 0.31684684 0.12670636 NPR2 Non-membrane-embedded, PEST sequence-containing protein YEL063C -0.57901092 0.051010942 0.4224296 0.033076731 CAN1 arginine permease YEL064C -0.78964838 0.10483026 -0.037929459 0.81000969 similar to amino acid transport proteins YEL065W 0.623246967 0.429025132 0.083447472 0.48380425 SIT1 Ferrioxamine B permease YEL066W -0.45319575 0.421583791 0.570156961 0.217921578 HPA3 histone acetyltransferase complex subunit YEL067C 0.259295992 0.442559806 0.565018226 0.127292496 weak similarity to YKL083w YEL068C -0.79832174 0.036975695 0.281285116 0.259642681 hypothetical protein YEL069C -0.5363826 0.093179076 0.46983103 0.049358476 HXT13 high-affinity hexose transporter YEL070W -1.06894627 0.010600427 0.04623295 0.848219981 strong similarity to E.coli D-mannonate oxidoreductase YEL071W 1.036156571 0.198251377 -0.02913297 0.577182048 DLD3 D-lactate dehydrogenase YEL072W -0.7084363 0.026671707 -0.720483281 0.028670556 hypothetical protein YEL073C 0.950691263 0.387459627 -0.094232024 0.627892455 similarity to YJR108w YEL074W 0.042499175 0.84581291 0.418696436 0.278014253 similarity to subtelomeric encoded proteins YEL075C -0.11694537 0.59391621 0.546382513 0.094710629 strong similarity to subtelomeric encoded proteins YEL076C -0.68930116 0.028490828 0.556596854 0.037642554 hypothetical protein YEL076W-C -0.61515954 0.013022442 0.600998067 0.114525184 hypothetical protein YEL077C -1.12049312 0.003141734 0.435254078 0.241442627 strong similarity to subtelomeric encoded proteins YER001W -0.92158241 0.070827606 -0.248972626 0.1476173 MNN1 Alpha-1,3-mannosyltransferase YER002W 0.781694842 0.03632482 -0.772853997 0.150805416 weak similarity to chicken microfibril-associated protein YER003C 0.49706498 0.411542354 0.35823493 0.064457217 PMI40 mannose-6-phosphate isomerase YER004W 0.185296267 0.518408376 0.412215402 0.058139636 similarity to hypothetical E.coli and C.elegans proteins YER005W -0.19896161 0.291539999 0.059700367 0.53261671 YND1 apyrase (NDPase /NTPase) YER006W 1.18715661 0.049662508 -0.332887808 0.138792989 similarity to P.polycephalum myosin-related protein mlpA YER007W -0.31685305 0.390938418 -0.25389805 0.256643808 PAC2 (putative) tubulin cofactor E, involved in microtubule stability SEC3 encodes the 144 kD and 91 kD components of the Exocyst complex ; the 91 kD component is a C-terminal proteolytic breakdown YER008C 0.013184685 0.935504773 0.12067997 0.267924092 SEC3 product of full length Sec3p YER009W 1.125498361 0.090259381 0.651613619 0.025209974 NTF2 nuclear transport factor, homologous to mammalian cytosolic nuclear import factor NTF2 YER010C -0.11549357 0.610927563 0.569517032 0.081246701 similarity to L.pneumophila dlpA YER011W 3.173635106 0.194033743 0.892090316 0.075359512 TIR1 Cold-shock induced protein of the Srp1p /Tip1p family of serine-alanine-rich proteins YER012W 0.214874793 0.652734298 -0.105789773 0.245341971 PRE1 22.6 kDa proteasome subunit YER013W -0.31311754 0.097941921 -0.122236169 0.335682747 PRP22 helicase-like protein YER014W -0.14248224 0.548221134 -0.216528524 0.080562335 HEM14 protoporphyrinogen oxidase YER015W -1.08653383 0.028264117 -0.119665078 0.25414989 FAA2 Acyl-CoA synthetase (fatty acid activator 2) YER016W 0.42392771 0.230088748 -0.32769884 0.371003473 BIM1 microtubule-binding protein YER017C 0.321179217 0.473830136 0.016762808 0.819725638 AFG3 ATP-dependent metalloprotease YER018C 0.608409537 0.037957119 0.590408462 0.032122367 SPC25 component of spindle pole YER019C-A 0.591794412 0.057266362 0.553482064 0.001935659 SBH2 homologous to Sbh1p YER019W 0.530964282 0.041565297 0.831367976 0.105999988 ISC1 InositolphosphoSphingolipids-phospholipase C YER020W -1.00247284 0.022929428 0.164758676 0.206088851 GPA2 nucleotide binding regulatory protein YER021W -0.26491239 0.172621071 -0.257928275 0.153431222 RPN3 component of the regulatory module of the 26S proteasome, homologous to human p58 subunit YER022W -0.34913585 0.058188196 -0.679956661 0.060471371 SRB4 subunit of RNA polymerase II holoenzyme /mediator complex YER023W -0.3863816 0.239187986 -0.035554966 0.728360268 PRO3 delta 1-pyrroline-5-carboxylate reductase YER024W -0.09141187 0.842768068 -0.08947325 0.313509432 similarity to carnitine O-acetyltransferase Yat1p YER025W 0.785722786 0.017022523 -0.004711989 0.944659626 GCD11 gamma subunit of translational initiation factor eIF-2 YER027C -0.59907859 0.017362791 0.072341078 0.460404646 GAL83 glucose repression protein, a component of the Snf1 complex YER028C 0.395557263 0.123017502 0.169745818 0.051005331 similarity to Mig1p YER029C 0.060435835 0.717542003 -0.446392585 0.093140569 SMB1 U1 snRNP protein YER030W -0.03477296 0.870943298 -0.802488332 0.041247076 similarity to mouse nucleolin YER031C 0.350187306 0.360826982 0.081962878 0.470805003 YPT31 ras-like GTPase, highly homologous to YPT32 YER032W -0.23287507 0.398032991 0.491567133 0.180990708 FIR1 Putative participant in 3' mRNA processing YER033C -0.37051214 0.218533838 0.328759247 0.219842238 ZRG8 zinc regulated gene YER034W -0.2421468 0.203284137 -0.019521955 0.81821575 hypothetical protein YER035W -0.79961972 0.003181901 0.054135947 0.400062917 EDC2 Functions with Edc1p to stimulate mRNA decapping YER036C 0.695997665 0.156776985 -0.070889317 0.187793956 strong similarity to members of YER037W -1.37388592 0.027263351 -0.400454715 0.136855878 PHM8 strong similarity to hypothetical YER038C -0.16362813 0.561126381 -0.015153434 0.872022409 hypothetical protein YER039C -0.53675088 0.112983833 0.40698086 0.185544097 HVG1 (putative) nucleotide sugar transporter YER040W 0.027677093 0.900940113 0.23508607 0.252962954 GLN3 Transcriptional activator of nitrogen-regulated genes YER041W -0.40251896 0.173582491 -0.219977071 0.310660817 YEN1 weak similarity to DNA repair protein Rad2p and Dsh1p YER042W -0.10901661 0.44167315 -0.210773823 0.173981977 MXR1 peptide methionine sulfoxide reductase YER043C 1.241315334 0.289347163 0.378326091 0.054567809 SAH1 putative S-adenosyl-L-homocysteine hydrolase YER044C -0.7285593 0.02914278 0.440999044 0.051876826 involved in synthesis of ergosterol YER044C-A 1.117655734 0.241502598 -0.27132645 0.018568972 MEI4 mRNA is meiosis-specific and has 88 bp intron at 5' end spliced independently of MER1. YER046W -0.67245901 0.060102146 0.399552624 0.098533136 hypothetical protein YER048C -0.34119595 0.079673365 -0.460429862 0.129244905 CAJ1 homologous to E. coli DnaJ YER048W-A 0.63218342 0.029632386 0.067619093 0.115622284 dnaJ homolog YER049W 1.199754515 0.168538326 -0.308516145 0.053036603 strong similarity to hypothetical YER050C 0.409900521 0.023922948 -0.59560845 0.032048394 RSM18 protein of the small subunit of the mitochondrial ribosome YER051W -0.68741924 0.015019296 -0.348758188 0.06113218 similarity to C.elegans hypothetical YER052C 0.053937399 0.81141781 0.10233117 0.323964091 HOM3 Aspartate kinase (L-aspartate 4-P-transferase) (EC 2.7.2.4) YER053C -1.30991767 0.00814306 -0.285673053 0.022506636 strong similarity to mitochondrial YER054C -1.46437674 0.007797164 0.262312248 0.310548983 GIP2 (putative) regulator of Glc7, a PP1 family protein phosphatase YER055C 0.918639886 0.12511321 0.008035864 0.939606059 HIS1 ATP phosphoribosyltransferase YER056C 0.948740102 0.19763909 0.169017913 0.313612377 FCY2 purine-cytosine permease YER056C-A 1.171852004 0.026749893 0.409069495 0.072603787 RPL34A Ribosomal protein L34A YER057C -0.29141481 0.158922064 0.584955754 0.108191796 HIG1 heat-regulated protein YER058W 0.368581591 0.114589159 -0.447432266 0.180303655 PET117 cytochrome c oxidase assembly factor YER059W -0.48637349 0.023906705 -0.286446993 0.018510421 PCL6 PHO85 cyclin YER060W 0.065107948 0.820363419 0.812806244 0.05976457 FCY21 purine-cytosine permease YER061C 0.006687598 0.984077315 -0.148362832 0.235472137 CEM1 Protein homologous to beta-keto-acyl synthase YER063W -0.78808031 0.002726506 -0.180321213 0.241575451 THO1 (putative) involved in transcription YER064C 0.573209329 0.171199291 -0.191288321 0.011279422 similarity to hypothetical protein YIL056w YER065C -0.99600514 0.065285652 0.406477802 0.094173127 ICL1 isocitrate lyase YER066C-A -2.19890689 0.000334639 0.035518239 0.756006142 hypothetical protein YER066W -0.80272137 0.001924262 0.09718046 0.420566 strong similarity to cell division control protein Cdc4p YER067W -2.20033499 0.003723448 0.625438527 0.044229988 strong similarity to hypothetical protein YIL057c YER068W 0.366428029 0.138441471 0.226061084 0.06430291 MOT2 putative zinc finger protein YER069W 0.153417053 0.768672752 -0.331663238 0.217839979 ARG5,6 N-acetyl-gamma-glutamyl-phosphate reductase and acetylglutamate kinase YER070W 0.778789323 0.275682675 0.375799458 0.039332451 RNR1 ribonucleotide reductase YER071C 0.155973293 0.056351981 -0.081798647 0.025701073 hypothetical protein YER072W -0.47441952 0.293938017 0.820056893 0.02370575 VTC1 Homolog of S. pombe nrf1 (78 % identical in predicted amino acid sequence) YER073W -0.41916357 0.014894642 -0.028720888 0.809799268 ALD5 mitochondrial Aldehyde Dehydrogenase YER074W 1.118645861 0.072797967 -0.024958046 0.840624872 RPS24A 40S ribosomal protein S24A YER075C -0.14424749 0.755818484 0.107850213 0.364134219 PTP3 Protein tyrosine phosphatase YER076C -0.6710532 0.079655109 0.042041777 0.223116826 similarity to killer toxin Khr1p YER077C 0.656599861 0.041681647 -0.541680947 0.057857348 hypothetical protein YER078C -0.32615331 0.068451342 -0.177811931 0.136126824 similarity to E.coli X-Pro aminopeptidase II YER079W -1.07931513 0.001275629 -0.128182193 0.213180252 hypothetical protein YER080W -0.48194536 0.006874029 -0.151992062 0.197897002 hypothetical protein YER081W 0.496728494 0.25300829 0.117703954 0.430111756 SER3 3-phosphoglycerate dehydrogenase YER082C 1.269738114 0.005208242 -0.298055699 0.333707368 similarity to M.sexta steroid regulated MNG10 protein YER084W -0.44802761 0.368420377 0.185032223 0.804316977 questionable ORF YER085C 0.307231373 0.659170846 0.283561729 0.528422784 weak similarity to myosins YER086W 0.625126774 0.073160109 -0.057180288 0.309716361 ILV1 threonine deaminase YER087C-A 0.647897779 0.042390999 0.736545474 0.070823376 SBH1 homologous to Sbh2p YER087W 0.213958824 0.319412831 -0.238681062 0.160589622 similarity to E.coli prolyl-tRNA synthetase YER088C -0.46840666 0.072411058 0.608894283 0.160393351 DOT6 nuclear protein with Myb domain involved in telomeric silencing YER089C -0.30948419 0.043429856 0.440367292 0.078593093 PTC2 Protein phosphatase type 2C YER090W 0.538825966 0.307196867 -0.146107159 0.048924689 TRP2 anthranilate synthase Component I vitamin B12-(cobalamin)-independent isozyme of methionine synthase (also called N5-methyltetrahydrofolate homocysteine methyltransferase YER091C -0.47032438 0.378878988 0.407410181 0.035073447 MET6 or 5-methyltetrahydropteroyl triglutamate homocysteine methyltransferase) YER091C-A 0.088179248 0.845359135 0.004501228 0.978359201 hypothetical protein - identified by SAGE YER092W 0.532301846 0.025790949 -0.085677825 0.053477399 similarity to E.coli prolyl-tRNA synthetase YER093C 0.702766351 0.023484952 0.263431679 0.033938866 weak similarity to S.epidermidis PepB protein YER093C-A -0.20521317 0.351753085 0.31198502 0.198451499 similarity to hypothetical protein YBL059w YER094C 0.452961431 0.260380522 0.220761826 0.275158055 PUP3 20S proteasome subunit beta3_sc RecA homolog ; Rad51p colocalizes to ~ 65 spots with Dmc1p prior to synapsis (independently of ZIP1 and DMC1), and interacts with Rad52p YER095W 0.693565471 0.201799767 0.176279855 0.583079002 RAD51 and Rad55p ; human Rad51p homolog interacts with Brca2 protein which has been implicated in causing breast cancer YER096W -2.06256564 0.00128458 -0.36949923 0.08528454 SHC1 sporulation-specific homolog of csd4 YER097W -0.12176411 0.715010494 0.24179481 0.239910384 weak similarity to ribosomal S3 proteins YER098W -0.46015171 0.090731915 0.189894258 0.412084642 UBP9 ubiquitin carboxyl-terminal hydrolase YER099C -0.2153853 0.301972864 0.136720828 0.31459569 PRS2 ribose-phosphate pyrophosphokinase 2 YER100W 0.043410968 0.714741026 -0.133831227 0.16794667 UBC6 ubiquitin-conjugating enzyme YER101C -0.90656538 0.029059881 -0.05227519 0.521589441 AST2 involved in targeting of plasma membrane [H+]ATPase YER102W 2.076633921 0.067946003 0.196567561 0.245329992 RPS8B Ribosomal protein S8B (S14B) (rp19) (YS9) YER103W -2.46391839 0.001099776 0.058866473 0.734569223 SSA4 member of 70 kDa heat shock protein family YER104W -0.34399706 0.288723381 -0.057675984 0.3799567 RTT105 same phenotype as RTT101, 102, 103, 104 YER105C -0.13763518 0.026925989 0.081107134 0.010144546 NUP157 Nucleoporin similar to Nup157p and to mammalian Nup155p YER106W 0.401711254 0.465768109 -0.569699871 0.304515475 hypothetical protein YER107C 0.454831539 0.117502907 0.161724193 0.356302514 GLE2 homologous to S. pombe RAE1 gene ; 2-hybrid analysis demonstrates an interaction with Srp1p and Rip1p ; copurifies with Nup116p YER109C 0.040693367 0.846926201 -0.108503677 0.258833734 FLO8 putative transcriptional activator of FLO1 YER110C 0.552445294 0.228599039 0.192089397 0.090599551 KAP123 Karyopherin beta 4 YER111C 0.089205277 0.175218976 -0.188855835 0.367796755 SWI4 transcription factor YER112W 0.590781163 0.275417361 -0.595226168 0.068451166 LSM4 U6 snRNA associated protein YER113C -0.11725167 0.560952184 -0.194417451 0.29144341 similarity to Emp70p YER114C -0.12672944 0.78022673 0.062056723 0.846693983 BOI2 involved in bud formation, has SH3 domain YER115C -0.71472748 0.11916246 -0.216942142 0.147208105 SPR6 involved in sporulation YER116C 0.29667486 0.388123752 -0.247858975 0.063784328 zinc-finger protein YER117W 2.319339736 0.092618174 0.466867458 0.126093501 RPL23B Ribosomal protein L23B (L17aB) (YL32) YER118C 1.319027065 0.103266759 0.429769438 0.031099206 SHO1 Transmembrane osmosensor YER119C -0.91754573 0.017509107 1.082945438 0.062330537 similar to amino acid transport proteins YER120W 0.302813814 0.237473144 0.515730561 0.102430426 SCS2 involved in inositol metabolism, regulator of INO1 expression YER121W -0.94641432 0.016112353 0.117805432 0.360931597 hypothetical protein YER122C 0.391807498 0.06323217 -0.256240071 0.371785903 GLO3 Zinc-finger-containing protein with similarity to Gcs1p and Sps18p YER123W 0.128143448 0.365362108 -0.263614916 0.079322395 YCK3 plasma membrane-bound casein kinase I homolog YER124C -0.31143283 0.650969076 -0.016176873 0.880714953 weak similarity to Dictyostelium WD40 repeat protein 2 YER125W -0.59429104 0.040615867 0.314157941 0.218895318 RSP5 Rsp5p encodes a hect (homologous to E6-AP C terminus) and encodes a ubiquitin-protein ligase (E3 enzyme) YER126C 1.515316797 0.147776832 -0.403099366 0.15096468 Lethal with conditional pap1 allele YER127W 1.527539636 0.109307349 -0.511624634 0.097699427 LCP5 involved in ribosomal RNA processing YER128W 0.080266333 0.599581339 -0.133843055 0.603533083 high copy suppressor of temperature sensitive cdc17 (DNA polymerase alpha) mutations YER129W -0.25708566 0.400327792 0.000714572 0.985559945 PAK1 DNA polymerase alpha suppressing protein kinase YER130C 0.12157171 0.764604538 -0.295424817 0.060284414 similarity to Msn2p and weak similarity to Msn4p YER131W 0.771749498 0.071319758 0.089119006 0.601657361 RPS26B Ribosomal protein S26B YER133W -0.401109 0.015856517 -0.774539395 0.030042148 GLC7 protein phosphatase type I YER134C -0.12970269 0.372260409 -0.118234741 0.195966824 weak similarity to S.pombe SPBC13G1 and C.elegans F26F2.d hypothetical proteins YER135C -0.40388375 0.495957048 -0.28743071 0.661534437 hypothetical protein YER136W -0.58071722 0.064426618 -0.130472603 0.118824705 GDI1 GDP dissociation inhibitor YER137C 0.090322797 0.79115638 -0.496555878 0.107253787 weak similarity to Mycoplasma hominis P120 protein YER137C-A 0.570169869 0.093148838 0.268025026 0.050186283 TyA gag protein. Gag processing produces capsid proteins. YER138W-A 0.390037442 0.244377505 0.160909088 0.070752583 questionable ORF - identified by SAGE YER139C -0.66501214 0.000847934 -0.461819017 0.041338737 similarity to hypothetical protein YDR066c YER140W 0.117255053 0.67365522 -0.12171291 0.110293807 hypothetical protein YER141W -0.23144709 0.503999017 0.074085115 0.786175947 COX15 cytochrome oxidase assembly factor YER142C -0.51245625 0.091825098 -0.388615335 0.046081736 MAG1 3-methyladenine DNA glycosylase YER143W -0.06743518 0.830928696 0.103012529 0.390400758 DDI1 DNA Damage Inducible ; binds to T- and V- snare complexes YER144C -0.07788596 0.812717472 0.778417636 0.058698836 UBP5 Putative Ubiquitin-specific protease YER145C 0.438765749 0.384281406 0.099819034 0.366093241 FTR1 Iron permease YER146W 0.526627673 0.18735187 0.105041282 0.37237749 LSM5 Sm-like protein YER147C -0.45384448 0.420300523 0.00677716 0.952845752 weak similarity to mouse NAD(P)H dehydrogenase (quinone) YER148W 0.763679521 0.031776441 -0.372759141 0.127119119 SPT15 TATA-binding protein (tfIId) YER149C -0.31148224 0.236538577 -0.234934343 0.165505061 PEA2 Protein with coiled-coil domain YER150W -2.13279042 5.70628E-06 0.775621591 0.200223178 SPI1 similar to Sed1 ; highly expressed in stationary phase YER151C -0.02441145 0.920019572 -0.168634223 0.23667714 UBP3 Ubiquitin-specific protease YER152C -0.63603712 0.018226899 0.491045503 0.03395602 weak similarity to E.coli hypothetical protein f470 YER154W -0.21931015 0.382829959 0.385446985 0.201828117 OXA1 involved in cytochrome c oxidase and ATP synthase assembly YER156C 0.552355969 0.144521024 -0.096498978 0.263905508 similarity to hypothetical C. elegans protein C27H6.5 Sec34p is a 92.5 kD protein that is primarily cytosolic but a small pool associates with the particulate fraction upon centrifugation at 150,000xg. YER157W 0.45088621 0.209702388 -0.252703899 0.01575924 SEC34 Sec34p stably associates with Sec35p, a protein implicated in vesicle docking, to form a multiprotein comple YER158C -1.48995173 0.001280192 -0.005116252 0.971329828 weak similarity to Afr1p YER159C 0.631863273 0.244378323 -0.139341215 0.227908785 BUR6 Transcriptional regulator which functions in modulating the activity of the general transcription machinery in vivo YER160C 1.181353911 0.025645213 0.417677411 0.009619628 transposon Ty putative peptide with frame shift YER161C -0.15399064 0.050373655 -0.390131674 0.177155041 SPT2 non-specific DNA binding protein (sin1) YER162C -0.44125702 0.099932395 -0.519851475 0.040983481 RAD4 Nucleotide excision repair protein YER163C 0.232733028 0.712787017 0.143641981 0.257125252 weak similarity to E.coli cation transport protein YER164W -0.05965376 0.863041994 0.115650872 0.456728862 CHD1 transcriptional regulator YER165W -0.05206023 0.89187975 0.031310007 0.758543539 PAB1 Poly(A) binding protein, cytoplasmic and nuclear YER166W 0.138081502 0.723618247 0.745183467 0.154550072 similarity to ATPase P.falciparum ATPase 2 YER168C -0.15615899 0.402105006 -0.289413698 0.04039311 CCA1 tRNA nucleotidyltransferase (tRNA CCA-pyrophosphorylase) YER169W -0.40749239 0.158343032 0.041598109 0.689937025 RPH1 Repressor of PHR1 transcription ; binds to PHR1 URS YER170W 0.084521989 0.35324402 -0.092601157 0.730220471 ADK2 Adenylate kinase (mitochondrial GTP:AMP phosphotransferase) YER171W 0.44395914 0.167540592 -0.374956976 0.063865374 RAD3 DNA repair helicase component of transcription factor b YER172C -0.20399519 0.406884666 -0.063266587 0.429990429 BRR2 putative ATP-dependent RNA helicase YER173W -0.08350545 0.350661753 -0.269333953 0.161919196 RAD24 (putative) cell cycle exonuclease YER174C -0.24860609 0.200560953 -0.189281804 0.014570593 GRX4 Protein with glutaredoxin activity YER175C -0.3741393 0.483126384 -0.455116077 0.026553244 putative methyltransferase YER176W -0.57362416 0.02508399 -0.449695781 0.06687362 ECM32 DNA Helicase I YER177W 0.658907557 0.11943742 0.353166678 0.028275109 BMH1 Homolog of mammalian 14-3-3 proteins YER178W 0.170728596 0.607529599 0.250361871 0.276110074 PDA1 alpha subunit of pyruvate dehydrogenase (E1 alpha) meiosis-specific protein related to RecA and Rad51p. Dmc1p colocalizes with Rad51p to discrete subnuclear sites in nuclear spreads during YER179W -0.1731058 0.239596192 0.340965645 0.013294406 DMC1 mid prophase, briefly colocalizes with Zip1p, and then disappears by pachytene YER180C -0.1944957 0.327585258 -0.111846696 0.548650285 ISC10 involved in meoisis, spore formation YER181C 0.231334756 0.505828875 -0.176404136 0.377390106 questionable ORF YER182W -0.23002645 0.39205277 -0.286310721 0.037659185 hypothetical protein YER183C 0.551395257 0.009248904 -0.021608911 0.826341051 FAU1 5,10-methenyltetrahydrofolate synthetase YER184C -0.01751418 0.960951261 -0.293933943 0.002728812 similarity to multidrug resistance proteins Pdr3p and Pdr1p YER185W 0.557878568 0.288705239 -0.081021094 0.693834694 strong similarity to Rtm1p YER186C -1.64480744 0.002427008 -0.378508795 0.036838594 weak similarity to hypothetical protein YMR316w YER187W 0.084126279 0.904811026 0.213037254 0.422649731 similar to killer toxin YER187W-A 0.316263046 0.633358876 0.088500738 0.422649731 KHS1 Killer toxin YER188W 0.763182552 0.558819396 -0.103085091 0.788983337 hypothetical protein YER189W -0.76040885 0.010079099 0.406365569 0.029429254 strong similarity to subtelomeric encoded proteins YER190W -1.08120685 0.002489209 0.643798115 0.111371606 YRF1-2 Y'-helicase protein 1 YFL001W 0.45414667 0.013205244 -0.017383584 0.937229105 DEG1 Depressed growth-rate protein YFL002C 0.024004103 0.911678196 -0.584828944 0.117469606 SPB4 ATP-dependent RNA helicase The TyB Gag-Pol protein. Gag processing produces capsid proteins. Pol is cleaved to produce protease, reverse transcriptase, and integrase YFL002W-B -0.16363352 0.537939501 -0.029293055 0.641473679 activities. YFL003C 0.137145363 0.390621322 0.045160165 0.659248247 MSH4 meiosis specific protein, E.coli MutS protein, localizes to discrete sites on meiotic chromosomes YFL004W -1.05904695 0.031581147 -0.369281017 0.031501139 VTC2 polyphosphate synthetase (putative) YFL005W -0.15659272 0.428446224 -0.302546722 0.01639448 SEC4 Ras-like small GTP-binding protein YFL006W -0.34034978 0.260586393 0.406858747 0.126900582 hypothetical protein YFL008W 0.089638109 0.671967162 -0.666337646 0.005889652 SMC1 SMC chromosomal ATPase family member YFL009W -0.34079258 0.007210986 -0.099656425 0.145429181 CDC4 part of a ubiquitin ligase complex YFL010C 0.447473986 0.102118991 0.308489937 0.027636501 questionable ORF YFL011W -0.08177175 0.358312642 0.201440536 0.327632764 HXT10 high-affinity hexose transporter YFL012W -0.37546142 0.490870089 0.263629031 0.19490163 hypothetical protein YFL013C -0.05812814 0.617620722 -0.465893705 0.083996628 weak similarity to Dictyostelium protein kinase YFL014W -2.91601589 0.000496719 -0.446564594 0.287591881 HSP12 12 kDa heat shock protein YFL015C 0.128326848 0.618226465 0.080643212 0.863734123 weak similarity to YDR504c YFL016C 0.115314195 0.31204124 -0.231276598 0.129066373 MDJ1 DnaJ homolog involved in mitochondrial biogenesis and protein folding YFL017C 0.06749962 0.545167552 0.280183649 0.134141133 GNA1 glucosamine-phosphate N-acetyltransferase YFL017W-A 0.160406456 0.206067724 0.483440341 0.053977065 SMX2 snRNP G protein (the homologue of the human Sm-G) YFL018C -1.08418508 0.003100238 -0.179089195 0.023332266 LPD1 dihydrolipoamide dehydrogenase precursor (mature protein is the E3 component of alpha-ketoacid dehydrogenase complexes) YFL019C 0.105981521 0.654843906 0.634359511 0.168602428 hypothetical protein YFL020C 0.230060723 0.620650143 0.584177879 0.150993117 PAU5 member of the seripauperin (PAU) family YFL021W -0.64125536 0.143379631 0.633265958 0.077845911 GAT1 transcriptional activator with GATA-1-type Zn finger DNA-binding motif YFL022C 0.207802634 0.271090919 0.442073942 0.047005352 FRS2 Phenylalanyl-tRNA synthetase, beta subunit, cytoplasmic YFL023W -0.15622884 0.559076407 -0.824144846 0.015885694 similarity to repeat structures in a Plasmodium falciparum protein (MESA) that binds human erythrocyte protein 4.1. YFL024C 0.07405782 0.670970839 -0.222734694 0.077964588 EPL1 Probable chromatin protein because of homology to Drosophila Enahncer of Polycomb YFL025C 0.421717269 0.145115806 0.246521191 0.202120033 BST1 negative regulator of COPII vesicle formation YFL026W 1.251944317 0.200366694 0.484008409 0.048623833 STE2 alpha-factor pheromone receptor ; seven-transmembrane domain protein YFL027C 0.313698938 0.325761831 -0.426581957 0.082383596 weak similarity to P.falciparum Pfmdr2 protein YFL028C 0.11351165 0.759562699 -0.563458169 0.017574936 CAF16 ABC ATPase YFL029C -0.20627297 0.081689528 -0.244415633 0.044640974 CAK1 Cyclin-dependent kinase-activating kinase YFL030W -2.18507371 0.000840074 -0.029626183 0.940774483 similarity to several transaminases YFL031W -0.47132143 0.130307304 1.013285685 0.179832526 HAC1 bZIP (basic-leucine zipper) protein YFL032W 0.204676762 0.383120557 1.547834939 0.165149017 questionable ORF YFL034C-B 0.804957067 0.132525978 0.305051389 0.142636862 MOB2 Mob1p-like protein YFL034W -0.17939623 0.242696472 -0.076372269 0.696353561 similarity to hypothetical S. pombe protein and to C.elegans F35D11 protein YFL036W 0.20581969 0.434363199 0.087817259 0.385373314 RPO41 mitohcondrial RNA polymerase YFL037W 0.657742143 0.333425768 0.015569657 0.812810694 TUB2 beta-tubulin YFL038C 0.254487542 0.473918892 0.169731275 0.347574778 YPT1 Ras-like GTP-binding protein ; most similar to mammalian Rab1A protein YFL039C 1.202849588 0.228014499 0 #DIV/0! ACT1 Actin YFL040W -0.189092 0.512534201 -0.031469625 0.882069504 similarity to yeast glucose transport proteins YFL041W -0.04284735 0.845082255 0.272184076 0.105179833 FET5 multicopper oxidase, type 1 integral membrane protein YFL042C -0.85664732 0.048373203 -0.041589822 0.831224901 similarity to hypothetical protein YLR072w YFL044C -0.47377886 0.059188311 0.111813416 0.127296871 weak similarity to human dystrophin YFL045C 0.974428999 0.189471471 0.096015385 0.197553347 SEC53 phosphomannomutase YFL046W 0.290262327 0.230880015 -0.493725188 0.061256813 weak similarity to middle part of C.elegans myosin heavy chain A YFL047W 0.863926421 0.202631287 -0.019680145 0.770405709 similarity to S.pombe hypothetical protein SPAC2F7.18c YFL048C -0.01364779 0.951204171 -0.131393231 0.210658634 EMP47 47 kDa type I transmembrane protein localized to the Golgi YFL049W 0.363255561 0.096833534 -0.326570519 0.098060548 weak similarity to Npl6p YFL050C -0.25027449 0.119019944 0.001501196 0.987046298 ALR2 (putative) ion transporter YFL051C -0.03712187 0.959245029 0.344229182 0.448771883 putative pseudogene YFL052W -0.17863344 0.260265259 0.00720234 0.986586318 strong similarity to Mal63p, YPR196w and Mal13p YFL053W -0.2856803 0.268649812 0.923067577 0.03229297 DAK2 dihydroxyacetone kinase YFL054C -0.45702961 0.214419548 0.006736539 0.968984986 similarity to channel proteins YFL055W -0.0933733 0.79502653 0.431156044 0.131273223 AGP3 Amino acid permease YFL056C -0.68402157 0.069803552 0.106423567 0.582497613 AAD6 Hypothetical aryl-alcohol dehydrogenase (AAD) YFL057C -0.23041875 0.254297973 0.311513204 0.154042213 strong similarity to aryl-alcohol dehydrogenases YFL058W 4.802122735 0.383094082 0.463856465 0.387792531 THI5 a thiamine regulated pyrimidine precursor biosynthesis enzyme YFL059W 1.304299163 0.002251963 0.425371583 0.165185809 SNZ3 member of the stationary phase-induced gene family YFL061W 0.827559336 0.011530528 0.118529622 0.000126846 similarity to M.verrucaria cyanamide hydratase YFL062W 0.28389828 0.569196636 -0.034057911 0.824063909 COS4 similar to subtelomerically-encoded proteins YFL063W 0.268122435 0.39801209 0.488671709 0.474458271 strong similarity to subtelomeric encoded proteins YFL064C -0.6405705 0.050960247 0.505039563 0.08794111 strong similarity to subtelomeric encoded proteins YFL065C -0.54427355 0.067350593 0.706402926 0.042813465 strong similarity to subtelomeric encoded proteins YFL066C -1.2411318 0.014928361 0.694259615 0.248718982 strong similarity to subtelomeric encoded proteins YFL067W -1.36871764 0.006430003 0.711190268 0.117606387 similarity to mouse period clock protein YFL068W -1.02589817 0.021531388 0.352936011 0.28993442 weak similarity to hypothetical E.coli protein YFR001W 0.894250622 0.063345822 -0.893991505 0.112682463 LOC1 Double-stranded RNA-binding protein YFR002W 0.447455667 0.168158103 -0.330558402 0.102818977 NIC96 96 kDa nucleoporin-interacting component YFR003C -0.54738422 0.056964043 -0.192148411 0.189234945 hypothetical protein YFR004W 0.211079933 0.514842258 -0.224931979 0.194195599 RPN11 Similar to S. pombe PAD1 gene product YFR005C 0.824564823 0.109391834 -0.038146813 0.61834184 SAD1 SnRNP assembly defective YFR006W 0.49374042 0.125615394 0.05051867 0.717808688 similarity to X-Pro dipeptidases YFR007W -0.38958673 0.196646795 -0.239195879 0.034615543 weak similarity to YER176w YFR008W -0.47839069 0.00266374 -0.570956294 0.018033779 weak similarity to human centromere protein E YFR009W 0.688032791 0.044003043 -0.204732562 0.068298283 GCN20 Member of ATP-binding cassette (ABC) family of proteins YFR010W -0.14642223 0.235870643 -0.437901559 0.118228379 UBP6 (putative) ubiquitin-specific protease YFR011C 0.007141633 0.969952243 -0.168449677 0.429076369 ochre suppressor tyr-tRNA YFR012W -1.37878326 0.022778606 -0.474856986 0.34934955 similarity to hypothetical protein YOL019w YFR013W -0.01398348 0.955329186 -0.28346937 0.194656582 IOC3 ISWI One Complex YFR014C -1.37330016 0.008671943 -0.046836886 0.642420837 CMK1 Calmodulin-dependent protein kinase YFR015C -2.15659488 6.5854E-05 0.351214704 0.114614736 GSY1 Glycogen synthase (UDP-gluocse--starch glucosyltransferase) YFR016C -0.3752958 0.146002093 -0.1575837 0.466581505 similarity to mammalian neurofilament proteins and to Dictyostelium protein kinase YFR017C -1.62428625 0.003116802 0.642692806 0.097841539 hypothetical protein YFR018C 0.211335614 0.205714167 0.504760513 0.203587299 similarity to human glutaminyl-peptide cyclotransferase YFR020W 0.026404487 0.945012365 0.164173149 0.271174778 hypothetical protein YFR021W -0.44566557 0.091063032 0.285246524 0.162134774 similarity to hypothetical protein YPL100w YFR022W -0.3635142 0.525078163 0.439531488 0.243444183 similarity to Rod1p YFR023W -0.72942636 0.008952884 -0.344710633 0.569666052 PES4 poly(A) binding protein ; related to PES4 protein homolog YHR015w YFR024C -0.02741103 0.945730915 0.168345966 0.303913615 YFR024C-A -0.11209022 0.700483252 0.411553856 0.190585804 similarity to Acanthamoeba myosin heavy chain IC and weak similarity to other myosin class I heavy chains YFR025C 0.235839776 0.60226827 -0.149363049 0.09229715 HIS2 Histidinolphosphatase YFR026C -0.63709358 0.188394004 0.167374402 0.527846254 hypothetical protein YFR027W 0.076644823 0.518565707 0.146854347 0.342197336 ECO1 involved in establishment of cohesion between sister chromatids YFR028C 0.857697722 0.093176874 0.23868094 0.050585399 CDC14 soluble tyrosine-specific protein phosphatase YFR029W -0.03553586 0.911762323 0.515406128 0.119213614 PTR3 regulator of peptide permease YFR030W -0.79104887 0.082032483 0.514281758 0.072390553 MET10 subunit of assimilatory sulfite reductase YFR031C 0.734882267 0.014077235 -0.032367896 0.577255905 SMC2 SMC chromosomal ATPase family member YFR032C 0.292316196 0.686814081 0.342755771 0.188075125 weak similarity to S.pombe polyadenylate-binding protein, YPR112c and Sbp1p YFR033C -1.5623361 0.008254556 -0.19882711 0.008135648 QCR6 ubiquinol-cytochrome c oxidoreductase subunit 6 (17 kDa) YFR034C -0.00741145 0.982885402 0.110183032 0.202303237 PHO4 myc-type helix-loop-helix transcription factor YFR035C 0.738644613 0.006794544 0.180885805 0.286344404 hypothetical protein YFR036W 0.403694359 0.017390726 0.380134418 0.003215169 CDC26 cell division control protein YFR037C 0.07734959 0.265496037 -0.253200468 0.072778796 RSC8 chromatin remodeling complex subunit YFR038W -0.18715605 0.568271597 -0.205415844 0.064203074 strong similarity to mouse lymphocyte specific helicase YFR039C -0.01796693 0.959466532 -0.139045627 0.009855866 similarity to hypothetical protein YGL228w YFR040W -0.37758438 0.105205116 -0.378824944 0.019237231 SAP155 cell cycle protein, interacts with Sit4 YFR041C -0.33270446 0.220502618 -0.664017903 0.069316991 weak similarity to dnaJ-like heat shock proteins YFR042W 0.248667229 0.524980278 0.449788754 0.044539874 hypothetical protein YFR043C -0.23788364 0.32091714 0.09358608 0.260452317 hypothetical protein YFR044C 0.133708856 0.163525287 0.536425417 0.173392333 similarity to hypothetical protein YBR281c YFR045W -0.10267085 0.306676772 0.229796082 0.354406975 similarity to mitochondrial citrate transport proteins YFR046C -0.37120781 0.038255029 -0.332171379 0.379576189 hypothetical protein YFR047C -0.30161436 0.430683724 0.263317456 0.389584507 strong similarity to human quinolinate phosphoribosyltransferase YFR048W -0.42317036 0.097798217 -0.138685679 0.147503188 similarity to hypothetical S.pombe protein SPAC12G12.14 and to YDL001w and YDR282c YFR049W -1.27288193 0.000505242 0.43404344 0.007322835 YMR31 mitochondrial ribosomal protein (precursor) YFR050C 0.109880538 0.713875621 0.360929248 0.017572807 PRE4 proteasome subunit necessary for peptidyl glutamyl peptide hydrolyzing activity YFR051C 0.056824119 0.703369845 0.220168457 0.326127304 RET2 vesicle coat component YFR052W 0.10730818 0.602595573 -0.262306 0.097267871 RPN12 cytoplasmic 32 - 34 kDa protein YFR053C 0.786166686 0.583463747 0.506590529 0.116846358 HXK1 Hexokinase I (PI) (also called Hexokinase A) YFR054C -0.6449174 0.161875654 0.045707234 0.687804758 hypothetical protein YFR055W 2.363183774 0.33152012 -0.223699047 0.077438351 strong similarity to beta-cystathionases YFR056C 1.34935445 0.279096261 -0.27220436 0.217407971 questionable ORF YFR057W 0.024747785 0.974520488 -0.246439188 0.551526002 weak similarity to Cha4p YGL001C 0.86689434 0.341822956 0.188595458 0.139111138 ERG26 C-3 sterol dehydrogenase YGL002W -0.28857167 0.149859179 -0.094970422 0.057973425 ERP6 p24 protein involved in membrane trafficking YGL003C -0.51494103 0.142259087 0.080340399 0.422531542 CDH1 protein required for Clb2 and Ase1 degradation YGL004C -0.29849319 0.230422963 -0.120826934 0.158246623 weak similarity to Tup1p YGL005C -1.36357966 0.000203822 -0.763077534 0.011690124 weak similarity to Xenopus kinesin-related protein Eg5 YGL006W -1.08557718 0.028345361 0.283309006 0.114228854 PMC1 putative vacuolar Ca2+ ATPase YGL007W -0.72961984 0.063218927 -0.085174672 0.693595776 questionable ORF YGL008C 0.778073565 0.53624709 0.232984725 0.237435049 PMA1 plasma membrane H+-ATPase YGL009C -0.07500064 0.253927277 0.081078401 0.12705699 LEU1 isopropylmalate isomerase YGL010W -0.26337441 0.470973013 0.334821654 0.070978997 similarity to hypothetical S. pombe protein YGL011C 0.069463769 0.823239529 -0.064414701 0.191295004 SCL1 Proteasome subunit YC7alpha /Y8 (protease yscE subunit 7) YGL012W 1.700655618 0.138631954 0.478962538 0.12871263 ERG4 Sterol C-24 reductase YGL013C 0.205048828 0.493667088 -0.065759231 0.213174266 PDR1 zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type YGL014W 0.406013118 0.342703172 0 #DIV/0! similarity to Drosophila pumilio protein and Mpt5p protein YGL015C 0.619172674 0.437358382 0.058985183 0.81844225 hypothetical protein YGL017W 0.046021296 0.786286744 0.065497474 0.300748525 ATE1 arginyl-tRNA-protein transferase YGL018C 0.343622263 0.34037542 0.053265562 0.538299838 JAC1 member of the 20-kDa J-protein family of co-chaperones ; homolog of E. coli Hsc20 co-chaperone protein YGL019W 0.092717221 0.378061275 0.228732518 0.246429935 CKB1 beta (38kDa) subunit of casein kinase II (CKII) YGL020C 0.29551445 0.059585509 0.009153369 0.934164968 hypothetical protein YGL021W 0.868493912 0.187871353 -0.071516413 0.782574474 ALK1 DNA damage-responsive protein YGL023C -0.56105195 0.197226227 -0.059630484 0.629633276 PIB2 similar to Fab1 and Vps27 ; involved in telomere-proximal repression of gene expression YGL025C 0.382226401 0.18735377 0.450901649 0.016070181 PGD1 RNA polymerase II mediator subunit YGL026C -0.35064629 0.00316749 0.158510691 0.523536952 TRP5 tryptophan synthetase YGL027C -0.26628041 0.053158797 0.120102261 0.472410693 CWH41 glucosidase I YGL028C 1.090991868 0.372389189 0.659626997 0.084090978 SCW11 soluble cell wall protein YGL029W 1.354435262 0.268339881 -1.018154608 0.083532505 CGR1 coiled-coil protein YGL030W 2.178075603 0.02767725 0.512600129 0.038983735 RPL30 Large ribosomal subunit protein L30 (L32) (rp73) (YL38) YGL031C 1.254458262 0.099772146 -0.056718833 0.792606769 RPL24A Ribosomal protein L24A (rp29) (YL21) (L30A) YGL032C 0.484283683 0.167490133 0.674204098 0.078692609 AGA2 adhesion subunit of a-agglutinin YGL033W -0.01071648 0.961772953 0.195460177 0.438441633 HOP2 Meiosis-specific gene required for the pairing of homologous chromosomes YGL034C -0.12551114 0.759150907 0.540594797 0.322736834 questionable ORF YGL035C 0.706635422 0.325975508 0.282088029 0.001972402 MIG1 C2H2 zinc finger protein which resembles the mammalian Egr and Wilms tumour proteins YGL036W 0.072466498 0.634115347 0.22438575 0.030948737 MTC2 Mtf1 Two Hybrid Clone 2 YGL037C -0.29033452 0.463075731 0.21638862 0.106631185 PNC1 pyrazinamidase and nicotinamidase YGL038C -0.96316023 0.006983747 0.316838213 0.190390675 OCH1 membrane-bound alpha-1,6-mannosyltransferase YGL039W 1.110410753 0.110944232 0.040639458 0.743016642 similarity to V. vinifera dihydroflavonol reductase YGL040C -0.52582562 0.073201848 -0.027356534 0.617584977 HEM2 delta-aminolevulinate dehydratase (porphobilinogen synthase) YGL041C 0.203117838 0.544379172 0.078643652 0.170670531 weak similarity to YJL109c YGL042C -0.02526342 0.751771602 -0.106997782 0.616894002 questionable ORF YGL043W 0.240191672 0.044658011 -0.662870825 0.10005712 DST1 RNA polymerase II elongation factor YGL044C 0.418145897 0.018268619 -0.098791071 0.035973862 RNA15 component of the cleavage and polyadenylation factor CF I involved in pre-mRNA 3'-end processing YGL045W -0.31014338 0.122706538 -0.025196832 0.848194136 hypothetical protein YGL046W -0.03690305 0.902659634 -0.287164089 0.155841379 hypothetical protein YGL047W -0.30248372 0.23996829 -0.130461117 0.407979108 similarity to hypothetical S. pombe protein YGL048C -0.16040262 0.392995493 -0.022237716 0.583336728 RPT6 ATPase YGL049C 0.432592783 0.074189875 0.019021771 0.907487342 TIF4632 TIF4632 encodes one of two homologs of eIF-4G, the 150 kD subunit of the mRNA cap-binding complex (eIF-4F) YGL050W 0.54905542 0.134103804 -0.292802769 0.173980993 hypothetical protein YGL051W -0.74833533 0.06428939 0.083650815 0.003200356 strong similarity to YAR033w protein YGL052W -0.30844872 0.094896869 0.288725399 0.272137435 questionable ORF YGL053W -0.72048542 0.033503975 -0.028676307 0.852918505 PRM8 pheromone-regulated membrane protein YGL054C 0.517134743 0.087768549 0.118292159 0.092761693 ERV14 14 KDa protein found on ER-derived vesicles YGL055W -0.20913291 0.706080516 0.04957515 0.834894061 OLE1 delta-9-fatty acid desaturase YGL056C -0.30030476 0.452546539 0.362387915 0.01901641 SDS23 similar to S. pombe sds23 YGL057C -0.27740012 0.155291453 -0.152631667 0.087692454 hypothetical protein Ubiquitin conjugating (E2) enzyme. The C-terminal 23 residues are critical for sporulation