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UNITED STATES BIOPHARMACEUTICALS 2020 BIOPHARMACEUTICALS UNITED STATES UNITED STATES BIOPHARMACEUTICALS 2020 Research and Development - Contract Services - Drug Discovery Academic Research Regulations and Compliance - East Coast Hubs - Logistics and Distribution Amos i m 0 0 5 Fredericton Timmins Quebec i m 0 0 4 The East Coast Corridor: MAINE i m Bangor The Heart of 0 0 American Biopharma 3 Montreal Augusta Dear Reader, i Ottawa m 0 VERMONT CANADA 0 2 Montpelier NEW HAMPSHIRE Portland Kingston i The United States Biopharmaceutical industry is widely envied m 0 0 Concord around the world, and for good reason. From gene editing, to cell- 1 Welcomebased to therapies, the 2020 toedition profoundly of the new US Biopharmaceuticalways of manipulating Industry immune Report, a jointcells GBR-CPhI to target analysis. cancers, Thetoday’s United science States is being Biopharmaceutical translated into industryprac- is Toronto widelytical envied treatments around forthe patients world, and at breakneck for good reason.speed. FromBiopharma gene editing,com- to MICHIGAN Albany BOSTON cell-basedpanies therapies, have achieved to profoundly remarkable new progressways of manipulating in advancing immune early dis cells- to Rochester MASSACHUSETTS targetease cancers, detection today’s and science enabling is being targeted translated treatments into practical with limited treatments side for NEW YORK patientseffects. at breakneck These innovations speed. Biopharma have catalyzed companies significant have reductionsachieved remark in - Buffalo Providence able theprogress number in advancingof deaths dueearly to disease cancer, detectionHIV/AIDS, andand enablingautoimmune targeted Hartford RHODE ISLAND treatmentsdiseases with across limited the side world. effects. This Theseprovides innovations reasons forhave optimism catalyzed that signifi - Lansing i 0m cant reductions in the number of deaths due to cancer, HIV/AIDS, and auto- Detroit 10 CONNECTICUT America’s dynamic life sciences industry will be able to collectively i immunerise diseasesto the occasion across the and world. defeat This the provides novel COVID-19 reasons forvirus optimism that is that m 0 America’s dynamic life sciences industry will be able to collectively rise to the Erie 0 2 bedeviling society today. NEW YORK occasion and defeat the novel COVID-19 virus that is bedeviling society today. Jersey City As we move through these uncertain times, it is crucial for inves- Cleveland PENNSYLVANIA As wetors, move pharmaceutical through these executives, uncertain times,and scientific it is crucial researchers for investors, involved pharma - TRENTON ceutical executives, and scientific researchers involved in the US biopharma- GREATER in the US biopharmaceutical industry to remain together and in- ceutical industry to remain together and informed. The way in which groups Pittsburgh Harrisburg PHILADELPHIA formed. The way in which groups across industry, academia, gov- across industry, academia, government, and the broader health-care system OHIO NEW JERSEY ernment, and the broader health-care system have come together Wilmington have tocome fight together this pandemic to fight thishave pandemicbeen inspiring. have beenIndeed, inspiring. continuing Indeed, to con- tinuingpartner to partner in this in way this willway be will critical be critical in successfully in successfully navigating navigating public public i Baltimore m health challenges of the future. That is the essence of why events like CPhI Columbus 0 health challenges of the future. That is the essence of why events 0 Dover 3 MARYLAND Northlike America CPhI Northexist. America exist. Annapolis Dayton Washington D.C. DELAWARE The followingThe following pages pages offer widespreadoffer widespread coverage coverage of the stateof the of state the USof thebiophar - maceuticalUS biopharmaceutical industry, including industry, big pharma including and its big blockbuster pharma and drugs, its block emerging- Cincinnati WEST biotech and their innovative drug pipelines, and the different service providers VIRGINIA buster drugs, emerging biotech and their innovative drug pipelines, acrossand the the value different chain, service from CDMO’s providers and across CRO’s the to value AI and chain, big fromdata CDplatform- companies. Charleston MO’s and CRO’s to AI and big data platform companies. VIRGINIA We sincerely hope that you have a great conference, full of business and net- Frankfort We sincerely hope that you have a great conference, full of business i Richmond workingand opportunities. networking opportunities. Thank you for Thank your participationyou for your