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CAN COMPUTERS AID IN THE DESIGN OF ORGANIC SYNTHESIS AMD SHOULD THEY? The computer/chemist symbiosis — an analysis of a team approach fo solving organic synihesis and an evaluation of the potential advantages of doing so. April 13, 1978, Mount b'ofyoke Coiiege 8;00 p.m., Cleveland Hal! L2 ON THE REPRESENTATION OF CHEMICAL REACTIONS The symbolic representation of chemistry so the computer can understand, solve, and evaluate chemical reactions as a chemist does. April 14, 1970, Amherst College 3:30 p.m., Lecture Room 2, Science Center

SYNTHETIC STRATEGIES AND HIGHER LEVEL (\KlAOWi\itfNiW Synthesis planning — uses of symmetry, convergent synthesis, etc. and progress in teaching these concepts to the computer April 14, 1978, Ssr.iih ColSegs 8:00 p.m., Room 103, AlcConnell Hc,!i

ISOMER ENUMERATION, MECHANISTIC STUDIES AND BIO'OGICAI ASMiCATinNS How ihe computer can enumerate skeletal and stereochemical isomers polycyclic compounds, of determine the possible mechanisms of rearrangement processes, and de- duce plausible biosyniheiic and metabolic pathways. April 15, 1978, University Gr'/VVissethuse-lls, 10:30 a.m., Peters Audiio;kw, Goes-nan Laboratory

On-line dciwmsfrcrtions P tfio computer system will be given

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\ SPE/KERS

Four 1-Co lieye Chemistry Lecture Series (Amherst, Mount Holyoke & Smith Colleges; University of Massachusetts)

1951-1932 Duncan Maclnnes, Rockefeller' Institute 1934-1935 Roger Adams, University of Illinois 1935-1936 George B. Kistiakowsky , Harvard University . 1937-1938 Hugh S. Taylor, Princeton University 1938-1930 Hans T. Clarke, Columbia University

1939-1940 Linus Pauling, California Institute of Technology 1940-1941 R. P. Linstead, Harvard University 1941-1942 Lectures omitted because of appointment of Dr. Dorothy Wrinch as pint visiting lecturer to Amherst, Smith and Mount Holyoke. .. ' 1942-1943 Kasimir Fajans, University of Michigan 1947-1948 William S. Johnson, University of Wisconsin 1948-1949 Vincent dv Vigneaud', Cornell Medical School 1950-1951 Peter Debye, / Cornell University 1951-1952 John Roberts, Massachusetts Institute of Technology 1952-1953 Pierce W. Selwood,' Northwestern University. 1953-1954 William yon E..Doering, Yale University 1954-1955 John C. Bailor,' University of Illinois 1955-1956 E, J. Corey, University .of Illinois 1956-1957 Henry Eyring, 'University of Utah- 1958-1959 Paul D. Bartlett, .Harvard University 1959-1960 Philip J. Living, '.University of Michigan

1960-1961 E. W. R. Steacie, National Research Council, Ottawa 1961-1962 Louis F. Fieser, Harvard University 1962-1963 William N. Lipscomb, Harvard University

1963-1964 Philip Handler,' Duke University.: ■

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■ I 1964-^1965 Jcrrold Meinwald, vncll UniuersUuIs 'I

I 1965-1066 Manfred Eigen, Max .'hoick Jnstitut fur Fhysikalische Chcmic, Gottingen

1966-1967 Dudley R. Herschbach, Harvard University

1967-1063 Kenneth B. Wiberg, Yale University

1968-1960 Donald J. Cram, University of California, Los Angeles 1969-1070 F. Albert Cotton, Massachusetts Institute of Technology 1970-1071 Howard K. Sohachman, University of California, Berkeley j 19(p\-1072 Paul J. Flory, Stanford University

Five-College Oiemistry Lecture Secies (Amlierst, \ Hampshire, Mount Holyoke & Smith Colleges; University of Mass ichusetts) 1972-1973 Michael J. S. Dewar, University of Tr.mr, 1975-1974 Konrad E. Bloch, Harvard University

1974-1975 Jean-Marie Lehn, Universale de Strasbourg

1975-1976 Ruth Hubbard, Harvard University

1976-1077 A. Lan Scott, Yale University / 1

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