and histone polyubiquitinating activity, but not UV YGL058W 0.422228156 0.17904814 -0.096317051 0.450715342 RAD6 repair or induced mutagenesis. YGL059W -0.58469298 0.057637601 -0.560703105 0.042805489 similarity to rat branched-chain alpha-ketoacid dehydrogenase kinase YGL060W -0.05920726 0.851614298 -0.070366847 0.384825544 strong similarity to hypothetical protein YBR216c YGL061C 0.364181927 0.579709178 -0.111388892 0.618439065 DUO1 Death Upon Overexpression YGL062W -0.94368676 0.052710305 0.224775993 0.079102301 PYC1 pyruvate carboxylase YGL063W -0.08995316 0.908828583 0.34289231 0.114529995 PUS2 pseudouridine synthase 2 YGL064C 0.966143598 0.111062866 -0.071048862 0.551264655 similarity to YLR276c and YKR024c YGL065C 0.153138657 0.498783111 0.194540378 0.04451345 ALG2 glycosyltransferase YGL066W 0.131246272 0.396625298 -0.38270757 0.047593799 hypothetical protein YGL067W 0.43892762 0.195518552 0.094491237 0.482650719 NPY1 NADH pyrophosphatase 1 YGL068W 0.313978984 0.435549849 -0.012554694 0.79479866 probable ribosomal protein L12 YGL069C 0.106482699 0.703924976 0.054463161 0.34811734 questionable ORF YGL070C 1.116852632 0.189837063 0.052740796 0.626671832 RPB9 RNA polymerase II subunit YGL072C 1.103573546 0.125218912 0.635600006 0.106745044 questionable ORF YGL073W 1.252385873 0.219140478 0.332803536 0.031277102 HSF1 heat shock transcription factor YGL074C -0.30718143 0.347306933 -0.125349521 0.53344274 questionable ORF YGL075C -0.68466798 0.006979492 -0.296253054 0.079843614 MPS2 nuclear envelope /ER protein involved in chromosomal segregation YGL076C 0.853779945 0.050831096 0.374890396 0.039602658 RPL7A Ribosomal protein L7A (L6A) (rp11) (YL8) YGL077C 0.956323203 0.375712258 0.615803604 0.113989589 HNM1 Transporter (permease) for choline and nitrogen mustard ; share homology with UGA4 YGL078C 1.07488983 0.04015872 -0.481601638 0.070984533 DBP3 ATP-dependent RNA helicase CA3 of the DEAD /DEAH box family YGL079W 0.008397519 0.906758903 -0.014002278 0.880162516 hypothetical protein YGL080W 0.466001621 0.13724433 0.051402941 0.330872796 strong similarity to C.elegans R07E5.13 protein YGL081W -0.99442083 0.005396706 -0.319591633 0.175927211 hypothetical protein YGL082W -0.1273414 0.575901664 -0.192203687 0.047533311 strong similarity to hypothetical protein YPL191c YGL083W 0.124437078 0.538383184 0.066190966 0.142477266 SCY1 similar to bovine rhodopsin kinase ; suppressor of GTPase mutation YGL084C 0.090158568 0.689051713 0.515508825 0.123471172 GUP1 putative glycerol transporter YGL085W -0.28281439 0.184839917 -0.381843356 0.001293259 weak similarity to Staphylococcus aureus nuclease (SNase) YGL087C 0.251117322 0.098040105 0.39669272 0.118258081 MMS2 Similar to ubiquitin conjugating protein family YGL088W 0.707766022 0.103384128 1.152593698 0.061444034 questionable ORF YGL089C -0.34576079 0.519925819 -0.415909805 0.333503958 MF(ALPHA alpha mating factor YGL090W -0.49450791 0.464532966 -0.465566001 0.155929099 LIF1 interacts with DNA ligase protein YGL091C 0.160556998 0.440578722 0.017527884 0.66391667 NBP35 35 kDa nucleotide binding protein YGL092W 0.255410029 0.60918357 0.46017248 0.065919579 NUP145 nuclear pore protein YGL093W 0.132478236 0.329267485 -0.445587357 0.122290432 SPC105 component of spindle pole YGL094C 0.503637398 0.245052978 0.108078828 0.025368829 PAN2 135-kDa protein that is subunit of poly(A) ribonuclease YGL095C -0.08249414 0.451879588 -0.404320941 0.041875659 VPS45 cytosolic and peripheral membrane protein YGL097W 0.632716056 0.226987512 -0.173170504 0.310555333 SRM1 pheromone response pathway suppressor YGL098W -0.08332336 0.358181713 -0.76073702 0.021488875 hypothetical protein YGL099W 0.700725366 0.133529528 -0.302832994 0.254891396 similarity to putative human GTP-binding protein MMR1 YGL100W 0.24386191 0.526233149 -0.012351059 0.930514823 SEH1 nuclear pore protein YGL101W 0.675243153 0.375045891 -0.414127736 0.059643728 strong similarity to hypothetical protein YBR242w YGL102C 1.384579126 0.082127598 0.248642613 0.112240025 questionable ORF YGL103W 2.029320192 0.097768807 0.135393296 0.213072135 RPL28 Ribosomal protein L28 (L29) (rp44) (YL24) YGL104C -0.65293459 0.002670883 -0.056859636 0.514252905 similarity to glucose transport proteins YGL105W 0.379770339 0.352275765 0.20411786 0.089906127 ARC1 G4 nucleic acid binding protein, involved in tRNA aminoacylation YGL106W 0.325016379 0.346889341 -0.182859324 0.203631084 MLC1 light chain for myosin Myo2p YGL107C 0.500452629 0.169490244 -0.385621604 0.014299586 strong similarity to hypothetical protein YBR238c YGL108C -0.18949647 0.270586792 -0.343513377 0.244160001 weak similarity to hypotetical S.pombe protein YGL109W 0.282506147 0.472401654 -0.114676903 0.657936797 questionable ORF YGL110C 0.169077698 0.613154556 -0.257667038 0.034688876 hypothetical protein YGL111W 0.789659045 0.000572338 -0.404699255 0.073455473 hypothetical protein YGL112C -0.18903288 0.324602598 -0.070004724 0.648055959 TAF60 TATA-binding protein-associated-factor YGL113W 0.104623483 0.735028447 -0.277631914 0.060139078 weak similarity to YOR165w YGL114W -0.49856338 0.110878661 0.121706458 0.138576095 weak similarity to H.influenzae permease YGL115W -0.09334834 0.480114245 -0.259705553 0.052451546 SNF4 associates with Snf1p YGL116W 0.363136699 0.190192325 -0.153203096 0.621491425 CDC20 anaphase promoting complex subunit YGL117W 0.131148796 0.730804533 -0.718974035 0.039895529 hypothetical protein YGL118C -0.45114526 0.377711313 0.020345268 0.422649731 questionable ORF YGL119W -0.10690078 0.653821389 -0.197465981 0.011042553 ABC1 ubiquinol-cytochrome-c reductase assembly protein YGL120C 1.859252663 0.245463236 0.097887572 0.217476251 PRP43 RNA helicase YGL121C -0.95690157 0.098832943 -0.093309901 0.776174583 hypothetical protein YGL122C -0.13896144 0.374075584 -0.324686471 0.502470201 NAB2 nuclear polyadenylated RNA binding protein YGL123W 1.47580959 0.176326389 0.298163085 0.176786808 RPS2 Ribosomal protein S2 (S4) (rp12) (YS5) YGL124C -0.13329573 0.445543705 -0.16067816 0.11934161 MON1 hypothetical protein YGL125W -0.92545748 0.033421869 0.419972862 0.007721024 MET13 putative methylenetetrahydrofolate reductase (mthfr) YGL126W 0.063614329 0.866948488 0.343348611 0.32290246 SCS3 involved in inositol biosynthesis SOH1 encodes a novel 14-kD protein with limited sequence similarity to RNA polymerases. The Soh1 protein interacts with a DNA repair YGL127C 0.875929887 0.06749458 0.60377419 0.032963762 SOH1 protein, Rad5p, in a two-hybrid system assay. YGL128C -0.17259403 0.571612805 0.513061144 0.135789177 putative heat shock protein protein YGL129C 0.754404065 0.160306671 -0.202149229 0.030918943 RSM23 protein of the small subunit of the mitochondrial ribosome YGL130W -0.05137306 0.835022688 0.136658837 0.150155169 CEG1 mRNA guanylyltransferase (mRNA capping enzyme), alpha subunit YGL131C 0.233210147 0.374967233 -0.136169705 0.368304751 weak similarity to S.pombe hypothetical protein C3H1.12C YGL132W -0.08661443 0.349200476 0.437994676 0.127781706 questionable ORF YGL133W 0.267649292 0.069662771 0.617390842 0.085479281 ITC1 A subunit of Isw2 chromatin remodeling complex YGL134W -0.04444229 0.864079782 -0.246242782 0.233974627 PCL10 PHO85 cyclin YGL135W 1.595980048 0.008230744 0.465602625 0.017986272 RPL1B Ribosomal protein L1B YGL136C -0.66747033 0.02022567 0.025673862 0.657834654 weak similarity to E.coli ftsJ protein YGL137W -0.03974449 0.811895779 0.075362968 0.580767343 SEC27 encodes beta'-subunit of yeast coatomer YGL138C 0.372987806 0.60529681 0 #DIV/0! hypothetical protein YGL139W -0.14516081 0.214493651 0.302385829 0.141466956 strong similarity to hypothetical protein YPL221w YGL141W -0.29257507 0.349306609 -0.010455181 0.857797264 HUL5 ubiquitin-protein ligase (E3) Protein involved in Glycosyl Phosphatidyl Inositol synthesis ; could be the target of the GPI synthesis inhibitor, YW3548 ; Most likely an alpha YGL142C -0.09967989 0.744736846 0.223435116 0.287557709 GPI10 1,2 mannosyltransferase utilized for the addition of the third mannose onto the GPI core structure. YGL143C -0.02431993 0.914976709 -0.089771274 0.237038952 MRF1 Mitochondrial polypeptide chain release factor YGL144C -0.24152822 0.204038486 -0.384395873 0.001917885 lipase motif protein YGL145W 0.277766316 0.279651477 -0.470795257 0.02617348 TIP20 transport protein that interacts with Sec20p ; required for protein transport from the endoplasmic reticulum to the golgi apparatus YGL146C -1.17811737 0.024785445 -0.182462631 0.249289185 YGL147C 2.001154361 0.033862605 0.058206669 0.780159902 RPL9A Ribosomal protein L9A (L8A) (rp24) (YL11) YGL148W 0.448194368 0.376741146 0.195972141 0.235833808 ARO2 Chorismate synthase YGL149W 0.382276386 0.25670559 0.07827197 0.598124175 questionable ORF YGL150C -0.28871956 0.509506774 -0.315092928 0.016333488 INO80 similar to the Snf2p family of DNA-dependent ATPases YGL151W 0.453857649 0.054071017 0.222917955 0.188577193 NUT1 negative regulator of HO endonuclease YGL152C 0.023306898 0.930670482 -0.408467439 0.026556497 questionable ORF YGL153W -0.16526837 0.540064072 -0.469806494 0.045028856 PEX14 component of peroxisomal import machinery YGL154C -0.01411467 0.928333067 0.052991773 0.103649764 LYS5 aminoadipate-semialdehyde dehydrogenase small subunit (alpha-aminoadipate reductase) YGL155W 0.300538956 0.309032047 0.045510046 0.146922147 CDC43 polypeptide subunit of a yeast type 1 protein geranylgeranyltransferase YGL156W -2.31282008 0.000181206 0.142521199 0.588891781 AMS1 vacuolar alpha mannosidase YGL157W 2.90742189 0.394227137 0.043815062 0.573304799 similarity to V.vinifera dihydroflavonol 4-reductase YGL158W 0.205862729 0.632327364 -0.387416151 0.293363412 RCK1 Serine /threonine protein kinase YGL159W -0.40804121 0.09505632 -0.638616347 0.010498556 hypothetical protein YGL160W 0.168518041 0.171444684 0.436463219 0.101241908 similarity to hypothetical protein YLR047c and Fre2p YGL161C -0.26822895 0.256712676 0.424038632 0.102680943 hypothetical protein YGL162W 1.054924502 0.238637038 0.257809924 0.202059382 SUT1 hypoxic gene family involved in sterol transport YGL163C -0.0550967 0.861742602 -0.265856802 0.098405149 RAD54 DNA-dependent ATPase YGL164C -0.28357214 0.114066025 -0.671138546 0.044378772 similarity to S.pombe hypothetical protein SPAC31A2.10 YGL165C 0.114871513 0.817770519 0.190257943 0.260311502 questionable ORF YGL166W 0.161380771 0.833718462 0.083848498 0.43081407 CUP2 Activator of transcription YGL167C -0.01838558 0.946968064 0.431733104 0.079501728 PMR1 Ca++-Pump, ATPase YGL168W 0.230471695 0.159267188 0.834712514 0.101908754 questionable ORF YGL169W 0.613083452 0.017629446 -0.18011771 0.000409411 SUA5 translation initiation protein YGL170C 0.514102543 0.251371652 0.36598755 0.057082686 hypothetical protein YGL171W 0.953424893 0.188663314 -0.478425916 0.153503257 ROK1 RNA helicase involved in rRNA processing YGL172W -0.12754819 0.352385111 -0.052281782 0.534160772 NUP49 nuclear pore complex protein with GLFG repetitive sequence motif YGL173C -0.43720818 0.18897 0.342232078 0.116316616 KEM1 cytoplasmic 5'-to-3' exonuclease. YGL174W -0.20769256 0.284462204 -0.365358444 0.046247944 weak similarity to C.elegans hypothetical protein R08D7.1 YGL175C 0.138511723 0.633758119 -0.133916559 0.621780092 SAE2 involved in meiotic recombination YGL176C -0.46961448 0.027277749 -0.322066629 0.075164406 weak similarity to Oryctolagus calcium channel BIII YGL177W -0.05426997 0.742876826 0.940841874 0.032251433 questionable ORF YGL178W 0.459761635 0.247683167 0.478231101 0.146015708 MPT5 multicopy suppressor of POP2 YGL179C 0.00729222 0.989782315 -0.001898794 0.978482578 TOS3 strong similarity to Pak1p, Elm1p and Kin82p YGL180W -0.85148324 0.051160586 -0.102695347 0.140157579 APG1 Protein kinase YGL181W -0.09075206 0.630931348 -0.170865483 0.002287436 GTS1 Glycine-threonine-serine repeat protein YGL182C 0.540674806 0.603127628 -0.23176122 0.422649731 questionable ORF YGL183C -0.20728313 0.641737148 0.050083012 0.677598746 hypothetical protein YGL184C -0.43313751 0.321914961 -0.036811149 0.677227 STR3 Cystathionine beta-lyase YGL185C -0.66868024 0.010109949 -0.351887424 0.077007399 weak similarity to dehydrogenases YGL186C 0.393512661 0.264912822 0.166510348 0.395623681 similarity to hypothetical protein Fcy21p and weak similarity to FCY2 protein YGL187C -2.12848189 0.000904118 -0.041084238 0.726324551 COX4 subunit IV of cytochrome c oxidase YGL188C -1.90555513 0.000537189 -0.024188529 0.857446312 hypothetical protein YGL189C 1.432802172 0.091822196 0.132248912 0.42787916 RPS26A Ribosomal protein S26A YGL190C -0.05600597 0.344141063 -0.320595262 0.061911212 CDC55 Protein phosphatase 2A regulatory subunit B YGL191W -1.12369695 0.000356155 0.335233415 0.181787904 COX13 subunit VIa of cytochrome c oxidase, may specifically interact with ATP YGL192W -0.28568762 0.26727716 0.426904957 0.369673071 IME4 mRNA methyltransferase (putative) YGL193C 0.162150706 0.583308744 0.746796671 0.092719427 questionable ORF YGL194C -0.77085317 0.000572336 0.046422212 0.015802607 HOS2 (putative) histone deacetylase YGL196W -0.77695372 0.047074099 0.234606343 0.397576705 hypothetical protein YGL197W -0.70665777 0.070068174 0.435114604 0.121276979 MDS3 negative regulator of early meiotic genes YGL198W 0.557686765 0.019807361 0.493214052 0.090186651 weak similarity to Yip1p YGL199C 0.277107277 0.16090635 0.558237324 0.065061788 questionable ORF YGL200C 0.636164764 0.139842544 0.597813087 0.127997314 EMP24 type I transmemebrane protein, component of COPII-coated, ER-derived transport vesicles YGL201C -0.19118208 0.623168499 -0.160702852 0.196123654 MCM6 component of MCM initiator complex involved in DNA replication YGL202W 0.450576609 0.501598384 0.156572998 0.31450457 ARO8 aromatic amino acid aminotransferase YGL203C 0.330737478 0.282331718 -0.330401424 0.085909422 KEX1 carboxypeptidase B-like processing protease YGL204C 0.383818363 0.495367672 0.428401874 0.164701702 questionable ORF YGL205W -0.26466305 0.609196084 0.911819568 0.03593723 POX1 fatty-acyl coenzyme A oxidase YGL206C -0.41959845 0.007786152 0.324727729 0.050273862 CHC1 presumed vesicle coat protein YGL207W -0.09943549 0.4864863 0.142836209 0.252399472 SPT16 global regulator of transcription YGL208W -1.11167837 0.016789153 0.09699025 0.402275506 SIP2 component of Snf1 protein complex involved in response to glucose starvation YGL209W 0.987149006 0.365232572 0.580200231 0.198543001 MIG2 Protein containing zinc fingers very similar to zinc fingers in Mig1p YGL210W 0.286617211 0.626948958 -0.198568692 0.050757891 YPT32 ras-like GTPase, highly homologous to YPT31 YGL211W -0.19284332 0.36472606 -0.149051355 0.22932606 similarity to M.jannaschii hypothetical proteins MJ1157 and MJ1478 YGL212W -0.05001913 0.857947861 0.202600963 0.38126868 VAM7 hydrophilic protein, heptad repeat motif YGL213C 0.319269212 0.151488985 0.20307174 0.289008161 SKI8 antiviral protein, mRNA is induced early in meiosis YGL214W 0.433521147 0.09596751 0.319516711 0.104771772 questionable ORF YGL215W 0.091023462 0.75935305 0.567934132 0.054206234 CLG1 cyclin-like protein that interacts with Pho85 YGL216W -0.5002086 0.180704502 0.292824027 0.097022977 KIP3 kinesin-related protein involved in mitosis YGL217C 0.324206129 0.510578309 0.337497231 0.682781151 questionable ORF YGL218W -0.18909055 0.478293101 0.114277359 0.53930527 questionable ORF YGL219C -0.07101328 0.790965459 0.210020666 0.204989015 hypothetical protein YGL220W 0.78932595 0.104261059 0.571967273 0.014117691 weak similarity to V.alginolyticus bolA protein YGL221C 0.176409565 0.286446727 0.33918449 0.074073041 NIF3 similar to Listeria monocytogenes major sigma factor (rpoD gene product) YGL222C -0.35981681 0.200988633 0.589760092 0.01052929 EDC1 Enhancer of mRNA Decapping YGL223C 0.109690854 0.559476753 0.052899524 0.465122882 weak similarity to Clostridium regulatory protein YGL224C -0.37970735 0.332312141 0.140372025 0.218673939 strong similarity to hypothetical protein YER037w YGL225W 1.419550177 0.283781864 0.864306102 0.034894397 GOG5 Golgi GDP-mannose transporter YGL226C-A 0.447221888 0.277250458 0.840126566 0.016459088 OST5 9.5-kDa zeta subunit of oligosaccharyltransferase complex YGL226W 0.487271756 0.092753289 0.015296821 0.884261639 similarity to N.crassa cytochrome-c oxidase chain V YGL227W -0.6580472 0.118456637 0.082239146 0.270458359 VID30 TOR inhibitory protein, similar to Dictyostelium discoideum non-receptor tyrosine kinase YGL228W -0.41124834 0.104145422 -0.096850994 0.218564785 SHE10 lethal when overexpressed YGL229C -0.35423244 0.318330517 0.02482893 0.751302684 SAP4 Sit4 protein phosphatase-associated protein YGL230C 1.112835356 0.057584538 0.058964675 0.61970254 hypothetical protein YGL231C 1.063273076 0.130839074 0.147194849 0.004921146 hypothetical protein YGL232W 0.49811141 0.186570941 -0.649107203 0.116417924 weak similarity to P.falciparum dihydropteroate synthase 113kD component of the Exocyst complex, which contains the gene products encoded by SEC3, SEC5, SEC6, SEC8, SEC10, SEC15 and YGL233W -0.59412919 0.080123832 -0.236989966 0.021061359 SEC15 EXO70. YGL234W 0.70135199 0.070214392 -0.05372842 0.536088159 ADE5,7 glycinamide ribotide synthetase and aminoimidazole ribotide synthetase YGL235W -0.76204898 0.049406933 -0.018575861 0.941151927 questionable ORF YGL236C 0.525203832 0.31783073 0.09179018 0.598875447 MTO1 Mitochondrial Translation Optimization ; Strong similarity to E. coli GidA YGL237C -0.77148263 0.000578582 -0.051285166 0.436566901 HAP2 transcriptional activator protein of CYC1 YGL238W 0.218266262 0.103160953 -0.148982993 0.087019469 CSE1 (putative) kinetochore protein YGL239C 0.226707873 0.523744232 0.366954975 0.142705873 questionable ORF YGL240W 0.286700534 0.022360976 -0.062555671 0.736138121 DOC1 component of the anaphase-promoting complex YGL241W -0.13322021 0.464982646 -0.210115684 0.098493339 KAP114 Kap114p YGL242C 0.707754296 0.204973508 -0.107058829 0.438673486 weak similarity to Drosophila ANK protein YGL243W -0.47710782 0.01719815 -0.545114086 0.005808255 TAD1 tRNA-specific adenosine deaminase 1 (TAD1) ; Tad1p /scADAT1 YGL244W -0.38173696 0.028258051 -1.097002938 0.022747178 RTF1 Nuclear protein YGL245W -0.01233866 0.95249199 0.065741226 0.577600462 strong similarity to glutamine--tRNA ligase YGL246C 0.478994241 0.240459172 -0.597228331 0.055615874 RAI1 weak similarity to C.elegans dom-3 protein YGL247W -0.13115753 0.44103792 -0.098504003 0.309583504 similarity to hypothetical protein YHR036w YGL248W -0.40124954 0.205574585 0.037061082 0.510974687 PDE1 3',5'-Cyclic-nucleotide phosphodiesterase, low affinity YGL249W 0.589035102 0.166576336 -0.146933495 0.021825343 ZIP2 involved in meiotic recombination and disjunction YGL250W -1.84237827 0.000198569 -0.181752397 0.198187542 hypothetical protein YGL251C -0.55976518 0.029869141 0.013305024 0.84517926 HFM1 C4 zinc finger DNA-binding protein of low sequence specificity in vitro ; Probable 119 kD DNA /RNA helicase family member YGL252C 0.085172945 0.799727513 -0.011160266 0.95698642 RTG2 involved in interorganelle communication between mitochondria, peroxisomes, and nucleus YGL253W 2.377755953 0.365431351 0.575674758 0.018378815 HXK2 Hexokinase II (PII) (also called Hexokinase B) YGL254W 0.171213311 0.594438581 0.239087007 0.169256791 FZF1 putative transcription factor, has five zinc fingers YGL255W 0.807265295 0.397085617 0.492144494 0.120106197 ZRT1 high-affinity zinc transport protein YGL256W -2.24369104 0.009676821 -0.360301639 0.495327114 ADH4 alcohol dehydrogenase isoenzyme IV YGL257C -1.28528995 0.003161946 -0.565775543 0.029815752 MNT2 