inparticipation CPhI North in Amer - m 0 0 ica, and we hope you enjoy reading our 2020 edition of the United States Lexington 4 Norfolk CPhI North America, and we hope you enjoy reading our 2020 edi- Roanoke Biopharmaceuticaltion of the United Industry States Report. Biopharmaceutical Industry Report. N.C. Atlantic Ocean KENTUCKY DURHAM RESEARCH TRIANGLE CHAPEL HILL RALEIGH Asheville NORTH Knoxville i m 0 Charlotte CAROLINA 0 TENNESSEE 5 Chattanooga Greenville SOUTH Alice Pascoletti Anthony Pombal Columbia Managing DirectorDirector Brand Director Huntsville CAROLINA Global Business Reports CPhI North America Atlanta GEORGIA Augusta Charleston Savannah Montgomery Editorial Introducing the US 35. Interview with Ernst & Young 57. Interview with Eloxx Pharmaceuticals 75. Interview with Alira Health Industry Outlook Biopharmaceutical Industry 36. Interview with Signet Healthcare Partners 58. Responding to COVID-19 76. Interviews with CordenPharma Group Analysis 37. To List or not to List 59. Interview with Aphios and with Visikol 98. Conclusion 8. The Moral Imperative to Innovate 39. Interview with Burrage Capital 60. Commercializing Neuroscience 77. Interviews with Avēma Pharma Solutions 99. Comments from Nicos Group, 11. Interview with Porzio Life Sciences 61. Interview with Terran Biosciences and with ACG Capsules Pharmalex and Hart & Reed-Lane GBR provides unique 14. Interview with Nivagen Pharmaceuticals 62. Originating Discovery 78. Generics 100. Concluding Thoughts and first-hand analysis 15. Interview with Pfizer 63. Interview with Princeton 81. Interview with Advantice Health 102. Company Directory into all aspects of the US 16. Introducing the hubs Accelerating Pipelines: Entrepreneurship Council 82. Interview with Dr. Reddy’s Laboratories 104. Credits biopharmaceutical industry 20. Interview with BIONJ Drug Discovery and Development 64. Interview with Rutgers 83. Interview with Servier Group after months on the ground 22. Interview with MassBio 65. Interview with Roux Institute of 42. Top 10 U.S. Biopharmaceutical Northeastern University Companies Based on Revenue 8, 26, 43, 68, 43. Drug Development and Discovery Technology and USA BIOPHARMACEUTICALS 2020 44. Interview with Onosec Medical Industry Explorations The Biopharma Investment Climate Regulatory Services Global Business Reports 86, 98.... 47. Interview with Goldfinch Bio Contract Manufacturing 26. From Bull Market to Uncertainty This research has been conducted by 48. Advancing Oncology and Generics 86. Disruptive Technology Lucrezia Falcidia, Jason Spizer and 28. Interview with Third Rock Ventures 49. Interview with Stemsynergy Therapeutics 87. Interview with AiCure Maria Filippova Barnachisnkaya 29. Interview with XOMA 51. Interview with Cyclacel Pharmaceuticals 68. Contract Development and Manufacturing 89. Interview with Decision Resources Group Edited by Mungo Smith 30. Interview with Atlas Venture 52. Interview with Hillstream Biopharma 70. Interview with Cambrex 90. Interview with Pharmafusion Graphic design by Gonzalo Da Cunha 31. Interview with J.W. Childs Associates 53. Interview with InteRNA Technologies 71. Interview with GVK BIO 91. Interview with Cardinal Health A Global Business Reports Publication 32. Merger Spree 54. Expanding Therapeutic Focus 72. Interview with Piramal Global Pharma 92. Regulatory Services For updated industry news from our 34. Interview with J.P. Morgan on-the-ground teams around the world, 55. Interview with AzurRX Biopharma 73. Interview with Sunrise Pharmaceuticals 93. Interview with Systech International please visit our website at gbreports.com, subscribe to our Commercial Banking 56. Interview with Hepion Pharmaceuticals 74. Interview with Contract Pharmacal Corp 94. Interviews with Adents and with Tracelink newsletter by signing up to our VIP list through our website, or follow us on Twitter: @GBReports CONTENTS / USA Biopharmaceuticals 2020 Exclusive Interviews Olympia Washington CANADA Leading industry figures North Maine Salem Dakota Minnesota share their insights and Helena Montana Bismarck exciting new developments Augusta Idaho Montpelier with GBR Oregon New Vermont United States Boise Hampshire St. Paul New York Concord of America South Pierre Albany Boston 11, 15, 55, 56, Dakota Wisconsin Michigan International Boundary State Boundary Wyoming Providence Lansing Hartford Rhode Island 81, 87... State Capital Madison Connecticut Pennsylvania Iowa Carson City Cheyenne Harrisburg Trenton N Nebraska Salt Lake City Des Moines Sacramento Illinois Columbus Ohio Dover Nevada Lincoln Indianapolis Delaware Denver Springfield Annapolis Maryland Utah Topeka Indiana Washington D.C. 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