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Trifluoperazine 1Mg/5Ml Syrup Can Trifluoperazine 1Mg/5Ml Syrup Have Effects on Muscle Control

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Trifluoperazine 1Mg/5Ml Syrup Can Trifluoperazine 1Mg/5Ml Syrup Have Effects on Muscle Control • Rarely patients may develop Neuroleptic Malignant Syndrome. This causes a high temperature, rigid muscles, drowsiness, occasional loss of consciousness, and requires emergency admission to hospital for treatment. PATIENT INFORMATION LEAFLET • If you have chest pain (angina) and your pain is getting worse. • Very occasionally, medicines such as Trifluoperazine 1mg/5ml Syrup can Trifluoperazine 1mg/5ml Syrup have effects on muscle control. If this happens, symptoms can include slurred speech, odd movements of the face, particularly of the tongue, eyes, head or neck (such as twisting of the neck which causes an Read all of this leaflet carefully before you start taking this medicine. unnatural positioning of the head, rigid muscles, tremors or restlessness Keep this leaflet. You may need to read it again. and difficulty in sitting still). Some patients (especially on high doses of If you have any further questions, ask your doctor or pharmacist. this medicine) experience problems with muscle control which may This medicine has been prescribed for you. Do not pass it on to others. It continue for years. Such patients may experience constant chewing or may harm them, even if their symptoms are the same as yours. tongue movements or other gentle movements of the neck, head or trunk. If any of the side effects become serious, or if you notice any side effects Uncontrollable movements of the arms and legs have also been reported not listed in this leaflet, please tell your doctor or pharmacist. in these patients. In this leaflet: • Occasionally, some patients have complained of feeling slowed down, 1. What Trifluoperazine 1mg/5ml Syrup is and what it is used for whilst • Rarely, jaundice (yellowing of skin and whites of eyes), eye problems, 2. Before you take Trifluoperazine 1mg/5ml Syrup skin colouring (pigmentation) and blood problems. 3. How to take Trifluoperazine 1mg/5ml Syrup • if you suffer from a sore throat, high fever, feel very tired, become pale, 4. Possible side effects develop bruises and nose bleeds. These may indicate blood problems 5. How to store Trifluoperazine 1mg/5ml Syrup developing as a result of using this medicine. 6. Further information • In elderly people with dementia, a small increase in the number of deaths 1. WHAT TRIFLUOPERAZINE 1mg/5ml SYRUP IS AND WHAT IT IS USED FOR has been reported for patients taking antipsychotics compared with those not receiving antipsychotics. Trifluoperazine 1mg/5ml Syrup contains the active ingredient trifluoperazine Some patients may also experience weakness, drowsiness, dizziness, hydrochloride, which belongs to a class of drugs called phenothiazine restlessness, difficulty in sleeping, dry mouth, blurred vision, muscle tranquilisers, also referred to as a neuroleptic drug. It influences the activity weakness, loss of appetite, faintness on standing up, skin rashes (including of certain brain cells by decreasing the effect of dopamine, a natural increased sensitivity to the sun), weight gain, water retention causing chemical in the brain. swelling or confusion. • At a low dose, Trifluoperazine 1mg/5ml Syrup is used to manage anxiety Your doctor should check your progress regularly if you are on and depression. It is used in this way for short periods of time. Trifluoperazine 1mg/5ml Syrup to make sure no unwanted effects are Trifluoperazine 1mg/5ml Syrup may also be used to treat nausea (feeling developing. sick) and vomiting (being sick). If any of the side effects become serious, or if you notice any side effects not • At high doses, Trifluoperazine 1mg/5ml Syrup is used to treat and prevent listed in this leaflet, please tell your doctor or pharmacist. relapses of schizophrenia (a serious mental illness). It can also be used 5. HOW TO STORE TRIFLUOPERAZINE 1mg/5ml SYRUP for short periods of time to treat bad agitation or dangerous behaviour. Keep this medicine out of the sight and reach of children. 2. BEFORE YOU TAKE TRIFLUOPERAZINE 1mg/5ml SYRUP Do not use Trifluoperazine 1mg/5ml Syrup after the expiry date which is DO NOT take Trifluoperazine 1mg/5ml Syrup if: stated on the box. The expiry date refers to the last day of that month. If your • You know that you are allergic to trifluoperazine hydrochloride or any of the Syrup is out of date, take it to your pharmacist who will get rid of it safely. other ingredients of Trifluoperazine 1mg/5ml Syrup (see section 6 of this Do not store above 25°C. Store in the original package. leaflet). 