alpha-1,3-mannosyltransferase YGL258W -1.73291698 0.049095843 -0.110647823 0.897585072 strong similarity to hypothetical protein YOR387c YGL259W -0.65601746 0.094369404 0.014709638 0.956171394 YPS5 GPI-anchored aspartic protease YGL260W 0.124327612 0.85638779 0.088368207 0.638670818 strong similarity to subtelomeric encoded proteins YGL261C 0.005511888 0.985337126 0.772303392 0.062414755 strong similarity to members of the Srp1/Tip1 family YGL262W -0.7967933 0.025308075 -0.228194689 0.203168884 similarity to hypothetical protein YER187w YGL263W 0.564158745 0.215240041 -0.307995906 0.058630212 COS12 similar to subtelomerically-encoded proteins YGR001C 0.164722539 0.067096551 0.015277053 0.940339242 similarity to C.elegans hypothetical M142.5 protein YGR002C 0.524441255 0.068492369 -0.193212726 0.434800883 similarity to hypothetical S. pombe protein YGR003W 0.094740009 0.691839707 -0.181315874 0.092971762 similarity to D.melanogaster lin19 protein YGR004W 0.323143645 0.280735274 0.429807698 0.133262058 similarity to D.melanogaster lin19 protein YGR005C 0.036693205 0.843487408 -0.491809565 0.146098403 TFG2 transcription initiation factor TFIIF middle subunit YGR006W 0.507152152 0.25206873 -0.136668467 0.582102295 PRP18 RNA splicing factor associated with U5 snRNP YGR007W 0.44393268 0.222512347 -0.022648106 0.70254583 MUQ1 choline phosphate cytidylyltransferase (also called phosphoethanolamine cytidylyltransferase or phosphocholine cytidylyltransferase) YGR008C -1.01470663 0.051418897 -0.197125042 0.001167427 STF2 ATPase stabilizing factor YGR009C 0.038341336 0.848316758 -0.825546473 0.007410352 SEC9 Putative t-SNARE of the plasma membrane YGR010W -0.71223813 0.005863035 0.012615307 0.541541905 strong similarity to hypothetical protein YLR328w YGR011W -0.19649837 0.374559057 0.142500466 0.067326642 questionable ORF YGR012W -0.54326712 0.034929276 -0.344597877 0.010822852 similarity to E.nidulans cysteine synthase YGR013W 0.181146334 0.494446321 -0.211743161 0.22148502 SNU71 U1 snRNP protein YGR015C -0.46223676 0.207235046 -0.318941558 0.424436751 similarity to hypothetical protein YGR031w YGR016W -0.49580565 0.103619994 -0.334365864 0.012203843 weak similarity to M.jannaschii hypothetical protein MJ1317 YGR017W 0.602400461 0.038670848 -0.244909512 0.230469598 hypothetical protein YGR018C 0.646473886 0.00961816 0.172238333 0.31387684 questionable ORF YGR019W -0.43665655 0.245949696 0.138705989 0.600288835 UGA1 gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) YGR020C 0.305178321 0.530965888 0.27801036 0.259026695 VMA7 vacuolar ATPase V1 domain subunit F (14 kDa) YGR021W 0.494341966 0.309896209 -0.351941122 0.081236084 similarity to M.leprae yfcA protein YGR022C -0.16004148 0.671189916 0.394574525 0.060587102 questionable ORF YGR023W -0.11691183 0.725749341 0.910019239 0.033393898 MTL1 acts in concert with Mid2p to transduce cell wall stress signals YGR024C -0.32385635 0.299003363 -0.746112165 0.025865969 weak similarity to Methanobacterium thermoautotrophicum hypothetical protein MTH972 YGR025W -0.45221147 0.014027775 0.365491134 0.109933375 questionable ORF YGR026W -0.16743778 0.197958996 0.365191244 0.169898848 hypothetical protein YGR027C 0.639048422 0.02798567 0.129112644 0.028986798 RPS25A Ribosomal protein S25A (S31A) (rp45) (YS23) YGR027W-A 1.116779505 0.186552291 0.4877318 0.035847754 TyA gag protein. Gag processing produces capsid proteins. YGR028W -1.07683601 0.017641432 -0.391276985 0.014663753 MSP1 40 kDa putative membrane-spanning ATPase YGR029W 0.40142303 0.111424691 -0.18962391 0.04636784 ERV1 involved in mitochondrial biogenesis YGR030C 0.146790183 0.230705774 -0.415481504 0.194509083 POP6 integral subunit of RNase P and apparent subunit of RNase MRP YGR031W -0.91655707 0.00379962 0.100741504 0.163524246 similarity to hypothetical protein YGR015c and weak similarity H.influenzae dihydrolipoamide acetyltransferase YGR033C -0.31872457 0.012514194 -0.452631189 0.063770704 hypothetical protein YGR034W 1.397907971 0.129421428 0.291451143 0.147152203 RPL26B Ribosomal protein L26B (L33B) (YL33) YGR035C 0.506823275 0.135333807 0.137500063 0.664263479 hypothetical protein CAX4p contains 3 short stretches of amino acids that are characteristic for a wide variety of phosphatases, including lipid phosphatases and a YGR036C 1.377245936 0.310576632 0.180666336 0.073962728 CAX4 protein phosphatase. YGR037C 0.412954866 0.521214523 0.526935257 0.132902697 ACB1 Acyl-CoA-binding protein (ACBP) /Diazepam binding inhibitor (DBI) /endozepine (EP) YGR038C-A 1.142473873 0.077625447 0.51053945 0.017047251 TyA gag protein. Gag processing produces capsid proteins. YGR038W 0.144220723 0.4012412 0.729151434 0.064907233 ORM1 strong similarity to hypothetical protein YLR350w YGR039W 1.255368845 0.099054447 0.776559467 0.025394302 questionable ORF YGR040W 1.337129245 0.147829101 0.166593643 0.09144382 KSS1 MAP protein kinase homolog involved in pheromone signal transduction YGR041W -0.63903023 0.025254456 0.540272815 0.156819622 BUD9 involved in bud-site selection YGR042W -0.7414906 0.005421941 -0.371114037 0.211364333 hypothetical protein YGR043C -1.72886464 0.019325214 -0.400689051 0.067722441 strong similarity to transaldolase YGR044C -0.74806306 0.176829418 -0.006560591 0.961670618 RME1 zinc finger protein ; negative regulator of meiosis ; directly repressed by a1-a2 regulator YGR045C -0.10089851 0.593765198 0.212178926 0.237213557 questionable ORF YGR046W -0.08776282 0.742478469 -0.144031918 0.147393663 hypothetical protein YGR047C -0.05887125 0.636722003 -0.326309628 0.027238301 TFC4 transcription factor tau (TFIIIC) subunit 131 YGR048W 0.140467095 0.720372868 -0.008489511 0.925046453 UFD1 ubiquitin fusion degradation protein YGR049W 0.821619998 0.178732698 0.469578092 0.070840113 SCM4 suppressor of cdc4 mutations YGR050C -0.80781769 0.003607189 0.270039648 0.404712252 questionable ORF YGR051C -0.55421403 0.039762777 -0.246925763 0.216126441 questionable ORF YGR052W -3.16303919 0.00022605 -0.221523834 0.298897231 similarity to ser/thr protein kinases YGR053C -1.9161916 0.000450867 -0.869462482 0.003866847 hypothetical protein YGR055W -0.23847659 0.3693832 0.53722241 0.062011041 MUP1 high affinity methionine permease YGR056W 0.056603261 0.771842906 -0.041137301 0.272529306 RSC1 Member of RSC complex YGR057C -0.06966855 0.800248811 -0.740502572 0.014803947 LST7 involved in transport of nitrogen-regulated permeases YGR058W -0.26482908 0.039585293 0.042096472 0.685715936 similarity to mouse calcium-binding protein YGR059W -0.73988645 0.024829185 0 #DIV/0! SPR3 septin protein involved in sporulation YGR060W 0.029051137 0.92886288 0.369947256 0.205291632 ERG25 C-4 sterol methyl oxidase YGR061C -0.05770667 0.810893013 -0.127641844 0.223239159 ADE6 5'-phosphoribosylformyl glycinamidine synthetase YGR062C -0.06584873 0.363089176 0.102654669 0.460999992 COX18 required for mitochondrial cytochrome oxidase activity YGR063C 0.884398821 0.114999203 0.557578285 0.09105786 SPT4 Zn-finger protein, transcriptional regulator YGR064W 0.86781237 0.140649607 0.501445222 0.17888786 questionable ORF YGR065C 0.022263949 0.93165123 0.621454017 0.0721802 VHT1 H+-biotin symporter YGR066C -1.89594281 0.00022269 -0.188528693 0.622240023 similarity to hypothetical protein YBR105c YGR067C -1.05778693 0.127313154 0.147902489 0.34145805 weak similarity to transcription factors YGR068C -0.50847474 0.214545559 0.10134827 0.213892247 weak similarity to Rod1p YGR069W 1.411427005 0.102835149 0.58466646 0.303992382 questionable ORF YGR070W -0.69190985 0.054737961 -0.0150259 0.726873264 ROM1 Rho1 GDP /GTP exchange protein YGR071C 0.043580385 0.768444043 -0.500476196 0.049291136 similarity to hypothetical protein YLR373c YGR072W -0.07631209 0.52210071 -0.955776753 0.042067768 UPF3 involved in decay of mRNA containing nonsense codons YGR073C 0.273629275 0.428406649 0.401764978 0.003991274 questionable ORF YGR074W 0.47627433 0.192950269 0.33105209 0.042600931 SMD1 U6 snRNP protein YGR075C 0.311130245 0.064807613 0.117930479 0.370033951 PRP38 RNA splicing factor YGR076C 0.433978151 0.062314547 -0.37425857 0.157123185 MRPL25 Mitochondrial ribosomal protein MRPL25 (YmL25) YGR077C -0.34172938 0.235476017 0.331955356 0.086124141 PEX8 peroxisome associated protein containing a PTS1 signal YGR078C 0.28272047 0.340402808 0.377506166 0.25608899 PAC10 Polypeptide 3 of a Yeast Non-native Actin Binding Complex, homolog of a component of the bovine NABC complex YGR079W 0.88173678 0.283589032 0.180497129 0.255419334 hypothetical protein YGR081C 1.002901892 0.043669575 -0.735966878 0.075630956 weak similarity to mammalian myosin heavy chain YGR082W 1.108355355 0.001741568 0.346078362 0.125164144 TOM20 20 kDa mitochondrial outer membrane protein import receptor YGR083C 0.318390601 0.113107308 -0.284928327 0.197759362 GCD2 translation initiation factor eIF2B, 71 kDa (delta) subunit ; translational repressor of GCN4 protein YGR084C 0.280623417 0.160345172 -0.189396595 0.331992017 MRP13 35 kDa mitochondrial ribosomal small subunit protein YGR085C 1.143842256 0.033554383 0.055413968 0.803008706 RPL11B 60S ribosomal protein L11B (L16B) (rp39B) (YL22) YGR086C -0.81521255 0.022525733 0.025316352 0.836144577 strong similarity to hypothetical protein YPL004c YGR087C -0.17406522 0.819416947 0.784909256 0.068347413 PDC6 Third, minor isozyme of pyruvate decarboxylase YGR088W -3.31111885 0.000318882 0.050016287 0.583860999 CTT1 cytoplasmic catalase T YGR089W 0.824416004 0.091945158 0.421871492 0.037461971 weak similarity to rat tropomyosin YGR090W 1.729811443 0.119978147 0.508210015 0.080224615 hypothetical protein YGR091W -0.3976683 0.075633846 -0.151535252 0.243885531 PRP31 pre-mRNA splicing protein YGR092W 0.218656276 0.556901292 -0.218460214 0.040296064 DBF2 Serine /threonine protein kinase YGR093W -0.10699224 0.466453575 -0.362161823 0.073182067 similarity to hypothetical S.pombe protein YGR094W 0.757183407 0.067390758 -0.022458302 0.701580861 VAS1 mitochondrial and cytoplasmic valyl-tRNA synthetase YGR095C 0.405388253 0.178301128 -0.169741722 0.368974372 RRP46 Putative 3'->5' exoribonuclease ; component of exosome complex of 3'->5' exonucleases YGR096W 0.603261859 0.041423443 0.269048897 0.019558938 similarity to bovine Graves disease carrier protein YGR097W 0.485585 0.034909839 0.324735043 0.086368807 ASK10 transcriptional activator of the SKN7 mediated 'two-component' regulatory system YGR098C -0.08206393 0.711717985 0.226083945 0.009570962 ESP1 involved in regulation of spindle pole body duplication YGR099W -0.52246294 0.059208656 -0.396904735 0.012825266 TEL2 telomere binding protein YGR100W -0.27145031 0.120434755 -0.247174038 0.018025748 MDR1 interacts with Mac1, a transcription factor that regulates genes involved in copper and iron utilization YGR101W -0.05837415 0.732234512 0.341037869 0.332916002 weak similarity to B.subtilis YqgP YGR102C -0.40681773 0.138260633 -0.036530678 0.901909434 hypothetical protein YGR103W 0.679743831 0.168238312 -0.42613317 0.197641921 similarity to zebrafish essential for embryonic development gene pescadillo YGR104C 0.501994511 0.104550225 -0.16866311 0.229039467 SRB5 subunit of RNA polymerase II holoenzyme /mediator complex YGR105W 0.187796072 0.515565298 0.027382489 0.78295841 VMA21 vacuolar H+-ATPase assembly protein YGR106C 0.138623243 0.689860033 0.293843887 0.043079301 hypothetical protein YGR107W -0.64482083 0.17557976 0.478229411 0.240642274 questionable ORF YGR108W 0.372496881 0.752231415 -0.13342706 0.144320836 CLB1 G(sub)2-specific B-type cyclin YGR109C -0.55894205 0.224045765 0.548437103 0.002667461 CLB6 B-type cyclin YGR109W-A -0.78806192 0.005094078 -0.250404017 0.568367406 Ty3A gag protein. Gag processing produces capsid proteins. YGR110W -1.02060027 0.035275985 -0.182841436 0.215250911 weak similarity to YLR099c and YDR125c YGR111W -0.74292626 0.019071716 -0.308823539 0.066745443 weak similarity to mosquito carboxylesterase YGR112W -0.31071148 0.306723484 -0.346999028 0.031284813 SHY1 mitochondrial protein with homology to the mammalian SURF-1 gene YGR113W -0.19552776 0.159803705 -0.097428379 0.177515551 DAM1 spindle pole body protein YGR114C -0.00016231 0.9993667 0.082192883 0.461461171 questionable ORF YGR115C -0.36570866 0.109866244 -0.384435828 0.171014228 questionable ORF YGR116W 0.379368052 0.079021089 -0.437845055 0.08642645 SPT6 transcriptional regulator, interacts with histones, primarily histone H3, possesses nucleosome assembly activity YGR117C 1.339202661 0.057462384 0.17748875 0.516283023 hypothetical protein YGR118W 1.905998532 0.143971105 -0.055413475 0.723544445 RPS23A Ribosomal protein S23A (S28A) (rp37) (YS14) YGR119C 0.714709436 0.06492075 -0.781664385 0.132510056 NUP57 Contains GLFG repeats in N-terminal half and heptad repeats in C-terminal half YGR120C 0.119706897 0.452851002 -0.478293265 0.056896756 SEC35 peripheral membrane protein involved in secretion YGR121C -1.2205737 0.047035435 0.326477707 0.183889787 MEP1 ammonia permease YGR122C-A 0.185582322 0.306698835 0.241219307 0.156540636 questionable ORF - identified by SAGE YGR122W -0.98955886 0.001393801 -0.400832807 0.063127385 hypothetical protein YGR123C 0.942247017 0.192314227 -0.042150916 0.66204098 PPT1 serine /threonine phosphatase YGR124W 1.032332679 0.124128431 0.113767664 0.10422262 ASN2 asparagine synthetase YGR125W -0.07892454 0.901536035 0.317545307 0.300789337 similarity to S.pombe hypothetical protein SPAC24H6.11c YGR126W -0.32410413 0.369329406 0.196778778 0.261673655 weak similarity to hypothetical protein YPR156c YGR127W -0.35089241 0.031912412 -0.017130201 0.89642087 weak similarity to mouse T10 protein YGR128C 1.225414626 0.057221041 -0.184765722 0.272680824 hypothetical protein YGR129W 0.049035464 0.763774974 -0.541401809 0.039423444 SYF2 (putative) involved in pre-mRNA splicing YGR130C -0.83756723 0.03127352 -0.196822231 0.002863839 weak similarity to myosin heavy chain proteins YGR131W 0.812310036 0.08211439 0.328423819 0.009556425 strong similarity to Nce2p YGR132C 0.00112033 0.997579541 -0.288946702 0.108535619 PHB1 mitochondrial protein, prohibitin homolog ; similar to S. cerevisiae Phb2p YGR133W -0.47183916 0.095073927 0.365912418 0.134291324 PEX4 Member of ubiquitin-conjugating protein family YGR134W 0.197393158 0.207915635 -0.062886809 0.36375383 CAF130 CCR4 associated factor 130 kDa YGR135W 0.034141025 0.915661881 -0.443858981 0.023393449 PRE9 proteasome component Y13 YGR136W 0.634386755 0.216750544 0.171343481 0.179006452 weak similarity to chicken growth factor receptor-binding protein GRB2 homolog YGR137W 0.860243269 0.250439989 0.341507668 0.003216456 questionable ORF YGR138C -1.0342082 0.058641067 -0.085576597 0.74073522 similarity to multidrug resistance proteins YGR139W -0.11674957 0.186642433 0.671648685 0.09331819 questionable ORF YGR140W 0.653918314 0.213847035 0.129070448 0.546113959 CBF2 110 kDa subunit of the centromere binding factor CBF3 YGR141W -0.68650758 0.079241239 0.047476563 0.64291758 strong similarity to hypothetical protein YPR157w YGR142W -0.91113225 0.05186615 -0.427149946 0.093256888 BTN2 Gene /protein whose expression is elevated in a btn1 minus /Btn1p lacking yeast strain. YGR143W -1.25673543 0.000950023 0.407984106 0.095022684 SKN1 encodes a predicted type II membrane protein highly homologous to Kre6p YGR144W 2.213715142 0.184984559 0.752889325 0.145215223 THI4 component of the biosynthetic pathway producing the thiazole precursor of thiamine YGR145W -0.52241609 0.203936523 -0.758246722 0.05226602 similarity to C.elegans hypothetical protein YGR146C -0.4756977 0.057670868 0.516174001 0.024474063 hypothetical protein YGR147C 0.390202008 0.206870432 0.139743429 0.325395549 NAT2 N alpha-acetyltransferase that acts on methionine termini YGR148C 0.818354508 0.047120709 -0.16705702 0.555549897 RPL24B Ribosomal protein L24B (rp29) (YL21) (L30B) YGR149W 0.339577565 0.66053139 0.501806772 0.121723002 hypothetical protein YGR150C 0.573433644 0.067520116 -0.799897284 0.003071718 hypothetical protein YGR151C 1.328706533 0.224236822 -0.510682288 0.090083812 questionable ORF YGR152C 1.598803546 0.265637286 -0.613032295 0.11000592 RSR1 GTP-binding protein, ras superfamily YGR153W 1.398172773 0.125766022 -0.086719301 0.686438744 TOS10 hypothetical protein YGR154C -0.15598049 0.692721709 0.088528521 0.383706201 strong similarity to hypothetical proteins YKR076w and YMR251w YGR155W 0.096115731 0.737789494 0.432116099 0.106243576 CYS4 Cystathionine beta-synthase YGR156W 0.588154464 0.031624826 0.63450009 0.000432366 hypothetical protein YGR157W -0.1495812 0.683355196 0.24119096 0.043166849 CHO2 Phosphatidyl-ethanolamine N-methyltransferase YGR158C 0.310167656 0.154868067 0.019048651 0.865638825 MTR3 nucleolar protein involved in mRNA transport YGR159C 1.433290815 0.19832217 -0.402660389 0.002428318 NSR1 nuclear localization sequence binding protein YGR160W 0.254563456 0.634046817 -0.738982831 0.011135784 questionable ORF YGR161C 0.146395644 0.6986124 0.081928186 0.57267813 hypothetical protein YGR162W 0.301467441 0.565044564 -0.25876581 0.108460121 TIF4631 mRNA cap-binding protein (eIF-4F), 150K subunit , highly homologous to Tif4632p, homologs of mammalian p220 YGR163W -0.46522764 0.055714147 -0.028989435 0.326712515 GTR2 (putative) small GTPase, similar to Gtr1 YGR164W 0.077093662 0.792711917 0.330031129 0.405727483 questionable ORF YGR165W 0.437317265 0.150957794 0.106911395 0.279241218 hypothetical protein YGR166W 1.957216013 0.123050509 0.226059446 0.079034555 KRE11 involved in cell wall biogenesis YGR167W 0.21164061 0.256580966 -0.135569763 0.456059764 CLC1 Clathrin light chain YGR168C 0.135048146 0.354120838 -0.167150551 0.52903482 hypothetical protein YGR169C 0.163639678 0.432149113 -0.21288136 0.167242827 similarity to Rib2p YGR171C 0.259690364 0.150421544 0.01571259 0.739676026 MSM1 mitochondrial methionyl-tRNA synthetase YGR172C 0.40846631 0.15379209 0.689115771 0.040044404 YIP1 Golgi integral membrane protein, interacts with Ypt proteins YGR173W 0.565973056 0.132941039 -0.353907119 0.079308255 strong similarity to human GTP-binding protein YGR174C -0.3175136 0.462679618 0.03480879 0.830498154 CBP4 ubiquinol--cytochrome-c reductase assembly factor YGR175C 0.381667679 0.592202565 0.123166763 0.361437719 ERG1 Squalene monooxygenase YGR176W 0.260040914 0.571964486 0.621535149 0.037207465 questionable ORF YGR177C 0.576996178 0.326334537 0.092706233 0.486021999 ATF2 Alcohol acetyltransferase YGR178C -0.04088992 0.88795945 0.026863749 0.83411597 PBP1 interacts with poly(A)-binding protein YGR179C -0.26501513 0.041750981 -0.497706971 0.078405462 hypothetical protein YGR180C 0.659924072 0.462748805 0.526466539 0.153283852 RNR4 Ribonucleotide Reductase YGR181W 0.019900214 0.931828345 0.277337537 0.001306275 TIM13 Subunit of mitochondrial protein import machinery YGR182C -0.97923913 0.002251397 0.057651361 0.705931701 questionable ORF YGR183C -0.94853975 0.005690217 -0.049502896 0.402609417 QCR9 7.3 kDa subunit 9 of the ubiquinol cytochrome c oxidoreductase complex YGR185C 1.108702654 0.25843125 0.022794105 0.723773434 TYS1 tyrosyl-tRNA synthetase, cytoplasmic YGR186W -0.31071757 0.209377792 -0.502077355 0.053628213 TFG1 Transcription factor TFIIF large subunit YGR187C 0.93683661 0.200667375 -0.69328914 0.09582857 HGH1 (putative) Hmg1 /2 protein YGR188C -0.02019959 0.948657422 -0.309275286 0.212511438 BUB1 Serine /threonine protein kinase required for cell cycle arrest in response to loss of microtubule function YGR189C 2.249648859 0.22341789 0.445000867 0.143350482 CRH1 Cell wall protein YGR190C 0.627075464 0.005917838 0.282406874 0.19419146 questionable ORF YGR191W 0.584922249 0.002341945 0.523726363 0.095125367 HIP1 histidine permease YGR192C 0.880923937 0.191531829 0.768922948 0.159502261 TDH3 Glyceraldehyde-3-phosphate dehydrogenase 3 YGR193C 0.322506154 0.001541844 -0.082844217 0.368053388 PDX1 Protein X component of mitochondrial pyruvate dehydrogenase complex YGR194C -1.0984037 0.012850279 0.046121844 0.693754546 XKS1 Xylulokinase YGR195W 0.936708053 0.05844103 -0.052207337 0.544197335 SKI6 homolog of RNAse PH YGR196C 0.162410826 0.486737073 -0.668666436 0.008661067 weak similarity to Tetrahymena acidic repetitive protein arp1 YGR197C 0.072043158 0.762477051 0.276670039 0.14385776 SNG1 involved in nitrosoguanidine resistance YGR198W 0.958001362 0.173239509 -0.385717828 0.056613995 hypothetical protein YGR199W -0.41732521 0.041995775 0.236771216 0.208672399 PMT6 dolichyl phosphate-D-mannose:protein O-D-mannosyltransferase YGR200C 0.22269841 0.389854489 -0.10866288 0.29611013 ELP2 90 kD subunit of elongator and elongating RNA pol II holoenzyme YGR201C -1.74512325 0.003615327 0.236366844 0.388325985 strong similarity to translation elongation factor eEF1 alpha chain Cam1p YGR202C 0.103469524 0.509364408 -0.781523078 0.008668422 PCT1 phosphorylcholine transferase ; or cholinephosphate cytidylyltransferase YGR203W 0.973449016 0.090867581 0.606918829 0.124444772 weak similarity to X.laevis protein-tyrosin-phosphatase cdc homolog 2 and to hypothetical protein YPR200c YGR204W 0.196387476 0.139415125 0.629932888 0.142758822 ADE3 encodes the cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase YGR205W -0.73083948 0.024880422 0.232050495 0.33139012 similarity to S.pombe hypothetical protein D89234 YGR206W -0.80487028 0.003776645 0.102067358 0.445067705 similarity to Xenopus transcription factor Oct-1.17 YGR207C 0.031954838 0.906355555 -0.562327279 0.073153342 ETF-BETA electron-transferring flavoprotein, beta chain YGR208W 1.368772651 0.042959768 -0.017833859 0.907245817 SER2 phosphoserine phosphatase YGR209C 0.43753087 0.022837415 0.587052357 0.033462491 TRX2 thioredoxin YGR210C -0.5759268 0.030195896 0.044790756 0.571796704 similarity to M.jannaschii GTP-binding protein and to M.capricolum hypothetical protein SGC3 YGR211W 0.23539715 0.365436635 0.346291225 0.020361386 ZPR1 zinc finger protein YGR212W 0.2055298 0.061377787 0.066407592 0.194434172 weak similarity to S.pombe hypothetical protein SPAC18B11.03c YGR213C 0.471887069 0.504887559 0.218751236 0.2413573 RTA1 involved in 7-aminocholesterol resistance YGR214W 0.905528953 0.004652697 0.316660171 0.010957085 RPS0A Ribosomal protein S0A YGR215W 0.502387534 0.010096626 0.025541179 0.870654737 RSM27 protein of the small subunit of the mitochondrial ribosome YGR216C 0.675450696 0.004291721 0.382225143 0.18503978 GPI1 involved in first step of GPI (N-acetylglucosaminylphosphatidylinositol) anchor synthesis YGR218W -0.57274737 0.096047594 0.201044941 0.044773308 CRM1 omosome region maintenance protein YGR219W 0.723359781 0.02823017 -0.146592818 0.384818643 questionable ORF YGR220C 0.214321804 0.265957365 -0.219436496 0.136857375 MRPL9 Mitochondrial ribosomal protein MRPL9 (YmL9) (E. coli L3) (human MRL3) YGR221C -1.35671699 0.009341723 0.310381265 0.124863976 TOS2 similarity to hypothetical protein YHR149c YGR222W -0.0897455 0.594517722 -0.167207322 0.284989192 PET54 translational activator of cytochrome c oxidase subunit III YGR223C 0.129292118 0.604239251 -0.048064197 0.1121444 weak similarity to hypothetical protein YFR021w YGR224W 1.144797322 0.007231496 0.478649897 0.042496623 AZR1 small molecule transport/MFS-MDR YGR225W -1.10864586 0.035220555 0.249186062 0.469505786 AMA1 Required for sporulation ; highly induced during sporulation YGR226C 0.322983473 0.251645697 0.209694744 0.286089768 hypothetical protein YGR228W 0.159867805 0.42088248 -1.267416922 0.012059019 questionable ORF YGR229C 1.006304631 0.258143628 -0.507559358 0.149194917 SMI1 57 kDa nuclear protein YGR230W 0.539263724 0.220426426 -0.256859132 0.326511052 BNS1 similar to Spo12, involved in sporulation YGR231C 0.062864077 0.680118357 -0.41330347 0.023458103 PHB2 mitochondrial protein, prohibitin homolog ; homolog of mammalian BAP37 and S. cerevisiae Phb1p YGR232W 0.001568921 0.991403369 0.165958238 0.114856544 NAS6 Interaction with the 19S regulatory particle of the 26S proteasome detected by coimmunoprecipitation YGR233C -1.53251546 0.004199795 -0.073728448 0.428484293 PHO81 Pho85 kinase inhibitor YGR234W 0.373610852 0.320131068 0.443626734 0.002873872 YHB1 Flavohemoglobin YGR235C -0.04660157 0.808153924 -0.132168199 0.087732018 hypothetical protein YGR236C -1.67234003 0.030497721 0.060493875 0.768258884 SPG1 stationary phase gene YGR237C -0.35816185 0.01026221 -0.320378411 0.01599475 weak similarity to YOR019w YGR238C -0.80632228 0.042893614 -0.236480267 0.343200747 KEL2 involved in cell fusion and morphology ; contains six Kelch repeats YGR239C 0.792685529 0.284689434 0.039320545 0.574581683 PEX21 Peroxin Pex21p YGR240C 0.345541092 0.37851418 0.212295088 0.069178448 PFK1 phosphofructokinase alpha subunit YGR241C 0.009674497 0.976686178 0.337848537 0.038883796 YAP1802 member of clathrin assembly polypeptide AP180 family YGR242W 0.366255602 0.717458956 0.031389723 0.886155725 questionable ORF YGR243W -1.33425269 0.013788224 0.258429873 0.237325777 strong similarity to hypothetical protein YGR243w//strong similarity to hypothetical protein YHR162w YGR244C -0.76830403 0.059589909 0.259687498 0.132493826 LSC2 Succinate-CoA Ligase (ADP-Forming) YGR245C 0.740041817 0.008890811 -0.372376229 0.025733918 SDA1 Severe Depolymerization of Actin YGR246C -0.51838385 0.090954986 0.021874651 0.901597328 BRF1 RNA polymerase III transcription factor with homology to TFIIB YGR247W -0.98388934 0.035337703 -0.067966372 0.274072726 hypothetical protein YGR248W -3.05069509 6.70854E-05 0.104138306 0.611072488 SOL4 similar to SOL3 YGR249W -2.02105903 0.006992032 0.304105286 0.226486698 MGA1 Mga1p shows similarity to heat shock transcription factor YGR250C -0.87347146 0.010399815 -0.588631376 0.002995777 weak similarity to human cleavage stimulation factor 64K chain YGR251W 0.528064286 0.237913357 -0.567860674 0.088737055 hypothetical protein YGR252W 0.249642663 0.174758461 -0.164087624 0.017600794 GCN5 histone acetyltransferase YGR253C 0.068309879 0.890347101 -0.53233139 0.071694996 PUP2 Proteasome subunit YGR254W -0.21950997 0.573279469 0.173513849 0.412884213 ENO1 enolase I YGR255C 0.62745397 0.307772755 0.233738138 0.273800646 COQ6 COQ6 monooxygenase YGR256W -2.59716225 0.001641311 -0.104964865 0.753278712 GND2 6-phosphogluconate dehydrogenase YGR257C 0.582186635 0.074956432 -0.369807549 0.004684275 similarity to C.elegans C16C10.1 homolog of xeroderma pigmentosum group G (XPG) protein, copufurifies with transcription factor, TFIIH, mRNA is cell cycle regulated and YGR258C -0.61530941 0.053489324 -0.317812262 0.12786496 RAD2 induced by DNA damage and by meiosis (different cis-sites utilized in damage and meiotic induction YGR259C 0.227978928 0.56995863 0.226132746 0.532845658 questionable ORF YGR260W 0.361676936 0.411983663 0.417039553 0.320754886 TNA1 Tna1p is a high affinity nicotinic acid plasma membrane permease YGR261C 0.153924585 0.425155493 -0.109426796 0.478531639 APL6 putative beta adaptin component of the membrane-associate clathrin assembly complex YGR262C -0.36091999 0.076723959 0.06545637 0.582528345 ser/thr protein kinase YGR263C -0.09540075 0.623510438 0.477773475 0.011057239 weak similarity to E.coli lipase like enzyme YGR264C 1.289294917 0.143007878 -0.114142019 0.155246184 MES1 methionyl tRNA synthetase YGR265W 1.070077689 0.02773434 0.190029345 0.054850704 questionable ORF YGR266W 0.008438963 0.973587904 -0.027581454 0.531673907 hypothetical protein YGR267C 0.099319025 0.533873661 -0.132155977 0.199577706 FOL2 GTP-cyclohydrolase I YGR268C -0.0939989 0.820277661 0.554190402 0.070399823 weak similarity to S.pombe hypothetical protein SPAC17A5 YGR269W 1.176581976 0.407347222 0.185856418 0.554719738 questionable ORF YGR270W -0.4494557 0.137235601 -0.193942507 0.1502483 YTA7 26S proteasome ATPase YGR271W -0.16009157 0.468924299 0.042734814 0.86068605 strong similarity to S.pombe RNA helicase YGR272C 1.140846422 0.116135538 -1.208853937 0.021456802 similarity to hypothetical S.pombe protein SPAC12G12.02 YGR273C 0.31752713 0.587981105 0.505347531 0.390372455 similarity to hypothetical protein YMR295c YGR274C 0.19708739 0.453305159 -0.27476247 0.093894561 TAF145 TFIID 145 KDa subunit YGR275W 0.032496077 0.898989127 -0.218570857 0.192122298 RTT102 regulator of Ty1 transposition YGR276C -0.17074037 0.343708113 -0.649249304 0.020359505 RNH70 ribonuclease H YGR277C 0.000688722 0.997331789 -0.327442612 0.064469853 similarity to hypothetical S.pombe protein YGR278W 0.27070663 0.241587897 -0.268881087 0.066745168 similarity to C.elegans LET-858 YGR279C 0.528805239 0.362499081 0.81522253 0.059839819 SCW4 soluble cell wall protein ; can be released from SDS-extracted cell walls under reducing conditions YGR280C 0.565105343 0.235585045 -0.804323575 0.027013763 weak similarity to Cbf5p YGR281W -0.89563402 0.034346317 0.210350566 0.264655391 YOR1 ABC transporter YGR282C 1.397834203 0.230180937 0.602444244 0.217841958 BGL2 Cell wall endo-beta-1,3-glucanase YGR283C 1.333078004 0.060995305 0.109389504 0.447374217 similarity to hypothetical protein YMR310c YGR284C -0.11521695 0.697206685 0.045838064 0.769995263 ERV29 ER-Golgi transport vesicle protein YGR285C 0.694542529 0.055285903 0.571070861 0.001189185 ZUO1 Zuotin, putative Z-DNA binding protein YGR286C -0.72026533 0.039008709 0.007608952 0.970664509 BIO2 Biotin synthase YGR287C -1.34340446 0.01764757 -0.057013756 0.72362413 strong similarity to maltase YGR288W 0.104566979 0.863649221 0.024344927 0.879209614 MAL13 MAL-activator protein YGR289C -1.2517479 0.002823882 0.378641918 0.345670103 MAL11 Alpha-glucoside transporter ; maltose permease YGR290W 0.120926803 0.864783541 -0.542162599 0.292845351 hypothetical protein YGR291C -0.7013692 0.038622533 0.380458579 0.510008252 hypothetical protein YGR292W -1.11477474 0.007788982 -0.067178641 0.68848526 MAL12 alpha-glucosidase of the MAL1 locus YGR293C 0.215429419 0.073104369 0.228718214 0.352444136 strong similarity to hypothetical protein YBR300c YGR294W 0.154276356 0.362531736 0.414835223 0.129257955 strong similarity to members of the Srp1p/Tip1p family YGR295C -0.45967222 0.246984692 0.13057919 0.440358725 COS6 similar to other subtelomerically-encoded proteins YHL001W 1.703989493 0.014953649 0.219833568 0.025672879 RPL14B Ribosomal protein L14B YHL002W 0.169409203 0.227953354 0.046157254 0.40074328 SH3 domain YHL003C -0.27473027 0.190104808 -0.152452128 0.377444723 LAG1 longevity-assurance protein YHL004W 0.741307402 0.126367812 0.256858794 0.145458246 MRP4 mitochondrial ribosomal protein, homologous to E. coli ribosomal protein S2, component of the 37 S subunit of mitochondrial ribosomes YHL005C 0.197844031 0.640882149 0.287854544 0.018694264 hypothetical protein YHL006C 0.5006168 0.16272783 0.440998503 0.087130276 SHU1 suppressor of HU sensitivity of sgs1 mutations YHL007C 0.092071198 0.706929839 0.148233243 0.139363867 STE20 serine /threonine protein kinase YHL008C -0.69115676 0.142903534 0.191855095 0.495945352 Potential formate transporter nirC YHL009C -0.63446494 0.026619037 -0.476225797 0.054013178 YAP3 bZip DNA binding proteins YHL009W-A -0.75550557 0.037930741 -0.518234108 0.138522511 TyA gag protein. Gag processing produces capsid proteins. YHL011C 0.633922201 0.242202075 -0.104516803 0.132047194 PRS3 ribose-phosphate pyrophosphokinase 3 YHL012W 0.923944545 0.106723654 0.140768849 0.179438337 UDP Glucose pyrophosphorylase YHL013C 0.424282916 0.032448931 -0.789416361 0.045730037 similarity to C.elegans hypothetical protein F21D5.2 YHL014C -0.1346036 0.537585433 -0.595671268 0.032309764 YLF2 GTP-binding protein and glycogen phosphorylase (weak) YHL015W 0.874570837 0.062183127 -0.346054478 0.095767284 RPS20 Ribosomal protein S20 YHL016C -1.25509128 0.085062945 0.25223857 0.427019334 DUR3 Urea transporter YHL017W -0.22041028 0.471786785 -0.050600381 0.858752257 Probable transmembrane protein PTM1 YHL018W 0.353762018 0.381349214 0.176811489 0.164986455 Dimerization cofactor of homeodomian protein NF1-alpha YHL019C -0.51618054 0.073210578 -0.328440609 0.075194349 APM2 Similiar to clathrin coat proteins YHL020C 0.297069908 0.639095974 -0.103316301 0.408974033 OPI1 negative regulator of phospholipid biosynthesis YHL021C 0.506153964 0.598249896 0.38725502 0.265355104 weak similarity to Pseudomonas gamma-butyrobetaine hydroxylase YHL022C 0.375683618 0.504008039 0.222296026 0.059594746 SPO11 Encodes one of the earliest meiosis-specific recombination functions. YHL023C -0.63936933 0.046717914 -0.069831876 0.48875303 hypothetical protein YHL024W -0.40524323 0.425195742 0.262778756 0.252976979 RIM4 RNA-binding protein of the RRM class (putative) YHL025W -0.21283942 0.297324418 -0.298369117 0.26418369 SNF6 subunit of the chromatin remodeling Snf /Swi complex YHL026C 0.368162449 0.575263228 0.302359944 0.016110602 hypothetical protein YHL028W -1.54029824 0.00335701 0.245428226 0.372887528 WSC4 Putative integral membrane protein containing novel cysteine motif. Similarity to SLG1 (WSC1), WSC2 and WSC3 YHL029C 0.766228834 0.003879005 0.305558493 0.064787062 hypothetical protein YHL030W -0.18091916 0.439355999 0.045551418 0.109930881 ECM29 involved in cell wall biogenesis YHL031C -0.21642045 0.306037277 0.492972193 0.047264901 GOS1 Golgi SNARE protein YHL032C -1.1518371 0.063867672 0.396930537 0.069655484 GUT1 glyerol kinase (converts glycerol to glycerol-3-phosphate YHL033C 1.16890719 0.014402862 0.301355911 0.00110139 RPL8A Ribosomal protein L8A (rp6) (YL5) (L4A) YHL034C -0.05130939 0.77720484 0.094471586 0.112651875 SBP1 Single-strand nucleic acid binding protein YHL035C -0.29258963 0.374674738 -0.013313141 0.935382792 ABC transporter YHL036W -0.16415202 0.396728793 0.248338992 0.010743036 MUP3 very low affinity methionine permease YHL037C 1.174908398 0.445698719 0.013795049 0.892388883 hypothetical protein YHL038C -0.13423601 0.471510757 -0.14161606 0.131891928 CBP2 Cytochrome B pre-mRNA processing protein YHL039W 0.474909855 0.022989247 0.131567476 0.146149547 weak similarity to YPL208w YHL040C 0.501910608 0.257440455 0.464145522 0.087185742 ARN1 ferrichrome-type siderophore transporter YHL041W -0.67746604 0.042474659 -0.397936512 0.384875814 weak similarity to Drosophila hypothetical protein 6 YHL042W -0.03222344 0.653448424 0.16809894 0.276864062 similarity to subtelomeric encoded proteins YHL043W -0.4747536 0.010660598 0.072100393 0.744990659 ECM34 ExtraCellular Mutant//involved in cell wall biogenesis and architectureinvolved in cell wall biogenesis and architecture YHL044W -0.57225626 0.001966708 -0.228104541 0.062081365 similarity to subtelomeric encoded proteins YHL045W -0.21662926 0.588610206 0.367547148 0.501879328 strong similarity to subtelomeric encoded proteins YHL046C 0.255686069 0.521141583 0.698883144 0.064260303 strong similarity to members of the Srp1p/Tip1p family YHL047C 0.124629528 0.804537092 -0.111151702 0.238641369 TAF1 Triacetylfusarinine C transporter YHL048W -0.30467617 0.484831893 -0.213599232 0.172943342 COS8 similar to other subtelomerically-encoded proteins YHL049C -0.73261789 0.010757523 0.453262815 0.146694368 strong similarity to subtelomeric encoded proteins YHL050C -1.22554239 0.00322466 0.387532647 0.231977115 strong similarity to subtelomeric encoded proteins YHR001W -1.28884548 0.002742997 -0.360850981 0.022823205 60kD chaperonin (weak) YHR002W -0.60461553 0.038229672 -0.354029054 0.070286437 Mitochondrial carrier protein /Grave's disease carrier protein YHR003C 0.278038647 0.032246641 -0.466508303 0.031682942 thiF, moeB, ubiquitin activating enzyme (all weak) YHR004C -0.6004327 0.045350886 -0.102434147 0.363599026 NEM1 Nuclear Envelope Morphology YHR005C 0.123188552 0.298705672 -0.42238405 0.079720114 GPA1 alpha subunit of G protein coupled to mating factor receptors YHR005C-A 1.093135976 0.013751446 0.177392491 0.48113003 MRS11 component of mitochondrial import machinery YHR006W 0.266687658 0.490222003 0.33826826 0.016509902 STP2 Zinc finger (Cys(2)-His(2)) YHR007C 0.105946748 0.795140659 0.279781508 0.237388994 ERG11 cytochrome P450 lanosterol 14a-demethylase YHR008C -1.91592298 0.000839021 0.507213172 0.072083811 SOD2 Manganese-containing superoxide dismutase YHR009C 0.194491912 0.534673426 0.544938606 0.095125598 similarity to S.pombe hypothetical protein YHR010W 1.528535589 0.093482478 -0.034577612 0.875676605 RPL27A Ribosomal protein L27A YHR011W -0.41563418 0.131682792 -0.372849548 0.096312595 DIA4 Seryl-tRNA synthetase YHR012W -0.34790686 0.04794147 -0.334534634 0.098779559 VPS29 involved in vacuolar protein sorting YHR013C 0.290773926 0.309877011 0.061843534 0.516317857 ARD1 subunit of the major N alpha-acetyltransferase ; complexes with Nat1p YHR014W 0.315743047 0.270687936 0.127871239 0.644644463 SPO13 sporulation protein YHR015W -1.86580598 0.008292054 -0.675955259 0.098251172 MIP6 PolyA-binding protein YHR016C -0.99287008 0.016201804 -0.031180463 0.583886788 YSC84 SH3 domain in C-terminus YHR017W -0.08106326 0.711889689 0.028357169 0.740832184 YSC83 similar to S. douglasii YSD83 YHR018C 1.208241348 0.350886743 -0.13634341 0.353000658 ARG4 argininosuccinate lyase YHR019C 0.265809374 0.072068645 0.30016003 0.046733317 DED81 Asparaginyl-tRNA synthetase YHR020W 0.434144015 0.013290724 -0.220135182 0.103877662 Aminoacyl tRNA-synthetase YHR021C 2.175756787 0.027671927 0.690090147 0.023466091 RPS27B 40S Ribosomal protein S27B (rp61) (YS20) YHR021W-A 0.261374039 0.537325613 0.233401905 0.407365047 ECM12 (putative) involved in cell wall biogenesis YHR022C 0.670719224 0.242592767 0.200603925 0.03778279 RAS-related protein YHR023W 0.503771159 0.590566551 -0.069285625 0.532404662 MYO1 Class II Myosin YHR024C 1.003996046 0.053263979 -0.017681058 0.62682353 MAS2 53 kDa subunit of the mitochondrial processing protease YHR025W 1.007435303 0.109757319 0.417886016 0.129155104 THR1 homoserine kinase YHR026W 0.557309724 0.232133195 0.269186173 0.030278427 PPA1 vacuolar ATPase V0 domain subunit c'' YHR027C 0.029245109 0.871054466 -0.238628503 0.071941966 RPN1 Subunit of 26S Proteasome (PA700 subunit) YHR028C -0.6399085 0.050951438 0.142477545 0.226041755 DAP2 Dipeptidyl aminopeptidase B (DPAP B) YHR029C -0.89117047 0.0355358 -0.518984869 0.034609776 Thymidylate synthase (putative ; weak) YHR030C 0.853698078 0.286745249 -0.09817604 0.419527221 SLT2 serine /threonine MAP kinase YHR031C -0.1144014 0.722751871 -0.180359154 0.083848929 RRM3 DNA helicase YHR032W 0.08136409 0.835950796 0.164696431 0.416744217 ethionine resistance protein YHR033W -0.80367965 0.232810578 0.877507754 0.114641658 Pro1p (Gamma-glutamyl kinase) YHR034C -0.67233881 0.097187307 0.110794198 0.437200072 hypothetical protein YHR035W 0.594814755 0.199394067 0.138502455 0.133744291 weak similarity to human Sec23 protein YHR036W 0.326704272 0.13417374 0.025295974 0.807163963 similarity to hypothetical protein YGL247w YHR037W -0.34198777 0.160697331 -0.098943493 0.143253896 PUT2 delta-1-pyrroline-5-carboxylate dehydrogenase YHR038W 0.657014023 0.024244405 -0.346575989 0.236461162 FIL1 Putative mitochondrial ribosome recycling factor YHR039C -0.28177403 0.013396827 0.308465233 0.007693046 Aldehyde dehydrogenases YHR040W -0.56838253 0.13224627 -0.247787242 0.050281913 weak similarity to Hit1p YHR041C 0.669049495 0.121764764 0.861711004 0.06723048 SRB2 RNA polymerase II holoenzyme /mediator subunit YHR042W 0.309984566 0.363063539 0.755379039 0.047452351 