6. FURTHER INFORMATION • You are suffering from liver problems, blood disease, inability of the heart to maintain adequate circulation causing breathlessness and swelling of The active substance in Trifluoperazine 1mg/5ml Syrup is trifluoperazine the ankles. hydrochloride. Each 5ml spoonful of Syrup contains 1mg trifluoperazine present as hydrochloride. • If you have previously had to stop taking other medicines for psychiatric problems like trifluoperazine (known as phenothiazines) because they Trifluoperazine 1mg/5ml Syrup also contains sodium saccharin, sodium benzoate (E211), anhydrous citric acid (E330), sodium citrate, sorbitol have affected your blood cells or caused jaundice (yellowing of the skin (E420), quinoline yellow (E104), sunset yellow (E110), peach flavour and or eyes). Ask your doctor about this. purified water. Take special care with Trifluoperazine 1mg/5ml Syrup and tell your What Trifluoperazine 1mg/5ml Syrup looks like and contents of the doctor if you are: pack • suffering from any disease involving the heart and blood vessels Trifluoperazine 1mg/5ml Syrup is a clear pale yellow, peach flavoured syrup (cardiovascular disease) including chest pain (angina) and irregular heart beats and comes in amber glass bottles, containing 200ml syrup. • suffering from a brain disorder causing tremors, rigidity and slowing of Marketing Authorisation Holder movement (Parkinson’s disease) Mercury Pharmaceuticals Ltd., • suffering from fits (epilepsy) Capital House, 85 King William Street, London EC4N 7BL, UK • suffering from an eye disease called narrow angle glaucoma which Manufacturer causes increased pressure inside the eye, Laleham Health and Beauty Limited, • suffering from abnormal muscle weakness (Myasthenia gravis) Fairfield, Bradshaw Lane, Greenhalgh, Preston, Lancashire, PR4 3JA • suffering from an enlargement of prostate gland • exposed to extremes in temperature as this medicine can affect body This leaflet was last revised in December 2014. 101961/LF/139/05 temperature control 4 1 continued over • an elderly person Remember each 5ml spoonful of syrup contains 1mg of “Trifluoperazine” • if you suffer from loss of cognitive (memory, language, intelligence) ability - dementia. Patient Type Low dosage High dosage • if you or someone else in your family has a history of blood clots, as medicines like these have been associated with formation of blood clots. For the treatment of For the control of • If you have had a stroke or have any of the following that can increase your anxiety or nausea schizophrenia and risk of having a stroke (e.g. heart attack, uncontrolled high blood pressure, and vomiting related conditions diabetes, family history of strokes, you smoke or drink excess alcohol). Even though some of the above may appear obvious, it is important that your doctor is aware if any of them apply to you. Adults The usual dose is 2 mg to High dose in adults is 6mg a day 5-25mg a day in Taking other medicines Please tell your doctor or pharmacist if you are taking or have recently taken divided doses any other medicines, including medicines obtained without a prescription. The effects of these medicines may change, especially if you are taking: Elderly The starting dose of The starting dose of • sleeping tablets, (over 65 years of age) syrup should be no syrup should be no • strong pain killers (e.g. codeine) more than half that of more than half that of • medicines which result in lowering of blood pressure (e.g. guanethidine) adult patients adult patients • anticholinergic medicines used to reduce saliva and lung secretions (e.g. atropine, procyclidine) Children For children aged 3-5 High dose in children • antidepressants (e.g. other phenothiazines, lithium) years, the dose is no (aged 6-12 years) is • medicines for fits (anticonvulsants) • medicines for Parkinson’s disease (e.g. levodopa) more than 1mg a day. 5mg in divided doses. • blood thinning medicines (anticoagulants such as warfarin) For children aged 6-12 • medicines used to treat iron poisoning (desferrioxamine) years the dose is no • antacids used to treat indigestion. more than 4mg a day. • medicines for psychiatric conditions (neuroleptics) • heart medicines which prolong the QT interval (e.g quinidine, disopyramide, procainamide, amiodarone, sotalol) During treatment your doctor should regularly check you for physical side • drugs causing electrolyte imbalances (e.g diuretics) effects, changes in your blood counts or liver function, and any heart You should tell your doctor or dentist that you are taking Trifluoperazine problem, especially if you taking this medicine for a long time or are also before being given an anaesthetic. taking other medicines. Taking Trifluoperazine 1mg/5ml Syrup with food and drink You should not drink alcohol whilst you are taking this medicine. If you stop taking Trifluoperazine 1mg/5ml Syrup Trifluoperazine 1mg/5ml Syrup can be taken with or without food. Continue to take Trifluoperazine 1mg/5ml Syrup even if you no longer feel ill. Pregnancy and breast feeding Do not stop taking this medicine without talking with your doctor first, Do not take Trifluoperazine 1mg/5ml Syrup if you are pregnant, think you may especially if you have taken large doses for a long time. When the time be pregnant or are planning to become pregnant, or while breast feeding, comes to stop your doctor will probably decrease your dose gradually as unless your doctor decides that treatment is essential. It is particularly important not to take Trifluoperazine 1mg/5ml Syrup during the first three stopping the Syrup suddenly may cause ill-effects such as nausea (feeling months of pregnancy.
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