NCP1 NADP-cytochrome P450 reductase YHR043C -0.17127183 0.702095199 -0.16862018 0.08037727 DOG2 2-deoxyglucose-6-phosphate phosphatase YHR044C -0.06366259 0.866612295 -0.21479172 0.027141704 DOG1 2-deoxyglucose-6-phosphate phosphatase YHR045W 0.474988847 0.02191573 0.036194147 0.644135208 hypothetical protein YHR046C 0.466489252 0.250596663 -0.326654357 0.033645146 Inositol monophosphatase YHR047C 0.524318583 0.177190497 0.380622937 0.021010788 AAP1' arginine /alanine aminopeptidase YHR048W 0.927406157 0.113460005 0.288187282 0.075437781 similarity to multidrug resistance proteins YHR049C-A 1.082593719 0.098785229 0.437825833 0.017522041 questionable ORF YHR049W 1.763368304 0.17020191 0.136029047 0.337502972 similarity to S.pombe dihydrofolate reductase and YOR280c YHR050W 0.16632212 0.565428224 0.534845584 0.115838845 SMF2 localized to mitochondrial membrane YHR051W -1.59075669 0.000966808 -0.415742798 0.006225004 COX6 subunit VI of cytochrome c oxidase YHR052W 1.287386697 0.077484986 -0.594289633 0.115632555 weak similarity to P.yoelii rhoptry protein YHR053C -0.9056248 0.000213858 -0.161247146 0.195232285 CUP1-1 copper-binding metallothionein YHR054C -1.73559725 0.000881801 -0.083869977 0.188773404 weak similarity to YOR262w YHR055C -0.793701 0.001171231 -0.275752243 0.213574342 CUP1-2 copper-binding metallothionein YHR056C -1.05166452 0.001265546 0.240924711 0.170556502 ORF-X' in the CUP1 repeat region YHR057C -0.90036025 0.00218626 0.340155959 0.040117038 CYP2 Peptidylprolyl isomerase (cyclophilin) ER or secreted YHR058C -0.18629987 0.290102504 -0.214539597 0.048613191 MED6 RNA polymerase II mediator subunit YHR059W 0.898887805 0.084846903 -0.005435989 0.958244854 weak similarity to Ustilago hordei B east mating protein 2 YHR060W -0.17767955 0.637255223 -0.799937176 0.068220265 VMA22 vacuolar H+-ATPase assembly protein YHR061C 0.540709783 0.052633572 0.276148253 0.038369782 GIC1 interacts with GTPase, involved in bud emergence YHR062C 0.952800577 0.02590862 0.049684216 0.77960657 RPP1 Protein subunit of nuclear ribonuclease P (RNase P) YHR063C 0.881859791 0.396487063 -0.14169076 0.316345916 PAN5 Ketopantoate Reductase YHR064C 1.11513957 0.274795944 0.046993172 0.494261472 PDR13 Hsp70 Protein RRP3 is a DEAD box gene homologous to eIF-4a which encodes an RNA-dependent ATPase possessing helicase activity which is not specific YHR065C 0.520439699 0.180794079 -0.621759101 0.057584468 RRP3 for RNA YHR066W 1.086103811 0.058825821 -0.576103287 0.160133322 SSF1 homologous to Ssf2p YHR067W -0.15578463 0.700109194 0.030627129 0.806082766 hypothetical protein YHR068W 1.425360821 0.193100944 0.298298149 0.166841745 DYS1 Deoxyhypusine synthase YHR069C 0.762321025 0.14209158 -0.254412372 0.050335213 RRP4 3->5 exoribonuclease ; Component of the exosome 3->5 exonuclease complex with Rrp41p, Rrp42p, Rrp43p and Dis3p (Rrp44p). YHR070W 0.511395346 0.02987825 0.235140752 0.078590545 strong similarity to N.crassa met-10+ protein YHR071W 0.520121392 0.289934117 0.02091108 0.823211638 PCL5 G1 /S cyclin (weak) YHR072W 0.02474641 0.890464456 0.089162636 0.043174191 ERG7 2,3-oxidosqualene-lanosterol cyclase YHR072W-A 1.578518266 0.021117818 0.191510858 0.410517505 NOP10 Component of H /ACA-box snoRNPs YHR073W 0.23466517 0.182955189 -0.059121193 0.115755461 OSH3 Oxysterol-binding protein YHR074W -0.67439849 0.06413981 0.089955636 0.534714555 QNS1 weak similarity to B.subtilis spore outgrowth factor B YHR075C -1.39841012 0.000336301 -0.289721299 0.077420809 PPE1 ribosomal protein of the small subunit, mitochondrial /carboxyl methyl esterase YHR076W -0.9911158 0.014018701 -0.259846635 0.033257415 weak similarity to C.elegans hypothetical protein CEW09D10 YHR077C 0.094437324 0.211864325 -0.248273562 0.204285488 NMD2 Highly acidic C-terminus YHR079C -0.0797747 0.40562298 0.921384414 0.015356841 IRE1 Ire1p is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities YHR080C -0.78595783 0.027401721 0.713282885 0.245050664 similarity to hypothetical protein YDR326c, YFL042c and YLR072w YHR081W 0.59521292 0.061544161 -0.111711418 0.320345297 weak similarity to human C1D protein YHR083W -0.54599489 0.087391487 -0.682792968 0.084318999 hypothetical protein YHR084W 0.430234845 0.058687492 0.356296861 0.084808579 STE12 Transcription factor YHR085W 1.376273892 0.067821032 0.6932294 0.047723499 weak similarity to fruit fly brahma transcriptional activator YHR086W -0.39551625 0.067685125 -0.206416466 0.423152802 NAM8 putative RNA binding protein, involved in meiosis-specific splicing of the REC107 transcripts in cooperation with the Mer1 protein YHR087W -1.42775287 0.014126441 0.201581048 0.179335187 hypothetical protein YHR088W 0.75127057 0.037388357 0.17350043 0.301787357 RPF1 similarity to hypothetical protein YNL075w YHR089C 1.491385459 0.158550081 -0.496060108 0.184374179 GAR1 small nucleolar RNP proteins YHR090C -0.2875236 0.326839861 0.143541684 0.102858712 YNG2 NuA4 histone acetyltransferase complex component YHR091C 0.022984675 0.898892028 -0.569832518 0.102572644 MSR1 Arginyl-tRNA synthetase YHR092C -0.70701111 0.351587942 0.171362223 0.066003985 HXT4 High-affinity glucose transporter the AHT1 DNA sequence is upstream of HXT4 and contains an HXT4 regulatory element which is a multicopy suppressor of glucose transport YHR093W 0.411938884 0.491298246 0.573519666 0.078974959 AHT1 defects ; probable non-functional ORF YHR094C 0.730722646 0.35708953 0.377391135 0.422649731 HXT1 High-affinity hexose (glucose) transporter YHR095W 0.626624451 0.139053731 0.513771653 0.105125437 hypothetical protein YHR096C -1.7941009 0.005037945 1.334048652 0.268296644 HXT5 hexose transporter YHR098C 0.252355495 0.513268143 0.548181753 0.099785833 SFB3 binds to Sed5p and Sec23p by distinct domains YHR100C -0.33376095 0.371661916 0.700705475 0.083092909 hypothetical protein YHR101C -0.21305077 0.213689181 0.231859985 0.057302068 BIG1 involved in cell growth and size YHR103W 0.13538419 0.434733567 -0.374660027 0.098945709 SBE22 involved in bud growth YHR104W -1.08570408 0.019635441 0.133912931 0.641899153 GRE3 a keto-aldose reductase YHR105W -0.58925258 0.008748452 -0.119382618 0.111879633 weak similarity to Mvp1p YHR106W -1.24069228 0.000135022 0.106623455 0.355042309 TRR2 mitochondrial thioredoxin reductase YHR107C 0.416065801 0.313566188 -0.050605888 0.770686761 CDC12 Component of 10 nm filaments of mother-bud neck (septin) YHR108W 0.185939518 0.285338509 0.445778602 0.013972345 GGA2 Arf-binding protein YHR109W -0.30453018 0.271248799 -0.145992781 0.294923163 CTM1 Cytochrome c methyltransferase YHR110W -0.15798353 0.285774294 -0.091529155 0.088167437 ERP5 p24 protein involved in membrane trafficking YHR111W -0.07172194 0.721769538 -0.102674617 0.25760136 moeB, thiF, UBA1 YHR112C -0.80968321 0.023013865 -0.166711759 0.137976526 Cystathionine gamma-synthase YHR113W -0.81974015 0.024144998 0.180807828 0.268320657 Vacuolar aminopeptidase YHR114W -0.3293218 0.017996836 -0.183604629 0.224227021 BZZ1 Myo3 /5p-Bee1p-Vrp1p actin assembly complex component YHR115C -0.20001606 0.27700481 0.307478871 0.09555716 strong similarity to hypothetical protein YNL116w YHR116W 0.828605039 0.125133911 0.320404565 0.145923483 hypothetical protein YHR117W -0.59141567 0.011672334 -0.019256597 0.855403279 TOM71 71-kDa component of the protein translocase of the outer membrane of mitochondria YHR118C 0.398191835 0.039512797 -0.280727138 0.002493837 ORC6 50-kDa subunit of ORC YHR119W 0.037019078 0.899974058 0.310880472 0.082583845 SET1 involved in chromatin-mediated gene regulation / trithorax YHR120W 0.731396567 0.22593704 -0.410869526 0.057922656 MSH1 mutS homolog involved in mitochondrial DNA repair YHR121W 0.23546585 0.170920074 -0.293614839 0.087363005 weak similarity to C.elegans hypothetical protein YHR122W 0.290516884 0.511367378 -0.454088397 0.014931859 similarity to hypothetical C. elegans protein F45G2.a YHR123W 1.469421843 0.152960586 0.43464764 0.122023103 EPT1 sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase YHR124W -0.10168322 0.680336847 0.048664854 0.744193693 NDT80 DNA-binding transcription factor that activates middle sporulation genes YHR125W 0.283948896 0.400620666 0.159095976 0.517667064 questionable ORF YHR126C -0.17854284 0.756274863 0.769362309 0.030295907 hypothetical protein (H)igh copy (S)uppressor of (N)34 dominant negative allele of SEC4. Suppression is very specific to this allele. It has no affect on the YHR127W 0.077049149 0.8448317 0.158306861 0.237550777 HSN1 analogous YPT1 allele. No homology or known function. YHR128W 0.7904179 0.311448917 -0.004708133 0.966127234 FUR1 UPRTase YHR129C -0.36244395 0.48009763 -0.035667713 0.891465152 ARP1 Centractin YHR130C 0.141675511 0.282507793 0.333469076 0.211537839 YHR131C -0.11852997 0.271168751 0.139696261 0.217567818 Highly acidic C-terminus YHR132C 0.095084156 0.818468667 0.454236812 0.219786603 ECM14 Carboxypeptidase YHR133C 0.975753542 0.13731858 -0.063938044 0.144825257 hypothetical protein YHR134W 0.615336015 0.003742255 -0.052330627 0.375344178 WSS1 Weak suppressor of smt3 mutant YHR135C -0.21423215 0.621814499 0.206329219 0.266871033 YCK1 membrane-bound casein kinase I homolog YHR136C -1.43999234 0.048978586 0.560841527 0.147735751 SPL2 17 kDa protein YHR137W -1.32751075 0.000504292 0.757847274 0.047656431 ARO9 aromatic amino acid aminotransferase II YHR138C -0.91748654 0.096292939 -0.145953593 0.578322018 hypothetical protein YHR139C -3.7282522 0.0002836 0.158940966 0.433418657 SPS100 sporulation-specific wall maturation protein YHR139C-A -0.72406884 0.33188876 0.293328054 0.551516688 hypothetical protein YHR140W -2.61008669 0.000188247 0.426368166 0.466843453 hypothetical protein YHR141C 1.518585016 0.071401945 0.362117748 0.070641919 RPL42B Ribosomal protein L42B (YL27) (L41B) (YP44) YHR142W 1.451853247 0.039783606 0.438635185 0.061248974 CHS7 The seventh gene identified that is involved in chitin synthesis ; involved in Chs3p export from the ER YHR143W 1.273840915 0.344033007 1.053395568 0.043898363 Ser-Thr rich protein YHR143W-A 2.027108834 0.045258535 0.034372907 0.863404633 RPC10 subunit of RNA polymerase II YHR144C 1.566484148 0.204399121 -0.200260543 0.203614485 DCD1 dCMP deaminase YHR145C 0.372578731 0.344489224 0.120178946 0.078624647 questionable ORF YHR146W -0.29330386 0.050712166 -0.667000859 0.03149637 similarity to pheromone-response G-protein Mdg1p YHR147C 0.292750068 0.343685993 -0.13544817 0.19026596 MRPL6 Mitochondrial ribosomal protein MRPL6 (YmL6) YHR148W 1.10051973 0.026877946 -0.269970169 0.399239485 IMP3 ribosomal protein (weak similarity) YHR149C 0.584497301 0.102466938 0.023976948 0.789586532 similarity to hypothetical protein YGR221c YHR151C 0.169863702 0.519689018 0.238598494 0.205221745 hypothetical protein 20 kDa protein with negatively charged C-terminus required for function ; thought to be a positive regulator of exit from M-phase in mitosis and YHR152W -0.01883398 0.904353101 -0.195837058 0.425205464 SPO12 meiosis. Spo12p interacts with Dbf2p and Dbf20p protein kinases. YHR153C -0.16959163 0.496560982 0.231183174 0.004594551 SPO16 sporulation protein YHR154W 0.433065842 0.197242677 -0.170183052 0.572236021 ESC4 involved in silencing YHR155W -0.23049358 0.2660326 0.009450714 0.870607498 Snf1-interacting protein Sip3p YHR156C 0.612122357 0.38372208 -0.297845476 0.2448325 weak similarity to mouse kinesin KIF3B YHR157W -0.01648238 0.980415337 0.356562536 0.412953595 REC104 mRNA is induced early in meiosis YHR158C -0.19341009 0.586542104 -0.003894349 0.974714735 KEL1 involved in cell fusion and morphology ; contains six Kelch repeats YHR159W -0.64544645 0.002801864 -0.19090303 0.257023399 hypothetical protein YHR160C -0.44643654 0.316054456 0.206848452 0.219147546 PEX18 Peroxin Pex18p YHR161C -0.20135642 0.595362151 0.230473329 0.071370154 YAP1801 clathrin assembly protein YHR162W 1.298133308 0.029000323 0.242149655 0.035099721 strong similarity to hypothetical protein YGR243w YHR163W 1.262319154 0.306916372 0.251153613 0.108962714 SOL3 shows similarity to glucose-6-phosphate dehydrogenase non-catalytic domains ; homologous to Sol2p and Sol1p YHR166C -0.11002653 0.704471525 -0.289240226 0.13391981 CDC23 Cell division cycle protein YHR167W 0.441589925 0.256848447 -0.447390751 0.049732556 hypothetical protein YHR168W -0.54858136 0.041153137 -0.09395572 0.237406632 GTP-binding protein YHR169W 1.071023322 0.026341381 -0.052940909 0.73277128 DBP8 DEAD-box protein YHR170W 1.149229672 0.06563694 -0.274778166 0.185176879 NMD3 cytoplasmic factor required for a late cytoplasmic assembly step of the 60S subunit YHR171W -0.9865548 0.041410971 -0.156756234 0.104952879 APG7 similar to ubiquitin-activating enzymes, involved in autophagy YHR172W 0.565156624 0.207692328 0.315992596 0.151787532 SPC97 spindle pole body component, associates in a complex with Spc98p and Tub4p perhaps as part of the microtubule attachment site of the SBP YHR173C 0.395659129 0.332106741 0.64869922 0.049053595 YHR174W -0.09773865 0.81203759 0.38643507 0.161464467 ENO2 enolase YHR175W -0.10090145 0.708685104 0.335355267 0.118950333 CTR2 copper transporter YHR176W -0.93665307 0.05271515 -0.001520971 0.971887034 FMO Dimethylaniline monoxygenase YHR177W -0.10878464 0.735157407 0.113161025 0.189471322 hypothetical protein YHR178W -0.13233263 0.539553767 0.073912083 0.055042398 STB5 Zinc finger (6-Cys) YHR179W 1.21204097 0.05912328 0.142390634 0.233966001 OYE2 NAPDH dehydrogenase (old yellow enzyme), isoform 2 YHR180W -0.54804587 0.055290141 0.320387705 0.174835092 hypothetical protein YHR181W 0.520305948 0.024205744 0.68612666 0.044860772 similarity to mouse TEG-261 protein YHR182W -0.40614112 0.305893378 -0.036561851 0.822805533 hypothetical protein YHR183W 1.038341297 0.409122011 0.37344342 0.245342797 GND1 Phosphogluconate Dehydrogenase (Decarboxylating) YHR184W -1.70612433 0.001502293 -0.490917239 0.017619383 SSP1 involved in meiosis, nuclear division and spore formation YHR185C 0.166921392 0.800306594 0.120073277 0.502741733 ADY1 (putative) involved in meiosis YHR186C -0.24345021 0.164814702 0.013028668 0.851036889 similarity to C.elegans hypothetical protein C10C5.6 YHR187W 0.063654797 0.652567706 -0.190930922 0.084309329 IKI1 involved in sensitivity to pGKL killer toxin YHR188C -0.49831124 0.131344396 0.764773577 0.021780812 similarity to hypothetical C. elegans proteins F17c11.7 YHR189W -0.25221721 0.493684844 0.403145448 0.10232142 similarity to peptidyl-tRNA hydrolases YHR190W -0.10191439 0.618185574 0.220185479 0.054227583 ERG9 squalene synthetase YHR191C 0.526989588 0.007199883 0.273177293 0.007378805 CTF8 (putative) kinetochore protein YHR192W -0.03320415 0.689616679 -0.075368759 0.335939938 hypothetical protein YHR193C 0.64444792 0.042873528 0.297232313 0.099778173 EGD2 GAL4 enhancer protein, homolog of human alpha NAC subunit of the nascent-polypeptide-associated complex YHR194W -0.46188026 0.179817358 0.176756556 0.310017326 similarity to hypothetical protein YOR147w YHR195W -0.10231317 0.58444096 -0.436870368 0.040478026 NVJ1 Vac8p binding protein ; nucleus-vacuole junction YHR196W 0.899712809 0.196434291 -0.884708707 0.060006891 hypothetical protein YHR197W 0.889286837 0.110947379 -0.274387708 0.180804135 hypothetical protein YHR198C -0.65878703 0.004797093 0.104031701 0.386507865 strong similarity to hypothetical protein YHR199c YHR199C -0.11046916 0.789742707 0.376926074 0.033499469 strong similarity to hypothetical protein YHR198c YHR200W 0.052933961 0.738562943 0.276110534 0.295463438 RPN10 homolog of the mammalian S5a protein, component of 26S proteasome YHR201C 0.802711026 0.079264839 -0.049502495 0.692184354 PPX1 Cytosolic exopolyphosphatase YHR202W -1.26728247 0.005314423 0.072078089 0.188463507 similarity to S.pombe hypothetical protein SPAC17G6 YHR203C 1.426400066 0.003420178 0.455713295 0.040050033 RPS4B Ribosomal protein S4B (YS6) (rp5) (S7B) YHR204W 0.83568021 0.113108803 0.580345165 0.026553757 HTM1 degradation lectin YHR205W -0.34979531 0.392392328 0.353612158 0.220941105 SCH9 cAMP-dependent protein kinase homolog, suppressor of cdc25ts YHR206W 0.445342993 0.098329703 0.193416854 0.057927714 SKN7 transcription factor involved in oxidative stress response YHR207C 0.230093423 0.368648488 -0.48239663 0.171488573 weak similarity to YPL165c YHR208W 1.219136266 0.091252877 0.172069854 0.036984466 BAT1 branched-chain amino acid transaminase, highly similar to mammalian ECA39, which is regulated by the oncogene myc YHR209W 0.488329364 0.3400545 -0.262077561 0.039905244 putative methyltransferase YHR210C -0.10793441 0.63365572 -0.017744512 0.820329908 UDP-glucose-4-epimerase (GAL10, galE) YHR211W -0.39892233 0.343156205 0.61032881 0.134690503 FLO5 Flocculin, similar to flocculation protein Flo1p YHR212C 0.401484347 0.393313373 -0.193979962 0.411995133 identical with hypothetical protein YAR060c YHR213W 0.133670902 0.508405928 0.364254039 0.268759284 putative pseudogene YHR214C-C 1.025116718 0.200272452 0.490696775 0.029564393 TyA gag protein. Gag processing produces capsid proteins. YHR214W 0.5392961 0.322789773 0.515055442 0.09269564 identical to YAR066w hypothetical protein, similarity to Sta1p YHR214W-A 0.223120952 0.476039421 0.772410171 0.106047437 strong similarity to hypothetical protein YAR068w YHR215W -0.55718205 0.292696166 0.491153679 0.138003756 PHO12 Acid phosphatase, nearly identical to Pho11p YHR216W 0.820397275 0.094455733 0.054133861 0.690255067 IMD2 IMP dehydrogenase ; probable PUR5 gene YHR217C -0.00505134 0.989208831 0.74024248 0.006702785 strong similarity to subtelomeric encoded YDR544c YHR218W -0.97151712 0.021241896 0.397253915 0.256384155 strong similarity to subtelomeric encoded proteins /gene in Y' repeat region YHR219W -1.1512685 0.016474946 0.441073979 0.156187602 strong similarity to other subtelomeric encoded proteins YIL001W -0.09160555 0.673382508 0.075883051 0.153053555 similarity to S.pombe hypothetical protein, weak similarity to human ankyrin YIL002C 0.216905266 0.614172566 -0.107933116 0.063512218 INP51 phosphatidylinositol 4,5-bisphosphate 5-phosphatase YIL003W -0.13517256 0.373316219 -0.096642683 0.217327519 strong similarity to Nbp35p and human nucleotide-binding protein YIL004C 0.417493426 0.038146388 -0.04701578 0.485994482 BET1 involved in ER-Golgi transport YIL005W -0.009214 0.970204909 0.220948032 0.221412247 similarity to protein disulfide isomerases YIL006W -0.42056772 0.343622299 0.648233692 0.086907398 similarity to Flx1p YIL007C -0.29258931 0.082183337 -0.022994642 0.767619607 similarity to C.elegans hypothetical protein YIL008W 1.503221928 0.109604288 -0.157022249 0.623349975 URM1 ubiquitin related modifier YIL009C-A -0.07209557 0.541527057 0.272867235 0.102120249 EST3 181aa protein - 20.5 kD YIL009W -0.68262418 0.057182335 0.032295888 0.561233369 FAA3 Acyl CoA synthase YIL010W -0.35570308 0.02731422 0.045339424 0.697402541 DOT5 involved in telomeric silencing YIL011W 1.064165148 0.174296051 0.330089098 0.333459752 strong similarity to members of the Srp1p/Tip1p family YIL012W -0.62157446 0.089298272 1.137185686 0.417861958 hypothetical protein YIL013C -0.22309105 0.018103151 0.515075812 0.075017314 PDR11 Putative member of the ABC family of membrane transporters YIL014W 0.180717919 0.420730504 -0.082273187 0.285228026 MNT3 alpha-1,3-mannosyltransferase YIL015C-A -0.52734748 0.110547586 0.186216821 0.486660799 YIL016W -0.08189779 0.765268414 -0.072442021 0.484504346 SNL1 18.3 kD integral membrane protein YIL017C -0.95728696 0.00991492 0.309775995 0.143451376 VID28 vacuole import and degradation YIL018W 2.978587365 0.194555902 0.507191111 0.161837926 RPL2B Ribosomal protein L2B (L5B) (rp8) (YL6) YIL019W 0.365084504 0.563447405 -0.726673622 0.047063315 weak similarity to S.pombe hypothetical protein SPAC3F10 YIL020C 0.507458006 0.158607466 0.131135898 0.032119514 HIS6 phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide isomerase YIL021W 0.37473562 0.094761099 -0.24503253 0.188496848 RPB3 45 kDa subunit of RNA polymerase II YIL022W 0.321725728 0.422791035 0.102583907 0.49877391 TIM44 48.8 kDa protein involved in mitochondrial protein import YIL023C 0.657581748 0.033591145 0.407268041 0.066475592 similarity to mouse MHC H-2K/t-w5-linked ORF precursor YIL024C -1.47183789 0.006904432 0.597774602 0.149837655 hypothetical protein YIL025C -0.28734184 0.607419172 0.097648544 0.841360747 weak similarity to E.gracilis RNA polymerase subunit YIL026C 0.079762062 0.677406151 -0.211784831 0.106556966 IRR1 Irregular//essential protein YIL027C 0.535676333 0.284133926 -0.174712082 0.317328666 hypothetical protein YIL028W -0.06030142 0.913912323 0.008594349 0.976775911 hypothetical protein YIL029C -0.26283521 0.24382912 -0.364091086 0.022936136 YIL031W -0.47818984 0.132074531 -0.213563506 0.157902702 ULP2 Smt3p-specific protease, degrades conjugated ubiquitin-like protein Smt3p YIL032C 0.104453996 0.784218652 -0.193229339 0.006721346 hypothetical protein YIL033C -0.8888344 0.006188575 0.402662481 0.222131195 BCY1 regulatory subunit of cAMP-dependent protein kinase YIL034C -0.27523524 0.008340894 0.662014564 0.054747832 CAP2 beta subunit of capping protein YIL035C 0.795058141 0.024517162 -0.491832062 0.077338642 CKA1 alpha subunit of casein kinase II YIL036W -0.46758394 0.026899964 0.228915995 0.048803033 CST6 omosome STability YIL037C -0.21928666 0.267181985 0.085190283 0.586339372 PRM2 pheromone-regulated membrane protein YIL038C -0.01231968 0.962751811 -0.462448882 0.089251299 NOT3 CCR4 trascriptional complex component YIL039W -0.24388481 0.54394423 0.296573407 0.109410433 hypothetical protein YIL040W 1.57923939 0.15359519 0.845833391 0.017631627 weak similarity to T.brucei NADH dehydrogenase YIL041W -0.05740829 0.790704385 0.527544501 0.068299482 similarity to S.pombe hypothetical protein YIL042C -0.74856486 0.085638333 0.349160592 0.242207012 similarity to rat branched-chain alpha-ketoacid dehydrogenase kinase YIL043C 0.146635478 0.243741968 0.444139975 0.042153734 CBR1 cytochrome b reductase YIL044C 0.375135001 0.44209613 -0.159926883 0.40538758 AGE2 ARF GAP with effector function(s) YIL045W -2.14883841 0.001395234 -0.477118562 0.030036605 PIG2 Protein with 30 % identity to protein corresponding to YER054 YIL046W -0.89447966 0.030549911 0.25300586 0.321801754 MET30 Met30p contains five copies of WD40 motif and interacts with and regulates Met4p YIL047C 0.05393996 0.352422675 0.537037953 0.047984161 SYG1 plasma membrane protein YIL048W 0.191602792 0.294666605 0.137810603 0.134065562 NEO1 P-Type ATPase YIL049W 0.656603842 0.13863485 0.577686739 0.108509341 DFG10 involved in filamentous growth YIL050W -0.62671141 0.052497278 0.062650935 0.135706755 PCL7 PHO85 cyclin YIL051C 0.392512902 0.062559692 0.776044876 0.045849346 MMD1 Maintenance of Mitochondrial DNA 1 YIL052C 1.135289748 0.044008456 0.35202333 0.146665611 RPL34B Ribosomal protein L34B YIL053W 0.829574508 0.101822061 0.033085833 0.88166581 RHR2 DL-glycerol-3-phosphatase YIL054W -0.34314481 0.514199581 0.670285915 0.551443934 weak similarity to fruit fly NADH dehydrogenase YIL055C -0.7953206 0.093870175 0.348430803 0.258182438 hypothetical protein YIL057C -0.45630569 0.359882424 0.1260716 0.422649731 strong similarity to YER067w YIL058W -0.15784162 0.630258117 0.283257275 0.07749864 hypothetical protein YIL059C -1.01642298 0.007585394 0.179668494 0.066584901 hypothetical protein YIL060W -0.14232829 0.570195751 0.060180052 0.590928297 questionable ORF YIL061C 0.104021078 0.705839133 0.243085237 0.219642015 SNP1 U1snRNP 70K protein homolog YIL062C -0.18386936 0.406449306 0.369171539 0.027763816 ARC15 ARP2 /3 complex component YIL063C -0.20466469 0.378448935 -0.63945988 0.156977128 YRB2 nuclear protein, interacts with Gsp1p and Crm1p YIL064W -0.40489333 0.208185933 0.064589705 0.496770016 putative methyltransferase YIL065C -0.71229279 0.036194177 0.144161277 0.158889403 FIS1 mitochondrial fission YIL066C -0.7769214 0.113459848 0.389666668 0.070885608 RNR3 Ribonucleotide reductase (ribonucleoside-diphosphate reductase) large subunit YIL067C 0.387900958 0.355194717 0.11608919 0.309875893 hypothetical protein 88 kD component of the Exocyst complex, which contains the gene products encoded by SEC3, SEC5, SEC6, SEC8, SEC10, SEC15 and YIL068C -0.14312897 0.048530054 -0.619414513 0.034908361 SEC6 EXO70 YIL069C 1.146720758 0.044086876 -0.070902167 0.675752713 RPS24B 40S ribosomal protein S24B YIL070C 0.7474478 0.150008052 -0.131640019 0.217439817 MAM33 Mitochondrial protein involved in respiration YIL072W -0.93432663 0.006438583 0.223829037 0.439788909 HOP1 DNA binding protein YIL073C -0.07103993 0.734230144 -0.041316668 0.812464831 SPO22 meiosis-specific phospholipase A2 homolog YIL074C -0.10118791 0.672165896 0.056414171 0.180743273 SER33 3-phosphoglycerate dehydrogenase YIL075C 0.335898048 0.210415146 -0.123071298 0.166030805 RPN2 RPN2p is a component of the 26S proteosome YIL076W 0.533368933 0.44998696 -0.427882379 0.13967927 SEC28 epsilon-COP coatomer subunit Sec28p YIL077C -0.57725151 0.060554411 0.010967974 0.908212038 hypothetical protein YIL078W 0.872746115 0.053601611 -0.233308757 0.165740371 THS1 Threonyl-tRNA synthetase, cytoplasmic YIL079C 1.642098321 0.234191627 -0.516342137 0.096996009 strong similarity to hypothetical protein YDL175c Ty3B Gag-Pol protein. Gag processing produces capsid proteins. Pol is cleaved to produce protease, reverse transcriptase and integrase YIL080W -0.18904764 0.718836182 0.042235352 0.83171438 activities. YIL082W -0.31473501 0.156976617 0.03388795 0.829234936 TY3A protein YIL083C -0.73045057 0.007137924 -0.060480044 0.546384977 hypothetical protein YIL084C -0.11786036 0.767712681 0.117091205 0.342522391 SDS3 Functions are similar to those of SIN3 and RPD3/(putative) transcriptional regulator YIL085C -0.68578997 0.009924702 -0.066727987 0.478416763 KTR7 (putative) mannosyltransferase YIL086C -0.35990359 0.359428625 0.28163798 0.388132575 hypothetical protein YIL087C -0.95582344 0.026860307 0.941411462 0.122407896 hypothetical protein YIL088C 0.011628331 0.984335157 0.144612195 0.385662238 similar to amino acid transport proteins YIL089W -1.03223128 0.00161743 -0.095838044 0.495466297 similarity to hypothetical protein YLR036c YIL090W -0.25265757 0.345146238 0.111303049 0.164228963 similarity to hypothetical S. pombe protein YIL091C 0.952844868 0.012734456 -0.587183716 0.060538025 weak similarity to spt5p YIL092W 0.457547672 0.056134011 -0.364426032 0.01013772 hypothetical protein YIL093C 0.308817303 0.223126172 -0.045758193 0.137822968 RSM25 protein of the small subunit of the mitochondrial ribosome YIL094C 3.01154943 0.233079348 -0.330494911 0.032889955 LYS12 Homo-isocitrate dehydrogenase YIL095W 0.991069255 0.122252277 -0.03908687 0.615700752 PRK1 probable serine /threonine-protein kinase YIL096C 0.350053859 0.421074918 -0.794879392 0.045877958 hypothetical protein YIL097W -1.00693506 0.004216961 -0.61968221 0.037443579 hypothetical protein YIL098C -0.00269308 0.986769775 -0.609444217 0.078544153 FMC1 Formation of Mitochondrial Cytochromes 1 YIL099W -0.83453916 0.017299127 0.056309722 0.679124453 SGA1 intracellular glucoamylase YIL100W 0.279275753 0.424971528 0.524041605 0.091460614 similarity to mouse Gcap1 protein and fruit fly Bkm-like sex-determining region hypothetical YIL101C -0.71155455 0.218567243 0.461411213 0.119611025 XBP1 transcriptional repressor YIL102C 0.47934189 0.178626794 0.139095502 0.276765443 strong similarity to YIL014c-a YIL103W 0.525849445 0.221349187 -0.23143496 0.085844787 weak similarity to Dph2 protein YIL104C 0.423386507 0.036063909 -0.51538229 0.068132026 similarity to hypothetical S. pombe protein YIL105C -0.22638526 0.434311443 -0.370811269 0.026982314 weak similarity to probable transcription factor Ask10p YIL106W 0.678201223 0.029279814 0.205400858 0.428318923 MOB1 required for completion of mitosis and maintenance of ploidy /(putative) transcriptional regulator involved in mitosis YIL107C -0.78055 0.008997496 -0.333213644 0.147691874 PFK26 6-Phosphofructose-2-kinase YIL108W 0.121721916 0.491115493 0.346934239 0.066433743 similarity to hypothetical S. pombe protein YIL109C 0.225821452 0.679128241 0.464963928 0.006775498 SEC24 vesicle coat component YIL110W 0.201982042 0.603798713 -0.361079728 0.174167305 weak similarity to hypothetical C.elegans protein YIL111W 0.633350526 0.501976381 0.005507092 0.952886892 COX5B Cytochrome-c oxidase chain Vb YIL113W -1.38486426 0.004289748 -0.055777469 0.769007829 strong similarity to dual-specificity phosphatase Msg5p YIL114C 0.912503634 0.135480833 0.404241521 0.138673789 POR2 voltage dependent anion channel (YVDAC2) YIL115C -0.34718902 0.247472894 0.504168517 0.01499191 NUP159 159-kDa nucleoporin with coiled-coil domain and repeated motifs typical of nucleoporins YIL116W 0.187514462 0.674545131 -0.277233319 0.033555323 HIS5 histidinol-phosphate aminotransferase YIL117C 1.516940798 0.101375043 0.024926305 0.713797972 PRM5 hydrophobic transmembrane domain YIL118W 1.630968052 0.311394613 -0.22242045 0.274533916 RHO3 ras homolog--GTP binding protein YIL119C -1.24456463 0.048925774 -0.215637091 0.218553701 RPI1 inhibitor of ras YIL120W -1.56654126 0.002770402 -0.164024484 0.106609859 QDR1 MFS-MDR transporter YIL121W -0.00428032 0.977260137 0.363198331 0.045896467 similarity to antibiotic resistance proteins YIL122W -0.22022657 0.502705613 -0.036221751 0.795080178 similarity to antibiotic resistance proteins YIL123W 1.2710086 0.090769252 0.699773202 0.142491472 SIM1 (putative) invovled in control of DNA replication YIL124W -1.32666417 0.012304222 0.118509643 0.501518912 AYR1 1-Acyl dihydroxyacetone phosphate reductase YIL125W -1.35271825 0.004771046 0.375908348 0.171727046 KGD1 alpha-ketoglutarate dehydrogenase YIL127C 1.213314274 0.130083755 -0.723337855 0.096055624 weak similarity to Smy2p YIL128W 0.141887024 0.215537607 -0.149046895 0.195491511 MET18 regulator of TFIIH YIL131C 0.314151795 0.321259856 -0.095199964 0.630920249 FKH1 similarity to Drosophila fork head protein YIL132C 0.301458398 0.642493622 0.687817474 0.305285524 hypothetical protein YIL133C 1.094185355 0.015515901 0.329241219 0.020929948 RPL16A Ribosomal protein L16A (L21A) (rp22) (YL15) YIL134W 0.671914603 0.18595626 0.051956652 0.532000582 FLX1 mitochondrial inner membrane carrier protein for FAD YIL135C -0.21397154 0.464123132 0.556900759 0.097805567 similarity to Ymk1p YIL136W -1.81957216 0.006287962 -0.060663157 0.43986106 OM45 45-kDa mitochondrial outer membrane protein YIL137C -0.67189853 0.133407013 0.406151013 0.006377825 similarity to M.musculus aminopeptidase YIL138C 0.304733749 0.688703052 -1.020463738 0.011617351 TPM2 Tropomyosin isoform 2 YIL139C -0.22339426 0.324760866 -0.614911729 0.008093686 REV7 subunit of DNA polymerase-zeta (Pol-zeta), an enzyme whose sole function appears to be translesion synthesis YIL140W 1.747844295 0.066504228 0.64613776 0.185687898 AXL2 localizes to the plasma membrane YIL141W 1.197171674 0.09845512 0.525965435 0.223980348 questionable ORF YIL142W 0.667109452 0.172211264 0.366350601 0.127315837 CCT2 molecular chaperone YIL143C -0.09025988 0.604993148 -0.076993423 0.028109726 SSL2 DNA helicase homolog ; homolog of human XPBC, ERCC3 YIL144W 0.179428483 0.133567324 -0.814318943 0.042024179 TID3 Dmc1p interacting protein YIL145C 0.364074042 0.03246804 0.151606076 0.010242307 similarity to E.coli pantothenate synthetase YIL146C -1.2181541 0.004935778 0.027172842 0.76640703 ECM37 (putative) involved in cell wall biogenesis YIL149C 0.845436256 0.0682367 -0.428962907 0.045532108 MLP2 colied-coil protein (putative), similar to myosin and TPR YIL150C 0.108193507 0.642209734 -0.115366506 0.167387088 DNA43 (putative) involved in DNA replication YIL151C -0.38543849 0.078948777 -0.017097204 0.868237288 similarity to mitochondrial aldehyde dehydrogenase Ald1p YIL152W -0.29441563 0.178204527 0.173469074 0.004380275 hypothetical protein YIL153W -0.18469247 0.643742147 0.218527938 0.360592048 RRD1 Resistant to Rapamycin Deletion YIL154C 0.00685458 0.975494534 0.165754479 0.654403423 IMP2' transcription factor YIL155C -1.48882 0.008626493 0.456554154 0.085452526 GUT2 glycerol-3-phosphate dehydrogenase, mitochondrial YIL156W -0.7329803 0.036774182 0.200903459 0.382964222 UBP7 Ubiquitin-specific protease YIL157C 0.388819748 0.25816604 0.101496801 0.25704905 identified by SAGE expression analysis YIL158W 1.191930699 0.150059973 0.088574221 0.714964311 similarity to hypothetical protein YKR100c YIL159W -0.01157307 0.943965221 -0.055205391 0.830222974 BNR1 involved in actin filament organization YIL160C -0.79486803 0.210981007 0.432490744 0.240313753 POT1 peroxisomal 3-oxoacyl CoA thiolase YIL161W 0.512315747 0.073225422 -0.66291942 0.087927376 hypothetical protein YIL162W -1.08807063 0.012858199 0.246809872 0.092944469 SUC2 invertase (sucrose hydrolyzing enzyme) YIL163C -0.15042267 0.788899474 0.554037248 0.180449113 questionable ORF YIL164C 0.647161707 0.54740727 -0.163427552 0.145142981 NIT1 nitrilase YIL165C 1.073039522 0.384520837 0.222326888 0.353569934 putative pseudogene YIL166C -0.02919736 0.929191679 0.035971753 0.476785226 similarity to allantoate permease Dal5p YIL167W -0.15843803 0.660513267 -0.608026203 0.009096417 SDL1 serine dehydratase YIL168W -0.09092528 0.603457041 -0.073402226 0.765782405 SDL1 L-serine dehydratase YIL170W -0.95345352 0.023312834 0.393807286 0.300195604 HXT12 hexose permease YIL171W -0.18245219 0.523793688 0.518047926 0.255157617 HXT12 hexose permease YIL172C -1.35332777 0.005467206 -0.043264041 0.342901546 putative alpha glucosidase YIL173W 0.619774167 0.188374389 0.318155161 0.12910954 VTH1 potential membrane glycoprotein with strong similarity to Vth2 and Pep1 /Vps10 YIL174W -0.46645481 0.222167691 0.175861892 0.554220257 strong similarity to subtelomeric encoded proteins YIL175W -0.60386905 0.085415673 0.200205238 0.483513883 strong similarity to subtelomeric encoded proteins YIL176C -0.17742989 0.329223104 0.922850732 0.197739729 strong similarity to members of the Srp1p/Tip1p family YIR001C -0.18817803 0.041862692 -0.151161549 0.231137278 SGN1 Contains one RNA recognition (RRM) domain YIR002C -0.03016125 0.448496418 -0.401096038 0.010992559 MPH1 Mutator PHenotype ; Similar to ATP-dependent RNA helicases YIR003W -0.67893828 0.101841296 -0.280221623 0.273200418 weak similarity to mammalian neurofilament triplet H proteins YIR004W 0.466530259 0.225810731 -0.689953563 0.055944257 DJP1 involved in peroxisome biogenesis YIR005W -0.44489071 0.03834615 -0.912755582 0.039362456 IST3 similarity to RNA-binding proteins YIR007W -0.18404978 0.426107601 0.504928242 0.1820264 hypothetical protein YIR008C -0.00023744 0.999054932 -0.159501298 0.172093617 PRI1 p48 polypeptide of DNA primase YIR009W 0.607059162 0.054314767 0.0764621 0.802061076 MSL1 encodes YU2B, a component of yeast U2 snRNP YIR010W -0.19829331 0.3810131 -0.82561633 0.153739486 hypothetical protein YIR011C 0.744415504 0.008527846 -0.489595303 0.057582501 STS1 (putative) involved in control rRNA stability and protein transport YIR012W 1.857604084 0.134842258 -0.029324245 0.521243634 SQT1 contains multiple WD repeats and interacts with Qsr1p in two hybrid YIR013C -0.28339705 0.376788224 0.08880927 0.70361908 GAT4 very short and so far mRNA can't be detected YIR014W -0.90250004 0.02087956 -0.038420201 0.822649841 hypothetical protein YIR015W -0.14372826 0.770216971 0.22147769 0.402499568 RPR2 an integral subunit of RNase P but not RNase MRP YIR016W -0.95807034 0.011739989 0.422492836 0.398167002 weak similarity to YOL036w YIR017C -1.13956598 0.011237914 -0.108940563 0.184020006 MET28 transcriptional activator in the Cbf1p-Met4p-Met28p complex YIR018W -0.66381875 0.044497635 -0.005519473 0.94586291 YAP5 bZIP transcription factor YIR019C -0.14895823 0.674664293 0.997563654 0.044401356 MUC1 cell surface flocculin with structure similar to serine /threonine-rich GPI-anchored cell wall proteins YIR020C -0.84619489 0.024618852 0.449515198 0.238695179 hypothetical protein YIR021W 0.941688963 0.160787558 0.202251409 0.088498555 MRS1 mitochondrial RNA splicing YIR022W 0.432585353 0.047712877 0.417169917 0.050341754 SEC11 signal peptidase subunit YIR024C -0.16337098 0.618675063 -0.536183208 0.063264647 GIF1 (putative) involved in cell cycle control YIR025W -0.23491922 0.046811133 -0.109305824 0.521714492 hypothetical protein YIR026C 0.215410563 0.38469696 0.149715476 0.211536759 YVH1 nitrogen starvation-induced protein phosphatase YIR027C -0.7207958 0.178425973 0.29182961 0.013759536 DAL1 allantoinase YIR028W 0.115912662 0.802957301 0.160982931 0.520379069 DAL4 allantoin permease YIR029W -1.42219503 0.015620483 0.03705494 0.880731259 DAL2 allantoicase YIR030C -0.73104683 0.111679678 -0.47221861 0.049293707 DCG1 involved in nitrogen-catabolite metabolism YIR031C 0.903422622 0.535100925 -0.064357795 0.210286806 DAL7 Malate synthase 2 YIR032C -0.22076902 0.769578002 -0.037766984 0.838935783 DAL3 ureidoglycolate hydrolase YIR033W 0.608811868 0.186794166 -0.336126284 0.003249096 MGA2 may be involved in the remodeling chromatin structure YIR034C 4.251063246 0.195216284 0.510901494 0.132541784 LYS1 saccharopine dehydrogenase YIR035C 0.227704484 0.510663812 0.285782581 0.246611886 similarity to human corticosteroid 11-beta-dehydrogenase YIR036C -1.33757731 0.004258673 0.207345324 0.476502162 similarity to E.coli fabD YIR037W -1.09991182 0.003641536 0.442453544 0.188386072 HYR1 putative glutathione-peroxidase YIR038C -1.33525548 0.001507542 0.143023251 0.310028051 GTT1 Glutathione transferase YIR039C -0.78134911 0.059956416 0.106882839 0.522127631 YPS6 GPI-anchored aspartic protease YIR040C -0.71026221 0.096020525 0.135481416 0.480759488 strong similarity to subtelomeric encoded proteins YIR041W -0.31151923 0.110790615 0.5667012 0.028240598 similarity to members of the Srp1p/Tip1p family YIR042C -0.20542659 0.679170995 -0.71617391 0.000798361 weak similarity to B.licheniformi hypothetical protein P20 YIR043C -0.12918371 0.734926827 -0.213166333 0.313802586 strong similarity to family of COnserved Sequences COS YIR044C -0.10290154 0.81219307 0.081992648 0.542099952 strong similarity to family of COnserved Sequences COS YJL001W -0.02949041 0.90587783 -0.078201106 0.625860745 PRE3 Subunit of 20S proteasome YJL002C 0.735296874 0.280540166 0.666319541 0.101758278 OST1 64-kDa, alpha subunit of oligosaccharyltransferase complex ; homologous to mammalian ribophorin I YJL003W -0.22160675 0.238823886 -0.343683409 0.061279341 hypothetical protein YJL004C -0.09484277 0.491608377 -0.104505398 0.14927612 SYS1 Multicopy suppressor of ypt6 null mutation YJL006C -0.2082421 0.407495617 -0.181671328 0.229552098 CTK2 cyclin-like protein YJL007C -0.35654833 0.326950598 0.795578605 0.352319679 hypothetical protein YJL008C 0.389455301 0.178793397 -0.25125483 0.000514349 CCT8 Component of Chaperonin Containing T-complex subunit eight YJL009W 0.862530422 0.018033748 0.115909365 0.57115631 questionable ORF YJL010C 0.591406624 0.236781786 -0.494397726 0.071391862 weak similarity to C.elegans hypothetical protei ZK792.5 YJL011C 1.065633675 0.094651179 -0.333065417 0.162483737 weak similarity to chicken hypothetical protein YJL012C -0.38418281 0.560673419 -0.171215067 0.063939506 VTC4 polyphosphate synthetase (putative) YJL013C 0.323768838 0.122543013 -0.187692715 0.31655206 MAD3 spindle checkpoint complex subunit YJL014W 0.520967516 0.085221983 -0.122296449 0.093473542 CCT3 Cytoplasmic chaperonin subunit gamma YJL015C -0.41483993 0.020227539 0.374666887 0.314153478 questionable ORF YJL016W -0.6191085 0.032587254 0.110452221 0.609787021 weak similarity to hypothetical protein YNL278w and YLR187w YJL017W -0.66796477 0.031729448 -0.127998537 0.409049191 hypothetical protein YJL018W 0.022252911 0.925072395 0.33782487 0.040502915 questionable ORF YJL019W -0.16422617 0.694252774 -0.186538122 0.095664897 hypothetical protein YJL020C -1.08369838 0.01400947 0.075080582 0.258728548 similarity to P.falciparum glutamic acid-rich protein YJL022W -0.51727024 0.056366592 -0.002058405 0.989215536 questionable ORF YJL023C -0.4132773 0.280632097 -0.061325612 0.755620119 PET130 Nuclear gene encoding mitochondrial protein YJL024C 0.48062177 0.007748129 0.151262733 0.424022955 APS3 similar to Aps1p and mammalian small subunit (sigma-2 adaptin) of plasma membrane-associated clathrin assembly complex (AP-2) YJL025W 0.714167517 0.078394469 0.423103629 0.005423333 RRN7 member of yeast Pol I core factor (CF) also composed of Rrn11p, Rrn6p and TATA-binding protein YJL026W -0.47847276 0.10662536 0.543492237 0.160303541 RNR2 small subunit of ribonucleotide reductase YJL027C 0.200249844 0.659395685 0.597847829 0.412241979 hypothetical protein YJL028W 0.377432625 0.264666074 0.411291985 0.091169783 hypothetical protein YJL029C -0.02111419 0.747618548 0.104672432 0.518428028 VPS53 Vps53p is a hydrophilic protein that is peripherally associated with the late Golgi and forms a stable complex with Vps52p and Vps54p. YJL030W 0.092033147 0.804559144 -0.234675164 0.15600943 MAD2 spindle checkpoint complex subunit YJL031C 0.232029394 0.217041562 -0.720298355 0.022913908 BET4 Geranylgeranyltransferase Type II alpha subunit (PGGTase-II, alpha subunit) YJL032W 0.45457029 0.063300733 -0.252000045 0.005149723 questionable ORF YJL033W 0.477595382 0.207597439 -0.666317875 0.047958521 HCA4 putative RNA helicase YJL034W -0.58361615 0.140919055 0.060029871 0.720790229 KAR2 Homologue of mammalian BiP (GPR78) protein ; member of the HSP70 gene family YJL035C 0.616925081 0.293925517 -0.06031783 0.470437189 TAD2 tRNA-specific adenosine-34 deaminase subunit Tad2p YJL036W -0.26843652 0.114094945 -0.462049062 0.0209533 SNX4 Sorting NeXin YJL037W -0.86952447 0.063480579 0.242176028 0.512317479 strong similarity to hypothetical protein YJL038c YJL038C -0.16089034 0.588840437 0.505550241 0.3603331 strong similarity to hypothetical protein YJL037w YJL039C 0.013301016 0.938013586 -0.018088515 0.756736938 NUP192 large yeast nucleoporin YJL041W -0.28998946 0.179460904 0.233170519 0.219594726 NSP1 nuclear pore protein YJL042W -1.3054657 0.011000511 0.782416155 0.06299027 MHP1 Putative microtubule-associated protein (MAP) YJL043W -0.33244615 0.190412378 -0.094280437 0.470840627 similarity to hypothetical protein YKR015c YJL044C -0.37412457 0.069572339 -0.254549608 0.007651679 GYP6 GTPase-activating protein for Ypt6 YJL045W -0.72600801 0.179914258 0.024110435 0.900701261 strong similarity to succinate dehydrogenase flavoprotein YJL046W 0.317353578 0.175696541 0.10075472 0.530687083 similarity to E.coli lipoate-protein ligase A YJL047C -0.39602593 0.226897941 -0.279001232 0.006710743 RTT101 Regulator of Ty1 Transposition YJL048C -0.63843368 0.277413691 0.108175243 0.416022324 similarity to hypothetical protein YBR273c YJL049W -0.34200786 0.201016266 -1.091567962 0.02722376 hypothetical protein YJL050W 0.918190007 0.084112815 -0.389186482 0.15044737 MTR4 RNA helicase YJL051W -0.91850488 0.018503121 0.212560001 0.181831653 hypothetical protein YJL052W -0.91132411 0.005133797 0.658589263 0.233421705 TDH1 Glyceraldehyde-3-phosphate dehydrogenase 1 YJL053W -0.22142225 0.435965259 -0.181215628 0.344475603 PEP8 Vacuolar protein similar to mouse gene H
Chr3 (1) Chr4 (18) Chr5 (6) Chr6R (2) Total (27)
Arp6 binding 1 (100%) 17 (94%) 6 (100%) 1 (50%) 25 (93%) SWR1 Swr1 binding 1 (100%) 16 (89%) 6 (100%) 1 (50%) 24 (89%)
swr1 Arp6 binding 1 (100%) 17 (94%) 6 (100%) 2 (100%) 26 (96%)
Supplementary Table S4
arp6 swr1 arp6 log2 ratio swr1 log2 ratio t-test p-value t-test p-value
YLR075W 1.576571863 0.017433948 0.112996687 0.233670477 RPL10 Ribosomal protein L10 YPR102C 1.503365541 0.086560082 0.039075134 0.816923943 RPL11A Ribosomal protein L11A YGR085C 1.143842256 0.033554383 0.055413968 0.803008706 RPL11B Ribosomal protein L11B YDR418W 0.718618587 0.036794052 0.039131475 0.493819128 RPL12B Ribosomal protein L12B YDL082W 1.546588088 0.00398878 -0.104410618 0.59360929 RPL13A Ribosomal protein L13A YKL006W 1.711216572 0.023311062 0.275826444 0.029594461 RPL14A Ribosomal protein L14A YHL001W 1.703989493 0.014953649 0.219833568 0.025672879 RPL14B Ribosomal protein L14B YLR029C 1.326933388 0.202301454 -0.012165812 0.873990441 RPL15A Ribosomal protein L15A YMR121C 0.262738181 0.54140267 -0.251930545 0.055356559 RPL15B Ribosomal protein L15B YIL133C 1.094185355 0.015515901 0.329241219 0.020929948 RPL16A Ribosomal protein L16A YNL069C 1.31015634 0.051690657 0.090396094 0.365962411 RPL16B Ribosomal protein L16B YKL180W 1.451748954 0.002746471 0.322541961 0.038518029 RPL17A Ribosomal protein L17A YJL177W 1.348767919 0.002388861 0.282761947 0.074360115 RPL17B Ribosomal protein L17B YOL120C 1.241364565 0.047718353 0.16866299 0.136178652 RPL18A Ribosomal protein L18A YNL301C 1.224644755 0.036735933 0.219393383 0.113442069 RPL18B Ribosomal protein L18B YBR084C-A 0.770050182 0.112341057 -0.104795619 0.566028018 RPL19A Ribosomal protein L19A YBL027W 1.076896847 0.044605028 -0.188299044 0.495992786 RPL19B Ribosomal protein L19B YPL220W 1.64973779 0.034391114 0.377126871 0.031157561 RPL1A Ribosomal protein L1A YGL135W 1.595980048 0.008230744 0.465602625 0.017986272 RPL1B Ribosomal protein L1B YMR242C 0.690366606 0.282041695 0.448165749 0.009202752 RPL20A Ribosomal protein L20A YOR312C 0.990083064 0.096464011 0.035950894 0.807549645 RPL20B Ribosomal protein L20B YBR191W 0.575714408 0.535778578 0.080457252 0.439970647 RPL21A Ribosomal protein L21A YPL079W 0.571266803 0.165667904 0.058829957 0.725960444 RPL21B Ribosomal protein L21B YLR061W 0.728940999 0.121321702 -0.08532118 0.674349486 RPL22A Ribosomal protein L22A YBL087C 1.69104705 0.026184735 0.387822345 0.047703769 RPL23A Ribosomal protein L23A YER117W 2.319339736 0.092618174 0.466867458 0.126093501 RPL23B Ribosomal protein L23B YGL031C 1.254458262 0.099772146 -0.056718833 0.792606769 RPL24A Ribosomal protein L24A YGR148C 0.818354508 0.047120709 -0.16705702 0.555549897 RPL24B Ribosomal protein L24B YOL127W 1.456429685 0.09342639 0.208395546 0.264660289 RPL25 Ribosomal protein L25 YLR344W 0.973505719 0.139205774 0.137073308 0.211779795 RPL26A Ribosomal protein L26A YGR034W 1.397907971 0.129421428 0.291451143 0.147152203 RPL26B Ribosomal protein L26B YHR010W 1.528535589 0.093482478 -0.034577612 0.875676605 RPL27A Ribosomal protein L27A YDR471W 1.407346931 0.127932715 0.080286664 0.720570589 RPL27B Ribosomal protein L27B YGL103W 2.029320192 0.097768807 0.135393296 0.213072135 RPL28 Ribosomal protein L28 YIL018W 2.978587365 0.194555902 0.507191111 0.161837926 RPL2B Ribosomal protein L2B YOR063W 0.892834569 0.084445822 0.110501298 0.486864495 RPL3 Ribosomal protein L3 YGL030W 2.178075603 0.02767725 0.512600129 0.038983735 RPL30 Ribosomal protein L30 YDL075W 1.734797453 0.059763772 -0.16965972 0.560638925 RPL31A Ribosomal protein L31A YLR406C 1.25091373 0.075413742 -0.041507497 0.894930265 RPL31B Ribosomal protein L31B YBL092W 1.359675889 0.089999806 0.242349467 0.22278823 RPL32 Ribosomal protein L32 YPL143W 1.653014178 0.126867438 0.651822312 0.006328347 RPL33A Ribosomal protein L33A YOR234C 1.878918969 0.081449834 0.448106535 0.051091459 RPL33B Ribosomal protein L33B YER056C-A 1.171852004 0.026749893 0.409069495 0.072603787 RPL34A Ribosomal protein L34A YIL052C 1.135289748 0.044008456 0.35202333 0.146665611 RPL34B Ribosomal protein L34B YDL191W 0.617598406 0.254340889 -0.560365742 0.036213696 RPL35A Ribosomal protein L35A YDL136W 0.519972334 0.169363829 -0.586988481 0.092290158 RPL35B Ribosomal protein L35B YMR194W 0.713577359 0.1215553 -0.19266631 0.328706373 RPL36A Ribosomal protein L36A YPL249C-A 0.355551874 0.029598733 0.170414026 0.159052711 RPL36B Ribosomal protein L36B YLR185W 1.831915496 0.034272318 0.449438989 0.071399531 RPL37A Ribosomal protein L37A YDR500C 0.866460723 0.052853159 0.097665805 0.419301977 RPL37B Ribosomal protein L37B YLR325C 0.958288036 0.193460941 -0.056435274 0.809187635 RPL38 Ribosomal protein L38 YJL189W 1.383478986 0.097065658 -0.471087861 0.165259003 RPL39 Ribosomal protein L39 YKR094C 0.758839088 0.071383931 -0.038509012 0.866418261 RPL40B Ribosomal protein L40B YDL184C -0.02689704 0.95241093 -0.175430861 0.572890186 RPL41A Ribosomal protein L41A YNL162W 1.726442781 0.044789656 0.083662557 0.74203321 RPL42A Ribosomal protein L42A YHR141C 1.518585016 0.071401945 0.362117748 0.070641919 RPL42B Ribosomal protein L42B YBR031W 1.613544394 0.07541802 0.301061615 0.252079647 RPL4A Ribosomal protein L4A YDR012W 1.365812533 0.064550535 0.217296272 0.215143703 RPL4B Ribosomal protein L4B YPL131W 0.578322395 0.148144899 0.363739205 0.086329399 RPL5 Ribosomal protein L5 YML073C 1.026189219 0.00333147 0.273738884 0.143152681 RPL6A Ribosomal protein L6A YLR448W 0.870035304 0.077988032 0.277268059 0.052808158 RPL6B Ribosomal protein L6B YGL076C 0.853779945 0.050831096 0.374890396 0.039602658 RPL7A Ribosomal protein L7A YPL198W 1.127010707 0.055990742 0.282183649 0.057709776 RPL7B Ribosomal protein L7B YHL033C 1.16890719 0.014402862 0.301355911 0.00110139 RPL8A Ribosomal protein L8A YLL045C 0.927534009 0.036665972 0.346942815 0.010682521 RPL8B Ribosomal protein L8B YGL147C 2.001154361 0.033862605 0.058206669 0.780159902 RPL9A Ribosomal protein L9A YNL067W 1.360106999 0.204133244 0.202517895 0.320819612 RPL9B Ribosomal protein L9B YLR340W 0.025499589 0.9495506 0.634196687 0.015277129 RPP0 Ribosomal protein P0 YDL081C 2.308299563 0.013332031 0.745970418 0.029550652 RPP1A Ribosomal protein P1A YDL130W 1.828980435 0.017651205 0.438306831 0.011905829 RPP1B Ribosomal protein P1B YOL039W 1.214419471 0.025383298 0.597341306 0.016506898 RPP2A Ribosomal protein P2A YDR382W 2.220277424 0.066689938 0.428438433 0.003750935 RPP2B Ribosomal protein P2B YGR214W 0.905528953 0.004652697 0.316660171 0.010957085 RPS0A Ribosomal protein S0A YLR048W 1.277592787 0.000666966 0.367912657 0.015997253 RPS0B Ribosomal protein S0B YOR293W 1.414780311 0.164617553 0.012701869 0.952507416 RPS10A Ribosomal protein S10A YMR230W 1.253409032 0.144050522 -0.159201712 0.194064455 RPS10B Ribosomal protein S10B YDR025W 1.14703072 0.119007804 0.332549467 0.167976165 RPS11A Ribosomal protein S11A YBR048W 0.603507542 0.135601762 0.102493926 0.627849268 RPS11B Ribosomal protein S11B YOR369C 1.336069696 0.017229433 0.383564205 0.040907236 RPS12 Ribosomal protein S12 YDR064W 1.542230434 0.055859956 0.376037692 0.013764765 RPS13 Ribosomal protein S13 YJL191W 0.540641251 0.003421781 0.505068838 0.081178073 RPS14B Ribosomal protein S14B YOL040C 1.633716594 0.079449594 0.753295478 0.012005814 RPS15 Ribosomal protein S15 YMR143W 1.675148389 0.054405733 0.413165616 0.055348219 RPS16A Ribosomal protein S16A YDL083C 1.912603939 0.019191167 0.226168195 0.025123929 RPS16B Ribosomal protein S16B YDR447C 1.055119248 0.089987338 -0.489944811 0.08489435 RPS17B Ribosomal protein S17B YDR450W 1.329530264 0.047370355 -0.073409286 0.687153255 RPS18A Ribosomal protein S18A YOL121C 0.825853142 0.170781372 0.069472833 0.663066825 RPS19A Ribosomal protein S19A YNL302C 1.123946631 0.041669051 -0.105847454 0.494486498 RPS19B Ribosomal protein S19B YLR441C 1.554494625 0.166890011 -0.404773963 0.090185628 RPS1A Ribosomal protein S1A YML063W 1.742679322 0.058802357 -0.16214849 0.452235157 RPS1B Ribosomal protein S1B YGL123W 1.47580959 0.176326389 0.298163085 0.176786808 RPS2 Ribosomal protein S2 YHL015W 0.874570837 0.062183127 -0.346054478 0.095767284 RPS20 Ribosomal protein S20 YKR057W 1.164659345 0.1987206 0.044276269 0.307570824 RPS21A Ribosomal protein S21A YJL136C 1.509979603 0.034059717 0.192101201 0.379496244 RPS21B Ribosomal protein S21B YJL190C 2.572114824 0.090893172 0.523757623 0.005975725 RPS22A Ribosomal protein S22A YLR367W 1.269342224 0.235430992 0.518766245 0.021357709 RPS22B Ribosomal protein S22B YGR118W 1.905998532 0.143971105 -0.055413475 0.723544445 RPS23A Ribosomal protein S23A YPR132W 1.177776226 0.068429047 -0.212282965 0.138163103 RPS23B Ribosomal protein S23B YER074W 1.118645861 0.072797967 -0.024958046 0.840624872 RPS24A Ribosomal protein S24A YIL069C 1.146720758 0.044086876 -0.070902167 0.675752713 RPS24B Ribosomal protein S24B YGR027C 0.639048422 0.02798567 0.129112644 0.028986798 RPS25A Ribosomal protein S25A YLR333C 0.744924166 0.033454689 0.276893329 0.054096625 RPS25B Ribosomal protein S25B YGL189C 1.432802172 0.091822196 0.132248912 0.42787916 RPS26A Ribosomal protein S26A YER131W 0.771749498 0.071319758 0.089119006 0.601657361 RPS26B Ribosomal protein S26B YKL156W 0.906673867 0.032753132 0.142785112 0.097662666 RPS27A Rribosomal protein S27A YHR021C 2.175756787 0.027671927 0.690090147 0.023466091 RPS27B Ribosomal protein S27B YOR167C 2.18862899 0.036062185 0.784300702 0.001449006 RPS28A Ribosomal protein S28A YLR264W 1.727777615 0.01815399 0.103972173 0.026067351 RPS28B Ribosomal protein S28B YLR388W 0.713353266 0.118570613 0.65984373 0.058852725 RPS29A Ribosomal protein S29A YDL061C 0.916519867 0.059769261 0.896321501 0.017545271 RPS29B Ribosomal protein S29B YNL178W 1.577656862 0.187456364 0.038613614 0.803836227 RPS3 Ribosomal protein S3 YOR182C 0.945503037 0.032809985 -0.120139795 0.648470329 RPS30B Ribosomal protein S30B YLR167W 2.061228552 0.086881979 0.330792457 0.225867271 RPS31 Ribosomal protein S31 YJR145C 1.773813298 0.048126769 0.406672043 0.003345234 RPS4A Ribosomal protein S4A YHR203C 1.426400066 0.003420178 0.455713295 0.040050033 RPS4B Ribosomal protein S4B YJR123W 1.901269634 0.035313686 0.739036829 0.000987969 RPS5 Ribosomal protein S5 YPL090C 1.388847488 0.106165412 -0.310677624 0.139494895 RPS6A Ribosomal protein S6A YBR181C 1.517480365 0.18681994 -0.277696415 0.046526669 RPS6B Ribosomal protein S6B YOR096W 1.513057506 0.030362232 -0.140771101 0.393280483 RPS7A Ribosomal protein S7A YNL096C 0.949885526 0.040835327 -0.082916416 0.741138909 RPS7B Ribosomal protein S7B YBL072C 2.202569138 0.067628298 0.170422683 0.317507363 RPS8A Ribosomal protein S8A YER102W 2.076633921 0.067946003 0.196567561 0.245329992 RPS8B Ribosomal protein S8B YPL081W 0.961701165 0.036377962 0.079640792 0.628228217 RPS9A Ribosomal protein S9A YBR189W 0.950615102 0.051056367 0.047228918 0.81597576 RPS9B Ribosomal protein S9B Supplementary Table S5. Genes markedly down-regulated in arp6 cells
arp6/wt ORF name Gene name Description log2 ratio YNR034W-A -4.32 Hypothetical protein YOL052C-A -4.16 DDR2 Induced by DNA damage, heat shock, osmotic shock, etc YDR070C -3.90 FMP16 Hypothetical protein YBR072W -3.85 HSP26 Heat shock protein 26 YHR139C -3.73 SPS100 Sporulation-specific wall maturation protein YGR088W -3.31 CTT1 Cytoplasmic catalase T YMR105C -3.21 PGM2 Phosphoglucomutase YGR052W -3.16 FMP48 similarity to ser/thr protein kinases YCR021C -3.11 HSP30 Induced by heat shock, ethanol treatment Unknown function, expression is regulated by phosphate YDR281C -3.09 PHM6 levels YGR248W -3.05 SOL4 Similar to SOL3 YML128C -2.95 MSC1 Unknown function YMR175W -2.95 SIP18 Induced by osmotic stress YFL014W -2.92 HSP12 12 kDa heat shock protein YMR250W -2.82 GAD1 Glutamate decarboxylase, involved in oxidative stress YBR050C -2.74 REG2 Putative Glc7 regulatory subunit YMR107W -2.67 SPG4 Required for survival at high temperature YBR285W -2.66 Hypothetical protein YMR206W -2.63 Weak similarity to hypothetical protein YNR014w YHR140W -2.61 Hypothetical protein YGR256W -2.60 GND2 Zink-finger 6-phosphogluconate dehydrogenase YPL054W -2.57 LEE1 Unknown function YEL011W -2.50 GLC3 1,4-glucan-6-(1,4-glucano)-transferase YLR178C -2.47 TFS1 Lipid binding protein (putative) YER103W -2.46 SSA4 Member of 70 kDa heat shock protein family YPL223C -2.42 GRE1 Hydrophilin of unknown function, stress-induced YPR192W -2.40 AQY1 Aquaporin YLL026W -2.39 HSP104 104 kDa heat shock protein YOR186W -2.38 Hypothetical protein YMR081C -2.38 ISF1 Involved in mRNA splicing YDL085W -2.37 NED2 Mitochondrial external NADH dehydrogenase YMR169C -2.36 ALD3 Aldehyde dehydrogenase YGL156W -2.31 AMS1 Vacuolar alpha mannosidase YLL052C -2.25 AQY2 Aqy2p, putative aquaporin, member of MIP family YGL256W -2.24 ADH4 Alcohol dehydrogenase isoenzyme IV YDL022W -2.24 GPD1 Glycerol-3-phosphate dehydrogenase YJL163C -2.23 Hypothetical protein YDR247W -2.22 VHS1 Cytoplasmic serine/threonine protein kinase YOL083W -2.22 Similarity to YOL082w YER067W -2.20 Strong similarity to hypothetical protein YIL057c
Supplementary Table S6. Strains used in this study
Name Genotype GA-426 MATa ade2::hisG his3-11 leu2 trp1 ura3-52 can1::hisG VR::ADE2-TEL GA-3353 GA-426 arp6::ARP6-3FLAG-Kan GA-3354 GA-3353 swr1::TRP1 GA-3153 GA-426 swr1::SWR1-3FLAG-Kan GA-3477 GA-426 sir4::SIR4-x3FLAG-Kan GA-1320 MATa ade2-1 can1-100 his3-11,-15::GFP-LacI-HIS3 trp1-1, ura3-1, leu2-3,-112 nup49::NUP49-GFP-URA3 GA-1461 GA-1320 PES4::lacO-lexA-TRP1 (integrated 272 bp 5’ of PES4). GA-3320 GA-1461 swr1::CaURA3 GA-2765 GA-1461 mlp1::KanMX6 mlp2::CaURA3 GA-2659 GA-1320 LYS2::lacO-lexA-TRP1 GA-4135 MATalpha hml::ADE1 hmr::ADE1 ade3::GALHO nup133::NUP133-13myc-Kan GA-5806 GA-4135 arp6::TRP1 GA-5807 GA-4135 swr1::TRP1 GA-5868 GA-3353 htz1::TRP1 GA-3150 arp6::ARP6-3FLAG-Kan ade2-1 can1-100 his3-11,-15 trp1-1 ura3-1, leu2-3,-112 GA-3203 GA-3150 swr1::CaURA3 GA-3426 GA-3425 arp6::KanMX6 GA-3427 GA-3425 swr1::CaURA3 GA-3428 MATa, ade2-1 can1-100 his3-11,-15 trp1-1 ura3-1 leu2-3,-122 ino80::INO80-13MYC-HIS3MX6 GA-3429 GA-3428 arp6::KanMX6 GA-3430 GA-3428 swr1::CaURA3 GA-4584 MATa ade2-1 ::GFP-LacI-ADE2 can1-100 his3-11,-15 trp1-1, ura3-1, leu2-3,-112 nup49::NUP49-CFP-URA3 LYS2::LacO-LexA-TRP1 nup133::HIS3 pUN100-nup133ΔN-KanMX6 GA-3635 GA-1320 with RPL9A::LacO-TRP1 GA-5113 GA-3635 with swr1::CaURA3 GA-5132 GA-3635 with arp6::CaURA3 GA-4098 GA-1320 with GAL10::LacO-TRP1 GA-6024 GA-4098 with arp6::CaURA3
Text S1. Supplementary Materials
Primer sequences For RPS16B: forward primer, TCACTGGTGGTGGTCATGTT; reverse primer, CGTTCTTGGATTGTTCGTCA For RPL13A: forward primer, GCACTGGCAAGAACGTGTTA; reverse primer, GCAGCAGCAGACAAAACTTG For RPP1A: forward primer, TGGCTGACTCTGAAATCGAA; reverse primer, CGTCCAAAGCCTTAGCAAAA For RPL31A: forward primer, GCTCCAGAATTGAACCAAGC; reverse primer, TGGCGTCTTCTTCTTCGTTT For RPL2A: forward primer, ACCTCCCACACCAGATTGAG; reverse primer, CTACCGGAGTCGTGGACAAT For RPL29: forward primer, AACCAAACCAGAAAGGCTCA; reverse primer, GTAGGGCATGCTTGTGGTTT For NUP2: forward primer, TAAGGTTGCGTCATCTGCTG; reverse primer, CTGCTTGGTTTCATCCGATT For FAB1: forward primer, GCGACGGATTTGAACACATT; reverse primer, ATATTCGCGCTCTTGCCTAA. For PES4: forward primer, CGAGCCATTCTGATTCACCT; reverse primer, TGTTTCATGGAGGTCACCAA. For GAL1: forward primer, GCGCAAAGGAATTACCAAGA; reverse primer, GGCGCAAAGCATATCAAAAT For SWR1: forward primer, GCTTCCTCTGGTTCAGATGC; reverse primer, AGACAAGGGTTCCGATGATG For UBX3: forward primer, GGGATGGACGCTTAAAATCA; reverse primer, AAACGGTTGTGCTTCCTCTG For RDS1: forward primer, GTGATAAACTGCGGCCTGCT; reverse primer, AACGACACCTTCAGGCACTT For RPL13A: forward primer, TCTGTTCGAAGGGGTTTGAG; reverse primer, TACGATTCCTGCTGTGCTGT For RPS16B: forward primer, TCACTGGTGGTGGTCATGTT, reverse primer, CGTTCTTGGATTGTTCGTCA